3WTMA

Crystal structure of lymnaea stagnalis acetylcholine-binding protein q55r mutant complexed with nitromethylene analogue of imidacloprid
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
207
structure length
207
Chain Sequence
ADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQRTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions
pubmed doi rcsb
molecule keywords Acetylcholine-binding protein
molecule tags Signaling protein
source organism Lymnaea stagnalis
total genus 48
structure length 207
sequence length 207
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2014-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 3wtmA00
4TWHA 2QC1B 3EHZA 4UXUA 4ZK1A 4TNVA 3TLWA 5HCJA 3SQ9A 3RQUA 2XQ6A 2Y58A 4UM3P 5HEOA 3UU6A 2PH9A 4BQTA 2BYSA 2BG9A 5FJVA 1UV6A 4EZ1A 5AINA 4D01A 3GUAA 2C9TA 2Y56A 3T4MA 2XQ7A 3WTJA 4UY2A 4XK9A 2BYQA 5AFJA 3UU5A 4ZK4A 3UQ7A 3WIPA 3PEOA 4UM3A 3ZDGA 5HEUA 2Y57A 2XQ8A 3PMZA 3UUBA 3SIOA 2XYTA 2BR8A 4TWFA 3P4WA 3C79A 3TLTA 3WTLA 5LXBA 4HFBA 2X00D 3UU3A 3WTIA 2XNTA 5TVCA 5BRXA 5J5HA 3ZDHA 4LMLA 4BFQA 5IUXA 2X00A 3RQWA 3U8NA 2PGZA 5L4HA 3U8JA 2YN6A 1I9BA 2BYNA 3RIFA 2WNLA 3TLSA 3WTOA 3WTNA 4A98A 4IL9A 4Z91A 2BG9C 4QACA 4ALXA 2XYSA 2WNCA 3JADA 4PIRA 5CFBA 5LG3A 3EAMA 2BR7A 2Y7YA 5SYOA 4FRRA 5KE4A 2XZ6A 2YKSA 3EI0A 2UZ6A 4HFDA 3UU4A 2XQ3A 4ZRUA 3U8KA 2XZ5A 3TLVA 4ILBA 4DBMA 4ZZCA 4HFHA 4A97A 2YMDA 4AFTA 3RHWA 3UU8A 5BP0A 2VL0A 5AFLA 4WV9A 4HFEA 4HFCA 2XQ9A 5AFNA 5J5GA 3JAFA 4COFA 3WTHA 2W8FA 5AFMB 1UX2A 5J0ZA 3RIAA 5HCMA 2XQ4A 5J5FA 4QH5A 1UW6A 4IL4A 2WN9A 3U8LA 3WTKA 3U8MA 5BW2A 4AFHA 4ZJTA 2BYPA 2WNJA 2BG9E 3SQ6A 4LMJA 2YOEA 2BG9B 4LMKA 4ZR6A 4XHEA 4ZZBA 5JMEA 2XQ5A 2XNVA 3UQ4A 2WZYA 5L47A 2XNUA 2W8GA 4TNWA 4UM3S 5AFMA 3IGQA 5HEHA 5J5IA 5CO5A 3ZKRA 5HEGA 4F8HA 4IREA 4QAAA 4QH4A 4AFGA 3P50A 2XQAA 5AFKA 2Y54A 3C84A 5KZUA 4B5DA 5AFHA 4NZBA 3SH1A 4HFIA 2ZJUA 2ZJVA 3TLUA 4NPPA 5L4EA 2YMEA 2BYRA 4ILCA 4ZJSA 3JAEA 3LSVA 2BJ0A 4X5TA 4TWDA 5HEJA 3WTMA 4UM1A 4ILAA 3RI5A 4QH1A 4Z90A 4QABA 4HQPA
chains in the Genus database with same CATH superfamily
4TWHA 2QC1B 3EHZA 4UXUA 4ZK1A 4TNVA 3TLWA 5HCJA 3SQ9A 3RQUA 2XQ6A 2Y58A 4UM3P 5HEOA 3UU6A 2PH9A 4BQTA 2BYSA 2BG9A 5FJVA 1UV6A 4EZ1A 5AINA 4D01A 3GUAA 2C9TA 2Y56A 3T4MA 2XQ7A 3WTJA 4UY2A 4XK9A 2BYQA 5AFJA 3UU5A 4ZK4A 3UQ7A 3WIPA 3PEOA 4UM3A 3ZDGA 5HEUA 2Y57A 2XQ8A 3PMZA 3UUBA 3SIOA 2XYTA 2BR8A 4TWFA 3P4WA 3C79A 3TLTA 3WTLA 5LXBA 4HFBA 2X00D 3UU3A 3WTIA 2XNTA 5TVCA 5BRXA 5J5HA 3ZDHA 4LMLA 4BFQA 5IUXA 2X00A 3RQWA 3U8NA 2PGZA 5L4HA 3U8JA 2YN6A 1I9BA 2BYNA 3RIFA 2WNLA 3TLSA 3WTOA 3WTNA 4A98A 4IL9A 4Z91A 2BG9C 4QACA 4ALXA 2XYSA 2WNCA 3JADA 4PIRA 5CFBA 5LG3A 3EAMA 2BR7A 2Y7YA 5SYOA 4FRRA 5KE4A 2XZ6A 2YKSA 3EI0A 2UZ6A 4HFDA 3UU4A 2XQ3A 4ZRUA 3U8KA 2XZ5A 3TLVA 4ILBA 4DBMA 4ZZCA 4HFHA 4A97A 2YMDA 4AFTA 3RHWA 3UU8A 5BP0A 2VL0A 5AFLA 4WV9A 4HFEA 4HFCA 2XQ9A 5AFNA 5J5GA 3JAFA 4COFA 3WTHA 2W8FA 5AFMB 1UX2A 5J0ZA 3RIAA 5HCMA 2XQ4A 5J5FA 4QH5A 1UW6A 4IL4A 2WN9A 3U8LA 3WTKA 3U8MA 5BW2A 4AFHA 4ZJTA 2BYPA 2WNJA 2BG9E 3SQ6A 4LMJA 2YOEA 2BG9B 4LMKA 4ZR6A 4XHEA 4ZZBA 5JMEA 2XQ5A 2XNVA 3UQ4A 2WZYA 5L47A 2XNUA 2W8GA 4TNWA 4UM3S 5AFMA 3IGQA 5HEHA 5J5IA 5CO5A 3ZKRA 5HEGA 4F8HA 4IREA 4QAAA 4QH4A 4AFGA 3P50A 2XQAA 5AFKA 2Y54A 3C84A 5KZUA 4B5DA 5AFHA 4NZBA 3SH1A 4HFIA 2ZJUA 2ZJVA 3TLUA 4NPPA 5L4EA 2YMEA 2BYRA 4ILCA 4ZJSA 3JAEA 3LSVA 2BJ0A 4X5TA 4TWDA 5HEJA 3WTMA 4UM1A 4ILAA 3RI5A 4QH1A 4Z90A 4QABA 4HQPA
chains in the Genus database with same CATH topology
4TWHA 2QC1B 3EHZA 4UXUA 4ZK1A 4TNVA 3TLWA 5HCJA 3SQ9A 3RQUA 2XQ6A 2Y58A 4UM3P 5HEOA 3UU6A 2PH9A 4BQTA 2BYSA 2BG9A 5FJVA 1UV6A 4EZ1A 5AINA 4D01A 3GUAA 2C9TA 2Y56A 3T4MA 2XQ7A 3WTJA 4UY2A 4XK9A 2BYQA 5AFJA 3UU5A 4ZK4A 3UQ7A 3WIPA 3PEOA 4UM3A 3ZDGA 5HEUA 2Y57A 2XQ8A 3PMZA 3UUBA 3SIOA 2XYTA 2BR8A 4TWFA 3P4WA 3C79A 3TLTA 3WTLA 5LXBA 4HFBA 2X00D 3UU3A 3WTIA 2XNTA 5TVCA 5BRXA 5J5HA 3ZDHA 4LMLA 4BFQA 5IUXA 2X00A 3RQWA 3U8NA 2PGZA 5L4HA 3U8JA 2YN6A 1I9BA 2BYNA 3RIFA 2WNLA 3TLSA 3WTOA 3WTNA 4A98A 4IL9A 4Z91A 2BG9C 4QACA 4ALXA 2XYSA 2WNCA 3JADA 4PIRA 5CFBA 5LG3A 3EAMA 2BR7A 2Y7YA 5SYOA 4FRRA 5KE4A 2XZ6A 2YKSA 3EI0A 2UZ6A 4HFDA 3UU4A 2XQ3A 4ZRUA 3U8KA 2XZ5A 3TLVA 4ILBA 4DBMA 4ZZCA 4HFHA 4A97A 2YMDA 4AFTA 3RHWA 3UU8A 5BP0A 2VL0A 5AFLA 4WV9A 4HFEA 4HFCA 2XQ9A 5AFNA 5J5GA 3JAFA 4COFA 3WTHA 2W8FA 5AFMB 1UX2A 5J0ZA 3RIAA 5HCMA 2XQ4A 5J5FA 4QH5A 1UW6A 4IL4A 2WN9A 3U8LA 3WTKA 3U8MA 5BW2A 4AFHA 4ZJTA 2BYPA 2WNJA 2BG9E 3SQ6A 4LMJA 2YOEA 2BG9B 4LMKA 4ZR6A 4XHEA 4ZZBA 5JMEA 2XQ5A 2XNVA 3UQ4A 2WZYA 5L47A 2XNUA 2W8GA 4TNWA 4UM3S 5AFMA 3IGQA 5HEHA 5J5IA 5CO5A 3ZKRA 5HEGA 4F8HA 4IREA 4QAAA 4QH4A 4AFGA 3P50A 2XQAA 5AFKA 2Y54A 3C84A 5KZUA 4B5DA 5AFHA 4NZBA 3SH1A 4HFIA 2ZJUA 2ZJVA 3TLUA 4NPPA 5L4EA 2YMEA 2BYRA 4ILCA 4ZJSA 3JAEA 3LSVA 2BJ0A 4X5TA 4TWDA 5HEJA 3WTMA 4UM1A 4ILAA 3RI5A 4QH1A 4Z90A 4QABA 4HQPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TWH A;  2QC1 B;  3EHZ A;  4UXU A;  4ZK1 A;  4TNV A;  3TLW A;  5HCJ A;  3SQ9 A;  3RQU A;  2XQ6 A;  2Y58 A;  4UM3 P;  5HEO A;  3UU6 A;  2PH9 A;  4BQT A;  2BYS A;  2BG9 A;  5FJV A;  1UV6 A;  4EZ1 A;  5AIN A;  4D01 A;  3GUA A;  2C9T A;  2Y56 A;  3T4M A;  2XQ7 A;  3WTJ A;  4UY2 A;  4XK9 A;  2BYQ A;  5AFJ A;  3UU5 A;  4ZK4 A;  3UQ7 A;  3WIP A;  3PEO A;  4UM3 A;  3ZDG A;  5HEU A;  2Y57 A;  2XQ8 A;  3PMZ A;  3UUB A;  3SIO A;  2XYT A;  2BR8 A;  4TWF A;  3P4W A;  3C79 A;  3TLT A;  3WTL A;  5LXB A;  4HFB A;  2X00 D;  3UU3 A;  3WTI A;  2XNT A;  5TVC A;  5BRX A;  5J5H A;  3ZDH A;  4LML A;  4BFQ A;  5IUX A;  2X00 A;  3RQW A;  3U8N A;  2PGZ A;  5L4H A;  3U8J A;  2YN6 A;  1I9B A;  2BYN A;  3RIF A;  2WNL A;  3TLS A;  3WTO A;  3WTN A;  4A98 A;  4IL9 A;  4Z91 A;  2BG9 C;  4QAC A;  4ALX A;  2XYS A;  2WNC A;  3JAD A;  4PIR A;  5CFB A;  5LG3 A;  3EAM A;  2BR7 A;  2Y7Y A;  5SYO A;  4FRR A;  5KE4 A;  2XZ6 A;  2YKS A;  3EI0 A;  2UZ6 A;  4HFD A;  3UU4 A;  2XQ3 A;  4ZRU A;  3U8K A;  2XZ5 A;  3TLV A;  4ILB A;  4DBM A;  4ZZC A;  4HFH A;  4A97 A;  2YMD A;  4AFT A;  3RHW A;  3UU8 A;  5BP0 A;  2VL0 A;  5AFL A;  4WV9 A;  4HFE A;  4HFC A;  2XQ9 A;  5AFN A;  5J5G A;  3JAF A;  4COF A;  3WTH A;  2W8F A;  5AFM B;  1UX2 A;  5J0Z A;  3RIA A;  5HCM A;  2XQ4 A;  5J5F A;  4QH5 A;  1UW6 A;  4IL4 A;  2WN9 A;  3U8L A;  3WTK A;  3U8M A;  5BW2 A;  4AFH A;  4ZJT A;  2BYP A;  2WNJ A;  2BG9 E;  3SQ6 A;  4LMJ A;  2YOE A;  2BG9 B;  4LMK A;  4ZR6 A;  4XHE A;  4ZZB A;  5JME A;  2XQ5 A;  2XNV A;  3UQ4 A;  2WZY A;  5L47 A;  2XNU A;  2W8G A;  4TNW A;  4UM3 S;  5AFM A;  3IGQ A;  5HEH A;  5J5I A;  5CO5 A;  3ZKR A;  5HEG A;  4F8H A;  4IRE A;  4QAA A;  4QH4 A;  4AFG A;  3P50 A;  2XQA A;  5AFK A;  2Y54 A;  3C84 A;  5KZU A;  4B5D A;  5AFH A;  4NZB A;  3SH1 A;  4HFI A;  2ZJU A;  2ZJV A;  3TLU A;  4NPP A;  5L4E A;  2YME A;  2BYR A;  4ILC A;  4ZJS A;  3JAE A;  3LSV A;  2BJ0 A;  4X5T A;  4TWD A;  5HEJ A;  3WTM A;  4UM1 A;  4ILA A;  3RI5 A;  4QH1 A;  4Z90 A;  4QAB A;  4HQP A; 
#chains in the Genus database with same CATH topology
 4TWH A;  2QC1 B;  3EHZ A;  4UXU A;  4ZK1 A;  4TNV A;  3TLW A;  5HCJ A;  3SQ9 A;  3RQU A;  2XQ6 A;  2Y58 A;  4UM3 P;  5HEO A;  3UU6 A;  2PH9 A;  4BQT A;  2BYS A;  2BG9 A;  5FJV A;  1UV6 A;  4EZ1 A;  5AIN A;  4D01 A;  3GUA A;  2C9T A;  2Y56 A;  3T4M A;  2XQ7 A;  3WTJ A;  4UY2 A;  4XK9 A;  2BYQ A;  5AFJ A;  3UU5 A;  4ZK4 A;  3UQ7 A;  3WIP A;  3PEO A;  4UM3 A;  3ZDG A;  5HEU A;  2Y57 A;  2XQ8 A;  3PMZ A;  3UUB A;  3SIO A;  2XYT A;  2BR8 A;  4TWF A;  3P4W A;  3C79 A;  3TLT A;  3WTL A;  5LXB A;  4HFB A;  2X00 D;  3UU3 A;  3WTI A;  2XNT A;  5TVC A;  5BRX A;  5J5H A;  3ZDH A;  4LML A;  4BFQ A;  5IUX A;  2X00 A;  3RQW A;  3U8N A;  2PGZ A;  5L4H A;  3U8J A;  2YN6 A;  1I9B A;  2BYN A;  3RIF A;  2WNL A;  3TLS A;  3WTO A;  3WTN A;  4A98 A;  4IL9 A;  4Z91 A;  2BG9 C;  4QAC A;  4ALX A;  2XYS A;  2WNC A;  3JAD A;  4PIR A;  5CFB A;  5LG3 A;  3EAM A;  2BR7 A;  2Y7Y A;  5SYO A;  4FRR A;  5KE4 A;  2XZ6 A;  2YKS A;  3EI0 A;  2UZ6 A;  4HFD A;  3UU4 A;  2XQ3 A;  4ZRU A;  3U8K A;  2XZ5 A;  3TLV A;  4ILB A;  4DBM A;  4ZZC A;  4HFH A;  4A97 A;  2YMD A;  4AFT A;  3RHW A;  3UU8 A;  5BP0 A;  2VL0 A;  5AFL A;  4WV9 A;  4HFE A;  4HFC A;  2XQ9 A;  5AFN A;  5J5G A;  3JAF A;  4COF A;  3WTH A;  2W8F A;  5AFM B;  1UX2 A;  5J0Z A;  3RIA A;  5HCM A;  2XQ4 A;  5J5F A;  4QH5 A;  1UW6 A;  4IL4 A;  2WN9 A;  3U8L A;  3WTK A;  3U8M A;  5BW2 A;  4AFH A;  4ZJT A;  2BYP A;  2WNJ A;  2BG9 E;  3SQ6 A;  4LMJ A;  2YOE A;  2BG9 B;  4LMK A;  4ZR6 A;  4XHE A;  4ZZB A;  5JME A;  2XQ5 A;  2XNV A;  3UQ4 A;  2WZY A;  5L47 A;  2XNU A;  2W8G A;  4TNW A;  4UM3 S;  5AFM A;  3IGQ A;  5HEH A;  5J5I A;  5CO5 A;  3ZKR A;  5HEG A;  4F8H A;  4IRE A;  4QAA A;  4QH4 A;  4AFG A;  3P50 A;  2XQA A;  5AFK A;  2Y54 A;  3C84 A;  5KZU A;  4B5D A;  5AFH A;  4NZB A;  3SH1 A;  4HFI A;  2ZJU A;  2ZJV A;  3TLU A;  4NPP A;  5L4E A;  2YME A;  2BYR A;  4ILC A;  4ZJS A;  3JAE A;  3LSV A;  2BJ0 A;  4X5T A;  4TWD A;  5HEJ A;  3WTM A;  4UM1 A;  4ILA A;  3RI5 A;  4QH1 A;  4Z90 A;  4QAB A;  4HQP A; 
#chains in the Genus database with same CATH homology
 4TWH A;  2QC1 B;  3EHZ A;  4UXU A;  4ZK1 A;  4TNV A;  3TLW A;  5HCJ A;  3SQ9 A;  3RQU A;  2XQ6 A;  2Y58 A;  4UM3 P;  5HEO A;  3UU6 A;  2PH9 A;  4BQT A;  2BYS A;  2BG9 A;  5FJV A;  1UV6 A;  4EZ1 A;  5AIN A;  4D01 A;  3GUA A;  2C9T A;  2Y56 A;  3T4M A;  2XQ7 A;  3WTJ A;  4UY2 A;  4XK9 A;  2BYQ A;  5AFJ A;  3UU5 A;  4ZK4 A;  3UQ7 A;  3WIP A;  3PEO A;  4UM3 A;  3ZDG A;  5HEU A;  2Y57 A;  2XQ8 A;  3PMZ A;  3UUB A;  3SIO A;  2XYT A;  2BR8 A;  4TWF A;  3P4W A;  3C79 A;  3TLT A;  3WTL A;  5LXB A;  4HFB A;  2X00 D;  3UU3 A;  3WTI A;  2XNT A;  5TVC A;  5BRX A;  5J5H A;  3ZDH A;  4LML A;  4BFQ A;  5IUX A;  2X00 A;  3RQW A;  3U8N A;  2PGZ A;  5L4H A;  3U8J A;  2YN6 A;  1I9B A;  2BYN A;  3RIF A;  2WNL A;  3TLS A;  3WTO A;  3WTN A;  4A98 A;  4IL9 A;  4Z91 A;  2BG9 C;  4QAC A;  4ALX A;  2XYS A;  2WNC A;  3JAD A;  4PIR A;  5CFB A;  5LG3 A;  3EAM A;  2BR7 A;  2Y7Y A;  5SYO A;  4FRR A;  5KE4 A;  2XZ6 A;  2YKS A;  3EI0 A;  2UZ6 A;  4HFD A;  3UU4 A;  2XQ3 A;  4ZRU A;  3U8K A;  2XZ5 A;  3TLV A;  4ILB A;  4DBM A;  4ZZC A;  4HFH A;  4A97 A;  2YMD A;  4AFT A;  3RHW A;  3UU8 A;  5BP0 A;  2VL0 A;  5AFL A;  4WV9 A;  4HFE A;  4HFC A;  2XQ9 A;  5AFN A;  5J5G A;  3JAF A;  4COF A;  3WTH A;  2W8F A;  5AFM B;  1UX2 A;  5J0Z A;  3RIA A;  5HCM A;  2XQ4 A;  5J5F A;  4QH5 A;  1UW6 A;  4IL4 A;  2WN9 A;  3U8L A;  3WTK A;  3U8M A;  5BW2 A;  4AFH A;  4ZJT A;  2BYP A;  2WNJ A;  2BG9 E;  3SQ6 A;  4LMJ A;  2YOE A;  2BG9 B;  4LMK A;  4ZR6 A;  4XHE A;  4ZZB A;  5JME A;  2XQ5 A;  2XNV A;  3UQ4 A;  2WZY A;  5L47 A;  2XNU A;  2W8G A;  4TNW A;  4UM3 S;  5AFM A;  3IGQ A;  5HEH A;  5J5I A;  5CO5 A;  3ZKR A;  5HEG A;  4F8H A;  4IRE A;  4QAA A;  4QH4 A;  4AFG A;  3P50 A;  2XQA A;  5AFK A;  2Y54 A;  3C84 A;  5KZU A;  4B5D A;  5AFH A;  4NZB A;  3SH1 A;  4HFI A;  2ZJU A;  2ZJV A;  3TLU A;  4NPP A;  5L4E A;  2YME A;  2BYR A;  4ILC A;  4ZJS A;  3JAE A;  3LSV A;  2BJ0 A;  4X5T A;  4TWD A;  5HEJ A;  3WTM A;  4UM1 A;  4ILA A;  3RI5 A;  4QH1 A;  4Z90 A;  4QAB A;  4HQP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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