3ZM1A

Catalytic domain of human shp2
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
282
structure length
259
Chain Sequence
GAHMWEEFETLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Selective Inhibitors of the Protein Tyrosine Phosphatase Shp2 Block Cellular Motility and Growth of Cancer Cells in Vitro and in Vivo.
pubmed doi rcsb
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11
molecule tags Hydrolase
source organism Homo sapiens
total genus 91
structure length 259
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2013-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3zm1A00
1RPMA 3S3KA 2CMCA 2FJMA 2CNGA 2PT0A 3ZMPA 2PA5A 3A5JA 3RO1A 3RGOA 4Z6BA 2NZ6A 2F6WA 4H1OA 1PTVA 3BM8A 1V3AA 5K9WA 2VEUA 1YGRA 1PTYA 3BLTA 4KYRA 3O4TA 1EEOA 5BZZA 4D3RA 4QAPA 2CNHA 1YZ4A 1Q6NA 2AZRA 4QUMA 2C7SA 2YDUA 2VEVA 1WAXA 3V0EA 3QCNA 1NNYA 5K25A 3QCKA 4WTYA 4OHHA 1GFYA 2CM3A 1XM2A 5IBMA 2Y2FA 1D5RA 1T49A 2GJTA 4RKKA 4BPCA 2B4OA 4RDDA 1OEUA 3QCCA 3QCMA 3H2XA 1C86A 1G1HA 4D3PA 2HCMA 2R0BA 3D9CA 4AZ1A 4NYHA 1U26A 1G7FA 3ZM1A 4HJQA 4D3QA 4OHDA 1KAKA 1Q6SA 5KA0A 3QCDA 1NL9A 3QCEA 5KABA 1G4US 3ZM0A 1QXKA 4JBCA 5IBSA 3RGQA 4WOHA 3O3LA 1EENA 1I9TA 2ZN7A 3F99A 2I4GA 1G1FA 3D1HA 2B4PA 1LARA 4KYQA 4OHLA 3QCFA 4B04A 1T48A 2J16B 2F6VA 1A5YA 3D42A 1OHCA 2P4DA 3D1QA 4NWGA 1SUGA 2Y96A 3OMHA 3GXHA 4R30A 2F6ZA 4KI9A 4DGPA 2A8BA 3QCIA 2HNQA 2B07A 4GE6A 4S0GA 1ECVA 1Q1MA 3OLRA 2I75A 4HJPA 3CM3A 1FPRA 2H04A 1LYVA 1JLNA 4GFUA 1PTUA 4JMKA 3ZV2A 1OEMX 5MMZB 1T4JA 3QKPA 1YTWA 2I6PA 1NZ7A 4RH9A 4ERCA 5KA8A 2F70A 2PI7A 5KA4A 3B7OA 3MOZA 4GRZA 1ZC0A 2JJDA 3F41A 2HY3A 3O4SA 1QZ0A 4MBBA 2VEYA 2E0TA 5HDEA 1C87A 2VEWA 1WCHA 1YFOA 2I3UA 3N0AA 2CNEA 1X24A 1YN9A 3BLUA 3S3HA 1ZZWA 2BIJA 3EZZA 4GS0A 1XXPA 2PSZA 5I6VA 1XXVA 2NT2A 2H4VA 2DXPA 1OHDA 4QBWA 2H4KA 1G4WR 3F81A 4OHIA 2G59A 2I5XA 1OETA 5KAAA 2BZLA 1BZHA 1PTTA 1Q6PA 3AWFA 4QBEA 4ZN5A 5KA3A 3V0IA 3GXGA 4TVVA 1PA9A 3V0FA 3ZM2A 1PYNA 1PH0A 2GP0A 3V0HA 1G7GA 2Q05A 5KA2A 1J4XA 2I6MA 3M4UA 1PA1A 2CM7A 2VEXA 2ZMMA 2Q47A 3S4OA 4H34A 1YPTA 2NT7A 4Y14A 2PQ5A 2I6IA 4NWFA 2GWOA 1JF7A 1L8GA 4HRFA 4YR8B 5KA7A 5K23A 2CMBA 2B3OA 1ZCLA 4J51A 1YGUA 2CFVA 1G1GA 1BZCA 4WU3A 2OZ5A 3D44A 2QBSA 1OHEA 1YWFA 1VHRA 2F6TA 4ICZA 3D1OA 3O5XA 2P6XA 2BGDA 1OESA 1OEVA 1ONZA 1RXDA 2BV5A 2I4EA 3QCJA 3EU0A 4PVGA 2I3RA 1U25A 3F9BA 2RF6A 3BRHA 2H02A 2QBRA 1OEOX 3QCGA 3I80A 1LQFA 5BX1A 3SMEA 1FPZA 5M43A 4PYHA 5K24A 2C46A 2CM8A 3AWGA 4IKCA 2I6OA 2QBPA 2I4HA 1C83A 2A3KA 4JMJA 2HNPA 3QCHA 1GWZA 3MOWA 4R0TA 3V0DA 4R0SA 1ONYA 2OUDA 4RH5A 1MKPA 4ZI4A 1L8KA 2F71A 3S3FA 4GWFA 2NLKA 2WGPA 2B49A 4WU2A 2J16A 1WRMA 5BUGA 5KA1A 2FJNA 3EMUA 4GRYA 1YTSA 2HXPA 1I57A 3I36A 2F6FA 2HB1A 2B4UA 1Q6JA 4RHGA 1U24A 3MMJA 1KAVA 4ZRTA 1C84A 2QCTA 1YTNA 3I7ZA 2F46A 3S4EA 3QCLA 2CNFA 2NV5A 3AWEA 2SHPA 2H4GA 1XRIA 3PS5A 5LXQB 2HVLA 3EB1A 3RZ2A 4JNBA 3SR9A 2MBCA 2OC3A 2HC1A 1FQ1A 1R6HA 3CWEA 3V0JA 1C85A 4QUNA 4GE2A 2QBQA 5J8RA 3LJ8A 2FH7A 1Q6MA 2CM2A 2I1YA 5BZXA 5EHRA 4OHEA 5GTJA 1I9SA 3S3EA 1BZJA 2I6JA 2NTAA 4GFVA 4Y2EA 2ESBA 2H03A 5K22A 1P15A 2G6ZA 2F6YA 3U96A 1C88A 2J17A 2QEPA 1PXHA 1NO6A 5EHPA 1NWLA 3V0GA 1NWEA 4YAAA 2QDCA 3QKQA 3F9AA 2QDPA 3ZM3A 2CMAA 2BGEA 1XBOA 5AWXA 4RI4A 3ZMQA 3QCBA 2CNIA 1AAXA 2CJZA 3O4UA 3NMEA 4BJOA 2PBNA 2I42A 2OOQA 2QCJA 2IMGA 1ZCKA 4GE5A 1M3GA 2AHSA 5KADA 1Q6TA 2B4SA 2M3VA 5KACA 5K9VA 4DGXA 4QAHA 3EAXA 4NNDA 2HC2A 4NX8A 5KA9A 2QDMA 4RI5A 4I8NA 3A5KA
chains in the Genus database with same CATH superfamily
1RPMA 3S3KA 2CMCA 2FJMA 3ZM5A 2CNGA 2PT0A 3ZMPA 2PA5A 3A5JA 3RO1A 3RGOA 4Z6BA 2NZ6A 2Y67A 2F6WA 4H1OA 1PTVA 3BM8A 1V3AA 5K9WA 2VEUA 1YGRA 1PTYA 3BLTA 3PYZA 4KYRA 3O4TA 1EEOA 5BZZA 4D3RA 4QAPA 3QCZA 1EEHA 2CNHA 1YZ4A 1Q6NA 2AZRA 4QUMA 2C7SA 2YDUA 2VEVA 2AM2A 1WAXA 3V0EA 3QCNA 1NNYA 5K25A 3QCKA 4WTYA 4OHHA 1GFYA 2CM3A 1XM2A 5IBMA 2Y2FA 1D5RA 1T49A 2GJTA 4RKKA 4BPCA 4C12A 1W78A 2B4OA 1E0DA 4RDDA 1OEUA 3QCCA 3QCMA 3H2XA 1C86A 1G1HA 2Y1OA 4D3PA 2HCMA 2R0BA 2WJPA 3D9CA 4AZ1A 4NYHA 1U26A 1G7FA 3ZM1A 4HJQA 4D3QA 4OHDA 1KAKA 1Q6SA 5KA0A 3QCDA 1W7KA 1NL9A 3QCEA 5KABA 1G4US 3ZM0A 1QXKA 4JBCA 5IBSA 3RGQA 4WOHA 3O3LA 1EENA 1I9TA 2ZN7A 3F99A 2I4GA 1G1FA 3D1HA 2B4PA 1LARA 4KYQA 4OHLA 3QCFA 4B04A 4C13A 2VTEA 1T48A 3N2AA 2J16B 2F6VA 1A5YA 3D42A 1OHCA 2P4DA 3D1QA 4NWGA 1SUGA 2Y96A 3OMHA 3GXHA 1GQYA 4R30A 2F6ZA 4KI9A 4DGPA 2A8BA 3QCIA 2HNQA 1J6UA 2B07A 4GE6A 4S0GA 1ECVA 1Q1MA 3OLRA 2I75A 3ZM6A 3NRSA 2XJAA 4HJPA 3CM3A 1FPRA 2H04A 1LYVA 1JLNA 4GFUA 1PTUA 1UAGA 2WTZA 1OEMX 4JMKA 3ZV2A 1JBWA 5MMZB 1T4JA 3QKPA 1YTWA 2UUPA 2I6PA 4BUCA 1NZ7A 4RH9A 4ERCA 5KA8A 2F70A 2PI7A 5KA4A 1GG4A 3B7OA 3MOZA 4GRZA 1ZC0A 2JJDA 3F41A 2HY3A 3O4SA 1QZ0A 4MBBA 2VEYA 2E0TA 5HDEA 1C87A 2VEWA 1WCHA 1YFOA 2I3UA 3N0AA 2CNEA 1X24A 1YN9A 3BLUA 4QDIA 1ZZWA 3S3HA 2BIJA 3EZZA 4GS0A 1XXPA 3MVNA 2PSZA 5I6VA 1XXVA 2NT2A 2H4VA 2DXPA 1OHDA 4QBWA 2H4KA 1G4WR 3F81A 4BUBA 4OHIA 2G59A 2I5XA 1OETA 5KAAA 2BZLA 1BZHA 1PTTA 1Q6PA 3AWFA 4QBEA 4ZN5A 5KA3A 3V0IA 3GXGA 4TVVA 1PA9A 1JBVA 3V0FA 3ZM2A 1PYNA 1PH0A 2GP0A 3V0HA 1G7GA 2Q05A 5KA2A 1J4XA 2I6MA 3M4UA 1PA1A 1GQQA 2CM7A 2VEXA 2ZMMA 2Q47A 3S4OA 4H34A 1YPTA 2NT7A 3LK7A 4Y14A 2VTDA 2PQ5A 2I6IA 4NWFA 2GWOA 1JF7A 1L8GA 4HV4A 4HRFA 4YR8B 5KA7A 5K23A 2CMBA 4CVMA 2B3OA 1ZCLA 4J51A 1YGUA 2CFVA 1G1GA 1BZCA 3ZL8A 4UAGA 4WU3A 1O5ZA 2VORA 2OZ5A 2XPCA 3D44A 2QBSA 1OHEA 2UUOA 1YWFA 1VHRA 2UAGA 2F6TA 4ICZA 1E8CA 3D1OA 3O5XA 2AM1A 2P6XA 2BGDA 1OESA 1OEVA 1ONZA 1RXDA 2BV5A 2I4EA 3QCJA 3EU0A 2Y66A 4PVGA 2I3RA 1U25A 3F9BA 2RF6A 3BRHA 2H02A 2QBRA 1OEOX 3QCGA 3I80A 1LQFA 5BX1A 3SMEA 1FPZA 5M43A 4PYHA 5K24A 2JFGA 2C46A 2CM8A 3AWGA 2VOSA 4IKCA 4QF5A 2I6OA 2QBPA 2I4HA 1C83A 2A3KA 4JMJA 2HNPA 3QCHA 1GWZA 3MOWA 4R0TA 3V0DA 4R0SA 1ONYA 2OUDA 4RH5A 1MKPA 4ZI4A 1L8KA 2F71A 3S3FA 4GWFA 2NLKA 2WGPA 2B49A 4WU2A 2J16A 1WRMA 5BUGA 5KA1A 1P31A 2FJNA 3EMUA 4GRYA 2Y68A 1YTSA 2HXPA 1I57A 3I36A 2F6FA 2HB1A 2B4UA 2X5OA 1Q6JA 4RHGA 1U24A 3MMJA 1KAVA 4ZRTA 1C84A 2QCTA 1YTNA 3I7ZA 2F46A 3S4EA 3QCLA 2CNFA 2NV5A 3AWEA 2SHPA 2H4GA 1XRIA 3PS5A 5LXQB 2HVLA 3EB1A 3RZ2A 4JNBA 3SR9A 2MBCA 2OC3A 2HC1A 1FQ1A 1R6HA 3CWEA 3V0JA 1C85A 4QUNA 4GE2A 2QBQA 5J8RA 3LJ8A 2FH7A 1Q6MA 2CM2A 2I1YA 5BZXA 5EHRA 4OHEA 5GTJA 1I9SA 3HN7A 3S3EA 1BZJA 2I6JA 2NTAA 4GFVA 4Y2EA 5A5FA 2ESBA 2H03A 5K22A 1P15A 2G6ZA 2F6YA 2JFFA 3U96A 1P3DA 1C88A 2J17A 4CVKA 2QEPA 2GC5A 1PXHA 1NO6A 5EHPA 1NWLA 1FGSA 3V0GA 1NWEA 4YAAA 2QDCA 3QKQA 3F9AA 2GC6A 2QDPA 3ZM3A 2CMAA 2BGEA 1XBOA 5AWXA 4RI4A 3ZMQA 3QCBA 2CNIA 1AAXA 2CJZA 3O4UA 3NMEA 4BJOA 2PBNA 2GCBA 5A5EA 2I42A 2OOQA 2QCJA 2IMGA 4ZIYA 1ZCKA 4GE5A 1M3GA 2AHSA 5KADA 1Q6TA 2B4SA 2M3VA 5KACA 4CVLA 5K9VA 4DGXA 2JFHA 4QAHA 3EAXA 4NNDA 2HC2A 2GCAA 4NX8A 3UAGA 5KA9A 2QDMA 4RI5A 4I8NA 3A5KA 2F00A
chains in the Genus database with same CATH topology
1RPMA 3S3KA 2CMCA 2FJMA 2CNGA 2PT0A 3ZMPA 2PA5A 3A5JA 3RO1A 3RGOA 4Z6BA 2NZ6A 2F6WA 4H1OA 1PTVA 3BM8A 1V3AA 5K9WA 2VEUA 1YGRA 1PTYA 3BLTA 4KYRA 3O4TA 1EEOA 5BZZA 4D3RA 4QAPA 2CNHA 1YZ4A 1Q6NA 2AZRA 4QUMA 2C7SA 2YDUA 2VEVA 1WAXA 3V0EA 3QCNA 1NNYA 5K25A 3QCKA 4WTYA 4OHHA 1GFYA 2CM3A 1XM2A 5IBMA 2Y2FA 1D5RA 1T49A 2GJTA 4RKKA 4BPCA 2B4OA 4RDDA 1OEUA 3QCCA 3QCMA 3H2XA 1C86A 1G1HA 4D3PA 2HCMA 2R0BA 3D9CA 4AZ1A 4NYHA 1U26A 1G7FA 3ZM1A 4HJQA 4D3QA 4OHDA 1KAKA 1Q6SA 5KA0A 3QCDA 1NL9A 3QCEA 5KABA 1G4US 3ZM0A 1QXKA 4JBCA 5IBSA 3RGQA 4WOHA 3O3LA 1EENA 1I9TA 2ZN7A 3F99A 2I4GA 1G1FA 3D1HA 2B4PA 1LARA 4KYQA 4OHLA 3QCFA 4B04A 1T48A 2J16B 2F6VA 1A5YA 3D42A 1OHCA 2P4DA 3D1QA 4NWGA 1SUGA 2Y96A 3OMHA 3GXHA 4R30A 2F6ZA 4KI9A 4DGPA 2A8BA 3QCIA 2HNQA 2B07A 4GE6A 4S0GA 1ECVA 1Q1MA 3OLRA 2I75A 4HJPA 3CM3A 1FPRA 2H04A 1LYVA 1JLNA 4GFUA 1PTUA 4JMKA 3ZV2A 1OEMX 5MMZB 1T4JA 3QKPA 1YTWA 2I6PA 1NZ7A 4RH9A 4ERCA 5KA8A 2F70A 2PI7A 5KA4A 3B7OA 3MOZA 4GRZA 1ZC0A 2JJDA 3F41A 2HY3A 3O4SA 1QZ0A 4MBBA 2VEYA 2E0TA 5HDEA 1C87A 2VEWA 1WCHA 1YFOA 2I3UA 3N0AA 2CNEA 1X24A 1YN9A 3BLUA 3S3HA 1ZZWA 2BIJA 3EZZA 4GS0A 1XXPA 2PSZA 5I6VA 1XXVA 2NT2A 2H4VA 2DXPA 1OHDA 4QBWA 2H4KA 1G4WR 3F81A 4OHIA 2G59A 2I5XA 1OETA 5KAAA 2BZLA 1BZHA 1PTTA 1Q6PA 3AWFA 4QBEA 4ZN5A 5KA3A 3V0IA 3GXGA 4TVVA 1PA9A 3V0FA 3ZM2A 1PYNA 1PH0A 2GP0A 3V0HA 1G7GA 2Q05A 5KA2A 1J4XA 2I6MA 3M4UA 1PA1A 2CM7A 2VEXA 2ZMMA 2Q47A 3S4OA 4H34A 1YPTA 2NT7A 4Y14A 2PQ5A 2I6IA 4NWFA 2GWOA 1JF7A 1L8GA 4HRFA 4YR8B 5KA7A 5K23A 2CMBA 2B3OA 1ZCLA 4J51A 1YGUA 2CFVA 1G1GA 1BZCA 4WU3A 2OZ5A 3D44A 2QBSA 1OHEA 1YWFA 1VHRA 2F6TA 4ICZA 3D1OA 3O5XA 2P6XA 2BGDA 1OESA 1OEVA 1ONZA 1RXDA 2BV5A 2I4EA 3QCJA 3EU0A 4PVGA 2I3RA 1U25A 3F9BA 2RF6A 3BRHA 2H02A 2QBRA 1OEOX 3QCGA 3I80A 1LQFA 5BX1A 3SMEA 1FPZA 5M43A 4PYHA 5K24A 2C46A 2CM8A 3AWGA 4IKCA 2I6OA 2QBPA 2I4HA 1C83A 2A3KA 4JMJA 2HNPA 3QCHA 1GWZA 3MOWA 4R0TA 3V0DA 4R0SA 1ONYA 2OUDA 4RH5A 1MKPA 4ZI4A 1L8KA 2F71A 3S3FA 4GWFA 2NLKA 2WGPA 2B49A 4WU2A 2J16A 1WRMA 5BUGA 5KA1A 2FJNA 3EMUA 4GRYA 1YTSA 2HXPA 1I57A 3I36A 2F6FA 2HB1A 2B4UA 1Q6JA 4RHGA 1U24A 3MMJA 1KAVA 4ZRTA 1C84A 2QCTA 1YTNA 3I7ZA 2F46A 3S4EA 3QCLA 2CNFA 2NV5A 3AWEA 2SHPA 2H4GA 1XRIA 3PS5A 5LXQB 2HVLA 3EB1A 3RZ2A 4JNBA 3SR9A 2MBCA 2OC3A 2HC1A 1FQ1A 1R6HA 3CWEA 3V0JA 1C85A 4QUNA 4GE2A 2QBQA 5J8RA 3LJ8A 2FH7A 1Q6MA 2CM2A 2I1YA 5BZXA 5EHRA 4OHEA 5GTJA 1I9SA 3S3EA 1BZJA 2I6JA 2NTAA 4GFVA 4Y2EA 2ESBA 2H03A 5K22A 1P15A 2G6ZA 2F6YA 3U96A 1C88A 2J17A 2QEPA 1PXHA 1NO6A 5EHPA 1NWLA 3V0GA 1NWEA 4YAAA 2QDCA 3QKQA 3F9AA 2QDPA 3ZM3A 2CMAA 2BGEA 1XBOA 5AWXA 4RI4A 3ZMQA 3QCBA 2CNIA 1AAXA 2CJZA 3O4UA 3NMEA 4BJOA 2PBNA 2I42A 2OOQA 2QCJA 2IMGA 1ZCKA 4GE5A 1M3GA 2AHSA 5KADA 1Q6TA 2B4SA 2M3VA 5KACA 5K9VA 4DGXA 4QAHA 3EAXA 4NNDA 2HC2A 4NX8A 5KA9A 2QDMA 4RI5A 4I8NA 3A5KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RPM A;  3S3K A;  2CMC A;  2FJM A;  2CNG A;  2PT0 A;  3ZMP A;  2PA5 A;  3A5J A;  3RO1 A;  3RGO A;  4Z6B A;  2NZ6 A;  2F6W A;  4H1O A;  1PTV A;  3BM8 A;  1V3A A;  5K9W A;  2VEU A;  1YGR A;  1PTY A;  3BLT A;  4KYR A;  3O4T A;  1EEO A;  5BZZ A;  4D3R A;  4QAP A;  2CNH A;  1YZ4 A;  1Q6N A;  2AZR A;  4QUM A;  2C7S A;  2YDU A;  2VEV A;  1WAX A;  3V0E A;  3QCN A;  1NNY A;  5K25 A;  3QCK A;  4WTY A;  4OHH A;  1GFY A;  2CM3 A;  1XM2 A;  5IBM A;  2Y2F A;  1D5R A;  1T49 A;  2GJT A;  4RKK A;  4BPC A;  2B4O A;  4RDD A;  1OEU A;  3QCC A;  3QCM A;  3H2X A;  1C86 A;  1G1H A;  4D3P A;  2HCM A;  2R0B A;  3D9C A;  4AZ1 A;  4NYH A;  1U26 A;  1G7F A;  3ZM1 A;  4HJQ A;  4D3Q A;  4OHD A;  1KAK A;  1Q6S A;  5KA0 A;  3QCD A;  1NL9 A;  3QCE A;  5KAB A;  1G4U S;  3ZM0 A;  1QXK A;  4JBC A;  5IBS A;  3RGQ A;  4WOH A;  3O3L A;  1EEN A;  1I9T A;  2ZN7 A;  3F99 A;  2I4G A;  1G1F A;  3D1H A;  2B4P A;  1LAR A;  4KYQ A;  4OHL A;  3QCF A;  4B04 A;  1T48 A;  2J16 B;  2F6V A;  1A5Y A;  3D42 A;  1OHC A;  2P4D A;  3D1Q A;  4NWG A;  1SUG A;  2Y96 A;  3OMH A;  3GXH A;  4R30 A;  2F6Z A;  4KI9 A;  4DGP A;  2A8B A;  3QCI A;  2HNQ A;  2B07 A;  4GE6 A;  4S0G A;  1ECV A;  1Q1M A;  3OLR A;  2I75 A;  4HJP A;  3CM3 A;  1FPR A;  2H04 A;  1LYV A;  1JLN A;  4GFU A;  1PTU A;  4JMK A;  3ZV2 A;  1OEM X;  5MMZ B;  1T4J A;  3QKP A;  1YTW A;  2I6P A;  1NZ7 A;  4RH9 A;  4ERC A;  5KA8 A;  2F70 A;  2PI7 A;  5KA4 A;  3B7O A;  3MOZ A;  4GRZ A;  1ZC0 A;  2JJD A;  3F41 A;  2HY3 A;  3O4S A;  1QZ0 A;  4MBB A;  2VEY A;  2E0T A;  5HDE A;  1C87 A;  2VEW A;  1WCH A;  1YFO A;  2I3U A;  3N0A A;  2CNE A;  1X24 A;  1YN9 A;  3BLU A;  3S3H A;  1ZZW A;  2BIJ A;  3EZZ A;  4GS0 A;  1XXP A;  2PSZ A;  5I6V A;  1XXV A;  2NT2 A;  2H4V A;  2DXP A;  1OHD A;  4QBW A;  2H4K A;  1G4W R;  3F81 A;  4OHI A;  2G59 A;  2I5X A;  1OET A;  5KAA A;  2BZL A;  1BZH A;  1PTT A;  1Q6P A;  3AWF A;  4QBE A;  4ZN5 A;  5KA3 A;  3V0I A;  3GXG A;  4TVV A;  1PA9 A;  3V0F A;  3ZM2 A;  1PYN A;  1PH0 A;  2GP0 A;  3V0H A;  1G7G A;  2Q05 A;  5KA2 A;  1J4X A;  2I6M A;  3M4U A;  1PA1 A;  2CM7 A;  2VEX A;  2ZMM A;  2Q47 A;  3S4O A;  4H34 A;  1YPT A;  2NT7 A;  4Y14 A;  2PQ5 A;  2I6I A;  4NWF A;  2GWO A;  1JF7 A;  1L8G A;  4HRF A;  4YR8 B;  5KA7 A;  5K23 A;  2CMB A;  2B3O A;  1ZCL A;  4J51 A;  1YGU A;  2CFV A;  1G1G A;  1BZC A;  4WU3 A;  2OZ5 A;  3D44 A;  2QBS A;  1OHE A;  1YWF A;  1VHR A;  2F6T A;  4ICZ A;  3D1O A;  3O5X A;  2P6X A;  2BGD A;  1OES A;  1OEV A;  1ONZ A;  1RXD A;  2BV5 A;  2I4E A;  3QCJ A;  3EU0 A;  4PVG A;  2I3R A;  1U25 A;  3F9B A;  2RF6 A;  3BRH A;  2H02 A;  2QBR A;  1OEO X;  3QCG A;  3I80 A;  1LQF A;  5BX1 A;  3SME A;  1FPZ A;  5M43 A;  4PYH A;  5K24 A;  2C46 A;  2CM8 A;  3AWG A;  4IKC A;  2I6O A;  2QBP A;  2I4H A;  1C83 A;  2A3K A;  4JMJ A;  2HNP A;  3QCH A;  1GWZ A;  3MOW A;  4R0T A;  3V0D A;  4R0S A;  1ONY A;  2OUD A;  4RH5 A;  1MKP A;  4ZI4 A;  1L8K A;  2F71 A;  3S3F A;  4GWF A;  2NLK A;  2WGP A;  2B49 A;  4WU2 A;  2J16 A;  1WRM A;  5BUG A;  5KA1 A;  2FJN A;  3EMU A;  4GRY A;  1YTS A;  2HXP A;  1I57 A;  3I36 A;  2F6F A;  2HB1 A;  2B4U A;  1Q6J A;  4RHG A;  1U24 A;  3MMJ A;  1KAV A;  4ZRT A;  1C84 A;  2QCT A;  1YTN A;  3I7Z A;  2F46 A;  3S4E A;  3QCL A;  2CNF A;  2NV5 A;  3AWE A;  2SHP A;  2H4G A;  1XRI A;  3PS5 A;  5LXQ B;  2HVL A;  3EB1 A;  3RZ2 A;  4JNB A;  3SR9 A;  2MBC A;  2OC3 A;  2HC1 A;  1FQ1 A;  1R6H A;  3CWE A;  3V0J A;  1C85 A;  4QUN A;  4GE2 A;  2QBQ A;  5J8R A;  3LJ8 A;  2FH7 A;  1Q6M A;  2CM2 A;  2I1Y A;  5BZX A;  5EHR A;  4OHE A;  5GTJ A;  1I9S A;  3S3E A;  1BZJ A;  2I6J A;  2NTA A;  4GFV A;  4Y2E A;  2ESB A;  2H03 A;  5K22 A;  1P15 A;  2G6Z A;  2F6Y A;  3U96 A;  1C88 A;  2J17 A;  2QEP A;  1PXH A;  1NO6 A;  5EHP A;  1NWL A;  3V0G A;  1NWE A;  4YAA A;  2QDC A;  3QKQ A;  3F9A A;  2QDP A;  3ZM3 A;  2CMA A;  2BGE A;  1XBO A;  5AWX A;  4RI4 A;  3ZMQ A;  3QCB A;  2CNI A;  1AAX A;  2CJZ A;  3O4U A;  3NME A;  4BJO A;  2PBN A;  2I42 A;  2OOQ A;  2QCJ A;  2IMG A;  1ZCK A;  4GE5 A;  1M3G A;  2AHS A;  5KAD A;  1Q6T A;  2B4S A;  2M3V A;  5KAC A;  5K9V A;  4DGX A;  4QAH A;  3EAX A;  4NND A;  2HC2 A;  4NX8 A;  5KA9 A;  2QDM A;  4RI5 A;  4I8N A;  3A5K A; 
#chains in the Genus database with same CATH topology
 1RPM A;  3S3K A;  2CMC A;  2FJM A;  3ZM5 A;  2CNG A;  2PT0 A;  3ZMP A;  2PA5 A;  3A5J A;  3RO1 A;  3RGO A;  4Z6B A;  2NZ6 A;  2Y67 A;  2F6W A;  4H1O A;  1PTV A;  3BM8 A;  1V3A A;  5K9W A;  2VEU A;  1YGR A;  1PTY A;  3BLT A;  3PYZ A;  4KYR A;  3O4T A;  1EEO A;  5BZZ A;  4D3R A;  4QAP A;  3QCZ A;  1EEH A;  2CNH A;  1YZ4 A;  1Q6N A;  2AZR A;  4QUM A;  2C7S A;  2YDU A;  2VEV A;  2AM2 A;  1WAX A;  3V0E A;  3QCN A;  1NNY A;  5K25 A;  3QCK A;  4WTY A;  4OHH A;  1GFY A;  2CM3 A;  1XM2 A;  5IBM A;  2Y2F A;  1D5R A;  1T49 A;  2GJT A;  4RKK A;  4BPC A;  4C12 A;  1W78 A;  2B4O A;  1E0D A;  4RDD A;  1OEU A;  3QCC A;  3QCM A;  3H2X A;  1C86 A;  1G1H A;  2Y1O A;  4D3P A;  2HCM A;  2R0B A;  2WJP A;  3D9C A;  4AZ1 A;  4NYH A;  1U26 A;  1G7F A;  3ZM1 A;  4HJQ A;  4D3Q A;  4OHD A;  1KAK A;  1Q6S A;  5KA0 A;  3QCD A;  1W7K A;  1NL9 A;  3QCE A;  5KAB A;  1G4U S;  3ZM0 A;  1QXK A;  4JBC A;  5IBS A;  3RGQ A;  4WOH A;  3O3L A;  1EEN A;  1I9T A;  2ZN7 A;  3F99 A;  2I4G A;  1G1F A;  3D1H A;  2B4P A;  1LAR A;  4KYQ A;  4OHL A;  3QCF A;  4B04 A;  4C13 A;  2VTE A;  1T48 A;  3N2A A;  2J16 B;  2F6V A;  1A5Y A;  3D42 A;  1OHC A;  2P4D A;  3D1Q A;  4NWG A;  1SUG A;  2Y96 A;  3OMH A;  3GXH A;  1GQY A;  4R30 A;  2F6Z A;  4KI9 A;  4DGP A;  2A8B A;  3QCI A;  2HNQ A;  1J6U A;  2B07 A;  4GE6 A;  4S0G A;  1ECV A;  1Q1M A;  3OLR A;  2I75 A;  3ZM6 A;  3NRS A;  2XJA A;  4HJP A;  3CM3 A;  1FPR A;  2H04 A;  1LYV A;  1JLN A;  4GFU A;  1PTU A;  1UAG A;  2WTZ A;  1OEM X;  4JMK A;  3ZV2 A;  1JBW A;  5MMZ B;  1T4J A;  3QKP A;  1YTW A;  2UUP A;  2I6P A;  4BUC A;  1NZ7 A;  4RH9 A;  4ERC A;  5KA8 A;  2F70 A;  2PI7 A;  5KA4 A;  1GG4 A;  3B7O A;  3MOZ A;  4GRZ A;  1ZC0 A;  2JJD A;  3F41 A;  2HY3 A;  3O4S A;  1QZ0 A;  4MBB A;  2VEY A;  2E0T A;  5HDE A;  1C87 A;  2VEW A;  1WCH A;  1YFO A;  2I3U A;  3N0A A;  2CNE A;  1X24 A;  1YN9 A;  3BLU A;  4QDI A;  1ZZW A;  3S3H A;  2BIJ A;  3EZZ A;  4GS0 A;  1XXP A;  3MVN A;  2PSZ A;  5I6V A;  1XXV A;  2NT2 A;  2H4V A;  2DXP A;  1OHD A;  4QBW A;  2H4K A;  1G4W R;  3F81 A;  4BUB A;  4OHI A;  2G59 A;  2I5X A;  1OET A;  5KAA A;  2BZL A;  1BZH A;  1PTT A;  1Q6P A;  3AWF A;  4QBE A;  4ZN5 A;  5KA3 A;  3V0I A;  3GXG A;  4TVV A;  1PA9 A;  1JBV A;  3V0F A;  3ZM2 A;  1PYN A;  1PH0 A;  2GP0 A;  3V0H A;  1G7G A;  2Q05 A;  5KA2 A;  1J4X A;  2I6M A;  3M4U A;  1PA1 A;  1GQQ A;  2CM7 A;  2VEX A;  2ZMM A;  2Q47 A;  3S4O A;  4H34 A;  1YPT A;  2NT7 A;  3LK7 A;  4Y14 A;  2VTD A;  2PQ5 A;  2I6I A;  4NWF A;  2GWO A;  1JF7 A;  1L8G A;  4HV4 A;  4HRF A;  4YR8 B;  5KA7 A;  5K23 A;  2CMB A;  4CVM A;  2B3O A;  1ZCL A;  4J51 A;  1YGU A;  2CFV A;  1G1G A;  1BZC A;  3ZL8 A;  4UAG A;  4WU3 A;  1O5Z A;  2VOR A;  2OZ5 A;  2XPC A;  3D44 A;  2QBS A;  1OHE A;  2UUO A;  1YWF A;  1VHR A;  2UAG A;  2F6T A;  4ICZ A;  1E8C A;  3D1O A;  3O5X A;  2AM1 A;  2P6X A;  2BGD A;  1OES A;  1OEV A;  1ONZ A;  1RXD A;  2BV5 A;  2I4E A;  3QCJ A;  3EU0 A;  2Y66 A;  4PVG A;  2I3R A;  1U25 A;  3F9B A;  2RF6 A;  3BRH A;  2H02 A;  2QBR A;  1OEO X;  3QCG A;  3I80 A;  1LQF A;  5BX1 A;  3SME A;  1FPZ A;  5M43 A;  4PYH A;  5K24 A;  2JFG A;  2C46 A;  2CM8 A;  3AWG A;  2VOS A;  4IKC A;  4QF5 A;  2I6O A;  2QBP A;  2I4H A;  1C83 A;  2A3K A;  4JMJ A;  2HNP A;  3QCH A;  1GWZ A;  3MOW A;  4R0T A;  3V0D A;  4R0S A;  1ONY A;  2OUD A;  4RH5 A;  1MKP A;  4ZI4 A;  1L8K A;  2F71 A;  3S3F A;  4GWF A;  2NLK A;  2WGP A;  2B49 A;  4WU2 A;  2J16 A;  1WRM A;  5BUG A;  5KA1 A;  1P31 A;  2FJN A;  3EMU A;  4GRY A;  2Y68 A;  1YTS A;  2HXP A;  1I57 A;  3I36 A;  2F6F A;  2HB1 A;  2B4U A;  2X5O A;  1Q6J A;  4RHG A;  1U24 A;  3MMJ A;  1KAV A;  4ZRT A;  1C84 A;  2QCT A;  1YTN A;  3I7Z A;  2F46 A;  3S4E A;  3QCL A;  2CNF A;  2NV5 A;  3AWE A;  2SHP A;  2H4G A;  1XRI A;  3PS5 A;  5LXQ B;  2HVL A;  3EB1 A;  3RZ2 A;  4JNB A;  3SR9 A;  2MBC A;  2OC3 A;  2HC1 A;  1FQ1 A;  1R6H A;  3CWE A;  3V0J A;  1C85 A;  4QUN A;  4GE2 A;  2QBQ A;  5J8R A;  3LJ8 A;  2FH7 A;  1Q6M A;  2CM2 A;  2I1Y A;  5BZX A;  5EHR A;  4OHE A;  5GTJ A;  1I9S A;  3HN7 A;  3S3E A;  1BZJ A;  2I6J A;  2NTA A;  4GFV A;  4Y2E A;  5A5F A;  2ESB A;  2H03 A;  5K22 A;  1P15 A;  2G6Z A;  2F6Y A;  2JFF A;  3U96 A;  1P3D A;  1C88 A;  2J17 A;  4CVK A;  2QEP A;  2GC5 A;  1PXH A;  1NO6 A;  5EHP A;  1NWL A;  1FGS A;  3V0G A;  1NWE A;  4YAA A;  2QDC A;  3QKQ A;  3F9A A;  2GC6 A;  2QDP A;  3ZM3 A;  2CMA A;  2BGE A;  1XBO A;  5AWX A;  4RI4 A;  3ZMQ A;  3QCB A;  2CNI A;  1AAX A;  2CJZ A;  3O4U A;  3NME A;  4BJO A;  2PBN A;  2GCB A;  5A5E A;  2I42 A;  2OOQ A;  2QCJ A;  2IMG A;  4ZIY A;  1ZCK A;  4GE5 A;  1M3G A;  2AHS A;  5KAD A;  1Q6T A;  2B4S A;  2M3V A;  5KAC A;  4CVL A;  5K9V A;  4DGX A;  2JFH A;  4QAH A;  3EAX A;  4NND A;  2HC2 A;  2GCA A;  4NX8 A;  3UAG A;  5KA9 A;  2QDM A;  4RI5 A;  4I8N A;  3A5K A;  2F00 A; 
#chains in the Genus database with same CATH homology
 1RPM A;  3S3K A;  2CMC A;  2FJM A;  2CNG A;  2PT0 A;  3ZMP A;  2PA5 A;  3A5J A;  3RO1 A;  3RGO A;  4Z6B A;  2NZ6 A;  2F6W A;  4H1O A;  1PTV A;  3BM8 A;  1V3A A;  5K9W A;  2VEU A;  1YGR A;  1PTY A;  3BLT A;  4KYR A;  3O4T A;  1EEO A;  5BZZ A;  4D3R A;  4QAP A;  2CNH A;  1YZ4 A;  1Q6N A;  2AZR A;  4QUM A;  2C7S A;  2YDU A;  2VEV A;  1WAX A;  3V0E A;  3QCN A;  1NNY A;  5K25 A;  3QCK A;  4WTY A;  4OHH A;  1GFY A;  2CM3 A;  1XM2 A;  5IBM A;  2Y2F A;  1D5R A;  1T49 A;  2GJT A;  4RKK A;  4BPC A;  2B4O A;  4RDD A;  1OEU A;  3QCC A;  3QCM A;  3H2X A;  1C86 A;  1G1H A;  4D3P A;  2HCM A;  2R0B A;  3D9C A;  4AZ1 A;  4NYH A;  1U26 A;  1G7F A;  3ZM1 A;  4HJQ A;  4D3Q A;  4OHD A;  1KAK A;  1Q6S A;  5KA0 A;  3QCD A;  1NL9 A;  3QCE A;  5KAB A;  1G4U S;  3ZM0 A;  1QXK A;  4JBC A;  5IBS A;  3RGQ A;  4WOH A;  3O3L A;  1EEN A;  1I9T A;  2ZN7 A;  3F99 A;  2I4G A;  1G1F A;  3D1H A;  2B4P A;  1LAR A;  4KYQ A;  4OHL A;  3QCF A;  4B04 A;  1T48 A;  2J16 B;  2F6V A;  1A5Y A;  3D42 A;  1OHC A;  2P4D A;  3D1Q A;  4NWG A;  1SUG A;  2Y96 A;  3OMH A;  3GXH A;  4R30 A;  2F6Z A;  4KI9 A;  4DGP A;  2A8B A;  3QCI A;  2HNQ A;  2B07 A;  4GE6 A;  4S0G A;  1ECV A;  1Q1M A;  3OLR A;  2I75 A;  4HJP A;  3CM3 A;  1FPR A;  2H04 A;  1LYV A;  1JLN A;  4GFU A;  1PTU A;  4JMK A;  3ZV2 A;  1OEM X;  5MMZ B;  1T4J A;  3QKP A;  1YTW A;  2I6P A;  1NZ7 A;  4RH9 A;  4ERC A;  5KA8 A;  2F70 A;  2PI7 A;  5KA4 A;  3B7O A;  3MOZ A;  4GRZ A;  1ZC0 A;  2JJD A;  3F41 A;  2HY3 A;  3O4S A;  1QZ0 A;  4MBB A;  2VEY A;  2E0T A;  5HDE A;  1C87 A;  2VEW A;  1WCH A;  1YFO A;  2I3U A;  3N0A A;  2CNE A;  1X24 A;  1YN9 A;  3BLU A;  3S3H A;  1ZZW A;  2BIJ A;  3EZZ A;  4GS0 A;  1XXP A;  2PSZ A;  5I6V A;  1XXV A;  2NT2 A;  2H4V A;  2DXP A;  1OHD A;  4QBW A;  2H4K A;  1G4W R;  3F81 A;  4OHI A;  2G59 A;  2I5X A;  1OET A;  5KAA A;  2BZL A;  1BZH A;  1PTT A;  1Q6P A;  3AWF A;  4QBE A;  4ZN5 A;  5KA3 A;  3V0I A;  3GXG A;  4TVV A;  1PA9 A;  3V0F A;  3ZM2 A;  1PYN A;  1PH0 A;  2GP0 A;  3V0H A;  1G7G A;  2Q05 A;  5KA2 A;  1J4X A;  2I6M A;  3M4U A;  1PA1 A;  2CM7 A;  2VEX A;  2ZMM A;  2Q47 A;  3S4O A;  4H34 A;  1YPT A;  2NT7 A;  4Y14 A;  2PQ5 A;  2I6I A;  4NWF A;  2GWO A;  1JF7 A;  1L8G A;  4HRF A;  4YR8 B;  5KA7 A;  5K23 A;  2CMB A;  2B3O A;  1ZCL A;  4J51 A;  1YGU A;  2CFV A;  1G1G A;  1BZC A;  4WU3 A;  2OZ5 A;  3D44 A;  2QBS A;  1OHE A;  1YWF A;  1VHR A;  2F6T A;  4ICZ A;  3D1O A;  3O5X A;  2P6X A;  2BGD A;  1OES A;  1OEV A;  1ONZ A;  1RXD A;  2BV5 A;  2I4E A;  3QCJ A;  3EU0 A;  4PVG A;  2I3R A;  1U25 A;  3F9B A;  2RF6 A;  3BRH A;  2H02 A;  2QBR A;  1OEO X;  3QCG A;  3I80 A;  1LQF A;  5BX1 A;  3SME A;  1FPZ A;  5M43 A;  4PYH A;  5K24 A;  2C46 A;  2CM8 A;  3AWG A;  4IKC A;  2I6O A;  2QBP A;  2I4H A;  1C83 A;  2A3K A;  4JMJ A;  2HNP A;  3QCH A;  1GWZ A;  3MOW A;  4R0T A;  3V0D A;  4R0S A;  1ONY A;  2OUD A;  4RH5 A;  1MKP A;  4ZI4 A;  1L8K A;  2F71 A;  3S3F A;  4GWF A;  2NLK A;  2WGP A;  2B49 A;  4WU2 A;  2J16 A;  1WRM A;  5BUG A;  5KA1 A;  2FJN A;  3EMU A;  4GRY A;  1YTS A;  2HXP A;  1I57 A;  3I36 A;  2F6F A;  2HB1 A;  2B4U A;  1Q6J A;  4RHG A;  1U24 A;  3MMJ A;  1KAV A;  4ZRT A;  1C84 A;  2QCT A;  1YTN A;  3I7Z A;  2F46 A;  3S4E A;  3QCL A;  2CNF A;  2NV5 A;  3AWE A;  2SHP A;  2H4G A;  1XRI A;  3PS5 A;  5LXQ B;  2HVL A;  3EB1 A;  3RZ2 A;  4JNB A;  3SR9 A;  2MBC A;  2OC3 A;  2HC1 A;  1FQ1 A;  1R6H A;  3CWE A;  3V0J A;  1C85 A;  4QUN A;  4GE2 A;  2QBQ A;  5J8R A;  3LJ8 A;  2FH7 A;  1Q6M A;  2CM2 A;  2I1Y A;  5BZX A;  5EHR A;  4OHE A;  5GTJ A;  1I9S A;  3S3E A;  1BZJ A;  2I6J A;  2NTA A;  4GFV A;  4Y2E A;  2ESB A;  2H03 A;  5K22 A;  1P15 A;  2G6Z A;  2F6Y A;  3U96 A;  1C88 A;  2J17 A;  2QEP A;  1PXH A;  1NO6 A;  5EHP A;  1NWL A;  3V0G A;  1NWE A;  4YAA A;  2QDC A;  3QKQ A;  3F9A A;  2QDP A;  3ZM3 A;  2CMA A;  2BGE A;  1XBO A;  5AWX A;  4RI4 A;  3ZMQ A;  3QCB A;  2CNI A;  1AAX A;  2CJZ A;  3O4U A;  3NME A;  4BJO A;  2PBN A;  2I42 A;  2OOQ A;  2QCJ A;  2IMG A;  1ZCK A;  4GE5 A;  1M3G A;  2AHS A;  5KAD A;  1Q6T A;  2B4S A;  2M3V A;  5KAC A;  5K9V A;  4DGX A;  4QAH A;  3EAX A;  4NND A;  2HC2 A;  4NX8 A;  5KA9 A;  2QDM A;  4RI5 A;  4I8N A;  3A5K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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