3ZM6A

Crystal structure of murf ligase in complex with cyanothiophene inhibitor
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
454
structure length
454
Chain Sequence
MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Ligase
molecule keywords UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE
total genus 161
structure length 454
sequence length 454
ec nomenclature ec 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
pdb deposition date 2013-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01225 Mur_ligase Mur ligase family, catalytic domain
A PF02875 Mur_ligase_C Mur ligase family, glutamate ligase domain
A PF08245 Mur_ligase_M Mur ligase middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1190.10 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase Mur-like, catalytic domain 3zm6A02
3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 MurE/MurF, N-terminal domain 3zm6A01
3.90.190.20 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Mur ligase, C-terminal domain 3zm6A03
3NRSA 3ZM5A 2UAGA 2VTEA 2XPCA 1P3DA 2Y1OA 2JFHA 4UAGA 4CVKA 4IHFA 2GCBA 1E0DA 3LK7A 4BUBA 2Y66A 2AM1A 1W78A 1W7KA 5A5FA 2Y68A 2WTZA 3N2AA 1GQQA 4C12A 1FGSA 2GCAA 3UAGA 1JBVA 2AM2A 3ZM6A 1E8CA 1EEHA 4E79A 2VOSA 5A5EA 2IUAA 4C13A 1O5ZA 2X5OA 2VORA 4E75A 3QCZA 4BUCA 3MVNA 4ZIYA 2IU9A 2VTDA 4IHHA 3ZL8A 2IU8A 1UAGA 3HN7A 2GC5A 4QF5A 3PMOA 2XJAA 2UUPA 3PYZA 3EAGA 4CVMA 1GG4A 2JFGA 4QDIA 2WJPA 2UUOA 2JFFA 1P31A 3EH0A 4IHGA 2Y67A 4CVLA 1GQYA 1J6UA 1JBWA 2F00A 4HV4A 2GC6A
chains in the Genus database with same CATH superfamily
5GTJA 2AJPA 1G4US 4BPCA 1Q1MA 1U24A 3ZMPA 4XF6A 3RQQA 4QAHA 1LIOA 2H02A 2I42A 3RSFA 4C5LA 1OHCA 2I6OA 3RO4A 5IBSA 2PI7A 2DDOA 2GP0A 2NWHA 4O1LA 3ZMQA 5KAAA 2GWOA 3AWFA 2HNQA 2VTDA 1Q6PA 3NL5A 4KALA 4S1HA 3HICA 1YPTA 4LBXA 3S3KA 3FHYA 3WSHA 1LQFA 3F9AA 1G4WR 3QKQA 5LXQB 3QKPA 2I3UA 3S3FA 3QCKA 1YGKA 1JBWA 4K9CA 2HXPA 1JF7A 3OTXA 4UAGA 2FV7A 4YR8B 3UQDA 5K24A 2F6TA 2NT7A 3NBVA 2MBCA 5CGEA 4C12A 5KA0A 3UAGA 1OEUA 3O4TA 3QCGA 4JMJA 3RTAA 3SMEA 3RPZA 1VHRA 1U2XA 1YTSA 1RKDA 4YWRA 2HVLA 3UBOA 2AWDA 1T49A 1Q6NA 1PA9A 2P4DA 2B4OA 1LHPA 4ICZA 3HYOA 1FPZA 4GRZA 4KANA 4IHHA 3ZL8A 1G7FA 1LHRA 3LKIA 3WSIA 5K22A 2QBPA 1YWFA 3QCNA 4K8PA 1PYNA 3D44A 2UAGA 2CNHA 2JFHA 1G1FA 3QCBA 2F7KA 2CMCA 3NMEA 2I4GA 2VEYA 2RF6A 1ESQA 4JMKA 3RQ8A 2ABSA 3MOWA 3RQ2A 2BGDA 1FPRA 2C46A 1EEHA 1GQTA 2NTAA 2X5OA 3V0GA 3I7ZA 3QCJA 2YYBA 2DDWA 3QCFA 1AAXA 2QEPA 1UAGA 4QF5A 2ESBA 2I6AA 3SR9A 3H49A 1KAKA 2I6PA 3BGKA 3A5KA 2I3RA 2I1YA 2CJZA 1BZHA 2F00A 3GBUA 3QAIA 2BV5A 1WYEA 3QCLA 2XPCA 3EEQA 1NWLA 2PT0A 1TZ6A 4IHFA 2QDCA 1YHJA 2GCBA 3RREA 4IWGA 4KYQA 1U25A 2PKMA 1VK4A 1ZCKA 2PBNA 3FHXA 2HLZA 4HRFA 2A3KA 2R0BA 1ZCLA 2FYWA 3WSFA 1KAVA 3MBHA 1O5ZA 3ZM2A 4DGPA 1R6HA 1A5YA 2B4UA 3B3LA 3QCHA 3PZSA 2GC5A 2PSZA 4JNBA 2CNGA 1Q6JA 3RSSA 2I5XA 3KZHA 3UQ6A 4K8TA 2CM2A 2JFFA 4GE2A 1GQYA 1GFYA 1YTNA 4OHEA 4K8CA 1C83A 1P3DA 1XXPA 2I4HA 2AJRA 5KA9A 4KAHA 5KA4A 1QZ0A 5F0ZA 4GE5A 2I4EA 1BZCA 4NNDA 5BZXA 1V1SA 2R3BA 2JGVA 1EKQA 4LC4A 4GS0A 2IUAA 3V0DA 2AA0A 2VEUA 2FH7A 4KI9A 1ZC0A 1PXHA 3BF5A 5K9WA 1ESJA 3HN7A 2Q47A 1RKSA 3RQXA 2VEWA 3V0JA 5K9VA 3D1OA 1XM2A 3Q92A 5BYFA 3BLTA 2UUOA 2E0TA 4EOHA 5KA3A 1GWZA 3RS8A 3I80A 4Y2EA 1WRMA 4GE6A 2AB8A 3V0IA 3RZ2A 5C40A 5A5FA 2Y68A 2G6ZA 4DC3A 3WSDA 3L31A 3MMJA 1TD2A 3RM5A 3ZM6A 2I75A 3IKHA 3O3LA 5CM5A 3S3HA 2BGEA 1JLNA 5A5EA 5AWXA 3UMPA 4C13A 3B1QA 1RK2A 3IBQA 3NCAA 2QBQA 4HJQA 4WU3A 4ZN5A 5IBMA 4U7XA 4C5JA 4R0TA 3RQHA 5EYNA 2CMAA 3RT9A 5BZZA 2HC1A 1V1BA 3ZV2A 2I6MA 1BX4A 4H1OA 3K5WA 1LIKA 1D5RA 1OHDA 3RQ6A 5C3YA 4D3RA 4B8RA 1OHEA 1NMOA 1W78A 3Q1YA 2VEVA 4IKCA 4B04A 1FGSA 3BM8A 5KACA 3N1CA 2NLKA 1OEVA 3N0AA 3RRJA 1L8KA 5KABA 2V78A 2PKNA 1I9TA 2H04A 3O4SA 1RFVA 1T48A 2ZN7A 4GFVA 1PH0A 1P15A 1PTYA 2NV5A 3RSQA 2I5BA 3RGOA 2BZLA 4CVMA 3EAGA 1SUGA 1UA4A 3AWGA 5TQIA 2VARA 3D42A 3PS5A 1RKAA 2QBRA 2HNPA 2F6YA 3NBWA 4ERCA 3S3EA 1VM7A 1QXKA 4S0GA 4E8WA 2WGPA 2OZ5A 4GRYA 2B4PA 4HJPA 2CM8A 3V0EA 2YXTA 1JBVA 2Y2FA 5I6VA 3IQ0A 3LOOA 2OC3A 3QCMA 4GFUA 2XTBA 4XCKA 2F46A 2SHPA 3QCZA 3RU2A 3RTDA 1NWEA 2IU8A 5K25A 2QCVA 2XJAA 2F6FA 3VASA 2I6JA 1PTUA 2DCNA 2PA5A 4E8YA 3RGQA 4OHHA 1G1HA 1ONYA 3RTEA 1OESA 2QDMA 4D3QA 4MBBA 4CVKA 1NO6A 2AX3A 3S4OA 4RHGA 1LIIA 2F6ZA 1VI9A 1DGMA 2FJNA 2I6BA 3B1OA 2A9ZA 2VOSA 1ONZA 4LCAA 1OETA 1TZ3A 3KEUA 2QCJA 3QCCA 4Z6BA 4E75A 2DDMA 5C3ZA 3MVNA 3RRBA 4S1IB 2J16B 4C5KA 3WSGA 5BX1A 1XRIA 2NT2A 2HCMA 2F70A 3RQ5A 1GG4A 3NM1A 3DRWA 2WJPA 3KTNA 4IHGA 3UQ9A 1X24A 3B7OA 2G59A 1J6UA 1UB0A 3LHXA 4OHLA 4I8NA 4WTYA 4K93A 5KA7A 4EN4A 1I9SA 3HPDA 1YFOA 3LK7A 4C5NA 3IH0A 2WTZA 3N2AA 5BUGA 5COJA 2GCAA 4NX8A 3HJ6A 1E8CA 1C86A 2Y96A 3B1NA 3LJSA 4NWFA 4PVGA 4B8SA 2A8BA 4BJOA 2OOQA 3KD6A 5BYEA 4WOHA 3B1RA 1NNYA 5KADA 4JKSA 1XXVA 2C4EA 2P6XA 1G1GA 3AWEA 3RS9A 4HV4A 3NM3A 2OUDA 2VEXA 2HY3A 2Y1OA 3EWMA 5HDEA 1U26A 4H34A 1RFUA 1ECVA 1W7KA 2FJMA 3OMHA 4C5MA 1XBOA 3D1QA 3S4EA 4DGXA 4QBWA 4QUNA 1ZZWA 3F99A 3MOZA 3UMOA 3O4UA 5CGAA 4S1IA 1YTWA 2J16A 1NMPA 3JULA 1YGUA 3GO7A 4OHDA 5EY7A 4N08A 2YDUA 4WU2A 3EZZA 2CNEA 4R30A 4WJMA 3V0FA 3EAXA 2IMGA 1RXDA 3O5XA 3QCEA 2IOJA 2B07A 4LBGA 4DU5A 4O1GA 4E3AA 2CFVA 2F02A 4RKKA 5KA2A 4GM6A 4UBEA 1C85A 1PA1A 4YAAA 2Y66A 1J4XA 2B3OA 2NZ6A 3LJ8A 2F6VA 1EENA 3RTGA 4PYHA 3K9EA 5MMZB 2BIJA 4E79A 2B4SA 4RH9A 2H4VA 3F9BA 1Q6TA 3OLRA 1OEOX 4ZIYA 3NL6A 1FQ1A 1YGRA 4NYHA 4N09A 3V0HA 2B49A 2J17A 2UUPA 1YZ4A 2HW1A 2R3EA 2PKKA 3EH0A 4RI5A 1WAXA 2I6IA 3GXHA 1PTTA 1BZJA 2H4GA 4QAPA 5J8RA 1RPMA 3QCDA 3ZM0A 2HQQA 4E8ZA 5B6AA 2AZRA 1LIJA 2F71A 3H74A 3RO1A 3RU3A 2QDPA 3H2XA 4E84A 4JBCA 2JJDA 3RSGA 3I3YA 1EEOA 3F41A 3A5JA 3NC2A 4RI4A 5K23A 4KYRA 2DXPA 3BRHA 2Y67A 4CVLA 4KADA 5BYCA 1WCHA 1M3GA 3NRSA 1YGJA 4KBEA 2VTEA 5M43A 2JG1A 3EMUA 4ZI4A 2AM1A 3NC9A 1C84A 1G7GA 3IE7A 1JXHA 3MBJA 3WSEA 1C88A 3QCIA 1NL9A 3QA2A 4X8FA 1I57A 1L2LA 1T4JA 3RTBA 2QHPA 2A9YA 5BYDA 4EUMA 3ZM1A 1RFTA 3W4SA 4IWMA 2GJTA 2C49A 4XF7A 1EKKA 2QBSA 3D9CA 1GC5A 3VAQA 5C41A 3NL2A 5EHPA 3PYZA 3RRFA 3UQEA 4EBUA 4JJPA 3ZM3A 2HC2A 3IN1A 1PTVA 4K8KA 3CQDA 1KYHA 4ZRTA 1Q6SA 3F81A 1KNXA 4OHIA 4QUMA 1JXIA 1OEMX 2CM7A 1E0DA 2RBCA 3B1PA 4BUBA 2Q05A 4TVVA 4K9IA 2CNFA 1GQQA 4S1MA 4RDDA 2AM2A 3CM3A 1TYYA 5F11A 3DZVA 3M4UA 3NL3A 1V3AA 1L8GA 2F6WA 2PKFA 5KA8A 2H4KA 3RTCA 2Q5RA 2IU9A 2CNIA 1MKPA 3I36A 4D3PA 4Y14A 4J51A 2ABQA 1V19A 3RT7A 2JG5A 3GO6A 1LYVA 3RY7A 2AHSA 1P31A 3PMOA 3ZS7A 3GXGA 4RH5A 4R0SA 3ZM5A 3EU0A 4GWFA 4E69A 3CWEA 2CM3A 4AZ1A 5KA1A 3L2BA 3EB1A 3U96A 2AFBA 1NZ7A 2HB1A 4PVVA 2CMBA 4YL5A 4NWGA 1YN9A 2VORA 1C3QA 2ZMMA 4JKUA 1V1AA 1KO7A 4BUCA 2M3VA 3RPHA 3D1HA 4XDAA 3PL2A 5EHRA 2QCTA 2YXUA 3BLUA 1Q6MA 2PQ5A 2JFGA 4QDIA 5TRWA 1LARA 2H03A 4QBEA 1C87A 2C7SA 2GC6A
chains in the Genus database with same CATH topology
3NRSA 3ZM5A 2UAGA 2VTEA 2XPCA 1P3DA 2Y1OA 2JFHA 4UAGA 4CVKA 4IHFA 2GCBA 1E0DA 3LK7A 4BUBA 2Y66A 2AM1A 1W78A 1W7KA 5A5FA 2Y68A 2WTZA 3N2AA 1GQQA 4C12A 1FGSA 2GCAA 3UAGA 1JBVA 2AM2A 3ZM6A 1E8CA 1EEHA 4E79A 2VOSA 5A5EA 2IUAA 4C13A 1O5ZA 2X5OA 2VORA 4E75A 3QCZA 4BUCA 3MVNA 4ZIYA 2IU9A 2VTDA 4IHHA 3ZL8A 2IU8A 1UAGA 3HN7A 2GC5A 4QF5A 3PMOA 2XJAA 2UUPA 3PYZA 3EAGA 4CVMA 1GG4A 2JFGA 4QDIA 2WJPA 2UUOA 2JFFA 1P31A 3EH0A 4IHGA 2Y67A 4CVLA 1GQYA 1J6UA 1JBWA 2F00A 4HV4A 2GC6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NRS A;  3ZM5 A;  2UAG A;  2VTE A;  2XPC A;  1P3D A;  2Y1O A;  2JFH A;  4UAG A;  4CVK A;  4IHF A;  2GCB A;  1E0D A;  3LK7 A;  4BUB A;  2Y66 A;  2AM1 A;  1W78 A;  1W7K A;  5A5F A;  2Y68 A;  2WTZ A;  3N2A A;  1GQQ A;  4C12 A;  1FGS A;  2GCA A;  3UAG A;  1JBV A;  2AM2 A;  3ZM6 A;  1E8C A;  1EEH A;  4E79 A;  2VOS A;  5A5E A;  2IUA A;  4C13 A;  1O5Z A;  2X5O A;  2VOR A;  4E75 A;  3QCZ A;  4BUC A;  3MVN A;  4ZIY A;  2IU9 A;  2VTD A;  4IHH A;  3ZL8 A;  2IU8 A;  1UAG A;  3HN7 A;  2GC5 A;  4QF5 A;  3PMO A;  2XJA A;  2UUP A;  3PYZ A;  3EAG A;  4CVM A;  1GG4 A;  2JFG A;  4QDI A;  2WJP A;  2UUO A;  2JFF A;  1P31 A;  3EH0 A;  4IHG A;  2Y67 A;  4CVL A;  1GQY A;  1J6U A;  1JBW A;  2F00 A;  4HV4 A;  2GC6 A; 
#chains in the Genus database with same CATH topology
 5GTJ A;  2AJP A;  1G4U S;  4BPC A;  1Q1M A;  1U24 A;  3ZMP A;  4XF6 A;  3RQQ A;  4QAH A;  1LIO A;  2H02 A;  2I42 A;  3RSF A;  4C5L A;  1OHC A;  2I6O A;  3RO4 A;  5IBS A;  2PI7 A;  2DDO A;  2GP0 A;  2NWH A;  4O1L A;  3ZMQ A;  5KAA A;  2GWO A;  3AWF A;  2HNQ A;  2VTD A;  1Q6P A;  3NL5 A;  4KAL A;  4S1H A;  3HIC A;  1YPT A;  4LBX A;  3S3K A;  3FHY A;  3WSH A;  1LQF A;  3F9A A;  1G4W R;  3QKQ A;  5LXQ B;  3QKP A;  2I3U A;  3S3F A;  3QCK A;  1YGK A;  1JBW A;  4K9C A;  2HXP A;  1JF7 A;  3OTX A;  4UAG A;  2FV7 A;  4YR8 B;  3UQD A;  5K24 A;  2F6T A;  2NT7 A;  3NBV A;  2MBC A;  5CGE A;  4C12 A;  5KA0 A;  3UAG A;  1OEU A;  3O4T A;  3QCG A;  4JMJ A;  3RTA A;  3SME A;  3RPZ A;  1VHR A;  1U2X A;  1YTS A;  1RKD A;  4YWR A;  2HVL A;  3UBO A;  2AWD A;  1T49 A;  1Q6N A;  1PA9 A;  2P4D A;  2B4O A;  1LHP A;  4ICZ A;  3HYO A;  1FPZ A;  4GRZ A;  4KAN A;  4IHH A;  3ZL8 A;  1G7F A;  1LHR A;  3LKI A;  3WSI A;  5K22 A;  2QBP A;  1YWF A;  3QCN A;  4K8P A;  1PYN A;  3D44 A;  2UAG A;  2CNH A;  2JFH A;  1G1F A;  3QCB A;  2F7K A;  2CMC A;  3NME A;  2I4G A;  2VEY A;  2RF6 A;  1ESQ A;  4JMK A;  3RQ8 A;  2ABS A;  3MOW A;  3RQ2 A;  2BGD A;  1FPR A;  2C46 A;  1EEH A;  1GQT A;  2NTA A;  2X5O A;  3V0G A;  3I7Z A;  3QCJ A;  2YYB A;  2DDW A;  3QCF A;  1AAX A;  2QEP A;  1UAG A;  4QF5 A;  2ESB A;  2I6A A;  3SR9 A;  3H49 A;  1KAK A;  2I6P A;  3BGK A;  3A5K A;  2I3R A;  2I1Y A;  2CJZ A;  1BZH A;  2F00 A;  3GBU A;  3QAI A;  2BV5 A;  1WYE A;  3QCL A;  2XPC A;  3EEQ A;  1NWL A;  2PT0 A;  1TZ6 A;  4IHF A;  2QDC A;  1YHJ A;  2GCB A;  3RRE A;  4IWG A;  4KYQ A;  1U25 A;  2PKM A;  1VK4 A;  1ZCK A;  2PBN A;  3FHX A;  2HLZ A;  4HRF A;  2A3K A;  2R0B A;  1ZCL A;  2FYW A;  3WSF A;  1KAV A;  3MBH A;  1O5Z A;  3ZM2 A;  4DGP A;  1R6H A;  1A5Y A;  2B4U A;  3B3L A;  3QCH A;  3PZS A;  2GC5 A;  2PSZ A;  4JNB A;  2CNG A;  1Q6J A;  3RSS A;  2I5X A;  3KZH A;  3UQ6 A;  4K8T A;  2CM2 A;  2JFF A;  4GE2 A;  1GQY A;  1GFY A;  1YTN A;  4OHE A;  4K8C A;  1C83 A;  1P3D A;  1XXP A;  2I4H A;  2AJR A;  5KA9 A;  4KAH A;  5KA4 A;  1QZ0 A;  5F0Z A;  4GE5 A;  2I4E A;  1BZC A;  4NND A;  5BZX A;  1V1S A;  2R3B A;  2JGV A;  1EKQ A;  4LC4 A;  4GS0 A;  2IUA A;  3V0D A;  2AA0 A;  2VEU A;  2FH7 A;  4KI9 A;  1ZC0 A;  1PXH A;  3BF5 A;  5K9W A;  1ESJ A;  3HN7 A;  2Q47 A;  1RKS A;  3RQX A;  2VEW A;  3V0J A;  5K9V A;  3D1O A;  1XM2 A;  3Q92 A;  5BYF A;  3BLT A;  2UUO A;  2E0T A;  4EOH A;  5KA3 A;  1GWZ A;  3RS8 A;  3I80 A;  4Y2E A;  1WRM A;  4GE6 A;  2AB8 A;  3V0I A;  3RZ2 A;  5C40 A;  5A5F A;  2Y68 A;  2G6Z A;  4DC3 A;  3WSD A;  3L31 A;  3MMJ A;  1TD2 A;  3RM5 A;  3ZM6 A;  2I75 A;  3IKH A;  3O3L A;  5CM5 A;  3S3H A;  2BGE A;  1JLN A;  5A5E A;  5AWX A;  3UMP A;  4C13 A;  3B1Q A;  1RK2 A;  3IBQ A;  3NCA A;  2QBQ A;  4HJQ A;  4WU3 A;  4ZN5 A;  5IBM A;  4U7X A;  4C5J A;  4R0T A;  3RQH A;  5EYN A;  2CMA A;  3RT9 A;  5BZZ A;  2HC1 A;  1V1B A;  3ZV2 A;  2I6M A;  1BX4 A;  4H1O A;  3K5W A;  1LIK A;  1D5R A;  1OHD A;  3RQ6 A;  5C3Y A;  4D3R A;  4B8R A;  1OHE A;  1NMO A;  1W78 A;  3Q1Y A;  2VEV A;  4IKC A;  4B04 A;  1FGS A;  3BM8 A;  5KAC A;  3N1C A;  2NLK A;  1OEV A;  3N0A A;  3RRJ A;  1L8K A;  5KAB A;  2V78 A;  2PKN A;  1I9T A;  2H04 A;  3O4S A;  1RFV A;  1T48 A;  2ZN7 A;  4GFV A;  1PH0 A;  1P15 A;  1PTY A;  2NV5 A;  3RSQ A;  2I5B A;  3RGO A;  2BZL A;  4CVM A;  3EAG A;  1SUG A;  1UA4 A;  3AWG A;  5TQI A;  2VAR A;  3D42 A;  3PS5 A;  1RKA A;  2QBR A;  2HNP A;  2F6Y A;  3NBW A;  4ERC A;  3S3E A;  1VM7 A;  1QXK A;  4S0G A;  4E8W A;  2WGP A;  2OZ5 A;  4GRY A;  2B4P A;  4HJP A;  2CM8 A;  3V0E A;  2YXT A;  1JBV A;  2Y2F A;  5I6V A;  3IQ0 A;  3LOO A;  2OC3 A;  3QCM A;  4GFU A;  2XTB A;  4XCK A;  2F46 A;  2SHP A;  3QCZ A;  3RU2 A;  3RTD A;  1NWE A;  2IU8 A;  5K25 A;  2QCV A;  2XJA A;  2F6F A;  3VAS A;  2I6J A;  1PTU A;  2DCN A;  2PA5 A;  4E8Y A;  3RGQ A;  4OHH A;  1G1H A;  1ONY A;  3RTE A;  1OES A;  2QDM A;  4D3Q A;  4MBB A;  4CVK A;  1NO6 A;  2AX3 A;  3S4O A;  4RHG A;  1LII A;  2F6Z A;  1VI9 A;  1DGM A;  2FJN A;  2I6B A;  3B1O A;  2A9Z A;  2VOS A;  1ONZ A;  4LCA A;  1OET A;  1TZ3 A;  3KEU A;  2QCJ A;  3QCC A;  4Z6B A;  4E75 A;  2DDM A;  5C3Z A;  3MVN A;  3RRB A;  4S1I B;  2J16 B;  4C5K A;  3WSG A;  5BX1 A;  1XRI A;  2NT2 A;  2HCM A;  2F70 A;  3RQ5 A;  1GG4 A;  3NM1 A;  3DRW A;  2WJP A;  3KTN A;  4IHG A;  3UQ9 A;  1X24 A;  3B7O A;  2G59 A;  1J6U A;  1UB0 A;  3LHX A;  4OHL A;  4I8N A;  4WTY A;  4K93 A;  5KA7 A;  4EN4 A;  1I9S A;  3HPD A;  1YFO A;  3LK7 A;  4C5N A;  3IH0 A;  2WTZ A;  3N2A A;  5BUG A;  5COJ A;  2GCA A;  4NX8 A;  3HJ6 A;  1E8C A;  1C86 A;  2Y96 A;  3B1N A;  3LJS A;  4NWF A;  4PVG A;  4B8S A;  2A8B A;  4BJO A;  2OOQ A;  3KD6 A;  5BYE A;  4WOH A;  3B1R A;  1NNY A;  5KAD A;  4JKS A;  1XXV A;  2C4E A;  2P6X A;  1G1G A;  3AWE A;  3RS9 A;  4HV4 A;  3NM3 A;  2OUD A;  2VEX A;  2HY3 A;  2Y1O A;  3EWM A;  5HDE A;  1U26 A;  4H34 A;  1RFU A;  1ECV A;  1W7K A;  2FJM A;  3OMH A;  4C5M A;  1XBO A;  3D1Q A;  3S4E A;  4DGX A;  4QBW A;  4QUN A;  1ZZW A;  3F99 A;  3MOZ A;  3UMO A;  3O4U A;  5CGA A;  4S1I A;  1YTW A;  2J16 A;  1NMP A;  3JUL A;  1YGU A;  3GO7 A;  4OHD A;  5EY7 A;  4N08 A;  2YDU A;  4WU2 A;  3EZZ A;  2CNE A;  4R30 A;  4WJM A;  3V0F A;  3EAX A;  2IMG A;  1RXD A;  3O5X A;  3QCE A;  2IOJ A;  2B07 A;  4LBG A;  4DU5 A;  4O1G A;  4E3A A;  2CFV A;  2F02 A;  4RKK A;  5KA2 A;  4GM6 A;  4UBE A;  1C85 A;  1PA1 A;  4YAA A;  2Y66 A;  1J4X A;  2B3O A;  2NZ6 A;  3LJ8 A;  2F6V A;  1EEN A;  3RTG A;  4PYH A;  3K9E A;  5MMZ B;  2BIJ A;  4E79 A;  2B4S A;  4RH9 A;  2H4V A;  3F9B A;  1Q6T A;  3OLR A;  1OEO X;  4ZIY A;  3NL6 A;  1FQ1 A;  1YGR A;  4NYH A;  4N09 A;  3V0H A;  2B49 A;  2J17 A;  2UUP A;  1YZ4 A;  2HW1 A;  2R3E A;  2PKK A;  3EH0 A;  4RI5 A;  1WAX A;  2I6I A;  3GXH A;  1PTT A;  1BZJ A;  2H4G A;  4QAP A;  5J8R A;  1RPM A;  3QCD A;  3ZM0 A;  2HQQ A;  4E8Z A;  5B6A A;  2AZR A;  1LIJ A;  2F71 A;  3H74 A;  3RO1 A;  3RU3 A;  2QDP A;  3H2X A;  4E84 A;  4JBC A;  2JJD A;  3RSG A;  3I3Y A;  1EEO A;  3F41 A;  3A5J A;  3NC2 A;  4RI4 A;  5K23 A;  4KYR A;  2DXP A;  3BRH A;  2Y67 A;  4CVL A;  4KAD A;  5BYC A;  1WCH A;  1M3G A;  3NRS A;  1YGJ A;  4KBE A;  2VTE A;  5M43 A;  2JG1 A;  3EMU A;  4ZI4 A;  2AM1 A;  3NC9 A;  1C84 A;  1G7G A;  3IE7 A;  1JXH A;  3MBJ A;  3WSE A;  1C88 A;  3QCI A;  1NL9 A;  3QA2 A;  4X8F A;  1I57 A;  1L2L A;  1T4J A;  3RTB A;  2QHP A;  2A9Y A;  5BYD A;  4EUM A;  3ZM1 A;  1RFT A;  3W4S A;  4IWM A;  2GJT A;  2C49 A;  4XF7 A;  1EKK A;  2QBS A;  3D9C A;  1GC5 A;  3VAQ A;  5C41 A;  3NL2 A;  5EHP A;  3PYZ A;  3RRF A;  3UQE A;  4EBU A;  4JJP A;  3ZM3 A;  2HC2 A;  3IN1 A;  1PTV A;  4K8K A;  3CQD A;  1KYH A;  4ZRT A;  1Q6S A;  3F81 A;  1KNX A;  4OHI A;  4QUM A;  1JXI A;  1OEM X;  2CM7 A;  1E0D A;  2RBC A;  3B1P A;  4BUB A;  2Q05 A;  4TVV A;  4K9I A;  2CNF A;  1GQQ A;  4S1M A;  4RDD A;  2AM2 A;  3CM3 A;  1TYY A;  5F11 A;  3DZV A;  3M4U A;  3NL3 A;  1V3A A;  1L8G A;  2F6W A;  2PKF A;  5KA8 A;  2H4K A;  3RTC A;  2Q5R A;  2IU9 A;  2CNI A;  1MKP A;  3I36 A;  4D3P A;  4Y14 A;  4J51 A;  2ABQ A;  1V19 A;  3RT7 A;  2JG5 A;  3GO6 A;  1LYV A;  3RY7 A;  2AHS A;  1P31 A;  3PMO A;  3ZS7 A;  3GXG A;  4RH5 A;  4R0S A;  3ZM5 A;  3EU0 A;  4GWF A;  4E69 A;  3CWE A;  2CM3 A;  4AZ1 A;  5KA1 A;  3L2B A;  3EB1 A;  3U96 A;  2AFB A;  1NZ7 A;  2HB1 A;  4PVV A;  2CMB A;  4YL5 A;  4NWG A;  1YN9 A;  2VOR A;  1C3Q A;  2ZMM A;  4JKU A;  1V1A A;  1KO7 A;  4BUC A;  2M3V A;  3RPH A;  3D1H A;  4XDA A;  3PL2 A;  5EHR A;  2QCT A;  2YXU A;  3BLU A;  1Q6M A;  2PQ5 A;  2JFG A;  4QDI A;  5TRW A;  1LAR A;  2H03 A;  4QBE A;  1C87 A;  2C7S A;  2GC6 A; 
#chains in the Genus database with same CATH homology
 3NRS A;  3ZM5 A;  2UAG A;  2VTE A;  2XPC A;  1P3D A;  2Y1O A;  2JFH A;  4UAG A;  4CVK A;  4IHF A;  2GCB A;  1E0D A;  3LK7 A;  4BUB A;  2Y66 A;  2AM1 A;  1W78 A;  1W7K A;  5A5F A;  2Y68 A;  2WTZ A;  3N2A A;  1GQQ A;  4C12 A;  1FGS A;  2GCA A;  3UAG A;  1JBV A;  2AM2 A;  3ZM6 A;  1E8C A;  1EEH A;  4E79 A;  2VOS A;  5A5E A;  2IUA A;  4C13 A;  1O5Z A;  2X5O A;  2VOR A;  4E75 A;  3QCZ A;  4BUC A;  3MVN A;  4ZIY A;  2IU9 A;  2VTD A;  4IHH A;  3ZL8 A;  2IU8 A;  1UAG A;  3HN7 A;  2GC5 A;  4QF5 A;  3PMO A;  2XJA A;  2UUP A;  3PYZ A;  3EAG A;  4CVM A;  1GG4 A;  2JFG A;  4QDI A;  2WJP A;  2UUO A;  2JFF A;  1P31 A;  3EH0 A;  4IHG A;  2Y67 A;  4CVL A;  1GQY A;  1J6U A;  1JBW A;  2F00 A;  4HV4 A;  2GC6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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