3WDDA

Mutant n-terminal domain of mycobacterium tuberculosis clpc1, f2y, bound to cyclomarin a
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
147
structure length
147
Chain Sequence
MYERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Chaperone/antimicrobial protein
molecule keywords Probable ATP-dependent Clp protease ATP-binding subunit
publication title Structural basis of mycobacterial inhibition by cyclomarin A
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 59
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 2013-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 3wddA00
4HH5A 2Y1QA 1KSFX 4HH6A 1QVRA 1K6KA 3ZRJA 2Y1RA 4UQWA 1R6QA 1R6BX 5HBNA 4IRFA 3FESA 4IODA 3WDBA 3WDCA 1LZWB 3ZRIA 3WDDA 1MBVA 1R6CX 3WDEA 1KHYA 1MBUA 1R6OA 3PXGA 1MBXA 4Y0CA 4P15A 4Y0BA 5GUIA 1MG9B 3FH2A 2K77A
chains in the Genus database with same CATH superfamily
4HH5A 2Y1QA 1KSFX 4HH6A 1QVRA 1K6KA 3ZRJA 2Y1RA 4UQWA 1R6QA 1R6BX 5HBNA 4IRFA 3FESA 4IODA 3WDBA 3WDCA 1LZWB 3ZRIA 3WDDA 1MBVA 1R6CX 3WDEA 1KHYA 1MBUA 1R6OA 3PXGA 1MBXA 4Y0CA 4P15A 4Y0BA 5GUIA 1MG9B 3FH2A 2K77A
chains in the Genus database with same CATH topology
4HH5A 2Y1QA 1KSFX 4HH6A 1QVRA 1K6KA 3ZRJA 2Y1RA 4UQWA 1R6QA 1R6BX 5HBNA 4IRFA 3FESA 4IODA 3WDBA 3WDCA 1LZWB 3ZRIA 3WDDA 1MBVA 1R6CX 3WDEA 1KHYA 1MBUA 1R6OA 3PXGA 1MBXA 4Y0CA 4P15A 4Y0BA 5GUIA 1MG9B 3FH2A 2K77A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HH5 A;  2Y1Q A;  1KSF X;  4HH6 A;  1QVR A;  1K6K A;  3ZRJ A;  2Y1R A;  4UQW A;  1R6Q A;  1R6B X;  5HBN A;  4IRF A;  3FES A;  4IOD A;  3WDB A;  3WDC A;  1LZW B;  3ZRI A;  3WDD A;  1MBV A;  1R6C X;  3WDE A;  1KHY A;  1MBU A;  1R6O A;  3PXG A;  1MBX A;  4Y0C A;  4P15 A;  4Y0B A;  5GUI A;  1MG9 B;  3FH2 A;  2K77 A; 
#chains in the Genus database with same CATH topology
 4HH5 A;  2Y1Q A;  1KSF X;  4HH6 A;  1QVR A;  1K6K A;  3ZRJ A;  2Y1R A;  4UQW A;  1R6Q A;  1R6B X;  5HBN A;  4IRF A;  3FES A;  4IOD A;  3WDB A;  3WDC A;  1LZW B;  3ZRI A;  3WDD A;  1MBV A;  1R6C X;  3WDE A;  1KHY A;  1MBU A;  1R6O A;  3PXG A;  1MBX A;  4Y0C A;  4P15 A;  4Y0B A;  5GUI A;  1MG9 B;  3FH2 A;  2K77 A; 
#chains in the Genus database with same CATH homology
 4HH5 A;  2Y1Q A;  1KSF X;  4HH6 A;  1QVR A;  1K6K A;  3ZRJ A;  2Y1R A;  4UQW A;  1R6Q A;  1R6B X;  5HBN A;  4IRF A;  3FES A;  4IOD A;  3WDB A;  3WDC A;  1LZW B;  3ZRI A;  3WDD A;  1MBV A;  1R6C X;  3WDE A;  1KHY A;  1MBU A;  1R6O A;  3PXG A;  1MBX A;  4Y0C A;  4P15 A;  4Y0B A;  5GUI A;  1MG9 B;  3FH2 A;  2K77 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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