3WPSA

Crystal structure of the gap domain of mgcracgap(s387d)
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
201
structure length
201
Chain Sequence
IGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRIDGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQPKVVERLLSLPLEYWSQFMMVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein
molecule keywords Rac GTPase-activating protein 1
publication title crystal structure of the GAP domain of MgcRacGAP
rcsb
source organism Homo sapiens
total genus 60
structure length 201
sequence length 201
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3wpsA00
2OSAA 2OVJA 1GRNB 3WPQA 3WPSA 2EE4A 2MBGA 5JD0A 3KUQA 1F7CA 3IUGA 5HPYA 3W6RA 3MSXB 1OW3A 5JCPA 3QISA 1AM4A 3BYIA 2NGRB 1XA6A 5IRCA 3FK2A 1PBWA 5C2JA 2XS6A 1TX4A 5C5SA 3EAPA 3CXLA 1RGPA 2QV2A 2EE5A
chains in the Genus database with same CATH superfamily
2OSAA 2OVJA 1GRNB 3WPQA 3WPSA 2EE4A 2MBGA 5JD0A 3KUQA 1F7CA 3IUGA 5HPYA 3W6RA 3MSXB 1OW3A 5JCPA 3QISA 1AM4A 3BYIA 2NGRB 1XA6A 5IRCA 3FK2A 1PBWA 5C2JA 2XS6A 1TX4A 5C5SA 3EAPA 3CXLA 1RGPA 2QV2A 2EE5A
chains in the Genus database with same CATH topology
2OSAA 2OVJA 1GRNB 3WPQA 3WPSA 2EE4A 2MBGA 5JD0A 3KUQA 1F7CA 3IUGA 5HPYA 3W6RA 3MSXB 1OW3A 5JCPA 3QISA 1AM4A 3BYIA 2NGRB 1XA6A 5IRCA 3FK2A 1PBWA 5C2JA 2XS6A 1TX4A 5C5SA 3EAPA 3CXLA 1RGPA 2QV2A 2EE5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OSA A;  2OVJ A;  1GRN B;  3WPQ A;  3WPS A;  2EE4 A;  2MBG A;  5JD0 A;  3KUQ A;  1F7C A;  3IUG A;  5HPY A;  3W6R A;  3MSX B;  1OW3 A;  5JCP A;  3QIS A;  1AM4 A;  3BYI A;  2NGR B;  1XA6 A;  5IRC A;  3FK2 A;  1PBW A;  5C2J A;  2XS6 A;  1TX4 A;  5C5S A;  3EAP A;  3CXL A;  1RGP A;  2QV2 A;  2EE5 A; 
#chains in the Genus database with same CATH topology
 2OSA A;  2OVJ A;  1GRN B;  3WPQ A;  3WPS A;  2EE4 A;  2MBG A;  5JD0 A;  3KUQ A;  1F7C A;  3IUG A;  5HPY A;  3W6R A;  3MSX B;  1OW3 A;  5JCP A;  3QIS A;  1AM4 A;  3BYI A;  2NGR B;  1XA6 A;  5IRC A;  3FK2 A;  1PBW A;  5C2J A;  2XS6 A;  1TX4 A;  5C5S A;  3EAP A;  3CXL A;  1RGP A;  2QV2 A;  2EE5 A; 
#chains in the Genus database with same CATH homology
 2OSA A;  2OVJ A;  1GRN B;  3WPQ A;  3WPS A;  2EE4 A;  2MBG A;  5JD0 A;  3KUQ A;  1F7C A;  3IUG A;  5HPY A;  3W6R A;  3MSX B;  1OW3 A;  5JCP A;  3QIS A;  1AM4 A;  3BYI A;  2NGR B;  1XA6 A;  5IRC A;  3FK2 A;  1PBW A;  5C2J A;  2XS6 A;  1TX4 A;  5C5S A;  3EAP A;  3CXL A;  1RGP A;  2QV2 A;  2EE5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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