3ZM6A

Crystal structure of murf ligase in complex with cyanothiophene inhibitor
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
454
structure length
454
Chain Sequence
MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf.
pubmed doi rcsb
molecule tags Ligase
source organism Streptococcus pneumoniae
molecule keywords UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE
total genus 161
structure length 454
sequence length 454
ec nomenclature ec 6.3.2.10: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
pdb deposition date 2013-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01225 Mur_ligase Mur ligase family, catalytic domain
A PF02875 Mur_ligase_C Mur ligase family, glutamate ligase domain
A PF08245 Mur_ligase_M Mur ligase middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1190.10 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase Mur-like, catalytic domain 3zm6A02
3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 MurE/MurF, N-terminal domain 3zm6A01
3.90.190.20 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Mur ligase, C-terminal domain 3zm6A03
2UUOA 3ZM6A 1P31A 2WJPA 2VTEA 2GC6A 4IHGA 1J6UA 2UUPA 1FGSA 4HV4A 1GQQA 4UAGA 3PMOA 2VTDA 3ZM5A 3EAGA 2GC5A 5A5EA 3LK7A 4C13A 1P3DA 2GCBA 1JBWA 2JFFA 3PYZA 1E8CA 2VORA 4CVMA 4BUBA 4CVLA 2JFGA 5A5FA 2JFHA 4E79A 2IU8A 1JBVA 2Y1OA 1E0DA 3HN7A 2XPCA 4ZIYA 1W7KA 3N2AA 1O5ZA 4IHHA 2VOSA 1GQYA 2X5OA 2AM1A 3ZL8A 4QDIA 2IU9A 2IUAA 3MVNA 4QF5A 1EEHA 2F00A 1GG4A 1UAGA 2XJAA 4IHFA 3NRSA 4BUCA 1W78A 2UAGA 4C12A 3QCZA 2AM2A 2Y67A 4E75A 2GCAA 4CVKA 3EH0A 3UAGA 2WTZA 2Y68A 2Y66A
chains in the Genus database with same CATH superfamily
2QBSA 4UBEA 3F81A 4JMKA 1XXVA 3D9CA 3NL5A 4D3QA 1P31A 3WSHA 4IHGA 4K8KA 3BLUA 4KI9A 3HYOA 4IWGA 2G6ZA 2P6XA 1OHEA 3D1HA 2PI7A 1PTVA 3BLTA 3MMJA 5IBMA 2DXPA 3KEUA 2Q05A 3RU3A 4HV4A 4UAGA 4GS0A 2VTDA 3EU0A 2CM8A 4YWRA 2H02A 1RK2A 3NM3A 2CMBA 4GM6A 2VEYA 4C13A 4GRYA 5EHRA 4B8RA 4EN4A 2GCBA 2PQ5A 3PYZA 3RO4A 2P4DA 1D5RA 1LIKA 5BYFA 3QKQA 3I80A 3D44A 4KANA 3RY7A 4HRFA 2CNFA 3BF5A 4CVMA 1ZCKA 4BUBA 2HNQA 1XXPA 3QCDA 4O1LA 2DDWA 5TQIA 3AWGA 4ZN5A 4E8WA 3UQ9A 2I3RA 2HW1A 4S1IB 5BYCA 5KA0A 3RT7A 2J16A 2JGVA 1RFUA 1WAXA 5TRWA 2CM7A 2DCNA 3HICA 4K8PA 3EZZA 3JULA 2QDCA 2BGEA 3RRBA 5I6VA 1JF7A 4JJPA 3K5WA 1TD2A 2BGDA 4K8CA 1LHRA 1JXIA 3RTDA 5BYEA 1FQ1A 1VI9A 3RREA 3Q92A 1DGMA 3N2AA 3UQEA 1TZ3A 2F46A 4C5JA 1O5ZA 1MKPA 2GWOA 5COJA 2J17A 4B8SA 2QBRA 1PTTA 3RTBA 4JKUA 2HVLA 2HB1A 1ECVA 3RTEA 1GQTA 2HC2A 3H2XA 5MMZB 1LIJA 3IKHA 2H04A 3NL6A 2C46A 4IKCA 3ZL8A 1TZ6A 2B49A 2AA0A 2C4EA 4QDIA 4DC3A 2IU9A 1V1SA 4KYQA 2I5XA 3QCLA 3GXGA 4KYRA 3S3EA 5K9VA 4YL5A 3WSDA 1G4WR 4QAPA 4RH5A 1KO7A 3V0JA 4OHDA 1NWEA 3N1CA 4S1HA 2Q47A 4ICZA 1RFTA 3MBHA 1GG4A 1UAGA 4X8FA 2I1YA 3LJ8A 4HJQA 4ZRTA 3QCCA 4D3RA 3UQ6A 2I4GA 1C86A 4EUMA 1G4US 2QCVA 1OHCA 2I5BA 1GWZA 2PSZA 1YGUA 2CJZA 1G7GA 4K9IA 3EEQA 3NBVA 4Y2EA 3NC9A 3QCZA 1PH0A 3EMUA 2AM2A 2HQQA 4U7XA 2F7KA 1GFYA 2GCAA 3KD6A 3V0HA 3D1OA 4CVKA 4QUMA 3S3KA 2QHPA 2GP0A 3NL2A 1FPRA 5EHPA 1NMOA 4JNBA 2WTZA 3SMEA 3V0EA 2Y68A 2PKNA 1I57A 2Y96A 2R0BA 1C84A 1NL9A 3B7OA 3RSSA 3RTCA 1U26A 3K9EA 2IMGA 1T4JA 1XRIA 4NYHA 2VARA 3UBOA 2QCTA 4NWGA 1YZ4A 2GC6A 5B6AA 1Q6NA 1J6UA 1NWLA 4Y14A 2F6WA 3DRWA 3BRHA 1LIIA 1YHJA 5KA8A 1YTSA 3RQ6A 1YGRA 3ZV2A 1VM7A 4QUNA 3RQ5A 2AWDA 3LK7A 2HNPA 1KNXA 5KA3A 1JBWA 2CM3A 1E8CA 4GFVA 5KADA 4R0SA 2YDUA 4EOHA 2I4HA 2NTAA 3RGQA 3FHXA 4E69A 4CVLA 3ZM2A 5K24A 4GRZA 1C88A 4H1OA 3S4OA 1UA4A 3OLRA 4AZ1A 4OHIA 4C5MA 1OEOX 4DGXA 3LOOA 3F99A 4N09A 2IU8A 4S0GA 5BZZA 3PS5A 3D1QA 2ESBA 2CNEA 4E8YA 5F0ZA 2I42A 3QCFA 2AJPA 4C5LA 2A3KA 3ZM3A 3L2BA 2XPCA 4ZIYA 3NL3A 4BJOA 4GWFA 5BZXA 4WJMA 5EY7A 5BYDA 4LBXA 3CM3A 4BPCA 4C5KA 2NT7A 5KABA 2OC3A 2NV5A 2VEUA 3GO6A 1JLNA 2NWHA 2R3BA 1BX4A 1RPMA 1GQYA 2X5OA 1LYVA 1ESJA 3WSEA 1KAKA 2AJRA 1YGKA 1Q1MA 3F9BA 2AM1A 5M43A 4KAHA 2HXPA 2OOQA 1ESQA 2MBCA 3AWFA 2IOJA 3QCGA 2NZ6A 2F70A 1EKKA 3RS9A 3I7ZA 3S3FA 5K25A 4S1IA 4O1GA 1EKQA 3NMEA 3IE7A 2HY3A 2XJAA 1BZHA 2G59A 1LHPA 2PKFA 4IHFA 3F41A 4GE2A 4BUCA 4WU2A 5BUGA 5BX1A 4KADA 4EBUA 2B4UA 2UAGA 4E3AA 2CNGA 3B1QA 2OUDA 3QCIA 1VHRA 4JBCA 4QBWA 3GO7A 2WGPA 2RF6A 2H4KA 2E0TA 1FPZA 3HPDA 4KBEA 1G1FA 3RSGA 2Y66A 2UUOA 1X24A 4N08A 2I6BA 3OTXA 3I3YA 1BZJA 3ZMQA 4JKSA 2VEVA 3H49A 2VTEA 4WU3A 3RPHA 2QBQA 3KTNA 3QCHA 2UUPA 1Q6SA 2ZMMA 2PA5A 1GQQA 3B1OA 2CMCA 2I6IA 4GE6A 3ZM5A 3S4EA 3EAGA 3O4UA 2GC5A 3ZS7A 1RFVA 5C3YA 4RKKA 3UMPA 1G1GA 5F11A 2FJNA 1UB0A 1L8KA 1NO6A 2VORA 2F6VA 2R3EA 2FH7A 2BIJA 1QZ0A 3MOWA 4J51A 4TVVA 3RQ2A 4IWMA 3A5JA 1V1AA 2YXUA 2YYBA 1YFOA 2JJDA 4H34A 2Q5RA 4GE5A 2JFGA 5A5FA 2AZRA 2DDMA 1PTUA 3O4SA 2I6PA 2BV5A 4RH9A 3RQQA 4ERCA 2CM2A 2AX3A 2QDPA 1JBVA 1LQFA 1XM2A 1WCHA 2I6MA 1V1BA 2QEPA 2Y1OA 4LCAA 2NLKA 1E0DA 5C3ZA 2YXTA 3HN7A 1WYEA 3QCMA 2HLZA 5CGEA 5GTJA 3RT9A 3IBQA 1YWFA 5HDEA 2B07A 3B3LA 3B1RA 2H4GA 1J4XA 3QAIA 5KA1A 2DDOA 3RU2A 1ONZA 1PA1A 5KA2A 1V19A 3RPZA 1QXKA 2PBNA 5AWXA 2JG5A 4QAHA 2QCJA 1NNYA 1RKDA 3NM1A 2B4OA 2CFVA 1KYHA 4E84A 2B4PA 2F6TA 2ZN7A 2C7SA 1RXDA 4RHGA 3RSFA 1V3AA 1LIOA 4I8NA 3WSGA 3MBJA 3UQDA 3RTGA 3RM5A 5J8RA 2AFBA 4LC4A 3RRFA 2A9YA 2HCMA 3RSQA 2ABSA 2IUAA 4PVGA 4PYHA 3ZMPA 2H4VA 1PA9A 2B4SA 4QF5A 5K9WA 2F00A 1KAVA 1Q6JA 3U96A 2NT2A 1U25A 1YN9A 3LHXA 2F6ZA 3GXHA 4WOHA 2VEWA 5EYNA 3FHYA 2A9ZA 2AB8A 1C3QA 4K8TA 1OHDA 4C12A 3I36A 3IQ0A 3O4TA 3OMHA 3EWMA 1OETA 5K23A 2I6JA 1T49A 2Y67A 2GJTA 4XF6A 5C41A 4LBGA 4E75A 1L8GA 4Z6BA 2J16B 1M3GA 2I6AA 3M4UA 3PL2A 2F71A 3UAGA 4NNDA 3RO1A 4XDAA 1JXHA 3RQXA 3O5XA 5C40A 3QCEA 2M3VA 4NWFA 4KALA 1L2LA 3A5KA 5KACA 1OESA 4MBBA 1LARA 5LXQB 3RGOA 3ZM6A 1YGJA 2WJPA 1ONYA 3IN1A 3NC2A 3EB1A 1C83A 5K22A 5KA7A 3RQ8A 1YTWA 2I6OA 3VAQA 4RI4A 3CWEA 1R6HA 3NCAA 2PT0A 1FGSA 2JG1A 4K9CA 2F6YA 1RKSA 3QA2A 4GFUA 3PMOA 2RBCA 5A5EA 1C87A 4PVVA 2QDMA 3L31A 1P3DA 4S1MA 2XTBA 2JFFA 2V78A 2CMAA 3D42A 1A5YA 2BZLA 1ZCLA 1WRMA 2H03A 3O3LA 1PXHA 4DGPA 1Q6MA 3V0DA 3H74A 2A8BA 2FJMA 5KA4A 1ZC0A 3BGKA 2OZ5A 4NX8A 2Y2FA 3RRJA 3CQDA 1PYNA 1NMPA 1G1HA 4OHEA 2VEXA 2JFHA 2PKKA 1OEMX 5IBSA 3WSIA 4E79A 3GBUA 4WTYA 3WSFA 1I9SA 1C85A 1OEUA 4R0TA 4XCKA 2QBPA 4RDDA 4D3PA 1Q6PA 3QCNA 1OEVA 3B1NA 1BZCA 5KAAA 4C5NA 3RZ2A 3W4SA 2ABQA 3V0IA 3QKPA 1W7KA 1G7FA 3F9AA 3B1PA 5CM5A 3RS8A 2I4EA 5CGAA 4OHLA 2F02A 4IHHA 1GC5A 3HJ6A 1SUGA 2VOSA 3SR9A 3BM8A 1P15A 1TYYA 3NBWA 1XBOA 3RTAA 3MOZA 4RI5A 4QBEA 2F6FA 1U24A 2I3UA 3Q1YA 2B3OA 4OHHA 3VASA 5KA9A 4R30A 1YPTA 2CNHA 2CNIA 4HJPA 1RKAA 2FV7A 1ZZWA 4B04A 2C49A 3MVNA 4YR8B 4DU5A 2HC1A 1EEHA 3DZVA 3QCJA 1I9TA 3QCKA 4YAAA 1U2XA 3EAXA 3LKIA 4ZI4A 3ZM1A 3V0FA 2SHPA 3KZHA 3NRSA 1AAXA 1W78A 4K93A 3AWEA 3S3HA 1EEOA 2I75A 3V0GA 1Q6TA 2PKMA 3LJSA 3PZSA 3N0AA 4JMJA 1NZ7A 1PTYA 1EENA 3QCBA 1YTNA 1T48A 4E8ZA 2AHSA 3EH0A 4XF7A 1VK4A 3UMOA 3ZM0A 2FYWA 3RQHA 3IH0A
chains in the Genus database with same CATH topology
2UUOA 3ZM6A 1P31A 2WJPA 2VTEA 2GC6A 4IHGA 1J6UA 2UUPA 1FGSA 4HV4A 1GQQA 4UAGA 3PMOA 2VTDA 3ZM5A 3EAGA 2GC5A 5A5EA 3LK7A 4C13A 1P3DA 2GCBA 1JBWA 2JFFA 3PYZA 1E8CA 2VORA 4CVMA 4BUBA 4CVLA 2JFGA 5A5FA 2JFHA 4E79A 2IU8A 1JBVA 2Y1OA 1E0DA 3HN7A 2XPCA 4ZIYA 1W7KA 3N2AA 1O5ZA 4IHHA 2VOSA 1GQYA 2X5OA 2AM1A 3ZL8A 4QDIA 2IU9A 2IUAA 3MVNA 4QF5A 1EEHA 2F00A 1GG4A 1UAGA 2XJAA 4IHFA 3NRSA 4BUCA 1W78A 2UAGA 4C12A 3QCZA 2AM2A 2Y67A 4E75A 2GCAA 4CVKA 3EH0A 3UAGA 2WTZA 2Y68A 2Y66A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UUO A;  3ZM6 A;  1P31 A;  2WJP A;  2VTE A;  2GC6 A;  4IHG A;  1J6U A;  2UUP A;  1FGS A;  4HV4 A;  1GQQ A;  4UAG A;  3PMO A;  2VTD A;  3ZM5 A;  3EAG A;  2GC5 A;  5A5E A;  3LK7 A;  4C13 A;  1P3D A;  2GCB A;  1JBW A;  2JFF A;  3PYZ A;  1E8C A;  2VOR A;  4CVM A;  4BUB A;  4CVL A;  2JFG A;  5A5F A;  2JFH A;  4E79 A;  2IU8 A;  1JBV A;  2Y1O A;  1E0D A;  3HN7 A;  2XPC A;  4ZIY A;  1W7K A;  3N2A A;  1O5Z A;  4IHH A;  2VOS A;  1GQY A;  2X5O A;  2AM1 A;  3ZL8 A;  4QDI A;  2IU9 A;  2IUA A;  3MVN A;  4QF5 A;  1EEH A;  2F00 A;  1GG4 A;  1UAG A;  2XJA A;  4IHF A;  3NRS A;  4BUC A;  1W78 A;  2UAG A;  4C12 A;  3QCZ A;  2AM2 A;  2Y67 A;  4E75 A;  2GCA A;  4CVK A;  3EH0 A;  3UAG A;  2WTZ A;  2Y68 A;  2Y66 A; 
#chains in the Genus database with same CATH topology
 2QBS A;  4UBE A;  3F81 A;  4JMK A;  1XXV A;  3D9C A;  3NL5 A;  4D3Q A;  1P31 A;  3WSH A;  4IHG A;  4K8K A;  3BLU A;  4KI9 A;  3HYO A;  4IWG A;  2G6Z A;  2P6X A;  1OHE A;  3D1H A;  2PI7 A;  1PTV A;  3BLT A;  3MMJ A;  5IBM A;  2DXP A;  3KEU A;  2Q05 A;  3RU3 A;  4HV4 A;  4UAG A;  4GS0 A;  2VTD A;  3EU0 A;  2CM8 A;  4YWR A;  2H02 A;  1RK2 A;  3NM3 A;  2CMB A;  4GM6 A;  2VEY A;  4C13 A;  4GRY A;  5EHR A;  4B8R A;  4EN4 A;  2GCB A;  2PQ5 A;  3PYZ A;  3RO4 A;  2P4D A;  1D5R A;  1LIK A;  5BYF A;  3QKQ A;  3I80 A;  3D44 A;  4KAN A;  3RY7 A;  4HRF A;  2CNF A;  3BF5 A;  4CVM A;  1ZCK A;  4BUB A;  2HNQ A;  1XXP A;  3QCD A;  4O1L A;  2DDW A;  5TQI A;  3AWG A;  4ZN5 A;  4E8W A;  3UQ9 A;  2I3R A;  2HW1 A;  4S1I B;  5BYC A;  5KA0 A;  3RT7 A;  2J16 A;  2JGV A;  1RFU A;  1WAX A;  5TRW A;  2CM7 A;  2DCN A;  3HIC A;  4K8P A;  3EZZ A;  3JUL A;  2QDC A;  2BGE A;  3RRB A;  5I6V A;  1JF7 A;  4JJP A;  3K5W A;  1TD2 A;  2BGD A;  4K8C A;  1LHR A;  1JXI A;  3RTD A;  5BYE A;  1FQ1 A;  1VI9 A;  3RRE A;  3Q92 A;  1DGM A;  3N2A A;  3UQE A;  1TZ3 A;  2F46 A;  4C5J A;  1O5Z A;  1MKP A;  2GWO A;  5COJ A;  2J17 A;  4B8S A;  2QBR A;  1PTT A;  3RTB A;  4JKU A;  2HVL A;  2HB1 A;  1ECV A;  3RTE A;  1GQT A;  2HC2 A;  3H2X A;  5MMZ B;  1LIJ A;  3IKH A;  2H04 A;  3NL6 A;  2C46 A;  4IKC A;  3ZL8 A;  1TZ6 A;  2B49 A;  2AA0 A;  2C4E A;  4QDI A;  4DC3 A;  2IU9 A;  1V1S A;  4KYQ A;  2I5X A;  3QCL A;  3GXG A;  4KYR A;  3S3E A;  5K9V A;  4YL5 A;  3WSD A;  1G4W R;  4QAP A;  4RH5 A;  1KO7 A;  3V0J A;  4OHD A;  1NWE A;  3N1C A;  4S1H A;  2Q47 A;  4ICZ A;  1RFT A;  3MBH A;  1GG4 A;  1UAG A;  4X8F A;  2I1Y A;  3LJ8 A;  4HJQ A;  4ZRT A;  3QCC A;  4D3R A;  3UQ6 A;  2I4G A;  1C86 A;  4EUM A;  1G4U S;  2QCV A;  1OHC A;  2I5B A;  1GWZ A;  2PSZ A;  1YGU A;  2CJZ A;  1G7G A;  4K9I A;  3EEQ A;  3NBV A;  4Y2E A;  3NC9 A;  3QCZ A;  1PH0 A;  3EMU A;  2AM2 A;  2HQQ A;  4U7X A;  2F7K A;  1GFY A;  2GCA A;  3KD6 A;  3V0H A;  3D1O A;  4CVK A;  4QUM A;  3S3K A;  2QHP A;  2GP0 A;  3NL2 A;  1FPR A;  5EHP A;  1NMO A;  4JNB A;  2WTZ A;  3SME A;  3V0E A;  2Y68 A;  2PKN A;  1I57 A;  2Y96 A;  2R0B A;  1C84 A;  1NL9 A;  3B7O A;  3RSS A;  3RTC A;  1U26 A;  3K9E A;  2IMG A;  1T4J A;  1XRI A;  4NYH A;  2VAR A;  3UBO A;  2QCT A;  4NWG A;  1YZ4 A;  2GC6 A;  5B6A A;  1Q6N A;  1J6U A;  1NWL A;  4Y14 A;  2F6W A;  3DRW A;  3BRH A;  1LII A;  1YHJ A;  5KA8 A;  1YTS A;  3RQ6 A;  1YGR A;  3ZV2 A;  1VM7 A;  4QUN A;  3RQ5 A;  2AWD A;  3LK7 A;  2HNP A;  1KNX A;  5KA3 A;  1JBW A;  2CM3 A;  1E8C A;  4GFV A;  5KAD A;  4R0S A;  2YDU A;  4EOH A;  2I4H A;  2NTA A;  3RGQ A;  3FHX A;  4E69 A;  4CVL A;  3ZM2 A;  5K24 A;  4GRZ A;  1C88 A;  4H1O A;  3S4O A;  1UA4 A;  3OLR A;  4AZ1 A;  4OHI A;  4C5M A;  1OEO X;  4DGX A;  3LOO A;  3F99 A;  4N09 A;  2IU8 A;  4S0G A;  5BZZ A;  3PS5 A;  3D1Q A;  2ESB A;  2CNE A;  4E8Y A;  5F0Z A;  2I42 A;  3QCF A;  2AJP A;  4C5L A;  2A3K A;  3ZM3 A;  3L2B A;  2XPC A;  4ZIY A;  3NL3 A;  4BJO A;  4GWF A;  5BZX A;  4WJM A;  5EY7 A;  5BYD A;  4LBX A;  3CM3 A;  4BPC A;  4C5K A;  2NT7 A;  5KAB A;  2OC3 A;  2NV5 A;  2VEU A;  3GO6 A;  1JLN A;  2NWH A;  2R3B A;  1BX4 A;  1RPM A;  1GQY A;  2X5O A;  1LYV A;  1ESJ A;  3WSE A;  1KAK A;  2AJR A;  1YGK A;  1Q1M A;  3F9B A;  2AM1 A;  5M43 A;  4KAH A;  2HXP A;  2OOQ A;  1ESQ A;  2MBC A;  3AWF A;  2IOJ A;  3QCG A;  2NZ6 A;  2F70 A;  1EKK A;  3RS9 A;  3I7Z A;  3S3F A;  5K25 A;  4S1I A;  4O1G A;  1EKQ A;  3NME A;  3IE7 A;  2HY3 A;  2XJA A;  1BZH A;  2G59 A;  1LHP A;  2PKF A;  4IHF A;  3F41 A;  4GE2 A;  4BUC A;  4WU2 A;  5BUG A;  5BX1 A;  4KAD A;  4EBU A;  2B4U A;  2UAG A;  4E3A A;  2CNG A;  3B1Q A;  2OUD A;  3QCI A;  1VHR A;  4JBC A;  4QBW A;  3GO7 A;  2WGP A;  2RF6 A;  2H4K A;  2E0T A;  1FPZ A;  3HPD A;  4KBE A;  1G1F A;  3RSG A;  2Y66 A;  2UUO A;  1X24 A;  4N08 A;  2I6B A;  3OTX A;  3I3Y A;  1BZJ A;  3ZMQ A;  4JKS A;  2VEV A;  3H49 A;  2VTE A;  4WU3 A;  3RPH A;  2QBQ A;  3KTN A;  3QCH A;  2UUP A;  1Q6S A;  2ZMM A;  2PA5 A;  1GQQ A;  3B1O A;  2CMC A;  2I6I A;  4GE6 A;  3ZM5 A;  3S4E A;  3EAG A;  3O4U A;  2GC5 A;  3ZS7 A;  1RFV A;  5C3Y A;  4RKK A;  3UMP A;  1G1G A;  5F11 A;  2FJN A;  1UB0 A;  1L8K A;  1NO6 A;  2VOR A;  2F6V A;  2R3E A;  2FH7 A;  2BIJ A;  1QZ0 A;  3MOW A;  4J51 A;  4TVV A;  3RQ2 A;  4IWM A;  3A5J A;  1V1A A;  2YXU A;  2YYB A;  1YFO A;  2JJD A;  4H34 A;  2Q5R A;  4GE5 A;  2JFG A;  5A5F A;  2AZR A;  2DDM A;  1PTU A;  3O4S A;  2I6P A;  2BV5 A;  4RH9 A;  3RQQ A;  4ERC A;  2CM2 A;  2AX3 A;  2QDP A;  1JBV A;  1LQF A;  1XM2 A;  1WCH A;  2I6M A;  1V1B A;  2QEP A;  2Y1O A;  4LCA A;  2NLK A;  1E0D A;  5C3Z A;  2YXT A;  3HN7 A;  1WYE A;  3QCM A;  2HLZ A;  5CGE A;  5GTJ A;  3RT9 A;  3IBQ A;  1YWF A;  5HDE A;  2B07 A;  3B3L A;  3B1R A;  2H4G A;  1J4X A;  3QAI A;  5KA1 A;  2DDO A;  3RU2 A;  1ONZ A;  1PA1 A;  5KA2 A;  1V19 A;  3RPZ A;  1QXK A;  2PBN A;  5AWX A;  2JG5 A;  4QAH A;  2QCJ A;  1NNY A;  1RKD A;  3NM1 A;  2B4O A;  2CFV A;  1KYH A;  4E84 A;  2B4P A;  2F6T A;  2ZN7 A;  2C7S A;  1RXD A;  4RHG A;  3RSF A;  1V3A A;  1LIO A;  4I8N A;  3WSG A;  3MBJ A;  3UQD A;  3RTG A;  3RM5 A;  5J8R A;  2AFB A;  4LC4 A;  3RRF A;  2A9Y A;  2HCM A;  3RSQ A;  2ABS A;  2IUA A;  4PVG A;  4PYH A;  3ZMP A;  2H4V A;  1PA9 A;  2B4S A;  4QF5 A;  5K9W A;  2F00 A;  1KAV A;  1Q6J A;  3U96 A;  2NT2 A;  1U25 A;  1YN9 A;  3LHX A;  2F6Z A;  3GXH A;  4WOH A;  2VEW A;  5EYN A;  3FHY A;  2A9Z A;  2AB8 A;  1C3Q A;  4K8T A;  1OHD A;  4C12 A;  3I36 A;  3IQ0 A;  3O4T A;  3OMH A;  3EWM A;  1OET A;  5K23 A;  2I6J A;  1T49 A;  2Y67 A;  2GJT A;  4XF6 A;  5C41 A;  4LBG A;  4E75 A;  1L8G A;  4Z6B A;  2J16 B;  1M3G A;  2I6A A;  3M4U A;  3PL2 A;  2F71 A;  3UAG A;  4NND A;  3RO1 A;  4XDA A;  1JXH A;  3RQX A;  3O5X A;  5C40 A;  3QCE A;  2M3V A;  4NWF A;  4KAL A;  1L2L A;  3A5K A;  5KAC A;  1OES A;  4MBB A;  1LAR A;  5LXQ B;  3RGO A;  3ZM6 A;  1YGJ A;  2WJP A;  1ONY A;  3IN1 A;  3NC2 A;  3EB1 A;  1C83 A;  5K22 A;  5KA7 A;  3RQ8 A;  1YTW A;  2I6O A;  3VAQ A;  4RI4 A;  3CWE A;  1R6H A;  3NCA A;  2PT0 A;  1FGS A;  2JG1 A;  4K9C A;  2F6Y A;  1RKS A;  3QA2 A;  4GFU A;  3PMO A;  2RBC A;  5A5E A;  1C87 A;  4PVV A;  2QDM A;  3L31 A;  1P3D A;  4S1M A;  2XTB A;  2JFF A;  2V78 A;  2CMA A;  3D42 A;  1A5Y A;  2BZL A;  1ZCL A;  1WRM A;  2H03 A;  3O3L A;  1PXH A;  4DGP A;  1Q6M A;  3V0D A;  3H74 A;  2A8B A;  2FJM A;  5KA4 A;  1ZC0 A;  3BGK A;  2OZ5 A;  4NX8 A;  2Y2F A;  3RRJ A;  3CQD A;  1PYN A;  1NMP A;  1G1H A;  4OHE A;  2VEX A;  2JFH A;  2PKK A;  1OEM X;  5IBS A;  3WSI A;  4E79 A;  3GBU A;  4WTY A;  3WSF A;  1I9S A;  1C85 A;  1OEU A;  4R0T A;  4XCK A;  2QBP A;  4RDD A;  4D3P A;  1Q6P A;  3QCN A;  1OEV A;  3B1N A;  1BZC A;  5KAA A;  4C5N A;  3RZ2 A;  3W4S A;  2ABQ A;  3V0I A;  3QKP A;  1W7K A;  1G7F A;  3F9A A;  3B1P A;  5CM5 A;  3RS8 A;  2I4E A;  5CGA A;  4OHL A;  2F02 A;  4IHH A;  1GC5 A;  3HJ6 A;  1SUG A;  2VOS A;  3SR9 A;  3BM8 A;  1P15 A;  1TYY A;  3NBW A;  1XBO A;  3RTA A;  3MOZ A;  4RI5 A;  4QBE A;  2F6F A;  1U24 A;  2I3U A;  3Q1Y A;  2B3O A;  4OHH A;  3VAS A;  5KA9 A;  4R30 A;  1YPT A;  2CNH A;  2CNI A;  4HJP A;  1RKA A;  2FV7 A;  1ZZW A;  4B04 A;  2C49 A;  3MVN A;  4YR8 B;  4DU5 A;  2HC1 A;  1EEH A;  3DZV A;  3QCJ A;  1I9T A;  3QCK A;  4YAA A;  1U2X A;  3EAX A;  3LKI A;  4ZI4 A;  3ZM1 A;  3V0F A;  2SHP A;  3KZH A;  3NRS A;  1AAX A;  1W78 A;  4K93 A;  3AWE A;  3S3H A;  1EEO A;  2I75 A;  3V0G A;  1Q6T A;  2PKM A;  3LJS A;  3PZS A;  3N0A A;  4JMJ A;  1NZ7 A;  1PTY A;  1EEN A;  3QCB A;  1YTN A;  1T48 A;  4E8Z A;  2AHS A;  3EH0 A;  4XF7 A;  1VK4 A;  3UMO A;  3ZM0 A;  2FYW A;  3RQH A;  3IH0 A; 
#chains in the Genus database with same CATH homology
 2UUO A;  3ZM6 A;  1P31 A;  2WJP A;  2VTE A;  2GC6 A;  4IHG A;  1J6U A;  2UUP A;  1FGS A;  4HV4 A;  1GQQ A;  4UAG A;  3PMO A;  2VTD A;  3ZM5 A;  3EAG A;  2GC5 A;  5A5E A;  3LK7 A;  4C13 A;  1P3D A;  2GCB A;  1JBW A;  2JFF A;  3PYZ A;  1E8C A;  2VOR A;  4CVM A;  4BUB A;  4CVL A;  2JFG A;  5A5F A;  2JFH A;  4E79 A;  2IU8 A;  1JBV A;  2Y1O A;  1E0D A;  3HN7 A;  2XPC A;  4ZIY A;  1W7K A;  3N2A A;  1O5Z A;  4IHH A;  2VOS A;  1GQY A;  2X5O A;  2AM1 A;  3ZL8 A;  4QDI A;  2IU9 A;  2IUA A;  3MVN A;  4QF5 A;  1EEH A;  2F00 A;  1GG4 A;  1UAG A;  2XJA A;  4IHF A;  3NRS A;  4BUC A;  1W78 A;  2UAG A;  4C12 A;  3QCZ A;  2AM2 A;  2Y67 A;  4E75 A;  2GCA A;  4CVK A;  3EH0 A;  3UAG A;  2WTZ A;  2Y68 A;  2Y66 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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