3WAXA

Crystal structure of autotaxin in complex with 3boa
Total Genus 261
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
261
Knots found
sequence length
805
structure length
789
Chain Sequence
WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDLEELNHTKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
pubmed doi rcsb
source organism Mus musculus
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
total genus 261
structure length 789
sequence length 805
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2013-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3waxA04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3waxA03
3T02A 3M8WA 4CYRA 1QAEA 4UOPA 5LQQA 4E3YA 4KAVA 1G8TA 3B5QA 4CXSA 1KH7A 5L0BA 2XH3A 4A1NA 1ZM8A 2IFYA 3OT9A 4UPLA 3IDDA 3Q3QA 4QAXA 1EW8A 1E1ZP 3BDGA 3NKPA 4KM4A 1P49A 5IJQA 1ALHA 4MY4A 3NKMA 4UORA 4LR8A 1ZEDA 1EW2A 1SHQA 4LRFA 2W5RA 3M8ZA 3ISMA 4ZGAA 3NVLA 1KHLA 3T01A 3KD8A 1ZEFA 3BDHA 4LRBA 3UN5A 4LRAA 4QGOA 2GLQA 4QH0A 1N2LA 4YR1A 2GA3A 2G9YA 2QZUA 2IUCB 1AJAA 4B56A 1AJBA 1HDHA 1ZEBA 3CMRA 1B8JA 3IGZB 4UOOA 1ANJA 5DLTA 3WBHA 3ED4A 2GSUA 2W5XA 2XR9A 1E3CP 3UO0A 3BDGB 4UPHA 5C66A 4ZG6A 1ELZA 3A52A 2IUCA 3UNYA 4LREA 5TJ3A 2GSOA 4GTWA 4LRDA 1KHJA 5INHA 3M7VA 2XGRA 5DLVA 5GRRA 1ELXA 4N7TA 3NKRA 2X98A 3UN3A 4CXKA 1ALJA 4GTXA 4KJDA 5LIAA 5GKPA 2ANHA 3BDFA 3MK0A 3WAVA 3WAWA 4CXUA 1ALIA 3OWVA 4GTYA 2W5WA 1AUKA 3NKOA 4UPIA 2GSNA 1ELYA 3UN2A 3M8YA 1KHNA 1O98A 5EGEA 5L0KA 2D1GA 1SMNA 4NWXA 4GTZA 4LR9A 1SHNA 4ZG7A 1AJDA 1N2KA 5EGHA 3MK1A 2W8DA 5DLWA 1HQAA 3TWZA 4FDJA 3TG0A 4LQYA 1EI6A 1KH9A 1EW9A 1URAA 4FDIA 3DPCA 4LRCA 2O3BA 3WAYA 3E2DA 1EJJA 1KH4A 1E33P 1QL0A 4MIVA 1Y7AA 3WAXA 1URBA 1E2SP 5HRTA 3NKNA 3S5BA 1ANIA 2XRGA 5L0EA 1KHKA 5GOVA 4KAYA 2VQRA 3LXQA 3SZZA 5GKCA 1O99A 1FSUA 4KJGA 4LR2A 2ZKTA 1Y6VA 3NKQA 3DYCA 5K4PA 1HJKA 3MK2A 4MHXA 4UPKA 2W5QA 5KXAA 1AJCA 2W8SA 1ED9A 2RH6A 5LRNA 4LR7A 3T00A 5LRMA 2W5VA 1KH5A 4CYSA 4TN0A 3IGYB 2W5SA 4QN0A 4NWJA 1ALKA 2W5TA 1ED8A 4ZG9A 5AJ9A 3SZYA 1EQJA 3TX0A 1K7HA 5IJSA
chains in the Genus database with same CATH superfamily
3T02A 3M8WA 4CYRA 1QAEA 4UOPA 5LQQA 4E3YA 4KAVA 1G8TA 3B5QA 4CXSA 1KH7A 5L0BA 2XH3A 4A1NA 1ZM8A 2IFYA 3OT9A 4UPLA 3IDDA 3Q3QA 4QAXA 1EW8A 1E1ZP 3BDGA 3NKPA 4KM4A 1P49A 5IJQA 1ALHA 4MY4A 3NKMA 4UORA 4LR8A 1ZEDA 1EW2A 1SHQA 4LRFA 2W5RA 3M8ZA 3ISMA 4ZGAA 3NVLA 1KHLA 3T01A 3KD8A 1ZEFA 3BDHA 4LRBA 3UN5A 4LRAA 4QGOA 2GLQA 4QH0A 1N2LA 4YR1A 2GA3A 2G9YA 2QZUA 2IUCB 1AJAA 4B56A 1AJBA 1HDHA 1ZEBA 3CMRA 1B8JA 3IGZB 4UOOA 1ANJA 5DLTA 3WBHA 3ED4A 2GSUA 2W5XA 2XR9A 1E3CP 3UO0A 3BDGB 4UPHA 5C66A 4ZG6A 1ELZA 3A52A 2IUCA 3UNYA 4LREA 5TJ3A 2GSOA 4GTWA 4LRDA 1KHJA 5INHA 3M7VA 2XGRA 5DLVA 5GRRA 1ELXA 4N7TA 3NKRA 2X98A 3UN3A 4CXKA 1ALJA 4GTXA 4KJDA 5LIAA 5GKPA 2ANHA 3BDFA 3MK0A 3WAVA 3WAWA 4CXUA 1ALIA 3OWVA 4GTYA 2W5WA 1AUKA 3NKOA 4UPIA 2GSNA 1ELYA 3UN2A 3M8YA 1KHNA 1O98A 5EGEA 5L0KA 2D1GA 1SMNA 4NWXA 4GTZA 4LR9A 1SHNA 4ZG7A 1AJDA 1N2KA 5EGHA 3MK1A 2W8DA 5DLWA 1HQAA 3TWZA 4FDJA 3TG0A 4LQYA 1EI6A 1KH9A 1EW9A 1URAA 4FDIA 3DPCA 4LRCA 2O3BA 3WAYA 3E2DA 1EJJA 1KH4A 1E33P 1QL0A 4MIVA 1Y7AA 3WAXA 1URBA 1E2SP 5HRTA 3NKNA 3S5BA 1ANIA 2XRGA 5L0EA 1KHKA 5GOVA 4KAYA 2VQRA 3LXQA 3SZZA 5GKCA 1O99A 1FSUA 4KJGA 4LR2A 2ZKTA 1Y6VA 3NKQA 3DYCA 5K4PA 1HJKA 3MK2A 4MHXA 4UPKA 2W5QA 5KXAA 1AJCA 2W8SA 1ED9A 2RH6A 5LRNA 4LR7A 3T00A 5LRMA 2W5VA 1KH5A 4CYSA 4TN0A 3IGYB 2W5SA 4QN0A 4NWJA 1ALKA 2W5TA 1ED8A 4ZG9A 5AJ9A 3SZYA 1EQJA 3TX0A 1K7HA 5IJSA
chains in the Genus database with same CATH topology
3T02A 3M8WA 4CYRA 1QAEA 4UOPA 5LQQA 4E3YA 4KAVA 1G8TA 3B5QA 4CXSA 1KH7A 5L0BA 2XH3A 4A1NA 1ZM8A 2IFYA 3OT9A 4UPLA 3IDDA 3Q3QA 4QAXA 1EW8A 1E1ZP 3BDGA 3NKPA 4KM4A 1P49A 5IJQA 1ALHA 4MY4A 3NKMA 4UORA 4LR8A 1ZEDA 1EW2A 1SHQA 4LRFA 2W5RA 3M8ZA 3ISMA 4ZGAA 3NVLA 1KHLA 3T01A 3KD8A 1ZEFA 3BDHA 4LRBA 3UN5A 4LRAA 4QGOA 2GLQA 4QH0A 1N2LA 4YR1A 2GA3A 2G9YA 2QZUA 2IUCB 1AJAA 4B56A 1AJBA 1HDHA 1ZEBA 3CMRA 1B8JA 3IGZB 4UOOA 1ANJA 5DLTA 3WBHA 3ED4A 2GSUA 2W5XA 2XR9A 1E3CP 3UO0A 3BDGB 4UPHA 5C66A 4ZG6A 1ELZA 3A52A 2IUCA 3UNYA 4LREA 5TJ3A 2GSOA 4GTWA 4LRDA 1KHJA 5INHA 3M7VA 2XGRA 5DLVA 5GRRA 1ELXA 4N7TA 3NKRA 2X98A 3UN3A 4CXKA 1ALJA 4GTXA 4KJDA 5LIAA 5GKPA 2ANHA 3BDFA 3MK0A 3WAVA 3WAWA 4CXUA 1ALIA 3OWVA 4GTYA 2W5WA 1AUKA 3NKOA 4UPIA 2GSNA 1ELYA 3UN2A 3M8YA 1KHNA 1O98A 5EGEA 5L0KA 2D1GA 1SMNA 4NWXA 4GTZA 4LR9A 1SHNA 4ZG7A 1AJDA 1N2KA 5EGHA 3MK1A 2W8DA 5DLWA 1HQAA 3TWZA 4FDJA 3TG0A 4LQYA 1EI6A 1KH9A 1EW9A 1URAA 4FDIA 3DPCA 4LRCA 2O3BA 3WAYA 3E2DA 1EJJA 1KH4A 1E33P 1QL0A 4MIVA 1Y7AA 3WAXA 1URBA 1E2SP 5HRTA 3NKNA 3S5BA 1ANIA 2XRGA 5L0EA 1KHKA 5GOVA 4KAYA 2VQRA 3LXQA 3SZZA 5GKCA 1O99A 1FSUA 4KJGA 4LR2A 2ZKTA 1Y6VA 3NKQA 3DYCA 5K4PA 1HJKA 3MK2A 4MHXA 4UPKA 2W5QA 5KXAA 1AJCA 2W8SA 1ED9A 2RH6A 5LRNA 4LR7A 3T00A 5LRMA 2W5VA 1KH5A 4CYSA 4TN0A 3IGYB 2W5SA 4QN0A 4NWJA 1ALKA 2W5TA 1ED8A 4ZG9A 5AJ9A 3SZYA 1EQJA 3TX0A 1K7HA 5IJSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T02 A;  3M8W A;  4CYR A;  1QAE A;  4UOP A;  5LQQ A;  4E3Y A;  4KAV A;  1G8T A;  3B5Q A;  4CXS A;  1KH7 A;  5L0B A;  2XH3 A;  4A1N A;  1ZM8 A;  2IFY A;  3OT9 A;  4UPL A;  3IDD A;  3Q3Q A;  4QAX A;  1EW8 A;  1E1Z P;  3BDG A;  3NKP A;  4KM4 A;  1P49 A;  5IJQ A;  1ALH A;  4MY4 A;  3NKM A;  4UOR A;  4LR8 A;  1ZED A;  1EW2 A;  1SHQ A;  4LRF A;  2W5R A;  3M8Z A;  3ISM A;  4ZGA A;  3NVL A;  1KHL A;  3T01 A;  3KD8 A;  1ZEF A;  3BDH A;  4LRB A;  3UN5 A;  4LRA A;  4QGO A;  2GLQ A;  4QH0 A;  1N2L A;  4YR1 A;  2GA3 A;  2G9Y A;  2QZU A;  2IUC B;  1AJA A;  4B56 A;  1AJB A;  1HDH A;  1ZEB A;  3CMR A;  1B8J A;  3IGZ B;  4UOO A;  1ANJ A;  5DLT A;  3WBH A;  3ED4 A;  2GSU A;  2W5X A;  2XR9 A;  1E3C P;  3UO0 A;  3BDG B;  4UPH A;  5C66 A;  4ZG6 A;  1ELZ A;  3A52 A;  2IUC A;  3UNY A;  4LRE A;  5TJ3 A;  2GSO A;  4GTW A;  4LRD A;  1KHJ A;  5INH A;  3M7V A;  2XGR A;  5DLV A;  5GRR A;  1ELX A;  4N7T A;  3NKR A;  2X98 A;  3UN3 A;  4CXK A;  1ALJ A;  4GTX A;  4KJD A;  5LIA A;  5GKP A;  2ANH A;  3BDF A;  3MK0 A;  3WAV A;  3WAW A;  4CXU A;  1ALI A;  3OWV A;  4GTY A;  2W5W A;  1AUK A;  3NKO A;  4UPI A;  2GSN A;  1ELY A;  3UN2 A;  3M8Y A;  1KHN A;  1O98 A;  5EGE A;  5L0K A;  2D1G A;  1SMN A;  4NWX A;  4GTZ A;  4LR9 A;  1SHN A;  4ZG7 A;  1AJD A;  1N2K A;  5EGH A;  3MK1 A;  2W8D A;  5DLW A;  1HQA A;  3TWZ A;  4FDJ A;  3TG0 A;  4LQY A;  1EI6 A;  1KH9 A;  1EW9 A;  1URA A;  4FDI A;  3DPC A;  4LRC A;  2O3B A;  3WAY A;  3E2D A;  1EJJ A;  1KH4 A;  1E33 P;  1QL0 A;  4MIV A;  1Y7A A;  3WAX A;  1URB A;  1E2S P;  5HRT A;  3NKN A;  3S5B A;  1ANI A;  2XRG A;  5L0E A;  1KHK A;  5GOV A;  4KAY A;  2VQR A;  3LXQ A;  3SZZ A;  5GKC A;  1O99 A;  1FSU A;  4KJG A;  4LR2 A;  2ZKT A;  1Y6V A;  3NKQ A;  3DYC A;  5K4P A;  1HJK A;  3MK2 A;  4MHX A;  4UPK A;  2W5Q A;  5KXA A;  1AJC A;  2W8S A;  1ED9 A;  2RH6 A;  5LRN A;  4LR7 A;  3T00 A;  5LRM A;  2W5V A;  1KH5 A;  4CYS A;  4TN0 A;  3IGY B;  2W5S A;  4QN0 A;  4NWJ A;  1ALK A;  2W5T A;  1ED8 A;  4ZG9 A;  5AJ9 A;  3SZY A;  1EQJ A;  3TX0 A;  1K7H A;  5IJS A; 
#chains in the Genus database with same CATH topology
 3T02 A;  3M8W A;  4CYR A;  1QAE A;  4UOP A;  5LQQ A;  4E3Y A;  4KAV A;  1G8T A;  3B5Q A;  4CXS A;  1KH7 A;  5L0B A;  2XH3 A;  4A1N A;  1ZM8 A;  2IFY A;  3OT9 A;  4UPL A;  3IDD A;  3Q3Q A;  4QAX A;  1EW8 A;  1E1Z P;  3BDG A;  3NKP A;  4KM4 A;  1P49 A;  5IJQ A;  1ALH A;  4MY4 A;  3NKM A;  4UOR A;  4LR8 A;  1ZED A;  1EW2 A;  1SHQ A;  4LRF A;  2W5R A;  3M8Z A;  3ISM A;  4ZGA A;  3NVL A;  1KHL A;  3T01 A;  3KD8 A;  1ZEF A;  3BDH A;  4LRB A;  3UN5 A;  4LRA A;  4QGO A;  2GLQ A;  4QH0 A;  1N2L A;  4YR1 A;  2GA3 A;  2G9Y A;  2QZU A;  2IUC B;  1AJA A;  4B56 A;  1AJB A;  1HDH A;  1ZEB A;  3CMR A;  1B8J A;  3IGZ B;  4UOO A;  1ANJ A;  5DLT A;  3WBH A;  3ED4 A;  2GSU A;  2W5X A;  2XR9 A;  1E3C P;  3UO0 A;  3BDG B;  4UPH A;  5C66 A;  4ZG6 A;  1ELZ A;  3A52 A;  2IUC A;  3UNY A;  4LRE A;  5TJ3 A;  2GSO A;  4GTW A;  4LRD A;  1KHJ A;  5INH A;  3M7V A;  2XGR A;  5DLV A;  5GRR A;  1ELX A;  4N7T A;  3NKR A;  2X98 A;  3UN3 A;  4CXK A;  1ALJ A;  4GTX A;  4KJD A;  5LIA A;  5GKP A;  2ANH A;  3BDF A;  3MK0 A;  3WAV A;  3WAW A;  4CXU A;  1ALI A;  3OWV A;  4GTY A;  2W5W A;  1AUK A;  3NKO A;  4UPI A;  2GSN A;  1ELY A;  3UN2 A;  3M8Y A;  1KHN A;  1O98 A;  5EGE A;  5L0K A;  2D1G A;  1SMN A;  4NWX A;  4GTZ A;  4LR9 A;  1SHN A;  4ZG7 A;  1AJD A;  1N2K A;  5EGH A;  3MK1 A;  2W8D A;  5DLW A;  1HQA A;  3TWZ A;  4FDJ A;  3TG0 A;  4LQY A;  1EI6 A;  1KH9 A;  1EW9 A;  1URA A;  4FDI A;  3DPC A;  4LRC A;  2O3B A;  3WAY A;  3E2D A;  1EJJ A;  1KH4 A;  1E33 P;  1QL0 A;  4MIV A;  1Y7A A;  3WAX A;  1URB A;  1E2S P;  5HRT A;  3NKN A;  3S5B A;  1ANI A;  2XRG A;  5L0E A;  1KHK A;  5GOV A;  4KAY A;  2VQR A;  3LXQ A;  3SZZ A;  5GKC A;  1O99 A;  1FSU A;  4KJG A;  4LR2 A;  2ZKT A;  1Y6V A;  3NKQ A;  3DYC A;  5K4P A;  1HJK A;  3MK2 A;  4MHX A;  4UPK A;  2W5Q A;  5KXA A;  1AJC A;  2W8S A;  1ED9 A;  2RH6 A;  5LRN A;  4LR7 A;  3T00 A;  5LRM A;  2W5V A;  1KH5 A;  4CYS A;  4TN0 A;  3IGY B;  2W5S A;  4QN0 A;  4NWJ A;  1ALK A;  2W5T A;  1ED8 A;  4ZG9 A;  5AJ9 A;  3SZY A;  1EQJ A;  3TX0 A;  1K7H A;  5IJS A; 
#chains in the Genus database with same CATH homology
 3T02 A;  3M8W A;  4CYR A;  1QAE A;  4UOP A;  5LQQ A;  4E3Y A;  4KAV A;  1G8T A;  3B5Q A;  4CXS A;  1KH7 A;  5L0B A;  2XH3 A;  4A1N A;  1ZM8 A;  2IFY A;  3OT9 A;  4UPL A;  3IDD A;  3Q3Q A;  4QAX A;  1EW8 A;  1E1Z P;  3BDG A;  3NKP A;  4KM4 A;  1P49 A;  5IJQ A;  1ALH A;  4MY4 A;  3NKM A;  4UOR A;  4LR8 A;  1ZED A;  1EW2 A;  1SHQ A;  4LRF A;  2W5R A;  3M8Z A;  3ISM A;  4ZGA A;  3NVL A;  1KHL A;  3T01 A;  3KD8 A;  1ZEF A;  3BDH A;  4LRB A;  3UN5 A;  4LRA A;  4QGO A;  2GLQ A;  4QH0 A;  1N2L A;  4YR1 A;  2GA3 A;  2G9Y A;  2QZU A;  2IUC B;  1AJA A;  4B56 A;  1AJB A;  1HDH A;  1ZEB A;  3CMR A;  1B8J A;  3IGZ B;  4UOO A;  1ANJ A;  5DLT A;  3WBH A;  3ED4 A;  2GSU A;  2W5X A;  2XR9 A;  1E3C P;  3UO0 A;  3BDG B;  4UPH A;  5C66 A;  4ZG6 A;  1ELZ A;  3A52 A;  2IUC A;  3UNY A;  4LRE A;  5TJ3 A;  2GSO A;  4GTW A;  4LRD A;  1KHJ A;  5INH A;  3M7V A;  2XGR A;  5DLV A;  5GRR A;  1ELX A;  4N7T A;  3NKR A;  2X98 A;  3UN3 A;  4CXK A;  1ALJ A;  4GTX A;  4KJD A;  5LIA A;  5GKP A;  2ANH A;  3BDF A;  3MK0 A;  3WAV A;  3WAW A;  4CXU A;  1ALI A;  3OWV A;  4GTY A;  2W5W A;  1AUK A;  3NKO A;  4UPI A;  2GSN A;  1ELY A;  3UN2 A;  3M8Y A;  1KHN A;  1O98 A;  5EGE A;  5L0K A;  2D1G A;  1SMN A;  4NWX A;  4GTZ A;  4LR9 A;  1SHN A;  4ZG7 A;  1AJD A;  1N2K A;  5EGH A;  3MK1 A;  2W8D A;  5DLW A;  1HQA A;  3TWZ A;  4FDJ A;  3TG0 A;  4LQY A;  1EI6 A;  1KH9 A;  1EW9 A;  1URA A;  4FDI A;  3DPC A;  4LRC A;  2O3B A;  3WAY A;  3E2D A;  1EJJ A;  1KH4 A;  1E33 P;  1QL0 A;  4MIV A;  1Y7A A;  3WAX A;  1URB A;  1E2S P;  5HRT A;  3NKN A;  3S5B A;  1ANI A;  2XRG A;  5L0E A;  1KHK A;  5GOV A;  4KAY A;  2VQR A;  3LXQ A;  3SZZ A;  5GKC A;  1O99 A;  1FSU A;  4KJG A;  4LR2 A;  2ZKT A;  1Y6V A;  3NKQ A;  3DYC A;  5K4P A;  1HJK A;  3MK2 A;  4MHX A;  4UPK A;  2W5Q A;  5KXA A;  1AJC A;  2W8S A;  1ED9 A;  2RH6 A;  5LRN A;  4LR7 A;  3T00 A;  5LRM A;  2W5V A;  1KH5 A;  4CYS A;  4TN0 A;  3IGY B;  2W5S A;  4QN0 A;  4NWJ A;  1ALK A;  2W5T A;  1ED8 A;  4ZG9 A;  5AJ9 A;  3SZY A;  1EQJ A;  3TX0 A;  1K7H A;  5IJS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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