3FNMA

Crystal structure of acivicin-inhibited gamma-glutamyltranspeptidase reveals critical roles for its c-terminus in autoprocessing and catalysis
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
342
structure length
342
Chain Sequence
PIKNTKVGLALSSHPLASEIGQKVLEEGGNAIDAAVAIGFALAVVHPAAGNIGGGGFAVIHLANGENVALDFREKAPLKATKNMFLDKQGNVVPKLSEDGYLAAGVPGTVAGMEAMLKKYGTKKLSQLIDPAIKLAENGYAISQRQAETLKEARERFLKYSSSKKYFFKKGHLDYQEGDLFVQKDLAKTLNQIKTLGAKGFYQGQVAELIEKDMKKNGGIITKEDLASYNVKWRKPVVGSYRGYKIISMSPPSSGGTHLIQILNVMENADLSALGYGASKNIHIAAEAMRQAYADRSVYMGDADFVSVPVDKLINKAYAKKIFDTIQPDTVTPSSQIKPGMG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Acivicin-Inhibited gamma-Glutamyltranspeptidase Reveals Critical Roles for Its C-Terminus in Autoprocessing and Catalysis.
pubmed doi rcsb
molecule tags Transferase
source organism Helicobacter pylori
molecule keywords Gamma-glutamyltranspeptidase (Ggt) Large subunit
total genus 109
structure length 342
sequence length 342
chains with identical sequence C
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2008-12-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 3fnmA02
2V36A 4OTUA 2E0XA 4GG2A 4ZBKA 3WHQA 2Z8JA 4ZCGA 3WHRA 2E0YA 3FNMA 4GDXA 2Z8IA 2NQOA 2DBUA 3WHSA 2DG5A 5BPKA 2Z8KA 4OTTA 2QM6A 2DBWA 5B5TA 4Z9OA 2DBXA 4ZC6A 3A75A 2QMCA
chains in the Genus database with same CATH superfamily
2EFDA 3LU8A 2DYOA 1MIWA 1LOTA 3SQJA 2BXAA 1BJ5A 4ZBKA 4F5TA 3W1SA 3SIVB 4ZCGA 4HGMB 2ROHA 2E0YA 2LXTA 3FNMA 1H9ZA 3B9LA 4GDXA 2BXIA 3JRYA 1E7GA 4HGKA 4MBEC 3B9MA 5HOZA 3LU7A 5BPKA 1TXUA 4GDLB 4OTTA 5GINA 2VUEA 4LB9A 1N5UA 1MIYA 3H3AA 2LQIA 2KWFA 1MUHA 1JNBA 2QM6A 3FWCC 1HA2A 4IW1A 1KXPD 3A75A 3KJLA 1IJGA 2OT3A 3GQXA 1GNIA 4F5VA 2BXEA 1E7AA 4D7XA 1HK4A 3CX9A 2AGHB 4K2CA 4OR0A 4ZBRA 5D7GA 2E0XA 3TDLA 2AJEA 4GG2A 3V03A 4FIPB 2I30A 4L8UA 2Z8JA 3WHQA 5GIPA 2EFCA 1VFIA 4WA6B 3UIVA 2XVUA 2EFHA 3WHRA 4FK5B 2KBZA 4BY9C 2CKXA 3VQIA 4BKEA 2XMOA 4F5UA 5IJ5A 2DBUA 3WHSA 4IW2A 2BXGA 4G01A 4OT2A 4LUFA 4DM0A 3A73A 4G04A 5ID9A 2BXCA 3LU6A 1J7EA 2EFEA 1SB0A 3FWBC 4JK4A 1E7FA 3NVIA 2BXFA 4Z9OA 4L9QA 2VUFA 2BXMA 2GUTA 2DYMA 4NAWB 5DQFA 1HK1A 3PLAA 2LXSA 2V36A 2YDFA 1E78A 2XW1A 2JUHA 4LB2A 3NMUA 4ZBQA 4PO0A 1BKEA 5GIOA 4I9OA 1E7BA 5IIHA 1TF0A 4LUHA 1FOUA 2BXBA 3ICXA 3NVKA 3BPJA 1NT2B 2LQHA 2BXNA 1H5WA 5IJEA 4ZUXV 2BX8A 3GA9L 5IFOA 1E7IA 1BM0A 1O9XA 2LOQA 2NNWA 3NVMA 1KDXA 2Z8KA 4TQ1A 2XVQA 4DHXB 2OZBB 1E7CA 4J2VA 5DBYA 5ID7A 2BXHA 4FJCB 4G03A 2DBWA 3MHHB 1E7HA 3V09A 2XW0A 4C31B 2DBXA 3G9KD 5IIUA 4F5SA 4TQ0A 3M99C 1E7EA 3MHSB 4OTUA 4S1YA 3V08A 2XVVA 3ECPA 1HK2A 2XVWA 4N0FD 3H37A 5GHKA 4E99A 2I2ZA 4EMXA 1MM8A 1UORA 2BXOA 2BXLA 1AO6A 1KW2A 1MUSA 2XSIA 2BXQA 2BXDA 1GNJA 1VZSA 2Z8IA 2NQOA 3SIUB 1HK5A 2BXKA 2DG5A 5IJFA 1MIVA 2QHBA 5IIXA 5FUOA 1HK3A 2BXPA 2VDBA 2K0NA 4GDKB 4K71A 4M70B 3JQZA 4N0UD 3GQUA 4LA0A 1LNSA 4L9KA 5B5TA 1J78A 4ZC6A 1MA9A 4W4UB 4N3ZA 3KIKA 4Z69A 2QMCA
chains in the Genus database with same CATH topology
2EFDA 3LU8A 2DYOA 1MIWA 1LOTA 3SQJA 2BXAA 1BJ5A 4ZBKA 4F5TA 3W1SA 3SIVB 4ZCGA 4HGMB 2ROHA 2E0YA 3FNMA 4GDXA 1H9ZA 3B9LA 4HGKA 2BXIA 3JRYA 1E7GA 4MBEC 3B9MA 5HOZA 3LU7A 5BPKA 1TXUA 4GDLB 4OTTA 5GINA 2VUEA 4LB9A 1N5UA 1MIYA 3H3AA 1JNBA 2QM6A 3FWCC 1HA2A 4IW1A 1KXPD 3A75A 3KJLA 1IJGA 2OT3A 3GQXA 1GNIA 4F5VA 2BXEA 1E7AA 1HK4A 3CX9A 4K2CA 4OR0A 4ZBRA 5D7GA 2E0XA 3TDLA 2AJEA 4GG2A 3V03A 4FIPB 2I30A 4L8UA 2Z8JA 3WHQA 5GIPA 2EFCA 1VFIA 4WA6B 3UIVA 2XVUA 2EFHA 3WHRA 4FK5B 2KBZA 4BY9C 2CKXA 3VQIA 4BKEA 2XMOA 4F5UA 5IJ5A 2DBUA 3WHSA 4IW2A 2BXGA 4G01A 4OT2A 4LUFA 3A73A 4G04A 5ID9A 2BXCA 3LU6A 1J7EA 2EFEA 3FWBC 4JK4A 1E7FA 3NVIA 2BXFA 4Z9OA 4L9QA 2VUFA 2BXMA 2DYMA 4NAWB 5DQFA 1HK1A 3PLAA 2V36A 2YDFA 1E78A 2XW1A 2JUHA 4LB2A 3NMUA 4ZBQA 4PO0A 1BKEA 5GIOA 1E7BA 5IIHA 1TF0A 4LUHA 1FOUA 2BXBA 3ICXA 3NVKA 1NT2B 2BXNA 1H5WA 5IJEA 4ZUXV 2BX8A 3GA9L 5IFOA 1E7IA 1BM0A 1O9XA 2LOQA 2NNWA 3NVMA 2Z8KA 4TQ1A 2XVQA 4DHXB 2OZBB 1E7CA 4J2VA 5DBYA 5ID7A 2BXHA 4FJCB 4G03A 2DBWA 3MHHB 1E7HA 3V09A 2XW0A 4C31B 2DBXA 3G9KD 5IIUA 4F5SA 4TQ0A 3M99C 1E7EA 3MHSB 4OTUA 4S1YA 3V08A 2XVVA 1HK2A 2XVWA 4N0FD 3H37A 5GHKA 4E99A 2I2ZA 4EMXA 1UORA 2BXOA 2BXLA 1AO6A 1KW2A 2XSIA 2BXQA 2BXDA 1GNJA 1VZSA 2Z8IA 2NQOA 3SIUB 1HK5A 2BXKA 2DG5A 5IJFA 1MIVA 2QHBA 5IIXA 5FUOA 1HK3A 2BXPA 2VDBA 4GDKB 4K71A 4M70B 3JQZA 4N0UD 3GQUA 4LA0A 1LNSA 4L9KA 5B5TA 1J78A 4ZC6A 1MA9A 4W4UB 4N3ZA 3KIKA 4Z69A 2QMCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V36 A;  4OTU A;  2E0X A;  4GG2 A;  4ZBK A;  3WHQ A;  2Z8J A;  4ZCG A;  3WHR A;  2E0Y A;  3FNM A;  4GDX A;  2Z8I A;  2NQO A;  2DBU A;  3WHS A;  2DG5 A;  5BPK A;  2Z8K A;  4OTT A;  2QM6 A;  2DBW A;  5B5T A;  4Z9O A;  2DBX A;  4ZC6 A;  3A75 A;  2QMC A; 
#chains in the Genus database with same CATH topology
 2EFD A;  3LU8 A;  2DYO A;  1MIW A;  1LOT A;  3SQJ A;  2BXA A;  1BJ5 A;  4ZBK A;  4F5T A;  3W1S A;  3SIV B;  4ZCG A;  4HGM B;  2ROH A;  2E0Y A;  2LXT A;  3FNM A;  1H9Z A;  3B9L A;  4GDX A;  2BXI A;  3JRY A;  1E7G A;  4HGK A;  4MBE C;  3B9M A;  5HOZ A;  3LU7 A;  5BPK A;  1TXU A;  4GDL B;  4OTT A;  5GIN A;  2VUE A;  4LB9 A;  1N5U A;  1MIY A;  3H3A A;  2LQI A;  2KWF A;  1MUH A;  1JNB A;  2QM6 A;  3FWC C;  1HA2 A;  4IW1 A;  1KXP D;  3A75 A;  3KJL A;  1IJG A;  2OT3 A;  3GQX A;  1GNI A;  4F5V A;  2BXE A;  1E7A A;  4D7X A;  1HK4 A;  3CX9 A;  2AGH B;  4K2C A;  4OR0 A;  4ZBR A;  5D7G A;  2E0X A;  3TDL A;  2AJE A;  4GG2 A;  3V03 A;  4FIP B;  2I30 A;  4L8U A;  2Z8J A;  3WHQ A;  5GIP A;  2EFC A;  1VFI A;  4WA6 B;  3UIV A;  2XVU A;  2EFH A;  3WHR A;  4FK5 B;  2KBZ A;  4BY9 C;  2CKX A;  3VQI A;  4BKE A;  2XMO A;  4F5U A;  5IJ5 A;  2DBU A;  3WHS A;  4IW2 A;  2BXG A;  4G01 A;  4OT2 A;  4LUF A;  4DM0 A;  3A73 A;  4G04 A;  5ID9 A;  2BXC A;  3LU6 A;  1J7E A;  2EFE A;  1SB0 A;  3FWB C;  4JK4 A;  1E7F A;  3NVI A;  2BXF A;  4Z9O A;  4L9Q A;  2VUF A;  2BXM A;  2GUT A;  2DYM A;  4NAW B;  5DQF A;  1HK1 A;  3PLA A;  2LXS A;  2V36 A;  2YDF A;  1E78 A;  2XW1 A;  2JUH A;  4LB2 A;  3NMU A;  4ZBQ A;  4PO0 A;  1BKE A;  5GIO A;  4I9O A;  1E7B A;  5IIH A;  1TF0 A;  4LUH A;  1FOU A;  2BXB A;  3ICX A;  3NVK A;  3BPJ A;  1NT2 B;  2LQH A;  2BXN A;  1H5W A;  5IJE A;  4ZUX V;  2BX8 A;  3GA9 L;  5IFO A;  1E7I A;  1BM0 A;  1O9X A;  2LOQ A;  2NNW A;  3NVM A;  1KDX A;  2Z8K A;  4TQ1 A;  2XVQ A;  4DHX B;  2OZB B;  1E7C A;  4J2V A;  5DBY A;  5ID7 A;  2BXH A;  4FJC B;  4G03 A;  2DBW A;  3MHH B;  1E7H A;  3V09 A;  2XW0 A;  4C31 B;  2DBX A;  3G9K D;  5IIU A;  4F5S A;  4TQ0 A;  3M99 C;  1E7E A;  3MHS B;  4OTU A;  4S1Y A;  3V08 A;  2XVV A;  3ECP A;  1HK2 A;  2XVW A;  4N0F D;  3H37 A;  5GHK A;  4E99 A;  2I2Z A;  4EMX A;  1MM8 A;  1UOR A;  2BXO A;  2BXL A;  1AO6 A;  1KW2 A;  1MUS A;  2XSI A;  2BXQ A;  2BXD A;  1GNJ A;  1VZS A;  2Z8I A;  2NQO A;  3SIU B;  1HK5 A;  2BXK A;  2DG5 A;  5IJF A;  1MIV A;  2QHB A;  5IIX A;  5FUO A;  1HK3 A;  2BXP A;  2VDB A;  2K0N A;  4GDK B;  4K71 A;  4M70 B;  3JQZ A;  4N0U D;  3GQU A;  4LA0 A;  1LNS A;  4L9K A;  5B5T A;  1J78 A;  4ZC6 A;  1MA9 A;  4W4U B;  4N3Z A;  3KIK A;  4Z69 A;  2QMC A; 
#chains in the Genus database with same CATH homology
 2EFD A;  3LU8 A;  2DYO A;  1MIW A;  1LOT A;  3SQJ A;  2BXA A;  1BJ5 A;  4ZBK A;  4F5T A;  3W1S A;  3SIV B;  4ZCG A;  4HGM B;  2ROH A;  2E0Y A;  3FNM A;  4GDX A;  1H9Z A;  3B9L A;  4HGK A;  2BXI A;  3JRY A;  1E7G A;  4MBE C;  3B9M A;  5HOZ A;  3LU7 A;  5BPK A;  1TXU A;  4GDL B;  4OTT A;  5GIN A;  2VUE A;  4LB9 A;  1N5U A;  1MIY A;  3H3A A;  1JNB A;  2QM6 A;  3FWC C;  1HA2 A;  4IW1 A;  1KXP D;  3A75 A;  3KJL A;  1IJG A;  2OT3 A;  3GQX A;  1GNI A;  4F5V A;  2BXE A;  1E7A A;  1HK4 A;  3CX9 A;  4K2C A;  4OR0 A;  4ZBR A;  5D7G A;  2E0X A;  3TDL A;  2AJE A;  4GG2 A;  3V03 A;  4FIP B;  2I30 A;  4L8U A;  2Z8J A;  3WHQ A;  5GIP A;  2EFC A;  1VFI A;  4WA6 B;  3UIV A;  2XVU A;  2EFH A;  3WHR A;  4FK5 B;  2KBZ A;  4BY9 C;  2CKX A;  3VQI A;  4BKE A;  2XMO A;  4F5U A;  5IJ5 A;  2DBU A;  3WHS A;  4IW2 A;  2BXG A;  4G01 A;  4OT2 A;  4LUF A;  3A73 A;  4G04 A;  5ID9 A;  2BXC A;  3LU6 A;  1J7E A;  2EFE A;  3FWB C;  4JK4 A;  1E7F A;  3NVI A;  2BXF A;  4Z9O A;  4L9Q A;  2VUF A;  2BXM A;  2DYM A;  4NAW B;  5DQF A;  1HK1 A;  3PLA A;  2V36 A;  2YDF A;  1E78 A;  2XW1 A;  2JUH A;  4LB2 A;  3NMU A;  4ZBQ A;  4PO0 A;  1BKE A;  5GIO A;  1E7B A;  5IIH A;  1TF0 A;  4LUH A;  1FOU A;  2BXB A;  3ICX A;  3NVK A;  1NT2 B;  2BXN A;  1H5W A;  5IJE A;  4ZUX V;  2BX8 A;  3GA9 L;  5IFO A;  1E7I A;  1BM0 A;  1O9X A;  2LOQ A;  2NNW A;  3NVM A;  2Z8K A;  4TQ1 A;  2XVQ A;  4DHX B;  2OZB B;  1E7C A;  4J2V A;  5DBY A;  5ID7 A;  2BXH A;  4FJC B;  4G03 A;  2DBW A;  3MHH B;  1E7H A;  3V09 A;  2XW0 A;  4C31 B;  2DBX A;  3G9K D;  5IIU A;  4F5S A;  4TQ0 A;  3M99 C;  1E7E A;  3MHS B;  4OTU A;  4S1Y A;  3V08 A;  2XVV A;  1HK2 A;  2XVW A;  4N0F D;  3H37 A;  5GHK A;  4E99 A;  2I2Z A;  4EMX A;  1UOR A;  2BXO A;  2BXL A;  1AO6 A;  1KW2 A;  2XSI A;  2BXQ A;  2BXD A;  1GNJ A;  1VZS A;  2Z8I A;  2NQO A;  3SIU B;  1HK5 A;  2BXK A;  2DG5 A;  5IJF A;  1MIV A;  2QHB A;  5IIX A;  5FUO A;  1HK3 A;  2BXP A;  2VDB A;  4GDK B;  4K71 A;  4M70 B;  3JQZ A;  4N0U D;  3GQU A;  4LA0 A;  1LNS A;  4L9K A;  5B5T A;  1J78 A;  4ZC6 A;  1MA9 A;  4W4U B;  4N3Z A;  3KIK A;  4Z69 A;  2QMC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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