3ZM6A

Crystal structure of murf ligase in complex with cyanothiophene inhibitor
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
454
structure length
454
Chain Sequence
MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Ligase
molecule keywords UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE
total genus 161
structure length 454
sequence length 454
ec nomenclature ec 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
pdb deposition date 2013-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01225 Mur_ligase Mur ligase family, catalytic domain
A PF02875 Mur_ligase_C Mur ligase family, glutamate ligase domain
A PF08245 Mur_ligase_M Mur ligase middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1190.10 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase Mur-like, catalytic domain 3zm6A02
3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 MurE/MurF, N-terminal domain 3zm6A01
3.90.190.20 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Mur ligase, C-terminal domain 3zm6A03
2Y68A 4IHFA 4E75A 3PYZA 2WJPA 2Y1OA 1P3DA 1E8CA 3UAGA 3MVNA 2IU8A 4QDIA 1O5ZA 2VTEA 2GCAA 4UAGA 2UAGA 2GC5A 2GC6A 2IUAA 1J6UA 2VTDA 2AM1A 1EEHA 1E0DA 2X5OA 2Y67A 4ZIYA 1JBVA 2VOSA 4BUCA 3ZL8A 1GQQA 2JFGA 2UUPA 2GCBA 5A5EA 4CVKA 4HV4A 4CVMA 3PMOA 1W7KA 2JFHA 1GQYA 4IHGA 2F00A 2JFFA 3HN7A 2Y66A 1P31A 3ZM6A 3EH0A 4BUBA 4C13A 4IHHA 2XJAA 2IU9A 2AM2A 2VORA 4CVLA 1W78A 4QF5A 3QCZA 5A5FA 1GG4A 4C12A 2XPCA 3EAGA 4E79A 1UAGA 2WTZA 1JBWA 2UUOA 3ZM5A 3LK7A 1FGSA 3NRSA 3N2AA
chains in the Genus database with same CATH superfamily
3SR9A 1OEVA 3ZMPA 2Y1OA 1LIKA 4YWRA 2VTEA 1OESA 1PYNA 1Q6MA 4DGPA 1UB0A 1C84A 1JLNA 4WU2A 4XF6A 1GC5A 1PTTA 2IUAA 1J6UA 5EY7A 3RO1A 2PT0A 1UA4A 1FPZA 3QCBA 4I8NA 3V0JA 2F7KA 3UQDA 5A5EA 3RQQA 3RTGA 5KA1A 4HRFA 2R3EA 1C87A 5COJA 3EMUA 3OTXA 2I6AA 2XTBA 5BYDA 1V3AA 2CNFA 1KYHA 1EKQA 3EAGA 2AWDA 3PS5A 4GE5A 4YAAA 4IWMA 1PA1A 2WJPA 2CM8A 2PSZA 3WSIA 4GE2A 3EU0A 3QCJA 4S1HA 2ZN7A 4KALA 2A3KA 3RRJA 4QBEA 3ZMQA 2YXTA 5EHRA 3QCEA 2I6OA 3QCGA 5BZXA 4GRYA 1ZCLA 4ZIYA 2B3OA 2F6YA 3RQ5A 3B3LA 1ECVA 2GWOA 3O4SA 2F6WA 4Y14A 5BUGA 2Y66A 3LJSA 4R30A 4ZRTA 2AM2A 3LKIA 2DDOA 2I6MA 4NX8A 1PTVA 3ZM1A 1W78A 3B1NA 2BGEA 3NC9A 4GS0A 2PKFA 4QUNA 2I4EA 2H4GA 3D9CA 4IHFA 3OLRA 3GBUA 5K22A 3B1QA 2I3RA 2R0BA 5KABA 2QHPA 2FV7A 3A5JA 1YGKA 1T4JA 4BPCA 4C5LA 4S1IA 3NM3A 1Q6PA 3CQDA 1JXHA 4YR8B 1XRIA 5KA3A 3RTEA 2QDCA 1W7KA 1V1AA 2JFFA 2I5BA 1JXIA 4ZN5A 2AHSA 3IKHA 3CM3A 3MOZA 2YDUA 3RT7A 4E8WA 4N09A 1EEOA 2QBPA 4JMKA 5I6VA 3RS8A 2V78A 2NV5A 1XXPA 1A5YA 4XF7A 4WJMA 1VM7A 2Q47A 5LXQB 4N08A 2BZLA 4JBCA 4DGXA 4OHEA 2VEYA 2OC3A 4BJOA 3BGKA 1YGUA 2ABSA 3JULA 3RSGA 2I6BA 3L31A 1RK2A 1MKPA 2NZ6A 1NMPA 5CGAA 2AFBA 3LJ8A 3UMOA 2X5OA 3IN1A 2F70A 1JBVA 5M43A 2HC2A 3PMOA 2JFGA 3UQEA 2P6XA 1WCHA 1M3GA 3MOWA 4HJPA 2GP0A 1GFYA 4GM6A 3L2BA 3B1PA 2P4DA 4IHHA 3RGOA 3QCMA 2AX3A 3QCZA 1I9TA 3QCLA 4C12A 1ONZA 4MBBA 4E79A 1C83A 2UUOA 3H74A 2CMCA 2I5XA 4IKCA 1C86A 4RI4A 1KNXA 2CM3A 3M4UA 1EKKA 2PI7A 1LHRA 3PL2A 2BIJA 1AAXA 1TD2A 4K9IA 2QDMA 3V0GA 5KA0A 1TZ3A 1RPMA 1LIOA 2C4EA 1VI9A 2VEVA 4E84A 3UQ9A 4RI5A 1QZ0A 2F00A 4O1LA 2F6TA 1I9SA 1RKAA 4R0SA 3K5WA 3QCDA 1TZ6A 2PKNA 3BRHA 5EHPA 5J8RA 3F9BA 4RH5A 3ZM0A 4D3QA 3LOOA 1C85A 3IE7A 2AA0A 4RKKA 2VEWA 4C5MA 4U7XA 4UAGA 3GO7A 3RS9A 2HNQA 5TQIA 4EBUA 2YXUA 1FPRA 4ERCA 1OHEA 3QKQA 2IMGA 2QDPA 4K8KA 4ICZA 2UUPA 1Q6JA 4JNBA 4JMJA 2CM7A 1OHDA 5KA8A 5K25A 2B07A 3RSSA 1G4US 2NT7A 4OHLA 3WSGA 1J4XA 3D44A 3D1QA 1YHJA 2I4GA 2MBCA 3EZZA 2A9ZA 1NL9A 4B04A 3PZSA 2WTZA 1JBWA 2VARA 1I57A 3UBOA 5K23A 1G1GA 1C3QA 3RSQA 4GFVA 2PKKA 4J51A 3S4EA 3Q1YA 4NNDA 1GWZA 4S1MA 5MMZB 1VHRA 3ZS7A 3BLTA 1OHCA 2CNHA 2QBSA 4BUCA 2CM2A 2B4UA 3RQ2A 1GQQA 4KBEA 3RQHA 4GRZA 3UQ6A 2G59A 4KADA 3HN7A 2J16A 1PTUA 4C13A 2IU9A 1U25A 5TRWA 3FHYA 4C5KA 2VORA 4QF5A 2HLZA 4E69A 1QXKA 1YN9A 3F9AA 2NWHA 5C40A 3CWEA 3RTDA 5BYEA 4IWGA 4D3RA 3LHXA 3NL6A 2GJTA 3O3LA 1Q6TA 4QAHA 1FQ1A 1ONYA 2HXPA 2I6PA 3AWGA 1PTYA 3NMEA 2DDMA 4IHGA 4CVMA 2G6ZA 1YZ4A 4YL5A 3H2XA 2FH7A 5BX1A 3FHXA 3N0AA 3RRBA 2Q05A 1L8KA 3F81A 2AB8A 5BYCA 1OEOX 1NWLA 3QCNA 2SHPA 2WGPA 1FGSA 5KACA 1LARA 2HB1A 3RTCA 3NL2A 4K93A 1R6HA 2CNEA 2QCJA 2QCVA 3MVNA 1EENA 3HJ6A 1G7FA 4K8PA 3RGQA 2HY3A 2DCNA 1LHPA 2I1YA 3KD6A 4KANA 2JG5A 5CGEA 4GFUA 3IBQA 2QCTA 1ZZWA 5KA7A 5GTJA 1OETA 1YGJA 2Y67A 1NNYA 4PVGA 4H1OA 5AWXA 1T48A 1ZC0A 2I3UA 1G1HA 4DC3A 4GE6A 3NBVA 2ESBA 4PVVA 1XXVA 3IQ0A 4NWGA 2C49A 4OHHA 5C3ZA 1RKDA 3DRWA 3KTNA 5KAAA 2E0TA 5CM5A 2I4HA 4DU5A 3H49A 5C41A 2CFVA 3AWFA 2PQ5A 2HCMA 3GXGA 4E8ZA 4TVVA 1OEMX 3GO6A 2C46A 1KO7A 1PA9A 4H34A 1YTWA 4KI9A 3A5KA 2AJRA 5IBMA 1YGRA 1NMOA 3S3KA 1ESQA 2H04A 2F71A 2VOSA 3RPZA 2A9YA 2GCBA 2Y2FA 3BM8A 1YFOA 3VASA 2H4VA 2I6JA 5KA4A 4EUMA 3ZM6A 2JG1A 3AWEA 3O5XA 1BZHA 1NO6A 3W4SA 4Z6BA 2OUDA 2JJDA 2XPCA 2B4OA 1UAGA 3OMHA 3ZL8A 2H03A 3I3YA 1NWEA 4QAPA 1ESJA 3EAXA 4LBGA 3F99A 5BZZA 2IU8A 4QDIA 3RRFA 3S4OA 1RFTA 4C5NA 3V0HA 1Q6SA 2CNGA 1KAVA 2HC1A 3RY7A 3QCKA 3I7ZA 2FJNA 3UMPA 2BGDA 1U2XA 2NT2A 2R3BA 4B8RA 2PKMA 5BYFA 4PYHA 3ZM3A 4S0GA 1Q6NA 3S3FA 3Q92A 2XJAA 1V19A 3V0DA 2BV5A 3K9EA 3RTBA 3QAIA 4LCAA 3EB1A 1RXDA 3RU2A 3NRSA 3RM5A 2I42A 1GQTA 1P15A 1TYYA 2B4PA 3SMEA 1U24A 2M3VA 3EWMA 4XDAA 3WSEA 2UAGA 2GC5A 3B1RA 5C3YA 1NZ7A 2I6IA 2J16B 1OEUA 1EEHA 3RT9A 4JKUA 5B6AA 3NM1A 3WSDA 4Y2EA 3B7OA 3EEQA 3D1HA 1LIJA 2FYWA 2HW1A 3MMJA 3QCFA 3S3HA 1ZCKA 1P31A 2PBNA 3EH0A 4ZI4A 5F0ZA 4AZ1A 1SUGA 3RZ2A 5A5FA 4NWFA 3WSHA 2HNPA 3NL5A 2QBRA 1WYEA 4JKSA 3RU3A 2CJZA 2VEUA 3HYOA 2JGVA 2B49A 3GXHA 4E8YA 4E75A 3D1OA 2F6ZA 5K9VA 3UAGA 5F11A 4QUMA 1JF7A 4GWFA 3KZHA 2IOJA 3QCIA 4LBXA 4KYRA 2RBCA 4C5JA 2QBQA 4RDDA 4RHGA 1U26A 3NCAA 3WSFA 2NTAA 4CVKA 3RPHA 2DXPA 2RF6A 1VK4A 2JFHA 3NC2A 2CNIA 3V0IA 4EN4A 1YWFA 1V1SA 1Q1MA 5IBSA 1RKSA 1V1BA 4KAHA 1G1FA 1GG4A 1BZCA 4B8SA 1RFUA 2PA5A 3QKPA 4QBWA 2B4SA 5KA9A 1G4WR 3MBJA 4LC4A 1WRMA 2I75A 3RTAA 1BZJA 2CMAA 4WTYA 4NYHA 3QCCA 3KEUA 2OZ5A 4OHDA 3I80A 3BF5A 1L2LA 2VTDA 4XCKA 4WU3A 1LQFA 5K9WA 3IH0A 1G7GA 2A8BA 3ZM2A 3O4TA 1RFVA 3DZVA 2YYBA 1YPTA 3QCHA 2HQQA 3MBHA 2HVLA 3V0FA 4CVLA 2F6VA 3V0EA 2ZMMA 3RQ8A 4HJQA 3NBWA 3N2AA 1LYVA 3RSFA 1XBOA 2CMBA 5KA2A 2Q5RA 3PYZA 1L8GA 4X8FA 3O4UA 1O5ZA 2QEPA 4O1GA 1YTNA 3N1CA 1WAXA 2C7SA 2AM1A 1XM2A 3D42A 2NLKA 1DGMA 4RH9A 1PH0A 4UBEA 1PXHA 2H4KA 1T49A 2DDWA 1C88A 1LIIA 4BUBA 2F6FA 3NL3A 3I36A 2AZRA 2Y96A 2H02A 2OOQA 3B1OA 3ZM5A 3LK7A 1KAKA 4JJPA 3U96A 3F41A 1YTSA 2Y68A 4K8TA 1P3DA 1E8CA 4K8CA 4KYQA 2GCAA 4S1IB 1D5RA 2F46A 5HDEA 2GC6A 5EYNA 4K9CA 3RREA 2J17A 2AJPA 3BLUA 1E0DA 3RQ6A 4OHIA 2VEXA 4HV4A 1GQYA 2F02A 3S3EA 4E3AA 3RO4A 5KADA 3HICA 4D3PA 4R0TA 3ZV2A 3RQXA 3HPDA 5K24A 4EOHA 1X24A 2FJMA 4WOHA 1BX4A 3VAQA 2ABQA 3QA2A
chains in the Genus database with same CATH topology
2Y68A 4IHFA 4E75A 3PYZA 2WJPA 2Y1OA 1P3DA 1E8CA 3UAGA 3MVNA 2IU8A 4QDIA 1O5ZA 2VTEA 2GCAA 4UAGA 2UAGA 2GC5A 2GC6A 2IUAA 1J6UA 2VTDA 2AM1A 1EEHA 1E0DA 2X5OA 2Y67A 4ZIYA 1JBVA 2VOSA 4BUCA 3ZL8A 1GQQA 2JFGA 2UUPA 2GCBA 5A5EA 4CVKA 4HV4A 4CVMA 3PMOA 1W7KA 2JFHA 1GQYA 4IHGA 2F00A 2JFFA 3HN7A 2Y66A 1P31A 3ZM6A 3EH0A 4BUBA 4C13A 4IHHA 2XJAA 2IU9A 2AM2A 2VORA 4CVLA 1W78A 4QF5A 3QCZA 5A5FA 1GG4A 4C12A 2XPCA 3EAGA 4E79A 1UAGA 2WTZA 1JBWA 2UUOA 3ZM5A 3LK7A 1FGSA 3NRSA 3N2AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y68 A;  4IHF A;  4E75 A;  3PYZ A;  2WJP A;  2Y1O A;  1P3D A;  1E8C A;  3UAG A;  3MVN A;  2IU8 A;  4QDI A;  1O5Z A;  2VTE A;  2GCA A;  4UAG A;  2UAG A;  2GC5 A;  2GC6 A;  2IUA A;  1J6U A;  2VTD A;  2AM1 A;  1EEH A;  1E0D A;  2X5O A;  2Y67 A;  4ZIY A;  1JBV A;  2VOS A;  4BUC A;  3ZL8 A;  1GQQ A;  2JFG A;  2UUP A;  2GCB A;  5A5E A;  4CVK A;  4HV4 A;  4CVM A;  3PMO A;  1W7K A;  2JFH A;  1GQY A;  4IHG A;  2F00 A;  2JFF A;  3HN7 A;  2Y66 A;  1P31 A;  3ZM6 A;  3EH0 A;  4BUB A;  4C13 A;  4IHH A;  2XJA A;  2IU9 A;  2AM2 A;  2VOR A;  4CVL A;  1W78 A;  4QF5 A;  3QCZ A;  5A5F A;  1GG4 A;  4C12 A;  2XPC A;  3EAG A;  4E79 A;  1UAG A;  2WTZ A;  1JBW A;  2UUO A;  3ZM5 A;  3LK7 A;  1FGS A;  3NRS A;  3N2A A; 
#chains in the Genus database with same CATH topology
 3SR9 A;  1OEV A;  3ZMP A;  2Y1O A;  1LIK A;  4YWR A;  2VTE A;  1OES A;  1PYN A;  1Q6M A;  4DGP A;  1UB0 A;  1C84 A;  1JLN A;  4WU2 A;  4XF6 A;  1GC5 A;  1PTT A;  2IUA A;  1J6U A;  5EY7 A;  3RO1 A;  2PT0 A;  1UA4 A;  1FPZ A;  3QCB A;  4I8N A;  3V0J A;  2F7K A;  3UQD A;  5A5E A;  3RQQ A;  3RTG A;  5KA1 A;  4HRF A;  2R3E A;  1C87 A;  5COJ A;  3EMU A;  3OTX A;  2I6A A;  2XTB A;  5BYD A;  1V3A A;  2CNF A;  1KYH A;  1EKQ A;  3EAG A;  2AWD A;  3PS5 A;  4GE5 A;  4YAA A;  4IWM A;  1PA1 A;  2WJP A;  2CM8 A;  2PSZ A;  3WSI A;  4GE2 A;  3EU0 A;  3QCJ A;  4S1H A;  2ZN7 A;  4KAL A;  2A3K A;  3RRJ A;  4QBE A;  3ZMQ A;  2YXT A;  5EHR A;  3QCE A;  2I6O A;  3QCG A;  5BZX A;  4GRY A;  1ZCL A;  4ZIY A;  2B3O A;  2F6Y A;  3RQ5 A;  3B3L A;  1ECV A;  2GWO A;  3O4S A;  2F6W A;  4Y14 A;  5BUG A;  2Y66 A;  3LJS A;  4R30 A;  4ZRT A;  2AM2 A;  3LKI A;  2DDO A;  2I6M A;  4NX8 A;  1PTV A;  3ZM1 A;  1W78 A;  3B1N A;  2BGE A;  3NC9 A;  4GS0 A;  2PKF A;  4QUN A;  2I4E A;  2H4G A;  3D9C A;  4IHF A;  3OLR A;  3GBU A;  5K22 A;  3B1Q A;  2I3R A;  2R0B A;  5KAB A;  2QHP A;  2FV7 A;  3A5J A;  1YGK A;  1T4J A;  4BPC A;  4C5L A;  4S1I A;  3NM3 A;  1Q6P A;  3CQD A;  1JXH A;  4YR8 B;  1XRI A;  5KA3 A;  3RTE A;  2QDC A;  1W7K A;  1V1A A;  2JFF A;  2I5B A;  1JXI A;  4ZN5 A;  2AHS A;  3IKH A;  3CM3 A;  3MOZ A;  2YDU A;  3RT7 A;  4E8W A;  4N09 A;  1EEO A;  2QBP A;  4JMK A;  5I6V A;  3RS8 A;  2V78 A;  2NV5 A;  1XXP A;  1A5Y A;  4XF7 A;  4WJM A;  1VM7 A;  2Q47 A;  5LXQ B;  4N08 A;  2BZL A;  4JBC A;  4DGX A;  4OHE A;  2VEY A;  2OC3 A;  4BJO A;  3BGK A;  1YGU A;  2ABS A;  3JUL A;  3RSG A;  2I6B A;  3L31 A;  1RK2 A;  1MKP A;  2NZ6 A;  1NMP A;  5CGA A;  2AFB A;  3LJ8 A;  3UMO A;  2X5O A;  3IN1 A;  2F70 A;  1JBV A;  5M43 A;  2HC2 A;  3PMO A;  2JFG A;  3UQE A;  2P6X A;  1WCH A;  1M3G A;  3MOW A;  4HJP A;  2GP0 A;  1GFY A;  4GM6 A;  3L2B A;  3B1P A;  2P4D A;  4IHH A;  3RGO A;  3QCM A;  2AX3 A;  3QCZ A;  1I9T A;  3QCL A;  4C12 A;  1ONZ A;  4MBB A;  4E79 A;  1C83 A;  2UUO A;  3H74 A;  2CMC A;  2I5X A;  4IKC A;  1C86 A;  4RI4 A;  1KNX A;  2CM3 A;  3M4U A;  1EKK A;  2PI7 A;  1LHR A;  3PL2 A;  2BIJ A;  1AAX A;  1TD2 A;  4K9I A;  2QDM A;  3V0G A;  5KA0 A;  1TZ3 A;  1RPM A;  1LIO A;  2C4E A;  1VI9 A;  2VEV A;  4E84 A;  3UQ9 A;  4RI5 A;  1QZ0 A;  2F00 A;  4O1L A;  2F6T A;  1I9S A;  1RKA A;  4R0S A;  3K5W A;  3QCD A;  1TZ6 A;  2PKN A;  3BRH A;  5EHP A;  5J8R A;  3F9B A;  4RH5 A;  3ZM0 A;  4D3Q A;  3LOO A;  1C85 A;  3IE7 A;  2AA0 A;  4RKK A;  2VEW A;  4C5M A;  4U7X A;  4UAG A;  3GO7 A;  3RS9 A;  2HNQ A;  5TQI A;  4EBU A;  2YXU A;  1FPR A;  4ERC A;  1OHE A;  3QKQ A;  2IMG A;  2QDP A;  4K8K A;  4ICZ A;  2UUP A;  1Q6J A;  4JNB A;  4JMJ A;  2CM7 A;  1OHD A;  5KA8 A;  5K25 A;  2B07 A;  3RSS A;  1G4U S;  2NT7 A;  4OHL A;  3WSG A;  1J4X A;  3D44 A;  3D1Q A;  1YHJ A;  2I4G A;  2MBC A;  3EZZ A;  2A9Z A;  1NL9 A;  4B04 A;  3PZS A;  2WTZ A;  1JBW A;  2VAR A;  1I57 A;  3UBO A;  5K23 A;  1G1G A;  1C3Q A;  3RSQ A;  4GFV A;  2PKK A;  4J51 A;  3S4E A;  3Q1Y A;  4NND A;  1GWZ A;  4S1M A;  5MMZ B;  1VHR A;  3ZS7 A;  3BLT A;  1OHC A;  2CNH A;  2QBS A;  4BUC A;  2CM2 A;  2B4U A;  3RQ2 A;  1GQQ A;  4KBE A;  3RQH A;  4GRZ A;  3UQ6 A;  2G59 A;  4KAD A;  3HN7 A;  2J16 A;  1PTU A;  4C13 A;  2IU9 A;  1U25 A;  5TRW A;  3FHY A;  4C5K A;  2VOR A;  4QF5 A;  2HLZ A;  4E69 A;  1QXK A;  1YN9 A;  3F9A A;  2NWH A;  5C40 A;  3CWE A;  3RTD A;  5BYE A;  4IWG A;  4D3R A;  3LHX A;  3NL6 A;  2GJT A;  3O3L A;  1Q6T A;  4QAH A;  1FQ1 A;  1ONY A;  2HXP A;  2I6P A;  3AWG A;  1PTY A;  3NME A;  2DDM A;  4IHG A;  4CVM A;  2G6Z A;  1YZ4 A;  4YL5 A;  3H2X A;  2FH7 A;  5BX1 A;  3FHX A;  3N0A A;  3RRB A;  2Q05 A;  1L8K A;  3F81 A;  2AB8 A;  5BYC A;  1OEO X;  1NWL A;  3QCN A;  2SHP A;  2WGP A;  1FGS A;  5KAC A;  1LAR A;  2HB1 A;  3RTC A;  3NL2 A;  4K93 A;  1R6H A;  2CNE A;  2QCJ A;  2QCV A;  3MVN A;  1EEN A;  3HJ6 A;  1G7F A;  4K8P A;  3RGQ A;  2HY3 A;  2DCN A;  1LHP A;  2I1Y A;  3KD6 A;  4KAN A;  2JG5 A;  5CGE A;  4GFU A;  3IBQ A;  2QCT A;  1ZZW A;  5KA7 A;  5GTJ A;  1OET A;  1YGJ A;  2Y67 A;  1NNY A;  4PVG A;  4H1O A;  5AWX A;  1T48 A;  1ZC0 A;  2I3U A;  1G1H A;  4DC3 A;  4GE6 A;  3NBV A;  2ESB A;  4PVV A;  1XXV A;  3IQ0 A;  4NWG A;  2C49 A;  4OHH A;  5C3Z A;  1RKD A;  3DRW A;  3KTN A;  5KAA A;  2E0T A;  5CM5 A;  2I4H A;  4DU5 A;  3H49 A;  5C41 A;  2CFV A;  3AWF A;  2PQ5 A;  2HCM A;  3GXG A;  4E8Z A;  4TVV A;  1OEM X;  3GO6 A;  2C46 A;  1KO7 A;  1PA9 A;  4H34 A;  1YTW A;  4KI9 A;  3A5K A;  2AJR A;  5IBM A;  1YGR A;  1NMO A;  3S3K A;  1ESQ A;  2H04 A;  2F71 A;  2VOS A;  3RPZ A;  2A9Y A;  2GCB A;  2Y2F A;  3BM8 A;  1YFO A;  3VAS A;  2H4V A;  2I6J A;  5KA4 A;  4EUM A;  3ZM6 A;  2JG1 A;  3AWE A;  3O5X A;  1BZH A;  1NO6 A;  3W4S A;  4Z6B A;  2OUD A;  2JJD A;  2XPC A;  2B4O A;  1UAG A;  3OMH A;  3ZL8 A;  2H03 A;  3I3Y A;  1NWE A;  4QAP A;  1ESJ A;  3EAX A;  4LBG A;  3F99 A;  5BZZ A;  2IU8 A;  4QDI A;  3RRF A;  3S4O A;  1RFT A;  4C5N A;  3V0H A;  1Q6S A;  2CNG A;  1KAV A;  2HC1 A;  3RY7 A;  3QCK A;  3I7Z A;  2FJN A;  3UMP A;  2BGD A;  1U2X A;  2NT2 A;  2R3B A;  4B8R A;  2PKM A;  5BYF A;  4PYH A;  3ZM3 A;  4S0G A;  1Q6N A;  3S3F A;  3Q92 A;  2XJA A;  1V19 A;  3V0D A;  2BV5 A;  3K9E A;  3RTB A;  3QAI A;  4LCA A;  3EB1 A;  1RXD A;  3RU2 A;  3NRS A;  3RM5 A;  2I42 A;  1GQT A;  1P15 A;  1TYY A;  2B4P A;  3SME A;  1U24 A;  2M3V A;  3EWM A;  4XDA A;  3WSE A;  2UAG A;  2GC5 A;  3B1R A;  5C3Y A;  1NZ7 A;  2I6I A;  2J16 B;  1OEU A;  1EEH A;  3RT9 A;  4JKU A;  5B6A A;  3NM1 A;  3WSD A;  4Y2E A;  3B7O A;  3EEQ A;  3D1H A;  1LIJ A;  2FYW A;  2HW1 A;  3MMJ A;  3QCF A;  3S3H A;  1ZCK A;  1P31 A;  2PBN A;  3EH0 A;  4ZI4 A;  5F0Z A;  4AZ1 A;  1SUG A;  3RZ2 A;  5A5F A;  4NWF A;  3WSH A;  2HNP A;  3NL5 A;  2QBR A;  1WYE A;  4JKS A;  3RU3 A;  2CJZ A;  2VEU A;  3HYO A;  2JGV A;  2B49 A;  3GXH A;  4E8Y A;  4E75 A;  3D1O A;  2F6Z A;  5K9V A;  3UAG A;  5F11 A;  4QUM A;  1JF7 A;  4GWF A;  3KZH A;  2IOJ A;  3QCI A;  4LBX A;  4KYR A;  2RBC A;  4C5J A;  2QBQ A;  4RDD A;  4RHG A;  1U26 A;  3NCA A;  3WSF A;  2NTA A;  4CVK A;  3RPH A;  2DXP A;  2RF6 A;  1VK4 A;  2JFH A;  3NC2 A;  2CNI A;  3V0I A;  4EN4 A;  1YWF A;  1V1S A;  1Q1M A;  5IBS A;  1RKS A;  1V1B A;  4KAH A;  1G1F A;  1GG4 A;  1BZC A;  4B8S A;  1RFU A;  2PA5 A;  3QKP A;  4QBW A;  2B4S A;  5KA9 A;  1G4W R;  3MBJ A;  4LC4 A;  1WRM A;  2I75 A;  3RTA A;  1BZJ A;  2CMA A;  4WTY A;  4NYH A;  3QCC A;  3KEU A;  2OZ5 A;  4OHD A;  3I80 A;  3BF5 A;  1L2L A;  2VTD A;  4XCK A;  4WU3 A;  1LQF A;  5K9W A;  3IH0 A;  1G7G A;  2A8B A;  3ZM2 A;  3O4T A;  1RFV A;  3DZV A;  2YYB A;  1YPT A;  3QCH A;  2HQQ A;  3MBH A;  2HVL A;  3V0F A;  4CVL A;  2F6V A;  3V0E A;  2ZMM A;  3RQ8 A;  4HJQ A;  3NBW A;  3N2A A;  1LYV A;  3RSF A;  1XBO A;  2CMB A;  5KA2 A;  2Q5R A;  3PYZ A;  1L8G A;  4X8F A;  3O4U A;  1O5Z A;  2QEP A;  4O1G A;  1YTN A;  3N1C A;  1WAX A;  2C7S A;  2AM1 A;  1XM2 A;  3D42 A;  2NLK A;  1DGM A;  4RH9 A;  1PH0 A;  4UBE A;  1PXH A;  2H4K A;  1T49 A;  2DDW A;  1C88 A;  1LII A;  4BUB A;  2F6F A;  3NL3 A;  3I36 A;  2AZR A;  2Y96 A;  2H02 A;  2OOQ A;  3B1O A;  3ZM5 A;  3LK7 A;  1KAK A;  4JJP A;  3U96 A;  3F41 A;  1YTS A;  2Y68 A;  4K8T A;  1P3D A;  1E8C A;  4K8C A;  4KYQ A;  2GCA A;  4S1I B;  1D5R A;  2F46 A;  5HDE A;  2GC6 A;  5EYN A;  4K9C A;  3RRE A;  2J17 A;  2AJP A;  3BLU A;  1E0D A;  3RQ6 A;  4OHI A;  2VEX A;  4HV4 A;  1GQY A;  2F02 A;  3S3E A;  4E3A A;  3RO4 A;  5KAD A;  3HIC A;  4D3P A;  4R0T A;  3ZV2 A;  3RQX A;  3HPD A;  5K24 A;  4EOH A;  1X24 A;  2FJM A;  4WOH A;  1BX4 A;  3VAQ A;  2ABQ A;  3QA2 A; 
#chains in the Genus database with same CATH homology
 2Y68 A;  4IHF A;  4E75 A;  3PYZ A;  2WJP A;  2Y1O A;  1P3D A;  1E8C A;  3UAG A;  3MVN A;  2IU8 A;  4QDI A;  1O5Z A;  2VTE A;  2GCA A;  4UAG A;  2UAG A;  2GC5 A;  2GC6 A;  2IUA A;  1J6U A;  2VTD A;  2AM1 A;  1EEH A;  1E0D A;  2X5O A;  2Y67 A;  4ZIY A;  1JBV A;  2VOS A;  4BUC A;  3ZL8 A;  1GQQ A;  2JFG A;  2UUP A;  2GCB A;  5A5E A;  4CVK A;  4HV4 A;  4CVM A;  3PMO A;  1W7K A;  2JFH A;  1GQY A;  4IHG A;  2F00 A;  2JFF A;  3HN7 A;  2Y66 A;  1P31 A;  3ZM6 A;  3EH0 A;  4BUB A;  4C13 A;  4IHH A;  2XJA A;  2IU9 A;  2AM2 A;  2VOR A;  4CVL A;  1W78 A;  4QF5 A;  3QCZ A;  5A5F A;  1GG4 A;  4C12 A;  2XPC A;  3EAG A;  4E79 A;  1UAG A;  2WTZ A;  1JBW A;  2UUO A;  3ZM5 A;  3LK7 A;  1FGS A;  3NRS A;  3N2A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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