3W6RA

Crystal structure of the gap domain of human mgcracgap
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
200
structure length
200
Chain Sequence
MEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWSQFMMVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein
molecule keywords Rac GTPase-activating protein 1
publication title Crystal structure of GTPase-activating domain from human MgcRacGAP.
pubmed doi rcsb
source organism Homo sapiens
total genus 71
structure length 200
sequence length 200
ec nomenclature
pdb deposition date 2013-02-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3w6rA00
1PBWA 1OW3A 2EE4A 1F7CA 1GRNB 2XS6A 2QV2A 5IRCA 3KUQA 3WPQA 3EAPA 2OSAA 1TX4A 5HPYA 3IUGA 2NGRB 5C2JA 1AM4A 1XA6A 3MSXB 5C5SA 3W6RA 2EE5A 1RGPA 3CXLA 5JCPA 3FK2A 2OVJA 3QISA 3WPSA 3BYIA 2MBGA 5JD0A
chains in the Genus database with same CATH superfamily
1PBWA 1OW3A 2EE4A 1F7CA 1GRNB 2XS6A 2QV2A 5IRCA 3KUQA 3WPQA 3EAPA 2OSAA 1TX4A 5HPYA 3IUGA 2NGRB 5C2JA 1AM4A 1XA6A 3MSXB 5C5SA 3W6RA 2EE5A 1RGPA 3CXLA 5JCPA 3FK2A 2OVJA 3QISA 3WPSA 3BYIA 2MBGA 5JD0A
chains in the Genus database with same CATH topology
1PBWA 1OW3A 2EE4A 1F7CA 1GRNB 2XS6A 2QV2A 5IRCA 3KUQA 3WPQA 3EAPA 2OSAA 1TX4A 5HPYA 3IUGA 2NGRB 5C2JA 1AM4A 1XA6A 3MSXB 5C5SA 3W6RA 2EE5A 1RGPA 3CXLA 5JCPA 3FK2A 2OVJA 3QISA 3WPSA 3BYIA 2MBGA 5JD0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PBW A;  1OW3 A;  2EE4 A;  1F7C A;  1GRN B;  2XS6 A;  2QV2 A;  5IRC A;  3KUQ A;  3WPQ A;  3EAP A;  2OSA A;  1TX4 A;  5HPY A;  3IUG A;  2NGR B;  5C2J A;  1AM4 A;  1XA6 A;  3MSX B;  5C5S A;  3W6R A;  2EE5 A;  1RGP A;  3CXL A;  5JCP A;  3FK2 A;  2OVJ A;  3QIS A;  3WPS A;  3BYI A;  2MBG A;  5JD0 A; 
#chains in the Genus database with same CATH topology
 1PBW A;  1OW3 A;  2EE4 A;  1F7C A;  1GRN B;  2XS6 A;  2QV2 A;  5IRC A;  3KUQ A;  3WPQ A;  3EAP A;  2OSA A;  1TX4 A;  5HPY A;  3IUG A;  2NGR B;  5C2J A;  1AM4 A;  1XA6 A;  3MSX B;  5C5S A;  3W6R A;  2EE5 A;  1RGP A;  3CXL A;  5JCP A;  3FK2 A;  2OVJ A;  3QIS A;  3WPS A;  3BYI A;  2MBG A;  5JD0 A; 
#chains in the Genus database with same CATH homology
 1PBW A;  1OW3 A;  2EE4 A;  1F7C A;  1GRN B;  2XS6 A;  2QV2 A;  5IRC A;  3KUQ A;  3WPQ A;  3EAP A;  2OSA A;  1TX4 A;  5HPY A;  3IUG A;  2NGR B;  5C2J A;  1AM4 A;  1XA6 A;  3MSX B;  5C5S A;  3W6R A;  2EE5 A;  1RGP A;  3CXL A;  5JCP A;  3FK2 A;  2OVJ A;  3QIS A;  3WPS A;  3BYI A;  2MBG A;  5JD0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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