3ZGDA

Crystal structure of a keap1 mutant
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
285
structure length
285
Chain Sequence
GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
pubmed doi rcsb
molecule keywords KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
molecule tags Transcription
source organism Homo sapiens
total genus 70
structure length 285
sequence length 285
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 3zgdA00
4XMBA 3VNGA 4IN4A 3ADEA 5FNSA 2ZWAA 4CHBA 3II7A 4N1BA 1X2JA 2VPJA 4IQKA 1ZGKA 2ZZKA 4IFJA 2XN4A 2ZW9A 5FNUA 5FNQA 4IFNX 4ZGCA 3VNHA 4CH9A 2Z32A 2FLUX 5FNRA 4IFLX 4ZY3A 2WOZA 5CGJA 5FNTA 1U6DX 1X2RA 5F72C 4L7DA 3ZGCA 2DYHA 4ASCA 4YY8A 5FZJA 3ZGDA 5FZNA 3WN7A 3WDZA 4L7BA 4L7CA
chains in the Genus database with same CATH superfamily
4HZZA 3VNGA 4K1IA 4YW1A 1B9SA 2AEPA 5FWWA 1F8CA 2VK5A 3LI5A 1E1AA 3BYCA 1EUTA 3Q6KA 4FPEA 4GZSA 1MWEA 4FJ6A 4ZY3A 4QN7A 2WOZA 3SALA 1OFZA 4HHQA 4HHOA 5FZJA 4XJUA 2QWDA 3TI3A 3SRGA 1EURA 1MZ6A 1IVGA 5JYYA 4YZ3A 3H6JA 1WCQA 4GN8A 2HU0A 4CPZA 3ADEA 5HUMA 2F24A 5HUKA 1W20A 5GX4A 1CVMA 4QN3A 4IQKA 4NC5A 2X9MA 4XJRA 2HT7A 4XJ9A 2FP8A 3LI3A 2C4AA 2ZB6A 4KS3A 5GTQA 1F8BA 4HZWA 2ISMA 2W8BA 1U6DX 1IVFA 1NMBN 4FPGA 5GX2A 1C9UA 4WA3A 3D11A 1DILA 4IN4A 4WEGA 7NN9A 4B7RA 2YA6A 2HQSA 2HTUA 4XOGA 3H71A 3TICA 1SUUA 2FP9A 4GZOA 4AGIA 4NN9A 2G8SA 1CRZA 2IARA 4B7NA 5GX1A 3I1CA 3K38A 4XJWA 4B7JA 4YY8A 4WA5A 4K1JA 4MWXA 3T1EA 2VW0A 3FVZA 3H73A 4FPJA 2DSOA 4L7BA 3V64C 1N6DA 4XMBA 1NCBN 4FPKA 2VSKA 2VPJA 4HIZA 3Q6PA 4IFNX 2QWGA 1W0PA 3B69A 4CPOA 4GZPA 2BATA 2JKBA 3SILA 2IAPA 3TI8A 5CGJA 1V0ZA 3SLIA 2XZIA 3G4EA 1MS0A 4M4UA 4GEZA 4XJZA 2BERA 1XOEA 4YZ4A 3ALWA 2AGSA 3WDZA 4C1YA 4GZTA 1V3CA 3O9JA 2YA5A 3K3AA 5HUGA 3A71A 2YDTA 3A72A 4I00A 3DR2A 5H47A 2HTRA 2FHRA 1W1XA 5GX5A 4CPMA 1Z50A 4AGTA 2W5NA 1S0JA 5FNUA 4YZ5A 4CH9A 3IAXA 2FLUX 2XCYA 1N6EA 1QLGA 2HT8A 3O9KA 4O5SA 1N1SA 1X2RA 1MS9A 1A4QA 5HX0A 2QWFA 1INXA 1B9VA 1RWIA 1IVDA 3ZGDA 2F29A 2YA7A 1MS3A 1INWA 1V0EA 2QWAA 3K36A 4H52A 1NN2A 2DG0A 1F8DA 2XZKA 4FVKA 4QN6A 1A14N 3CYEA 2QWIA 4DGRA 2W5OA 1POOA 3B7EA 4GB1A 3KYAA 3GVJA 2DG1A 2Z32A 4GN7A 2AH2A 4FPHA 3CL2A 4D52A 2SILA 1SLIA 4YW4A 5HUNA 2YA4A 2SIMA 5EX7A 4BBWA 4K3YA 2QWEA 1NMAN 2VK6A 1MS8A 4FPCA 4MWQA 1EUSA 4IMBA 1NCAN 3BEQA 2IATA 3TI5A 2ZW9A 1MR5A 4XHBA 1Z4ZA 1IVBA 2BZDA 2QWHA 2QE8A 2QWKA 1USRA 2VSMA 4Q1UA 2F28A 5FNTA 1V04A 4SLIA 3ZGCA 4KS5A 4ASCA 2IAWA 4FPYA 4FZHA 5D9CA 3U0SA 2GVXA 4D8SA 2W38A 1MZ5A 4X6KA 1NNBA 2BF6A 2W20A 2FPCA 1L7GA 1MS4A 3II7A 2VK7A 2HT5A 1X2JA 2VW1A 3TIBA 3DASA 4MWYA 5B2DA 2XN4A 3D12A 2V91A 4R40A 4MWUA 4PWZA 3TC9A 4AH4A 4Q6KA 4X4AA 2GVVA 4MWVA 3H72A 4XILA 4MX0A 3CKZA 2HTVA 4YZ2A 1INGA 3G4HA 3TIAA 1V3BA 4XMAA 4CPLA 4B7MA 4CPNA 1VCJA 4L7CA 4JMLA 3HLIA 1NSBA 4DG6A 1XOGA 4FPFA 2AEQA 3KGGA 1IJQA 2H2UA 4X49A 4N1BA 1IVCA 2ZZKA 4KS2A 1N7DA 1V0FA 4XE9A 3VNHA 2IVZA 4FPLA 5FNRA 2W8BB 1N1VA 4L7DA 2DYHA 5EO8A 3NSSA 1NCCN 3S2KA 4ZLRA 1E8TA 5M1ZA 1MS1A 3SANA 2POOA 1B9TA 4GNBA 4GJTA 4GZXA 1PJXA 2A75A 4HZXA 4D4UA 4IFJA 5FNQA 2FPBA 2YA8A 5D9DA 4YW3A 1VCUA 4XJQA 3CL0A 4HZVA 5F72C 1NPEA 1K32A 5F9TA 2IAQA 4M4NA 1KITA 4QNPA 2QWJA 1Q7FA 1ZI0A 4GNCA 3V65B 2HTWA 2P4OA 2VAQA 2F0ZA 5GX3A 4MWWA 5D9BA 3GVLA 3K39A 4GNAA 1NMCA 1NSDA 1NNAA 2F25A 4WA4A 1S18A 4UOUA 4FOQA 1E8VA 1USXA 3ALXA 4GN9A 2IAXA 5B2CA 4MZEA 1E8UA 2GVWA 3V1SA 4YW2A 4C1YB 1S0IA 4XMIA 4MJUA 3UC1A 1L7HA 2VWDA 4YW5A 2OJHA 3Q6TA 4FQ4A 3WW9A 4WEFA 1CQ1A 4ZGCA 1EUUA 4XIKA 4QN5A 1NCDN 4MJVA 1SLLA 3S94A 2F11A 4HW6A 4GZQA 1INYA 1F8EA 1NSCA 4FOWA 4UF7A 2IASA 4JF7A 4M4VA 1W8OA 3AMRA 1WCSA 3AMSA 3LI4A 4NCSA 1SO7A 1INHA 2XZJA 2HTYA 3A9HA 3INBA 3O4PA 3K37A 2VW2A 2GHSA 1W21A 1C5KA 1W8NA 1V3DA 2IAVA 2F13A 1IUCA 2IAUA 4D52B 2F27A 2IAOA 4J9TA 4QN4A 2F10A 2SLIA 3PJQA 4YZ1A 4MZAA 1H6LA 1N1YA 3A9GA 4FOYA 3S8VA 1IUBA 4A0PA 2HTQA 4MWLA 5FNSA 4KS4A 1N6FA 4CHBA 4G3NA 2CMLA 3SREA 1ZGKA 1SNTA 3GVKA 3FW0A 2QWCA 3S8ZA 1V2IA 1Z4YA 4FOVA 1L7FA 2QWBA 4IFLX 4FPOB 4X47A 1DIMA 5EO7A 4AHAA 4GZWA 4KS1A 3SOVA 4O5TA 4GDJA 3WN7A 1S1DA 2H2NA 2VVZA 3P5BL 4FP3A 4MWRA 1CRUA 2F26A 1V3EA 3E5ZA 4IYGA 1Z4WA 5NN9A 6NN9A 1Z4VA 4XJAA 2GVUA 4XIOA 4XHXA 1RWLA 2RKCA 4D52C 4HZYA 1QBIA 3OPZA 1NNCA 1N1TA 4MWJA 1MS5A 4CPYA 2C4LA 2HU4A 3NO0A 3HRPA 4K1HA 2B8HA 4FP2A 4M3MA 1W0OA 4H53A 3TI4A 4B7QA 1A4GA 1WP5A 3SOQA 2YDPA 3WWAA 2ZWAA 1IVEA 3W09A 3TI6A 1BJIA 2F12A 1Z4XA 2ZB5A 4XYXA 4K1KA 3HLHA 3SOBB 3L6VA 3NN9A 1INVA 1INFA 3JU4A 4GDIA 4MC7A 4XJ8A 5FZNA 4CSDA
chains in the Genus database with same CATH topology
4XMBA 3VNGA 4IN4A 3ADEA 5FNSA 2ZWAA 4CHBA 3II7A 4N1BA 1X2JA 2VPJA 4IQKA 1ZGKA 2ZZKA 4IFJA 2XN4A 2ZW9A 5FNUA 5FNQA 4IFNX 4ZGCA 3VNHA 4CH9A 2Z32A 2FLUX 5FNRA 4IFLX 4ZY3A 2WOZA 5CGJA 5FNTA 1U6DX 1X2RA 5F72C 4L7DA 3ZGCA 2DYHA 4ASCA 4YY8A 5FZJA 3ZGDA 5FZNA 3WN7A 3WDZA 4L7BA 4L7CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XMB A;  3VNG A;  4IN4 A;  3ADE A;  5FNS A;  2ZWA A;  4CHB A;  3II7 A;  4N1B A;  1X2J A;  2VPJ A;  4IQK A;  1ZGK A;  2ZZK A;  4IFJ A;  2XN4 A;  2ZW9 A;  5FNU A;  5FNQ A;  4IFN X;  4ZGC A;  3VNH A;  4CH9 A;  2Z32 A;  2FLU X;  5FNR A;  4IFL X;  4ZY3 A;  2WOZ A;  5CGJ A;  5FNT A;  1U6D X;  1X2R A;  5F72 C;  4L7D A;  3ZGC A;  2DYH A;  4ASC A;  4YY8 A;  5FZJ A;  3ZGD A;  5FZN A;  3WN7 A;  3WDZ A;  4L7B A;  4L7C A; 
#chains in the Genus database with same CATH topology
 4HZZ A;  3VNG A;  4K1I A;  4YW1 A;  1B9S A;  2AEP A;  5FWW A;  1F8C A;  2VK5 A;  3LI5 A;  1E1A A;  3BYC A;  1EUT A;  3Q6K A;  4FPE A;  4GZS A;  1MWE A;  4FJ6 A;  4ZY3 A;  4QN7 A;  2WOZ A;  3SAL A;  1OFZ A;  4HHQ A;  4HHO A;  5FZJ A;  4XJU A;  2QWD A;  3TI3 A;  3SRG A;  1EUR A;  1MZ6 A;  1IVG A;  5JYY A;  4YZ3 A;  3H6J A;  1WCQ A;  4GN8 A;  2HU0 A;  4CPZ A;  3ADE A;  5HUM A;  2F24 A;  5HUK A;  1W20 A;  5GX4 A;  1CVM A;  4QN3 A;  4IQK A;  4NC5 A;  2X9M A;  4XJR A;  2HT7 A;  4XJ9 A;  2FP8 A;  3LI3 A;  2C4A A;  2ZB6 A;  4KS3 A;  5GTQ A;  1F8B A;  4HZW A;  2ISM A;  2W8B A;  1U6D X;  1IVF A;  1NMB N;  4FPG A;  5GX2 A;  1C9U A;  4WA3 A;  3D11 A;  1DIL A;  4IN4 A;  4WEG A;  7NN9 A;  4B7R A;  2YA6 A;  2HQS A;  2HTU A;  4XOG A;  3H71 A;  3TIC A;  1SUU A;  2FP9 A;  4GZO A;  4AGI A;  4NN9 A;  2G8S A;  1CRZ A;  2IAR A;  4B7N A;  5GX1 A;  3I1C A;  3K38 A;  4XJW A;  4B7J A;  4YY8 A;  4WA5 A;  4K1J A;  4MWX A;  3T1E A;  2VW0 A;  3FVZ A;  3H73 A;  4FPJ A;  2DSO A;  4L7B A;  3V64 C;  1N6D A;  4XMB A;  1NCB N;  4FPK A;  2VSK A;  2VPJ A;  4HIZ A;  3Q6P A;  4IFN X;  2QWG A;  1W0P A;  3B69 A;  4CPO A;  4GZP A;  2BAT A;  2JKB A;  3SIL A;  2IAP A;  3TI8 A;  5CGJ A;  1V0Z A;  3SLI A;  2XZI A;  3G4E A;  1MS0 A;  4M4U A;  4GEZ A;  4XJZ A;  2BER A;  1XOE A;  4YZ4 A;  3ALW A;  2AGS A;  3WDZ A;  4C1Y A;  4GZT A;  1V3C A;  3O9J A;  2YA5 A;  3K3A A;  5HUG A;  3A71 A;  2YDT A;  3A72 A;  4I00 A;  3DR2 A;  5H47 A;  2HTR A;  2FHR A;  1W1X A;  5GX5 A;  4CPM A;  1Z50 A;  4AGT A;  2W5N A;  1S0J A;  5FNU A;  4YZ5 A;  4CH9 A;  3IAX A;  2FLU X;  2XCY A;  1N6E A;  1QLG A;  2HT8 A;  3O9K A;  4O5S A;  1N1S A;  1X2R A;  1MS9 A;  1A4Q A;  5HX0 A;  2QWF A;  1INX A;  1B9V A;  1RWI A;  1IVD A;  3ZGD A;  2F29 A;  2YA7 A;  1MS3 A;  1INW A;  1V0E A;  2QWA A;  3K36 A;  4H52 A;  1NN2 A;  2DG0 A;  1F8D A;  2XZK A;  4FVK A;  4QN6 A;  1A14 N;  3CYE A;  2QWI A;  4DGR A;  2W5O A;  1POO A;  3B7E A;  4GB1 A;  3KYA A;  3GVJ A;  2DG1 A;  2Z32 A;  4GN7 A;  2AH2 A;  4FPH A;  3CL2 A;  4D52 A;  2SIL A;  1SLI A;  4YW4 A;  5HUN A;  2YA4 A;  2SIM A;  5EX7 A;  4BBW A;  4K3Y A;  2QWE A;  1NMA N;  2VK6 A;  1MS8 A;  4FPC A;  4MWQ A;  1EUS A;  4IMB A;  1NCA N;  3BEQ A;  2IAT A;  3TI5 A;  2ZW9 A;  1MR5 A;  4XHB A;  1Z4Z A;  1IVB A;  2BZD A;  2QWH A;  2QE8 A;  2QWK A;  1USR A;  2VSM A;  4Q1U A;  2F28 A;  5FNT A;  1V04 A;  4SLI A;  3ZGC A;  4KS5 A;  4ASC A;  2IAW A;  4FPY A;  4FZH A;  5D9C A;  3U0S A;  2GVX A;  4D8S A;  2W38 A;  1MZ5 A;  4X6K A;  1NNB A;  2BF6 A;  2W20 A;  2FPC A;  1L7G A;  1MS4 A;  3II7 A;  2VK7 A;  2HT5 A;  1X2J A;  2VW1 A;  3TIB A;  3DAS A;  4MWY A;  5B2D A;  2XN4 A;  3D12 A;  2V91 A;  4R40 A;  4MWU A;  4PWZ A;  3TC9 A;  4AH4 A;  4Q6K A;  4X4A A;  2GVV A;  4MWV A;  3H72 A;  4XIL A;  4MX0 A;  3CKZ A;  2HTV A;  4YZ2 A;  1ING A;  3G4H A;  3TIA A;  1V3B A;  4XMA A;  4CPL A;  4B7M A;  4CPN A;  1VCJ A;  4L7C A;  4JML A;  3HLI A;  1NSB A;  4DG6 A;  1XOG A;  4FPF A;  2AEQ A;  3KGG A;  1IJQ A;  2H2U A;  4X49 A;  4N1B A;  1IVC A;  2ZZK A;  4KS2 A;  1N7D A;  1V0F A;  4XE9 A;  3VNH A;  2IVZ A;  4FPL A;  5FNR A;  2W8B B;  1N1V A;  4L7D A;  2DYH A;  5EO8 A;  3NSS A;  1NCC N;  3S2K A;  4ZLR A;  1E8T A;  5M1Z A;  1MS1 A;  3SAN A;  2POO A;  1B9T A;  4GNB A;  4GJT A;  4GZX A;  1PJX A;  2A75 A;  4HZX A;  4D4U A;  4IFJ A;  5FNQ A;  2FPB A;  2YA8 A;  5D9D A;  4YW3 A;  1VCU A;  4XJQ A;  3CL0 A;  4HZV A;  5F72 C;  1NPE A;  1K32 A;  5F9T A;  2IAQ A;  4M4N A;  1KIT A;  4QNP A;  2QWJ A;  1Q7F A;  1ZI0 A;  4GNC A;  3V65 B;  2HTW A;  2P4O A;  2VAQ A;  2F0Z A;  5GX3 A;  4MWW A;  5D9B A;  3GVL A;  3K39 A;  4GNA A;  1NMC A;  1NSD A;  1NNA A;  2F25 A;  4WA4 A;  1S18 A;  4UOU A;  4FOQ A;  1E8V A;  1USX A;  3ALX A;  4GN9 A;  2IAX A;  5B2C A;  4MZE A;  1E8U A;  2GVW A;  3V1S A;  4YW2 A;  4C1Y B;  1S0I A;  4XMI A;  4MJU A;  3UC1 A;  1L7H A;  2VWD A;  4YW5 A;  2OJH A;  3Q6T A;  4FQ4 A;  3WW9 A;  4WEF A;  1CQ1 A;  4ZGC A;  1EUU A;  4XIK A;  4QN5 A;  1NCD N;  4MJV A;  1SLL A;  3S94 A;  2F11 A;  4HW6 A;  4GZQ A;  1INY A;  1F8E A;  1NSC A;  4FOW A;  4UF7 A;  2IAS A;  4JF7 A;  4M4V A;  1W8O A;  3AMR A;  1WCS A;  3AMS A;  3LI4 A;  4NCS A;  1SO7 A;  1INH A;  2XZJ A;  2HTY A;  3A9H A;  3INB A;  3O4P A;  3K37 A;  2VW2 A;  2GHS A;  1W21 A;  1C5K A;  1W8N A;  1V3D A;  2IAV A;  2F13 A;  1IUC A;  2IAU A;  4D52 B;  2F27 A;  2IAO A;  4J9T A;  4QN4 A;  2F10 A;  2SLI A;  3PJQ A;  4YZ1 A;  4MZA A;  1H6L A;  1N1Y A;  3A9G A;  4FOY A;  3S8V A;  1IUB A;  4A0P A;  2HTQ A;  4MWL A;  5FNS A;  4KS4 A;  1N6F A;  4CHB A;  4G3N A;  2CML A;  3SRE A;  1ZGK A;  1SNT A;  3GVK A;  3FW0 A;  2QWC A;  3S8Z A;  1V2I A;  1Z4Y A;  4FOV A;  1L7F A;  2QWB A;  4IFL X;  4FPO B;  4X47 A;  1DIM A;  5EO7 A;  4AHA A;  4GZW A;  4KS1 A;  3SOV A;  4O5T A;  4GDJ A;  3WN7 A;  1S1D A;  2H2N A;  2VVZ A;  3P5B L;  4FP3 A;  4MWR A;  1CRU A;  2F26 A;  1V3E A;  3E5Z A;  4IYG A;  1Z4W A;  5NN9 A;  6NN9 A;  1Z4V A;  4XJA A;  2GVU A;  4XIO A;  4XHX A;  1RWL A;  2RKC A;  4D52 C;  4HZY A;  1QBI A;  3OPZ A;  1NNC A;  1N1T A;  4MWJ A;  1MS5 A;  4CPY A;  2C4L A;  2HU4 A;  3NO0 A;  3HRP A;  4K1H A;  2B8H A;  4FP2 A;  4M3M A;  1W0O A;  4H53 A;  3TI4 A;  4B7Q A;  1A4G A;  1WP5 A;  3SOQ A;  2YDP A;  3WWA A;  2ZWA A;  1IVE A;  3W09 A;  3TI6 A;  1BJI A;  2F12 A;  1Z4X A;  2ZB5 A;  4XYX A;  4K1K A;  3HLH A;  3SOB B;  3L6V A;  3NN9 A;  1INV A;  1INF A;  3JU4 A;  4GDI A;  4MC7 A;  4XJ8 A;  5FZN A;  4CSD A; 
#chains in the Genus database with same CATH homology
 4XMB A;  3VNG A;  4IN4 A;  3ADE A;  5FNS A;  2ZWA A;  4CHB A;  3II7 A;  4N1B A;  1X2J A;  2VPJ A;  4IQK A;  1ZGK A;  2ZZK A;  4IFJ A;  2XN4 A;  2ZW9 A;  5FNU A;  5FNQ A;  4IFN X;  4ZGC A;  3VNH A;  4CH9 A;  2Z32 A;  2FLU X;  5FNR A;  4IFL X;  4ZY3 A;  2WOZ A;  5CGJ A;  5FNT A;  1U6D X;  1X2R A;  5F72 C;  4L7D A;  3ZGC A;  2DYH A;  4ASC A;  4YY8 A;  5FZJ A;  3ZGD A;  5FZN A;  3WN7 A;  3WDZ A;  4L7B A;  4L7C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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