3WV2A

Crystal structure of the catalytic domain of mmp-13 complexed with n-(3-methoxybenzyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
169
structure length
166
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGPGDED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: Highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1 binding site
pubmed doi rcsb
molecule keywords Collagenase 3
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 44
structure length 166
sequence length 169
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2014-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3wv2A00
1Y8JA 2QPJA 5CUHA 3UVCA 1AYKA 4A7BA 4PKRA 4H49A 4EFSA 1R55A 3HY7A 3DWBA 1HTDA 4R3VA 2MZEA 1IADA 5BOYA 3HB2P 4WKIA 2O3EA 1SATA 1GE7A 4H30A 1OMJA 3DPEA 1MMBA 3LILA 2SRTA 4DV8A 3USNA 5I2ZA 3LMCA 1ASTA 3LIRA 1FLSA 1BSWA 2OW1A 5H8XA 2W12A 1PWVA 2WO8A 3KMEA 3U1RA 4L6TA 2JSDA 1XFXA 2L0RA 3EHXA 1JK3A 3LJTA 1OM7A 2D1NA 3F18A 1CK7A 5I43A 2DW2A 4L19A 3AYKA 1YP1A 3E8RA 4IUWA 1ND1A 1PWWA 2JIHA 2OXZA 3RTSA 1ZTQA 2E3XA 3LJZA 2YB9A 5I0LA 4GWMA 3KHIA 4JP4A 1XFUA 3VTGA 1ZXCA 1ZVXA 3K7NA 5D3CA 3B92A 3DL1A 2HU6A 3OHLA 2X3AA 4H3XA 3F16A 3WV3A 1BQOA 3BA0A 3K7LA 1YCMA 4AYKA 3EDGA 2YIGA 1G49A 1SLNA 3EDZA 2W15A 3VI1A 2MLRA 2USNA 3B2ZA 1JAQA 2X3CA 1R54A 3DSLA 1D7XA 1MMPA 2WOAA 4L63A 2JNPA 1CXVA 5BPAA 1ZP5A 1OO9A 5CXAA 4H2EA 1R1HA 4AIGA 1G9KA 5L79A 2OY4A 2DW1A 1I1IP 1JAPA 4DD8A 4XM6A 5I12A 2E2DA 2TCLA 456CA 4JIJA 4GR8A 3LQ0A 3TT4A 3EHYA 2OW9A 1IAGA 4H1QA 1KUHA 1PWQA 1ATLA 4H76A 4G9LA 3WV2A 1BKCE 4AXQA 3GBOA 3KEJA 3ZXHA 5D7WA 4DPEA 1I73A 1D8FA 4AUOA 2WO9A 4GF1A 1JIZA 1HY7A 3LEAA 2RJQA 1QJIA 1GE6A 5I3MA 2I47A 1DMTA 1DTHA 2ERQA 4FVLA 2CLTA 3HDAP 2RJPA 4XBHA 3N2UA 3V96B 1OS9A 1JH1A 3L0VA 1GE5A 1PWPA 1SMPA 3B8ZA 1XFWA 5D2BA 1QJJA 4HMAA 1MMRA 1JAOA 1MMQA 3AYUA 4JPAA 4IJOA 2K9CA 3KECA 1A86A 4PKQA 2ERPA 2CKIA 1CQRA 3KEKA 2Y6CA 4IN9A 2D1OA 2MZIA 1YQYA 1OM8A 3LE9A 5BOTA 2OI0A 2PJTA 4A3WA 3LIKA 1C3IA 1CGLA 4GR0A 1GO7P 3LK8A 3TSKA 1J7NA 3G5CA 3AIGA 3HY9A 1PWUA 1QICA 1BM6A 3O64A 4JA1A 2MLSA 1UMSA 3F1AA 3WV1A 3DNGA 1BQQM 1IAEA 2OVXA 2OXUA 3ELMA 1OS2A 1QUAA 1KUFA 1ZS0A 2A8HA 3I7IA 5L7FA 1HFCA 2AYKA 3L0TA 4QKZA 1RM8A 5D1TA 1CGEA 5B5PA 1IABA 1QIAA 1I76A 4JQGA 1O0QA 2V4BA 1SLMA 1JIWP 1AF0A 4ON1A 1G05A 4I03A 3Q2HA 5I4OA 3LQBA 3MA2A 4PKTA 4H84A 1FBLA 3DPFA 1BIWA 2OXWA 2JT5A 2FV5A 1XURA 1XFZA 3KRYA 1XFYA 1K7IA 3HYGA 1UTZA 3EWJA 1K7GA 1UTTA 1BUVM 3TS4A 1KUGA 4XCTA 1OM6A 1XFVA 3Q2GA 2J0TA 3ZUKA 1A85A 3EDHA 4J4MA 4G0DA 2JT6A 5D1SA 3LKAA 1QIBA 1XUCA 1HOVA 2KRJA 1EUBA 1XUDA 2W13A 4WZVA 830CA 1GO8P 4PKUA 1SRPA 1CAQA 1GXDA 5JMYA 3LUMA 1UMTA 3F19A 3RTTA 966CA 4XM8A 1KAPP 1RMZA 3LUNA 4CTHA 3F15A 1EB6A 4GWNA 1D5JA 4FU4A 4DF9A 1GKCA 1B3DA 1HV5A 2OW2A 2OW0A 2Z2DA 4WKEA 1D8MA 3CKIA 1MNCA 2K2GA 3KMCA 5B5OA 1KBCA 3HBUP 4GR3A 4FXYP 1SU3A 1JANA 1L6JA 4I35A 1ROSA 1Q3AA 4WK7A 3N2VA 2Y6DA 1Z3JA 3LJGA 1EAKA 2DW0A 4H82A 1GKDA 3OHOA 2POJA 3HDBA 1KUKA 1G4KA 1UEAA 4ILWD 2OY2A 3HBVP 4ZR5A 1R1IA 1C8TA 2DDYA 3ZVSA 1CGFA 4PKVA 2X3BA 4HX3A 1G12A 4PKSA 1ZXVA 3TVCA 2DDFA 2FV9A 2OZRA 1Y0VA 1BKCA 1WNIA 1BZSA 2W0DA 5D1UA 1BKCI 1HFSA 2W14A 1Y93A 2EROA 3NX7A 4GQLA 1FM1A 1S4BP 2OVZA 2XS4A 1H71P 2J83A 1B8YA 3O2XA 1YOUA 2XS3A 1BUDA 3F17A 3KWVC 3LGPA 4FXQA 2O36A 1CIZA 1O0TA 5LABA 3I7GA 1IAAA 1JKYA 3G42A 1C7KA 1AKLA 4WF6A 2AIGP 1R1JA 1IACA 1JJ9A 2MZHA 3P1VA 1K7QA 1KUIA 5CZMA 2N8RA 1USNA 4GUYA 3P24A 4XM7A 4PKWA 4Q1LA 2X7MA 3EDIA 3SHIA
chains in the Genus database with same CATH superfamily
1Y8JA 2QPJA 5CUHA 3UVCA 1AYKA 4A7BA 4PKRA 4H49A 4EFSA 1R55A 3HY7A 3DWBA 1HTDA 4R3VA 2MZEA 1IADA 5BOYA 3HB2P 4WKIA 2O3EA 1SATA 1GE7A 4H30A 1OMJA 3DPEA 1MMBA 3LILA 2SRTA 4DV8A 3USNA 5I2ZA 3LMCA 1ASTA 3LIRA 1FLSA 1BSWA 2OW1A 5H8XA 2W12A 1PWVA 2WO8A 2YUFA 3KMEA 3U1RA 4L6TA 2JSDA 1XFXA 2L0RA 3EHXA 1JK3A 3LJTA 1OM7A 2D1NA 3F18A 3DTIA 1CK7A 5I43A 2DW2A 4L19A 3AYKA 1YP1A 3E8RA 4IUWA 1ND1A 1PWWA 2JIHA 2OXZA 3RTSA 1ZTQA 2E3XA 3LJZA 2YB9A 5I0LA 4GWMA 3KHIA 4JP4A 1XFUA 3VTGA 1ZXCA 1ZVXA 3K7NA 5D3CA 3B92A 3DL1A 2HU6A 3OHLA 2X3AA 4H3XA 3F16A 3WV3A 1BQOA 3BA0A 3K7LA 1YCMA 4AYKA 3EDGA 2YIGA 1G49A 1SLNA 3EDZA 2W15A 3VI1A 2MLRA 2USNA 3B2ZA 1JAQA 2X3CA 1R54A 3DSLA 1D7XA 1MMPA 2WOAA 4L63A 2JNPA 1CXVA 5BPAA 1ZP5A 1OO9A 5CXAA 4H2EA 1R1HA 4AIGA 1G9KA 5L79A 2OY4A 2DW1A 1I1IP 1JAPA 4DD8A 4XM6A 5I12A 2E2DA 2TCLA 456CA 4JIJA 4GR8A 3LQ0A 3TT4A 3EHYA 2OW9A 1IAGA 3DTEA 4H1QA 1KUHA 1PWQA 1ATLA 4H76A 4G9LA 3WV2A 1BKCE 1XM5A 4AXQA 3GBOA 3KEJA 3ZXHA 5D7WA 4DPEA 3DTKA 1I73A 1D8FA 4AUOA 2WO9A 4GF1A 1JIZA 1HY7A 3LEAA 4L7AA 2RJQA 1QJIA 1GE6A 5I3MA 2I47A 1DMTA 1DTHA 2ERQA 4FVLA 2CLTA 3HDAP 2RJPA 4XBHA 3N2UA 3V96B 1OS9A 1JH1A 3L0VA 1GE5A 1PWPA 1SMPA 3B8ZA 1XFWA 5D2BA 1QJJA 4HMAA 1MMRA 1JAOA 1MMQA 3AYUA 4JPAA 4IJOA 2K9CA 3KECA 1A86A 4PKQA 2ERPA 2CKIA 1CQRA 3KEKA 2Y6CA 4IN9A 2D1OA 2MZIA 1YQYA 1OM8A 3LE9A 5BOTA 2OI0A 2PJTA 4A3WA 3LIKA 1C3IA 1CGLA 4GR0A 1GO7P 3LK8A 3TSKA 1J7NA 3G5CA 3AIGA 3HY9A 1PWUA 1QICA 1BM6A 3O64A 4JA1A 2MLSA 1UMSA 3F1AA 3WV1A 3DNGA 1BQQM 1IAEA 2OVXA 2OXUA 3ELMA 1OS2A 1QUAA 1KUFA 1ZS0A 2A8HA 3I7IA 5L7FA 1HFCA 2AYKA 3L0TA 4QKZA 1RM8A 5D1TA 1CGEA 5B5PA 1IABA 1QIAA 1I76A 4JQGA 1O0QA 2V4BA 1SLMA 1JIWP 1AF0A 4ON1A 1G05A 4I03A 3Q2HA 5I4OA 3LQBA 3MA2A 4PKTA 4H84A 1FBLA 3DPFA 1BIWA 2OXWA 2JT5A 2FV5A 1XURA 1XFZA 1XAXA 1XFYA 3KRYA 1K7IA 3HYGA 1UTZA 3EWJA 1K7GA 1UTTA 1BUVM 3TS4A 1KUGA 4XCTA 1OM6A 1XFVA 3Q2GA 2J0TA 3ZUKA 1A85A 3EDHA 4J4MA 4G0DA 2JT6A 5D1SA 3LKAA 1QIBA 1XUCA 1HOVA 2KRJA 1EUBA 1XUDA 2W13A 4WZVA 830CA 1GO8P 4PKUA 1SRPA 1CAQA 1GXDA 5JMYA 3LUMA 1UMTA 3F19A 3RTTA 966CA 4XM8A 1KAPP 1RMZA 3LUNA 4CTHA 3F15A 1EB6A 4GWNA 1D5JA 4FU4A 4DF9A 1OZ9A 1TVIA 1GKCA 1B3DA 1HV5A 2OW2A 2OW0A 2Z2DA 4WKEA 1D8MA 3CKIA 1MNCA 2K2GA 3KMCA 5B5OA 1KBCA 3HBUP 4GR3A 4FXYP 1SU3A 1JANA 1L6JA 4I35A 1ROSA 1Q3AA 4WK7A 3N2VA 2Y6DA 1Z3JA 3LJGA 1EAKA 2DW0A 4H82A 1GKDA 3OHOA 2POJA 3HDBA 1KUKA 1G4KA 1UEAA 4ILWD 2OY2A 3HBVP 4ZR5A 1R1IA 1C8TA 2DDYA 3ZVSA 1CGFA 4PKVA 2X3BA 4HX3A 1G12A 4PKSA 1ZXVA 3TVCA 2DDFA 2FV9A 2OZRA 1Y0VA 1BKCA 1WNIA 1BZSA 2W0DA 5D1UA 1BKCI 1HFSA 2W14A 1Y93A 2EROA 3NX7A 4GQLA 1FM1A 1S4BP 2OVZA 2XS4A 1H71P 2J83A 1B8YA 3O2XA 1YOUA 2XS3A 1BUDA 3F17A 3KWVC 3LGPA 4FXQA 2O36A 1CIZA 1O0TA 5LABA 3I7GA 1IAAA 1JKYA 3G42A 1C7KA 1AKLA 4WF6A 2AIGP 1R1JA 1IACA 1JJ9A 2MZHA 3P1VA 1K7QA 1KUIA 5CZMA 2N8RA 1USNA 4GUYA 3P24A 4XM7A 4PKWA 4Q1LA 2X7MA 3EDIA 3SHIA
chains in the Genus database with same CATH topology
1Y8JA 2QPJA 5CUHA 3UVCA 1AYKA 4A7BA 4PKRA 4H49A 4EFSA 1R55A 3HY7A 3DWBA 1HTDA 4R3VA 2MZEA 1IADA 5BOYA 3HB2P 4WKIA 2O3EA 1SATA 1GE7A 4H30A 1OMJA 3DPEA 1MMBA 3LILA 2SRTA 4DV8A 3USNA 5I2ZA 3LMCA 1ASTA 3LIRA 1FLSA 1BSWA 2OW1A 5H8XA 2W12A 1PWVA 2WO8A 2YUFA 3KMEA 3U1RA 4L6TA 2JSDA 1XFXA 2L0RA 3EHXA 1JK3A 3LJTA 1OM7A 2D1NA 3F18A 3DTIA 1CK7A 5I43A 2DW2A 4L19A 3AYKA 1YP1A 3E8RA 4IUWA 1ND1A 1PWWA 2JIHA 2OXZA 3RTSA 1ZTQA 2E3XA 3LJZA 2YB9A 5I0LA 4GWMA 3KHIA 4JP4A 1XFUA 3VTGA 1ZXCA 1ZVXA 3K7NA 5D3CA 3B92A 3DL1A 2HU6A 3OHLA 2X3AA 4H3XA 3F16A 3WV3A 1BQOA 3BA0A 3K7LA 1YCMA 4AYKA 3EDGA 2YIGA 1G49A 1SLNA 3EDZA 2W15A 3VI1A 2MLRA 2USNA 3B2ZA 1JAQA 2X3CA 1R54A 3DSLA 1D7XA 1MMPA 2WOAA 4L63A 2JNPA 1CXVA 5BPAA 1ZP5A 1OO9A 5CXAA 4H2EA 1R1HA 4AIGA 1G9KA 5L79A 2OY4A 2DW1A 1I1IP 1JAPA 4DD8A 4XM6A 5I12A 2E2DA 2TCLA 456CA 4JIJA 4GR8A 3LQ0A 3TT4A 3EHYA 2OW9A 1IAGA 3DTEA 4H1QA 1KUHA 1PWQA 1ATLA 4H76A 4G9LA 3WV2A 1BKCE 4AXQA 3GBOA 3KEJA 3ZXHA 5D7WA 4DPEA 3DTKA 1I73A 1D8FA 4AUOA 2WO9A 4GF1A 1JIZA 1HY7A 3LEAA 4L7AA 2RJQA 1QJIA 1GE6A 5I3MA 2I47A 1DMTA 1DTHA 2ERQA 4FVLA 2CLTA 3HDAP 2RJPA 4XBHA 3N2UA 3V96B 1OS9A 1JH1A 3L0VA 1GE5A 1PWPA 1SMPA 3B8ZA 1XFWA 5D2BA 1QJJA 4HMAA 1MMRA 1JAOA 1MMQA 3AYUA 4JPAA 4IJOA 2K9CA 3KECA 1A86A 4PKQA 2ERPA 2CKIA 1CQRA 3KEKA 2Y6CA 4IN9A 2D1OA 2MZIA 1YQYA 1OM8A 3LE9A 5BOTA 2OI0A 2PJTA 4A3WA 3LIKA 1C3IA 1CGLA 4GR0A 1GO7P 3LK8A 3TSKA 1J7NA 3G5CA 3AIGA 3HY9A 1PWUA 1QICA 1BM6A 3O64A 4JA1A 2MLSA 1UMSA 3F1AA 3WV1A 3DNGA 1BQQM 1IAEA 2OVXA 2OXUA 3ELMA 1OS2A 1QUAA 1KUFA 1ZS0A 2A8HA 3I7IA 5L7FA 1HFCA 2AYKA 3L0TA 4QKZA 1RM8A 5D1TA 1CGEA 5B5PA 1IABA 1QIAA 1I76A 4JQGA 1O0QA 2V4BA 1SLMA 1JIWP 1AF0A 4ON1A 1G05A 4I03A 3Q2HA 5I4OA 3LQBA 3MA2A 4PKTA 4H84A 1FBLA 3DPFA 1BIWA 2OXWA 2JT5A 2FV5A 1XURA 1XFZA 3KRYA 1XFYA 1K7IA 3HYGA 1UTZA 3EWJA 1K7GA 1UTTA 1BUVM 3TS4A 1KUGA 4XCTA 1OM6A 1XFVA 3Q2GA 2J0TA 3ZUKA 1A85A 3EDHA 4J4MA 4G0DA 2JT6A 5D1SA 3LKAA 1QIBA 1XUCA 1HOVA 2KRJA 1EUBA 1XUDA 2W13A 4WZVA 830CA 1GO8P 4PKUA 1SRPA 1CAQA 1GXDA 5JMYA 3LUMA 1UMTA 3F19A 3RTTA 966CA 4XM8A 1KAPP 1RMZA 3LUNA 4CTHA 3F15A 1EB6A 4GWNA 1D5JA 4FU4A 4DF9A 1GKCA 1B3DA 1HV5A 2OW2A 2OW0A 2Z2DA 4WKEA 1D8MA 3CKIA 1MNCA 2K2GA 3KMCA 5B5OA 1KBCA 3HBUP 4GR3A 4FXYP 1SU3A 1JANA 1L6JA 4I35A 1ROSA 1Q3AA 4WK7A 3N2VA 2Y6DA 1Z3JA 3LJGA 1EAKA 2DW0A 4H82A 1GKDA 3OHOA 2POJA 3HDBA 1KUKA 1G4KA 1UEAA 4ILWD 2OY2A 3HBVP 4ZR5A 1R1IA 1C8TA 2DDYA 3ZVSA 1CGFA 4PKVA 2X3BA 4HX3A 1G12A 4PKSA 1ZXVA 3TVCA 2DDFA 2FV9A 2OZRA 1Y0VA 1BKCA 1WNIA 1BZSA 2W0DA 5D1UA 1BKCI 1HFSA 2W14A 1Y93A 2EROA 3NX7A 4GQLA 1FM1A 1S4BP 2OVZA 2XS4A 1H71P 2J83A 1B8YA 3O2XA 1YOUA 2XS3A 1BUDA 3F17A 3KWVC 3LGPA 4FXQA 2O36A 1CIZA 1O0TA 5LABA 3I7GA 1IAAA 1JKYA 3G42A 1C7KA 1AKLA 4WF6A 2AIGP 1R1JA 1IACA 1JJ9A 2MZHA 3P1VA 1K7QA 1KUIA 5CZMA 2N8RA 1USNA 4GUYA 3P24A 4XM7A 4PKWA 4Q1LA 2X7MA 3EDIA 3SHIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y8J A;  2QPJ A;  5CUH A;  3UVC A;  1AYK A;  4A7B A;  4PKR A;  4H49 A;  4EFS A;  1R55 A;  3HY7 A;  3DWB A;  1HTD A;  4R3V A;  2MZE A;  1IAD A;  5BOY A;  3HB2 P;  4WKI A;  2O3E A;  1SAT A;  1GE7 A;  4H30 A;  1OMJ A;  3DPE A;  1MMB A;  3LIL A;  2SRT A;  4DV8 A;  3USN A;  5I2Z A;  3LMC A;  1AST A;  3LIR A;  1FLS A;  1BSW A;  2OW1 A;  5H8X A;  2W12 A;  1PWV A;  2WO8 A;  3KME A;  3U1R A;  4L6T A;  2JSD A;  1XFX A;  2L0R A;  3EHX A;  1JK3 A;  3LJT A;  1OM7 A;  2D1N A;  3F18 A;  1CK7 A;  5I43 A;  2DW2 A;  4L19 A;  3AYK A;  1YP1 A;  3E8R A;  4IUW A;  1ND1 A;  1PWW A;  2JIH A;  2OXZ A;  3RTS A;  1ZTQ A;  2E3X A;  3LJZ A;  2YB9 A;  5I0L A;  4GWM A;  3KHI A;  4JP4 A;  1XFU A;  3VTG A;  1ZXC A;  1ZVX A;  3K7N A;  5D3C A;  3B92 A;  3DL1 A;  2HU6 A;  3OHL A;  2X3A A;  4H3X A;  3F16 A;  3WV3 A;  1BQO A;  3BA0 A;  3K7L A;  1YCM A;  4AYK A;  3EDG A;  2YIG A;  1G49 A;  1SLN A;  3EDZ A;  2W15 A;  3VI1 A;  2MLR A;  2USN A;  3B2Z A;  1JAQ A;  2X3C A;  1R54 A;  3DSL A;  1D7X A;  1MMP A;  2WOA A;  4L63 A;  2JNP A;  1CXV A;  5BPA A;  1ZP5 A;  1OO9 A;  5CXA A;  4H2E A;  1R1H A;  4AIG A;  1G9K A;  5L79 A;  2OY4 A;  2DW1 A;  1I1I P;  1JAP A;  4DD8 A;  4XM6 A;  5I12 A;  2E2D A;  2TCL A;  456C A;  4JIJ A;  4GR8 A;  3LQ0 A;  3TT4 A;  3EHY A;  2OW9 A;  1IAG A;  4H1Q A;  1KUH A;  1PWQ A;  1ATL A;  4H76 A;  4G9L A;  3WV2 A;  1BKC E;  4AXQ A;  3GBO A;  3KEJ A;  3ZXH A;  5D7W A;  4DPE A;  1I73 A;  1D8F A;  4AUO A;  2WO9 A;  4GF1 A;  1JIZ A;  1HY7 A;  3LEA A;  2RJQ A;  1QJI A;  1GE6 A;  5I3M A;  2I47 A;  1DMT A;  1DTH A;  2ERQ A;  4FVL A;  2CLT A;  3HDA P;  2RJP A;  4XBH A;  3N2U A;  3V96 B;  1OS9 A;  1JH1 A;  3L0V A;  1GE5 A;  1PWP A;  1SMP A;  3B8Z A;  1XFW A;  5D2B A;  1QJJ A;  4HMA A;  1MMR A;  1JAO A;  1MMQ A;  3AYU A;  4JPA A;  4IJO A;  2K9C A;  3KEC A;  1A86 A;  4PKQ A;  2ERP A;  2CKI A;  1CQR A;  3KEK A;  2Y6C A;  4IN9 A;  2D1O A;  2MZI A;  1YQY A;  1OM8 A;  3LE9 A;  5BOT A;  2OI0 A;  2PJT A;  4A3W A;  3LIK A;  1C3I A;  1CGL A;  4GR0 A;  1GO7 P;  3LK8 A;  3TSK A;  1J7N A;  3G5C A;  3AIG A;  3HY9 A;  1PWU A;  1QIC A;  1BM6 A;  3O64 A;  4JA1 A;  2MLS A;  1UMS A;  3F1A A;  3WV1 A;  3DNG A;  1BQQ M;  1IAE A;  2OVX A;  2OXU A;  3ELM A;  1OS2 A;  1QUA A;  1KUF A;  1ZS0 A;  2A8H A;  3I7I A;  5L7F A;  1HFC A;  2AYK A;  3L0T A;  4QKZ A;  1RM8 A;  5D1T A;  1CGE A;  5B5P A;  1IAB A;  1QIA A;  1I76 A;  4JQG A;  1O0Q A;  2V4B A;  1SLM A;  1JIW P;  1AF0 A;  4ON1 A;  1G05 A;  4I03 A;  3Q2H A;  5I4O A;  3LQB A;  3MA2 A;  4PKT A;  4H84 A;  1FBL A;  3DPF A;  1BIW A;  2OXW A;  2JT5 A;  2FV5 A;  1XUR A;  1XFZ A;  3KRY A;  1XFY A;  1K7I A;  3HYG A;  1UTZ A;  3EWJ A;  1K7G A;  1UTT A;  1BUV M;  3TS4 A;  1KUG A;  4XCT A;  1OM6 A;  1XFV A;  3Q2G A;  2J0T A;  3ZUK A;  1A85 A;  3EDH A;  4J4M A;  4G0D A;  2JT6 A;  5D1S A;  3LKA A;  1QIB A;  1XUC A;  1HOV A;  2KRJ A;  1EUB A;  1XUD A;  2W13 A;  4WZV A;  830C A;  1GO8 P;  4PKU A;  1SRP A;  1CAQ A;  1GXD A;  5JMY A;  3LUM A;  1UMT A;  3F19 A;  3RTT A;  966C A;  4XM8 A;  1KAP P;  1RMZ A;  3LUN A;  4CTH A;  3F15 A;  1EB6 A;  4GWN A;  1D5J A;  4FU4 A;  4DF9 A;  1GKC A;  1B3D A;  1HV5 A;  2OW2 A;  2OW0 A;  2Z2D A;  4WKE A;  1D8M A;  3CKI A;  1MNC A;  2K2G A;  3KMC A;  5B5O A;  1KBC A;  3HBU P;  4GR3 A;  4FXY P;  1SU3 A;  1JAN A;  1L6J A;  4I35 A;  1ROS A;  1Q3A A;  4WK7 A;  3N2V A;  2Y6D A;  1Z3J A;  3LJG A;  1EAK A;  2DW0 A;  4H82 A;  1GKD A;  3OHO A;  2POJ A;  3HDB A;  1KUK A;  1G4K A;  1UEA A;  4ILW D;  2OY2 A;  3HBV P;  4ZR5 A;  1R1I A;  1C8T A;  2DDY A;  3ZVS A;  1CGF A;  4PKV A;  2X3B A;  4HX3 A;  1G12 A;  4PKS A;  1ZXV A;  3TVC A;  2DDF A;  2FV9 A;  2OZR A;  1Y0V A;  1BKC A;  1WNI A;  1BZS A;  2W0D A;  5D1U A;  1BKC I;  1HFS A;  2W14 A;  1Y93 A;  2ERO A;  3NX7 A;  4GQL A;  1FM1 A;  1S4B P;  2OVZ A;  2XS4 A;  1H71 P;  2J83 A;  1B8Y A;  3O2X A;  1YOU A;  2XS3 A;  1BUD A;  3F17 A;  3KWV C;  3LGP A;  4FXQ A;  2O36 A;  1CIZ A;  1O0T A;  5LAB A;  3I7G A;  1IAA A;  1JKY A;  3G42 A;  1C7K A;  1AKL A;  4WF6 A;  2AIG P;  1R1J A;  1IAC A;  1JJ9 A;  2MZH A;  3P1V A;  1K7Q A;  1KUI A;  5CZM A;  2N8R A;  1USN A;  4GUY A;  3P24 A;  4XM7 A;  4PKW A;  4Q1L A;  2X7M A;  3EDI A;  3SHI A; 
#chains in the Genus database with same CATH topology
 1Y8J A;  2QPJ A;  5CUH A;  3UVC A;  1AYK A;  4A7B A;  4PKR A;  4H49 A;  4EFS A;  1R55 A;  3HY7 A;  3DWB A;  1HTD A;  4R3V A;  2MZE A;  1IAD A;  5BOY A;  3HB2 P;  4WKI A;  2O3E A;  1SAT A;  1GE7 A;  4H30 A;  1OMJ A;  3DPE A;  1MMB A;  3LIL A;  2SRT A;  4DV8 A;  3USN A;  5I2Z A;  3LMC A;  1AST A;  3LIR A;  1FLS A;  1BSW A;  2OW1 A;  5H8X A;  2W12 A;  1PWV A;  2WO8 A;  2YUF A;  3KME A;  3U1R A;  4L6T A;  2JSD A;  1XFX A;  2L0R A;  3EHX A;  1JK3 A;  3LJT A;  1OM7 A;  2D1N A;  3F18 A;  3DTI A;  1CK7 A;  5I43 A;  2DW2 A;  4L19 A;  3AYK A;  1YP1 A;  3E8R A;  4IUW A;  1ND1 A;  1PWW A;  2JIH A;  2OXZ A;  3RTS A;  1ZTQ A;  2E3X A;  3LJZ A;  2YB9 A;  5I0L A;  4GWM A;  3KHI A;  4JP4 A;  1XFU A;  3VTG A;  1ZXC A;  1ZVX A;  3K7N A;  5D3C A;  3B92 A;  3DL1 A;  2HU6 A;  3OHL A;  2X3A A;  4H3X A;  3F16 A;  3WV3 A;  1BQO A;  3BA0 A;  3K7L A;  1YCM A;  4AYK A;  3EDG A;  2YIG A;  1G49 A;  1SLN A;  3EDZ A;  2W15 A;  3VI1 A;  2MLR A;  2USN A;  3B2Z A;  1JAQ A;  2X3C A;  1R54 A;  3DSL A;  1D7X A;  1MMP A;  2WOA A;  4L63 A;  2JNP A;  1CXV A;  5BPA A;  1ZP5 A;  1OO9 A;  5CXA A;  4H2E A;  1R1H A;  4AIG A;  1G9K A;  5L79 A;  2OY4 A;  2DW1 A;  1I1I P;  1JAP A;  4DD8 A;  4XM6 A;  5I12 A;  2E2D A;  2TCL A;  456C A;  4JIJ A;  4GR8 A;  3LQ0 A;  3TT4 A;  3EHY A;  2OW9 A;  1IAG A;  3DTE A;  4H1Q A;  1KUH A;  1PWQ A;  1ATL A;  4H76 A;  4G9L A;  3WV2 A;  1BKC E;  1XM5 A;  4AXQ A;  3GBO A;  3KEJ A;  3ZXH A;  5D7W A;  4DPE A;  3DTK A;  1I73 A;  1D8F A;  4AUO A;  2WO9 A;  4GF1 A;  1JIZ A;  1HY7 A;  3LEA A;  4L7A A;  2RJQ A;  1QJI A;  1GE6 A;  5I3M A;  2I47 A;  1DMT A;  1DTH A;  2ERQ A;  4FVL A;  2CLT A;  3HDA P;  2RJP A;  4XBH A;  3N2U A;  3V96 B;  1OS9 A;  1JH1 A;  3L0V A;  1GE5 A;  1PWP A;  1SMP A;  3B8Z A;  1XFW A;  5D2B A;  1QJJ A;  4HMA A;  1MMR A;  1JAO A;  1MMQ A;  3AYU A;  4JPA A;  4IJO A;  2K9C A;  3KEC A;  1A86 A;  4PKQ A;  2ERP A;  2CKI A;  1CQR A;  3KEK A;  2Y6C A;  4IN9 A;  2D1O A;  2MZI A;  1YQY A;  1OM8 A;  3LE9 A;  5BOT A;  2OI0 A;  2PJT A;  4A3W A;  3LIK A;  1C3I A;  1CGL A;  4GR0 A;  1GO7 P;  3LK8 A;  3TSK A;  1J7N A;  3G5C A;  3AIG A;  3HY9 A;  1PWU A;  1QIC A;  1BM6 A;  3O64 A;  4JA1 A;  2MLS A;  1UMS A;  3F1A A;  3WV1 A;  3DNG A;  1BQQ M;  1IAE A;  2OVX A;  2OXU A;  3ELM A;  1OS2 A;  1QUA A;  1KUF A;  1ZS0 A;  2A8H A;  3I7I A;  5L7F A;  1HFC A;  2AYK A;  3L0T A;  4QKZ A;  1RM8 A;  5D1T A;  1CGE A;  5B5P A;  1IAB A;  1QIA A;  1I76 A;  4JQG A;  1O0Q A;  2V4B A;  1SLM A;  1JIW P;  1AF0 A;  4ON1 A;  1G05 A;  4I03 A;  3Q2H A;  5I4O A;  3LQB A;  3MA2 A;  4PKT A;  4H84 A;  1FBL A;  3DPF A;  1BIW A;  2OXW A;  2JT5 A;  2FV5 A;  1XUR A;  1XFZ A;  1XAX A;  1XFY A;  3KRY A;  1K7I A;  3HYG A;  1UTZ A;  3EWJ A;  1K7G A;  1UTT A;  1BUV M;  3TS4 A;  1KUG A;  4XCT A;  1OM6 A;  1XFV A;  3Q2G A;  2J0T A;  3ZUK A;  1A85 A;  3EDH A;  4J4M A;  4G0D A;  2JT6 A;  5D1S A;  3LKA A;  1QIB A;  1XUC A;  1HOV A;  2KRJ A;  1EUB A;  1XUD A;  2W13 A;  4WZV A;  830C A;  1GO8 P;  4PKU A;  1SRP A;  1CAQ A;  1GXD A;  5JMY A;  3LUM A;  1UMT A;  3F19 A;  3RTT A;  966C A;  4XM8 A;  1KAP P;  1RMZ A;  3LUN A;  4CTH A;  3F15 A;  1EB6 A;  4GWN A;  1D5J A;  4FU4 A;  4DF9 A;  1OZ9 A;  1TVI A;  1GKC A;  1B3D A;  1HV5 A;  2OW2 A;  2OW0 A;  2Z2D A;  4WKE A;  1D8M A;  3CKI A;  1MNC A;  2K2G A;  3KMC A;  5B5O A;  1KBC A;  3HBU P;  4GR3 A;  4FXY P;  1SU3 A;  1JAN A;  1L6J A;  4I35 A;  1ROS A;  1Q3A A;  4WK7 A;  3N2V A;  2Y6D A;  1Z3J A;  3LJG A;  1EAK A;  2DW0 A;  4H82 A;  1GKD A;  3OHO A;  2POJ A;  3HDB A;  1KUK A;  1G4K A;  1UEA A;  4ILW D;  2OY2 A;  3HBV P;  4ZR5 A;  1R1I A;  1C8T A;  2DDY A;  3ZVS A;  1CGF A;  4PKV A;  2X3B A;  4HX3 A;  1G12 A;  4PKS A;  1ZXV A;  3TVC A;  2DDF A;  2FV9 A;  2OZR A;  1Y0V A;  1BKC A;  1WNI A;  1BZS A;  2W0D A;  5D1U A;  1BKC I;  1HFS A;  2W14 A;  1Y93 A;  2ERO A;  3NX7 A;  4GQL A;  1FM1 A;  1S4B P;  2OVZ A;  2XS4 A;  1H71 P;  2J83 A;  1B8Y A;  3O2X A;  1YOU A;  2XS3 A;  1BUD A;  3F17 A;  3KWV C;  3LGP A;  4FXQ A;  2O36 A;  1CIZ A;  1O0T A;  5LAB A;  3I7G A;  1IAA A;  1JKY A;  3G42 A;  1C7K A;  1AKL A;  4WF6 A;  2AIG P;  1R1J A;  1IAC A;  1JJ9 A;  2MZH A;  3P1V A;  1K7Q A;  1KUI A;  5CZM A;  2N8R A;  1USN A;  4GUY A;  3P24 A;  4XM7 A;  4PKW A;  4Q1L A;  2X7M A;  3EDI A;  3SHI A; 
#chains in the Genus database with same CATH homology
 1Y8J A;  2QPJ A;  5CUH A;  3UVC A;  1AYK A;  4A7B A;  4PKR A;  4H49 A;  4EFS A;  1R55 A;  3HY7 A;  3DWB A;  1HTD A;  4R3V A;  2MZE A;  1IAD A;  5BOY A;  3HB2 P;  4WKI A;  2O3E A;  1SAT A;  1GE7 A;  4H30 A;  1OMJ A;  3DPE A;  1MMB A;  3LIL A;  2SRT A;  4DV8 A;  3USN A;  5I2Z A;  3LMC A;  1AST A;  3LIR A;  1FLS A;  1BSW A;  2OW1 A;  5H8X A;  2W12 A;  1PWV A;  2WO8 A;  2YUF A;  3KME A;  3U1R A;  4L6T A;  2JSD A;  1XFX A;  2L0R A;  3EHX A;  1JK3 A;  3LJT A;  1OM7 A;  2D1N A;  3F18 A;  3DTI A;  1CK7 A;  5I43 A;  2DW2 A;  4L19 A;  3AYK A;  1YP1 A;  3E8R A;  4IUW A;  1ND1 A;  1PWW A;  2JIH A;  2OXZ A;  3RTS A;  1ZTQ A;  2E3X A;  3LJZ A;  2YB9 A;  5I0L A;  4GWM A;  3KHI A;  4JP4 A;  1XFU A;  3VTG A;  1ZXC A;  1ZVX A;  3K7N A;  5D3C A;  3B92 A;  3DL1 A;  2HU6 A;  3OHL A;  2X3A A;  4H3X A;  3F16 A;  3WV3 A;  1BQO A;  3BA0 A;  3K7L A;  1YCM A;  4AYK A;  3EDG A;  2YIG A;  1G49 A;  1SLN A;  3EDZ A;  2W15 A;  3VI1 A;  2MLR A;  2USN A;  3B2Z A;  1JAQ A;  2X3C A;  1R54 A;  3DSL A;  1D7X A;  1MMP A;  2WOA A;  4L63 A;  2JNP A;  1CXV A;  5BPA A;  1ZP5 A;  1OO9 A;  5CXA A;  4H2E A;  1R1H A;  4AIG A;  1G9K A;  5L79 A;  2OY4 A;  2DW1 A;  1I1I P;  1JAP A;  4DD8 A;  4XM6 A;  5I12 A;  2E2D A;  2TCL A;  456C A;  4JIJ A;  4GR8 A;  3LQ0 A;  3TT4 A;  3EHY A;  2OW9 A;  1IAG A;  3DTE A;  4H1Q A;  1KUH A;  1PWQ A;  1ATL A;  4H76 A;  4G9L A;  3WV2 A;  1BKC E;  4AXQ A;  3GBO A;  3KEJ A;  3ZXH A;  5D7W A;  4DPE A;  3DTK A;  1I73 A;  1D8F A;  4AUO A;  2WO9 A;  4GF1 A;  1JIZ A;  1HY7 A;  3LEA A;  4L7A A;  2RJQ A;  1QJI A;  1GE6 A;  5I3M A;  2I47 A;  1DMT A;  1DTH A;  2ERQ A;  4FVL A;  2CLT A;  3HDA P;  2RJP A;  4XBH A;  3N2U A;  3V96 B;  1OS9 A;  1JH1 A;  3L0V A;  1GE5 A;  1PWP A;  1SMP A;  3B8Z A;  1XFW A;  5D2B A;  1QJJ A;  4HMA A;  1MMR A;  1JAO A;  1MMQ A;  3AYU A;  4JPA A;  4IJO A;  2K9C A;  3KEC A;  1A86 A;  4PKQ A;  2ERP A;  2CKI A;  1CQR A;  3KEK A;  2Y6C A;  4IN9 A;  2D1O A;  2MZI A;  1YQY A;  1OM8 A;  3LE9 A;  5BOT A;  2OI0 A;  2PJT A;  4A3W A;  3LIK A;  1C3I A;  1CGL A;  4GR0 A;  1GO7 P;  3LK8 A;  3TSK A;  1J7N A;  3G5C A;  3AIG A;  3HY9 A;  1PWU A;  1QIC A;  1BM6 A;  3O64 A;  4JA1 A;  2MLS A;  1UMS A;  3F1A A;  3WV1 A;  3DNG A;  1BQQ M;  1IAE A;  2OVX A;  2OXU A;  3ELM A;  1OS2 A;  1QUA A;  1KUF A;  1ZS0 A;  2A8H A;  3I7I A;  5L7F A;  1HFC A;  2AYK A;  3L0T A;  4QKZ A;  1RM8 A;  5D1T A;  1CGE A;  5B5P A;  1IAB A;  1QIA A;  1I76 A;  4JQG A;  1O0Q A;  2V4B A;  1SLM A;  1JIW P;  1AF0 A;  4ON1 A;  1G05 A;  4I03 A;  3Q2H A;  5I4O A;  3LQB A;  3MA2 A;  4PKT A;  4H84 A;  1FBL A;  3DPF A;  1BIW A;  2OXW A;  2JT5 A;  2FV5 A;  1XUR A;  1XFZ A;  3KRY A;  1XFY A;  1K7I A;  3HYG A;  1UTZ A;  3EWJ A;  1K7G A;  1UTT A;  1BUV M;  3TS4 A;  1KUG A;  4XCT A;  1OM6 A;  1XFV A;  3Q2G A;  2J0T A;  3ZUK A;  1A85 A;  3EDH A;  4J4M A;  4G0D A;  2JT6 A;  5D1S A;  3LKA A;  1QIB A;  1XUC A;  1HOV A;  2KRJ A;  1EUB A;  1XUD A;  2W13 A;  4WZV A;  830C A;  1GO8 P;  4PKU A;  1SRP A;  1CAQ A;  1GXD A;  5JMY A;  3LUM A;  1UMT A;  3F19 A;  3RTT A;  966C A;  4XM8 A;  1KAP P;  1RMZ A;  3LUN A;  4CTH A;  3F15 A;  1EB6 A;  4GWN A;  1D5J A;  4FU4 A;  4DF9 A;  1GKC A;  1B3D A;  1HV5 A;  2OW2 A;  2OW0 A;  2Z2D A;  4WKE A;  1D8M A;  3CKI A;  1MNC A;  2K2G A;  3KMC A;  5B5O A;  1KBC A;  3HBU P;  4GR3 A;  4FXY P;  1SU3 A;  1JAN A;  1L6J A;  4I35 A;  1ROS A;  1Q3A A;  4WK7 A;  3N2V A;  2Y6D A;  1Z3J A;  3LJG A;  1EAK A;  2DW0 A;  4H82 A;  1GKD A;  3OHO A;  2POJ A;  3HDB A;  1KUK A;  1G4K A;  1UEA A;  4ILW D;  2OY2 A;  3HBV P;  4ZR5 A;  1R1I A;  1C8T A;  2DDY A;  3ZVS A;  1CGF A;  4PKV A;  2X3B A;  4HX3 A;  1G12 A;  4PKS A;  1ZXV A;  3TVC A;  2DDF A;  2FV9 A;  2OZR A;  1Y0V A;  1BKC A;  1WNI A;  1BZS A;  2W0D A;  5D1U A;  1BKC I;  1HFS A;  2W14 A;  1Y93 A;  2ERO A;  3NX7 A;  4GQL A;  1FM1 A;  1S4B P;  2OVZ A;  2XS4 A;  1H71 P;  2J83 A;  1B8Y A;  3O2X A;  1YOU A;  2XS3 A;  1BUD A;  3F17 A;  3KWV C;  3LGP A;  4FXQ A;  2O36 A;  1CIZ A;  1O0T A;  5LAB A;  3I7G A;  1IAA A;  1JKY A;  3G42 A;  1C7K A;  1AKL A;  4WF6 A;  2AIG P;  1R1J A;  1IAC A;  1JJ9 A;  2MZH A;  3P1V A;  1K7Q A;  1KUI A;  5CZM A;  2N8R A;  1USN A;  4GUY A;  3P24 A;  4XM7 A;  4PKW A;  4Q1L A;  2X7M A;  3EDI A;  3SHI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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