3A73A

Crystal structure analysis of human serum albumin complexed with delta 12-prostaglandin j2
Total Genus 222
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
222
sequence length
583
structure length
576
Chain Sequence
AHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146.
pubmed doi rcsb
molecule tags Lipid binding protein
molecule keywords Serum albumin
total genus 222
structure length 576
sequence length 583
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-09-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3a73A05
2I30A 4OT2A 1E7HA 2BXFA 4L9KA 5IIHA 3TDLA 2XVUA 4J2VA 2BXPA 3B9LA 1GNJA 4LB2A 1E7BA 5ID7A 2BXCA 2YDFA 1BM0A 2I2ZA 2VDBA 5IFOA 1AO6A 1J78A 3LU6A 3JQZA 3V09A 1H9ZA 4BKEA 1HK3A 2BXMA 4K2CA 3V03A 5FUOA 2BXBA 3UIVA 4F5VA 5DBYA 4IW1A 4Z69A 4LB9A 2BXIA 1HK5A 4LA0A 3CX9A 2BXLA 4ZBQA 1HA2A 2BXDA 3LU7A 1E7IA 3V08A 4K71A 4N0FD 2XVQA 1N5UA 5DQFA 4S1YA 1E7EA 1KXPD 1HK2A 4N0UD 3JRYA 3LU8A 5IIXA 2BXAA 2BXNA 2BXOA 1E7CA 1UORA 1E7GA 4F5TA 1BJ5A 1HK4A 4E99A 3SQJA 2XW1A 1GNIA 5IIUA 4F5UA 1BKEA 1J7EA 2BXEA 4ZBRA 4LUFA 3A73A 4JK4A 2XVVA 1LOTA 2BXHA 4G04A 4HGKA 1O9XA 4G03A 5IJFA 5HOZA 4LUHA 1HK1A 5ID9A 5IJ5A 2BXKA 4L8UA 1E7FA 2XVWA 2XSIA 4L9QA 4EMXA 4HGMB 2BX8A 1E7AA 2VUFA 1MA9A 4OR0A 5GHKA 2VUEA 1TF0A 3B9MA 2BXGA 2XW0A 4IW2A 1E78A 5IJEA 4F5SA 2BXQA 1KW2A 4PO0A
chains in the Genus database with same CATH superfamily
5GIPA 2DYMA 1JNBA 2I30A 4OT2A 2KWFA 2Z8JA 2DBXA 3WHQA 3NVMA 1E7HA 3NVKA 2BXFA 4L9KA 1IJGA 3TDLA 5IIHA 2XVUA 4J2VA 2BXPA 3B9LA 4ZC6A 5GINA 1GNJA 2OT3A 3BPJA 1MIYA 1MIVA 4LB2A 1E7BA 2JUHA 5ID7A 4C31B 3NMUA 1MUHA 3FWBC 2BXCA 2YDFA 1LNSA 1BM0A 2I2ZA 1FOUA 2VDBA 3GA9L 5IFOA 1AO6A 4GDKB 3W1SA 1J78A 4NAWB 2DG5A 2NQOA 2V36A 2Z8IA 2AJEA 2E0YA 3LU6A 2EFCA 3JQZA 1MUSA 3V09A 1H9ZA 4BKEA 4FIPB 2EFEA 2NNWA 1HK3A 3GQUA 4ZBKA 2BXMA 2LQIA 4K2CA 3V03A 5FUOA 2BXBA 2GUTA 3UIVA 4F5VA 5DBYA 3GQXA 4IW1A 4Z69A 3H37A 4LB9A 2BXIA 1HK5A 4LA0A 2DBUA 3M99C 1NT2B 2BXLA 3CX9A 4ZBQA 4DHXB 3FNMA 1HA2A 3MHHB 2QHBA 3G9KD 4TQ1A 2BXDA 3LU7A 5B5TA 1E7IA 1KDXA 3ICXA 4GG2A 2E0XA 4GDLB 3KJLA 4DM0A 2Z8KA 3MHSB 3V08A 4K71A 4N0FD 2XVQA 1N5UA 1H5WA 2LQHA 4Z9OA 5DQFA 4S1YA 1E7EA 4TQ0A 1KXPD 2EFHA 1HK2A 4N3ZA 3KIKA 3WHRA 4N0UD 3JRYA 2LOQA 2QM6A 4I9OA 3LU8A 5D7GA 5IIXA 2BXAA 2BXNA 2BXOA 1VFIA 1E7CA 1UORA 4GDXA 1E7GA 4FJCB 4F5TA 1BJ5A 1HK4A 3ECPA 3SIVB 2QMCA 4E99A 4W4UB 3SQJA 2XW1A 2DYOA 1GNIA 1VZSA 2CKXA 5IIUA 5GIOA 4F5UA 2OZBB 1MM8A 1BKEA 1J7EA 2BXEA 4BY9C 1SB0A 4ZBRA 4LUFA 3A73A 4JK4A 2XVVA 1LOTA 2BXHA 4G04A 4MBEC 4OTTA 2LXTA 4M70B 4OTUA 5BPKA 4D7XA 4HGKA 3PLAA 3SIUB 4FK5B 1O9XA 4G03A 1MIWA 5IJFA 4G01A 5HOZA 4LUHA 1HK1A 5ID9A 5IJ5A 2BXKA 2LXSA 4L8UA 1E7FA 3VQIA 3WHSA 2XVWA 2XMOA 2XSIA 3FWCC 4L9QA 2K0NA 2DBWA 2EFDA 2ROHA 3A75A 3H3AA 4EMXA 4WA6B 3NVIA 4HGMB 2BX8A 1E7AA 2VUFA 1MA9A 4OR0A 5GHKA 2VUEA 4F5SA 4ZUXV 1TF0A 3B9MA 2BXGA 2XW0A 4IW2A 1E78A 5IJEA 4ZCGA 2KBZA 1TXUA 2BXQA 1KW2A 2AGHB 4PO0A
chains in the Genus database with same CATH topology
5GIPA 2DYMA 1JNBA 2I30A 4OT2A 2Z8JA 2DBXA 3NVMA 1E7HA 2BXFA 4L9KA 1IJGA 3TDLA 5IIHA 2XVUA 4J2VA 2BXPA 3B9LA 4ZC6A 5GINA 1GNJA 2OT3A 1MIYA 1MIVA 4LB2A 2JUHA 1E7BA 5ID7A 4C31B 3NMUA 3FWBC 2BXCA 2YDFA 1LNSA 1BM0A 2I2ZA 1FOUA 2VDBA 3GA9L 5IFOA 1AO6A 4GDKB 3W1SA 1J78A 4NAWB 2DG5A 2NQOA 2V36A 2Z8IA 2AJEA 2E0YA 3LU6A 2EFCA 3JQZA 3V09A 1H9ZA 4BKEA 4FIPB 2EFEA 2NNWA 1HK3A 3GQUA 4ZBKA 2BXMA 4K2CA 3V03A 5FUOA 2BXBA 3UIVA 4F5VA 5DBYA 3GQXA 4IW1A 4Z69A 3H37A 4LB9A 2BXIA 1HK5A 4LA0A 2DBUA 3M99C 1NT2B 2BXLA 3CX9A 4ZBQA 4DHXB 3FNMA 1HA2A 3MHHB 2QHBA 3G9KD 4TQ1A 2BXDA 3LU7A 5B5TA 1E7IA 3ICXA 4GG2A 2E0XA 4GDLB 3KJLA 2Z8KA 3MHSB 3V08A 4K71A 4N0FD 2XVQA 1N5UA 1H5WA 4Z9OA 5DQFA 3WHQA 4S1YA 1E7EA 4TQ0A 1KXPD 2EFHA 1HK2A 4N3ZA 3KIKA 3WHRA 4N0UD 3JRYA 2LOQA 2QM6A 3LU8A 5D7GA 5IIXA 2BXAA 2BXNA 2BXOA 1VFIA 1E7CA 1UORA 4GDXA 1E7GA 4FJCB 4F5TA 1BJ5A 1HK4A 3SIVB 2QMCA 4E99A 4W4UB 3SQJA 2XW1A 2DYOA 1GNIA 1VZSA 2CKXA 5IIUA 5GIOA 4F5UA 2OZBB 1BKEA 1J7EA 2BXEA 4BY9C 4ZBRA 4LUFA 3A73A 4JK4A 2XVVA 1LOTA 2BXHA 4G04A 4MBEC 4OTTA 4OTUA 4M70B 5BPKA 3NVKA 3PLAA 4HGKA 3SIUB 1O9XA 4G03A 1MIWA 5IJFA 4G01A 5HOZA 4LUHA 1HK1A 5ID9A 5IJ5A 2BXKA 4L8UA 1E7FA 3VQIA 3WHSA 2XVWA 2XMOA 2XSIA 3FWCC 4L9QA 2DBWA 2EFDA 2ROHA 3A75A 3H3AA 4EMXA 4WA6B 3NVIA 4HGMB 2BX8A 1E7AA 2VUFA 1MA9A 4OR0A 5GHKA 2VUEA 4F5SA 4ZUXV 1TF0A 3B9MA 2BXGA 2XW0A 4IW2A 1E78A 5IJEA 4ZCGA 2KBZA 1TXUA 2BXQA 1KW2A 4FK5B 4PO0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I30 A;  4OT2 A;  1E7H A;  2BXF A;  4L9K A;  5IIH A;  3TDL A;  2XVU A;  4J2V A;  2BXP A;  3B9L A;  1GNJ A;  4LB2 A;  1E7B A;  5ID7 A;  2BXC A;  2YDF A;  1BM0 A;  2I2Z A;  2VDB A;  5IFO A;  1AO6 A;  1J78 A;  3LU6 A;  3JQZ A;  3V09 A;  1H9Z A;  4BKE A;  1HK3 A;  2BXM A;  4K2C A;  3V03 A;  5FUO A;  2BXB A;  3UIV A;  4F5V A;  5DBY A;  4IW1 A;  4Z69 A;  4LB9 A;  2BXI A;  1HK5 A;  4LA0 A;  3CX9 A;  2BXL A;  4ZBQ A;  1HA2 A;  2BXD A;  3LU7 A;  1E7I A;  3V08 A;  4K71 A;  4N0F D;  2XVQ A;  1N5U A;  5DQF A;  4S1Y A;  1E7E A;  1KXP D;  1HK2 A;  4N0U D;  3JRY A;  3LU8 A;  5IIX A;  2BXA A;  2BXN A;  2BXO A;  1E7C A;  1UOR A;  1E7G A;  4F5T A;  1BJ5 A;  1HK4 A;  4E99 A;  3SQJ A;  2XW1 A;  1GNI A;  5IIU A;  4F5U A;  1BKE A;  1J7E A;  2BXE A;  4ZBR A;  4LUF A;  3A73 A;  4JK4 A;  2XVV A;  1LOT A;  2BXH A;  4G04 A;  4HGK A;  1O9X A;  4G03 A;  5IJF A;  5HOZ A;  4LUH A;  1HK1 A;  5ID9 A;  5IJ5 A;  2BXK A;  4L8U A;  1E7F A;  2XVW A;  2XSI A;  4L9Q A;  4EMX A;  4HGM B;  2BX8 A;  1E7A A;  2VUF A;  1MA9 A;  4OR0 A;  5GHK A;  2VUE A;  1TF0 A;  3B9M A;  2BXG A;  2XW0 A;  4IW2 A;  1E78 A;  5IJE A;  4F5S A;  2BXQ A;  1KW2 A;  4PO0 A; 
#chains in the Genus database with same CATH topology
 5GIP A;  2DYM A;  1JNB A;  2I30 A;  4OT2 A;  2KWF A;  2Z8J A;  2DBX A;  3WHQ A;  3NVM A;  1E7H A;  3NVK A;  2BXF A;  4L9K A;  1IJG A;  3TDL A;  5IIH A;  2XVU A;  4J2V A;  2BXP A;  3B9L A;  4ZC6 A;  5GIN A;  1GNJ A;  2OT3 A;  3BPJ A;  1MIY A;  1MIV A;  4LB2 A;  1E7B A;  2JUH A;  5ID7 A;  4C31 B;  3NMU A;  1MUH A;  3FWB C;  2BXC A;  2YDF A;  1LNS A;  1BM0 A;  2I2Z A;  1FOU A;  2VDB A;  3GA9 L;  5IFO A;  1AO6 A;  4GDK B;  3W1S A;  1J78 A;  4NAW B;  2DG5 A;  2NQO A;  2V36 A;  2Z8I A;  2AJE A;  2E0Y A;  3LU6 A;  2EFC A;  3JQZ A;  1MUS A;  3V09 A;  1H9Z A;  4BKE A;  4FIP B;  2EFE A;  2NNW A;  1HK3 A;  3GQU A;  4ZBK A;  2BXM A;  2LQI A;  4K2C A;  3V03 A;  5FUO A;  2BXB A;  2GUT A;  3UIV A;  4F5V A;  5DBY A;  3GQX A;  4IW1 A;  4Z69 A;  3H37 A;  4LB9 A;  2BXI A;  1HK5 A;  4LA0 A;  2DBU A;  3M99 C;  1NT2 B;  2BXL A;  3CX9 A;  4ZBQ A;  4DHX B;  3FNM A;  1HA2 A;  3MHH B;  2QHB A;  3G9K D;  4TQ1 A;  2BXD A;  3LU7 A;  5B5T A;  1E7I A;  1KDX A;  3ICX A;  4GG2 A;  2E0X A;  4GDL B;  3KJL A;  4DM0 A;  2Z8K A;  3MHS B;  3V08 A;  4K71 A;  4N0F D;  2XVQ A;  1N5U A;  1H5W A;  2LQH A;  4Z9O A;  5DQF A;  4S1Y A;  1E7E A;  4TQ0 A;  1KXP D;  2EFH A;  1HK2 A;  4N3Z A;  3KIK A;  3WHR A;  4N0U D;  3JRY A;  2LOQ A;  2QM6 A;  4I9O A;  3LU8 A;  5D7G A;  5IIX A;  2BXA A;  2BXN A;  2BXO A;  1VFI A;  1E7C A;  1UOR A;  4GDX A;  1E7G A;  4FJC B;  4F5T A;  1BJ5 A;  1HK4 A;  3ECP A;  3SIV B;  2QMC A;  4E99 A;  4W4U B;  3SQJ A;  2XW1 A;  2DYO A;  1GNI A;  1VZS A;  2CKX A;  5IIU A;  5GIO A;  4F5U A;  2OZB B;  1MM8 A;  1BKE A;  1J7E A;  2BXE A;  4BY9 C;  1SB0 A;  4ZBR A;  4LUF A;  3A73 A;  4JK4 A;  2XVV A;  1LOT A;  2BXH A;  4G04 A;  4MBE C;  4OTT A;  2LXT A;  4M70 B;  4OTU A;  5BPK A;  4D7X A;  4HGK A;  3PLA A;  3SIU B;  4FK5 B;  1O9X A;  4G03 A;  1MIW A;  5IJF A;  4G01 A;  5HOZ A;  4LUH A;  1HK1 A;  5ID9 A;  5IJ5 A;  2BXK A;  2LXS A;  4L8U A;  1E7F A;  3VQI A;  3WHS A;  2XVW A;  2XMO A;  2XSI A;  3FWC C;  4L9Q A;  2K0N A;  2DBW A;  2EFD A;  2ROH A;  3A75 A;  3H3A A;  4EMX A;  4WA6 B;  3NVI A;  4HGM B;  2BX8 A;  1E7A A;  2VUF A;  1MA9 A;  4OR0 A;  5GHK A;  2VUE A;  4F5S A;  4ZUX V;  1TF0 A;  3B9M A;  2BXG A;  2XW0 A;  4IW2 A;  1E78 A;  5IJE A;  4ZCG A;  2KBZ A;  1TXU A;  2BXQ A;  1KW2 A;  2AGH B;  4PO0 A; 
#chains in the Genus database with same CATH homology
 5GIP A;  2DYM A;  1JNB A;  2I30 A;  4OT2 A;  2Z8J A;  2DBX A;  3NVM A;  1E7H A;  2BXF A;  4L9K A;  1IJG A;  3TDL A;  5IIH A;  2XVU A;  4J2V A;  2BXP A;  3B9L A;  4ZC6 A;  5GIN A;  1GNJ A;  2OT3 A;  1MIY A;  1MIV A;  4LB2 A;  2JUH A;  1E7B A;  5ID7 A;  4C31 B;  3NMU A;  3FWB C;  2BXC A;  2YDF A;  1LNS A;  1BM0 A;  2I2Z A;  1FOU A;  2VDB A;  3GA9 L;  5IFO A;  1AO6 A;  4GDK B;  3W1S A;  1J78 A;  4NAW B;  2DG5 A;  2NQO A;  2V36 A;  2Z8I A;  2AJE A;  2E0Y A;  3LU6 A;  2EFC A;  3JQZ A;  3V09 A;  1H9Z A;  4BKE A;  4FIP B;  2EFE A;  2NNW A;  1HK3 A;  3GQU A;  4ZBK A;  2BXM A;  4K2C A;  3V03 A;  5FUO A;  2BXB A;  3UIV A;  4F5V A;  5DBY A;  3GQX A;  4IW1 A;  4Z69 A;  3H37 A;  4LB9 A;  2BXI A;  1HK5 A;  4LA0 A;  2DBU A;  3M99 C;  1NT2 B;  2BXL A;  3CX9 A;  4ZBQ A;  4DHX B;  3FNM A;  1HA2 A;  3MHH B;  2QHB A;  3G9K D;  4TQ1 A;  2BXD A;  3LU7 A;  5B5T A;  1E7I A;  3ICX A;  4GG2 A;  2E0X A;  4GDL B;  3KJL A;  2Z8K A;  3MHS B;  3V08 A;  4K71 A;  4N0F D;  2XVQ A;  1N5U A;  1H5W A;  4Z9O A;  5DQF A;  3WHQ A;  4S1Y A;  1E7E A;  4TQ0 A;  1KXP D;  2EFH A;  1HK2 A;  4N3Z A;  3KIK A;  3WHR A;  4N0U D;  3JRY A;  2LOQ A;  2QM6 A;  3LU8 A;  5D7G A;  5IIX A;  2BXA A;  2BXN A;  2BXO A;  1VFI A;  1E7C A;  1UOR A;  4GDX A;  1E7G A;  4FJC B;  4F5T A;  1BJ5 A;  1HK4 A;  3SIV B;  2QMC A;  4E99 A;  4W4U B;  3SQJ A;  2XW1 A;  2DYO A;  1GNI A;  1VZS A;  2CKX A;  5IIU A;  5GIO A;  4F5U A;  2OZB B;  1BKE A;  1J7E A;  2BXE A;  4BY9 C;  4ZBR A;  4LUF A;  3A73 A;  4JK4 A;  2XVV A;  1LOT A;  2BXH A;  4G04 A;  4MBE C;  4OTT A;  4OTU A;  4M70 B;  5BPK A;  3NVK A;  3PLA A;  4HGK A;  3SIU B;  1O9X A;  4G03 A;  1MIW A;  5IJF A;  4G01 A;  5HOZ A;  4LUH A;  1HK1 A;  5ID9 A;  5IJ5 A;  2BXK A;  4L8U A;  1E7F A;  3VQI A;  3WHS A;  2XVW A;  2XMO A;  2XSI A;  3FWC C;  4L9Q A;  2DBW A;  2EFD A;  2ROH A;  3A75 A;  3H3A A;  4EMX A;  4WA6 B;  3NVI A;  4HGM B;  2BX8 A;  1E7A A;  2VUF A;  1MA9 A;  4OR0 A;  5GHK A;  2VUE A;  4F5S A;  4ZUX V;  1TF0 A;  3B9M A;  2BXG A;  2XW0 A;  4IW2 A;  1E78 A;  5IJE A;  4ZCG A;  2KBZ A;  1TXU A;  2BXQ A;  1KW2 A;  4FK5 B;  4PO0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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