3WCJA

The complex structure of hssqs wtih ligand,e5700
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
334
structure length
334
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Squalene synthase as a target for Chagas disease therapeutics.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 139
structure length 334
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wcjA00
4KQUA 5IK6A 5ILIA 4LLSA 3P8LA 3G4DA 1YYTA 4NG6A 4KPDA 2AZLA 3APZA 4KVWA 3N0FA 5DJRF 5IK0A 3LGZB 2F89F 5IKHA 2J1OA 3AE0A 1V4HA 3Q2ZA 3Q2QA 5IVGA 3OABB 4KWDA 4MC0A 1YHLA 1VG6A 3N3LF 4LPHF 3PYAA 5ERMA 4EA2A 4E9ZA 3ZOUA 1YYRA 4GAXA 2OGDA 3AQ0A 1EZFA 3KRPB 3V66A 4RYPA 4P0WA 1JFGA 2E8TA 4NUAA 5ILJA 3VJ8A 4F6XA 3V1VA 3BNXA 1VG3A 3WC9A 3ASXA 1RQJA 4JXNA 1V4JA 5C05A 3W7FA 4JZBA 5HN7A 1FPSA 2DH4A 3PKOA 3NRIA 4LOBA 2Z4XA 3P5RA 4QPFA 3LDWA 3S4JA 4GP2A 5IKAA 3KRFB 5B00A 5AELA 3LSNA 4LZ0A 4GP1A 4OGUA 2Z52A 3OACA 3Q30A 2E92A 1WL0A 3VJCA 2Z7IA 3WEJA 2FTZA 3KROB 4XQRF 1YJ4A 5EATA 2PS7A 4N1ZF 2ONGA 1PS1A 3N0GA 3S9VA 4LA6A 5HN9A 3PH7A 2AZJA 5DW7A 3LK5A 1N20A 2PS4A 4KVDA 3ZL6A 1HX9A 2J5CA 1V4IA 4DI5A 3EGTA 3Q1OA 2E8WA 1RQIA 3VJDA 4HD1A 1KIZA 5DIQF 1N21A 4EA0A 3N5JF 4WK5A 5AFXA 3KRCA 2J1PA 3N1WF 1N23A 4JZXA 3WEGA 1RTRA 3KB9A 3N5HF 4LA5A 1WL1A 1N22A 2PS8A 4DZWA 1N24A 3ZCDA 5IN8A 2Z50A 5HNAA 4DEMF 3LG5A 4JYXA 3P8RA 3TC1A 3ICNA 3QKCA 1JFAA 4RXCA 3LGKA 4LZ3A 3WJOA 2ZCQA 3WJNA 4NFIF 4LFGA 5I1UA 1HM4A 4KUXA 1UBXA 2ZCOA 3ACYA 4KFAA 3SDRA 3KRAB 5IMPA 3NF2A 1N1ZA 4RXEA 3ICZA 5E8HA 4H5EF 3WCBA 3ACWA 3G4FA 4KVYA 2E91A 4KK2A 2ZCSA 5A0KA 1N1BA 1YHMA 4FJQA 4Q23A 2F9KF 3QQVA 4DHDA 5B03A 4F6VA 5IK9A 5JV2F 5ILKA 3P41A 4RXDA 3M00A 3WCMA 1WMWA 4EA1A 3CKEA 3IBAA 4MC8A 5HN8A 5DHKA 2RAHA 5IMIA 3ZMCA 3WCDA 2Q9ZA 4KQSA 3MAVA 4KQ5A 4NKFA 3TFNA 4RXAA 2PS6A 4F62A 5JUZF 4LFVF 3VJ9A 2Z7HA 3N49F 5B0KA 5IL8A 3TFVA 4L2XF 3M02A 3KRFA 3NPKA 4KKMA 3EFQA 4DXJA 2F94F 3WEKA 5IL3A 2OA6A 5EAUA 1VG7A 4DWBA 3ZMBA 4RNQA 1DI1A 4LTZA 2OPMA 2EWGA 3KROA 1HXAA 2F92F 1HM7A 2FORA 4PVXF 3M9UA 3SAEA 1WL2A 2Z4ZA 5EASA 3WCGA 4LUUA 3P5PA 2H8OA 5E8KA 3LLWA 5DGNF 1YV5A 3KRCB 3WEHA 2ZEUA 4XQTF 2Z4YA 2VF6A 5EROA 3RBMA 3VJEA 3WEFA 5B0MA 2F7MF 5ILYA 5B0LA 3WCIA 4E1EA 3DYHA 3WE9A 1HXCA 4JXYA 3SDVA 4H5DF 3SDQA 3KBKA 2ZY1A 5JV1F 3IPIA 3OYRA 3RMGA 5AYPA 3CC9A 3TS7A 1VG2A 2E8UA 3WCHA 4LIXA 1YYUA 2E8XA 3LVSA 5B0IA 4MC3A 1KIYA 5IMNA 4LZCA 2E95A 3AQCB 3M0GA 3WCCA 3SDTA 3MZVA 4E9UA 3B7LA 3NPRA 5A0IA 2F8ZF 4JVJF 5A0JA 5KSXF 1WY0A 3TFPA 3ACXA 3OABA 2AEKA 2E94A 3LJIA 5CG6A 4OKMA 4OMHA 4KVIA 4N9UA 2E8VA 1ZW5A 2AETA 3KRAA 3V1XA 1YYSA 3ADZA 5DJVF 3N45F 3KRPA 5B01A 2Z78A 3DYFA 5DGMF 3SDUA 4KPJA 1VG4A 4OKZA 3N1VF 3OACB 1DGPA 2E90A 2ONHA 5E8LA 5DJPF 2ZEVA 4H5CF 1HXGA 4LXWA 4LPGF 3WCAA 3LEEA 2Q9YA 3LZ9A 4LTVA 3AQBB 3ICKA 3LMDA 2ZCRA 5B0JA 4DWGA 2Z4VA 1UBVA 2OPNA 5JV0F 5DHIA 2E93A 3N6KF 3RYWA 3ICMA 2Q58A 5H9DA 4P0VA 5JA0F 1V4EA 5ILZA 3WCLA 5ILDA 3N46F 3RYEA 1UBYA 5IM1A 5ILHA 4UMJA 3WSAA 2AZKA 3WJKA 2F8CF 3VJBA 2PS5A 3WSBA 4XQSF 2I19A 3UCAA 2QISA 3M01A 3N3DA 4ZQ8A 5CG5A 4K10A 4FP4A 2P1CA 4QXSF 4GA3A 2O1OA 1YYQA 5DZ2A 2Z4WA 3WEIA 3ID0A 4LLTA 4PVYF 1YHKA 3LOMA 3PDEA 2Q80A 5ER8A 4NKEA 1WKZA 3PYBA 5DGSF 1WL3A 4LFEA 3DYGA 3EZ3A 5AHUB 5ERNA 5B02A 3VJAA 3WCJA 3CP6A 4OMGA 3WCEA 3WCFA 2AELA 1V4KA 2E4OA 4NFKF 4P0XA 4NFJF 1UBWA 3BNYA 1YQ7A
chains in the Genus database with same CATH superfamily
4KQUA 5IK6A 5ILIA 4LLSA 3P8LA 3G4DA 1YYTA 4NG6A 4KPDA 2AZLA 3APZA 4KVWA 3N0FA 5DJRF 5IK0A 3LGZB 2F89F 5IKHA 2J1OA 3AE0A 1V4HA 3Q2ZA 3Q2QA 5IVGA 3OABB 4KWDA 4MC0A 1YHLA 1VG6A 3N3LF 4LPHF 3PYAA 5ERMA 4EA2A 4E9ZA 3ZOUA 1YYRA 4GAXA 2OGDA 3AQ0A 1EZFA 3KRPB 3V66A 4RYPA 4P0WA 1JFGA 2E8TA 4NUAA 5ILJA 3VJ8A 4F6XA 3V1VA 3BNXA 1VG3A 3WC9A 3ASXA 1RQJA 4JXNA 1V4JA 5C05A 3W7FA 4JZBA 5HN7A 1FPSA 2DH4A 3PKOA 3NRIA 4LOBA 2Z4XA 3P5RA 4QPFA 3LDWA 3S4JA 4GP2A 5IKAA 3KRFB 5B00A 5AELA 3LSNA 4LZ0A 4GP1A 4OGUA 2Z52A 3OACA 3Q30A 2E92A 1WL0A 3VJCA 2Z7IA 3WEJA 2FTZA 3KROB 4XQRF 1YJ4A 5EATA 2PS7A 4N1ZF 2ONGA 1PS1A 3N0GA 3S9VA 4LA6A 5HN9A 3PH7A 2AZJA 5DW7A 3LK5A 1N20A 2PS4A 4KVDA 3ZL6A 1HX9A 2J5CA 1V4IA 4DI5A 3EGTA 3Q1OA 2E8WA 1RQIA 3VJDA 4HD1A 1KIZA 5DIQF 1N21A 4EA0A 3N5JF 4WK5A 5AFXA 3KRCA 2J1PA 3N1WF 1N23A 4JZXA 3WEGA 1RTRA 3KB9A 3N5HF 4LA5A 1WL1A 1N22A 2PS8A 4DZWA 1N24A 3ZCDA 5IN8A 2Z50A 5HNAA 4DEMF 3LG5A 4JYXA 3P8RA 3TC1A 3ICNA 3QKCA 1JFAA 4RXCA 3LGKA 4LZ3A 3WJOA 2ZCQA 3WJNA 4NFIF 4LFGA 5I1UA 1HM4A 4KUXA 1UBXA 2ZCOA 3ACYA 4KFAA 3SDRA 3KRAB 5IMPA 3NF2A 1N1ZA 4RXEA 3ICZA 5E8HA 4H5EF 3WCBA 3ACWA 3G4FA 4KVYA 2E91A 4KK2A 2ZCSA 5A0KA 1N1BA 1YHMA 4FJQA 4Q23A 2F9KF 3QQVA 4DHDA 5B03A 4F6VA 5IK9A 5JV2F 5ILKA 3P41A 4RXDA 3M00A 3WCMA 1WMWA 4EA1A 3CKEA 3IBAA 4MC8A 5HN8A 5DHKA 2RAHA 5IMIA 3ZMCA 3WCDA 2Q9ZA 4KQSA 3MAVA 4KQ5A 4NKFA 3TFNA 4RXAA 2PS6A 4F62A 5JUZF 4LFVF 3VJ9A 2Z7HA 3N49F 5B0KA 5IL8A 3TFVA 4L2XF 3M02A 3KRFA 3NPKA 4KKMA 3EFQA 4DXJA 2F94F 3WEKA 5IL3A 2OA6A 5EAUA 1VG7A 4DWBA 3ZMBA 4RNQA 1DI1A 4LTZA 2OPMA 2EWGA 3KROA 1HXAA 2F92F 1HM7A 2FORA 4PVXF 3M9UA 3SAEA 1WL2A 2Z4ZA 5EASA 3WCGA 4LUUA 3P5PA 2H8OA 5E8KA 3LLWA 5DGNF 1YV5A 3KRCB 3WEHA 2ZEUA 4XQTF 2Z4YA 2VF6A 5EROA 3RBMA 3VJEA 3WEFA 5B0MA 2F7MF 5ILYA 5B0LA 3WCIA 4E1EA 3DYHA 3WE9A 1HXCA 4JXYA 3SDVA 4H5DF 3SDQA 3KBKA 2ZY1A 5JV1F 3IPIA 3OYRA 3RMGA 5AYPA 3CC9A 3TS7A 1VG2A 2E8UA 3WCHA 4LIXA 1YYUA 2E8XA 3LVSA 5B0IA 4MC3A 1KIYA 5IMNA 4LZCA 2E95A 3AQCB 3M0GA 3WCCA 3SDTA 3MZVA 4E9UA 3B7LA 3NPRA 5A0IA 2F8ZF 4JVJF 5A0JA 5KSXF 1WY0A 3TFPA 3ACXA 3OABA 2AEKA 2E94A 3LJIA 5CG6A 4OKMA 4OMHA 4KVIA 4N9UA 2E8VA 1ZW5A 2AETA 3KRAA 3V1XA 1YYSA 3ADZA 5DJVF 3N45F 3KRPA 5B01A 2Z78A 3DYFA 5DGMF 3SDUA 4KPJA 1VG4A 4OKZA 3N1VF 3OACB 1DGPA 2E90A 2ONHA 5E8LA 5DJPF 2ZEVA 4H5CF 1HXGA 4LXWA 4LPGF 3WCAA 3LEEA 2Q9YA 3LZ9A 4LTVA 3AQBB 3ICKA 3LMDA 2ZCRA 5B0JA 4DWGA 2Z4VA 1UBVA 2OPNA 5JV0F 5DHIA 2E93A 3N6KF 3RYWA 3ICMA 2Q58A 5H9DA 4P0VA 5JA0F 1V4EA 5ILZA 3WCLA 5ILDA 3N46F 3RYEA 1UBYA 5IM1A 5ILHA 4UMJA 3WSAA 2AZKA 3WJKA 2F8CF 3VJBA 2PS5A 3WSBA 4XQSF 2I19A 3UCAA 2QISA 3M01A 3N3DA 4ZQ8A 5CG5A 4K10A 4FP4A 2P1CA 4QXSF 4GA3A 2O1OA 1YYQA 5DZ2A 2Z4WA 3WEIA 3ID0A 4LLTA 4PVYF 1YHKA 3LOMA 3PDEA 2Q80A 5ER8A 4NKEA 1WKZA 3PYBA 5DGSF 1WL3A 4LFEA 3DYGA 3EZ3A 5AHUB 5ERNA 5B02A 3VJAA 3WCJA 3CP6A 4OMGA 3WCEA 3WCFA 2AELA 1V4KA 2E4OA 4NFKF 4P0XA 4NFJF 1UBWA 3BNYA 1YQ7A
chains in the Genus database with same CATH topology
4KQUA 5IK6A 5ILIA 4LLSA 3P8LA 3G4DA 1YYTA 4NG6A 4KPDA 2AZLA 3APZA 4KVWA 3N0FA 5DJRF 5IK0A 3LGZB 2F89F 5IKHA 2J1OA 3AE0A 1V4HA 3Q2ZA 3Q2QA 5IVGA 3OABB 4KWDA 4MC0A 1YHLA 1VG6A 3N3LF 4LPHF 3PYAA 5ERMA 4EA2A 4E9ZA 3ZOUA 1YYRA 4GAXA 2OGDA 3AQ0A 1EZFA 3KRPB 3V66A 4RYPA 4P0WA 1JFGA 2E8TA 4NUAA 5ILJA 3VJ8A 4F6XA 3V1VA 3BNXA 1VG3A 3WC9A 3ASXA 1RQJA 4JXNA 1V4JA 5C05A 3W7FA 4JZBA 5HN7A 1FPSA 2DH4A 3PKOA 3NRIA 4LOBA 2Z4XA 3P5RA 4QPFA 3LDWA 3S4JA 4GP2A 5IKAA 3KRFB 5B00A 5AELA 3LSNA 4LZ0A 4GP1A 4OGUA 2Z52A 3OACA 3Q30A 2E92A 1WL0A 3VJCA 2Z7IA 3WEJA 2FTZA 3KROB 4XQRF 1YJ4A 5EATA 2PS7A 4N1ZF 2ONGA 1PS1A 3N0GA 3S9VA 4LA6A 5HN9A 3PH7A 2AZJA 5DW7A 3LK5A 1N20A 2PS4A 4KVDA 3ZL6A 1HX9A 2J5CA 1V4IA 4DI5A 3EGTA 3Q1OA 2E8WA 1RQIA 3VJDA 4HD1A 1KIZA 5DIQF 1N21A 4EA0A 3N5JF 4WK5A 5AFXA 3KRCA 2J1PA 3N1WF 1N23A 4JZXA 3WEGA 1RTRA 3KB9A 3N5HF 4LA5A 1WL1A 1N22A 2PS8A 4DZWA 1N24A 3ZCDA 5IN8A 2Z50A 5HNAA 4DEMF 3LG5A 4JYXA 3P8RA 3TC1A 3ICNA 3QKCA 1JFAA 4RXCA 3LGKA 4LZ3A 3WJOA 2ZCQA 3WJNA 4NFIF 4LFGA 5I1UA 1HM4A 4KUXA 1UBXA 2ZCOA 3ACYA 4KFAA 3SDRA 3KRAB 5IMPA 3NF2A 1N1ZA 4RXEA 3ICZA 5E8HA 4H5EF 3WCBA 3ACWA 3G4FA 4KVYA 2E91A 4KK2A 2ZCSA 5A0KA 1N1BA 1YHMA 4FJQA 4Q23A 2F9KF 3QQVA 4DHDA 5B03A 4F6VA 5IK9A 5JV2F 5ILKA 3P41A 4RXDA 3M00A 3WCMA 1WMWA 4EA1A 3CKEA 3IBAA 4MC8A 5HN8A 5DHKA 2RAHA 5IMIA 3ZMCA 3WCDA 2Q9ZA 4KQSA 3MAVA 4KQ5A 4NKFA 3TFNA 4RXAA 2PS6A 4F62A 5JUZF 4LFVF 3VJ9A 2Z7HA 3N49F 5B0KA 5IL8A 3TFVA 4L2XF 3M02A 3KRFA 3NPKA 4KKMA 3EFQA 4DXJA 2F94F 3WEKA 5IL3A 2OA6A 5EAUA 1VG7A 4DWBA 3ZMBA 4RNQA 1DI1A 4LTZA 2OPMA 2EWGA 3KROA 1HXAA 2F92F 1HM7A 2FORA 4PVXF 3M9UA 3SAEA 1WL2A 2Z4ZA 5EASA 3WCGA 4LUUA 3P5PA 2H8OA 5E8KA 3LLWA 5DGNF 1YV5A 3KRCB 3WEHA 2ZEUA 4XQTF 2Z4YA 2VF6A 5EROA 3RBMA 3VJEA 3WEFA 5B0MA 2F7MF 5ILYA 5B0LA 3WCIA 4E1EA 3DYHA 3WE9A 1HXCA 4JXYA 3SDVA 4H5DF 3SDQA 3KBKA 2ZY1A 5JV1F 3IPIA 3OYRA 3RMGA 5AYPA 3CC9A 3TS7A 1VG2A 2E8UA 3WCHA 4LIXA 1YYUA 2E8XA 3LVSA 5B0IA 4MC3A 1KIYA 5IMNA 4LZCA 2E95A 3AQCB 3M0GA 3WCCA 3SDTA 3MZVA 4E9UA 3B7LA 3NPRA 5A0IA 2F8ZF 4JVJF 5A0JA 5KSXF 1WY0A 3TFPA 3ACXA 3OABA 2AEKA 2E94A 3LJIA 5CG6A 4OKMA 4OMHA 4KVIA 4N9UA 2E8VA 1ZW5A 2AETA 3KRAA 3V1XA 1YYSA 3ADZA 5DJVF 3N45F 3KRPA 5B01A 2Z78A 3DYFA 5DGMF 3SDUA 4KPJA 1VG4A 4OKZA 3N1VF 3OACB 1DGPA 2E90A 2ONHA 5E8LA 5DJPF 2ZEVA 4H5CF 1HXGA 4LXWA 4LPGF 3WCAA 3LEEA 2Q9YA 3LZ9A 4LTVA 3AQBB 3ICKA 3LMDA 2ZCRA 5B0JA 4DWGA 2Z4VA 1UBVA 2OPNA 5JV0F 5DHIA 2E93A 3N6KF 3RYWA 3ICMA 2Q58A 5H9DA 4P0VA 5JA0F 1V4EA 5ILZA 3WCLA 5ILDA 3N46F 3RYEA 1UBYA 5IM1A 5ILHA 4UMJA 3WSAA 2AZKA 3WJKA 2F8CF 3VJBA 2PS5A 3WSBA 4XQSF 2I19A 3UCAA 2QISA 3M01A 3N3DA 4ZQ8A 5CG5A 4K10A 4FP4A 2P1CA 4QXSF 4GA3A 2O1OA 1YYQA 5DZ2A 2Z4WA 3WEIA 3ID0A 4LLTA 4PVYF 1YHKA 3LOMA 3PDEA 2Q80A 5ER8A 4NKEA 1WKZA 3PYBA 5DGSF 1WL3A 4LFEA 3DYGA 3EZ3A 5AHUB 5ERNA 5B02A 3VJAA 3WCJA 3CP6A 4OMGA 3WCEA 3WCFA 2AELA 1V4KA 2E4OA 4NFKF 4P0XA 4NFJF 1UBWA 3BNYA 1YQ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KQU A;  5IK6 A;  5ILI A;  4LLS A;  3P8L A;  3G4D A;  1YYT A;  4NG6 A;  4KPD A;  2AZL A;  3APZ A;  4KVW A;  3N0F A;  5DJR F;  5IK0 A;  3LGZ B;  2F89 F;  5IKH A;  2J1O A;  3AE0 A;  1V4H A;  3Q2Z A;  3Q2Q A;  5IVG A;  3OAB B;  4KWD A;  4MC0 A;  1YHL A;  1VG6 A;  3N3L F;  4LPH F;  3PYA A;  5ERM A;  4EA2 A;  4E9Z A;  3ZOU A;  1YYR A;  4GAX A;  2OGD A;  3AQ0 A;  1EZF A;  3KRP B;  3V66 A;  4RYP A;  4P0W A;  1JFG A;  2E8T A;  4NUA A;  5ILJ A;  3VJ8 A;  4F6X A;  3V1V A;  3BNX A;  1VG3 A;  3WC9 A;  3ASX A;  1RQJ A;  4JXN A;  1V4J A;  5C05 A;  3W7F A;  4JZB A;  5HN7 A;  1FPS A;  2DH4 A;  3PKO A;  3NRI A;  4LOB A;  2Z4X A;  3P5R A;  4QPF A;  3LDW A;  3S4J A;  4GP2 A;  5IKA A;  3KRF B;  5B00 A;  5AEL A;  3LSN A;  4LZ0 A;  4GP1 A;  4OGU A;  2Z52 A;  3OAC A;  3Q30 A;  2E92 A;  1WL0 A;  3VJC A;  2Z7I A;  3WEJ A;  2FTZ A;  3KRO B;  4XQR F;  1YJ4 A;  5EAT A;  2PS7 A;  4N1Z F;  2ONG A;  1PS1 A;  3N0G A;  3S9V A;  4LA6 A;  5HN9 A;  3PH7 A;  2AZJ A;  5DW7 A;  3LK5 A;  1N20 A;  2PS4 A;  4KVD A;  3ZL6 A;  1HX9 A;  2J5C A;  1V4I A;  4DI5 A;  3EGT A;  3Q1O A;  2E8W A;  1RQI A;  3VJD A;  4HD1 A;  1KIZ A;  5DIQ F;  1N21 A;  4EA0 A;  3N5J F;  4WK5 A;  5AFX A;  3KRC A;  2J1P A;  3N1W F;  1N23 A;  4JZX A;  3WEG A;  1RTR A;  3KB9 A;  3N5H F;  4LA5 A;  1WL1 A;  1N22 A;  2PS8 A;  4DZW A;  1N24 A;  3ZCD A;  5IN8 A;  2Z50 A;  5HNA A;  4DEM F;  3LG5 A;  4JYX A;  3P8R A;  3TC1 A;  3ICN A;  3QKC A;  1JFA A;  4RXC A;  3LGK A;  4LZ3 A;  3WJO A;  2ZCQ A;  3WJN A;  4NFI F;  4LFG A;  5I1U A;  1HM4 A;  4KUX A;  1UBX A;  2ZCO A;  3ACY A;  4KFA A;  3SDR A;  3KRA B;  5IMP A;  3NF2 A;  1N1Z A;  4RXE A;  3ICZ A;  5E8H A;  4H5E F;  3WCB A;  3ACW A;  3G4F A;  4KVY A;  2E91 A;  4KK2 A;  2ZCS A;  5A0K A;  1N1B A;  1YHM A;  4FJQ A;  4Q23 A;  2F9K F;  3QQV A;  4DHD A;  5B03 A;  4F6V A;  5IK9 A;  5JV2 F;  5ILK A;  3P41 A;  4RXD A;  3M00 A;  3WCM A;  1WMW A;  4EA1 A;  3CKE A;  3IBA A;  4MC8 A;  5HN8 A;  5DHK A;  2RAH A;  5IMI A;  3ZMC A;  3WCD A;  2Q9Z A;  4KQS A;  3MAV A;  4KQ5 A;  4NKF A;  3TFN A;  4RXA A;  2PS6 A;  4F62 A;  5JUZ F;  4LFV F;  3VJ9 A;  2Z7H A;  3N49 F;  5B0K A;  5IL8 A;  3TFV A;  4L2X F;  3M02 A;  3KRF A;  3NPK A;  4KKM A;  3EFQ A;  4DXJ A;  2F94 F;  3WEK A;  5IL3 A;  2OA6 A;  5EAU A;  1VG7 A;  4DWB A;  3ZMB A;  4RNQ A;  1DI1 A;  4LTZ A;  2OPM A;  2EWG A;  3KRO A;  1HXA A;  2F92 F;  1HM7 A;  2FOR A;  4PVX F;  3M9U A;  3SAE A;  1WL2 A;  2Z4Z A;  5EAS A;  3WCG A;  4LUU A;  3P5P A;  2H8O A;  5E8K A;  3LLW A;  5DGN F;  1YV5 A;  3KRC B;  3WEH A;  2ZEU A;  4XQT F;  2Z4Y A;  2VF6 A;  5ERO A;  3RBM A;  3VJE A;  3WEF A;  5B0M A;  2F7M F;  5ILY A;  5B0L A;  3WCI A;  4E1E A;  3DYH A;  3WE9 A;  1HXC A;  4JXY A;  3SDV A;  4H5D F;  3SDQ A;  3KBK A;  2ZY1 A;  5JV1 F;  3IPI A;  3OYR A;  3RMG A;  5AYP A;  3CC9 A;  3TS7 A;  1VG2 A;  2E8U A;  3WCH A;  4LIX A;  1YYU A;  2E8X A;  3LVS A;  5B0I A;  4MC3 A;  1KIY A;  5IMN A;  4LZC A;  2E95 A;  3AQC B;  3M0G A;  3WCC A;  3SDT A;  3MZV A;  4E9U A;  3B7L A;  3NPR A;  5A0I A;  2F8Z F;  4JVJ F;  5A0J A;  5KSX F;  1WY0 A;  3TFP A;  3ACX A;  3OAB A;  2AEK A;  2E94 A;  3LJI A;  5CG6 A;  4OKM A;  4OMH A;  4KVI A;  4N9U A;  2E8V A;  1ZW5 A;  2AET A;  3KRA A;  3V1X A;  1YYS A;  3ADZ A;  5DJV F;  3N45 F;  3KRP A;  5B01 A;  2Z78 A;  3DYF A;  5DGM F;  3SDU A;  4KPJ A;  1VG4 A;  4OKZ A;  3N1V F;  3OAC B;  1DGP A;  2E90 A;  2ONH A;  5E8L A;  5DJP F;  2ZEV A;  4H5C F;  1HXG A;  4LXW A;  4LPG F;  3WCA A;  3LEE A;  2Q9Y A;  3LZ9 A;  4LTV A;  3AQB B;  3ICK A;  3LMD A;  2ZCR A;  5B0J A;  4DWG A;  2Z4V A;  1UBV A;  2OPN A;  5JV0 F;  5DHI A;  2E93 A;  3N6K F;  3RYW A;  3ICM A;  2Q58 A;  5H9D A;  4P0V A;  5JA0 F;  1V4E A;  5ILZ A;  3WCL A;  5ILD A;  3N46 F;  3RYE A;  1UBY A;  5IM1 A;  5ILH A;  4UMJ A;  3WSA A;  2AZK A;  3WJK A;  2F8C F;  3VJB A;  2PS5 A;  3WSB A;  4XQS F;  2I19 A;  3UCA A;  2QIS A;  3M01 A;  3N3D A;  4ZQ8 A;  5CG5 A;  4K10 A;  4FP4 A;  2P1C A;  4QXS F;  4GA3 A;  2O1O A;  1YYQ A;  5DZ2 A;  2Z4W A;  3WEI A;  3ID0 A;  4LLT A;  4PVY F;  1YHK A;  3LOM A;  3PDE A;  2Q80 A;  5ER8 A;  4NKE A;  1WKZ A;  3PYB A;  5DGS F;  1WL3 A;  4LFE A;  3DYG A;  3EZ3 A;  5AHU B;  5ERN A;  5B02 A;  3VJA A;  3WCJ A;  3CP6 A;  4OMG A;  3WCE A;  3WCF A;  2AEL A;  1V4K A;  2E4O A;  4NFK F;  4P0X A;  4NFJ F;  1UBW A;  3BNY A;  1YQ7 A; 
#chains in the Genus database with same CATH topology
 4KQU A;  5IK6 A;  5ILI A;  4LLS A;  3P8L A;  3G4D A;  1YYT A;  4NG6 A;  4KPD A;  2AZL A;  3APZ A;  4KVW A;  3N0F A;  5DJR F;  5IK0 A;  3LGZ B;  2F89 F;  5IKH A;  2J1O A;  3AE0 A;  1V4H A;  3Q2Z A;  3Q2Q A;  5IVG A;  3OAB B;  4KWD A;  4MC0 A;  1YHL A;  1VG6 A;  3N3L F;  4LPH F;  3PYA A;  5ERM A;  4EA2 A;  4E9Z A;  3ZOU A;  1YYR A;  4GAX A;  2OGD A;  3AQ0 A;  1EZF A;  3KRP B;  3V66 A;  4RYP A;  4P0W A;  1JFG A;  2E8T A;  4NUA A;  5ILJ A;  3VJ8 A;  4F6X A;  3V1V A;  3BNX A;  1VG3 A;  3WC9 A;  3ASX A;  1RQJ A;  4JXN A;  1V4J A;  5C05 A;  3W7F A;  4JZB A;  5HN7 A;  1FPS A;  2DH4 A;  3PKO A;  3NRI A;  4LOB A;  2Z4X A;  3P5R A;  4QPF A;  3LDW A;  3S4J A;  4GP2 A;  5IKA A;  3KRF B;  5B00 A;  5AEL A;  3LSN A;  4LZ0 A;  4GP1 A;  4OGU A;  2Z52 A;  3OAC A;  3Q30 A;  2E92 A;  1WL0 A;  3VJC A;  2Z7I A;  3WEJ A;  2FTZ A;  3KRO B;  4XQR F;  1YJ4 A;  5EAT A;  2PS7 A;  4N1Z F;  2ONG A;  1PS1 A;  3N0G A;  3S9V A;  4LA6 A;  5HN9 A;  3PH7 A;  2AZJ A;  5DW7 A;  3LK5 A;  1N20 A;  2PS4 A;  4KVD A;  3ZL6 A;  1HX9 A;  2J5C A;  1V4I A;  4DI5 A;  3EGT A;  3Q1O A;  2E8W A;  1RQI A;  3VJD A;  4HD1 A;  1KIZ A;  5DIQ F;  1N21 A;  4EA0 A;  3N5J F;  4WK5 A;  5AFX A;  3KRC A;  2J1P A;  3N1W F;  1N23 A;  4JZX A;  3WEG A;  1RTR A;  3KB9 A;  3N5H F;  4LA5 A;  1WL1 A;  1N22 A;  2PS8 A;  4DZW A;  1N24 A;  3ZCD A;  5IN8 A;  2Z50 A;  5HNA A;  4DEM F;  3LG5 A;  4JYX A;  3P8R A;  3TC1 A;  3ICN A;  3QKC A;  1JFA A;  4RXC A;  3LGK A;  4LZ3 A;  3WJO A;  2ZCQ A;  3WJN A;  4NFI F;  4LFG A;  5I1U A;  1HM4 A;  4KUX A;  1UBX A;  2ZCO A;  3ACY A;  4KFA A;  3SDR A;  3KRA B;  5IMP A;  3NF2 A;  1N1Z A;  4RXE A;  3ICZ A;  5E8H A;  4H5E F;  3WCB A;  3ACW A;  3G4F A;  4KVY A;  2E91 A;  4KK2 A;  2ZCS A;  5A0K A;  1N1B A;  1YHM A;  4FJQ A;  4Q23 A;  2F9K F;  3QQV A;  4DHD A;  5B03 A;  4F6V A;  5IK9 A;  5JV2 F;  5ILK A;  3P41 A;  4RXD A;  3M00 A;  3WCM A;  1WMW A;  4EA1 A;  3CKE A;  3IBA A;  4MC8 A;  5HN8 A;  5DHK A;  2RAH A;  5IMI A;  3ZMC A;  3WCD A;  2Q9Z A;  4KQS A;  3MAV A;  4KQ5 A;  4NKF A;  3TFN A;  4RXA A;  2PS6 A;  4F62 A;  5JUZ F;  4LFV F;  3VJ9 A;  2Z7H A;  3N49 F;  5B0K A;  5IL8 A;  3TFV A;  4L2X F;  3M02 A;  3KRF A;  3NPK A;  4KKM A;  3EFQ A;  4DXJ A;  2F94 F;  3WEK A;  5IL3 A;  2OA6 A;  5EAU A;  1VG7 A;  4DWB A;  3ZMB A;  4RNQ A;  1DI1 A;  4LTZ A;  2OPM A;  2EWG A;  3KRO A;  1HXA A;  2F92 F;  1HM7 A;  2FOR A;  4PVX F;  3M9U A;  3SAE A;  1WL2 A;  2Z4Z A;  5EAS A;  3WCG A;  4LUU A;  3P5P A;  2H8O A;  5E8K A;  3LLW A;  5DGN F;  1YV5 A;  3KRC B;  3WEH A;  2ZEU A;  4XQT F;  2Z4Y A;  2VF6 A;  5ERO A;  3RBM A;  3VJE A;  3WEF A;  5B0M A;  2F7M F;  5ILY A;  5B0L A;  3WCI A;  4E1E A;  3DYH A;  3WE9 A;  1HXC A;  4JXY A;  3SDV A;  4H5D F;  3SDQ A;  3KBK A;  2ZY1 A;  5JV1 F;  3IPI A;  3OYR A;  3RMG A;  5AYP A;  3CC9 A;  3TS7 A;  1VG2 A;  2E8U A;  3WCH A;  4LIX A;  1YYU A;  2E8X A;  3LVS A;  5B0I A;  4MC3 A;  1KIY A;  5IMN A;  4LZC A;  2E95 A;  3AQC B;  3M0G A;  3WCC A;  3SDT A;  3MZV A;  4E9U A;  3B7L A;  3NPR A;  5A0I A;  2F8Z F;  4JVJ F;  5A0J A;  5KSX F;  1WY0 A;  3TFP A;  3ACX A;  3OAB A;  2AEK A;  2E94 A;  3LJI A;  5CG6 A;  4OKM A;  4OMH A;  4KVI A;  4N9U A;  2E8V A;  1ZW5 A;  2AET A;  3KRA A;  3V1X A;  1YYS A;  3ADZ A;  5DJV F;  3N45 F;  3KRP A;  5B01 A;  2Z78 A;  3DYF A;  5DGM F;  3SDU A;  4KPJ A;  1VG4 A;  4OKZ A;  3N1V F;  3OAC B;  1DGP A;  2E90 A;  2ONH A;  5E8L A;  5DJP F;  2ZEV A;  4H5C F;  1HXG A;  4LXW A;  4LPG F;  3WCA A;  3LEE A;  2Q9Y A;  3LZ9 A;  4LTV A;  3AQB B;  3ICK A;  3LMD A;  2ZCR A;  5B0J A;  4DWG A;  2Z4V A;  1UBV A;  2OPN A;  5JV0 F;  5DHI A;  2E93 A;  3N6K F;  3RYW A;  3ICM A;  2Q58 A;  5H9D A;  4P0V A;  5JA0 F;  1V4E A;  5ILZ A;  3WCL A;  5ILD A;  3N46 F;  3RYE A;  1UBY A;  5IM1 A;  5ILH A;  4UMJ A;  3WSA A;  2AZK A;  3WJK A;  2F8C F;  3VJB A;  2PS5 A;  3WSB A;  4XQS F;  2I19 A;  3UCA A;  2QIS A;  3M01 A;  3N3D A;  4ZQ8 A;  5CG5 A;  4K10 A;  4FP4 A;  2P1C A;  4QXS F;  4GA3 A;  2O1O A;  1YYQ A;  5DZ2 A;  2Z4W A;  3WEI A;  3ID0 A;  4LLT A;  4PVY F;  1YHK A;  3LOM A;  3PDE A;  2Q80 A;  5ER8 A;  4NKE A;  1WKZ A;  3PYB A;  5DGS F;  1WL3 A;  4LFE A;  3DYG A;  3EZ3 A;  5AHU B;  5ERN A;  5B02 A;  3VJA A;  3WCJ A;  3CP6 A;  4OMG A;  3WCE A;  3WCF A;  2AEL A;  1V4K A;  2E4O A;  4NFK F;  4P0X A;  4NFJ F;  1UBW A;  3BNY A;  1YQ7 A; 
#chains in the Genus database with same CATH homology
 4KQU A;  5IK6 A;  5ILI A;  4LLS A;  3P8L A;  3G4D A;  1YYT A;  4NG6 A;  4KPD A;  2AZL A;  3APZ A;  4KVW A;  3N0F A;  5DJR F;  5IK0 A;  3LGZ B;  2F89 F;  5IKH A;  2J1O A;  3AE0 A;  1V4H A;  3Q2Z A;  3Q2Q A;  5IVG A;  3OAB B;  4KWD A;  4MC0 A;  1YHL A;  1VG6 A;  3N3L F;  4LPH F;  3PYA A;  5ERM A;  4EA2 A;  4E9Z A;  3ZOU A;  1YYR A;  4GAX A;  2OGD A;  3AQ0 A;  1EZF A;  3KRP B;  3V66 A;  4RYP A;  4P0W A;  1JFG A;  2E8T A;  4NUA A;  5ILJ A;  3VJ8 A;  4F6X A;  3V1V A;  3BNX A;  1VG3 A;  3WC9 A;  3ASX A;  1RQJ A;  4JXN A;  1V4J A;  5C05 A;  3W7F A;  4JZB A;  5HN7 A;  1FPS A;  2DH4 A;  3PKO A;  3NRI A;  4LOB A;  2Z4X A;  3P5R A;  4QPF A;  3LDW A;  3S4J A;  4GP2 A;  5IKA A;  3KRF B;  5B00 A;  5AEL A;  3LSN A;  4LZ0 A;  4GP1 A;  4OGU A;  2Z52 A;  3OAC A;  3Q30 A;  2E92 A;  1WL0 A;  3VJC A;  2Z7I A;  3WEJ A;  2FTZ A;  3KRO B;  4XQR F;  1YJ4 A;  5EAT A;  2PS7 A;  4N1Z F;  2ONG A;  1PS1 A;  3N0G A;  3S9V A;  4LA6 A;  5HN9 A;  3PH7 A;  2AZJ A;  5DW7 A;  3LK5 A;  1N20 A;  2PS4 A;  4KVD A;  3ZL6 A;  1HX9 A;  2J5C A;  1V4I A;  4DI5 A;  3EGT A;  3Q1O A;  2E8W A;  1RQI A;  3VJD A;  4HD1 A;  1KIZ A;  5DIQ F;  1N21 A;  4EA0 A;  3N5J F;  4WK5 A;  5AFX A;  3KRC A;  2J1P A;  3N1W F;  1N23 A;  4JZX A;  3WEG A;  1RTR A;  3KB9 A;  3N5H F;  4LA5 A;  1WL1 A;  1N22 A;  2PS8 A;  4DZW A;  1N24 A;  3ZCD A;  5IN8 A;  2Z50 A;  5HNA A;  4DEM F;  3LG5 A;  4JYX A;  3P8R A;  3TC1 A;  3ICN A;  3QKC A;  1JFA A;  4RXC A;  3LGK A;  4LZ3 A;  3WJO A;  2ZCQ A;  3WJN A;  4NFI F;  4LFG A;  5I1U A;  1HM4 A;  4KUX A;  1UBX A;  2ZCO A;  3ACY A;  4KFA A;  3SDR A;  3KRA B;  5IMP A;  3NF2 A;  1N1Z A;  4RXE A;  3ICZ A;  5E8H A;  4H5E F;  3WCB A;  3ACW A;  3G4F A;  4KVY A;  2E91 A;  4KK2 A;  2ZCS A;  5A0K A;  1N1B A;  1YHM A;  4FJQ A;  4Q23 A;  2F9K F;  3QQV A;  4DHD A;  5B03 A;  4F6V A;  5IK9 A;  5JV2 F;  5ILK A;  3P41 A;  4RXD A;  3M00 A;  3WCM A;  1WMW A;  4EA1 A;  3CKE A;  3IBA A;  4MC8 A;  5HN8 A;  5DHK A;  2RAH A;  5IMI A;  3ZMC A;  3WCD A;  2Q9Z A;  4KQS A;  3MAV A;  4KQ5 A;  4NKF A;  3TFN A;  4RXA A;  2PS6 A;  4F62 A;  5JUZ F;  4LFV F;  3VJ9 A;  2Z7H A;  3N49 F;  5B0K A;  5IL8 A;  3TFV A;  4L2X F;  3M02 A;  3KRF A;  3NPK A;  4KKM A;  3EFQ A;  4DXJ A;  2F94 F;  3WEK A;  5IL3 A;  2OA6 A;  5EAU A;  1VG7 A;  4DWB A;  3ZMB A;  4RNQ A;  1DI1 A;  4LTZ A;  2OPM A;  2EWG A;  3KRO A;  1HXA A;  2F92 F;  1HM7 A;  2FOR A;  4PVX F;  3M9U A;  3SAE A;  1WL2 A;  2Z4Z A;  5EAS A;  3WCG A;  4LUU A;  3P5P A;  2H8O A;  5E8K A;  3LLW A;  5DGN F;  1YV5 A;  3KRC B;  3WEH A;  2ZEU A;  4XQT F;  2Z4Y A;  2VF6 A;  5ERO A;  3RBM A;  3VJE A;  3WEF A;  5B0M A;  2F7M F;  5ILY A;  5B0L A;  3WCI A;  4E1E A;  3DYH A;  3WE9 A;  1HXC A;  4JXY A;  3SDV A;  4H5D F;  3SDQ A;  3KBK A;  2ZY1 A;  5JV1 F;  3IPI A;  3OYR A;  3RMG A;  5AYP A;  3CC9 A;  3TS7 A;  1VG2 A;  2E8U A;  3WCH A;  4LIX A;  1YYU A;  2E8X A;  3LVS A;  5B0I A;  4MC3 A;  1KIY A;  5IMN A;  4LZC A;  2E95 A;  3AQC B;  3M0G A;  3WCC A;  3SDT A;  3MZV A;  4E9U A;  3B7L A;  3NPR A;  5A0I A;  2F8Z F;  4JVJ F;  5A0J A;  5KSX F;  1WY0 A;  3TFP A;  3ACX A;  3OAB A;  2AEK A;  2E94 A;  3LJI A;  5CG6 A;  4OKM A;  4OMH A;  4KVI A;  4N9U A;  2E8V A;  1ZW5 A;  2AET A;  3KRA A;  3V1X A;  1YYS A;  3ADZ A;  5DJV F;  3N45 F;  3KRP A;  5B01 A;  2Z78 A;  3DYF A;  5DGM F;  3SDU A;  4KPJ A;  1VG4 A;  4OKZ A;  3N1V F;  3OAC B;  1DGP A;  2E90 A;  2ONH A;  5E8L A;  5DJP F;  2ZEV A;  4H5C F;  1HXG A;  4LXW A;  4LPG F;  3WCA A;  3LEE A;  2Q9Y A;  3LZ9 A;  4LTV A;  3AQB B;  3ICK A;  3LMD A;  2ZCR A;  5B0J A;  4DWG A;  2Z4V A;  1UBV A;  2OPN A;  5JV0 F;  5DHI A;  2E93 A;  3N6K F;  3RYW A;  3ICM A;  2Q58 A;  5H9D A;  4P0V A;  5JA0 F;  1V4E A;  5ILZ A;  3WCL A;  5ILD A;  3N46 F;  3RYE A;  1UBY A;  5IM1 A;  5ILH A;  4UMJ A;  3WSA A;  2AZK A;  3WJK A;  2F8C F;  3VJB A;  2PS5 A;  3WSB A;  4XQS F;  2I19 A;  3UCA A;  2QIS A;  3M01 A;  3N3D A;  4ZQ8 A;  5CG5 A;  4K10 A;  4FP4 A;  2P1C A;  4QXS F;  4GA3 A;  2O1O A;  1YYQ A;  5DZ2 A;  2Z4W A;  3WEI A;  3ID0 A;  4LLT A;  4PVY F;  1YHK A;  3LOM A;  3PDE A;  2Q80 A;  5ER8 A;  4NKE A;  1WKZ A;  3PYB A;  5DGS F;  1WL3 A;  4LFE A;  3DYG A;  3EZ3 A;  5AHU B;  5ERN A;  5B02 A;  3VJA A;  3WCJ A;  3CP6 A;  4OMG A;  3WCE A;  3WCF A;  2AEL A;  1V4K A;  2E4O A;  4NFK F;  4P0X A;  4NFJ F;  1UBW A;  3BNY A;  1YQ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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