3WV1A

Crystal structure of the catalytic domain of mmp-13 complexed with 4-(2-((6-fluoro-2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydroquinazolin-5-yl)oxy)ethyl)benzoic acid
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
170
structure length
170
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Collagenase 3
publication title Discovery of novel, highly potent, and selective quinazoline-2-carboxamide-based matrix metalloproteinase (MMP)-13 inhibitors without a zinc binding group using a structure-based design approach
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 46
structure length 170
sequence length 170
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2014-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3wv1A00
4PKSA 1HV5A 4A7BA 2RJPA 3B8ZA 2JT6A 3OHLA 1JAQA 4WZVA 1QJJA 1MMRA 3EDIA 3EDHA 2CLTA 1SRPA 5D1TA 1ZTQA 3B92A 3TS4A 1MNCA 2Z2DA 3LJTA 3LJZA 4H2EA 1D8FA 4PKQA 1BIWA 3DPFA 4WK7A 2OW0A 3VTGA 3KEKA 4WKIA 2E3XA 4H76A 1PWPA 4IUWA 3EHYA 1ASTA 1OM6A 1BKCE 1QJIA 3UVCA 1AKLA 2Y6CA 1XFWA 2OY2A 3LIRA 1RM8A 4FU4A 5I4OA 2QPJA 3I7IA 5D3CA 1G9KA 1I1IP 1CXVA 1BKCI 1HFCA 2OVZA 4L19A 1GE7A 1PWWA 1OM7A 4XCTA 1IACA 1R1HA 1JK3A 3KMEA 4XM6A 1BZSA 1ZVXA 2D1OA 4I03A 3TSKA 5CZMA 1GO7P 1S4BP 3KWVC 3OHOA 2OZRA 2OY4A 4DPEA 3F16A 1IAEA 3KEJA 3USNA 1IADA 4FXYP 4AYKA 1O0TA 1AF0A 1CIZA 2V4BA 2JSDA 3I7GA 1JIZA 3LE9A 2OXZA 1SU3A 1WNIA 2W15A 1OO9A 3K7LA 1D5JA 2RJQA 1FLSA 1ROSA 4ON1A 2I47A 1ZS0A 3O2XA 3ELMA 4EFSA 2A8HA 4PKVA 1BUVM 2MZHA 4JQGA 3RTTA 2MLRA 1USNA 4AUOA 1JIWP 1IAGA 5L79A 3BA0A 3LMCA 1Y93A 966CA 1Q3AA 5I12A 1UTZA 2AIGP 1G05A 1KUHA 3DWBA 1KBCA 1KUIA 5BPAA 1QIAA 3WV3A 1L6JA 3KHIA 2JNPA 3LEAA 3HYGA 2W12A 1XUDA 4L6TA 1G12A 4GUYA 4DV8A 3HBUP 2K2GA 1ZXVA 4AIGA 4CTHA 2CKIA 2W0DA 1ZP5A 2OW1A 3KMCA 3NX7A 3RTSA 1QIBA 2OXUA 1EB6A 1J7NA 2HU6A 4ZR5A 2D1NA 2X3CA 2ERQA 3F18A 2EROA 2N8RA 3E8RA 2DW0A 3TT4A 4G0DA 456CA 5LABA 1FM1A 3LK8A 4JA1A 2J83A 1HOVA 1GE5A 3HY7A 5D2BA 1BSWA 1G4KA 4H49A 4H1QA 1YQYA 5I3MA 2YIGA 2ERPA 2OXWA 3F15A 1SATA 4H82A 1BQOA 1K7GA 4R3VA 1ATLA 1JAOA 3F19A 1EAKA 1JKYA 1GKDA 1GXDA 1UEAA 3EDZA 2X3AA 2DW1A 4GR8A 4GWNA 1O0QA 2YB9A 5B5OA 3CKIA 1R1JA 3LUMA 2Y6DA 2TCLA 1GE6A 4FVLA 3KRYA 5D1SA 1CGLA 2MLSA 1R54A 3AYUA 2WOAA 4IN9A 5I2ZA 1XFXA 2USNA 1Z3JA 1A86A 1DMTA 2W14A 1QICA 1UMTA 5CUHA 4PKRA 4XM8A 4PKWA 1IABA 1C8TA 3LIKA 3V96B 1MMPA 1JJ9A 4IJOA 3DL1A 3GBOA 2KRJA 1SMPA 1JH1A 1Y0VA 3AYKA 4JIJA 1HTDA 2W13A 2XS3A 1QUAA 1B3DA 4FXQA 2OW2A 2MZEA 3WV2A 3L0TA 1PWQA 1JAPA 3ZUKA 1D7XA 2XS4A 3EHXA 1R1IA 3LUNA 5I0LA 4GWMA 1R55A 4I35A 5JMYA 1YCMA 3MA2A 1BQQM 2DDFA 3ZVSA 1PWVA 1KAPP 4GQLA 3DPEA 4J4MA 3TVCA 3F17A 4XBHA 1AYKA 3VI1A 2X7MA 3AIGA 1DTHA 3Q2GA 3LQ0A 2MZIA 1C7KA 1XURA 3LGPA 1MMQA 3P24A 3EWJA 4G9LA 4GR3A 3ZXHA 2SRTA 4XM7A 3HY9A 2FV9A 3B2ZA 4L63A 1CQRA 4DD8A 5BOTA 5I43A 1ND1A 1CK7A 1JANA 4H3XA 1A85A 5H8XA 1KUGA 4DF9A 1ZXCA 2OW9A 4GF1A 1MMBA 3HDBA 3P1VA 830CA 1CAQA 1OM8A 1D8MA 1C3IA 2J0TA 1I73A 3HB2P 4H84A 1EUBA 3KECA 2WO8A 3HDAP 3N2UA 4JPAA 4HMAA 3O64A 5L7FA 1OMJA 3DNGA 4PKTA 2JT5A 3EDGA 1XFYA 1G49A 1HFSA 2X3BA 5D7WA 3G5CA 1KUKA 2OI0A 3Q2HA 5CXAA 1YP1A 2E2DA 3HBVP 3F1AA 1RMZA 1B8YA 4WF6A 1KUFA 2POJA 4A3WA 1UMSA 1OS2A 1XFUA 4GR0A 1XFZA 2O36A 1CGFA 2FV5A 2K9CA 4PKUA 1YOUA 1SLNA 2PJTA 5D1UA 3G42A 2WO9A 1FBLA 4WKEA 2O3EA 2AYKA 1BKCA 1OS9A 1IAAA 1I76A 1BUDA 1Y8JA 2DW2A 5BOYA 3WV1A 2DDYA 1BM6A 1K7IA 3U1RA 1SLMA 1PWUA 3DSLA 1XFVA 2L0RA 4H30A 2JIHA 4HX3A 1K7QA 3SHIA 4ILWD 1XUCA 1H71P 1HY7A 3LJGA 2OVXA 3LKAA 1GO8P 4AXQA 3K7NA 1UTTA 1CGEA 4Q1LA 1GKCA 3LQBA 4QKZA 3L0VA 3LILA 4JP4A 3N2VA 5B5PA
chains in the Genus database with same CATH superfamily
4PKSA 1HV5A 4A7BA 2RJPA 3B8ZA 2JT6A 3OHLA 1JAQA 4WZVA 1QJJA 1MMRA 3EDIA 3EDHA 2CLTA 1TVIA 1SRPA 5D1TA 1ZTQA 3B92A 3TS4A 1MNCA 2Z2DA 3LJTA 3LJZA 4H2EA 1D8FA 4PKQA 1BIWA 3DPFA 4WK7A 2OW0A 3VTGA 3KEKA 4WKIA 2E3XA 4H76A 1PWPA 4IUWA 3EHYA 1ASTA 1OM6A 1BKCE 1QJIA 3UVCA 1AKLA 2Y6CA 1XFWA 2OY2A 3LIRA 1RM8A 4FU4A 5I4OA 2QPJA 3I7IA 5D3CA 1G9KA 1I1IP 1CXVA 1BKCI 1HFCA 2OVZA 4L19A 1GE7A 1PWWA 1OM7A 4XCTA 1IACA 1R1HA 1JK3A 3KMEA 4XM6A 1BZSA 1ZVXA 2D1OA 4I03A 3TSKA 5CZMA 1GO7P 1S4BP 3KWVC 3OHOA 2OZRA 3DTEA 2OY4A 4DPEA 3F16A 1IAEA 3KEJA 3USNA 1IADA 4FXYP 4AYKA 1O0TA 1AF0A 1CIZA 2V4BA 2JSDA 3I7GA 1JIZA 3LE9A 2OXZA 1SU3A 1WNIA 2W15A 1OO9A 3K7LA 1D5JA 2RJQA 1FLSA 1ROSA 4ON1A 2I47A 1ZS0A 3O2XA 3ELMA 4EFSA 2A8HA 4PKVA 1BUVM 2MZHA 4JQGA 3RTTA 2MLRA 1USNA 4AUOA 1JIWP 1IAGA 5L79A 3BA0A 3LMCA 1Y93A 966CA 1Q3AA 5I12A 1UTZA 2AIGP 1G05A 1KUHA 2YUFA 3DWBA 1KBCA 1KUIA 5BPAA 1QIAA 3WV3A 1L6JA 3KHIA 2JNPA 3LEAA 3HYGA 2W12A 1XUDA 4L6TA 1G12A 4GUYA 4DV8A 3HBUP 2K2GA 1ZXVA 4AIGA 4CTHA 2CKIA 2W0DA 1ZP5A 2OW1A 3KMCA 3NX7A 3RTSA 1QIBA 2OXUA 1EB6A 1J7NA 2HU6A 4ZR5A 2D1NA 2X3CA 2ERQA 3F18A 2EROA 2N8RA 3E8RA 2DW0A 3TT4A 4G0DA 456CA 5LABA 1FM1A 3LK8A 4JA1A 2J83A 1HOVA 1GE5A 3HY7A 5D2BA 1BSWA 1G4KA 4H49A 4H1QA 1YQYA 5I3MA 2YIGA 2ERPA 2OXWA 3F15A 1SATA 4H82A 1BQOA 1K7GA 4R3VA 1ATLA 1JAOA 3F19A 1EAKA 1JKYA 1GKDA 1GXDA 1UEAA 3EDZA 2X3AA 2DW1A 4GR8A 4GWNA 1O0QA 2YB9A 5B5OA 3CKIA 1R1JA 3DTIA 3LUMA 2Y6DA 2TCLA 1GE6A 4FVLA 3KRYA 5D1SA 1CGLA 2MLSA 1R54A 3DTKA 3AYUA 2WOAA 4IN9A 5I2ZA 1XFXA 2USNA 1Z3JA 1A86A 1DMTA 2W14A 1QICA 1UMTA 5CUHA 4PKRA 4XM8A 4PKWA 1IABA 1C8TA 3LIKA 3V96B 1MMPA 1JJ9A 4IJOA 3DL1A 3GBOA 2KRJA 1SMPA 1JH1A 1Y0VA 3AYKA 4JIJA 1HTDA 2W13A 2XS3A 1QUAA 1B3DA 4FXQA 2OW2A 2MZEA 3WV2A 3L0TA 1PWQA 1JAPA 3ZUKA 1D7XA 2XS4A 3EHXA 1R1IA 3LUNA 5I0LA 4GWMA 1R55A 4I35A 5JMYA 4L7AA 1YCMA 3MA2A 1BQQM 2DDFA 3ZVSA 1PWVA 1KAPP 4GQLA 3DPEA 4J4MA 3TVCA 3F17A 4XBHA 1AYKA 3VI1A 2X7MA 3AIGA 1DTHA 3Q2GA 3LQ0A 2MZIA 1C7KA 1XURA 3LGPA 1MMQA 3P24A 3EWJA 4G9LA 4GR3A 3ZXHA 2SRTA 4XM7A 3HY9A 2FV9A 3B2ZA 4L63A 1CQRA 4DD8A 5BOTA 1OZ9A 5I43A 1ND1A 1CK7A 1JANA 4H3XA 1A85A 5H8XA 1KUGA 4DF9A 1ZXCA 2OW9A 4GF1A 1MMBA 3HDBA 3P1VA 830CA 1CAQA 1OM8A 1D8MA 1C3IA 2J0TA 1I73A 3HB2P 4H84A 1EUBA 3KECA 2WO8A 3HDAP 3N2UA 4JPAA 4HMAA 3O64A 5L7FA 1OMJA 3DNGA 4PKTA 2JT5A 3EDGA 1XFYA 1G49A 1HFSA 2X3BA 1XAXA 5D7WA 3G5CA 1KUKA 2OI0A 3Q2HA 5CXAA 1YP1A 2E2DA 3HBVP 3F1AA 1RMZA 1B8YA 4WF6A 1KUFA 2POJA 4A3WA 1UMSA 1OS2A 1XFUA 4GR0A 1XFZA 2O36A 1XM5A 1CGFA 2FV5A 2K9CA 4PKUA 1YOUA 1SLNA 2PJTA 5D1UA 3G42A 2WO9A 1FBLA 4WKEA 2O3EA 2AYKA 1BKCA 1OS9A 1IAAA 1I76A 1BUDA 1Y8JA 2DW2A 5BOYA 3WV1A 2DDYA 1BM6A 1K7IA 3U1RA 1SLMA 1PWUA 3DSLA 1XFVA 2L0RA 4H30A 2JIHA 4HX3A 1K7QA 3SHIA 4ILWD 1XUCA 1H71P 1HY7A 3LJGA 2OVXA 3LKAA 1GO8P 4AXQA 3K7NA 1UTTA 1CGEA 4Q1LA 1GKCA 3LQBA 4QKZA 3L0VA 3LILA 4JP4A 3N2VA 5B5PA
chains in the Genus database with same CATH topology
4PKSA 1HV5A 4A7BA 2RJPA 3B8ZA 2JT6A 3OHLA 1JAQA 4WZVA 1QJJA 1MMRA 3EDIA 3EDHA 2CLTA 1SRPA 5D1TA 1ZTQA 3B92A 3TS4A 1MNCA 2Z2DA 3LJTA 3LJZA 4H2EA 1D8FA 4PKQA 1BIWA 3DPFA 4WK7A 2OW0A 3VTGA 3KEKA 4WKIA 2E3XA 4H76A 1PWPA 4IUWA 3EHYA 1ASTA 1OM6A 1BKCE 1QJIA 3UVCA 1AKLA 2Y6CA 1XFWA 2OY2A 3LIRA 1RM8A 4FU4A 5I4OA 2QPJA 3I7IA 5D3CA 1G9KA 1I1IP 1CXVA 1BKCI 1HFCA 2OVZA 4L19A 1GE7A 1PWWA 1OM7A 4XCTA 1IACA 1R1HA 1JK3A 3KMEA 4XM6A 1BZSA 1ZVXA 2D1OA 4I03A 3TSKA 5CZMA 1GO7P 1S4BP 3KWVC 3OHOA 2OZRA 3DTEA 2OY4A 4DPEA 3F16A 1IAEA 3KEJA 3USNA 1IADA 4FXYP 4AYKA 1O0TA 1AF0A 1CIZA 2V4BA 2JSDA 3I7GA 1JIZA 3LE9A 2OXZA 1SU3A 1WNIA 2W15A 1OO9A 3K7LA 1D5JA 2RJQA 1FLSA 1ROSA 4ON1A 2I47A 1ZS0A 3O2XA 3ELMA 4EFSA 2A8HA 4PKVA 1BUVM 2MZHA 4JQGA 3RTTA 2MLRA 1USNA 4AUOA 1JIWP 1IAGA 5L79A 3BA0A 3LMCA 1Y93A 966CA 1Q3AA 5I12A 1UTZA 2AIGP 1G05A 1KUHA 2YUFA 3DWBA 1KBCA 1KUIA 5BPAA 1QIAA 3WV3A 1L6JA 3KHIA 2JNPA 3LEAA 3HYGA 2W12A 1XUDA 4L6TA 1G12A 4GUYA 4DV8A 3HBUP 2K2GA 1ZXVA 4AIGA 4CTHA 2CKIA 2W0DA 1ZP5A 2OW1A 3KMCA 3NX7A 3RTSA 1QIBA 2OXUA 1EB6A 1J7NA 2HU6A 4ZR5A 2D1NA 2X3CA 2ERQA 3F18A 2EROA 2N8RA 3E8RA 2DW0A 3TT4A 4G0DA 456CA 5LABA 1FM1A 3LK8A 4JA1A 2J83A 1HOVA 1GE5A 3HY7A 5D2BA 1BSWA 1G4KA 4H49A 4H1QA 1YQYA 5I3MA 2YIGA 2ERPA 2OXWA 3F15A 1SATA 4H82A 1BQOA 1K7GA 4R3VA 1ATLA 1JAOA 3F19A 1EAKA 1JKYA 1GKDA 1GXDA 1UEAA 3EDZA 2X3AA 2DW1A 4GR8A 4GWNA 1O0QA 2YB9A 5B5OA 3CKIA 1R1JA 3DTIA 3LUMA 2Y6DA 2TCLA 1GE6A 4FVLA 3KRYA 5D1SA 1CGLA 2MLSA 1R54A 3DTKA 3AYUA 2WOAA 4IN9A 5I2ZA 1XFXA 2USNA 1Z3JA 1A86A 1DMTA 2W14A 1QICA 1UMTA 5CUHA 4PKRA 4XM8A 4PKWA 1IABA 1C8TA 3LIKA 3V96B 1MMPA 1JJ9A 4IJOA 3DL1A 3GBOA 2KRJA 1SMPA 1JH1A 1Y0VA 3AYKA 4JIJA 1HTDA 2W13A 2XS3A 1QUAA 1B3DA 4FXQA 2OW2A 2MZEA 3WV2A 3L0TA 1PWQA 1JAPA 3ZUKA 1D7XA 2XS4A 3EHXA 1R1IA 3LUNA 5I0LA 4GWMA 1R55A 4I35A 5JMYA 4L7AA 1YCMA 3MA2A 1BQQM 2DDFA 3ZVSA 1PWVA 1KAPP 4GQLA 3DPEA 4J4MA 3TVCA 3F17A 4XBHA 1AYKA 3VI1A 2X7MA 3AIGA 1DTHA 3Q2GA 3LQ0A 2MZIA 1C7KA 1XURA 3LGPA 1MMQA 3P24A 3EWJA 4G9LA 4GR3A 3ZXHA 2SRTA 4XM7A 3HY9A 2FV9A 3B2ZA 4L63A 1CQRA 4DD8A 5BOTA 5I43A 1ND1A 1CK7A 1JANA 4H3XA 1A85A 5H8XA 1KUGA 4DF9A 1ZXCA 2OW9A 4GF1A 1MMBA 3HDBA 3P1VA 830CA 1CAQA 1OM8A 1D8MA 1C3IA 2J0TA 1I73A 3HB2P 4H84A 1EUBA 3KECA 2WO8A 3HDAP 3N2UA 4JPAA 4HMAA 3O64A 5L7FA 1OMJA 3DNGA 4PKTA 2JT5A 3EDGA 1XFYA 1G49A 1HFSA 2X3BA 5D7WA 3G5CA 1KUKA 2OI0A 3Q2HA 5CXAA 1YP1A 2E2DA 3HBVP 3F1AA 1RMZA 1B8YA 4WF6A 1KUFA 2POJA 4A3WA 1UMSA 1OS2A 1XFUA 4GR0A 1XFZA 2O36A 1CGFA 2FV5A 2K9CA 4PKUA 1YOUA 1SLNA 2PJTA 5D1UA 3G42A 2WO9A 1FBLA 4WKEA 2O3EA 2AYKA 1BKCA 1OS9A 1IAAA 1I76A 1BUDA 1Y8JA 2DW2A 5BOYA 3WV1A 2DDYA 1BM6A 1K7IA 3U1RA 1SLMA 1PWUA 3DSLA 1XFVA 2L0RA 4H30A 2JIHA 4HX3A 1K7QA 3SHIA 4ILWD 1XUCA 1H71P 1HY7A 3LJGA 2OVXA 3LKAA 1GO8P 4AXQA 3K7NA 1UTTA 1CGEA 4Q1LA 1GKCA 3LQBA 4QKZA 3L0VA 3LILA 4JP4A 3N2VA 5B5PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PKS A;  1HV5 A;  4A7B A;  2RJP A;  3B8Z A;  2JT6 A;  3OHL A;  1JAQ A;  4WZV A;  1QJJ A;  1MMR A;  3EDI A;  3EDH A;  2CLT A;  1SRP A;  5D1T A;  1ZTQ A;  3B92 A;  3TS4 A;  1MNC A;  2Z2D A;  3LJT A;  3LJZ A;  4H2E A;  1D8F A;  4PKQ A;  1BIW A;  3DPF A;  4WK7 A;  2OW0 A;  3VTG A;  3KEK A;  4WKI A;  2E3X A;  4H76 A;  1PWP A;  4IUW A;  3EHY A;  1AST A;  1OM6 A;  1BKC E;  1QJI A;  3UVC A;  1AKL A;  2Y6C A;  1XFW A;  2OY2 A;  3LIR A;  1RM8 A;  4FU4 A;  5I4O A;  2QPJ A;  3I7I A;  5D3C A;  1G9K A;  1I1I P;  1CXV A;  1BKC I;  1HFC A;  2OVZ A;  4L19 A;  1GE7 A;  1PWW A;  1OM7 A;  4XCT A;  1IAC A;  1R1H A;  1JK3 A;  3KME A;  4XM6 A;  1BZS A;  1ZVX A;  2D1O A;  4I03 A;  3TSK A;  5CZM A;  1GO7 P;  1S4B P;  3KWV C;  3OHO A;  2OZR A;  2OY4 A;  4DPE A;  3F16 A;  1IAE A;  3KEJ A;  3USN A;  1IAD A;  4FXY P;  4AYK A;  1O0T A;  1AF0 A;  1CIZ A;  2V4B A;  2JSD A;  3I7G A;  1JIZ A;  3LE9 A;  2OXZ A;  1SU3 A;  1WNI A;  2W15 A;  1OO9 A;  3K7L A;  1D5J A;  2RJQ A;  1FLS A;  1ROS A;  4ON1 A;  2I47 A;  1ZS0 A;  3O2X A;  3ELM A;  4EFS A;  2A8H A;  4PKV A;  1BUV M;  2MZH A;  4JQG A;  3RTT A;  2MLR A;  1USN A;  4AUO A;  1JIW P;  1IAG A;  5L79 A;  3BA0 A;  3LMC A;  1Y93 A;  966C A;  1Q3A A;  5I12 A;  1UTZ A;  2AIG P;  1G05 A;  1KUH A;  3DWB A;  1KBC A;  1KUI A;  5BPA A;  1QIA A;  3WV3 A;  1L6J A;  3KHI A;  2JNP A;  3LEA A;  3HYG A;  2W12 A;  1XUD A;  4L6T A;  1G12 A;  4GUY A;  4DV8 A;  3HBU P;  2K2G A;  1ZXV A;  4AIG A;  4CTH A;  2CKI A;  2W0D A;  1ZP5 A;  2OW1 A;  3KMC A;  3NX7 A;  3RTS A;  1QIB A;  2OXU A;  1EB6 A;  1J7N A;  2HU6 A;  4ZR5 A;  2D1N A;  2X3C A;  2ERQ A;  3F18 A;  2ERO A;  2N8R A;  3E8R A;  2DW0 A;  3TT4 A;  4G0D A;  456C A;  5LAB A;  1FM1 A;  3LK8 A;  4JA1 A;  2J83 A;  1HOV A;  1GE5 A;  3HY7 A;  5D2B A;  1BSW A;  1G4K A;  4H49 A;  4H1Q A;  1YQY A;  5I3M A;  2YIG A;  2ERP A;  2OXW A;  3F15 A;  1SAT A;  4H82 A;  1BQO A;  1K7G A;  4R3V A;  1ATL A;  1JAO A;  3F19 A;  1EAK A;  1JKY A;  1GKD A;  1GXD A;  1UEA A;  3EDZ A;  2X3A A;  2DW1 A;  4GR8 A;  4GWN A;  1O0Q A;  2YB9 A;  5B5O A;  3CKI A;  1R1J A;  3LUM A;  2Y6D A;  2TCL A;  1GE6 A;  4FVL A;  3KRY A;  5D1S A;  1CGL A;  2MLS A;  1R54 A;  3AYU A;  2WOA A;  4IN9 A;  5I2Z A;  1XFX A;  2USN A;  1Z3J A;  1A86 A;  1DMT A;  2W14 A;  1QIC A;  1UMT A;  5CUH A;  4PKR A;  4XM8 A;  4PKW A;  1IAB A;  1C8T A;  3LIK A;  3V96 B;  1MMP A;  1JJ9 A;  4IJO A;  3DL1 A;  3GBO A;  2KRJ A;  1SMP A;  1JH1 A;  1Y0V A;  3AYK A;  4JIJ A;  1HTD A;  2W13 A;  2XS3 A;  1QUA A;  1B3D A;  4FXQ A;  2OW2 A;  2MZE A;  3WV2 A;  3L0T A;  1PWQ A;  1JAP A;  3ZUK A;  1D7X A;  2XS4 A;  3EHX A;  1R1I A;  3LUN A;  5I0L A;  4GWM A;  1R55 A;  4I35 A;  5JMY A;  1YCM A;  3MA2 A;  1BQQ M;  2DDF A;  3ZVS A;  1PWV A;  1KAP P;  4GQL A;  3DPE A;  4J4M A;  3TVC A;  3F17 A;  4XBH A;  1AYK A;  3VI1 A;  2X7M A;  3AIG A;  1DTH A;  3Q2G A;  3LQ0 A;  2MZI A;  1C7K A;  1XUR A;  3LGP A;  1MMQ A;  3P24 A;  3EWJ A;  4G9L A;  4GR3 A;  3ZXH A;  2SRT A;  4XM7 A;  3HY9 A;  2FV9 A;  3B2Z A;  4L63 A;  1CQR A;  4DD8 A;  5BOT A;  5I43 A;  1ND1 A;  1CK7 A;  1JAN A;  4H3X A;  1A85 A;  5H8X A;  1KUG A;  4DF9 A;  1ZXC A;  2OW9 A;  4GF1 A;  1MMB A;  3HDB A;  3P1V A;  830C A;  1CAQ A;  1OM8 A;  1D8M A;  1C3I A;  2J0T A;  1I73 A;  3HB2 P;  4H84 A;  1EUB A;  3KEC A;  2WO8 A;  3HDA P;  3N2U A;  4JPA A;  4HMA A;  3O64 A;  5L7F A;  1OMJ A;  3DNG A;  4PKT A;  2JT5 A;  3EDG A;  1XFY A;  1G49 A;  1HFS A;  2X3B A;  5D7W A;  3G5C A;  1KUK A;  2OI0 A;  3Q2H A;  5CXA A;  1YP1 A;  2E2D A;  3HBV P;  3F1A A;  1RMZ A;  1B8Y A;  4WF6 A;  1KUF A;  2POJ A;  4A3W A;  1UMS A;  1OS2 A;  1XFU A;  4GR0 A;  1XFZ A;  2O36 A;  1CGF A;  2FV5 A;  2K9C A;  4PKU A;  1YOU A;  1SLN A;  2PJT A;  5D1U A;  3G42 A;  2WO9 A;  1FBL A;  4WKE A;  2O3E A;  2AYK A;  1BKC A;  1OS9 A;  1IAA A;  1I76 A;  1BUD A;  1Y8J A;  2DW2 A;  5BOY A;  3WV1 A;  2DDY A;  1BM6 A;  1K7I A;  3U1R A;  1SLM A;  1PWU A;  3DSL A;  1XFV A;  2L0R A;  4H30 A;  2JIH A;  4HX3 A;  1K7Q A;  3SHI A;  4ILW D;  1XUC A;  1H71 P;  1HY7 A;  3LJG A;  2OVX A;  3LKA A;  1GO8 P;  4AXQ A;  3K7N A;  1UTT A;  1CGE A;  4Q1L A;  1GKC A;  3LQB A;  4QKZ A;  3L0V A;  3LIL A;  4JP4 A;  3N2V A;  5B5P A; 
#chains in the Genus database with same CATH topology
 4PKS A;  1HV5 A;  4A7B A;  2RJP A;  3B8Z A;  2JT6 A;  3OHL A;  1JAQ A;  4WZV A;  1QJJ A;  1MMR A;  3EDI A;  3EDH A;  2CLT A;  1TVI A;  1SRP A;  5D1T A;  1ZTQ A;  3B92 A;  3TS4 A;  1MNC A;  2Z2D A;  3LJT A;  3LJZ A;  4H2E A;  1D8F A;  4PKQ A;  1BIW A;  3DPF A;  4WK7 A;  2OW0 A;  3VTG A;  3KEK A;  4WKI A;  2E3X A;  4H76 A;  1PWP A;  4IUW A;  3EHY A;  1AST A;  1OM6 A;  1BKC E;  1QJI A;  3UVC A;  1AKL A;  2Y6C A;  1XFW A;  2OY2 A;  3LIR A;  1RM8 A;  4FU4 A;  5I4O A;  2QPJ A;  3I7I A;  5D3C A;  1G9K A;  1I1I P;  1CXV A;  1BKC I;  1HFC A;  2OVZ A;  4L19 A;  1GE7 A;  1PWW A;  1OM7 A;  4XCT A;  1IAC A;  1R1H A;  1JK3 A;  3KME A;  4XM6 A;  1BZS A;  1ZVX A;  2D1O A;  4I03 A;  3TSK A;  5CZM A;  1GO7 P;  1S4B P;  3KWV C;  3OHO A;  2OZR A;  3DTE A;  2OY4 A;  4DPE A;  3F16 A;  1IAE A;  3KEJ A;  3USN A;  1IAD A;  4FXY P;  4AYK A;  1O0T A;  1AF0 A;  1CIZ A;  2V4B A;  2JSD A;  3I7G A;  1JIZ A;  3LE9 A;  2OXZ A;  1SU3 A;  1WNI A;  2W15 A;  1OO9 A;  3K7L A;  1D5J A;  2RJQ A;  1FLS A;  1ROS A;  4ON1 A;  2I47 A;  1ZS0 A;  3O2X A;  3ELM A;  4EFS A;  2A8H A;  4PKV A;  1BUV M;  2MZH A;  4JQG A;  3RTT A;  2MLR A;  1USN A;  4AUO A;  1JIW P;  1IAG A;  5L79 A;  3BA0 A;  3LMC A;  1Y93 A;  966C A;  1Q3A A;  5I12 A;  1UTZ A;  2AIG P;  1G05 A;  1KUH A;  2YUF A;  3DWB A;  1KBC A;  1KUI A;  5BPA A;  1QIA A;  3WV3 A;  1L6J A;  3KHI A;  2JNP A;  3LEA A;  3HYG A;  2W12 A;  1XUD A;  4L6T A;  1G12 A;  4GUY A;  4DV8 A;  3HBU P;  2K2G A;  1ZXV A;  4AIG A;  4CTH A;  2CKI A;  2W0D A;  1ZP5 A;  2OW1 A;  3KMC A;  3NX7 A;  3RTS A;  1QIB A;  2OXU A;  1EB6 A;  1J7N A;  2HU6 A;  4ZR5 A;  2D1N A;  2X3C A;  2ERQ A;  3F18 A;  2ERO A;  2N8R A;  3E8R A;  2DW0 A;  3TT4 A;  4G0D A;  456C A;  5LAB A;  1FM1 A;  3LK8 A;  4JA1 A;  2J83 A;  1HOV A;  1GE5 A;  3HY7 A;  5D2B A;  1BSW A;  1G4K A;  4H49 A;  4H1Q A;  1YQY A;  5I3M A;  2YIG A;  2ERP A;  2OXW A;  3F15 A;  1SAT A;  4H82 A;  1BQO A;  1K7G A;  4R3V A;  1ATL A;  1JAO A;  3F19 A;  1EAK A;  1JKY A;  1GKD A;  1GXD A;  1UEA A;  3EDZ A;  2X3A A;  2DW1 A;  4GR8 A;  4GWN A;  1O0Q A;  2YB9 A;  5B5O A;  3CKI A;  1R1J A;  3DTI A;  3LUM A;  2Y6D A;  2TCL A;  1GE6 A;  4FVL A;  3KRY A;  5D1S A;  1CGL A;  2MLS A;  1R54 A;  3DTK A;  3AYU A;  2WOA A;  4IN9 A;  5I2Z A;  1XFX A;  2USN A;  1Z3J A;  1A86 A;  1DMT A;  2W14 A;  1QIC A;  1UMT A;  5CUH A;  4PKR A;  4XM8 A;  4PKW A;  1IAB A;  1C8T A;  3LIK A;  3V96 B;  1MMP A;  1JJ9 A;  4IJO A;  3DL1 A;  3GBO A;  2KRJ A;  1SMP A;  1JH1 A;  1Y0V A;  3AYK A;  4JIJ A;  1HTD A;  2W13 A;  2XS3 A;  1QUA A;  1B3D A;  4FXQ A;  2OW2 A;  2MZE A;  3WV2 A;  3L0T A;  1PWQ A;  1JAP A;  3ZUK A;  1D7X A;  2XS4 A;  3EHX A;  1R1I A;  3LUN A;  5I0L A;  4GWM A;  1R55 A;  4I35 A;  5JMY A;  4L7A A;  1YCM A;  3MA2 A;  1BQQ M;  2DDF A;  3ZVS A;  1PWV A;  1KAP P;  4GQL A;  3DPE A;  4J4M A;  3TVC A;  3F17 A;  4XBH A;  1AYK A;  3VI1 A;  2X7M A;  3AIG A;  1DTH A;  3Q2G A;  3LQ0 A;  2MZI A;  1C7K A;  1XUR A;  3LGP A;  1MMQ A;  3P24 A;  3EWJ A;  4G9L A;  4GR3 A;  3ZXH A;  2SRT A;  4XM7 A;  3HY9 A;  2FV9 A;  3B2Z A;  4L63 A;  1CQR A;  4DD8 A;  5BOT A;  1OZ9 A;  5I43 A;  1ND1 A;  1CK7 A;  1JAN A;  4H3X A;  1A85 A;  5H8X A;  1KUG A;  4DF9 A;  1ZXC A;  2OW9 A;  4GF1 A;  1MMB A;  3HDB A;  3P1V A;  830C A;  1CAQ A;  1OM8 A;  1D8M A;  1C3I A;  2J0T A;  1I73 A;  3HB2 P;  4H84 A;  1EUB A;  3KEC A;  2WO8 A;  3HDA P;  3N2U A;  4JPA A;  4HMA A;  3O64 A;  5L7F A;  1OMJ A;  3DNG A;  4PKT A;  2JT5 A;  3EDG A;  1XFY A;  1G49 A;  1HFS A;  2X3B A;  1XAX A;  5D7W A;  3G5C A;  1KUK A;  2OI0 A;  3Q2H A;  5CXA A;  1YP1 A;  2E2D A;  3HBV P;  3F1A A;  1RMZ A;  1B8Y A;  4WF6 A;  1KUF A;  2POJ A;  4A3W A;  1UMS A;  1OS2 A;  1XFU A;  4GR0 A;  1XFZ A;  2O36 A;  1XM5 A;  1CGF A;  2FV5 A;  2K9C A;  4PKU A;  1YOU A;  1SLN A;  2PJT A;  5D1U A;  3G42 A;  2WO9 A;  1FBL A;  4WKE A;  2O3E A;  2AYK A;  1BKC A;  1OS9 A;  1IAA A;  1I76 A;  1BUD A;  1Y8J A;  2DW2 A;  5BOY A;  3WV1 A;  2DDY A;  1BM6 A;  1K7I A;  3U1R A;  1SLM A;  1PWU A;  3DSL A;  1XFV A;  2L0R A;  4H30 A;  2JIH A;  4HX3 A;  1K7Q A;  3SHI A;  4ILW D;  1XUC A;  1H71 P;  1HY7 A;  3LJG A;  2OVX A;  3LKA A;  1GO8 P;  4AXQ A;  3K7N A;  1UTT A;  1CGE A;  4Q1L A;  1GKC A;  3LQB A;  4QKZ A;  3L0V A;  3LIL A;  4JP4 A;  3N2V A;  5B5P A; 
#chains in the Genus database with same CATH homology
 4PKS A;  1HV5 A;  4A7B A;  2RJP A;  3B8Z A;  2JT6 A;  3OHL A;  1JAQ A;  4WZV A;  1QJJ A;  1MMR A;  3EDI A;  3EDH A;  2CLT A;  1SRP A;  5D1T A;  1ZTQ A;  3B92 A;  3TS4 A;  1MNC A;  2Z2D A;  3LJT A;  3LJZ A;  4H2E A;  1D8F A;  4PKQ A;  1BIW A;  3DPF A;  4WK7 A;  2OW0 A;  3VTG A;  3KEK A;  4WKI A;  2E3X A;  4H76 A;  1PWP A;  4IUW A;  3EHY A;  1AST A;  1OM6 A;  1BKC E;  1QJI A;  3UVC A;  1AKL A;  2Y6C A;  1XFW A;  2OY2 A;  3LIR A;  1RM8 A;  4FU4 A;  5I4O A;  2QPJ A;  3I7I A;  5D3C A;  1G9K A;  1I1I P;  1CXV A;  1BKC I;  1HFC A;  2OVZ A;  4L19 A;  1GE7 A;  1PWW A;  1OM7 A;  4XCT A;  1IAC A;  1R1H A;  1JK3 A;  3KME A;  4XM6 A;  1BZS A;  1ZVX A;  2D1O A;  4I03 A;  3TSK A;  5CZM A;  1GO7 P;  1S4B P;  3KWV C;  3OHO A;  2OZR A;  3DTE A;  2OY4 A;  4DPE A;  3F16 A;  1IAE A;  3KEJ A;  3USN A;  1IAD A;  4FXY P;  4AYK A;  1O0T A;  1AF0 A;  1CIZ A;  2V4B A;  2JSD A;  3I7G A;  1JIZ A;  3LE9 A;  2OXZ A;  1SU3 A;  1WNI A;  2W15 A;  1OO9 A;  3K7L A;  1D5J A;  2RJQ A;  1FLS A;  1ROS A;  4ON1 A;  2I47 A;  1ZS0 A;  3O2X A;  3ELM A;  4EFS A;  2A8H A;  4PKV A;  1BUV M;  2MZH A;  4JQG A;  3RTT A;  2MLR A;  1USN A;  4AUO A;  1JIW P;  1IAG A;  5L79 A;  3BA0 A;  3LMC A;  1Y93 A;  966C A;  1Q3A A;  5I12 A;  1UTZ A;  2AIG P;  1G05 A;  1KUH A;  2YUF A;  3DWB A;  1KBC A;  1KUI A;  5BPA A;  1QIA A;  3WV3 A;  1L6J A;  3KHI A;  2JNP A;  3LEA A;  3HYG A;  2W12 A;  1XUD A;  4L6T A;  1G12 A;  4GUY A;  4DV8 A;  3HBU P;  2K2G A;  1ZXV A;  4AIG A;  4CTH A;  2CKI A;  2W0D A;  1ZP5 A;  2OW1 A;  3KMC A;  3NX7 A;  3RTS A;  1QIB A;  2OXU A;  1EB6 A;  1J7N A;  2HU6 A;  4ZR5 A;  2D1N A;  2X3C A;  2ERQ A;  3F18 A;  2ERO A;  2N8R A;  3E8R A;  2DW0 A;  3TT4 A;  4G0D A;  456C A;  5LAB A;  1FM1 A;  3LK8 A;  4JA1 A;  2J83 A;  1HOV A;  1GE5 A;  3HY7 A;  5D2B A;  1BSW A;  1G4K A;  4H49 A;  4H1Q A;  1YQY A;  5I3M A;  2YIG A;  2ERP A;  2OXW A;  3F15 A;  1SAT A;  4H82 A;  1BQO A;  1K7G A;  4R3V A;  1ATL A;  1JAO A;  3F19 A;  1EAK A;  1JKY A;  1GKD A;  1GXD A;  1UEA A;  3EDZ A;  2X3A A;  2DW1 A;  4GR8 A;  4GWN A;  1O0Q A;  2YB9 A;  5B5O A;  3CKI A;  1R1J A;  3DTI A;  3LUM A;  2Y6D A;  2TCL A;  1GE6 A;  4FVL A;  3KRY A;  5D1S A;  1CGL A;  2MLS A;  1R54 A;  3DTK A;  3AYU A;  2WOA A;  4IN9 A;  5I2Z A;  1XFX A;  2USN A;  1Z3J A;  1A86 A;  1DMT A;  2W14 A;  1QIC A;  1UMT A;  5CUH A;  4PKR A;  4XM8 A;  4PKW A;  1IAB A;  1C8T A;  3LIK A;  3V96 B;  1MMP A;  1JJ9 A;  4IJO A;  3DL1 A;  3GBO A;  2KRJ A;  1SMP A;  1JH1 A;  1Y0V A;  3AYK A;  4JIJ A;  1HTD A;  2W13 A;  2XS3 A;  1QUA A;  1B3D A;  4FXQ A;  2OW2 A;  2MZE A;  3WV2 A;  3L0T A;  1PWQ A;  1JAP A;  3ZUK A;  1D7X A;  2XS4 A;  3EHX A;  1R1I A;  3LUN A;  5I0L A;  4GWM A;  1R55 A;  4I35 A;  5JMY A;  4L7A A;  1YCM A;  3MA2 A;  1BQQ M;  2DDF A;  3ZVS A;  1PWV A;  1KAP P;  4GQL A;  3DPE A;  4J4M A;  3TVC A;  3F17 A;  4XBH A;  1AYK A;  3VI1 A;  2X7M A;  3AIG A;  1DTH A;  3Q2G A;  3LQ0 A;  2MZI A;  1C7K A;  1XUR A;  3LGP A;  1MMQ A;  3P24 A;  3EWJ A;  4G9L A;  4GR3 A;  3ZXH A;  2SRT A;  4XM7 A;  3HY9 A;  2FV9 A;  3B2Z A;  4L63 A;  1CQR A;  4DD8 A;  5BOT A;  5I43 A;  1ND1 A;  1CK7 A;  1JAN A;  4H3X A;  1A85 A;  5H8X A;  1KUG A;  4DF9 A;  1ZXC A;  2OW9 A;  4GF1 A;  1MMB A;  3HDB A;  3P1V A;  830C A;  1CAQ A;  1OM8 A;  1D8M A;  1C3I A;  2J0T A;  1I73 A;  3HB2 P;  4H84 A;  1EUB A;  3KEC A;  2WO8 A;  3HDA P;  3N2U A;  4JPA A;  4HMA A;  3O64 A;  5L7F A;  1OMJ A;  3DNG A;  4PKT A;  2JT5 A;  3EDG A;  1XFY A;  1G49 A;  1HFS A;  2X3B A;  5D7W A;  3G5C A;  1KUK A;  2OI0 A;  3Q2H A;  5CXA A;  1YP1 A;  2E2D A;  3HBV P;  3F1A A;  1RMZ A;  1B8Y A;  4WF6 A;  1KUF A;  2POJ A;  4A3W A;  1UMS A;  1OS2 A;  1XFU A;  4GR0 A;  1XFZ A;  2O36 A;  1CGF A;  2FV5 A;  2K9C A;  4PKU A;  1YOU A;  1SLN A;  2PJT A;  5D1U A;  3G42 A;  2WO9 A;  1FBL A;  4WKE A;  2O3E A;  2AYK A;  1BKC A;  1OS9 A;  1IAA A;  1I76 A;  1BUD A;  1Y8J A;  2DW2 A;  5BOY A;  3WV1 A;  2DDY A;  1BM6 A;  1K7I A;  3U1R A;  1SLM A;  1PWU A;  3DSL A;  1XFV A;  2L0R A;  4H30 A;  2JIH A;  4HX3 A;  1K7Q A;  3SHI A;  4ILW D;  1XUC A;  1H71 P;  1HY7 A;  3LJG A;  2OVX A;  3LKA A;  1GO8 P;  4AXQ A;  3K7N A;  1UTT A;  1CGE A;  4Q1L A;  1GKC A;  3LQB A;  4QKZ A;  3L0V A;  3LIL A;  4JP4 A;  3N2V A;  5B5P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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