3ZD1A

Structure of the two c-terminal domains of complement factor h related protein 2
Total Genus 19
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
124
structure length
124
Chain Sequence
GEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
pubmed doi rcsb
molecule keywords COMPLEMENT FACTOR H-RELATED PROTEIN 2
molecule tags Immune system
source organism Homo sapiens
total genus 19
structure length 124
sequence length 124
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3zd1A01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3zd1A02
1GKNA 2XWJI 1H03P 2KRIA 3L89M 2XWBF 1O9AA 1TPGA 3GOVA 4FXGG 3M7PA 1U5MA 1G4GA 2KMSA 2XRDA 3KXVA 1C1ZA 1TPNA 2RKYA 3ERBA 4LOSA 2CG6A 1UOTP 2W80A 1HCCA 2YRAA 1H2QP 1OJVA 1E88A 3CALA 1FBRA 2JRAA 4B2SA 3NFPI 1MD8A 4ZH1D 3TVJA 4WJG2 1GPZA 2CKUA 3ZD1A 2W81A 2V8EA 1VVCA 4YNXA 5JPMG 4JHSA 3EJHA 4K12A 3OEDC 2ERJA 1Q3XA 2WIIC 4AYDA 2RKZA 4A5WB 2IZ4A 2G7IA 1E8BA 1OK2A 2IZ3A 2RLPA 1PPQA 4IGDA 3R62A 1QGBA 5HYTB 2O39C 2JGWA 4AYMA 1HFHA 2LOJA 1OK3A 4F4OC 1E5GA 3KZJA 1ELVA 1OJYA 1GKGA 1SS2A 2XQWC 3OP8A 4PZ5A 4B2RA 4C16A 1G4FA 2EC3A 2CG7A 4ONTD 1QO6A 1OK9A 1H2PP 1NWVA 2UWNA 1MD7A 1H04P 2JGXA 1QUBA 2A55A 1CKLA 3ZD2A 5HYPA 3O8EB 1GHQB 1HFIA 1LY2A 1SRZA 1VVDA 2B5ID 3SW0X 2EHFA 3GXEA 3IU3I 5FO8C 1ZJKA 2XRBA 2YBYA 1TPMA 5HYUB 4KKDA 3ZRZA 4AYEA 1Z92B 5HZPB 5I0QB 1OJWA 2BZMA 4CSYA 3OXUD 3T5OA 1OK1A 4MUCA 2RLQA 4J38B 2MCYA 3MQLA 4AYIA 3RJ3D 2RL0A 4LOTA 2MCZA 4DJZA 2QY0A 3INBC 3IX0A
chains in the Genus database with same CATH superfamily
1GKNA 2XWJI 1H03P 1RLHA 2KRIA 3L89M 2XWBF 1O9AA 1TPGA 3GOVA 4FXGG 4YIZA 3M7PA 3ZLDA 1U5MA 1G4GA 2KMSA 2XRDA 3KXVA 1C1ZA 1TPNA 2RKYA 3ERBA 3FGTA 4LOSA 3VWOA 2CG6A 1UOTP 2W80A 1HCCA 2YRAA 1H2QP 1OJVA 1E88A 2X2ZA 1FBRA 2JRAA 3CALA 4B2SA 3NFPI 1MD8A 4ZH1D 3TVJA 4WJG2 1GPZA 2CKUA 3ZD1A 2W81A 2V8EA 1VVCA 3NJAA 3FGRA 4YNXA 5JPMG 4JHSA 3EJHA 4K12A 3OEDC 2ERJA 2Y8SA 1Q3XA 2WIIC 4AYDA 2RKZA 4N7EA 4A5WB 2IZ4A 2ZYCA 2G7IA 1E8BA 1OK2A 2IZ3A 2RLPA 1PPQA 3WSXA 3ZLEA 4IGDA 3R62A 1QGBA 5HYTB 2O39C 2JGWA 4AYMA 1HFHA 2LOJA 1OK3A 4F4OC 3K3TA 1E5GA 3KZJA 1ELVA 1OJYA 1GKGA 1SS2A 2XQWC 3OP8A 4PZ5A 4B2RA 4C16A 1G4FA 2EC3A 2CG7A 4ONTD 1QO6A 1OK9A 1H2PP 5DN5A 1NWVA 2UWNA 1MD7A 1H04P 2JGXA 1QUBA 2A55A 1CKLA 2I2LA 3ZD2A 3IX0A 5HYPA 3O8EB 1GHQB 1HFIA 1LY2A 1SRZA 1VVDA 2B5ID 3WSYA 3SW0X 2EHFA 3GXEA 3IU3I 5FO8C 1ZJKA 2XRBA 2YBYA 1TPMA 4BWCA 4PO7A 5DN4A 5HYUB 4KKDA 3ZRZA 4AYEA 1Z92B 5HZPB 5I0QB 1OJWA 2BZMA 2Y8RA 4CSYA 3OXUD 3T5OA 1OK1A 4MUCA 4MSLA 2RLQA 2Y8TA 4J38B 3CI0J 4APLA 2MCYA 3MQLA 4AYIA 3RJ3D 2RL0A 4LOTA 2MCZA 4DJZA 2QY0A 3INBC 3F6KA
chains in the Genus database with same CATH topology
1GKNA 2XWJI 1H03P 2KRIA 3L89M 2XWBF 1O9AA 1TPGA 3GOVA 4FXGG 3M7PA 1U5MA 1G4GA 2KMSA 2XRDA 3KXVA 1C1ZA 1TPNA 2RKYA 3ERBA 4LOSA 2CG6A 1UOTP 2W80A 1HCCA 2YRAA 1H2QP 1OJVA 1E88A 3CALA 1FBRA 2JRAA 4B2SA 3NFPI 1MD8A 4ZH1D 3TVJA 4WJG2 1GPZA 2CKUA 3ZD1A 2W81A 2V8EA 1VVCA 4YNXA 5JPMG 4JHSA 3EJHA 4K12A 3OEDC 2ERJA 1Q3XA 2WIIC 4AYDA 2RKZA 4A5WB 2IZ4A 2G7IA 1E8BA 1OK2A 2IZ3A 2RLPA 1PPQA 4IGDA 3R62A 1QGBA 5HYTB 2O39C 2JGWA 4AYMA 1HFHA 2LOJA 1OK3A 4F4OC 1E5GA 3KZJA 1ELVA 1OJYA 1GKGA 1SS2A 2XQWC 3OP8A 4PZ5A 4B2RA 4C16A 1G4FA 2EC3A 2CG7A 4ONTD 1QO6A 1OK9A 1H2PP 1NWVA 2UWNA 1MD7A 1H04P 2JGXA 1QUBA 2A55A 1CKLA 3ZD2A 5HYPA 3O8EB 1GHQB 1HFIA 1LY2A 1SRZA 1VVDA 2B5ID 3SW0X 2EHFA 3GXEA 3IU3I 5FO8C 1ZJKA 2XRBA 2YBYA 1TPMA 5HYUB 4KKDA 3ZRZA 4AYEA 1Z92B 5HZPB 5I0QB 1OJWA 2BZMA 4CSYA 3OXUD 3T5OA 1OK1A 4MUCA 2RLQA 4J38B 2MCYA 3MQLA 4AYIA 3RJ3D 2RL0A 4LOTA 2MCZA 4DJZA 2QY0A 3INBC 3IX0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GKN A;  2XWJ I;  1H03 P;  2KRI A;  3L89 M;  2XWB F;  1O9A A;  1TPG A;  3GOV A;  4FXG G;  3M7P A;  1U5M A;  1G4G A;  2KMS A;  2XRD A;  3KXV A;  1C1Z A;  1TPN A;  2RKY A;  3ERB A;  4LOS A;  2CG6 A;  1UOT P;  2W80 A;  1HCC A;  2YRA A;  1H2Q P;  1OJV A;  1E88 A;  3CAL A;  1FBR A;  2JRA A;  4B2S A;  3NFP I;  1MD8 A;  4ZH1 D;  3TVJ A;  4WJG 2;  1GPZ A;  2CKU A;  3ZD1 A;  2W81 A;  2V8E A;  1VVC A;  4YNX A;  5JPM G;  4JHS A;  3EJH A;  4K12 A;  3OED C;  2ERJ A;  1Q3X A;  2WII C;  4AYD A;  2RKZ A;  4A5W B;  2IZ4 A;  2G7I A;  1E8B A;  1OK2 A;  2IZ3 A;  2RLP A;  1PPQ A;  4IGD A;  3R62 A;  1QGB A;  5HYT B;  2O39 C;  2JGW A;  4AYM A;  1HFH A;  2LOJ A;  1OK3 A;  4F4O C;  1E5G A;  3KZJ A;  1ELV A;  1OJY A;  1GKG A;  1SS2 A;  2XQW C;  3OP8 A;  4PZ5 A;  4B2R A;  4C16 A;  1G4F A;  2EC3 A;  2CG7 A;  4ONT D;  1QO6 A;  1OK9 A;  1H2P P;  1NWV A;  2UWN A;  1MD7 A;  1H04 P;  2JGX A;  1QUB A;  2A55 A;  1CKL A;  3ZD2 A;  5HYP A;  3O8E B;  1GHQ B;  1HFI A;  1LY2 A;  1SRZ A;  1VVD A;  2B5I D;  3SW0 X;  2EHF A;  3GXE A;  3IU3 I;  5FO8 C;  1ZJK A;  2XRB A;  2YBY A;  1TPM A;  5HYU B;  4KKD A;  3ZRZ A;  4AYE A;  1Z92 B;  5HZP B;  5I0Q B;  1OJW A;  2BZM A;  4CSY A;  3OXU D;  3T5O A;  1OK1 A;  4MUC A;  2RLQ A;  4J38 B;  2MCY A;  3MQL A;  4AYI A;  3RJ3 D;  2RL0 A;  4LOT A;  2MCZ A;  4DJZ A;  2QY0 A;  3INB C;  3IX0 A; 
#chains in the Genus database with same CATH topology
 1GKN A;  2XWJ I;  1H03 P;  1RLH A;  2KRI A;  3L89 M;  2XWB F;  1O9A A;  1TPG A;  3GOV A;  4FXG G;  4YIZ A;  3M7P A;  3ZLD A;  1U5M A;  1G4G A;  2KMS A;  2XRD A;  3KXV A;  1C1Z A;  1TPN A;  2RKY A;  3ERB A;  3FGT A;  4LOS A;  3VWO A;  2CG6 A;  1UOT P;  2W80 A;  1HCC A;  2YRA A;  1H2Q P;  1OJV A;  1E88 A;  2X2Z A;  1FBR A;  2JRA A;  3CAL A;  4B2S A;  3NFP I;  1MD8 A;  4ZH1 D;  3TVJ A;  4WJG 2;  1GPZ A;  2CKU A;  3ZD1 A;  2W81 A;  2V8E A;  1VVC A;  3NJA A;  3FGR A;  4YNX A;  5JPM G;  4JHS A;  3EJH A;  4K12 A;  3OED C;  2ERJ A;  2Y8S A;  1Q3X A;  2WII C;  4AYD A;  2RKZ A;  4N7E A;  4A5W B;  2IZ4 A;  2ZYC A;  2G7I A;  1E8B A;  1OK2 A;  2IZ3 A;  2RLP A;  1PPQ A;  3WSX A;  3ZLE A;  4IGD A;  3R62 A;  1QGB A;  5HYT B;  2O39 C;  2JGW A;  4AYM A;  1HFH A;  2LOJ A;  1OK3 A;  4F4O C;  3K3T A;  1E5G A;  3KZJ A;  1ELV A;  1OJY A;  1GKG A;  1SS2 A;  2XQW C;  3OP8 A;  4PZ5 A;  4B2R A;  4C16 A;  1G4F A;  2EC3 A;  2CG7 A;  4ONT D;  1QO6 A;  1OK9 A;  1H2P P;  5DN5 A;  1NWV A;  2UWN A;  1MD7 A;  1H04 P;  2JGX A;  1QUB A;  2A55 A;  1CKL A;  2I2L A;  3ZD2 A;  3IX0 A;  5HYP A;  3O8E B;  1GHQ B;  1HFI A;  1LY2 A;  1SRZ A;  1VVD A;  2B5I D;  3WSY A;  3SW0 X;  2EHF A;  3GXE A;  3IU3 I;  5FO8 C;  1ZJK A;  2XRB A;  2YBY A;  1TPM A;  4BWC A;  4PO7 A;  5DN4 A;  5HYU B;  4KKD A;  3ZRZ A;  4AYE A;  1Z92 B;  5HZP B;  5I0Q B;  1OJW A;  2BZM A;  2Y8R A;  4CSY A;  3OXU D;  3T5O A;  1OK1 A;  4MUC A;  4MSL A;  2RLQ A;  2Y8T A;  4J38 B;  3CI0 J;  4APL A;  2MCY A;  3MQL A;  4AYI A;  3RJ3 D;  2RL0 A;  4LOT A;  2MCZ A;  4DJZ A;  2QY0 A;  3INB C;  3F6K A; 
#chains in the Genus database with same CATH homology
 1GKN A;  2XWJ I;  1H03 P;  2KRI A;  3L89 M;  2XWB F;  1O9A A;  1TPG A;  3GOV A;  4FXG G;  3M7P A;  1U5M A;  1G4G A;  2KMS A;  2XRD A;  3KXV A;  1C1Z A;  1TPN A;  2RKY A;  3ERB A;  4LOS A;  2CG6 A;  1UOT P;  2W80 A;  1HCC A;  2YRA A;  1H2Q P;  1OJV A;  1E88 A;  3CAL A;  1FBR A;  2JRA A;  4B2S A;  3NFP I;  1MD8 A;  4ZH1 D;  3TVJ A;  4WJG 2;  1GPZ A;  2CKU A;  3ZD1 A;  2W81 A;  2V8E A;  1VVC A;  4YNX A;  5JPM G;  4JHS A;  3EJH A;  4K12 A;  3OED C;  2ERJ A;  1Q3X A;  2WII C;  4AYD A;  2RKZ A;  4A5W B;  2IZ4 A;  2G7I A;  1E8B A;  1OK2 A;  2IZ3 A;  2RLP A;  1PPQ A;  4IGD A;  3R62 A;  1QGB A;  5HYT B;  2O39 C;  2JGW A;  4AYM A;  1HFH A;  2LOJ A;  1OK3 A;  4F4O C;  1E5G A;  3KZJ A;  1ELV A;  1OJY A;  1GKG A;  1SS2 A;  2XQW C;  3OP8 A;  4PZ5 A;  4B2R A;  4C16 A;  1G4F A;  2EC3 A;  2CG7 A;  4ONT D;  1QO6 A;  1OK9 A;  1H2P P;  1NWV A;  2UWN A;  1MD7 A;  1H04 P;  2JGX A;  1QUB A;  2A55 A;  1CKL A;  3ZD2 A;  5HYP A;  3O8E B;  1GHQ B;  1HFI A;  1LY2 A;  1SRZ A;  1VVD A;  2B5I D;  3SW0 X;  2EHF A;  3GXE A;  3IU3 I;  5FO8 C;  1ZJK A;  2XRB A;  2YBY A;  1TPM A;  5HYU B;  4KKD A;  3ZRZ A;  4AYE A;  1Z92 B;  5HZP B;  5I0Q B;  1OJW A;  2BZM A;  4CSY A;  3OXU D;  3T5O A;  1OK1 A;  4MUC A;  2RLQ A;  4J38 B;  2MCY A;  3MQL A;  4AYI A;  3RJ3 D;  2RL0 A;  4LOT A;  2MCZ A;  4DJZ A;  2QY0 A;  3INB C;  3IX0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...