3ZM5A

Crystal structure of murf ligase in complex with cyanothiophene inhibitor
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
454
structure length
454
Chain Sequence
MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf.
pubmed doi rcsb
molecule keywords UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE
molecule tags Ligase
source organism Streptococcus pneumoniae r6
total genus 143
structure length 454
sequence length 454
ec nomenclature ec 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
pdb deposition date 2013-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01225 Mur_ligase Mur ligase family, catalytic domain
A PF02875 Mur_ligase_C Mur ligase family, glutamate ligase domain
A PF08245 Mur_ligase_M Mur ligase middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1190.10 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase Mur-like, catalytic domain 3zm5A02
3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 MurE/MurF, N-terminal domain 3zm5A01
3.90.190.20 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Mur ligase, C-terminal domain 3zm5A03
3HN7A 1JBVA 2GC6A 2Y66A 3UAGA 4HV4A 2Y1OA 4IHGA 3ZL8A 2UAGA 2WTZA 5A5FA 3LK7A 4E79A 1W7KA 2VTEA 3QCZA 2WJPA 3PYZA 2JFHA 2XJAA 2JFGA 3EH0A 2GCAA 4QDIA 4BUBA 2VTDA 2Y67A 2F00A 4QF5A 4CVKA 1P3DA 2Y68A 3MVNA 4C13A 2GCBA 4IHFA 4CVLA 1GQQA 3N2AA 1P31A 4CVMA 2X5OA 1EEHA 2JFFA 1J6UA 1O5ZA 2UUOA 2XPCA 2IU8A 3ZM6A 1E8CA 4IHHA 3PMOA 2VOSA 1FGSA 4UAGA 2IUAA 1UAGA 3NRSA 3EAGA 4C12A 2GC5A 1W78A 1JBWA 2AM2A 2UUPA 4E75A 1GQYA 5A5EA 2IU9A 2AM1A 4BUCA 3ZM5A 1GG4A 4ZIYA 2VORA 1E0DA
chains in the Genus database with same CATH superfamily
4IWGA 1RPMA 4JMKA 1I9TA 1LARA 2A9YA 2H03A 5EYNA 1JBVA 2GC6A 4HV4A 2CFVA 4IKCA 2R3BA 1XRIA 1WRMA 3RO1A 4DC3A 2QEPA 3D1OA 2AA0A 4R30A 3D9CA 1L8KA 2SHPA 3QCKA 1WCHA 1NL9A 1YGUA 2IMGA 1W7KA 2HC2A 4ZN5A 2NZ6A 1C3QA 2XTBA 4K8CA 2OZ5A 4E69A 1MKPA 2JFGA 2AB8A 2I6PA 3DRWA 4C5JA 3RSGA 3NL2A 3D44A 3EZZA 2B49A 3EH0A 2GCAA 4QDIA 4BUBA 3D42A 1LIIA 1KO7A 2VEXA 3RQ6A 5KA7A 4R0SA 2DDMA 5KA9A 3BRHA 3A5JA 5K24A 5C3ZA 1R6HA 3OLRA 2F00A 4N08A 3AWEA 3AWGA 3WSGA 4XF7A 3ZM2A 2I6IA 3S3FA 1LHPA 1UA4A 1P3DA 2I6BA 2I4HA 4D3RA 3O4TA 5K22A 2AZRA 1L2LA 3WSFA 2FJNA 2JGVA 3GXGA 5KA1A 3EEQA 1GWZA 4WU2A 2F6VA 3RU3A 2BZLA 1NO6A 2F6WA 2PI7A 3N2AA 2CMCA 1YZ4A 2Y2FA 5KA3A 2B4OA 5F11A 2I3UA 2FJMA 1WAXA 3RY7A 3VASA 2CNIA 1YHJA 3NL5A 5KA4A 2YXTA 3LKIA 4EBUA 5MMZB 1EEHA 2DDWA 2JFFA 1OEMX 1RXDA 3S3EA 1OEUA 4JKUA 3NBVA 3IQ0A 2DDOA 1YWFA 2NT7A 5C40A 2BIJA 3CQDA 1FGSA 2G59A 4LBXA 4O1LA 2QBSA 1RFTA 2RF6A 1KNXA 2JJDA 2CMAA 1UAGA 1NZ7A 1Q6TA 5K9VA 2HVLA 1KAVA 1YGJA 2I6JA 4C5LA 1W78A 4QUNA 3RQHA 4O1GA 5BYDA 1GQTA 1P15A 2AX3A 2AM2A 1C87A 3AWFA 5J8RA 2PKNA 1ECVA 1GC5A 2WGPA 1T4JA 5A5EA 1YN9A 5BZZA 2I5BA 2AM1A 3UQ6A 4HJQA 3ZS7A 3S4EA 1GG4A 4PYHA 3RQQA 1JF7A 3UBOA 3HYOA 2QDMA 3RSQA 5KADA 4E3AA 1LIJA 3RS8A 2F02A 3UAGA 2NT2A 3M4UA 4E8ZA 3V0FA 2ESBA 1YFOA 1C84A 1G1HA 3QCNA 5EHPA 4K8KA 2Y1OA 1PH0A 4JNBA 2GWOA 3HICA 3ZL8A 2WTZA 1AAXA 4RH9A 4Y2EA 2QBRA 5GTJA 5BUGA 4S1IA 1M3GA 2CNEA 5A5FA 4E79A 3LJSA 5KA0A 2QCVA 1C83A 4RI4A 3RRBA 2VTEA 4GRYA 3B1NA 1LIOA 3QCZA 1VK4A 3ZM3A 3NCAA 4UBEA 3NM1A 1I57A 4EOHA 4C5KA 2QDPA 1PTVA 2B3OA 1G4US 1A5YA 3NL6A 3EWMA 1Q6PA 2CM8A 2ABSA 1Q6NA 2F46A 3GXHA 4E8WA 3QCMA 3V0IA 3B3LA 2F6YA 1Q6JA 4OHHA 1U24A 2IOJA 2H4KA 4QF5A 3UQDA 1OETA 2HY3A 3ZMQA 5BYCA 1YPTA 1X24A 4CVKA 2CNFA 1PXHA 2QCJA 3QKPA 1ESJA 2VEVA 3O4SA 4GWFA 2I6MA 1LIKA 3QCCA 3HPDA 3WSEA 1OEOX 1OEVA 4IHFA 5K9WA 1TD2A 3F9BA 4CVLA 2QCTA 5M43A 4RKKA 3IN1A 4NYHA 1V3AA 2J17A 1NMOA 2NTAA 3IBQA 1T48A 1TYYA 4K9IA 3KTNA 4Z6BA 3BM8A 2I4EA 4JMJA 2VEYA 2CM7A 2I3RA 1KYHA 4QAHA 3B1PA 2DCNA 2XPCA 1PTTA 2HW1A 3ZM6A 3MOZA 1E8CA 4H1OA 1DGMA 3PMOA 4YL5A 3KZHA 2B4PA 4ZI4A 2VEUA 4GM6A 2OC3A 3NRSA 4N09A 3EU0A 1RFUA 2QBQA 2NV5A 4YWRA 5F0ZA 4I8NA 3O3LA 2GC5A 3I80A 3I7ZA 3O5XA 2JG5A 4K93A 3F81A 4KBEA 4S1MA 1XBOA 3A5KA 4S1IB 2C7SA 1NWEA 3ZM0A 2B4SA 2B4UA 5HDEA 2CNHA 4KAHA 3W4SA 1GQYA 4B04A 4ERCA 2F70A 3QKQA 4NX8A 2CJZA 5K25A 3H49A 3K9EA 2OOQA 4QAPA 3Q92A 4ZIYA 4R0TA 3WSHA 1I9SA 4LC4A 4U7XA 2FYWA 2QBPA 3EMUA 2H04A 3BGKA 2F6TA 3F99A 3QCBA 3RGQA 2F7KA 5CGAA 2PBNA 1D5RA 2I6OA 2R0BA 2Y66A 3QCEA 1UB0A 5KABA 1EKQA 3QCIA 1J4XA 3SMEA 2F6ZA 3QCJA 1FQ1A 3RPZA 2PQ5A 3FHYA 2BV5A 4KALA 4IHGA 1C85A 1RKDA 3RTCA 3CWEA 4GFVA 2F71A 4RH5A 1YTSA 2DXPA 3NMEA 1RFVA 5KA2A 3SR9A 3BLTA 1JXIA 3MOWA 4QBEA 2Q05A 3V0DA 1VHRA 2V78A 4XDAA 2C49A 2FH7A 2WJPA 3RTAA 3PYZA 1NMPA 1JLNA 2XJAA 2J16B 1ZCKA 4JJPA 3S4OA 1RK2A 4JBCA 3UMOA 5K23A 4OHLA 2AJPA 1VM7A 4J51A 4C5NA 3NC9A 2YXUA 4OHIA 1G1GA 2PKKA 2I75A 3QCHA 5KACA 3IKHA 4BPCA 1L8GA 5C41A 1QXKA 2CNGA 1SUGA 3B1OA 4D3PA 1BZHA 3VAQA 4HRFA 4K8PA 4PVGA 2VARA 2Y68A 3OTXA 1ONYA 1NNYA 3RREA 3V0EA 1PA9A 1U25A 3H74A 1ESQA 3MVNA 2HNPA 3MMJA 3RT7A 2HNQA 4RI5A 2GCBA 3B7OA 1PTUA 3RTDA 3L31A 2QDCA 2ABQA 2AHSA 1GQQA 1BZCA 4KYQA 5LXQB 2JG1A 4CVMA 3RM5A 4OHEA 1V1AA 4NWFA 1BX4A 3KEUA 3RTGA 3Q1YA 3CM3A 3JULA 3RRJA 3LOOA 1V19A 2FV7A 3RTEA 2Q47A 1LYVA 2UUOA 3B1RA 1OHDA 4QBWA 2IU8A 2MBCA 1U26A 1XXVA 3B1QA 3RTBA 1ONZA 4H34A 3O4UA 4UAGA 4TVVA 2CMBA 3DZVA 1V1BA 2HQQA 4NWGA 2J16A 4DGPA 2HC1A 4GFUA 3D1HA 5CM5A 5IBSA 4YR8B 1G7FA 3IE7A 1YGRA 1BZJA 2C4EA 2AWDA 3U96A 1JBWA 2I4GA 3NL3A 3N1CA 1GFYA 3F41A 4ZRTA 4MBBA 2UUPA 4IWMA 1TZ6A 3FHXA 2C46A 3ZMPA 5KA8A 4BUCA 4GRZA 3V0HA 5BYFA 4BJOA 1C88A 4KADA 4X8FA 3QA2A 3BF5A 2CM2A 2A8BA 3PZSA 1E0DA 3L2BA 1XXPA 2HB1A 3ZV2A 5COJA 5C3YA 1EENA 5KAAA 1VI9A 3PL2A 4C5MA 3HN7A 2PA5A 2YYBA 4E84A 4HJPA 1EEOA 3D1QA 2I42A 5EY7A 3LHXA 4QUMA 2CM3A 4WOHA 3NBWA 1V1SA 4KI9A 3RQXA 2UAGA 1OHEA 3BLUA 3IH0A 5CGEA 1U2XA 3PS5A 5TQIA 4GS0A 4RHGA 3QCGA 5TRWA 3NC2A 3RRFA 1RKSA 3LK7A 4AZ1A 2HXPA 2H4GA 3WSIA 2I5XA 3RQ8A 1FPRA 2A9ZA 5BX1A 4WJMA 2JFHA 4K9CA 3RPHA 4DU5A 4OHDA 3I36A 2QHPA 3EAXA 2M3VA 3MBHA 4KYRA 1PTYA 1EKKA 3UQEA 4WU3A 3RZ2A 1FPZA 3RO4A 2VTDA 3NM3A 1G4WR 2BGDA 2Y67A 4YAAA 3RS9A 4S1HA 2PKFA 1QZ0A 4XCKA 3RU2A 3ZM1A 2VEWA 1OHCA 1YTNA 1G7GA 1T49A 4GE6A 3UMPA 1NWLA 4LCAA 1XM2A 4WTYA 3OMHA 4NNDA 2I6AA 1RKAA 5IBMA 1PA1A 1Q6SA 4K8TA 3HJ6A 3GO6A 2R3EA 4C13A 4EN4A 3GBUA 2PSZA 4E8YA 2G6ZA 2AFBA 4B8RA 4GE2A 3S3HA 2GJTA 2P6XA 1P31A 3N0AA 2HCMA 2NLKA 2A3KA 3GO7A 2Q5RA 4RDDA 2H4VA 1Q6MA 2RBCA 4KANA 2X5OA 3QAIA 1ZZWA 3EB1A 4Y14A 1LHRA 1J6UA 2YDUA 4GE5A 3H2XA 4D3QA 4S0GA 1O5ZA 2ZMMA 3MBJA 3K5WA 2OUDA 2B07A 2AJRA 2PKMA 4IHHA 2BGEA 2HLZA 2VOSA 3V0JA 4B8SA 2IUAA 5BYEA 2GP0A 3RQ2A 1ZCLA 1KAKA 1WYEA 3EAGA 3RSSA 2P4DA 1G1FA 4XF6A 3LJ8A 4ICZA 4C12A 5BZXA 1Q1MA 3UQ9A 2NWHA 4JKSA 4PVVA 4LBGA 1OESA 2F6FA 3RSFA 2Y96A 3QCLA 2I1YA 5I6VA 2E0TA 3QCDA 4E75A 1JXHA 3I3YA 1PYNA 2H02A 1C86A 2PT0A 3QCFA 2IU9A 3V0GA 3RQ5A 3ZM5A 1LQFA 3KD6A 3RT9A 3F9AA 5AWXA 3S3KA 3RGOA 1TZ3A 1ZC0A 3WSDA 1YGKA 2VORA 4EUMA 4DGXA 1YTWA 5B6AA 2ZN7A 5EHRA
chains in the Genus database with same CATH topology
3HN7A 1JBVA 2GC6A 2Y66A 3UAGA 4HV4A 2Y1OA 4IHGA 3ZL8A 2UAGA 2WTZA 5A5FA 3LK7A 4E79A 1W7KA 2VTEA 3QCZA 2WJPA 3PYZA 2JFHA 2XJAA 2JFGA 3EH0A 2GCAA 4QDIA 4BUBA 2VTDA 2Y67A 2F00A 4QF5A 4CVKA 1P3DA 2Y68A 3MVNA 4C13A 2GCBA 4IHFA 4CVLA 1GQQA 3N2AA 1P31A 4CVMA 2X5OA 1EEHA 2JFFA 1J6UA 1O5ZA 2UUOA 2XPCA 2IU8A 3ZM6A 1E8CA 4IHHA 3PMOA 2VOSA 1FGSA 4UAGA 2IUAA 1UAGA 3NRSA 3EAGA 4C12A 2GC5A 1W78A 1JBWA 2AM2A 2UUPA 4E75A 1GQYA 5A5EA 2IU9A 2AM1A 4BUCA 3ZM5A 1GG4A 4ZIYA 2VORA 1E0DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HN7 A;  1JBV A;  2GC6 A;  2Y66 A;  3UAG A;  4HV4 A;  2Y1O A;  4IHG A;  3ZL8 A;  2UAG A;  2WTZ A;  5A5F A;  3LK7 A;  4E79 A;  1W7K A;  2VTE A;  3QCZ A;  2WJP A;  3PYZ A;  2JFH A;  2XJA A;  2JFG A;  3EH0 A;  2GCA A;  4QDI A;  4BUB A;  2VTD A;  2Y67 A;  2F00 A;  4QF5 A;  4CVK A;  1P3D A;  2Y68 A;  3MVN A;  4C13 A;  2GCB A;  4IHF A;  4CVL A;  1GQQ A;  3N2A A;  1P31 A;  4CVM A;  2X5O A;  1EEH A;  2JFF A;  1J6U A;  1O5Z A;  2UUO A;  2XPC A;  2IU8 A;  3ZM6 A;  1E8C A;  4IHH A;  3PMO A;  2VOS A;  1FGS A;  4UAG A;  2IUA A;  1UAG A;  3NRS A;  3EAG A;  4C12 A;  2GC5 A;  1W78 A;  1JBW A;  2AM2 A;  2UUP A;  4E75 A;  1GQY A;  5A5E A;  2IU9 A;  2AM1 A;  4BUC A;  3ZM5 A;  1GG4 A;  4ZIY A;  2VOR A;  1E0D A; 
#chains in the Genus database with same CATH topology
 4IWG A;  1RPM A;  4JMK A;  1I9T A;  1LAR A;  2A9Y A;  2H03 A;  5EYN A;  1JBV A;  2GC6 A;  4HV4 A;  2CFV A;  4IKC A;  2R3B A;  1XRI A;  1WRM A;  3RO1 A;  4DC3 A;  2QEP A;  3D1O A;  2AA0 A;  4R30 A;  3D9C A;  1L8K A;  2SHP A;  3QCK A;  1WCH A;  1NL9 A;  1YGU A;  2IMG A;  1W7K A;  2HC2 A;  4ZN5 A;  2NZ6 A;  1C3Q A;  2XTB A;  4K8C A;  2OZ5 A;  4E69 A;  1MKP A;  2JFG A;  2AB8 A;  2I6P A;  3DRW A;  4C5J A;  3RSG A;  3NL2 A;  3D44 A;  3EZZ A;  2B49 A;  3EH0 A;  2GCA A;  4QDI A;  4BUB A;  3D42 A;  1LII A;  1KO7 A;  2VEX A;  3RQ6 A;  5KA7 A;  4R0S A;  2DDM A;  5KA9 A;  3BRH A;  3A5J A;  5K24 A;  5C3Z A;  1R6H A;  3OLR A;  2F00 A;  4N08 A;  3AWE A;  3AWG A;  3WSG A;  4XF7 A;  3ZM2 A;  2I6I A;  3S3F A;  1LHP A;  1UA4 A;  1P3D A;  2I6B A;  2I4H A;  4D3R A;  3O4T A;  5K22 A;  2AZR A;  1L2L A;  3WSF A;  2FJN A;  2JGV A;  3GXG A;  5KA1 A;  3EEQ A;  1GWZ A;  4WU2 A;  2F6V A;  3RU3 A;  2BZL A;  1NO6 A;  2F6W A;  2PI7 A;  3N2A A;  2CMC A;  1YZ4 A;  2Y2F A;  5KA3 A;  2B4O A;  5F11 A;  2I3U A;  2FJM A;  1WAX A;  3RY7 A;  3VAS A;  2CNI A;  1YHJ A;  3NL5 A;  5KA4 A;  2YXT A;  3LKI A;  4EBU A;  5MMZ B;  1EEH A;  2DDW A;  2JFF A;  1OEM X;  1RXD A;  3S3E A;  1OEU A;  4JKU A;  3NBV A;  3IQ0 A;  2DDO A;  1YWF A;  2NT7 A;  5C40 A;  2BIJ A;  3CQD A;  1FGS A;  2G59 A;  4LBX A;  4O1L A;  2QBS A;  1RFT A;  2RF6 A;  1KNX A;  2JJD A;  2CMA A;  1UAG A;  1NZ7 A;  1Q6T A;  5K9V A;  2HVL A;  1KAV A;  1YGJ A;  2I6J A;  4C5L A;  1W78 A;  4QUN A;  3RQH A;  4O1G A;  5BYD A;  1GQT A;  1P15 A;  2AX3 A;  2AM2 A;  1C87 A;  3AWF A;  5J8R A;  2PKN A;  1ECV A;  1GC5 A;  2WGP A;  1T4J A;  5A5E A;  1YN9 A;  5BZZ A;  2I5B A;  2AM1 A;  3UQ6 A;  4HJQ A;  3ZS7 A;  3S4E A;  1GG4 A;  4PYH A;  3RQQ A;  1JF7 A;  3UBO A;  3HYO A;  2QDM A;  3RSQ A;  5KAD A;  4E3A A;  1LIJ A;  3RS8 A;  2F02 A;  3UAG A;  2NT2 A;  3M4U A;  4E8Z A;  3V0F A;  2ESB A;  1YFO A;  1C84 A;  1G1H A;  3QCN A;  5EHP A;  4K8K A;  2Y1O A;  1PH0 A;  4JNB A;  2GWO A;  3HIC A;  3ZL8 A;  2WTZ A;  1AAX A;  4RH9 A;  4Y2E A;  2QBR A;  5GTJ A;  5BUG A;  4S1I A;  1M3G A;  2CNE A;  5A5F A;  4E79 A;  3LJS A;  5KA0 A;  2QCV A;  1C83 A;  4RI4 A;  3RRB A;  2VTE A;  4GRY A;  3B1N A;  1LIO A;  3QCZ A;  1VK4 A;  3ZM3 A;  3NCA A;  4UBE A;  3NM1 A;  1I57 A;  4EOH A;  4C5K A;  2QDP A;  1PTV A;  2B3O A;  1G4U S;  1A5Y A;  3NL6 A;  3EWM A;  1Q6P A;  2CM8 A;  2ABS A;  1Q6N A;  2F46 A;  3GXH A;  4E8W A;  3QCM A;  3V0I A;  3B3L A;  2F6Y A;  1Q6J A;  4OHH A;  1U24 A;  2IOJ A;  2H4K A;  4QF5 A;  3UQD A;  1OET A;  2HY3 A;  3ZMQ A;  5BYC A;  1YPT A;  1X24 A;  4CVK A;  2CNF A;  1PXH A;  2QCJ A;  3QKP A;  1ESJ A;  2VEV A;  3O4S A;  4GWF A;  2I6M A;  1LIK A;  3QCC A;  3HPD A;  3WSE A;  1OEO X;  1OEV A;  4IHF A;  5K9W A;  1TD2 A;  3F9B A;  4CVL A;  2QCT A;  5M43 A;  4RKK A;  3IN1 A;  4NYH A;  1V3A A;  2J17 A;  1NMO A;  2NTA A;  3IBQ A;  1T48 A;  1TYY A;  4K9I A;  3KTN A;  4Z6B A;  3BM8 A;  2I4E A;  4JMJ A;  2VEY A;  2CM7 A;  2I3R A;  1KYH A;  4QAH A;  3B1P A;  2DCN A;  2XPC A;  1PTT A;  2HW1 A;  3ZM6 A;  3MOZ A;  1E8C A;  4H1O A;  1DGM A;  3PMO A;  4YL5 A;  3KZH A;  2B4P A;  4ZI4 A;  2VEU A;  4GM6 A;  2OC3 A;  3NRS A;  4N09 A;  3EU0 A;  1RFU A;  2QBQ A;  2NV5 A;  4YWR A;  5F0Z A;  4I8N A;  3O3L A;  2GC5 A;  3I80 A;  3I7Z A;  3O5X A;  2JG5 A;  4K93 A;  3F81 A;  4KBE A;  4S1M A;  1XBO A;  3A5K A;  4S1I B;  2C7S A;  1NWE A;  3ZM0 A;  2B4S A;  2B4U A;  5HDE A;  2CNH A;  4KAH A;  3W4S A;  1GQY A;  4B04 A;  4ERC A;  2F70 A;  3QKQ A;  4NX8 A;  2CJZ A;  5K25 A;  3H49 A;  3K9E A;  2OOQ A;  4QAP A;  3Q92 A;  4ZIY A;  4R0T A;  3WSH A;  1I9S A;  4LC4 A;  4U7X A;  2FYW A;  2QBP A;  3EMU A;  2H04 A;  3BGK A;  2F6T A;  3F99 A;  3QCB A;  3RGQ A;  2F7K A;  5CGA A;  2PBN A;  1D5R A;  2I6O A;  2R0B A;  2Y66 A;  3QCE A;  1UB0 A;  5KAB A;  1EKQ A;  3QCI A;  1J4X A;  3SME A;  2F6Z A;  3QCJ A;  1FQ1 A;  3RPZ A;  2PQ5 A;  3FHY A;  2BV5 A;  4KAL A;  4IHG A;  1C85 A;  1RKD A;  3RTC A;  3CWE A;  4GFV A;  2F71 A;  4RH5 A;  1YTS A;  2DXP A;  3NME A;  1RFV A;  5KA2 A;  3SR9 A;  3BLT A;  1JXI A;  3MOW A;  4QBE A;  2Q05 A;  3V0D A;  1VHR A;  2V78 A;  4XDA A;  2C49 A;  2FH7 A;  2WJP A;  3RTA A;  3PYZ A;  1NMP A;  1JLN A;  2XJA A;  2J16 B;  1ZCK A;  4JJP A;  3S4O A;  1RK2 A;  4JBC A;  3UMO A;  5K23 A;  4OHL A;  2AJP A;  1VM7 A;  4J51 A;  4C5N A;  3NC9 A;  2YXU A;  4OHI A;  1G1G A;  2PKK A;  2I75 A;  3QCH A;  5KAC A;  3IKH A;  4BPC A;  1L8G A;  5C41 A;  1QXK A;  2CNG A;  1SUG A;  3B1O A;  4D3P A;  1BZH A;  3VAQ A;  4HRF A;  4K8P A;  4PVG A;  2VAR A;  2Y68 A;  3OTX A;  1ONY A;  1NNY A;  3RRE A;  3V0E A;  1PA9 A;  1U25 A;  3H74 A;  1ESQ A;  3MVN A;  2HNP A;  3MMJ A;  3RT7 A;  2HNQ A;  4RI5 A;  2GCB A;  3B7O A;  1PTU A;  3RTD A;  3L31 A;  2QDC A;  2ABQ A;  2AHS A;  1GQQ A;  1BZC A;  4KYQ A;  5LXQ B;  2JG1 A;  4CVM A;  3RM5 A;  4OHE A;  1V1A A;  4NWF A;  1BX4 A;  3KEU A;  3RTG A;  3Q1Y A;  3CM3 A;  3JUL A;  3RRJ A;  3LOO A;  1V19 A;  2FV7 A;  3RTE A;  2Q47 A;  1LYV A;  2UUO A;  3B1R A;  1OHD A;  4QBW A;  2IU8 A;  2MBC A;  1U26 A;  1XXV A;  3B1Q A;  3RTB A;  1ONZ A;  4H34 A;  3O4U A;  4UAG A;  4TVV A;  2CMB A;  3DZV A;  1V1B A;  2HQQ A;  4NWG A;  2J16 A;  4DGP A;  2HC1 A;  4GFU A;  3D1H A;  5CM5 A;  5IBS A;  4YR8 B;  1G7F A;  3IE7 A;  1YGR A;  1BZJ A;  2C4E A;  2AWD A;  3U96 A;  1JBW A;  2I4G A;  3NL3 A;  3N1C A;  1GFY A;  3F41 A;  4ZRT A;  4MBB A;  2UUP A;  4IWM A;  1TZ6 A;  3FHX A;  2C46 A;  3ZMP A;  5KA8 A;  4BUC A;  4GRZ A;  3V0H A;  5BYF A;  4BJO A;  1C88 A;  4KAD A;  4X8F A;  3QA2 A;  3BF5 A;  2CM2 A;  2A8B A;  3PZS A;  1E0D A;  3L2B A;  1XXP A;  2HB1 A;  3ZV2 A;  5COJ A;  5C3Y A;  1EEN A;  5KAA A;  1VI9 A;  3PL2 A;  4C5M A;  3HN7 A;  2PA5 A;  2YYB A;  4E84 A;  4HJP A;  1EEO A;  3D1Q A;  2I42 A;  5EY7 A;  3LHX A;  4QUM A;  2CM3 A;  4WOH A;  3NBW A;  1V1S A;  4KI9 A;  3RQX A;  2UAG A;  1OHE A;  3BLU A;  3IH0 A;  5CGE A;  1U2X A;  3PS5 A;  5TQI A;  4GS0 A;  4RHG A;  3QCG A;  5TRW A;  3NC2 A;  3RRF A;  1RKS A;  3LK7 A;  4AZ1 A;  2HXP A;  2H4G A;  3WSI A;  2I5X A;  3RQ8 A;  1FPR A;  2A9Z A;  5BX1 A;  4WJM A;  2JFH A;  4K9C A;  3RPH A;  4DU5 A;  4OHD A;  3I36 A;  2QHP A;  3EAX A;  2M3V A;  3MBH A;  4KYR A;  1PTY A;  1EKK A;  3UQE A;  4WU3 A;  3RZ2 A;  1FPZ A;  3RO4 A;  2VTD A;  3NM3 A;  1G4W R;  2BGD A;  2Y67 A;  4YAA A;  3RS9 A;  4S1H A;  2PKF A;  1QZ0 A;  4XCK A;  3RU2 A;  3ZM1 A;  2VEW A;  1OHC A;  1YTN A;  1G7G A;  1T49 A;  4GE6 A;  3UMP A;  1NWL A;  4LCA A;  1XM2 A;  4WTY A;  3OMH A;  4NND A;  2I6A A;  1RKA A;  5IBM A;  1PA1 A;  1Q6S A;  4K8T A;  3HJ6 A;  3GO6 A;  2R3E A;  4C13 A;  4EN4 A;  3GBU A;  2PSZ A;  4E8Y A;  2G6Z A;  2AFB A;  4B8R A;  4GE2 A;  3S3H A;  2GJT A;  2P6X A;  1P31 A;  3N0A A;  2HCM A;  2NLK A;  2A3K A;  3GO7 A;  2Q5R A;  4RDD A;  2H4V A;  1Q6M A;  2RBC A;  4KAN A;  2X5O A;  3QAI A;  1ZZW A;  3EB1 A;  4Y14 A;  1LHR A;  1J6U A;  2YDU A;  4GE5 A;  3H2X A;  4D3Q A;  4S0G A;  1O5Z A;  2ZMM A;  3MBJ A;  3K5W A;  2OUD A;  2B07 A;  2AJR A;  2PKM A;  4IHH A;  2BGE A;  2HLZ A;  2VOS A;  3V0J A;  4B8S A;  2IUA A;  5BYE A;  2GP0 A;  3RQ2 A;  1ZCL A;  1KAK A;  1WYE A;  3EAG A;  3RSS A;  2P4D A;  1G1F A;  4XF6 A;  3LJ8 A;  4ICZ A;  4C12 A;  5BZX A;  1Q1M A;  3UQ9 A;  2NWH A;  4JKS A;  4PVV A;  4LBG A;  1OES A;  2F6F A;  3RSF A;  2Y96 A;  3QCL A;  2I1Y A;  5I6V A;  2E0T A;  3QCD A;  4E75 A;  1JXH A;  3I3Y A;  1PYN A;  2H02 A;  1C86 A;  2PT0 A;  3QCF A;  2IU9 A;  3V0G A;  3RQ5 A;  3ZM5 A;  1LQF A;  3KD6 A;  3RT9 A;  3F9A A;  5AWX A;  3S3K A;  3RGO A;  1TZ3 A;  1ZC0 A;  3WSD A;  1YGK A;  2VOR A;  4EUM A;  4DGX A;  1YTW A;  5B6A A;  2ZN7 A;  5EHR A; 
#chains in the Genus database with same CATH homology
 3HN7 A;  1JBV A;  2GC6 A;  2Y66 A;  3UAG A;  4HV4 A;  2Y1O A;  4IHG A;  3ZL8 A;  2UAG A;  2WTZ A;  5A5F A;  3LK7 A;  4E79 A;  1W7K A;  2VTE A;  3QCZ A;  2WJP A;  3PYZ A;  2JFH A;  2XJA A;  2JFG A;  3EH0 A;  2GCA A;  4QDI A;  4BUB A;  2VTD A;  2Y67 A;  2F00 A;  4QF5 A;  4CVK A;  1P3D A;  2Y68 A;  3MVN A;  4C13 A;  2GCB A;  4IHF A;  4CVL A;  1GQQ A;  3N2A A;  1P31 A;  4CVM A;  2X5O A;  1EEH A;  2JFF A;  1J6U A;  1O5Z A;  2UUO A;  2XPC A;  2IU8 A;  3ZM6 A;  1E8C A;  4IHH A;  3PMO A;  2VOS A;  1FGS A;  4UAG A;  2IUA A;  1UAG A;  3NRS A;  3EAG A;  4C12 A;  2GC5 A;  1W78 A;  1JBW A;  2AM2 A;  2UUP A;  4E75 A;  1GQY A;  5A5E A;  2IU9 A;  2AM1 A;  4BUC A;  3ZM5 A;  1GG4 A;  4ZIY A;  2VOR A;  1E0D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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