3WAXA

Crystal structure of autotaxin in complex with 3boa
Total Genus 261
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
261
Knots found
sequence length
805
structure length
789
Chain Sequence
WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDLEELNHTKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
pubmed doi rcsb
source organism Mus musculus
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
total genus 261
structure length 789
sequence length 805
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2013-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3waxA04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3waxA03
1HDHA 1N2KA 3UNYA 1KH9A 4YR1A 2RH6A 4GTYA 2W5RA 5GOVA 4LRDA 4MIVA 2QZUA 2ANHA 2VQRA 2W5XA 3BDGA 3SZZA 4KJGA 3NKOA 1AJCA 3T00A 5TJ3A 1G8TA 1EW8A 2X98A 3NKRA 5LRNA 4ZGAA 1ZM8A 4FDJA 4A1NA 3UN3A 5GRRA 5IJQA 5L0EA 2XRGA 2W5VA 2O3BA 3Q3QA 3WAVA 2W5WA 4KJDA 1E33P 4GTXA 1QAEA 3MK1A 4ZG6A 1O99A 5DLWA 1KHJA 4LR7A 4LR8A 4CYSA 4UORA 4CXKA 3NKQA 1KH4A 2GSOA 4QAXA 3KD8A 4UPLA 3NKMA 2IFYA 1URAA 3NKNA 1N2LA 2D1GA 1ELZA 4LRCA 1HQAA 1ZEFA 5C66A 2W8DA 3BDFA 1ELXA 3B5QA 5GKPA 2W5QA 3NVLA 4TN0A 1P49A 1EJJA 3ED4A 4NWXA 1AJBA 3BDHA 4LRFA 4UPIA 1ALHA 2GSNA 4LREA 3UN5A 4MY4A 5KXAA 5L0BA 5LQQA 5IJSA 3MK2A 2XH3A 4GTZA 4LR9A 4CYRA 1EW2A 4UOOA 1FSUA 3TWZA 2GSUA 4KAYA 3TX0A 3UO0A 1ANJA 1ALKA 3M8YA 4KM4A 1Y6VA 3IGZB 3TG0A 4N7TA 3MK0A 3A52A 2W5SA 5EGHA 2W8SA 1E1ZP 4LR2A 5HRTA 4UPKA 2XR9A 4LQYA 4QGOA 4UOPA 4CXSA 3BDGB 1EW9A 5K4PA 1KH5A 3E2DA 3WBHA 3OWVA 5LRMA 1SHQA 1ALJA 2GLQA 5AJ9A 1ED9A 4ZG7A 5INHA 4B56A 1AUKA 2IUCA 4LRBA 4MHXA 3OT9A 3T01A 3IDDA 1ZEDA 5L0KA 5LIAA 3LXQA 4NWJA 5GKCA 1K7HA 1EI6A 3M7VA 5DLTA 3M8ZA 3DPCA 3ISMA 1EQJA 1ZEBA 1Y7AA 1QL0A 4GTWA 3IGYB 1SMNA 1O98A 1HJKA 2ZKTA 1ED8A 2W5TA 3DYCA 4E3YA 1ANIA 1SHNA 1ALIA 3S5BA 1E3CP 3M8WA 2GA3A 4LRAA 3WAXA 4KAVA 2G9YA 3CMRA 5EGEA 2IUCB 1B8JA 4QH0A 3WAWA 1ELYA 3T02A 3WAYA 1AJDA 3NKPA 4QN0A 1URBA 2XGRA 3SZYA 1KHKA 4FDIA 1AJAA 1KH7A 1KHLA 4UPHA 5DLVA 4CXUA 4ZG9A 3UN2A 1E2SP 1KHNA
chains in the Genus database with same CATH superfamily
1HDHA 1N2KA 3UNYA 1KH9A 4YR1A 2RH6A 4GTYA 2W5RA 5GOVA 4LRDA 4MIVA 2QZUA 2ANHA 2VQRA 2W5XA 3BDGA 3SZZA 4KJGA 3NKOA 1AJCA 3T00A 5TJ3A 1G8TA 1EW8A 2X98A 3NKRA 5LRNA 4ZGAA 1ZM8A 4FDJA 4A1NA 3UN3A 5GRRA 5IJQA 5L0EA 2XRGA 2W5VA 2O3BA 3Q3QA 3WAVA 2W5WA 4KJDA 1E33P 4GTXA 1QAEA 3MK1A 4ZG6A 1O99A 5DLWA 1KHJA 4LR7A 4LR8A 4CYSA 4UORA 4CXKA 3NKQA 1KH4A 2GSOA 4QAXA 3KD8A 4UPLA 3NKMA 2IFYA 1URAA 3NKNA 1N2LA 2D1GA 1ELZA 4LRCA 1HQAA 1ZEFA 5C66A 2W8DA 3BDFA 1ELXA 3B5QA 5GKPA 2W5QA 3NVLA 4TN0A 1P49A 1EJJA 3ED4A 4NWXA 1AJBA 3BDHA 4LRFA 4UPIA 1ALHA 2GSNA 4LREA 3UN5A 4MY4A 5KXAA 5L0BA 5LQQA 5IJSA 3MK2A 2XH3A 4GTZA 4LR9A 4CYRA 1EW2A 4UOOA 1FSUA 3TWZA 2GSUA 4KAYA 3TX0A 3UO0A 1ANJA 1ALKA 3M8YA 4KM4A 1Y6VA 3IGZB 3TG0A 4N7TA 3MK0A 3A52A 2W5SA 5EGHA 2W8SA 1E1ZP 4LR2A 5HRTA 4UPKA 2XR9A 4LQYA 4QGOA 4UOPA 4CXSA 3BDGB 1EW9A 5K4PA 1KH5A 3E2DA 3WBHA 3OWVA 5LRMA 1SHQA 1ALJA 2GLQA 5AJ9A 1ED9A 4ZG7A 5INHA 4B56A 1AUKA 2IUCA 4LRBA 4MHXA 3OT9A 3T01A 3IDDA 1ZEDA 5L0KA 5LIAA 3LXQA 4NWJA 5GKCA 1K7HA 1EI6A 3M7VA 5DLTA 3M8ZA 3DPCA 3ISMA 1EQJA 1ZEBA 1Y7AA 1QL0A 4GTWA 3IGYB 1SMNA 1O98A 1HJKA 2ZKTA 1ED8A 2W5TA 3DYCA 4E3YA 1ANIA 1SHNA 1ALIA 3S5BA 1E3CP 3M8WA 2GA3A 4LRAA 3WAXA 4KAVA 2G9YA 3CMRA 5EGEA 2IUCB 1B8JA 4QH0A 3WAWA 1ELYA 3T02A 3WAYA 1AJDA 3NKPA 4QN0A 1URBA 2XGRA 3SZYA 1KHKA 4FDIA 1AJAA 1KH7A 1KHLA 4UPHA 5DLVA 4CXUA 4ZG9A 3UN2A 1E2SP 1KHNA
chains in the Genus database with same CATH topology
1HDHA 1N2KA 3UNYA 1KH9A 4YR1A 2RH6A 4GTYA 2W5RA 5GOVA 4LRDA 4MIVA 2QZUA 2ANHA 2VQRA 2W5XA 3BDGA 3SZZA 4KJGA 3NKOA 1AJCA 3T00A 5TJ3A 1G8TA 1EW8A 2X98A 3NKRA 5LRNA 4ZGAA 1ZM8A 4FDJA 4A1NA 3UN3A 5GRRA 5IJQA 5L0EA 2XRGA 2W5VA 2O3BA 3Q3QA 3WAVA 2W5WA 4KJDA 1E33P 4GTXA 1QAEA 3MK1A 4ZG6A 1O99A 5DLWA 1KHJA 4LR7A 4LR8A 4CYSA 4UORA 4CXKA 3NKQA 1KH4A 2GSOA 4QAXA 3KD8A 4UPLA 3NKMA 2IFYA 1URAA 3NKNA 1N2LA 2D1GA 1ELZA 4LRCA 1HQAA 1ZEFA 5C66A 2W8DA 3BDFA 1ELXA 3B5QA 5GKPA 2W5QA 3NVLA 4TN0A 1P49A 1EJJA 3ED4A 4NWXA 1AJBA 3BDHA 4LRFA 4UPIA 1ALHA 2GSNA 4LREA 3UN5A 4MY4A 5KXAA 5L0BA 5LQQA 5IJSA 3MK2A 2XH3A 4GTZA 4LR9A 4CYRA 1EW2A 4UOOA 1FSUA 3TWZA 2GSUA 4KAYA 3TX0A 3UO0A 1ANJA 1ALKA 3M8YA 4KM4A 1Y6VA 3IGZB 3TG0A 4N7TA 3MK0A 3A52A 2W5SA 5EGHA 2W8SA 1E1ZP 4LR2A 5HRTA 4UPKA 2XR9A 4LQYA 4QGOA 4UOPA 4CXSA 3BDGB 1EW9A 5K4PA 1KH5A 3E2DA 3WBHA 3OWVA 5LRMA 1SHQA 1ALJA 2GLQA 5AJ9A 1ED9A 4ZG7A 5INHA 4B56A 1AUKA 2IUCA 4LRBA 4MHXA 3OT9A 3T01A 3IDDA 1ZEDA 5L0KA 5LIAA 3LXQA 4NWJA 5GKCA 1K7HA 1EI6A 3M7VA 5DLTA 3M8ZA 3DPCA 3ISMA 1EQJA 1ZEBA 1Y7AA 1QL0A 4GTWA 3IGYB 1SMNA 1O98A 1HJKA 2ZKTA 1ED8A 2W5TA 3DYCA 4E3YA 1ANIA 1SHNA 1ALIA 3S5BA 1E3CP 3M8WA 2GA3A 4LRAA 3WAXA 4KAVA 2G9YA 3CMRA 5EGEA 2IUCB 1B8JA 4QH0A 3WAWA 1ELYA 3T02A 3WAYA 1AJDA 3NKPA 4QN0A 1URBA 2XGRA 3SZYA 1KHKA 4FDIA 1AJAA 1KH7A 1KHLA 4UPHA 5DLVA 4CXUA 4ZG9A 3UN2A 1E2SP 1KHNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HDH A;  1N2K A;  3UNY A;  1KH9 A;  4YR1 A;  2RH6 A;  4GTY A;  2W5R A;  5GOV A;  4LRD A;  4MIV A;  2QZU A;  2ANH A;  2VQR A;  2W5X A;  3BDG A;  3SZZ A;  4KJG A;  3NKO A;  1AJC A;  3T00 A;  5TJ3 A;  1G8T A;  1EW8 A;  2X98 A;  3NKR A;  5LRN A;  4ZGA A;  1ZM8 A;  4FDJ A;  4A1N A;  3UN3 A;  5GRR A;  5IJQ A;  5L0E A;  2XRG A;  2W5V A;  2O3B A;  3Q3Q A;  3WAV A;  2W5W A;  4KJD A;  1E33 P;  4GTX A;  1QAE A;  3MK1 A;  4ZG6 A;  1O99 A;  5DLW A;  1KHJ A;  4LR7 A;  4LR8 A;  4CYS A;  4UOR A;  4CXK A;  3NKQ A;  1KH4 A;  2GSO A;  4QAX A;  3KD8 A;  4UPL A;  3NKM A;  2IFY A;  1URA A;  3NKN A;  1N2L A;  2D1G A;  1ELZ A;  4LRC A;  1HQA A;  1ZEF A;  5C66 A;  2W8D A;  3BDF A;  1ELX A;  3B5Q A;  5GKP A;  2W5Q A;  3NVL A;  4TN0 A;  1P49 A;  1EJJ A;  3ED4 A;  4NWX A;  1AJB A;  3BDH A;  4LRF A;  4UPI A;  1ALH A;  2GSN A;  4LRE A;  3UN5 A;  4MY4 A;  5KXA A;  5L0B A;  5LQQ A;  5IJS A;  3MK2 A;  2XH3 A;  4GTZ A;  4LR9 A;  4CYR A;  1EW2 A;  4UOO A;  1FSU A;  3TWZ A;  2GSU A;  4KAY A;  3TX0 A;  3UO0 A;  1ANJ A;  1ALK A;  3M8Y A;  4KM4 A;  1Y6V A;  3IGZ B;  3TG0 A;  4N7T A;  3MK0 A;  3A52 A;  2W5S A;  5EGH A;  2W8S A;  1E1Z P;  4LR2 A;  5HRT A;  4UPK A;  2XR9 A;  4LQY A;  4QGO A;  4UOP A;  4CXS A;  3BDG B;  1EW9 A;  5K4P A;  1KH5 A;  3E2D A;  3WBH A;  3OWV A;  5LRM A;  1SHQ A;  1ALJ A;  2GLQ A;  5AJ9 A;  1ED9 A;  4ZG7 A;  5INH A;  4B56 A;  1AUK A;  2IUC A;  4LRB A;  4MHX A;  3OT9 A;  3T01 A;  3IDD A;  1ZED A;  5L0K A;  5LIA A;  3LXQ A;  4NWJ A;  5GKC A;  1K7H A;  1EI6 A;  3M7V A;  5DLT A;  3M8Z A;  3DPC A;  3ISM A;  1EQJ A;  1ZEB A;  1Y7A A;  1QL0 A;  4GTW A;  3IGY B;  1SMN A;  1O98 A;  1HJK A;  2ZKT A;  1ED8 A;  2W5T A;  3DYC A;  4E3Y A;  1ANI A;  1SHN A;  1ALI A;  3S5B A;  1E3C P;  3M8W A;  2GA3 A;  4LRA A;  3WAX A;  4KAV A;  2G9Y A;  3CMR A;  5EGE A;  2IUC B;  1B8J A;  4QH0 A;  3WAW A;  1ELY A;  3T02 A;  3WAY A;  1AJD A;  3NKP A;  4QN0 A;  1URB A;  2XGR A;  3SZY A;  1KHK A;  4FDI A;  1AJA A;  1KH7 A;  1KHL A;  4UPH A;  5DLV A;  4CXU A;  4ZG9 A;  3UN2 A;  1E2S P;  1KHN A; 
#chains in the Genus database with same CATH topology
 1HDH A;  1N2K A;  3UNY A;  1KH9 A;  4YR1 A;  2RH6 A;  4GTY A;  2W5R A;  5GOV A;  4LRD A;  4MIV A;  2QZU A;  2ANH A;  2VQR A;  2W5X A;  3BDG A;  3SZZ A;  4KJG A;  3NKO A;  1AJC A;  3T00 A;  5TJ3 A;  1G8T A;  1EW8 A;  2X98 A;  3NKR A;  5LRN A;  4ZGA A;  1ZM8 A;  4FDJ A;  4A1N A;  3UN3 A;  5GRR A;  5IJQ A;  5L0E A;  2XRG A;  2W5V A;  2O3B A;  3Q3Q A;  3WAV A;  2W5W A;  4KJD A;  1E33 P;  4GTX A;  1QAE A;  3MK1 A;  4ZG6 A;  1O99 A;  5DLW A;  1KHJ A;  4LR7 A;  4LR8 A;  4CYS A;  4UOR A;  4CXK A;  3NKQ A;  1KH4 A;  2GSO A;  4QAX A;  3KD8 A;  4UPL A;  3NKM A;  2IFY A;  1URA A;  3NKN A;  1N2L A;  2D1G A;  1ELZ A;  4LRC A;  1HQA A;  1ZEF A;  5C66 A;  2W8D A;  3BDF A;  1ELX A;  3B5Q A;  5GKP A;  2W5Q A;  3NVL A;  4TN0 A;  1P49 A;  1EJJ A;  3ED4 A;  4NWX A;  1AJB A;  3BDH A;  4LRF A;  4UPI A;  1ALH A;  2GSN A;  4LRE A;  3UN5 A;  4MY4 A;  5KXA A;  5L0B A;  5LQQ A;  5IJS A;  3MK2 A;  2XH3 A;  4GTZ A;  4LR9 A;  4CYR A;  1EW2 A;  4UOO A;  1FSU A;  3TWZ A;  2GSU A;  4KAY A;  3TX0 A;  3UO0 A;  1ANJ A;  1ALK A;  3M8Y A;  4KM4 A;  1Y6V A;  3IGZ B;  3TG0 A;  4N7T A;  3MK0 A;  3A52 A;  2W5S A;  5EGH A;  2W8S A;  1E1Z P;  4LR2 A;  5HRT A;  4UPK A;  2XR9 A;  4LQY A;  4QGO A;  4UOP A;  4CXS A;  3BDG B;  1EW9 A;  5K4P A;  1KH5 A;  3E2D A;  3WBH A;  3OWV A;  5LRM A;  1SHQ A;  1ALJ A;  2GLQ A;  5AJ9 A;  1ED9 A;  4ZG7 A;  5INH A;  4B56 A;  1AUK A;  2IUC A;  4LRB A;  4MHX A;  3OT9 A;  3T01 A;  3IDD A;  1ZED A;  5L0K A;  5LIA A;  3LXQ A;  4NWJ A;  5GKC A;  1K7H A;  1EI6 A;  3M7V A;  5DLT A;  3M8Z A;  3DPC A;  3ISM A;  1EQJ A;  1ZEB A;  1Y7A A;  1QL0 A;  4GTW A;  3IGY B;  1SMN A;  1O98 A;  1HJK A;  2ZKT A;  1ED8 A;  2W5T A;  3DYC A;  4E3Y A;  1ANI A;  1SHN A;  1ALI A;  3S5B A;  1E3C P;  3M8W A;  2GA3 A;  4LRA A;  3WAX A;  4KAV A;  2G9Y A;  3CMR A;  5EGE A;  2IUC B;  1B8J A;  4QH0 A;  3WAW A;  1ELY A;  3T02 A;  3WAY A;  1AJD A;  3NKP A;  4QN0 A;  1URB A;  2XGR A;  3SZY A;  1KHK A;  4FDI A;  1AJA A;  1KH7 A;  1KHL A;  4UPH A;  5DLV A;  4CXU A;  4ZG9 A;  3UN2 A;  1E2S P;  1KHN A; 
#chains in the Genus database with same CATH homology
 1HDH A;  1N2K A;  3UNY A;  1KH9 A;  4YR1 A;  2RH6 A;  4GTY A;  2W5R A;  5GOV A;  4LRD A;  4MIV A;  2QZU A;  2ANH A;  2VQR A;  2W5X A;  3BDG A;  3SZZ A;  4KJG A;  3NKO A;  1AJC A;  3T00 A;  5TJ3 A;  1G8T A;  1EW8 A;  2X98 A;  3NKR A;  5LRN A;  4ZGA A;  1ZM8 A;  4FDJ A;  4A1N A;  3UN3 A;  5GRR A;  5IJQ A;  5L0E A;  2XRG A;  2W5V A;  2O3B A;  3Q3Q A;  3WAV A;  2W5W A;  4KJD A;  1E33 P;  4GTX A;  1QAE A;  3MK1 A;  4ZG6 A;  1O99 A;  5DLW A;  1KHJ A;  4LR7 A;  4LR8 A;  4CYS A;  4UOR A;  4CXK A;  3NKQ A;  1KH4 A;  2GSO A;  4QAX A;  3KD8 A;  4UPL A;  3NKM A;  2IFY A;  1URA A;  3NKN A;  1N2L A;  2D1G A;  1ELZ A;  4LRC A;  1HQA A;  1ZEF A;  5C66 A;  2W8D A;  3BDF A;  1ELX A;  3B5Q A;  5GKP A;  2W5Q A;  3NVL A;  4TN0 A;  1P49 A;  1EJJ A;  3ED4 A;  4NWX A;  1AJB A;  3BDH A;  4LRF A;  4UPI A;  1ALH A;  2GSN A;  4LRE A;  3UN5 A;  4MY4 A;  5KXA A;  5L0B A;  5LQQ A;  5IJS A;  3MK2 A;  2XH3 A;  4GTZ A;  4LR9 A;  4CYR A;  1EW2 A;  4UOO A;  1FSU A;  3TWZ A;  2GSU A;  4KAY A;  3TX0 A;  3UO0 A;  1ANJ A;  1ALK A;  3M8Y A;  4KM4 A;  1Y6V A;  3IGZ B;  3TG0 A;  4N7T A;  3MK0 A;  3A52 A;  2W5S A;  5EGH A;  2W8S A;  1E1Z P;  4LR2 A;  5HRT A;  4UPK A;  2XR9 A;  4LQY A;  4QGO A;  4UOP A;  4CXS A;  3BDG B;  1EW9 A;  5K4P A;  1KH5 A;  3E2D A;  3WBH A;  3OWV A;  5LRM A;  1SHQ A;  1ALJ A;  2GLQ A;  5AJ9 A;  1ED9 A;  4ZG7 A;  5INH A;  4B56 A;  1AUK A;  2IUC A;  4LRB A;  4MHX A;  3OT9 A;  3T01 A;  3IDD A;  1ZED A;  5L0K A;  5LIA A;  3LXQ A;  4NWJ A;  5GKC A;  1K7H A;  1EI6 A;  3M7V A;  5DLT A;  3M8Z A;  3DPC A;  3ISM A;  1EQJ A;  1ZEB A;  1Y7A A;  1QL0 A;  4GTW A;  3IGY B;  1SMN A;  1O98 A;  1HJK A;  2ZKT A;  1ED8 A;  2W5T A;  3DYC A;  4E3Y A;  1ANI A;  1SHN A;  1ALI A;  3S5B A;  1E3C P;  3M8W A;  2GA3 A;  4LRA A;  3WAX A;  4KAV A;  2G9Y A;  3CMR A;  5EGE A;  2IUC B;  1B8J A;  4QH0 A;  3WAW A;  1ELY A;  3T02 A;  3WAY A;  1AJD A;  3NKP A;  4QN0 A;  1URB A;  2XGR A;  3SZY A;  1KHK A;  4FDI A;  1AJA A;  1KH7 A;  1KHL A;  4UPH A;  5DLV A;  4CXU A;  4ZG9 A;  3UN2 A;  1E2S P;  1KHN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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