3DXEA

Crystal structure of the intracellular domain of human app (t668a mutant) in complex with fe65-ptb2
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
124
structure length
124
Chain Sequence
FQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Amyloid beta A4 protein-binding family B member 1
total genus 36
structure length 124
sequence length 124
chains with identical sequence C
ec nomenclature
pdb deposition date 2008-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00640 PID Phosphotyrosine interaction domain (PTB/PID)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 3dxeA00
2D2QA 2IYBA 1U5EA 2Y7BA 3HK0A 2X18A 4HAWB 2LOZA 1MIZB 3ODWA 3GYOA 1FAOA 1EF1A 4A6HA 4ZRJA 2D10A 3BINA 1EAZA 2ROVA 5C5BB 5KQ4A 4NSWA 3U7DA 2DKPA 2CY5A 4IOYX 2LYDA 3IVFA 2RSGA 4HAUB 1DDVA 2YVCA 4HATB 4YONA 1MK9B 5D27A 2MKRA 2NMBA 3SO6A 4EKUA 4IFSA 3PEGA 4K17A 4P7IA 1BTNA 4CHJA 2RGNB 3WYFB 1WGQA 2H7EA 1OMWA 2GCLA 1XODA 1ZSQA 2RNRB 2CODA 2V76A 2ELBA 2GCJA 4KVGB 1SHCA 1KI1B 2N23A 4H8SA 1TXDA 3CIKA 3AJ4A 3PVWA 4HDQA 2K00A 2DLWA 1PMSA 3ZDTA 2VSZA 3HQCA 2BCJA 2Z0OA 4HAXB 5HE3A 4B6HA 2ELAA 5KCVA 1OY2A 1E5WA 1ISNA 2GJYA 3KZ1A 3U8ZA 2RUKB 3PP2A 3TCAA 1V61A 1UNRA 1UNQA 1FHWA 4Y94A 4F7UP 3LJUX 2COFA 3N7CA 3X23A 3D8FA 1NTVA 1V88A 2ADZA 4K81A 1FB8A 3OANA 1V5MA 4WSFA 2I5FA 2CRFA 4DX8A 3PSCA 2Z0PA 1X1FA 2D9VA 1H4RA 3TVVA 3SYXA 3P6AA 4YL8A 2EC1A 2W2XD 2RLOA 1ZM0A 1U27A 3AU4A 2D9ZA 4XWXA 1AQCA 1BAKA 2PZ1A 4PNKA 4HB2B 1V5PA 2D9WA 1NI2A 1ZC4B 4GN1A 4CYEA 2CAYA 2M14A 5J3QA 2LKOA 3SNHA 1K5GB 5JHGA 2Z0QA 2MDXA 4KHBB 1UNPA 5FI0A 4HB0B 4CHMA 5DHFB 1BTKA 2DN6A 3TO1A 3PG7A 1ZVRA 2YS3A 2P0HA 5LONB 1UPQA 5FI1A 1M7RA 2LG1A 3KRXA 2W2WA 1SGHA 1U5DA 4EJNA 1U2BA 1WJMA 3DXDA 1WGUA 1U29A 2UVMA 3V5WA 5EFXA 5JHHA 3A98B 1J19A 4L6EA 3KSYA 1V89A 1Y5OA 2EJ8A 2L2IA 2MFQA 2DYQA 1P6SA 1LB1A 5HE0A 2K2UA 2GS0A 1UEFA 2COAA 1GG3A 2DKQA 4A6FA 2DHKA 4HAVB 3RCPA 3SUZA 3VIAA 2KUPA 1MAIA 3GYPA 2E2XA 4PQ0A 2KCJA 3DXCA 1AWEA 2L1CA 2YS1A 1XKEA 4K2OA 3ML4A 4GMXB 1OQNA 4NY0A 3ULBA 2VKIA 1GC6A 3CXBB 1PFJA 3UZTA 2COCA 3QWMA 2AEHA 1X05A 3ODOA 4DBBA 1W1GA 5C79A 1MIXA 2H7DA 4HAYB 2Q13A 2D4QA 5CLQB 2J0KA 2P0FA 5D3VA 4Z2MB 3BJIA 1EGXA 1U5FA 2D11A 2DX5A 1DDWA 2AL6A 5HE1A 5C16A 1MPHA 1LW3A 2DHJA 5GOWB 4KAXB 4F7GA 1X1GA 4Z2NA 5D3YA 1DROA 1RRPB 1EVHA 4GXBA 3D8DA 3PVLA 5D3XA 2Y8GA 2J0JA 4KHAA 4WVFB 4BBKA 1DDMA 2CY4A 5DI9B 2YT1A 2Y8FA 2DX1A 1FOEA 4K2PA 2YF0A 4TKNA 4DX90 4F7HA 3HW2B 3ODXA 1NU2A 1BWNA 1W1DA 5KQ1A 3VOQA 1TQZA 1XR0B 2MWNB 3QBVB 2DFKA 4HHVA 1X86A 2EMTA 1B55A 2D9YA 1XCGA 2LOXA 2VRWB 1WG7A 1PLSA 1GC7A 2UZRA 1FGYA 2DHIA 1QQGA 4A6KA 4A6FB 2I5CA 2XQNM 5C6RA 3TFMA 2HTHB 4A5KA 5LOPB 4MK0A 2NZ8B 2QKLA 2DYNA 2FJLA 1QC6A 2J0MA 3D8EA 4GMVA 1XD4A 3QIJA 2ZPYA 2RVBB 2D9XA 1W1HA 4C0AA 4WJ7A 1RJ2A 3P7ZA 3F0WA 4HDOA 2OQBA 3TW1A 1MKEA 3FM8C 5L81A 3M1IB 5DH9B 1I7AA 2YSZA 1DBHA 1J0WA 1M7EA 1DYNA 1FGZA 1WVHA 2OTXA 2W2XC 2KGXB 3FEHA 1WJ1A 1P3RA 2YT0A 4DXAB 1I2HA 4ZRIA 3ZVRA 3SV1A 5C5BA 5D3WA 2YS5A 1ZC3B 2JP2A 2QKMA 4MY6A 2YRYA 3PZDA 4GZUA 1U5GA 1FHXA 4TYZA 2M38A 3MPXA 3F5RA 4HB3B 1UPRA 2IFSA 2LULA 5DIFB 3FSSA 1H10A 3O96A 2DA0A 2P0DA 4MT7A 1TJ6A 5JP4A 1K5DB 1WI1A 2I1JA 3MDBC 1V5UA 2ROZB 4ZRKA 2J59M 5J3YA 2R09A 2UZSA 4IAPA 3G9WA 1MK7B 2G35A 1KZ7A 2N0YA 3A8QA 1P5TA 3NSUA 2EMSA 1FHOA 2R0DA 4HAZB 5DHAB 3DXEA 3ULCA 2P8VA 1IRSA 4HB4B 3KRWA 1XX0A 4EMOA 3KY9A 3WA0A 1N3HA 3A8PA 2DTCA 3AU5A 5JLJB 3PVUA 2I1KA 2HE7A 4D0NB 1NTYA 5HE2A 1X11A 2K2JA 5J3TA 3T06A 4GPTB 1Y19B 4KHOA 1Q67A 1KZGA 5CLLB 1Z87A
chains in the Genus database with same CATH superfamily
2D2QA 2IYBA 1U5EA 2Y7BA 3HK0A 2X18A 4HAWB 2LOZA 1MIZB 3ODWA 3GYOA 1FAOA 1EF1A 4A6HA 4ZRJA 2D10A 3B77A 3BINA 1EAZA 2GUMA 2ROVA 5C5BB 5KQ4A 4QJ4B 4NSWA 3U7DA 2DKPA 2CY5A 4IOYX 2LYDA 3IVFA 2RSGA 4HAUB 1DDVA 2YVCA 4HATB 4YONA 1MK9B 5D27A 2MKRA 2NMBA 3SO6A 4EKUA 4IFSA 3PEGA 4K17A 4P7IA 1BTNA 4CHJA 4QJ3B 2RGNB 3WYFB 1WGQA 4KHBA 2H7EA 1OMWA 2GCLA 1XODA 1ZSQA 2RNRB 2CODA 2V76A 2ELBA 2GCJA 4KVGB 3NWFA 1SHCA 1KI1B 2N23A 4H8SA 1TXDA 3CIKA 3AJ4A 3PVWA 4HDQA 2K00A 2DLWA 1PMSA 3ZDTA 2VSZA 3HQCA 2BCJA 2Z0OA 4HAXB 5HE3A 4B6HA 2ELAA 5KCVA 1OY2A 1E5WA 1ISNA 2GJYA 3KZ1A 2KIGA 3U8ZA 2RUKB 3PP2A 3TCAA 1V61A 1UNRA 2FJUB 1UNQA 1FHWA 4Y94A 4F7UP 3LJUX 2KUQA 3NWDA 2COFA 2KIEA 3N7CA 3X23A 3D8FA 1NTVA 1V88A 2ADZA 4K81A 1FB8A 3OANA 1V5MA 4WSFA 4GOUA 2I5FA 2CRFA 4DX8A 3PSCA 2Z0PA 1X1FA 1T77A 2D9VA 1H4RA 3TVVA 3OHMB 3SYXA 3P6AA 4YL8A 2EC1A 2W2XD 4D6WA 2RLOA 1ZM0A 1U27A 3AU4A 2D9ZA 4XWXA 1AQCA 1BAKA 2PZ1A 4DIXA 4PNKA 4HB2B 1V5PA 2D9WA 1NI2A 2RRFA 1ZC4B 4GN1A 4CYEA 2CAYA 2M14A 5J3QA 2LKOA 3SNHA 1K5GB 5JHGA 2Z0QA 4OSNA 2MDXA 4KHBB 1UNPA 5FI0A 4HB0B 4CHMA 5DHFB 1BTKA 2DN6A 3TO1A 3PG7A 1ZVRA 2YS3A 2P0HA 5LONB 1UPQA 5FI1A 1M7RA 2LG1A 3KRXA 2W2WA 1SGHA 1U5DA 4EJNA 1U2BA 1WJMA 3DXDA 1WGUA 1U29A 2UVMA 3V5WA 5EFXA 5JHHA 3A98B 4CSQA 1J19A 4L6EA 3KSYA 1V89A 1Y5OA 2EJ8A 2L2IA 2MFQA 2DYQA 4QJ5B 1P6SA 1LB1A 5HE0A 2K2UA 2GS0A 1UEFA 4HSIA 2COAA 1GG3A 2DKQA 4A6FA 2DHKA 4HAVB 3RCPA 3SUZA 3VIAA 2KUPA 1MAIA 3GYPA 2E2XA 4PQ0A 2KCJA 3DXCA 1AWEA 2L1CA 2YS1A 1XKEA 4K2OA 3ML4A 4GMXB 1OQNA 4NY0A 3ULBA 2VKIA 1GC6A 2Z59A 3CXBB 1PFJA 3UZTA 2COCA 3FVCA 3QWMA 2AEHA 1X05A 3ODOA 4DBBA 1W1GA 5C79A 1MIXA 2H7DA 4HAYB 2Q13A 2D4QA 5CLQB 2J0KA 2P0FA 5D3VA 4Z2MB 3BJIA 1EGXA 1U5FA 2D11A 2DX5A 1DDWA 2AL6A 5HE1A 5C16A 1MPHA 1LW3A 2DHJA 3NWAA 5GOWB 4KAXB 4F7GA 1X1GA 4Z2NA 5D3YA 1DROA 1RRPB 1EVHA 2ZKMX 4GXBA 3D8DA 3PVLA 5D3XA 2Y8GA 2J0JA 4KHAA 4WVFB 4BBKA 1DDMA 2CY4A 2K49A 5DI9B 2YT1A 2Y8FA 2DX1A 1FOEA 4K2PA 2YF0A 4TKNA 4DX90 1MI1A 4F7HA 3HW2B 3ODXA 1NU2A 1BWNA 1W1DA 5KQ1A 3VOQA 1TQZA 1XR0B 2MWNB 3QBVB 2DFKA 4HHVA 1X86A 2EMTA 1B55A 2D9YA 1XCGA 2LOXA 2VRWB 1WG7A 4OT1A 1PLSA 2YT2A 2Z4DA 1GC7A 2UZRA 1FGYA 2DHIA 2K8EA 1QQGA 4A6KA 4A6FB 2I5CA 2R2YA 2XQNM 5C6RA 3TFMA 2HTHB 4A5KA 5LOPB 4MK0A 2NZ8B 2QKLA 2DYNA 2FJLA 1QC6A 2J0MA 3D8EA 4GMVA 1XD4A 3QIJA 2ZPYA 2RVBB 2D9XA 1W1HA 4C0AA 4WJ7A 1RJ2A 4L1RA 5I2SA 3P7ZA 3U12A 2Z13A 1ZYIA 3F0WA 4HDOA 2OQBA 3NW8A 3TW1A 1MKEA 3FM8C 5L81A 3M1IB 5DH9B 1I7AA 2YSZA 4GNKB 1DBHA 5I2MA 1J0WA 1M7EA 1DYNA 1FGZA 1WVHA 2OTXA 2W2XC 2KGXB 3FEHA 1WJ1A 1P3RA 2YT0A 4DXAB 1I2HA 4ZRIA 3ZVRA 3SV1A 3DCXA 5D3WA 2YS5A 5C5BA 1ZC3B 2JP2A 2QKMA 4MY6A 3HIEA 2YRYA 3PZDA 4GZUA 1U5GA 5M4YB 1FHXA 4TYZA 2M38A 3MPXA 3F5RA 4HB3B 1UPRA 2IFSA 2LULA 4QXAB 5DIFB 3FSSA 1H10A 3O96A 5LG4B 2DA0A 2P0DA 4MT7A 1TJ6A 5JP4A 1K5DB 1WI1A 2I1JA 3MDBC 5IRSA 1V5UA 2ROZB 4ZRKA 2J59M 5J3YA 2R09A 2UZSA 4IAPA 3G9WA 2Z14A 1MK7B 2G35A 1KZ7A 2N0YA 3A8QA 1P5TA 2KR0A 3NSUA 2EMSA 1FHOA 2R0DA 4HAZB 5DHAB 3DXEA 3ULCA 2P8VA 1IRSA 3HSAA 4HB4B 3KRWA 1XX0A 4EMOA 3KY9A 3WA0A 1N3HA 3A8PA 2DTCA 3AU5A 3A58A 5JLJB 3PVUA 2I1KA 2HE7A 4D0NB 1NTYA 5HE2A 1X11A 2K2JA 5J3TA 3T06A 2NBVA 4GPTB 1Y19B 4KHOA 1Q67A 1KZGA 5CLLB 1Z87A
chains in the Genus database with same CATH topology
2D2QA 2IYBA 1U5EA 2Y7BA 3HK0A 2X18A 4HAWB 2LOZA 1MIZB 3ODWA 3GYOA 1FAOA 1EF1A 4A6HA 4ZRJA 2D10A 3BINA 1EAZA 2ROVA 5C5BB 5KQ4A 4NSWA 3U7DA 2DKPA 2CY5A 4IOYX 2LYDA 3IVFA 2RSGA 4HAUB 1DDVA 2YVCA 4HATB 4YONA 1MK9B 5D27A 2MKRA 2NMBA 3SO6A 4EKUA 4IFSA 3PEGA 4K17A 4P7IA 1BTNA 4CHJA 2RGNB 3WYFB 1WGQA 2H7EA 1OMWA 2GCLA 1XODA 1ZSQA 2RNRB 2CODA 2V76A 2ELBA 2GCJA 4KVGB 1SHCA 1KI1B 2N23A 4H8SA 1TXDA 3CIKA 3AJ4A 3PVWA 4HDQA 2K00A 2DLWA 1PMSA 3ZDTA 2VSZA 3HQCA 2BCJA 2Z0OA 4HAXB 5HE3A 4B6HA 2ELAA 5KCVA 1OY2A 1E5WA 1ISNA 2GJYA 3KZ1A 3U8ZA 2RUKB 3PP2A 3TCAA 1V61A 1UNRA 1UNQA 1FHWA 4Y94A 4F7UP 3LJUX 2COFA 3N7CA 3X23A 3D8FA 1NTVA 1V88A 2ADZA 4K81A 1FB8A 3OANA 1V5MA 4WSFA 2I5FA 2CRFA 4DX8A 3PSCA 2Z0PA 1X1FA 2D9VA 1H4RA 3TVVA 3SYXA 3P6AA 4YL8A 2EC1A 2W2XD 2RLOA 1ZM0A 1U27A 3AU4A 2D9ZA 4XWXA 1AQCA 1BAKA 2PZ1A 4PNKA 4HB2B 1V5PA 2D9WA 1NI2A 1ZC4B 4GN1A 4CYEA 2CAYA 2M14A 5J3QA 2LKOA 3SNHA 1K5GB 5JHGA 2Z0QA 2MDXA 4KHBB 1UNPA 5FI0A 4HB0B 4CHMA 5DHFB 1BTKA 2DN6A 3TO1A 3PG7A 1ZVRA 2YS3A 2P0HA 5LONB 1UPQA 5FI1A 1M7RA 2LG1A 3KRXA 2W2WA 1SGHA 1U5DA 4EJNA 1U2BA 1WJMA 3DXDA 1WGUA 1U29A 2UVMA 3V5WA 5EFXA 5JHHA 3A98B 1J19A 4L6EA 3KSYA 1V89A 1Y5OA 2EJ8A 2L2IA 2MFQA 2DYQA 1P6SA 1LB1A 5HE0A 2K2UA 2GS0A 1UEFA 2COAA 1GG3A 2DKQA 4A6FA 2DHKA 4HAVB 3RCPA 3SUZA 3VIAA 2KUPA 1MAIA 3GYPA 2E2XA 4PQ0A 2KCJA 3DXCA 1AWEA 2L1CA 2YS1A 1XKEA 4K2OA 3ML4A 4GMXB 1OQNA 4NY0A 3ULBA 2VKIA 1GC6A 3CXBB 1PFJA 3UZTA 2COCA 3QWMA 2AEHA 1X05A 3ODOA 4DBBA 1W1GA 5C79A 1MIXA 2H7DA 4HAYB 2Q13A 2D4QA 5CLQB 2J0KA 2P0FA 5D3VA 4Z2MB 3BJIA 1EGXA 1U5FA 2D11A 2DX5A 1DDWA 2AL6A 5HE1A 5C16A 1MPHA 1LW3A 2DHJA 5GOWB 4KAXB 4F7GA 1X1GA 4Z2NA 5D3YA 1DROA 1RRPB 1EVHA 4GXBA 3D8DA 3PVLA 5D3XA 2Y8GA 2J0JA 4KHAA 4WVFB 4BBKA 1DDMA 2CY4A 5DI9B 2YT1A 2Y8FA 2DX1A 1FOEA 4K2PA 2YF0A 4TKNA 4DX90 4F7HA 3HW2B 3ODXA 1NU2A 1BWNA 1W1DA 5KQ1A 3VOQA 1TQZA 1XR0B 2MWNB 3QBVB 2DFKA 4HHVA 1X86A 2EMTA 1B55A 2D9YA 1XCGA 2LOXA 2VRWB 1WG7A 1PLSA 1GC7A 2UZRA 1FGYA 2DHIA 1QQGA 4A6KA 4A6FB 2I5CA 2XQNM 5C6RA 3TFMA 2HTHB 4A5KA 5LOPB 4MK0A 2NZ8B 2QKLA 2DYNA 2FJLA 1QC6A 2J0MA 3D8EA 4GMVA 1XD4A 3QIJA 2ZPYA 2RVBB 2D9XA 1W1HA 4C0AA 4WJ7A 1RJ2A 3P7ZA 3F0WA 4HDOA 2OQBA 3TW1A 1MKEA 3FM8C 5L81A 3M1IB 5DH9B 1I7AA 2YSZA 1DBHA 1J0WA 1M7EA 1DYNA 1FGZA 1WVHA 2OTXA 2W2XC 2KGXB 3FEHA 1WJ1A 1P3RA 2YT0A 4DXAB 1I2HA 4ZRIA 3ZVRA 3SV1A 5C5BA 5D3WA 2YS5A 1ZC3B 2JP2A 2QKMA 4MY6A 2YRYA 3PZDA 4GZUA 1U5GA 1FHXA 4TYZA 2M38A 3MPXA 3F5RA 4HB3B 1UPRA 2IFSA 2LULA 5DIFB 3FSSA 1H10A 3O96A 2DA0A 2P0DA 4MT7A 1TJ6A 5JP4A 1K5DB 1WI1A 2I1JA 3MDBC 1V5UA 2ROZB 4ZRKA 2J59M 5J3YA 2R09A 2UZSA 4IAPA 3G9WA 1MK7B 2G35A 1KZ7A 2N0YA 3A8QA 1P5TA 3NSUA 2EMSA 1FHOA 2R0DA 4HAZB 5DHAB 3DXEA 3ULCA 2P8VA 1IRSA 4HB4B 3KRWA 1XX0A 4EMOA 3KY9A 3WA0A 1N3HA 3A8PA 2DTCA 3AU5A 5JLJB 3PVUA 2I1KA 2HE7A 4D0NB 1NTYA 5HE2A 1X11A 2K2JA 5J3TA 3T06A 4GPTB 1Y19B 4KHOA 1Q67A 1KZGA 5CLLB 1Z87A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D2Q A;  2IYB A;  1U5E A;  2Y7B A;  3HK0 A;  2X18 A;  4HAW B;  2LOZ A;  1MIZ B;  3ODW A;  3GYO A;  1FAO A;  1EF1 A;  4A6H A;  4ZRJ A;  2D10 A;  3BIN A;  1EAZ A;  2ROV A;  5C5B B;  5KQ4 A;  4NSW A;  3U7D A;  2DKP A;  2CY5 A;  4IOY X;  2LYD A;  3IVF A;  2RSG A;  4HAU B;  1DDV A;  2YVC A;  4HAT B;  4YON A;  1MK9 B;  5D27 A;  2MKR A;  2NMB A;  3SO6 A;  4EKU A;  4IFS A;  3PEG A;  4K17 A;  4P7I A;  1BTN A;  4CHJ A;  2RGN B;  3WYF B;  1WGQ A;  2H7E A;  1OMW A;  2GCL A;  1XOD A;  1ZSQ A;  2RNR B;  2COD A;  2V76 A;  2ELB A;  2GCJ A;  4KVG B;  1SHC A;  1KI1 B;  2N23 A;  4H8S A;  1TXD A;  3CIK A;  3AJ4 A;  3PVW A;  4HDQ A;  2K00 A;  2DLW A;  1PMS A;  3ZDT A;  2VSZ A;  3HQC A;  2BCJ A;  2Z0O A;  4HAX B;  5HE3 A;  4B6H A;  2ELA A;  5KCV A;  1OY2 A;  1E5W A;  1ISN A;  2GJY A;  3KZ1 A;  3U8Z A;  2RUK B;  3PP2 A;  3TCA A;  1V61 A;  1UNR A;  1UNQ A;  1FHW A;  4Y94 A;  4F7U P;  3LJU X;  2COF A;  3N7C A;  3X23 A;  3D8F A;  1NTV A;  1V88 A;  2ADZ A;  4K81 A;  1FB8 A;  3OAN A;  1V5M A;  4WSF A;  2I5F A;  2CRF A;  4DX8 A;  3PSC A;  2Z0P A;  1X1F A;  2D9V A;  1H4R A;  3TVV A;  3SYX A;  3P6A A;  4YL8 A;  2EC1 A;  2W2X D;  2RLO A;  1ZM0 A;  1U27 A;  3AU4 A;  2D9Z A;  4XWX A;  1AQC A;  1BAK A;  2PZ1 A;  4PNK A;  4HB2 B;  1V5P A;  2D9W A;  1NI2 A;  1ZC4 B;  4GN1 A;  4CYE A;  2CAY A;  2M14 A;  5J3Q A;  2LKO A;  3SNH A;  1K5G B;  5JHG A;  2Z0Q A;  2MDX A;  4KHB B;  1UNP A;  5FI0 A;  4HB0 B;  4CHM A;  5DHF B;  1BTK A;  2DN6 A;  3TO1 A;  3PG7 A;  1ZVR A;  2YS3 A;  2P0H A;  5LON B;  1UPQ A;  5FI1 A;  1M7R A;  2LG1 A;  3KRX A;  2W2W A;  1SGH A;  1U5D A;  4EJN A;  1U2B A;  1WJM A;  3DXD A;  1WGU A;  1U29 A;  2UVM A;  3V5W A;  5EFX A;  5JHH A;  3A98 B;  1J19 A;  4L6E A;  3KSY A;  1V89 A;  1Y5O A;  2EJ8 A;  2L2I A;  2MFQ A;  2DYQ A;  1P6S A;  1LB1 A;  5HE0 A;  2K2U A;  2GS0 A;  1UEF A;  2COA A;  1GG3 A;  2DKQ A;  4A6F A;  2DHK A;  4HAV B;  3RCP A;  3SUZ A;  3VIA A;  2KUP A;  1MAI A;  3GYP A;  2E2X A;  4PQ0 A;  2KCJ A;  3DXC A;  1AWE A;  2L1C A;  2YS1 A;  1XKE A;  4K2O A;  3ML4 A;  4GMX B;  1OQN A;  4NY0 A;  3ULB A;  2VKI A;  1GC6 A;  3CXB B;  1PFJ A;  3UZT A;  2COC A;  3QWM A;  2AEH A;  1X05 A;  3ODO A;  4DBB A;  1W1G A;  5C79 A;  1MIX A;  2H7D A;  4HAY B;  2Q13 A;  2D4Q A;  5CLQ B;  2J0K A;  2P0F A;  5D3V A;  4Z2M B;  3BJI A;  1EGX A;  1U5F A;  2D11 A;  2DX5 A;  1DDW A;  2AL6 A;  5HE1 A;  5C16 A;  1MPH A;  1LW3 A;  2DHJ A;  5GOW B;  4KAX B;  4F7G A;  1X1G A;  4Z2N A;  5D3Y A;  1DRO A;  1RRP B;  1EVH A;  4GXB A;  3D8D A;  3PVL A;  5D3X A;  2Y8G A;  2J0J A;  4KHA A;  4WVF B;  4BBK A;  1DDM A;  2CY4 A;  5DI9 B;  2YT1 A;  2Y8F A;  2DX1 A;  1FOE A;  4K2P A;  2YF0 A;  4TKN A;  4DX9 0;  4F7H A;  3HW2 B;  3ODX A;  1NU2 A;  1BWN A;  1W1D A;  5KQ1 A;  3VOQ A;  1TQZ A;  1XR0 B;  2MWN B;  3QBV B;  2DFK A;  4HHV A;  1X86 A;  2EMT A;  1B55 A;  2D9Y A;  1XCG A;  2LOX A;  2VRW B;  1WG7 A;  1PLS A;  1GC7 A;  2UZR A;  1FGY A;  2DHI A;  1QQG A;  4A6K A;  4A6F B;  2I5C A;  2XQN M;  5C6R A;  3TFM A;  2HTH B;  4A5K A;  5LOP B;  4MK0 A;  2NZ8 B;  2QKL A;  2DYN A;  2FJL A;  1QC6 A;  2J0M A;  3D8E A;  4GMV A;  1XD4 A;  3QIJ A;  2ZPY A;  2RVB B;  2D9X A;  1W1H A;  4C0A A;  4WJ7 A;  1RJ2 A;  3P7Z A;  3F0W A;  4HDO A;  2OQB A;  3TW1 A;  1MKE A;  3FM8 C;  5L81 A;  3M1I B;  5DH9 B;  1I7A A;  2YSZ A;  1DBH A;  1J0W A;  1M7E A;  1DYN A;  1FGZ A;  1WVH A;  2OTX A;  2W2X C;  2KGX B;  3FEH A;  1WJ1 A;  1P3R A;  2YT0 A;  4DXA B;  1I2H A;  4ZRI A;  3ZVR A;  3SV1 A;  5C5B A;  5D3W A;  2YS5 A;  1ZC3 B;  2JP2 A;  2QKM A;  4MY6 A;  2YRY A;  3PZD A;  4GZU A;  1U5G A;  1FHX A;  4TYZ A;  2M38 A;  3MPX A;  3F5R A;  4HB3 B;  1UPR A;  2IFS A;  2LUL A;  5DIF B;  3FSS A;  1H10 A;  3O96 A;  2DA0 A;  2P0D A;  4MT7 A;  1TJ6 A;  5JP4 A;  1K5D B;  1WI1 A;  2I1J A;  3MDB C;  1V5U A;  2ROZ B;  4ZRK A;  2J59 M;  5J3Y A;  2R09 A;  2UZS A;  4IAP A;  3G9W A;  1MK7 B;  2G35 A;  1KZ7 A;  2N0Y A;  3A8Q A;  1P5T A;  3NSU A;  2EMS A;  1FHO A;  2R0D A;  4HAZ B;  5DHA B;  3DXE A;  3ULC A;  2P8V A;  1IRS A;  4HB4 B;  3KRW A;  1XX0 A;  4EMO A;  3KY9 A;  3WA0 A;  1N3H A;  3A8P A;  2DTC A;  3AU5 A;  5JLJ B;  3PVU A;  2I1K A;  2HE7 A;  4D0N B;  1NTY A;  5HE2 A;  1X11 A;  2K2J A;  5J3T A;  3T06 A;  4GPT B;  1Y19 B;  4KHO A;  1Q67 A;  1KZG A;  5CLL B;  1Z87 A; 
#chains in the Genus database with same CATH topology
 2D2Q A;  2IYB A;  1U5E A;  2Y7B A;  3HK0 A;  2X18 A;  4HAW B;  2LOZ A;  1MIZ B;  3ODW A;  3GYO A;  1FAO A;  1EF1 A;  4A6H A;  4ZRJ A;  2D10 A;  3B77 A;  3BIN A;  1EAZ A;  2GUM A;  2ROV A;  5C5B B;  5KQ4 A;  4QJ4 B;  4NSW A;  3U7D A;  2DKP A;  2CY5 A;  4IOY X;  2LYD A;  3IVF A;  2RSG A;  4HAU B;  1DDV A;  2YVC A;  4HAT B;  4YON A;  1MK9 B;  5D27 A;  2MKR A;  2NMB A;  3SO6 A;  4EKU A;  4IFS A;  3PEG A;  4K17 A;  4P7I A;  1BTN A;  4CHJ A;  4QJ3 B;  2RGN B;  3WYF B;  1WGQ A;  4KHB A;  2H7E A;  1OMW A;  2GCL A;  1XOD A;  1ZSQ A;  2RNR B;  2COD A;  2V76 A;  2ELB A;  2GCJ A;  4KVG B;  3NWF A;  1SHC A;  1KI1 B;  2N23 A;  4H8S A;  1TXD A;  3CIK A;  3AJ4 A;  3PVW A;  4HDQ A;  2K00 A;  2DLW A;  1PMS A;  3ZDT A;  2VSZ A;  3HQC A;  2BCJ A;  2Z0O A;  4HAX B;  5HE3 A;  4B6H A;  2ELA A;  5KCV A;  1OY2 A;  1E5W A;  1ISN A;  2GJY A;  3KZ1 A;  2KIG A;  3U8Z A;  2RUK B;  3PP2 A;  3TCA A;  1V61 A;  1UNR A;  2FJU B;  1UNQ A;  1FHW A;  4Y94 A;  4F7U P;  3LJU X;  2KUQ A;  3NWD A;  2COF A;  2KIE A;  3N7C A;  3X23 A;  3D8F A;  1NTV A;  1V88 A;  2ADZ A;  4K81 A;  1FB8 A;  3OAN A;  1V5M A;  4WSF A;  4GOU A;  2I5F A;  2CRF A;  4DX8 A;  3PSC A;  2Z0P A;  1X1F A;  1T77 A;  2D9V A;  1H4R A;  3TVV A;  3OHM B;  3SYX A;  3P6A A;  4YL8 A;  2EC1 A;  2W2X D;  4D6W A;  2RLO A;  1ZM0 A;  1U27 A;  3AU4 A;  2D9Z A;  4XWX A;  1AQC A;  1BAK A;  2PZ1 A;  4DIX A;  4PNK A;  4HB2 B;  1V5P A;  2D9W A;  1NI2 A;  2RRF A;  1ZC4 B;  4GN1 A;  4CYE A;  2CAY A;  2M14 A;  5J3Q A;  2LKO A;  3SNH A;  1K5G B;  5JHG A;  2Z0Q A;  4OSN A;  2MDX A;  4KHB B;  1UNP A;  5FI0 A;  4HB0 B;  4CHM A;  5DHF B;  1BTK A;  2DN6 A;  3TO1 A;  3PG7 A;  1ZVR A;  2YS3 A;  2P0H A;  5LON B;  1UPQ A;  5FI1 A;  1M7R A;  2LG1 A;  3KRX A;  2W2W A;  1SGH A;  1U5D A;  4EJN A;  1U2B A;  1WJM A;  3DXD A;  1WGU A;  1U29 A;  2UVM A;  3V5W A;  5EFX A;  5JHH A;  3A98 B;  4CSQ A;  1J19 A;  4L6E A;  3KSY A;  1V89 A;  1Y5O A;  2EJ8 A;  2L2I A;  2MFQ A;  2DYQ A;  4QJ5 B;  1P6S A;  1LB1 A;  5HE0 A;  2K2U A;  2GS0 A;  1UEF A;  4HSI A;  2COA A;  1GG3 A;  2DKQ A;  4A6F A;  2DHK A;  4HAV B;  3RCP A;  3SUZ A;  3VIA A;  2KUP A;  1MAI A;  3GYP A;  2E2X A;  4PQ0 A;  2KCJ A;  3DXC A;  1AWE A;  2L1C A;  2YS1 A;  1XKE A;  4K2O A;  3ML4 A;  4GMX B;  1OQN A;  4NY0 A;  3ULB A;  2VKI A;  1GC6 A;  2Z59 A;  3CXB B;  1PFJ A;  3UZT A;  2COC A;  3FVC A;  3QWM A;  2AEH A;  1X05 A;  3ODO A;  4DBB A;  1W1G A;  5C79 A;  1MIX A;  2H7D A;  4HAY B;  2Q13 A;  2D4Q A;  5CLQ B;  2J0K A;  2P0F A;  5D3V A;  4Z2M B;  3BJI A;  1EGX A;  1U5F A;  2D11 A;  2DX5 A;  1DDW A;  2AL6 A;  5HE1 A;  5C16 A;  1MPH A;  1LW3 A;  2DHJ A;  3NWA A;  5GOW B;  4KAX B;  4F7G A;  1X1G A;  4Z2N A;  5D3Y A;  1DRO A;  1RRP B;  1EVH A;  2ZKM X;  4GXB A;  3D8D A;  3PVL A;  5D3X A;  2Y8G A;  2J0J A;  4KHA A;  4WVF B;  4BBK A;  1DDM A;  2CY4 A;  2K49 A;  5DI9 B;  2YT1 A;  2Y8F A;  2DX1 A;  1FOE A;  4K2P A;  2YF0 A;  4TKN A;  4DX9 0;  1MI1 A;  4F7H A;  3HW2 B;  3ODX A;  1NU2 A;  1BWN A;  1W1D A;  5KQ1 A;  3VOQ A;  1TQZ A;  1XR0 B;  2MWN B;  3QBV B;  2DFK A;  4HHV A;  1X86 A;  2EMT A;  1B55 A;  2D9Y A;  1XCG A;  2LOX A;  2VRW B;  1WG7 A;  4OT1 A;  1PLS A;  2YT2 A;  2Z4D A;  1GC7 A;  2UZR A;  1FGY A;  2DHI A;  2K8E A;  1QQG A;  4A6K A;  4A6F B;  2I5C A;  2R2Y A;  2XQN M;  5C6R A;  3TFM A;  2HTH B;  4A5K A;  5LOP B;  4MK0 A;  2NZ8 B;  2QKL A;  2DYN A;  2FJL A;  1QC6 A;  2J0M A;  3D8E A;  4GMV A;  1XD4 A;  3QIJ A;  2ZPY A;  2RVB B;  2D9X A;  1W1H A;  4C0A A;  4WJ7 A;  1RJ2 A;  4L1R A;  5I2S A;  3P7Z A;  3U12 A;  2Z13 A;  1ZYI A;  3F0W A;  4HDO A;  2OQB A;  3NW8 A;  3TW1 A;  1MKE A;  3FM8 C;  5L81 A;  3M1I B;  5DH9 B;  1I7A A;  2YSZ A;  4GNK B;  1DBH A;  5I2M A;  1J0W A;  1M7E A;  1DYN A;  1FGZ A;  1WVH A;  2OTX A;  2W2X C;  2KGX B;  3FEH A;  1WJ1 A;  1P3R A;  2YT0 A;  4DXA B;  1I2H A;  4ZRI A;  3ZVR A;  3SV1 A;  3DCX A;  5D3W A;  2YS5 A;  5C5B A;  1ZC3 B;  2JP2 A;  2QKM A;  4MY6 A;  3HIE A;  2YRY A;  3PZD A;  4GZU A;  1U5G A;  5M4Y B;  1FHX A;  4TYZ A;  2M38 A;  3MPX A;  3F5R A;  4HB3 B;  1UPR A;  2IFS A;  2LUL A;  4QXA B;  5DIF B;  3FSS A;  1H10 A;  3O96 A;  5LG4 B;  2DA0 A;  2P0D A;  4MT7 A;  1TJ6 A;  5JP4 A;  1K5D B;  1WI1 A;  2I1J A;  3MDB C;  5IRS A;  1V5U A;  2ROZ B;  4ZRK A;  2J59 M;  5J3Y A;  2R09 A;  2UZS A;  4IAP A;  3G9W A;  2Z14 A;  1MK7 B;  2G35 A;  1KZ7 A;  2N0Y A;  3A8Q A;  1P5T A;  2KR0 A;  3NSU A;  2EMS A;  1FHO A;  2R0D A;  4HAZ B;  5DHA B;  3DXE A;  3ULC A;  2P8V A;  1IRS A;  3HSA A;  4HB4 B;  3KRW A;  1XX0 A;  4EMO A;  3KY9 A;  3WA0 A;  1N3H A;  3A8P A;  2DTC A;  3AU5 A;  3A58 A;  5JLJ B;  3PVU A;  2I1K A;  2HE7 A;  4D0N B;  1NTY A;  5HE2 A;  1X11 A;  2K2J A;  5J3T A;  3T06 A;  2NBV A;  4GPT B;  1Y19 B;  4KHO A;  1Q67 A;  1KZG A;  5CLL B;  1Z87 A; 
#chains in the Genus database with same CATH homology
 2D2Q A;  2IYB A;  1U5E A;  2Y7B A;  3HK0 A;  2X18 A;  4HAW B;  2LOZ A;  1MIZ B;  3ODW A;  3GYO A;  1FAO A;  1EF1 A;  4A6H A;  4ZRJ A;  2D10 A;  3BIN A;  1EAZ A;  2ROV A;  5C5B B;  5KQ4 A;  4NSW A;  3U7D A;  2DKP A;  2CY5 A;  4IOY X;  2LYD A;  3IVF A;  2RSG A;  4HAU B;  1DDV A;  2YVC A;  4HAT B;  4YON A;  1MK9 B;  5D27 A;  2MKR A;  2NMB A;  3SO6 A;  4EKU A;  4IFS A;  3PEG A;  4K17 A;  4P7I A;  1BTN A;  4CHJ A;  2RGN B;  3WYF B;  1WGQ A;  2H7E A;  1OMW A;  2GCL A;  1XOD A;  1ZSQ A;  2RNR B;  2COD A;  2V76 A;  2ELB A;  2GCJ A;  4KVG B;  1SHC A;  1KI1 B;  2N23 A;  4H8S A;  1TXD A;  3CIK A;  3AJ4 A;  3PVW A;  4HDQ A;  2K00 A;  2DLW A;  1PMS A;  3ZDT A;  2VSZ A;  3HQC A;  2BCJ A;  2Z0O A;  4HAX B;  5HE3 A;  4B6H A;  2ELA A;  5KCV A;  1OY2 A;  1E5W A;  1ISN A;  2GJY A;  3KZ1 A;  3U8Z A;  2RUK B;  3PP2 A;  3TCA A;  1V61 A;  1UNR A;  1UNQ A;  1FHW A;  4Y94 A;  4F7U P;  3LJU X;  2COF A;  3N7C A;  3X23 A;  3D8F A;  1NTV A;  1V88 A;  2ADZ A;  4K81 A;  1FB8 A;  3OAN A;  1V5M A;  4WSF A;  2I5F A;  2CRF A;  4DX8 A;  3PSC A;  2Z0P A;  1X1F A;  2D9V A;  1H4R A;  3TVV A;  3SYX A;  3P6A A;  4YL8 A;  2EC1 A;  2W2X D;  2RLO A;  1ZM0 A;  1U27 A;  3AU4 A;  2D9Z A;  4XWX A;  1AQC A;  1BAK A;  2PZ1 A;  4PNK A;  4HB2 B;  1V5P A;  2D9W A;  1NI2 A;  1ZC4 B;  4GN1 A;  4CYE A;  2CAY A;  2M14 A;  5J3Q A;  2LKO A;  3SNH A;  1K5G B;  5JHG A;  2Z0Q A;  2MDX A;  4KHB B;  1UNP A;  5FI0 A;  4HB0 B;  4CHM A;  5DHF B;  1BTK A;  2DN6 A;  3TO1 A;  3PG7 A;  1ZVR A;  2YS3 A;  2P0H A;  5LON B;  1UPQ A;  5FI1 A;  1M7R A;  2LG1 A;  3KRX A;  2W2W A;  1SGH A;  1U5D A;  4EJN A;  1U2B A;  1WJM A;  3DXD A;  1WGU A;  1U29 A;  2UVM A;  3V5W A;  5EFX A;  5JHH A;  3A98 B;  1J19 A;  4L6E A;  3KSY A;  1V89 A;  1Y5O A;  2EJ8 A;  2L2I A;  2MFQ A;  2DYQ A;  1P6S A;  1LB1 A;  5HE0 A;  2K2U A;  2GS0 A;  1UEF A;  2COA A;  1GG3 A;  2DKQ A;  4A6F A;  2DHK A;  4HAV B;  3RCP A;  3SUZ A;  3VIA A;  2KUP A;  1MAI A;  3GYP A;  2E2X A;  4PQ0 A;  2KCJ A;  3DXC A;  1AWE A;  2L1C A;  2YS1 A;  1XKE A;  4K2O A;  3ML4 A;  4GMX B;  1OQN A;  4NY0 A;  3ULB A;  2VKI A;  1GC6 A;  3CXB B;  1PFJ A;  3UZT A;  2COC A;  3QWM A;  2AEH A;  1X05 A;  3ODO A;  4DBB A;  1W1G A;  5C79 A;  1MIX A;  2H7D A;  4HAY B;  2Q13 A;  2D4Q A;  5CLQ B;  2J0K A;  2P0F A;  5D3V A;  4Z2M B;  3BJI A;  1EGX A;  1U5F A;  2D11 A;  2DX5 A;  1DDW A;  2AL6 A;  5HE1 A;  5C16 A;  1MPH A;  1LW3 A;  2DHJ A;  5GOW B;  4KAX B;  4F7G A;  1X1G A;  4Z2N A;  5D3Y A;  1DRO A;  1RRP B;  1EVH A;  4GXB A;  3D8D A;  3PVL A;  5D3X A;  2Y8G A;  2J0J A;  4KHA A;  4WVF B;  4BBK A;  1DDM A;  2CY4 A;  5DI9 B;  2YT1 A;  2Y8F A;  2DX1 A;  1FOE A;  4K2P A;  2YF0 A;  4TKN A;  4DX9 0;  4F7H A;  3HW2 B;  3ODX A;  1NU2 A;  1BWN A;  1W1D A;  5KQ1 A;  3VOQ A;  1TQZ A;  1XR0 B;  2MWN B;  3QBV B;  2DFK A;  4HHV A;  1X86 A;  2EMT A;  1B55 A;  2D9Y A;  1XCG A;  2LOX A;  2VRW B;  1WG7 A;  1PLS A;  1GC7 A;  2UZR A;  1FGY A;  2DHI A;  1QQG A;  4A6K A;  4A6F B;  2I5C A;  2XQN M;  5C6R A;  3TFM A;  2HTH B;  4A5K A;  5LOP B;  4MK0 A;  2NZ8 B;  2QKL A;  2DYN A;  2FJL A;  1QC6 A;  2J0M A;  3D8E A;  4GMV A;  1XD4 A;  3QIJ A;  2ZPY A;  2RVB B;  2D9X A;  1W1H A;  4C0A A;  4WJ7 A;  1RJ2 A;  3P7Z A;  3F0W A;  4HDO A;  2OQB A;  3TW1 A;  1MKE A;  3FM8 C;  5L81 A;  3M1I B;  5DH9 B;  1I7A A;  2YSZ A;  1DBH A;  1J0W A;  1M7E A;  1DYN A;  1FGZ A;  1WVH A;  2OTX A;  2W2X C;  2KGX B;  3FEH A;  1WJ1 A;  1P3R A;  2YT0 A;  4DXA B;  1I2H A;  4ZRI A;  3ZVR A;  3SV1 A;  5C5B A;  5D3W A;  2YS5 A;  1ZC3 B;  2JP2 A;  2QKM A;  4MY6 A;  2YRY A;  3PZD A;  4GZU A;  1U5G A;  1FHX A;  4TYZ A;  2M38 A;  3MPX A;  3F5R A;  4HB3 B;  1UPR A;  2IFS A;  2LUL A;  5DIF B;  3FSS A;  1H10 A;  3O96 A;  2DA0 A;  2P0D A;  4MT7 A;  1TJ6 A;  5JP4 A;  1K5D B;  1WI1 A;  2I1J A;  3MDB C;  1V5U A;  2ROZ B;  4ZRK A;  2J59 M;  5J3Y A;  2R09 A;  2UZS A;  4IAP A;  3G9W A;  1MK7 B;  2G35 A;  1KZ7 A;  2N0Y A;  3A8Q A;  1P5T A;  3NSU A;  2EMS A;  1FHO A;  2R0D A;  4HAZ B;  5DHA B;  3DXE A;  3ULC A;  2P8V A;  1IRS A;  4HB4 B;  3KRW A;  1XX0 A;  4EMO A;  3KY9 A;  3WA0 A;  1N3H A;  3A8P A;  2DTC A;  3AU5 A;  5JLJ B;  3PVU A;  2I1K A;  2HE7 A;  4D0N B;  1NTY A;  5HE2 A;  1X11 A;  2K2J A;  5J3T A;  3T06 A;  4GPT B;  1Y19 B;  4KHO A;  1Q67 A;  1KZG A;  5CLL B;  1Z87 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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