3DYCA

Structure of e322y alkaline phosphatase in complex with inorganic phosphate
Total Genus 156
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
Knots found
sequence length
446
structure length
446
Chain Sequence
b'MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVYGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Alkaline phosphatase
publication title Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal Ion.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 156
structure length 446
sequence length 446
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dycA00
5K4PA 1EW9A 5L0KA 1E1ZP 3UN3A 2W5VA 3WBHA 4UOOA 1ALJA 1K7HA 1ALKA 1Y6VA 4MIVA 1KH4A 3TWZA 1HQAA 4MY4A 3SZYA 2W8DA 1SHQA 3IDDA 3BDHA 3SZZA 3M8ZA 4ZGAA 1EI6A 2GSUA 4FDJA 3WAVA 1URAA 1N2KA 5LQQA 3Q3QA 4NWJA 4ZG9A 2VQRA 4KJDA 1O98A 5LRMA 1AJCA 5DLVA 3UN2A 3MK2A 2GLQA 4ZG6A 3CMRA 3T00A 1ED8A 1KHJA 5IJQA 2D1GA 5EGEA 5INHA 3WAXA 5DLTA 4CYRA 5AJ9A 3TX0A 1EJJA 1AUKA 1KH7A 3NVLA 4N7TA 1ZEDA 2W5SA 5GRRA 2GSNA 3M8YA 3IGYB 5HRTA 3MK0A 1B8JA 1ELYA 1KH5A 4KAYA 4CXUA 2W5XA 1FSUA 4UORA 5L0EA 2ANHA 1KHKA 3UN5A 1KH9A 3BDGB 1ZEFA 3DYCA 1KHLA 4FDIA 4LR2A 1Y7AA 4UPHA 1AJBA 3E2DA 4CXKA 4KAVA 1HJKA 2QZUA 3BDGA 1ALHA 4UPLA 3WAYA 4KJGA 1AJDA 4CYSA 1ANIA 2W8SA 3WAWA 1SHNA 2W5WA 2X98A 2RH6A 4UOPA 5IJSA 1ANJA 4GTYA 3NKNA 4GTWA 4GTZA 4YR1A 1ELZA 4UPIA 4TN0A 4LRDA 1ALIA 3M8WA 5EGHA 3DPCA 4LREA 3UNYA 3UO0A 4B56A 4UPKA 5C66A 2W5RA 3B5QA 1HDHA 1P49A 5GOVA 3MK1A 1URBA 2XRGA 4QAXA 5DLWA 2IFYA 3OT9A 1EQJA 4LR9A 5TJ3A 3NKMA 4NWXA 1ELXA 4LRBA 3NKOA 1ED9A 4LR7A 1E3CP 3A52A 1N2LA 4CXSA 5KXAA 4LRAA 4LRFA 1E33P 2ZKTA 3BDFA 3M7VA 2IUCB 3IGZB 1AJAA 4ZG7A 1EW2A 2W5QA 3T02A 5LRNA 3ED4A 1ZEBA 4LQYA 4LR8A 2IUCA 1KHNA 3KD8A 3T01A 2GA3A 2G9YA 3NKRA 2GSOA 1E2SP 3TG0A 1EW8A 2W5TA 1O99A 3LXQA 2XR9A 3NKQA 3NKPA 4GTXA 4KM4A 4MHXA 5LIAA 4LRCA 5L0BA
chains in the Genus database with same CATH superfamily
5K4PA 1EW9A 5L0KA 1E1ZP 3UN3A 2W5VA 3WBHA 4UOOA 1ALJA 1K7HA 1ALKA 1Y6VA 4MIVA 1KH4A 3TWZA 1HQAA 4MY4A 3SZYA 2W8DA 1SHQA 3IDDA 3BDHA 3SZZA 3M8ZA 4ZGAA 1EI6A 2GSUA 4FDJA 3WAVA 1URAA 1N2KA 5LQQA 3Q3QA 4NWJA 4ZG9A 2VQRA 4KJDA 1O98A 5LRMA 1AJCA 5DLVA 3UN2A 3MK2A 2GLQA 4ZG6A 3CMRA 3T00A 1ED8A 1KHJA 5IJQA 2D1GA 5EGEA 5INHA 3WAXA 5DLTA 4CYRA 5AJ9A 3TX0A 1EJJA 1AUKA 1KH7A 3NVLA 4N7TA 1ZEDA 2W5SA 5GRRA 2GSNA 3M8YA 3IGYB 5HRTA 3MK0A 1B8JA 1ELYA 1KH5A 4KAYA 4CXUA 2W5XA 1FSUA 4UORA 5L0EA 2ANHA 1KHKA 3UN5A 1KH9A 3BDGB 1ZEFA 3DYCA 1KHLA 4FDIA 4LR2A 1Y7AA 4UPHA 1AJBA 3E2DA 4CXKA 4KAVA 1HJKA 2QZUA 3BDGA 1ALHA 4UPLA 3WAYA 4KJGA 1AJDA 4CYSA 1ANIA 2W8SA 3WAWA 1SHNA 2W5WA 2X98A 2RH6A 4UOPA 5IJSA 1ANJA 4GTYA 3NKNA 4GTWA 4GTZA 4YR1A 1ELZA 4UPIA 4TN0A 4LRDA 1ALIA 3M8WA 5EGHA 3DPCA 4LREA 3UNYA 3UO0A 4B56A 4UPKA 5C66A 2W5RA 3B5QA 1HDHA 1P49A 5GOVA 3MK1A 1URBA 2XRGA 4QAXA 5DLWA 2IFYA 3OT9A 1EQJA 4LR9A 5TJ3A 3NKMA 4NWXA 1ELXA 4LRBA 3NKOA 1ED9A 4LR7A 1E3CP 3A52A 1N2LA 4CXSA 5KXAA 4LRAA 4LRFA 1E33P 2ZKTA 3BDFA 3M7VA 2IUCB 3IGZB 1AJAA 4ZG7A 1EW2A 2W5QA 3T02A 5LRNA 3ED4A 1ZEBA 4LQYA 4LR8A 2IUCA 1KHNA 3KD8A 3T01A 2GA3A 2G9YA 3NKRA 2GSOA 1E2SP 3TG0A 1EW8A 2W5TA 1O99A 3LXQA 2XR9A 3NKQA 3NKPA 4GTXA 4KM4A 4MHXA 5LIAA 4LRCA 5L0BA
chains in the Genus database with same CATH topology
5K4PA 1EW9A 5L0KA 1E1ZP 3UN3A 2W5VA 3WBHA 4UOOA 1ALJA 1K7HA 1ALKA 1Y6VA 4MIVA 1KH4A 3TWZA 1HQAA 4MY4A 3SZYA 2W8DA 1SHQA 3IDDA 3BDHA 3SZZA 3M8ZA 4ZGAA 1EI6A 2GSUA 4FDJA 3WAVA 1URAA 1N2KA 5LQQA 3Q3QA 4NWJA 4ZG9A 2VQRA 4KJDA 1O98A 5LRMA 1AJCA 5DLVA 3UN2A 3MK2A 2GLQA 4ZG6A 3CMRA 3T00A 1ED8A 1KHJA 5IJQA 2D1GA 5EGEA 5INHA 3WAXA 5DLTA 4CYRA 5AJ9A 3TX0A 1EJJA 1AUKA 1KH7A 3NVLA 4N7TA 1ZEDA 2W5SA 5GRRA 2GSNA 3M8YA 3IGYB 5HRTA 3MK0A 1B8JA 1ELYA 1KH5A 4KAYA 4CXUA 2W5XA 1FSUA 4UORA 5L0EA 2ANHA 1KHKA 3UN5A 1KH9A 3BDGB 1ZEFA 3DYCA 1KHLA 4FDIA 4LR2A 1Y7AA 4UPHA 1AJBA 3E2DA 4CXKA 4KAVA 1HJKA 2QZUA 3BDGA 1ALHA 4UPLA 3WAYA 4KJGA 1AJDA 4CYSA 1ANIA 2W8SA 3WAWA 1SHNA 2W5WA 2X98A 2RH6A 4UOPA 5IJSA 1ANJA 4GTYA 3NKNA 4GTWA 4GTZA 4YR1A 1ELZA 4UPIA 4TN0A 4LRDA 1ALIA 3M8WA 5EGHA 3DPCA 4LREA 3UNYA 3UO0A 4B56A 4UPKA 5C66A 2W5RA 3B5QA 1HDHA 1P49A 5GOVA 3MK1A 1URBA 2XRGA 4QAXA 5DLWA 2IFYA 3OT9A 1EQJA 4LR9A 5TJ3A 3NKMA 4NWXA 1ELXA 4LRBA 3NKOA 1ED9A 4LR7A 1E3CP 3A52A 1N2LA 4CXSA 5KXAA 4LRAA 4LRFA 1E33P 2ZKTA 3BDFA 3M7VA 2IUCB 3IGZB 1AJAA 4ZG7A 1EW2A 2W5QA 3T02A 5LRNA 3ED4A 1ZEBA 4LQYA 4LR8A 2IUCA 1KHNA 3KD8A 3T01A 2GA3A 2G9YA 3NKRA 2GSOA 1E2SP 3TG0A 1EW8A 2W5TA 1O99A 3LXQA 2XR9A 3NKQA 3NKPA 4GTXA 4KM4A 4MHXA 5LIAA 4LRCA 5L0BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5K4P A;  1EW9 A;  5L0K A;  1E1Z P;  3UN3 A;  2W5V A;  3WBH A;  4UOO A;  1ALJ A;  1K7H A;  1ALK A;  1Y6V A;  4MIV A;  1KH4 A;  3TWZ A;  1HQA A;  4MY4 A;  3SZY A;  2W8D A;  1SHQ A;  3IDD A;  3BDH A;  3SZZ A;  3M8Z A;  4ZGA A;  1EI6 A;  2GSU A;  4FDJ A;  3WAV A;  1URA A;  1N2K A;  5LQQ A;  3Q3Q A;  4NWJ A;  4ZG9 A;  2VQR A;  4KJD A;  1O98 A;  5LRM A;  1AJC A;  5DLV A;  3UN2 A;  3MK2 A;  2GLQ A;  4ZG6 A;  3CMR A;  3T00 A;  1ED8 A;  1KHJ A;  5IJQ A;  2D1G A;  5EGE A;  5INH A;  3WAX A;  5DLT A;  4CYR A;  5AJ9 A;  3TX0 A;  1EJJ A;  1AUK A;  1KH7 A;  3NVL A;  4N7T A;  1ZED A;  2W5S A;  5GRR A;  2GSN A;  3M8Y A;  3IGY B;  5HRT A;  3MK0 A;  1B8J A;  1ELY A;  1KH5 A;  4KAY A;  4CXU A;  2W5X A;  1FSU A;  4UOR A;  5L0E A;  2ANH A;  1KHK A;  3UN5 A;  1KH9 A;  3BDG B;  1ZEF A;  3DYC A;  1KHL A;  4FDI A;  4LR2 A;  1Y7A A;  4UPH A;  1AJB A;  3E2D A;  4CXK A;  4KAV A;  1HJK A;  2QZU A;  3BDG A;  1ALH A;  4UPL A;  3WAY A;  4KJG A;  1AJD A;  4CYS A;  1ANI A;  2W8S A;  3WAW A;  1SHN A;  2W5W A;  2X98 A;  2RH6 A;  4UOP A;  5IJS A;  1ANJ A;  4GTY A;  3NKN A;  4GTW A;  4GTZ A;  4YR1 A;  1ELZ A;  4UPI A;  4TN0 A;  4LRD A;  1ALI A;  3M8W A;  5EGH A;  3DPC A;  4LRE A;  3UNY A;  3UO0 A;  4B56 A;  4UPK A;  5C66 A;  2W5R A;  3B5Q A;  1HDH A;  1P49 A;  5GOV A;  3MK1 A;  1URB A;  2XRG A;  4QAX A;  5DLW A;  2IFY A;  3OT9 A;  1EQJ A;  4LR9 A;  5TJ3 A;  3NKM A;  4NWX A;  1ELX A;  4LRB A;  3NKO A;  1ED9 A;  4LR7 A;  1E3C P;  3A52 A;  1N2L A;  4CXS A;  5KXA A;  4LRA A;  4LRF A;  1E33 P;  2ZKT A;  3BDF A;  3M7V A;  2IUC B;  3IGZ B;  1AJA A;  4ZG7 A;  1EW2 A;  2W5Q A;  3T02 A;  5LRN A;  3ED4 A;  1ZEB A;  4LQY A;  4LR8 A;  2IUC A;  1KHN A;  3KD8 A;  3T01 A;  2GA3 A;  2G9Y A;  3NKR A;  2GSO A;  1E2S P;  3TG0 A;  1EW8 A;  2W5T A;  1O99 A;  3LXQ A;  2XR9 A;  3NKQ A;  3NKP A;  4GTX A;  4KM4 A;  4MHX A;  5LIA A;  4LRC A;  5L0B A; 
#chains in the Genus database with same CATH topology
 5K4P A;  1EW9 A;  5L0K A;  1E1Z P;  3UN3 A;  2W5V A;  3WBH A;  4UOO A;  1ALJ A;  1K7H A;  1ALK A;  1Y6V A;  4MIV A;  1KH4 A;  3TWZ A;  1HQA A;  4MY4 A;  3SZY A;  2W8D A;  1SHQ A;  3IDD A;  3BDH A;  3SZZ A;  3M8Z A;  4ZGA A;  1EI6 A;  2GSU A;  4FDJ A;  3WAV A;  1URA A;  1N2K A;  5LQQ A;  3Q3Q A;  4NWJ A;  4ZG9 A;  2VQR A;  4KJD A;  1O98 A;  5LRM A;  1AJC A;  5DLV A;  3UN2 A;  3MK2 A;  2GLQ A;  4ZG6 A;  3CMR A;  3T00 A;  1ED8 A;  1KHJ A;  5IJQ A;  2D1G A;  5EGE A;  5INH A;  3WAX A;  5DLT A;  4CYR A;  5AJ9 A;  3TX0 A;  1EJJ A;  1AUK A;  1KH7 A;  3NVL A;  4N7T A;  1ZED A;  2W5S A;  5GRR A;  2GSN A;  3M8Y A;  3IGY B;  5HRT A;  3MK0 A;  1B8J A;  1ELY A;  1KH5 A;  4KAY A;  4CXU A;  2W5X A;  1FSU A;  4UOR A;  5L0E A;  2ANH A;  1KHK A;  3UN5 A;  1KH9 A;  3BDG B;  1ZEF A;  3DYC A;  1KHL A;  4FDI A;  4LR2 A;  1Y7A A;  4UPH A;  1AJB A;  3E2D A;  4CXK A;  4KAV A;  1HJK A;  2QZU A;  3BDG A;  1ALH A;  4UPL A;  3WAY A;  4KJG A;  1AJD A;  4CYS A;  1ANI A;  2W8S A;  3WAW A;  1SHN A;  2W5W A;  2X98 A;  2RH6 A;  4UOP A;  5IJS A;  1ANJ A;  4GTY A;  3NKN A;  4GTW A;  4GTZ A;  4YR1 A;  1ELZ A;  4UPI A;  4TN0 A;  4LRD A;  1ALI A;  3M8W A;  5EGH A;  3DPC A;  4LRE A;  3UNY A;  3UO0 A;  4B56 A;  4UPK A;  5C66 A;  2W5R A;  3B5Q A;  1HDH A;  1P49 A;  5GOV A;  3MK1 A;  1URB A;  2XRG A;  4QAX A;  5DLW A;  2IFY A;  3OT9 A;  1EQJ A;  4LR9 A;  5TJ3 A;  3NKM A;  4NWX A;  1ELX A;  4LRB A;  3NKO A;  1ED9 A;  4LR7 A;  1E3C P;  3A52 A;  1N2L A;  4CXS A;  5KXA A;  4LRA A;  4LRF A;  1E33 P;  2ZKT A;  3BDF A;  3M7V A;  2IUC B;  3IGZ B;  1AJA A;  4ZG7 A;  1EW2 A;  2W5Q A;  3T02 A;  5LRN A;  3ED4 A;  1ZEB A;  4LQY A;  4LR8 A;  2IUC A;  1KHN A;  3KD8 A;  3T01 A;  2GA3 A;  2G9Y A;  3NKR A;  2GSO A;  1E2S P;  3TG0 A;  1EW8 A;  2W5T A;  1O99 A;  3LXQ A;  2XR9 A;  3NKQ A;  3NKP A;  4GTX A;  4KM4 A;  4MHX A;  5LIA A;  4LRC A;  5L0B A; 
#chains in the Genus database with same CATH homology
 5K4P A;  1EW9 A;  5L0K A;  1E1Z P;  3UN3 A;  2W5V A;  3WBH A;  4UOO A;  1ALJ A;  1K7H A;  1ALK A;  1Y6V A;  4MIV A;  1KH4 A;  3TWZ A;  1HQA A;  4MY4 A;  3SZY A;  2W8D A;  1SHQ A;  3IDD A;  3BDH A;  3SZZ A;  3M8Z A;  4ZGA A;  1EI6 A;  2GSU A;  4FDJ A;  3WAV A;  1URA A;  1N2K A;  5LQQ A;  3Q3Q A;  4NWJ A;  4ZG9 A;  2VQR A;  4KJD A;  1O98 A;  5LRM A;  1AJC A;  5DLV A;  3UN2 A;  3MK2 A;  2GLQ A;  4ZG6 A;  3CMR A;  3T00 A;  1ED8 A;  1KHJ A;  5IJQ A;  2D1G A;  5EGE A;  5INH A;  3WAX A;  5DLT A;  4CYR A;  5AJ9 A;  3TX0 A;  1EJJ A;  1AUK A;  1KH7 A;  3NVL A;  4N7T A;  1ZED A;  2W5S A;  5GRR A;  2GSN A;  3M8Y A;  3IGY B;  5HRT A;  3MK0 A;  1B8J A;  1ELY A;  1KH5 A;  4KAY A;  4CXU A;  2W5X A;  1FSU A;  4UOR A;  5L0E A;  2ANH A;  1KHK A;  3UN5 A;  1KH9 A;  3BDG B;  1ZEF A;  3DYC A;  1KHL A;  4FDI A;  4LR2 A;  1Y7A A;  4UPH A;  1AJB A;  3E2D A;  4CXK A;  4KAV A;  1HJK A;  2QZU A;  3BDG A;  1ALH A;  4UPL A;  3WAY A;  4KJG A;  1AJD A;  4CYS A;  1ANI A;  2W8S A;  3WAW A;  1SHN A;  2W5W A;  2X98 A;  2RH6 A;  4UOP A;  5IJS A;  1ANJ A;  4GTY A;  3NKN A;  4GTW A;  4GTZ A;  4YR1 A;  1ELZ A;  4UPI A;  4TN0 A;  4LRD A;  1ALI A;  3M8W A;  5EGH A;  3DPC A;  4LRE A;  3UNY A;  3UO0 A;  4B56 A;  4UPK A;  5C66 A;  2W5R A;  3B5Q A;  1HDH A;  1P49 A;  5GOV A;  3MK1 A;  1URB A;  2XRG A;  4QAX A;  5DLW A;  2IFY A;  3OT9 A;  1EQJ A;  4LR9 A;  5TJ3 A;  3NKM A;  4NWX A;  1ELX A;  4LRB A;  3NKO A;  1ED9 A;  4LR7 A;  1E3C P;  3A52 A;  1N2L A;  4CXS A;  5KXA A;  4LRA A;  4LRF A;  1E33 P;  2ZKT A;  3BDF A;  3M7V A;  2IUC B;  3IGZ B;  1AJA A;  4ZG7 A;  1EW2 A;  2W5Q A;  3T02 A;  5LRN A;  3ED4 A;  1ZEB A;  4LQY A;  4LR8 A;  2IUC A;  1KHN A;  3KD8 A;  3T01 A;  2GA3 A;  2G9Y A;  3NKR A;  2GSO A;  1E2S P;  3TG0 A;  1EW8 A;  2W5T A;  1O99 A;  3LXQ A;  2XR9 A;  3NKQ A;  3NKP A;  4GTX A;  4KM4 A;  4MHX A;  5LIA A;  4LRC A;  5L0B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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