3X03A

Crystal structure of pip4kiibeta complex with amppnp
Total Genus 94
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
385
structure length
320
Chain Sequence
KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTVNPEQYSKRFNEFMSNILT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase
molecule keywords Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
publication title The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
pubmed doi rcsb
source organism Homo sapiens
total genus 94
structure length 320
sequence length 385
chains with identical sequence B
ec nomenclature ec 2.7.1.149: 1-phosphatidylinositol-5-phosphate 4-kinase.
pdb deposition date 2014-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01504 PIP5K Phosphatidylinositol-4-phosphate 5-Kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.800.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol Phosphate Kinase II Beta Phosphatidylinositol Phosphate Kinase II Beta 3x03A01
3.30.810.10 Alpha Beta 2-Layer Sandwich Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2 2-Layer Sandwich 3x03A02
5E3UA 3X0AA 3X04A 1BO1A 3WZZA 3X02A 5E3TA 3X07A 2YBXA 3X0BA 2GK9A 3X08A 3X09A 4TZ7A 5E3SA 3X05A 3X06A 3X0CA 3X03A 3X01A
chains in the Genus database with same CATH superfamily
5E3UA 3X0AA 3X04A 1BO1A 3WZZA 3X02A 5E3TA 3X07A 2YBXA 3X0BA 2GK9A 3X08A 3X09A 4TZ7A 5E3SA 3X05A 3X06A 3X0CA 3X03A 3X01A
chains in the Genus database with same CATH topology
5E3UA 3X0AA 3X04A 1BO1A 3WZZA 3X02A 5E3TA 3X07A 2YBXA 3X0BA 2GK9A 3X08A 3X09A 4TZ7A 5E3SA 3X05A 3X06A 3X0CA 3X03A 3X01A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5E3U A;  3X0A A;  3X04 A;  1BO1 A;  3WZZ A;  3X02 A;  5E3T A;  3X07 A;  2YBX A;  3X0B A;  2GK9 A;  3X08 A;  3X09 A;  4TZ7 A;  5E3S A;  3X05 A;  3X06 A;  3X0C A;  3X03 A;  3X01 A; 
#chains in the Genus database with same CATH topology
 5E3U A;  3X0A A;  3X04 A;  1BO1 A;  3WZZ A;  3X02 A;  5E3T A;  3X07 A;  2YBX A;  3X0B A;  2GK9 A;  3X08 A;  3X09 A;  4TZ7 A;  5E3S A;  3X05 A;  3X06 A;  3X0C A;  3X03 A;  3X01 A; 
#chains in the Genus database with same CATH homology
 5E3U A;  3X0A A;  3X04 A;  1BO1 A;  3WZZ A;  3X02 A;  5E3T A;  3X07 A;  2YBX A;  3X0B A;  2GK9 A;  3X08 A;  3X09 A;  4TZ7 A;  5E3S A;  3X05 A;  3X06 A;  3X0C A;  3X03 A;  3X01 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...