3I4ME

8-oxoguanine containing rna polymerase ii elongation complex d
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of transcriptional mutagenesis at 8-oxoguanine
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 50
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3i4mE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3i4mE02
3PO3E 1TWFE 4C3IE 5M3FE 3RZDE 5IYBE 5IYDE 3S17E 4AYBH 1EIKA 5FLME 4A3EE 4A3CE 4Y7NE 1TWAE 4A3LE 2JA8E 3S16E 2JA7E 3GTQE 3HOWE 3GTLE 2Y0SH 3M4OE 2VUME 5IP7E 3H3VF 1R9TE 1I50E 1TWGE 3HOXE 4A3GE 2NVXE 5M5YE 2JA5E 2E2HE 3S14E 4C2ME 2E2JE 2NVTE 2WB1H 5IP9E 2YU9E 3GTKE 3S2HE 2NVYE 4A3FE 2R7ZE 4A3DE 4BBSE 2E2IE 1Y1VE 3S1RE 5M5WE 3PO2E 3M3YE 2B63E 4A3IE 5C4XE 5IYCE 2R92E 3I4NE 3GTME 1Y1WE 3GTGE 4BY1E 3HKZH 3HOZE 2PMZH 4X6AE 4C3JE 5M3ME 1I6HE 3S1NE 3S1QE 1SFOE 4Y52E 3GTJE 3S2DE 3HOVE 4A93E 1TWHE 4A3KE 1DZFA 4A3BE 1K83E 4BXXE 3RZOE 5C3EE 3GTOE 3HOUE 4A3JE 3CQZE 4QIWH 3S15E 3I4ME 3HOYE 2WAQH 1WCME 4A3ME 3FKIE 1I3QE 4C3HE 2JA6E 5M5XE 3K7AE 1TWCE 3GTPE 2NVQE 4BBRE 3S1ME 2R93E 3H0GE 5C44E 5FJ8E 4BY7E 5C4JE
chains in the Genus database with same CATH superfamily
3GTGF 3GTQF 4C3IF 3RZDF 3PO3E 1TWFE 4XSZE 4LJZE 4JK1E 1TWFF 4G7ZE 1R9TF 4C3IE 5M3FE 3RZDE 2WB1I 4YFXE 4G7HE 1YNNK 5IYBE 5IYDE 1SFOF 3S17E 2A6HE 1ZYRE 4YG2E 5M3FF 4Y52F 4AYBH 4A3IF 1EIKA 1I6VE 5IYBF 5FLME 4A3EE 4BBRF 4A3CE 2JA8F 4Y7NE 1TWAE 2NVQF 2R92F 5E17E 4A3LE 2YU9F 4QIWK 4Y7NF 2JA8E 4BY7F 3S16E 2JA7E 5TMFE 4XLPE 3GTQE 4BY1F 3HOWE 3GTLE 2Y0SH 2PPBE 4YFKE 3M4OE 2VUME 2NVXF 3S1MF 5IP7E 5BYHE 2A68E 1I50F 3H3VF 3I4NF 1R9TE 2Y0SI 4LK0E 3HOYF 1I50E 3S15F 1TWGE 3HOXE 2NVYF 4A3GE 2NVXE 3HKZK 1YNJK 3K7AF 4ZH4E 4A3FF 5M5YE 1IW7E 4MEYE 2JA5F 3HOVF 5IPLE 1I3QF 4MEXE 2E2IF 2JA5E 1K83F 4A3BF 3RZOF 2E2HF 3M3YF 1TWAF 1TWCF 2A6EE 2A69E 2E2JF 2E2HE 3HOUF 4XSXE 3GTLF 3S14E 4C2ME 2E2JE 2O5IE 5D4EE 2NVTE 2WB1H 5IP9E 2YU9E 3GTKE 4A3DF 3S2HE 1HQME 2NVYE 4A3FE 1WCMF 3DXJE 5D4DE 4A3MF 4XLNE 4A3JF 2R7ZE 4A3KF 4A3DE 5IP9F 3GTKF 4OIRE 4A3CF 4BBSE 4LK1E 2E2IE 4LLGE 5IYDF 4BXXF 2PMZK 4BBSF 4OIOE 3S1RF 1Y1VE 3S16F 2B63F 1TWHF 3S1RE 4A3GF 5M5WE 3PO2E 4YFNE 3M3YE 2B63E 4A3IE 5IYCF 3M4OF 4A93F 4A3LF 1Y1VF 5C4XE 5IYCE 2R92E 3I4NE 3GTME 5M5XF 5C4JF 2JA7F 3PO2F 4X6AF 5FJ8F 4Q4ZE 3PO3F 1Y1WE 4C2MF 3GTGE 4BY1E 3HKZH 4Q5SE 3H3VG 3HOZE 5C4XF 2PMZH 3S1NF 4X6AE 1SMYE 4KN7E 4C3JE 5M3ME 1I6HE 3S1NE 2R7ZF 3S1QE 3HOZF 4KMUE 4OIQE 1SFOE 4Y52E 2JA6F 4C3HF 3GTJE 3S2DE 3HOVE 5M5YF 4MQ9E 3WODE 4A93E 5M5WF 5TMCE 1TWHE 4A3KE 1DZFA 4A3BE 2R93F 1K83E 4KN4E 3CQZF 4BXXE 3RZOE 4AYBK 5C44F 3HOWF 2BE5E 3S14F 5C3EE 3GTOE 1Y1WF 3HOUE 4A3JE 4G7OE 3CQZE 4GZYE 4QIWH 3S15E 3I4ME 3HOYE 4OIPE 2WAQH 3FKIF 5D4CE 1I6HF 2NVTF 1WCME 4A3ME 5FLMF 4A3EF 3FKIE 3S2HF 1I3QE 3I4MF 4C3HE 5IP7F 3GTOF 3S17F 2JA6E 5E18E 3EQLE 5M5XE 3K7AE 1TWCE 1TWGF 3HOXF 3GTMF 3S1QF 2VUMF 3GTPE 2NVQE 4BBRE 3S1ME 2WAQK 2R93E 3GTPF 2O5JE 4OINE 3GTJF 3S2DF 2CW0E 4C3JF 2KRXA 3H0GE 5M3MF 5C44E 5FJ8E 4BY7E 1QKLA 5C3EF 3H0GF 5C4JE
chains in the Genus database with same CATH topology
3PO3E 1TWFE 4C3IE 5M3FE 3RZDE 5IYBE 5IYDE 3S17E 4AYBH 1EIKA 5FLME 4A3EE 4A3CE 4Y7NE 1TWAE 4A3LE 2JA8E 3S16E 2JA7E 3GTQE 3HOWE 3GTLE 2Y0SH 3M4OE 2VUME 5IP7E 3H3VF 1R9TE 1I50E 1TWGE 3HOXE 4A3GE 2NVXE 5M5YE 2JA5E 2E2HE 3S14E 4C2ME 2E2JE 2NVTE 2WB1H 5IP9E 2YU9E 3GTKE 3S2HE 2NVYE 4A3FE 2R7ZE 4A3DE 4BBSE 2E2IE 1Y1VE 3S1RE 5M5WE 3PO2E 3M3YE 2B63E 4A3IE 5C4XE 5IYCE 2R92E 3I4NE 3GTME 1Y1WE 3GTGE 4BY1E 3HKZH 3HOZE 2PMZH 4X6AE 4C3JE 5M3ME 1I6HE 3S1NE 3S1QE 1SFOE 4Y52E 3GTJE 3S2DE 3HOVE 4A93E 1TWHE 4A3KE 1DZFA 4A3BE 1K83E 4BXXE 3RZOE 5C3EE 3GTOE 3HOUE 4A3JE 3CQZE 4QIWH 3S15E 3I4ME 3HOYE 2WAQH 1WCME 4A3ME 3FKIE 1I3QE 4C3HE 2JA6E 5M5XE 3K7AE 1TWCE 3GTPE 2NVQE 4BBRE 3S1ME 2R93E 3H0GE 5C44E 5FJ8E 4BY7E 5C4JE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PO3 E;  1TWF E;  4C3I E;  5M3F E;  3RZD E;  5IYB E;  5IYD E;  3S17 E;  4AYB H;  1EIK A;  5FLM E;  4A3E E;  4A3C E;  4Y7N E;  1TWA E;  4A3L E;  2JA8 E;  3S16 E;  2JA7 E;  3GTQ E;  3HOW E;  3GTL E;  2Y0S H;  3M4O E;  2VUM E;  5IP7 E;  3H3V F;  1R9T E;  1I50 E;  1TWG E;  3HOX E;  4A3G E;  2NVX E;  5M5Y E;  2JA5 E;  2E2H E;  3S14 E;  4C2M E;  2E2J E;  2NVT E;  2WB1 H;  5IP9 E;  2YU9 E;  3GTK E;  3S2H E;  2NVY E;  4A3F E;  2R7Z E;  4A3D E;  4BBS E;  2E2I E;  1Y1V E;  3S1R E;  5M5W E;  3PO2 E;  3M3Y E;  2B63 E;  4A3I E;  5C4X E;  5IYC E;  2R92 E;  3I4N E;  3GTM E;  1Y1W E;  3GTG E;  4BY1 E;  3HKZ H;  3HOZ E;  2PMZ H;  4X6A E;  4C3J E;  5M3M E;  1I6H E;  3S1N E;  3S1Q E;  1SFO E;  4Y52 E;  3GTJ E;  3S2D E;  3HOV E;  4A93 E;  1TWH E;  4A3K E;  1DZF A;  4A3B E;  1K83 E;  4BXX E;  3RZO E;  5C3E E;  3GTO E;  3HOU E;  4A3J E;  3CQZ E;  4QIW H;  3S15 E;  3I4M E;  3HOY E;  2WAQ H;  1WCM E;  4A3M E;  3FKI E;  1I3Q E;  4C3H E;  2JA6 E;  5M5X E;  3K7A E;  1TWC E;  3GTP E;  2NVQ E;  4BBR E;  3S1M E;  2R93 E;  3H0G E;  5C44 E;  5FJ8 E;  4BY7 E;  5C4J E; 
#chains in the Genus database with same CATH topology
 3GTG F;  3GTQ F;  4C3I F;  3RZD F;  3PO3 E;  1TWF E;  4XSZ E;  4LJZ E;  4JK1 E;  1TWF F;  4G7Z E;  1R9T F;  4C3I E;  5M3F E;  3RZD E;  2WB1 I;  4YFX E;  4G7H E;  1YNN K;  5IYB E;  5IYD E;  1SFO F;  3S17 E;  2A6H E;  1ZYR E;  4YG2 E;  5M3F F;  4Y52 F;  4AYB H;  4A3I F;  1EIK A;  1I6V E;  5IYB F;  5FLM E;  4A3E E;  4BBR F;  4A3C E;  2JA8 F;  4Y7N E;  1TWA E;  2NVQ F;  2R92 F;  5E17 E;  4A3L E;  2YU9 F;  4QIW K;  4Y7N F;  2JA8 E;  4BY7 F;  3S16 E;  2JA7 E;  5TMF E;  4XLP E;  3GTQ E;  4BY1 F;  3HOW E;  3GTL E;  2Y0S H;  2PPB E;  4YFK E;  3M4O E;  2VUM E;  2NVX F;  3S1M F;  5IP7 E;  5BYH E;  2A68 E;  1I50 F;  3H3V F;  3I4N F;  1R9T E;  2Y0S I;  4LK0 E;  3HOY F;  1I50 E;  3S15 F;  1TWG E;  3HOX E;  2NVY F;  4A3G E;  2NVX E;  3HKZ K;  1YNJ K;  3K7A F;  4ZH4 E;  4A3F F;  5M5Y E;  1IW7 E;  4MEY E;  2JA5 F;  3HOV F;  5IPL E;  1I3Q F;  4MEX E;  2E2I F;  2JA5 E;  1K83 F;  4A3B F;  3RZO F;  2E2H F;  3M3Y F;  1TWA F;  1TWC F;  2A6E E;  2A69 E;  2E2J F;  2E2H E;  3HOU F;  4XSX E;  3GTL F;  3S14 E;  4C2M E;  2E2J E;  2O5I E;  5D4E E;  2NVT E;  2WB1 H;  5IP9 E;  2YU9 E;  3GTK E;  4A3D F;  3S2H E;  1HQM E;  2NVY E;  4A3F E;  1WCM F;  3DXJ E;  5D4D E;  4A3M F;  4XLN E;  4A3J F;  2R7Z E;  4A3K F;  4A3D E;  5IP9 F;  3GTK F;  4OIR E;  4A3C F;  4BBS E;  4LK1 E;  2E2I E;  4LLG E;  5IYD F;  4BXX F;  2PMZ K;  4BBS F;  4OIO E;  3S1R F;  1Y1V E;  3S16 F;  2B63 F;  1TWH F;  3S1R E;  4A3G F;  5M5W E;  3PO2 E;  4YFN E;  3M3Y E;  2B63 E;  4A3I E;  5IYC F;  3M4O F;  4A93 F;  4A3L F;  1Y1V F;  5C4X E;  5IYC E;  2R92 E;  3I4N E;  3GTM E;  5M5X F;  5C4J F;  2JA7 F;  3PO2 F;  4X6A F;  5FJ8 F;  4Q4Z E;  3PO3 F;  1Y1W E;  4C2M F;  3GTG E;  4BY1 E;  3HKZ H;  4Q5S E;  3H3V G;  3HOZ E;  5C4X F;  2PMZ H;  3S1N F;  4X6A E;  1SMY E;  4KN7 E;  4C3J E;  5M3M E;  1I6H E;  3S1N E;  2R7Z F;  3S1Q E;  3HOZ F;  4KMU E;  4OIQ E;  1SFO E;  4Y52 E;  2JA6 F;  4C3H F;  3GTJ E;  3S2D E;  3HOV E;  5M5Y F;  4MQ9 E;  3WOD E;  4A93 E;  5M5W F;  5TMC E;  1TWH E;  4A3K E;  1DZF A;  4A3B E;  2R93 F;  1K83 E;  4KN4 E;  3CQZ F;  4BXX E;  3RZO E;  4AYB K;  5C44 F;  3HOW F;  2BE5 E;  3S14 F;  5C3E E;  3GTO E;  1Y1W F;  3HOU E;  4A3J E;  4G7O E;  3CQZ E;  4GZY E;  4QIW H;  3S15 E;  3I4M E;  3HOY E;  4OIP E;  2WAQ H;  3FKI F;  5D4C E;  1I6H F;  2NVT F;  1WCM E;  4A3M E;  5FLM F;  4A3E F;  3FKI E;  3S2H F;  1I3Q E;  3I4M F;  4C3H E;  5IP7 F;  3GTO F;  3S17 F;  2JA6 E;  5E18 E;  3EQL E;  5M5X E;  3K7A E;  1TWC E;  1TWG F;  3HOX F;  3GTM F;  3S1Q F;  2VUM F;  3GTP E;  2NVQ E;  4BBR E;  3S1M E;  2WAQ K;  2R93 E;  3GTP F;  2O5J E;  4OIN E;  3GTJ F;  3S2D F;  2CW0 E;  4C3J F;  2KRX A;  3H0G E;  5M3M F;  5C44 E;  5FJ8 E;  4BY7 E;  1QKL A;  5C3E F;  3H0G F;  5C4J E; 
#chains in the Genus database with same CATH homology
 3PO3 E;  1TWF E;  4C3I E;  5M3F E;  3RZD E;  5IYB E;  5IYD E;  3S17 E;  4AYB H;  1EIK A;  5FLM E;  4A3E E;  4A3C E;  4Y7N E;  1TWA E;  4A3L E;  2JA8 E;  3S16 E;  2JA7 E;  3GTQ E;  3HOW E;  3GTL E;  2Y0S H;  3M4O E;  2VUM E;  5IP7 E;  3H3V F;  1R9T E;  1I50 E;  1TWG E;  3HOX E;  4A3G E;  2NVX E;  5M5Y E;  2JA5 E;  2E2H E;  3S14 E;  4C2M E;  2E2J E;  2NVT E;  2WB1 H;  5IP9 E;  2YU9 E;  3GTK E;  3S2H E;  2NVY E;  4A3F E;  2R7Z E;  4A3D E;  4BBS E;  2E2I E;  1Y1V E;  3S1R E;  5M5W E;  3PO2 E;  3M3Y E;  2B63 E;  4A3I E;  5C4X E;  5IYC E;  2R92 E;  3I4N E;  3GTM E;  1Y1W E;  3GTG E;  4BY1 E;  3HKZ H;  3HOZ E;  2PMZ H;  4X6A E;  4C3J E;  5M3M E;  1I6H E;  3S1N E;  3S1Q E;  1SFO E;  4Y52 E;  3GTJ E;  3S2D E;  3HOV E;  4A93 E;  1TWH E;  4A3K E;  1DZF A;  4A3B E;  1K83 E;  4BXX E;  3RZO E;  5C3E E;  3GTO E;  3HOU E;  4A3J E;  3CQZ E;  4QIW H;  3S15 E;  3I4M E;  3HOY E;  2WAQ H;  1WCM E;  4A3M E;  3FKI E;  1I3Q E;  4C3H E;  2JA6 E;  5M5X E;  3K7A E;  1TWC E;  3GTP E;  2NVQ E;  4BBR E;  3S1M E;  2R93 E;  3H0G E;  5C44 E;  5FJ8 E;  4BY7 E;  5C4J E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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