3X01A

Crystal structure of pip4kiibeta complex with amp
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
385
structure length
315
Chain Sequence
KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPEQYSKRFNEFMSNILT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
publication title The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
pubmed doi rcsb
source organism Homo sapiens
total genus 99
structure length 315
sequence length 385
chains with identical sequence B
ec nomenclature ec 2.7.1.149: 1-phosphatidylinositol-5-phosphate 4-kinase.
pdb deposition date 2014-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01504 PIP5K Phosphatidylinositol-4-phosphate 5-Kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.800.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol Phosphate Kinase II Beta Phosphatidylinositol Phosphate Kinase II Beta 3x01A01
3.30.810.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2 2-Layer Sandwich 3x01A02
3X01A 2YBXA 3X0CA 3X0BA 3X02A 3X03A 5E3SA 5E3UA 3X05A 3X08A 5E3TA 3X0AA 2GK9A 1BO1A 3X09A 3WZZA 3X06A 3X07A 3X04A 4TZ7A
chains in the Genus database with same CATH superfamily
3X01A 2YBXA 3X0CA 3X0BA 3X02A 3X03A 5E3SA 5E3UA 3X05A 3X08A 5E3TA 3X0AA 2GK9A 1BO1A 3X09A 3WZZA 3X06A 3X07A 3X04A 4TZ7A
chains in the Genus database with same CATH topology
3X01A 2YBXA 3X0CA 3X0BA 3X02A 3X03A 5E3SA 5E3UA 3X05A 3X08A 5E3TA 3X0AA 2GK9A 1BO1A 3X09A 3WZZA 3X06A 3X07A 3X04A 4TZ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X01 A;  2YBX A;  3X0C A;  3X0B A;  3X02 A;  3X03 A;  5E3S A;  5E3U A;  3X05 A;  3X08 A;  5E3T A;  3X0A A;  2GK9 A;  1BO1 A;  3X09 A;  3WZZ A;  3X06 A;  3X07 A;  3X04 A;  4TZ7 A; 
#chains in the Genus database with same CATH topology
 3X01 A;  2YBX A;  3X0C A;  3X0B A;  3X02 A;  3X03 A;  5E3S A;  5E3U A;  3X05 A;  3X08 A;  5E3T A;  3X0A A;  2GK9 A;  1BO1 A;  3X09 A;  3WZZ A;  3X06 A;  3X07 A;  3X04 A;  4TZ7 A; 
#chains in the Genus database with same CATH homology
 3X01 A;  2YBX A;  3X0C A;  3X0B A;  3X02 A;  3X03 A;  5E3S A;  5E3U A;  3X05 A;  3X08 A;  5E3T A;  3X0A A;  2GK9 A;  1BO1 A;  3X09 A;  3WZZ A;  3X06 A;  3X07 A;  3X04 A;  4TZ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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