3WDEA

Mutant n-terminal domain of mycobacterium tuberculosis clpc1, f80y, bound to cyclomarin a
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
147
structure length
147
Chain Sequence
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPYTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Chaperone/antimicrobial protein
molecule keywords Probable ATP-dependent Clp protease ATP-binding subunit
publication title Structural basis of mycobacterial inhibition by cyclomarin A
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 60
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 2013-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 3wdeA00
3ZRJA 3WDCA 4UQWA 3FESA 1R6QA 1MBUA 4P15A 2Y1RA 4Y0BA 4IRFA 1QVRA 1KSFX 1MBXA 3WDBA 5HBNA 2Y1QA 4HH6A 1KHYA 1R6BX 3WDEA 4HH5A 1LZWB 4Y0CA 4IODA 3FH2A 3WDDA 5GUIA 1MG9B 1MBVA 3PXGA 1R6OA 1R6CX 1K6KA 2K77A 3ZRIA
chains in the Genus database with same CATH superfamily
3ZRJA 3WDCA 4UQWA 3FESA 1R6QA 1MBUA 4P15A 2Y1RA 4Y0BA 4IRFA 1QVRA 1KSFX 1MBXA 3WDBA 5HBNA 2Y1QA 4HH6A 1KHYA 1R6BX 3WDEA 4HH5A 1LZWB 4Y0CA 4IODA 3FH2A 3WDDA 5GUIA 1MG9B 1MBVA 3PXGA 1R6OA 1R6CX 1K6KA 2K77A 3ZRIA
chains in the Genus database with same CATH topology
3ZRJA 3WDCA 4UQWA 3FESA 1R6QA 1MBUA 4P15A 2Y1RA 4Y0BA 4IRFA 1QVRA 1KSFX 1MBXA 3WDBA 5HBNA 2Y1QA 4HH6A 1KHYA 1R6BX 3WDEA 4HH5A 1LZWB 4Y0CA 4IODA 3FH2A 3WDDA 5GUIA 1MG9B 1MBVA 3PXGA 1R6OA 1R6CX 1K6KA 2K77A 3ZRIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZRJ A;  3WDC A;  4UQW A;  3FES A;  1R6Q A;  1MBU A;  4P15 A;  2Y1R A;  4Y0B A;  4IRF A;  1QVR A;  1KSF X;  1MBX A;  3WDB A;  5HBN A;  2Y1Q A;  4HH6 A;  1KHY A;  1R6B X;  3WDE A;  4HH5 A;  1LZW B;  4Y0C A;  4IOD A;  3FH2 A;  3WDD A;  5GUI A;  1MG9 B;  1MBV A;  3PXG A;  1R6O A;  1R6C X;  1K6K A;  2K77 A;  3ZRI A; 
#chains in the Genus database with same CATH topology
 3ZRJ A;  3WDC A;  4UQW A;  3FES A;  1R6Q A;  1MBU A;  4P15 A;  2Y1R A;  4Y0B A;  4IRF A;  1QVR A;  1KSF X;  1MBX A;  3WDB A;  5HBN A;  2Y1Q A;  4HH6 A;  1KHY A;  1R6B X;  3WDE A;  4HH5 A;  1LZW B;  4Y0C A;  4IOD A;  3FH2 A;  3WDD A;  5GUI A;  1MG9 B;  1MBV A;  3PXG A;  1R6O A;  1R6C X;  1K6K A;  2K77 A;  3ZRI A; 
#chains in the Genus database with same CATH homology
 3ZRJ A;  3WDC A;  4UQW A;  3FES A;  1R6Q A;  1MBU A;  4P15 A;  2Y1R A;  4Y0B A;  4IRF A;  1QVR A;  1KSF X;  1MBX A;  3WDB A;  5HBN A;  2Y1Q A;  4HH6 A;  1KHY A;  1R6B X;  3WDE A;  4HH5 A;  1LZW B;  4Y0C A;  4IOD A;  3FH2 A;  3WDD A;  5GUI A;  1MG9 B;  1MBV A;  3PXG A;  1R6O A;  1R6C X;  1K6K A;  2K77 A;  3ZRI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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