3WTNA

Crystal structure of lymnaea stagnalis acetylcholine binding protein complexed with desnitro-imidacloprid
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
208
structure length
208
Chain Sequence
AEAADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions
pubmed doi rcsb
molecule keywords Acetylcholine-binding protein
molecule tags Signaling protein
source organism Lymnaea stagnalis
total genus 48
structure length 208
sequence length 208
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2014-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 3wtnA00
3P50A 4ZZBA 3U8LA 5BRXA 5LXBA 3WTOA 5KZUA 2XQAA 1UV6A 4PIRA 2ZJVA 3PMZA 5AFMB 4ZK1A 4AFTA 2XNVA 3UU3A 4IL9A 2Y57A 4ZK4A 3WTKA 4WV9A 2XQ4A 4XHEA 4HFDA 1UW6A 4FRRA 3WTIA 3JAEA 4ALXA 4XK9A 2BR8A 2W8FA 4F8HA 5AFNA 4HQPA 5LG3A 2BYSA 2ZJUA 3TLTA 4LMJA 2BG9E 4Z90A 5AFJA 4NPPA 3U8JA 5J5FA 2WNCA 2X00D 5BW2A 5J5HA 2YKSA 4QH1A 2BYRA 3EI0A 2XQ3A 2PH9A 4QH5A 4TWFA 5AINA 2XNUA 2WNJA 3TLSA 2XZ6A 3TLVA 3C79A 5AFLA 5J5IA 5J0ZA 3U8KA 2XYSA 3RQWA 2YMDA 4AFHA 5SYOA 3ZDGA 2VL0A 5L4HA 3EAMA 5IUXA 5HEJA 5CO5A 4HFIA 5HEUA 4LMKA 2XYTA 2YN6A 4UY2A 3UQ4A 4A98A 5HCJA 4UM1A 3ZDHA 3UU5A 3EHZA 4B5DA 5HEHA 2XQ5A 2XQ9A 4IL4A 2XQ6A 3WTMA 2BG9A 3TLWA 4LMLA 3RIAA 4DBMA 4TWDA 4TNVA 2XQ7A 4QACA 5AFHA 3UU6A 3GUAA 2BYNA 4Z91A 4D01A 5TVCA 3U8MA 2BJ0A 3UUBA 4COFA 3IGQA 3UU4A 3WTJA 4UM3A 4UM3S 3U8NA 3UQ7A 5AFKA 3SIOA 4AFGA 2YMEA 3WTHA 3RHWA 2C9TA 2BYPA 5JMEA 5FJVA 3WIPA 2BYQA 5KE4A 2WZYA 3T4MA 5HEOA 4ILCA 5J5GA 2Y58A 4BFQA 4ZR6A 2BG9C 2BR7A 4QH4A 4IREA 3SQ6A 4ZRUA 2XQ8A 1I9BA 5HEGA 3WTNA 4BQTA 4HFCA 4A97A 4HFEA 3UU8A 2X00A 2Y7YA 2WN9A 3LSVA 4ZJTA 3PEOA 4EZ1A 3RIFA 4HFHA 3RI5A 3TLUA 4UXUA 4QABA 2XZ5A 2PGZA 3C84A 2UZ6A 2Y56A 2XNTA 4TNWA 2BG9B 2YOEA 4NZBA 2W8GA 4X5TA 4TWHA 3JAFA 3WTLA 5AFMA 4ZJSA 3SH1A 5L47A 5BP0A 2WNLA 1UX2A 4ILAA 2Y54A 4QAAA 5L4EA 4HFBA 4UM3P 5HCMA 3RQUA 3JADA 3P4WA 4ILBA 3SQ9A 5CFBA 3ZKRA 4ZZCA 2QC1B
chains in the Genus database with same CATH superfamily
3P50A 4ZZBA 3U8LA 5BRXA 5LXBA 3WTOA 5KZUA 2XQAA 1UV6A 4PIRA 2ZJVA 3PMZA 5AFMB 4ZK1A 4AFTA 2XNVA 3UU3A 4IL9A 2Y57A 4ZK4A 3WTKA 4WV9A 2XQ4A 4XHEA 4HFDA 1UW6A 4FRRA 3WTIA 3JAEA 4ALXA 4XK9A 2BR8A 2W8FA 4F8HA 5AFNA 4HQPA 5LG3A 2BYSA 2ZJUA 3TLTA 4LMJA 2BG9E 4Z90A 5AFJA 4NPPA 3U8JA 5J5FA 2WNCA 2X00D 5BW2A 5J5HA 2YKSA 4QH1A 2BYRA 3EI0A 2XQ3A 2PH9A 4QH5A 4TWFA 5AINA 2XNUA 2WNJA 3TLSA 2XZ6A 3TLVA 3C79A 5AFLA 5J5IA 5J0ZA 3U8KA 2XYSA 3RQWA 2YMDA 4AFHA 5SYOA 3ZDGA 2VL0A 5L4HA 3EAMA 5IUXA 5HEJA 5CO5A 4HFIA 5HEUA 4LMKA 2XYTA 2YN6A 4UY2A 3UQ4A 4A98A 5HCJA 4UM1A 3ZDHA 3UU5A 3EHZA 4B5DA 5HEHA 2XQ5A 2XQ9A 4IL4A 2XQ6A 3WTMA 2BG9A 3TLWA 4LMLA 3RIAA 4DBMA 4TWDA 4TNVA 2XQ7A 4QACA 5AFHA 3UU6A 3GUAA 2BYNA 4Z91A 4D01A 5TVCA 3U8MA 2BJ0A 3UUBA 4COFA 3IGQA 3UU4A 3WTJA 4UM3A 4UM3S 3U8NA 3UQ7A 5AFKA 3SIOA 4AFGA 2YMEA 3WTHA 3RHWA 2C9TA 2BYPA 5JMEA 5FJVA 3WIPA 2BYQA 5KE4A 2WZYA 3T4MA 5HEOA 4ILCA 5J5GA 2Y58A 4BFQA 4ZR6A 2BG9C 2BR7A 4QH4A 4IREA 3SQ6A 4ZRUA 2XQ8A 1I9BA 5HEGA 3WTNA 4BQTA 4HFCA 4A97A 4HFEA 3UU8A 2X00A 2Y7YA 2WN9A 3LSVA 4ZJTA 3PEOA 4EZ1A 3RIFA 4HFHA 3RI5A 3TLUA 4UXUA 4QABA 2XZ5A 2PGZA 3C84A 2UZ6A 2Y56A 2XNTA 4TNWA 2BG9B 2YOEA 4NZBA 2W8GA 4X5TA 4TWHA 3JAFA 3WTLA 5AFMA 4ZJSA 3SH1A 5L47A 5BP0A 2WNLA 1UX2A 4ILAA 2Y54A 4QAAA 5L4EA 4HFBA 4UM3P 5HCMA 3RQUA 3JADA 3P4WA 4ILBA 3SQ9A 5CFBA 3ZKRA 4ZZCA 2QC1B
chains in the Genus database with same CATH topology
3P50A 4ZZBA 3U8LA 5BRXA 5LXBA 3WTOA 5KZUA 2XQAA 1UV6A 4PIRA 2ZJVA 3PMZA 5AFMB 4ZK1A 4AFTA 2XNVA 3UU3A 4IL9A 2Y57A 4ZK4A 3WTKA 4WV9A 2XQ4A 4XHEA 4HFDA 1UW6A 4FRRA 3WTIA 3JAEA 4ALXA 4XK9A 2BR8A 2W8FA 4F8HA 5AFNA 4HQPA 5LG3A 2BYSA 2ZJUA 3TLTA 4LMJA 2BG9E 4Z90A 5AFJA 4NPPA 3U8JA 5J5FA 2WNCA 2X00D 5BW2A 5J5HA 2YKSA 4QH1A 2BYRA 3EI0A 2XQ3A 2PH9A 4QH5A 4TWFA 5AINA 2XNUA 2WNJA 3TLSA 2XZ6A 3TLVA 3C79A 5AFLA 5J5IA 5J0ZA 3U8KA 2XYSA 3RQWA 2YMDA 4AFHA 5SYOA 3ZDGA 2VL0A 5L4HA 3EAMA 5IUXA 5HEJA 5CO5A 4HFIA 5HEUA 4LMKA 2XYTA 2YN6A 4UY2A 3UQ4A 4A98A 5HCJA 4UM1A 3ZDHA 3UU5A 3EHZA 4B5DA 5HEHA 2XQ5A 2XQ9A 4IL4A 2XQ6A 3WTMA 2BG9A 3TLWA 4LMLA 3RIAA 4DBMA 4TWDA 4TNVA 2XQ7A 4QACA 5AFHA 3UU6A 3GUAA 2BYNA 4Z91A 4D01A 5TVCA 3U8MA 2BJ0A 3UUBA 4COFA 3IGQA 3UU4A 3WTJA 4UM3A 4UM3S 3U8NA 3UQ7A 5AFKA 3SIOA 4AFGA 2YMEA 3WTHA 3RHWA 2C9TA 2BYPA 5JMEA 5FJVA 3WIPA 2BYQA 5KE4A 2WZYA 3T4MA 5HEOA 4ILCA 5J5GA 2Y58A 4BFQA 4ZR6A 2BG9C 2BR7A 4QH4A 4IREA 3SQ6A 4ZRUA 2XQ8A 1I9BA 5HEGA 3WTNA 4BQTA 4HFCA 4A97A 4HFEA 3UU8A 2X00A 2Y7YA 2WN9A 3LSVA 4ZJTA 3PEOA 4EZ1A 3RIFA 4HFHA 3RI5A 3TLUA 4UXUA 4QABA 2XZ5A 2PGZA 3C84A 2UZ6A 2Y56A 2XNTA 4TNWA 2BG9B 2YOEA 4NZBA 2W8GA 4X5TA 4TWHA 3JAFA 3WTLA 5AFMA 4ZJSA 3SH1A 5L47A 5BP0A 2WNLA 1UX2A 4ILAA 2Y54A 4QAAA 5L4EA 4HFBA 4UM3P 5HCMA 3RQUA 3JADA 3P4WA 4ILBA 3SQ9A 5CFBA 3ZKRA 4ZZCA 2QC1B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P50 A;  4ZZB A;  3U8L A;  5BRX A;  5LXB A;  3WTO A;  5KZU A;  2XQA A;  1UV6 A;  4PIR A;  2ZJV A;  3PMZ A;  5AFM B;  4ZK1 A;  4AFT A;  2XNV A;  3UU3 A;  4IL9 A;  2Y57 A;  4ZK4 A;  3WTK A;  4WV9 A;  2XQ4 A;  4XHE A;  4HFD A;  1UW6 A;  4FRR A;  3WTI A;  3JAE A;  4ALX A;  4XK9 A;  2BR8 A;  2W8F A;  4F8H A;  5AFN A;  4HQP A;  5LG3 A;  2BYS A;  2ZJU A;  3TLT A;  4LMJ A;  2BG9 E;  4Z90 A;  5AFJ A;  4NPP A;  3U8J A;  5J5F A;  2WNC A;  2X00 D;  5BW2 A;  5J5H A;  2YKS A;  4QH1 A;  2BYR A;  3EI0 A;  2XQ3 A;  2PH9 A;  4QH5 A;  4TWF A;  5AIN A;  2XNU A;  2WNJ A;  3TLS A;  2XZ6 A;  3TLV A;  3C79 A;  5AFL A;  5J5I A;  5J0Z A;  3U8K A;  2XYS A;  3RQW A;  2YMD A;  4AFH A;  5SYO A;  3ZDG A;  2VL0 A;  5L4H A;  3EAM A;  5IUX A;  5HEJ A;  5CO5 A;  4HFI A;  5HEU A;  4LMK A;  2XYT A;  2YN6 A;  4UY2 A;  3UQ4 A;  4A98 A;  5HCJ A;  4UM1 A;  3ZDH A;  3UU5 A;  3EHZ A;  4B5D A;  5HEH A;  2XQ5 A;  2XQ9 A;  4IL4 A;  2XQ6 A;  3WTM A;  2BG9 A;  3TLW A;  4LML A;  3RIA A;  4DBM A;  4TWD A;  4TNV A;  2XQ7 A;  4QAC A;  5AFH A;  3UU6 A;  3GUA A;  2BYN A;  4Z91 A;  4D01 A;  5TVC A;  3U8M A;  2BJ0 A;  3UUB A;  4COF A;  3IGQ A;  3UU4 A;  3WTJ A;  4UM3 A;  4UM3 S;  3U8N A;  3UQ7 A;  5AFK A;  3SIO A;  4AFG A;  2YME A;  3WTH A;  3RHW A;  2C9T A;  2BYP A;  5JME A;  5FJV A;  3WIP A;  2BYQ A;  5KE4 A;  2WZY A;  3T4M A;  5HEO A;  4ILC A;  5J5G A;  2Y58 A;  4BFQ A;  4ZR6 A;  2BG9 C;  2BR7 A;  4QH4 A;  4IRE A;  3SQ6 A;  4ZRU A;  2XQ8 A;  1I9B A;  5HEG A;  3WTN A;  4BQT A;  4HFC A;  4A97 A;  4HFE A;  3UU8 A;  2X00 A;  2Y7Y A;  2WN9 A;  3LSV A;  4ZJT A;  3PEO A;  4EZ1 A;  3RIF A;  4HFH A;  3RI5 A;  3TLU A;  4UXU A;  4QAB A;  2XZ5 A;  2PGZ A;  3C84 A;  2UZ6 A;  2Y56 A;  2XNT A;  4TNW A;  2BG9 B;  2YOE A;  4NZB A;  2W8G A;  4X5T A;  4TWH A;  3JAF A;  3WTL A;  5AFM A;  4ZJS A;  3SH1 A;  5L47 A;  5BP0 A;  2WNL A;  1UX2 A;  4ILA A;  2Y54 A;  4QAA A;  5L4E A;  4HFB A;  4UM3 P;  5HCM A;  3RQU A;  3JAD A;  3P4W A;  4ILB A;  3SQ9 A;  5CFB A;  3ZKR A;  4ZZC A;  2QC1 B; 
#chains in the Genus database with same CATH topology
 3P50 A;  4ZZB A;  3U8L A;  5BRX A;  5LXB A;  3WTO A;  5KZU A;  2XQA A;  1UV6 A;  4PIR A;  2ZJV A;  3PMZ A;  5AFM B;  4ZK1 A;  4AFT A;  2XNV A;  3UU3 A;  4IL9 A;  2Y57 A;  4ZK4 A;  3WTK A;  4WV9 A;  2XQ4 A;  4XHE A;  4HFD A;  1UW6 A;  4FRR A;  3WTI A;  3JAE A;  4ALX A;  4XK9 A;  2BR8 A;  2W8F A;  4F8H A;  5AFN A;  4HQP A;  5LG3 A;  2BYS A;  2ZJU A;  3TLT A;  4LMJ A;  2BG9 E;  4Z90 A;  5AFJ A;  4NPP A;  3U8J A;  5J5F A;  2WNC A;  2X00 D;  5BW2 A;  5J5H A;  2YKS A;  4QH1 A;  2BYR A;  3EI0 A;  2XQ3 A;  2PH9 A;  4QH5 A;  4TWF A;  5AIN A;  2XNU A;  2WNJ A;  3TLS A;  2XZ6 A;  3TLV A;  3C79 A;  5AFL A;  5J5I A;  5J0Z A;  3U8K A;  2XYS A;  3RQW A;  2YMD A;  4AFH A;  5SYO A;  3ZDG A;  2VL0 A;  5L4H A;  3EAM A;  5IUX A;  5HEJ A;  5CO5 A;  4HFI A;  5HEU A;  4LMK A;  2XYT A;  2YN6 A;  4UY2 A;  3UQ4 A;  4A98 A;  5HCJ A;  4UM1 A;  3ZDH A;  3UU5 A;  3EHZ A;  4B5D A;  5HEH A;  2XQ5 A;  2XQ9 A;  4IL4 A;  2XQ6 A;  3WTM A;  2BG9 A;  3TLW A;  4LML A;  3RIA A;  4DBM A;  4TWD A;  4TNV A;  2XQ7 A;  4QAC A;  5AFH A;  3UU6 A;  3GUA A;  2BYN A;  4Z91 A;  4D01 A;  5TVC A;  3U8M A;  2BJ0 A;  3UUB A;  4COF A;  3IGQ A;  3UU4 A;  3WTJ A;  4UM3 A;  4UM3 S;  3U8N A;  3UQ7 A;  5AFK A;  3SIO A;  4AFG A;  2YME A;  3WTH A;  3RHW A;  2C9T A;  2BYP A;  5JME A;  5FJV A;  3WIP A;  2BYQ A;  5KE4 A;  2WZY A;  3T4M A;  5HEO A;  4ILC A;  5J5G A;  2Y58 A;  4BFQ A;  4ZR6 A;  2BG9 C;  2BR7 A;  4QH4 A;  4IRE A;  3SQ6 A;  4ZRU A;  2XQ8 A;  1I9B A;  5HEG A;  3WTN A;  4BQT A;  4HFC A;  4A97 A;  4HFE A;  3UU8 A;  2X00 A;  2Y7Y A;  2WN9 A;  3LSV A;  4ZJT A;  3PEO A;  4EZ1 A;  3RIF A;  4HFH A;  3RI5 A;  3TLU A;  4UXU A;  4QAB A;  2XZ5 A;  2PGZ A;  3C84 A;  2UZ6 A;  2Y56 A;  2XNT A;  4TNW A;  2BG9 B;  2YOE A;  4NZB A;  2W8G A;  4X5T A;  4TWH A;  3JAF A;  3WTL A;  5AFM A;  4ZJS A;  3SH1 A;  5L47 A;  5BP0 A;  2WNL A;  1UX2 A;  4ILA A;  2Y54 A;  4QAA A;  5L4E A;  4HFB A;  4UM3 P;  5HCM A;  3RQU A;  3JAD A;  3P4W A;  4ILB A;  3SQ9 A;  5CFB A;  3ZKR A;  4ZZC A;  2QC1 B; 
#chains in the Genus database with same CATH homology
 3P50 A;  4ZZB A;  3U8L A;  5BRX A;  5LXB A;  3WTO A;  5KZU A;  2XQA A;  1UV6 A;  4PIR A;  2ZJV A;  3PMZ A;  5AFM B;  4ZK1 A;  4AFT A;  2XNV A;  3UU3 A;  4IL9 A;  2Y57 A;  4ZK4 A;  3WTK A;  4WV9 A;  2XQ4 A;  4XHE A;  4HFD A;  1UW6 A;  4FRR A;  3WTI A;  3JAE A;  4ALX A;  4XK9 A;  2BR8 A;  2W8F A;  4F8H A;  5AFN A;  4HQP A;  5LG3 A;  2BYS A;  2ZJU A;  3TLT A;  4LMJ A;  2BG9 E;  4Z90 A;  5AFJ A;  4NPP A;  3U8J A;  5J5F A;  2WNC A;  2X00 D;  5BW2 A;  5J5H A;  2YKS A;  4QH1 A;  2BYR A;  3EI0 A;  2XQ3 A;  2PH9 A;  4QH5 A;  4TWF A;  5AIN A;  2XNU A;  2WNJ A;  3TLS A;  2XZ6 A;  3TLV A;  3C79 A;  5AFL A;  5J5I A;  5J0Z A;  3U8K A;  2XYS A;  3RQW A;  2YMD A;  4AFH A;  5SYO A;  3ZDG A;  2VL0 A;  5L4H A;  3EAM A;  5IUX A;  5HEJ A;  5CO5 A;  4HFI A;  5HEU A;  4LMK A;  2XYT A;  2YN6 A;  4UY2 A;  3UQ4 A;  4A98 A;  5HCJ A;  4UM1 A;  3ZDH A;  3UU5 A;  3EHZ A;  4B5D A;  5HEH A;  2XQ5 A;  2XQ9 A;  4IL4 A;  2XQ6 A;  3WTM A;  2BG9 A;  3TLW A;  4LML A;  3RIA A;  4DBM A;  4TWD A;  4TNV A;  2XQ7 A;  4QAC A;  5AFH A;  3UU6 A;  3GUA A;  2BYN A;  4Z91 A;  4D01 A;  5TVC A;  3U8M A;  2BJ0 A;  3UUB A;  4COF A;  3IGQ A;  3UU4 A;  3WTJ A;  4UM3 A;  4UM3 S;  3U8N A;  3UQ7 A;  5AFK A;  3SIO A;  4AFG A;  2YME A;  3WTH A;  3RHW A;  2C9T A;  2BYP A;  5JME A;  5FJV A;  3WIP A;  2BYQ A;  5KE4 A;  2WZY A;  3T4M A;  5HEO A;  4ILC A;  5J5G A;  2Y58 A;  4BFQ A;  4ZR6 A;  2BG9 C;  2BR7 A;  4QH4 A;  4IRE A;  3SQ6 A;  4ZRU A;  2XQ8 A;  1I9B A;  5HEG A;  3WTN A;  4BQT A;  4HFC A;  4A97 A;  4HFE A;  3UU8 A;  2X00 A;  2Y7Y A;  2WN9 A;  3LSV A;  4ZJT A;  3PEO A;  4EZ1 A;  3RIF A;  4HFH A;  3RI5 A;  3TLU A;  4UXU A;  4QAB A;  2XZ5 A;  2PGZ A;  3C84 A;  2UZ6 A;  2Y56 A;  2XNT A;  4TNW A;  2BG9 B;  2YOE A;  4NZB A;  2W8G A;  4X5T A;  4TWH A;  3JAF A;  3WTL A;  5AFM A;  4ZJS A;  3SH1 A;  5L47 A;  5BP0 A;  2WNL A;  1UX2 A;  4ILA A;  2Y54 A;  4QAA A;  5L4E A;  4HFB A;  4UM3 P;  5HCM A;  3RQU A;  3JAD A;  3P4W A;  4ILB A;  3SQ9 A;  5CFB A;  3ZKR A;  4ZZC A;  2QC1 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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