3D3HA

Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from aquifex aeolicus and neryl moenomycin a
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
183
structure length
174
Chain Sequence
QKRFYVSIDKIPEHVINAFVATEDRNFWHHFGIDPVAIVRAAIQGGSTITQQLAKNLFLTRERTLERKIKEALLAIKIERTFDKKKIMELYLNQIYLGSGAYGVEAAAQVYFGKHVWELSLDEAALLAALPKAPAKYNPFYHPERALQRRNLVLKRMLEEGYITPEQYEEAVNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design.
pubmed doi rcsb
molecule tags Transferase/antibiotic
source organism Aquifex aeolicus
molecule keywords Penicillin-insensitive transglycosylase
total genus 59
structure length 174
sequence length 183
ec nomenclature ec 2.4.1.129: Peptidoglycan glycosyltransferase.
pdb deposition date 2008-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00912 Transgly Transglycosylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3810.10 Mainly Alpha Orthogonal Bundle Penicillin binding protein transpeptidase fold Biosynthetic peptidoglycan transglycosylase-like 3d3hA00
3VMSA 3DWKA 3D3HA 3FWLA 3NB6A 3VMQA 3VMRA 3ZG7B 3HZSA 3VMTA 3VMAA 2OLUA 2OLVA 3NB7A 2OQOA
chains in the Genus database with same CATH superfamily
3VMSA 3DWKA 3D3HA 3FWLA 3NB6A 3VMQA 3VMRA 3ZG7B 3HZSA 3VMTA 3VMAA 2OLUA 2OLVA 3NB7A 2OQOA
chains in the Genus database with same CATH topology
3VMSA 3DWKA 3D3HA 3FWLA 3NB6A 3VMQA 3VMRA 3ZG7B 3HZSA 3VMTA 3VMAA 2OLUA 2OLVA 3NB7A 2OQOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VMS A;  3DWK A;  3D3H A;  3FWL A;  3NB6 A;  3VMQ A;  3VMR A;  3ZG7 B;  3HZS A;  3VMT A;  3VMA A;  2OLU A;  2OLV A;  3NB7 A;  2OQO A; 
#chains in the Genus database with same CATH topology
 3VMS A;  3DWK A;  3D3H A;  3FWL A;  3NB6 A;  3VMQ A;  3VMR A;  3ZG7 B;  3HZS A;  3VMT A;  3VMA A;  2OLU A;  2OLV A;  3NB7 A;  2OQO A; 
#chains in the Genus database with same CATH homology
 3VMS A;  3DWK A;  3D3H A;  3FWL A;  3NB6 A;  3VMQ A;  3VMR A;  3ZG7 B;  3HZS A;  3VMT A;  3VMA A;  2OLU A;  2OLV A;  3NB7 A;  2OQO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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