3WEKA

Crystal structure of the human squalene synthase f288l mutant in complex with presqualene pyrophosphate
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
335
structure length
335
Chain Sequence
SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNLCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Squalene synthase
publication title Structural insights into the catalytic mechanism of human squalene synthase
doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 133
structure length 335
sequence length 335
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wekA00
2F92F 3DYFA 5ILJA 1KIZA 3TC1A 3WCMA 5DW7A 5IKAA 5DZ2A 3SDVA 5IMNA 5IK0A 4LIXA 5ILZA 3VJEA 4DXJA 5ILIA 1YHLA 5A0JA 3WCAA 3Q1OA 5AHUB 4DEMF 4E9ZA 4KVIA 3TS7A 3WJNA 1DGPA 5DIQF 5HN7A 3PYAA 1HM4A 3RYEA 3M01A 4LPGF 4MC0A 3RYWA 3LK5A 4LZ0A 4H5EF 4LXWA 2QISA 3KROA 3RMGA 1JFAA 2AZLA 3VJ8A 4RXEA 1V4JA 3P8LA 5IVGA 4EA1A 3P5PA 2AZJA 2PS7A 3WSBA 3LVSA 3UCAA 5B0KA 3P41A 2ZCQA 4KWDA 3QKCA 5IN8A 3WEJA 2EWGA 1N1ZA 5IKHA 1HXGA 4NFIF 2J1PA 3ACXA 3G4FA 3N3LF 4GA3A 3OABA 3V1XA 3WCEA 5DGNF 5DJPF 3SDQA 1YYRA 4WK5A 3WCLA 2Q80A 4JYXA 4XQRF 3AQBB 3TFVA 3N49F 1UBYA 1WKZA 2ONHA 5CG6A 1WL3A 2P1CA 1HX9A 1YYTA 4JZXA 3ICNA 4LOBA 2ONGA 5ER8A 3M0GA 4F6VA 4RXAA 5DJRF 5EROA 2Z4WA 4KQ5A 4LZ3A 3KRCA 5JV2F 3WCCA 3WJOA 1FPSA 1V4HA 3ASXA 3WCGA 1YYQA 4QPFA 3M02A 1RQIA 3ICZA 2F9KF 1WY0A 2OPMA 2FORA 3LJIA 4DI5A 2E8UA 3PYBA 5EAUA 2F7MF 3KRFA 3S9VA 2Z52A 3WSAA 3EGTA 3LGKA 4LFEA 3Q2ZA 4LFGA 4QXSF 3KBKA 3N46F 3ADZA 1V4EA 5DJVF 3M9UA 4RNQA 5I1UA 2Z4YA 3IPIA 2Z4XA 4H5DF 3N5HF 4NG6A 3KROB 5B02A 5ERMA 3N1VF 2E92A 3QQVA 4GP1A 3Q30A 4XQTF 3ZOUA 4OGUA 4MC8A 5HNAA 5B00A 3PKOA 2OPNA 2FTZA 3LGZB 5IK9A 5JUZF 3P8RA 4DWGA 3ID0A 4NFKF 2Z78A 1V4IA 5HN8A 3N0GA 4PVYF 5ILYA 1VG3A 2ZY1A 5E8HA 4KVYA 4JZBA 2ZEVA 1EZFA 3OABB 1N24A 5A0KA 1UBVA 2F94F 2E8VA 3VJDA 3PH7A 3APZA 2AELA 3KRPB 4LLTA 2Z7HA 3VJCA 4KK2A 2ZEUA 4LFVF 2Z50A 3NPRA 3NF2A 4KVWA 3N45F 4F6XA 4OMHA 4JXNA 4LZCA 4E9UA 3KRCB 4DWBA 4H5CF 4KPDA 5ILHA 1N23A 4OKMA 3LG5A 3WCFA 4MC3A 4RXCA 3ZCDA 4LUUA 5HN9A 3SDUA 3RBMA 2AETA 3PDEA 4KQUA 3KRFB 1YQ7A 3KRPA 4JVJF 2H8OA 2I19A 4ZQ8A 1DI1A 3VJAA 3NPKA 4KPJA 5A0IA 3LLWA 1RTRA 3BNXA 1HXCA 3AQCB 3ZMCA 1VG4A 5DGSF 3Q2QA 4LA5A 4FP4A 1UBWA 1UBXA 5ERNA 4EA0A 2E8WA 1YHMA 3TFNA 4KVDA 1VG7A 1N21A 4OMGA 3KRAA 5EASA 4N9UA 4DHDA 2Q9YA 1VG6A 3SDRA 3G4DA 3V66A 5DHKA 4OKZA 4KUXA 3WCHA 2F89F 2VF6A 3EFQA 3KB9A 1ZW5A 4KQSA 1YYUA 4P0VA 2E90A 4NKEA 4LLSA 5IL3A 2E8XA 4P0XA 3WJKA 5JA0F 3V1VA 3W7FA 1YHKA 3ACYA 3CP6A 5AELA 1PS1A 2ZCRA 2E8TA 2E4OA 5IL8A 3WCIA 3ACWA 4DZWA 5B0LA 3P5RA 2Z4VA 4KKMA 3S4JA 2PS8A 4KFAA 1WL2A 1HM7A 4XQSF 3WCJA 3AQ0A 4Q23A 5KSXF 3LEEA 4NKFA 2AEKA 4N1ZF 5IM1A 3MAVA 3LMDA 4L2XF 3NRIA 5EATA 3DYHA 5DHIA 2E93A 4LPHF 1JFGA 3N5JF 2O1OA 3LOMA 1N1BA 2OGDA 2E94A 3LZ9A 3WEIA 3WEFA 5JV0F 5AFXA 3ZL6A 3OACA 3CKEA 2Z7IA 4JXYA 3SAEA 1VG2A 4NFJF 1YJ4A 3N3DA 5CG5A 2J1OA 2PS5A 5B01A 5B0MA 3KRAB 5E8KA 2J5CA 4RYPA 4PVXF 1WL0A 4FJQA 3OYRA 4K10A 2PS6A 3N6KF 3SDTA 2Q9ZA 5ILDA 4LA6A 3IBAA 3DYGA 4LTZA 4GAXA 5E8LA 2E91A 4EA2A 4RXDA 1N20A 4LTVA 3WEHA 3ZMBA 3EZ3A 4P0WA 2F8CF 2E95A 3VJBA 3MZVA 2PS4A 3LDWA 3WC9A 3TFPA 5B0JA 3WEKA 3N0FA 5C05A 1HXAA 5DGMF 2DH4A 2ZCSA 3AE0A 2Z4ZA 4E1EA 3ICMA 2ZCOA 3VJ9A 1YYSA 4HD1A 5JV1F 3WCDA 2AZKA 3WE9A 5B03A 5H9DA 5ILKA 3B7LA 3WEGA 4GP2A 2RAHA 2Q58A 3ICKA 1RQJA 1WL1A 5AYPA 3BNYA 3LSNA 3M00A 2OA6A 3N1WF 4UMJA 5IMIA 3CC9A 1V4KA 1YV5A 1KIYA 3WCBA 5IK6A 5IMPA 1WMWA 3OACB 2F8ZF 4F62A 4NUAA 1N22A 5B0IA
chains in the Genus database with same CATH superfamily
2F92F 3DYFA 5ILJA 1KIZA 3TC1A 3WCMA 5DW7A 5IKAA 5DZ2A 3SDVA 5IMNA 5IK0A 4LIXA 5ILZA 3VJEA 4DXJA 5ILIA 1YHLA 5A0JA 3WCAA 3Q1OA 5AHUB 4DEMF 4E9ZA 4KVIA 3TS7A 3WJNA 1DGPA 5DIQF 5HN7A 3PYAA 1HM4A 3RYEA 3M01A 4LPGF 4MC0A 3RYWA 3LK5A 4LZ0A 4H5EF 4LXWA 2QISA 3KROA 3RMGA 1JFAA 2AZLA 3VJ8A 4RXEA 1V4JA 3P8LA 5IVGA 4EA1A 3P5PA 2AZJA 2PS7A 3WSBA 3LVSA 3UCAA 5B0KA 3P41A 2ZCQA 4KWDA 3QKCA 5IN8A 3WEJA 2EWGA 1N1ZA 5IKHA 1HXGA 4NFIF 2J1PA 3ACXA 3G4FA 3N3LF 4GA3A 3OABA 3V1XA 3WCEA 5DGNF 5DJPF 3SDQA 1YYRA 4WK5A 3WCLA 2Q80A 4JYXA 4XQRF 3AQBB 3TFVA 3N49F 1UBYA 1WKZA 2ONHA 5CG6A 1WL3A 2P1CA 1HX9A 1YYTA 4JZXA 3ICNA 4LOBA 2ONGA 5ER8A 3M0GA 4F6VA 4RXAA 5DJRF 5EROA 2Z4WA 4KQ5A 4LZ3A 3KRCA 5JV2F 3WCCA 3WJOA 1FPSA 1V4HA 3ASXA 3WCGA 1YYQA 4QPFA 3M02A 1RQIA 3ICZA 2F9KF 1WY0A 2OPMA 2FORA 3LJIA 4DI5A 2E8UA 3PYBA 5EAUA 2F7MF 3KRFA 3S9VA 2Z52A 3WSAA 3EGTA 3LGKA 4LFEA 3Q2ZA 4LFGA 4QXSF 3KBKA 3N46F 3ADZA 1V4EA 5DJVF 3M9UA 4RNQA 5I1UA 2Z4YA 3IPIA 2Z4XA 4H5DF 3N5HF 4NG6A 3KROB 5B02A 5ERMA 3N1VF 2E92A 3QQVA 4GP1A 3Q30A 4XQTF 3ZOUA 4OGUA 4MC8A 5HNAA 5B00A 3PKOA 2OPNA 2FTZA 3LGZB 5IK9A 5JUZF 3P8RA 4DWGA 3ID0A 4NFKF 2Z78A 1V4IA 5HN8A 3N0GA 4PVYF 5ILYA 1VG3A 2ZY1A 5E8HA 4KVYA 4JZBA 2ZEVA 1EZFA 3OABB 1N24A 5A0KA 1UBVA 2F94F 2E8VA 3VJDA 3PH7A 3APZA 2AELA 3KRPB 4LLTA 2Z7HA 3VJCA 4KK2A 2ZEUA 4LFVF 2Z50A 3NPRA 3NF2A 4KVWA 3N45F 4F6XA 4OMHA 4JXNA 4LZCA 4E9UA 3KRCB 4DWBA 4H5CF 4KPDA 5ILHA 1N23A 4OKMA 3LG5A 3WCFA 4MC3A 4RXCA 3ZCDA 4LUUA 5HN9A 3SDUA 3RBMA 2AETA 3PDEA 4KQUA 3KRFB 1YQ7A 3KRPA 4JVJF 2H8OA 2I19A 4ZQ8A 1DI1A 3VJAA 3NPKA 4KPJA 5A0IA 3LLWA 1RTRA 3BNXA 1HXCA 3AQCB 3ZMCA 1VG4A 5DGSF 3Q2QA 4LA5A 4FP4A 1UBWA 1UBXA 5ERNA 4EA0A 2E8WA 1YHMA 3TFNA 4KVDA 1VG7A 1N21A 4OMGA 3KRAA 5EASA 4N9UA 4DHDA 2Q9YA 1VG6A 3SDRA 3G4DA 3V66A 5DHKA 4OKZA 4KUXA 3WCHA 2F89F 2VF6A 3EFQA 3KB9A 1ZW5A 4KQSA 1YYUA 4P0VA 2E90A 4NKEA 4LLSA 5IL3A 2E8XA 4P0XA 3WJKA 5JA0F 3V1VA 3W7FA 1YHKA 3ACYA 3CP6A 5AELA 1PS1A 2ZCRA 2E8TA 2E4OA 5IL8A 3WCIA 3ACWA 4DZWA 5B0LA 3P5RA 2Z4VA 4KKMA 3S4JA 2PS8A 4KFAA 1WL2A 1HM7A 4XQSF 3WCJA 3AQ0A 4Q23A 5KSXF 3LEEA 4NKFA 2AEKA 4N1ZF 5IM1A 3MAVA 3LMDA 4L2XF 3NRIA 5EATA 3DYHA 5DHIA 2E93A 4LPHF 1JFGA 3N5JF 2O1OA 3LOMA 1N1BA 2OGDA 2E94A 3LZ9A 3WEIA 3WEFA 5JV0F 5AFXA 3ZL6A 3OACA 3CKEA 2Z7IA 4JXYA 3SAEA 1VG2A 4NFJF 1YJ4A 3N3DA 5CG5A 2J1OA 2PS5A 5B01A 5B0MA 3KRAB 5E8KA 2J5CA 4RYPA 4PVXF 1WL0A 4FJQA 3OYRA 4K10A 2PS6A 3N6KF 3SDTA 2Q9ZA 5ILDA 4LA6A 3IBAA 3DYGA 4LTZA 4GAXA 5E8LA 2E91A 4EA2A 4RXDA 1N20A 4LTVA 3WEHA 3ZMBA 3EZ3A 4P0WA 2F8CF 2E95A 3VJBA 3MZVA 2PS4A 3LDWA 3WC9A 3TFPA 5B0JA 3WEKA 3N0FA 5C05A 1HXAA 5DGMF 2DH4A 2ZCSA 3AE0A 2Z4ZA 4E1EA 3ICMA 2ZCOA 3VJ9A 1YYSA 4HD1A 5JV1F 3WCDA 2AZKA 3WE9A 5B03A 5H9DA 5ILKA 3B7LA 3WEGA 4GP2A 2RAHA 2Q58A 3ICKA 1RQJA 1WL1A 5AYPA 3BNYA 3LSNA 3M00A 2OA6A 3N1WF 4UMJA 5IMIA 3CC9A 1V4KA 1YV5A 1KIYA 3WCBA 5IK6A 5IMPA 1WMWA 3OACB 2F8ZF 4F62A 4NUAA 1N22A 5B0IA
chains in the Genus database with same CATH topology
2F92F 3DYFA 5ILJA 1KIZA 3TC1A 3WCMA 5DW7A 5IKAA 5DZ2A 3SDVA 5IMNA 5IK0A 4LIXA 5ILZA 3VJEA 4DXJA 5ILIA 1YHLA 5A0JA 3WCAA 3Q1OA 5AHUB 4DEMF 4E9ZA 4KVIA 3TS7A 3WJNA 1DGPA 5DIQF 5HN7A 3PYAA 1HM4A 3RYEA 3M01A 4LPGF 4MC0A 3RYWA 3LK5A 4LZ0A 4H5EF 4LXWA 2QISA 3KROA 3RMGA 1JFAA 2AZLA 3VJ8A 4RXEA 1V4JA 3P8LA 5IVGA 4EA1A 3P5PA 2AZJA 2PS7A 3WSBA 3LVSA 3UCAA 5B0KA 3P41A 2ZCQA 4KWDA 3QKCA 5IN8A 3WEJA 2EWGA 1N1ZA 5IKHA 1HXGA 4NFIF 2J1PA 3ACXA 3G4FA 3N3LF 4GA3A 3OABA 3V1XA 3WCEA 5DGNF 5DJPF 3SDQA 1YYRA 4WK5A 3WCLA 2Q80A 4JYXA 4XQRF 3AQBB 3TFVA 3N49F 1UBYA 1WKZA 2ONHA 5CG6A 1WL3A 2P1CA 1HX9A 1YYTA 4JZXA 3ICNA 4LOBA 2ONGA 5ER8A 3M0GA 4F6VA 4RXAA 5DJRF 5EROA 2Z4WA 4KQ5A 4LZ3A 3KRCA 5JV2F 3WCCA 3WJOA 1FPSA 1V4HA 3ASXA 3WCGA 1YYQA 4QPFA 3M02A 1RQIA 3ICZA 2F9KF 1WY0A 2OPMA 2FORA 3LJIA 4DI5A 2E8UA 3PYBA 5EAUA 2F7MF 3KRFA 3S9VA 2Z52A 3WSAA 3EGTA 3LGKA 4LFEA 3Q2ZA 4LFGA 4QXSF 3KBKA 3N46F 3ADZA 1V4EA 5DJVF 3M9UA 4RNQA 5I1UA 2Z4YA 3IPIA 2Z4XA 4H5DF 3N5HF 4NG6A 3KROB 5B02A 5ERMA 3N1VF 2E92A 3QQVA 4GP1A 3Q30A 4XQTF 3ZOUA 4OGUA 4MC8A 5HNAA 5B00A 3PKOA 2OPNA 2FTZA 3LGZB 5IK9A 5JUZF 3P8RA 4DWGA 3ID0A 4NFKF 2Z78A 1V4IA 5HN8A 3N0GA 4PVYF 5ILYA 1VG3A 2ZY1A 5E8HA 4KVYA 4JZBA 2ZEVA 1EZFA 3OABB 1N24A 5A0KA 1UBVA 2F94F 2E8VA 3VJDA 3PH7A 3APZA 2AELA 3KRPB 4LLTA 2Z7HA 3VJCA 4KK2A 2ZEUA 4LFVF 2Z50A 3NPRA 3NF2A 4KVWA 3N45F 4F6XA 4OMHA 4JXNA 4LZCA 4E9UA 3KRCB 4DWBA 4H5CF 4KPDA 5ILHA 1N23A 4OKMA 3LG5A 3WCFA 4MC3A 4RXCA 3ZCDA 4LUUA 5HN9A 3SDUA 3RBMA 2AETA 3PDEA 4KQUA 3KRFB 1YQ7A 3KRPA 4JVJF 2H8OA 2I19A 4ZQ8A 1DI1A 3VJAA 3NPKA 4KPJA 5A0IA 3LLWA 1RTRA 3BNXA 1HXCA 3AQCB 3ZMCA 1VG4A 5DGSF 3Q2QA 4LA5A 4FP4A 1UBWA 1UBXA 5ERNA 4EA0A 2E8WA 1YHMA 3TFNA 4KVDA 1VG7A 1N21A 4OMGA 3KRAA 5EASA 4N9UA 4DHDA 2Q9YA 1VG6A 3SDRA 3G4DA 3V66A 5DHKA 4OKZA 4KUXA 3WCHA 2F89F 2VF6A 3EFQA 3KB9A 1ZW5A 4KQSA 1YYUA 4P0VA 2E90A 4NKEA 4LLSA 5IL3A 2E8XA 4P0XA 3WJKA 5JA0F 3V1VA 3W7FA 1YHKA 3ACYA 3CP6A 5AELA 1PS1A 2ZCRA 2E8TA 2E4OA 5IL8A 3WCIA 3ACWA 4DZWA 5B0LA 3P5RA 2Z4VA 4KKMA 3S4JA 2PS8A 4KFAA 1WL2A 1HM7A 4XQSF 3WCJA 3AQ0A 4Q23A 5KSXF 3LEEA 4NKFA 2AEKA 4N1ZF 5IM1A 3MAVA 3LMDA 4L2XF 3NRIA 5EATA 3DYHA 5DHIA 2E93A 4LPHF 1JFGA 3N5JF 2O1OA 3LOMA 1N1BA 2OGDA 2E94A 3LZ9A 3WEIA 3WEFA 5JV0F 5AFXA 3ZL6A 3OACA 3CKEA 2Z7IA 4JXYA 3SAEA 1VG2A 4NFJF 1YJ4A 3N3DA 5CG5A 2J1OA 2PS5A 5B01A 5B0MA 3KRAB 5E8KA 2J5CA 4RYPA 4PVXF 1WL0A 4FJQA 3OYRA 4K10A 2PS6A 3N6KF 3SDTA 2Q9ZA 5ILDA 4LA6A 3IBAA 3DYGA 4LTZA 4GAXA 5E8LA 2E91A 4EA2A 4RXDA 1N20A 4LTVA 3WEHA 3ZMBA 3EZ3A 4P0WA 2F8CF 2E95A 3VJBA 3MZVA 2PS4A 3LDWA 3WC9A 3TFPA 5B0JA 3WEKA 3N0FA 5C05A 1HXAA 5DGMF 2DH4A 2ZCSA 3AE0A 2Z4ZA 4E1EA 3ICMA 2ZCOA 3VJ9A 1YYSA 4HD1A 5JV1F 3WCDA 2AZKA 3WE9A 5B03A 5H9DA 5ILKA 3B7LA 3WEGA 4GP2A 2RAHA 2Q58A 3ICKA 1RQJA 1WL1A 5AYPA 3BNYA 3LSNA 3M00A 2OA6A 3N1WF 4UMJA 5IMIA 3CC9A 1V4KA 1YV5A 1KIYA 3WCBA 5IK6A 5IMPA 1WMWA 3OACB 2F8ZF 4F62A 4NUAA 1N22A 5B0IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F92 F;  3DYF A;  5ILJ A;  1KIZ A;  3TC1 A;  3WCM A;  5DW7 A;  5IKA A;  5DZ2 A;  3SDV A;  5IMN A;  5IK0 A;  4LIX A;  5ILZ A;  3VJE A;  4DXJ A;  5ILI A;  1YHL A;  5A0J A;  3WCA A;  3Q1O A;  5AHU B;  4DEM F;  4E9Z A;  4KVI A;  3TS7 A;  3WJN A;  1DGP A;  5DIQ F;  5HN7 A;  3PYA A;  1HM4 A;  3RYE A;  3M01 A;  4LPG F;  4MC0 A;  3RYW A;  3LK5 A;  4LZ0 A;  4H5E F;  4LXW A;  2QIS A;  3KRO A;  3RMG A;  1JFA A;  2AZL A;  3VJ8 A;  4RXE A;  1V4J A;  3P8L A;  5IVG A;  4EA1 A;  3P5P A;  2AZJ A;  2PS7 A;  3WSB A;  3LVS A;  3UCA A;  5B0K A;  3P41 A;  2ZCQ A;  4KWD A;  3QKC A;  5IN8 A;  3WEJ A;  2EWG A;  1N1Z A;  5IKH A;  1HXG A;  4NFI F;  2J1P A;  3ACX A;  3G4F A;  3N3L F;  4GA3 A;  3OAB A;  3V1X A;  3WCE A;  5DGN F;  5DJP F;  3SDQ A;  1YYR A;  4WK5 A;  3WCL A;  2Q80 A;  4JYX A;  4XQR F;  3AQB B;  3TFV A;  3N49 F;  1UBY A;  1WKZ A;  2ONH A;  5CG6 A;  1WL3 A;  2P1C A;  1HX9 A;  1YYT A;  4JZX A;  3ICN A;  4LOB A;  2ONG A;  5ER8 A;  3M0G A;  4F6V A;  4RXA A;  5DJR F;  5ERO A;  2Z4W A;  4KQ5 A;  4LZ3 A;  3KRC A;  5JV2 F;  3WCC A;  3WJO A;  1FPS A;  1V4H A;  3ASX A;  3WCG A;  1YYQ A;  4QPF A;  3M02 A;  1RQI A;  3ICZ A;  2F9K F;  1WY0 A;  2OPM A;  2FOR A;  3LJI A;  4DI5 A;  2E8U A;  3PYB A;  5EAU A;  2F7M F;  3KRF A;  3S9V A;  2Z52 A;  3WSA A;  3EGT A;  3LGK A;  4LFE A;  3Q2Z A;  4LFG A;  4QXS F;  3KBK A;  3N46 F;  3ADZ A;  1V4E A;  5DJV F;  3M9U A;  4RNQ A;  5I1U A;  2Z4Y A;  3IPI A;  2Z4X A;  4H5D F;  3N5H F;  4NG6 A;  3KRO B;  5B02 A;  5ERM A;  3N1V F;  2E92 A;  3QQV A;  4GP1 A;  3Q30 A;  4XQT F;  3ZOU A;  4OGU A;  4MC8 A;  5HNA A;  5B00 A;  3PKO A;  2OPN A;  2FTZ A;  3LGZ B;  5IK9 A;  5JUZ F;  3P8R A;  4DWG A;  3ID0 A;  4NFK F;  2Z78 A;  1V4I A;  5HN8 A;  3N0G A;  4PVY F;  5ILY A;  1VG3 A;  2ZY1 A;  5E8H A;  4KVY A;  4JZB A;  2ZEV A;  1EZF A;  3OAB B;  1N24 A;  5A0K A;  1UBV A;  2F94 F;  2E8V A;  3VJD A;  3PH7 A;  3APZ A;  2AEL A;  3KRP B;  4LLT A;  2Z7H A;  3VJC A;  4KK2 A;  2ZEU A;  4LFV F;  2Z50 A;  3NPR A;  3NF2 A;  4KVW A;  3N45 F;  4F6X A;  4OMH A;  4JXN A;  4LZC A;  4E9U A;  3KRC B;  4DWB A;  4H5C F;  4KPD A;  5ILH A;  1N23 A;  4OKM A;  3LG5 A;  3WCF A;  4MC3 A;  4RXC A;  3ZCD A;  4LUU A;  5HN9 A;  3SDU A;  3RBM A;  2AET A;  3PDE A;  4KQU A;  3KRF B;  1YQ7 A;  3KRP A;  4JVJ F;  2H8O A;  2I19 A;  4ZQ8 A;  1DI1 A;  3VJA A;  3NPK A;  4KPJ A;  5A0I A;  3LLW A;  1RTR A;  3BNX A;  1HXC A;  3AQC B;  3ZMC A;  1VG4 A;  5DGS F;  3Q2Q A;  4LA5 A;  4FP4 A;  1UBW A;  1UBX A;  5ERN A;  4EA0 A;  2E8W A;  1YHM A;  3TFN A;  4KVD A;  1VG7 A;  1N21 A;  4OMG A;  3KRA A;  5EAS A;  4N9U A;  4DHD A;  2Q9Y A;  1VG6 A;  3SDR A;  3G4D A;  3V66 A;  5DHK A;  4OKZ A;  4KUX A;  3WCH A;  2F89 F;  2VF6 A;  3EFQ A;  3KB9 A;  1ZW5 A;  4KQS A;  1YYU A;  4P0V A;  2E90 A;  4NKE A;  4LLS A;  5IL3 A;  2E8X A;  4P0X A;  3WJK A;  5JA0 F;  3V1V A;  3W7F A;  1YHK A;  3ACY A;  3CP6 A;  5AEL A;  1PS1 A;  2ZCR A;  2E8T A;  2E4O A;  5IL8 A;  3WCI A;  3ACW A;  4DZW A;  5B0L A;  3P5R A;  2Z4V A;  4KKM A;  3S4J A;  2PS8 A;  4KFA A;  1WL2 A;  1HM7 A;  4XQS F;  3WCJ A;  3AQ0 A;  4Q23 A;  5KSX F;  3LEE A;  4NKF A;  2AEK A;  4N1Z F;  5IM1 A;  3MAV A;  3LMD A;  4L2X F;  3NRI A;  5EAT A;  3DYH A;  5DHI A;  2E93 A;  4LPH F;  1JFG A;  3N5J F;  2O1O A;  3LOM A;  1N1B A;  2OGD A;  2E94 A;  3LZ9 A;  3WEI A;  3WEF A;  5JV0 F;  5AFX A;  3ZL6 A;  3OAC A;  3CKE A;  2Z7I A;  4JXY A;  3SAE A;  1VG2 A;  4NFJ F;  1YJ4 A;  3N3D A;  5CG5 A;  2J1O A;  2PS5 A;  5B01 A;  5B0M A;  3KRA B;  5E8K A;  2J5C A;  4RYP A;  4PVX F;  1WL0 A;  4FJQ A;  3OYR A;  4K10 A;  2PS6 A;  3N6K F;  3SDT A;  2Q9Z A;  5ILD A;  4LA6 A;  3IBA A;  3DYG A;  4LTZ A;  4GAX A;  5E8L A;  2E91 A;  4EA2 A;  4RXD A;  1N20 A;  4LTV A;  3WEH A;  3ZMB A;  3EZ3 A;  4P0W A;  2F8C F;  2E95 A;  3VJB A;  3MZV A;  2PS4 A;  3LDW A;  3WC9 A;  3TFP A;  5B0J A;  3WEK A;  3N0F A;  5C05 A;  1HXA A;  5DGM F;  2DH4 A;  2ZCS A;  3AE0 A;  2Z4Z A;  4E1E A;  3ICM A;  2ZCO A;  3VJ9 A;  1YYS A;  4HD1 A;  5JV1 F;  3WCD A;  2AZK A;  3WE9 A;  5B03 A;  5H9D A;  5ILK A;  3B7L A;  3WEG A;  4GP2 A;  2RAH A;  2Q58 A;  3ICK A;  1RQJ A;  1WL1 A;  5AYP A;  3BNY A;  3LSN A;  3M00 A;  2OA6 A;  3N1W F;  4UMJ A;  5IMI A;  3CC9 A;  1V4K A;  1YV5 A;  1KIY A;  3WCB A;  5IK6 A;  5IMP A;  1WMW A;  3OAC B;  2F8Z F;  4F62 A;  4NUA A;  1N22 A;  5B0I A; 
#chains in the Genus database with same CATH topology
 2F92 F;  3DYF A;  5ILJ A;  1KIZ A;  3TC1 A;  3WCM A;  5DW7 A;  5IKA A;  5DZ2 A;  3SDV A;  5IMN A;  5IK0 A;  4LIX A;  5ILZ A;  3VJE A;  4DXJ A;  5ILI A;  1YHL A;  5A0J A;  3WCA A;  3Q1O A;  5AHU B;  4DEM F;  4E9Z A;  4KVI A;  3TS7 A;  3WJN A;  1DGP A;  5DIQ F;  5HN7 A;  3PYA A;  1HM4 A;  3RYE A;  3M01 A;  4LPG F;  4MC0 A;  3RYW A;  3LK5 A;  4LZ0 A;  4H5E F;  4LXW A;  2QIS A;  3KRO A;  3RMG A;  1JFA A;  2AZL A;  3VJ8 A;  4RXE A;  1V4J A;  3P8L A;  5IVG A;  4EA1 A;  3P5P A;  2AZJ A;  2PS7 A;  3WSB A;  3LVS A;  3UCA A;  5B0K A;  3P41 A;  2ZCQ A;  4KWD A;  3QKC A;  5IN8 A;  3WEJ A;  2EWG A;  1N1Z A;  5IKH A;  1HXG A;  4NFI F;  2J1P A;  3ACX A;  3G4F A;  3N3L F;  4GA3 A;  3OAB A;  3V1X A;  3WCE A;  5DGN F;  5DJP F;  3SDQ A;  1YYR A;  4WK5 A;  3WCL A;  2Q80 A;  4JYX A;  4XQR F;  3AQB B;  3TFV A;  3N49 F;  1UBY A;  1WKZ A;  2ONH A;  5CG6 A;  1WL3 A;  2P1C A;  1HX9 A;  1YYT A;  4JZX A;  3ICN A;  4LOB A;  2ONG A;  5ER8 A;  3M0G A;  4F6V A;  4RXA A;  5DJR F;  5ERO A;  2Z4W A;  4KQ5 A;  4LZ3 A;  3KRC A;  5JV2 F;  3WCC A;  3WJO A;  1FPS A;  1V4H A;  3ASX A;  3WCG A;  1YYQ A;  4QPF A;  3M02 A;  1RQI A;  3ICZ A;  2F9K F;  1WY0 A;  2OPM A;  2FOR A;  3LJI A;  4DI5 A;  2E8U A;  3PYB A;  5EAU A;  2F7M F;  3KRF A;  3S9V A;  2Z52 A;  3WSA A;  3EGT A;  3LGK A;  4LFE A;  3Q2Z A;  4LFG A;  4QXS F;  3KBK A;  3N46 F;  3ADZ A;  1V4E A;  5DJV F;  3M9U A;  4RNQ A;  5I1U A;  2Z4Y A;  3IPI A;  2Z4X A;  4H5D F;  3N5H F;  4NG6 A;  3KRO B;  5B02 A;  5ERM A;  3N1V F;  2E92 A;  3QQV A;  4GP1 A;  3Q30 A;  4XQT F;  3ZOU A;  4OGU A;  4MC8 A;  5HNA A;  5B00 A;  3PKO A;  2OPN A;  2FTZ A;  3LGZ B;  5IK9 A;  5JUZ F;  3P8R A;  4DWG A;  3ID0 A;  4NFK F;  2Z78 A;  1V4I A;  5HN8 A;  3N0G A;  4PVY F;  5ILY A;  1VG3 A;  2ZY1 A;  5E8H A;  4KVY A;  4JZB A;  2ZEV A;  1EZF A;  3OAB B;  1N24 A;  5A0K A;  1UBV A;  2F94 F;  2E8V A;  3VJD A;  3PH7 A;  3APZ A;  2AEL A;  3KRP B;  4LLT A;  2Z7H A;  3VJC A;  4KK2 A;  2ZEU A;  4LFV F;  2Z50 A;  3NPR A;  3NF2 A;  4KVW A;  3N45 F;  4F6X A;  4OMH A;  4JXN A;  4LZC A;  4E9U A;  3KRC B;  4DWB A;  4H5C F;  4KPD A;  5ILH A;  1N23 A;  4OKM A;  3LG5 A;  3WCF A;  4MC3 A;  4RXC A;  3ZCD A;  4LUU A;  5HN9 A;  3SDU A;  3RBM A;  2AET A;  3PDE A;  4KQU A;  3KRF B;  1YQ7 A;  3KRP A;  4JVJ F;  2H8O A;  2I19 A;  4ZQ8 A;  1DI1 A;  3VJA A;  3NPK A;  4KPJ A;  5A0I A;  3LLW A;  1RTR A;  3BNX A;  1HXC A;  3AQC B;  3ZMC A;  1VG4 A;  5DGS F;  3Q2Q A;  4LA5 A;  4FP4 A;  1UBW A;  1UBX A;  5ERN A;  4EA0 A;  2E8W A;  1YHM A;  3TFN A;  4KVD A;  1VG7 A;  1N21 A;  4OMG A;  3KRA A;  5EAS A;  4N9U A;  4DHD A;  2Q9Y A;  1VG6 A;  3SDR A;  3G4D A;  3V66 A;  5DHK A;  4OKZ A;  4KUX A;  3WCH A;  2F89 F;  2VF6 A;  3EFQ A;  3KB9 A;  1ZW5 A;  4KQS A;  1YYU A;  4P0V A;  2E90 A;  4NKE A;  4LLS A;  5IL3 A;  2E8X A;  4P0X A;  3WJK A;  5JA0 F;  3V1V A;  3W7F A;  1YHK A;  3ACY A;  3CP6 A;  5AEL A;  1PS1 A;  2ZCR A;  2E8T A;  2E4O A;  5IL8 A;  3WCI A;  3ACW A;  4DZW A;  5B0L A;  3P5R A;  2Z4V A;  4KKM A;  3S4J A;  2PS8 A;  4KFA A;  1WL2 A;  1HM7 A;  4XQS F;  3WCJ A;  3AQ0 A;  4Q23 A;  5KSX F;  3LEE A;  4NKF A;  2AEK A;  4N1Z F;  5IM1 A;  3MAV A;  3LMD A;  4L2X F;  3NRI A;  5EAT A;  3DYH A;  5DHI A;  2E93 A;  4LPH F;  1JFG A;  3N5J F;  2O1O A;  3LOM A;  1N1B A;  2OGD A;  2E94 A;  3LZ9 A;  3WEI A;  3WEF A;  5JV0 F;  5AFX A;  3ZL6 A;  3OAC A;  3CKE A;  2Z7I A;  4JXY A;  3SAE A;  1VG2 A;  4NFJ F;  1YJ4 A;  3N3D A;  5CG5 A;  2J1O A;  2PS5 A;  5B01 A;  5B0M A;  3KRA B;  5E8K A;  2J5C A;  4RYP A;  4PVX F;  1WL0 A;  4FJQ A;  3OYR A;  4K10 A;  2PS6 A;  3N6K F;  3SDT A;  2Q9Z A;  5ILD A;  4LA6 A;  3IBA A;  3DYG A;  4LTZ A;  4GAX A;  5E8L A;  2E91 A;  4EA2 A;  4RXD A;  1N20 A;  4LTV A;  3WEH A;  3ZMB A;  3EZ3 A;  4P0W A;  2F8C F;  2E95 A;  3VJB A;  3MZV A;  2PS4 A;  3LDW A;  3WC9 A;  3TFP A;  5B0J A;  3WEK A;  3N0F A;  5C05 A;  1HXA A;  5DGM F;  2DH4 A;  2ZCS A;  3AE0 A;  2Z4Z A;  4E1E A;  3ICM A;  2ZCO A;  3VJ9 A;  1YYS A;  4HD1 A;  5JV1 F;  3WCD A;  2AZK A;  3WE9 A;  5B03 A;  5H9D A;  5ILK A;  3B7L A;  3WEG A;  4GP2 A;  2RAH A;  2Q58 A;  3ICK A;  1RQJ A;  1WL1 A;  5AYP A;  3BNY A;  3LSN A;  3M00 A;  2OA6 A;  3N1W F;  4UMJ A;  5IMI A;  3CC9 A;  1V4K A;  1YV5 A;  1KIY A;  3WCB A;  5IK6 A;  5IMP A;  1WMW A;  3OAC B;  2F8Z F;  4F62 A;  4NUA A;  1N22 A;  5B0I A; 
#chains in the Genus database with same CATH homology
 2F92 F;  3DYF A;  5ILJ A;  1KIZ A;  3TC1 A;  3WCM A;  5DW7 A;  5IKA A;  5DZ2 A;  3SDV A;  5IMN A;  5IK0 A;  4LIX A;  5ILZ A;  3VJE A;  4DXJ A;  5ILI A;  1YHL A;  5A0J A;  3WCA A;  3Q1O A;  5AHU B;  4DEM F;  4E9Z A;  4KVI A;  3TS7 A;  3WJN A;  1DGP A;  5DIQ F;  5HN7 A;  3PYA A;  1HM4 A;  3RYE A;  3M01 A;  4LPG F;  4MC0 A;  3RYW A;  3LK5 A;  4LZ0 A;  4H5E F;  4LXW A;  2QIS A;  3KRO A;  3RMG A;  1JFA A;  2AZL A;  3VJ8 A;  4RXE A;  1V4J A;  3P8L A;  5IVG A;  4EA1 A;  3P5P A;  2AZJ A;  2PS7 A;  3WSB A;  3LVS A;  3UCA A;  5B0K A;  3P41 A;  2ZCQ A;  4KWD A;  3QKC A;  5IN8 A;  3WEJ A;  2EWG A;  1N1Z A;  5IKH A;  1HXG A;  4NFI F;  2J1P A;  3ACX A;  3G4F A;  3N3L F;  4GA3 A;  3OAB A;  3V1X A;  3WCE A;  5DGN F;  5DJP F;  3SDQ A;  1YYR A;  4WK5 A;  3WCL A;  2Q80 A;  4JYX A;  4XQR F;  3AQB B;  3TFV A;  3N49 F;  1UBY A;  1WKZ A;  2ONH A;  5CG6 A;  1WL3 A;  2P1C A;  1HX9 A;  1YYT A;  4JZX A;  3ICN A;  4LOB A;  2ONG A;  5ER8 A;  3M0G A;  4F6V A;  4RXA A;  5DJR F;  5ERO A;  2Z4W A;  4KQ5 A;  4LZ3 A;  3KRC A;  5JV2 F;  3WCC A;  3WJO A;  1FPS A;  1V4H A;  3ASX A;  3WCG A;  1YYQ A;  4QPF A;  3M02 A;  1RQI A;  3ICZ A;  2F9K F;  1WY0 A;  2OPM A;  2FOR A;  3LJI A;  4DI5 A;  2E8U A;  3PYB A;  5EAU A;  2F7M F;  3KRF A;  3S9V A;  2Z52 A;  3WSA A;  3EGT A;  3LGK A;  4LFE A;  3Q2Z A;  4LFG A;  4QXS F;  3KBK A;  3N46 F;  3ADZ A;  1V4E A;  5DJV F;  3M9U A;  4RNQ A;  5I1U A;  2Z4Y A;  3IPI A;  2Z4X A;  4H5D F;  3N5H F;  4NG6 A;  3KRO B;  5B02 A;  5ERM A;  3N1V F;  2E92 A;  3QQV A;  4GP1 A;  3Q30 A;  4XQT F;  3ZOU A;  4OGU A;  4MC8 A;  5HNA A;  5B00 A;  3PKO A;  2OPN A;  2FTZ A;  3LGZ B;  5IK9 A;  5JUZ F;  3P8R A;  4DWG A;  3ID0 A;  4NFK F;  2Z78 A;  1V4I A;  5HN8 A;  3N0G A;  4PVY F;  5ILY A;  1VG3 A;  2ZY1 A;  5E8H A;  4KVY A;  4JZB A;  2ZEV A;  1EZF A;  3OAB B;  1N24 A;  5A0K A;  1UBV A;  2F94 F;  2E8V A;  3VJD A;  3PH7 A;  3APZ A;  2AEL A;  3KRP B;  4LLT A;  2Z7H A;  3VJC A;  4KK2 A;  2ZEU A;  4LFV F;  2Z50 A;  3NPR A;  3NF2 A;  4KVW A;  3N45 F;  4F6X A;  4OMH A;  4JXN A;  4LZC A;  4E9U A;  3KRC B;  4DWB A;  4H5C F;  4KPD A;  5ILH A;  1N23 A;  4OKM A;  3LG5 A;  3WCF A;  4MC3 A;  4RXC A;  3ZCD A;  4LUU A;  5HN9 A;  3SDU A;  3RBM A;  2AET A;  3PDE A;  4KQU A;  3KRF B;  1YQ7 A;  3KRP A;  4JVJ F;  2H8O A;  2I19 A;  4ZQ8 A;  1DI1 A;  3VJA A;  3NPK A;  4KPJ A;  5A0I A;  3LLW A;  1RTR A;  3BNX A;  1HXC A;  3AQC B;  3ZMC A;  1VG4 A;  5DGS F;  3Q2Q A;  4LA5 A;  4FP4 A;  1UBW A;  1UBX A;  5ERN A;  4EA0 A;  2E8W A;  1YHM A;  3TFN A;  4KVD A;  1VG7 A;  1N21 A;  4OMG A;  3KRA A;  5EAS A;  4N9U A;  4DHD A;  2Q9Y A;  1VG6 A;  3SDR A;  3G4D A;  3V66 A;  5DHK A;  4OKZ A;  4KUX A;  3WCH A;  2F89 F;  2VF6 A;  3EFQ A;  3KB9 A;  1ZW5 A;  4KQS A;  1YYU A;  4P0V A;  2E90 A;  4NKE A;  4LLS A;  5IL3 A;  2E8X A;  4P0X A;  3WJK A;  5JA0 F;  3V1V A;  3W7F A;  1YHK A;  3ACY A;  3CP6 A;  5AEL A;  1PS1 A;  2ZCR A;  2E8T A;  2E4O A;  5IL8 A;  3WCI A;  3ACW A;  4DZW A;  5B0L A;  3P5R A;  2Z4V A;  4KKM A;  3S4J A;  2PS8 A;  4KFA A;  1WL2 A;  1HM7 A;  4XQS F;  3WCJ A;  3AQ0 A;  4Q23 A;  5KSX F;  3LEE A;  4NKF A;  2AEK A;  4N1Z F;  5IM1 A;  3MAV A;  3LMD A;  4L2X F;  3NRI A;  5EAT A;  3DYH A;  5DHI A;  2E93 A;  4LPH F;  1JFG A;  3N5J F;  2O1O A;  3LOM A;  1N1B A;  2OGD A;  2E94 A;  3LZ9 A;  3WEI A;  3WEF A;  5JV0 F;  5AFX A;  3ZL6 A;  3OAC A;  3CKE A;  2Z7I A;  4JXY A;  3SAE A;  1VG2 A;  4NFJ F;  1YJ4 A;  3N3D A;  5CG5 A;  2J1O A;  2PS5 A;  5B01 A;  5B0M A;  3KRA B;  5E8K A;  2J5C A;  4RYP A;  4PVX F;  1WL0 A;  4FJQ A;  3OYR A;  4K10 A;  2PS6 A;  3N6K F;  3SDT A;  2Q9Z A;  5ILD A;  4LA6 A;  3IBA A;  3DYG A;  4LTZ A;  4GAX A;  5E8L A;  2E91 A;  4EA2 A;  4RXD A;  1N20 A;  4LTV A;  3WEH A;  3ZMB A;  3EZ3 A;  4P0W A;  2F8C F;  2E95 A;  3VJB A;  3MZV A;  2PS4 A;  3LDW A;  3WC9 A;  3TFP A;  5B0J A;  3WEK A;  3N0F A;  5C05 A;  1HXA A;  5DGM F;  2DH4 A;  2ZCS A;  3AE0 A;  2Z4Z A;  4E1E A;  3ICM A;  2ZCO A;  3VJ9 A;  1YYS A;  4HD1 A;  5JV1 F;  3WCD A;  2AZK A;  3WE9 A;  5B03 A;  5H9D A;  5ILK A;  3B7L A;  3WEG A;  4GP2 A;  2RAH A;  2Q58 A;  3ICK A;  1RQJ A;  1WL1 A;  5AYP A;  3BNY A;  3LSN A;  3M00 A;  2OA6 A;  3N1W F;  4UMJ A;  5IMI A;  3CC9 A;  1V4K A;  1YV5 A;  1KIY A;  3WCB A;  5IK6 A;  5IMP A;  1WMW A;  3OAC B;  2F8Z F;  4F62 A;  4NUA A;  1N22 A;  5B0I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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