3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
1R5GA 2BHAA 2BHCA 3MR1A 4FLJA 2ADUA 2Q93A 3CB6A 4U6JA 4QR8A 2ZSGA 2EA2A 4U73A 2GG9A 3PKEA 2P9AA 1BOAA 1WKMA 2OAZA 2GG8A 4IDYA 2B3HA 4ZNGA 3S6BA 1WN1A 3IG4A 1C21A 4S2TP 4FLKA 4ZWUA 2NQ7A 1M35A 1KQ0A 2V3XA 4EGEA 2MATA 2IW2A 2V3YA 4PNCA 4RGZ1 4IKRA 2GZ5A 4FKCA 1C22A 4U75A 2B3LA 3MX6A 2HOWA 2P99A 3TB5A 1MATA 3FM3A 5FCFA 5FCHA 1YW9A 2EVMA 4FUKA 1A16A 1QZYA 4FLIA 5CLSA 3BITA 4U69A 5JI6A 1Y1NA 2BN7A 3TAVA 5JHUA 2BWTA 2EA4A 3IU8A 2GG7A 4IF7A 4MATA 3MATA 2GU7A 3D27A 2NQ6A 4Z7MA 2V6CA 5CNXA 3CB5A 5CDVA 1O0XA 5CDLA 4U71A 2Q92A 2GG0A 2GGCA 1B6AA 2BWVA 2G6PA 2GA2A 3PKBA 4IU6A 4U1BA 4S2RP 1WLRA 2Q94A 3L7GA 3Q6DA 2EVCA 2EVOA 3CTZA 3FMQA 1YW7A 2GG3A 1C23A 1R5HA 2BWWA 2BWYA 2GG2A 1W2MA 3BIQA 2GU5A 5CDEA 1XGNA 5CIKA 2B3KA 2BB7A 1WL6A 2Q8KA 1KQ9A 1YVMA 4U76A 1XGSA 3IU9A 4U6WA 1BN5A 4OOKA 2V3ZA 2GU6A 1C24A 4B28A 1W7VA 2BH3A 4ZWOA 3RORA 3RVAA 1R58A 2GU4A 1XGOA 1YW8A 1KP0A 4U6ZA 1N51A 1XGMA 2GTXA 5D6EA 1XNZA 4KM3A 4A6VA 4IPAA 2P98A 2GG5A 5E5BA 2BHBA 2DFIA 4RZZA 4IECA 3PKAA 3FMRA 5JFRA 4IKTA 1WBQA 1PV9A 4IKUA 4FO8A 3PKDA 4A6WA 4HXXA 1QXWA 1WL9A 4FLLA 4IKSA 1JAWA 1CHMA 1QXZA 4S00A 4RZYA 4S01A 2Q95A 2BWSA 1B59A 2OKNA 4U70A 2Q96A 4FO7A 1QXYA 3IU7A 4PV4A 4U6EA 1YJ3A 2GGBA 3BIPA 4ZWPA 4JUQA 3L24A 5D6FA 2BWUA 2BWXA 2BHDA 3PKCA 5CE6A 1C27A 1WY2A 4U6CA 4R60A
chains in the Genus database with same CATH superfamily
1R5GA 2BHAA 2BHCA 3MR1A 4FLJA 2ADUA 2Q93A 3CB6A 4U6JA 4QR8A 2ZSGA 2EA2A 4U73A 2GG9A 3PKEA 2P9AA 1BOAA 1WKMA 2OAZA 2GG8A 4IDYA 2B3HA 4ZNGA 3S6BA 1WN1A 3IG4A 1C21A 4S2TP 4FLKA 4ZWUA 2NQ7A 1M35A 1KQ0A 2V3XA 4EGEA 2MATA 2IW2A 2V3YA 4PNCA 4RGZ1 4IKRA 2GZ5A 4FKCA 1C22A 4U75A 2B3LA 3MX6A 2HOWA 2P99A 3TB5A 1MATA 3FM3A 5FCFA 5FCHA 1YW9A 2EVMA 4FUKA 1A16A 1QZYA 4FLIA 5CLSA 3BITA 4U69A 5JI6A 1Y1NA 2BN7A 3TAVA 5JHUA 2BWTA 2EA4A 3IU8A 2GG7A 4IF7A 4MATA 3MATA 2GU7A 3D27A 2NQ6A 4Z7MA 2V6CA 5CNXA 3CB5A 5CDVA 1O0XA 5CDLA 4U71A 2Q92A 2GG0A 2GGCA 1B6AA 2BWVA 2G6PA 2GA2A 3PKBA 4IU6A 4U1BA 4S2RP 1WLRA 2Q94A 3L7GA 3Q6DA 2EVCA 2EVOA 3CTZA 3FMQA 1YW7A 2GG3A 1C23A 1R5HA 2BWWA 2BWYA 2GG2A 1W2MA 3BIQA 2GU5A 5CDEA 1XGNA 5CIKA 2B3KA 2BB7A 1WL6A 2Q8KA 1KQ9A 1YVMA 4U76A 1XGSA 3IU9A 4U6WA 1BN5A 4OOKA 2V3ZA 2GU6A 1C24A 4B28A 1W7VA 2BH3A 4ZWOA 3RORA 3RVAA 1R58A 2GU4A 1XGOA 1YW8A 1KP0A 4U6ZA 1N51A 1XGMA 2GTXA 5D6EA 1XNZA 4KM3A 4A6VA 4IPAA 2P98A 2GG5A 5E5BA 2BHBA 2DFIA 4RZZA 4IECA 3PKAA 3FMRA 5JFRA 4IKTA 1WBQA 1PV9A 4IKUA 4FO8A 3PKDA 4A6WA 4HXXA 1QXWA 1WL9A 4FLLA 4IKSA 1JAWA 1CHMA 1QXZA 4S00A 4RZYA 4S01A 2Q95A 2BWSA 1B59A 2OKNA 4U70A 2Q96A 4FO7A 1QXYA 3IU7A 4PV4A 4U6EA 1YJ3A 2GGBA 3BIPA 4ZWPA 4JUQA 3L24A 5D6FA 2BWUA 2BWXA 2BHDA 3PKCA 5CE6A 1C27A 1WY2A 4U6CA 4R60A
chains in the Genus database with same CATH topology
1R5GA 2BHAA 2BHCA 3MR1A 4FLJA 2ADUA 2Q93A 3CB6A 4U6JA 4QR8A 2ZSGA 2EA2A 4U73A 2GG9A 3PKEA 2P9AA 1BOAA 1WKMA 2OAZA 2GG8A 4IDYA 2B3HA 4ZNGA 3S6BA 1WN1A 3IG4A 1C21A 4S2TP 4FLKA 4ZWUA 2NQ7A 1M35A 1KQ0A 2V3XA 4EGEA 2MATA 2IW2A 2V3YA 4PNCA 4RGZ1 4IKRA 2GZ5A 4FKCA 1C22A 4U75A 2B3LA 3MX6A 2HOWA 2P99A 3TB5A 1MATA 3FM3A 5FCFA 5FCHA 1YW9A 2EVMA 4FUKA 1A16A 1QZYA 4FLIA 5CLSA 3BITA 4U69A 5JI6A 1Y1NA 2BN7A 3TAVA 5JHUA 2BWTA 2EA4A 3IU8A 2GG7A 4IF7A 4MATA 3MATA 2GU7A 3D27A 2NQ6A 4Z7MA 2V6CA 5CNXA 3CB5A 5CDVA 1O0XA 5CDLA 4U71A 2Q92A 2GG0A 2GGCA 1B6AA 2BWVA 2G6PA 2GA2A 3PKBA 4IU6A 4U1BA 4S2RP 1WLRA 2Q94A 3L7GA 3Q6DA 2EVCA 2EVOA 3CTZA 3FMQA 1YW7A 2GG3A 1C23A 1R5HA 2BWWA 2BWYA 2GG2A 1W2MA 3BIQA 2GU5A 5CDEA 1XGNA 5CIKA 2B3KA 2BB7A 1WL6A 2Q8KA 1KQ9A 1YVMA 4U76A 1XGSA 3IU9A 4U6WA 1BN5A 4OOKA 2V3ZA 2GU6A 1C24A 4B28A 1W7VA 2BH3A 4ZWOA 3RORA 3RVAA 1R58A 2GU4A 1XGOA 1YW8A 1KP0A 4U6ZA 1N51A 1XGMA 2GTXA 5D6EA 1XNZA 4KM3A 4A6VA 4IPAA 2P98A 2GG5A 5E5BA 2BHBA 2DFIA 4RZZA 4IECA 3PKAA 3FMRA 5JFRA 4IKTA 1WBQA 1PV9A 4IKUA 4FO8A 3PKDA 4A6WA 4HXXA 1QXWA 1WL9A 4FLLA 4IKSA 1JAWA 1CHMA 1QXZA 4S00A 4RZYA 4S01A 2Q95A 2BWSA 1B59A 2OKNA 4U70A 2Q96A 4FO7A 1QXYA 3IU7A 4PV4A 4U6EA 1YJ3A 2GGBA 3BIPA 4ZWPA 4JUQA 3L24A 5D6FA 2BWUA 2BWXA 2BHDA 3PKCA 5CE6A 1C27A 1WY2A 4U6CA 4R60A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R5G A;  2BHA A;  2BHC A;  3MR1 A;  4FLJ A;  2ADU A;  2Q93 A;  3CB6 A;  4U6J A;  4QR8 A;  2ZSG A;  2EA2 A;  4U73 A;  2GG9 A;  3PKE A;  2P9A A;  1BOA A;  1WKM A;  2OAZ A;  2GG8 A;  4IDY A;  2B3H A;  4ZNG A;  3S6B A;  1WN1 A;  3IG4 A;  1C21 A;  4S2T P;  4FLK A;  4ZWU A;  2NQ7 A;  1M35 A;  1KQ0 A;  2V3X A;  4EGE A;  2MAT A;  2IW2 A;  2V3Y A;  4PNC A;  4RGZ 1;  4IKR A;  2GZ5 A;  4FKC A;  1C22 A;  4U75 A;  2B3L A;  3MX6 A;  2HOW A;  2P99 A;  3TB5 A;  1MAT A;  3FM3 A;  5FCF A;  5FCH A;  1YW9 A;  2EVM A;  4FUK A;  1A16 A;  1QZY A;  4FLI A;  5CLS A;  3BIT A;  4U69 A;  5JI6 A;  1Y1N A;  2BN7 A;  3TAV A;  5JHU A;  2BWT A;  2EA4 A;  3IU8 A;  2GG7 A;  4IF7 A;  4MAT A;  3MAT A;  2GU7 A;  3D27 A;  2NQ6 A;  4Z7M A;  2V6C A;  5CNX A;  3CB5 A;  5CDV A;  1O0X A;  5CDL A;  4U71 A;  2Q92 A;  2GG0 A;  2GGC A;  1B6A A;  2BWV A;  2G6P A;  2GA2 A;  3PKB A;  4IU6 A;  4U1B A;  4S2R P;  1WLR A;  2Q94 A;  3L7G A;  3Q6D A;  2EVC A;  2EVO A;  3CTZ A;  3FMQ A;  1YW7 A;  2GG3 A;  1C23 A;  1R5H A;  2BWW A;  2BWY A;  2GG2 A;  1W2M A;  3BIQ A;  2GU5 A;  5CDE A;  1XGN A;  5CIK A;  2B3K A;  2BB7 A;  1WL6 A;  2Q8K A;  1KQ9 A;  1YVM A;  4U76 A;  1XGS A;  3IU9 A;  4U6W A;  1BN5 A;  4OOK A;  2V3Z A;  2GU6 A;  1C24 A;  4B28 A;  1W7V A;  2BH3 A;  4ZWO A;  3ROR A;  3RVA A;  1R58 A;  2GU4 A;  1XGO A;  1YW8 A;  1KP0 A;  4U6Z A;  1N51 A;  1XGM A;  2GTX A;  5D6E A;  1XNZ A;  4KM3 A;  4A6V A;  4IPA A;  2P98 A;  2GG5 A;  5E5B A;  2BHB A;  2DFI A;  4RZZ A;  4IEC A;  3PKA A;  3FMR A;  5JFR A;  4IKT A;  1WBQ A;  1PV9 A;  4IKU A;  4FO8 A;  3PKD A;  4A6W A;  4HXX A;  1QXW A;  1WL9 A;  4FLL A;  4IKS A;  1JAW A;  1CHM A;  1QXZ A;  4S00 A;  4RZY A;  4S01 A;  2Q95 A;  2BWS A;  1B59 A;  2OKN A;  4U70 A;  2Q96 A;  4FO7 A;  1QXY A;  3IU7 A;  4PV4 A;  4U6E A;  1YJ3 A;  2GGB A;  3BIP A;  4ZWP A;  4JUQ A;  3L24 A;  5D6F A;  2BWU A;  2BWX A;  2BHD A;  3PKC A;  5CE6 A;  1C27 A;  1WY2 A;  4U6C A;  4R60 A; 
#chains in the Genus database with same CATH topology
 1R5G A;  2BHA A;  2BHC A;  3MR1 A;  4FLJ A;  2ADU A;  2Q93 A;  3CB6 A;  4U6J A;  4QR8 A;  2ZSG A;  2EA2 A;  4U73 A;  2GG9 A;  3PKE A;  2P9A A;  1BOA A;  1WKM A;  2OAZ A;  2GG8 A;  4IDY A;  2B3H A;  4ZNG A;  3S6B A;  1WN1 A;  3IG4 A;  1C21 A;  4S2T P;  4FLK A;  4ZWU A;  2NQ7 A;  1M35 A;  1KQ0 A;  2V3X A;  4EGE A;  2MAT A;  2IW2 A;  2V3Y A;  4PNC A;  4RGZ 1;  4IKR A;  2GZ5 A;  4FKC A;  1C22 A;  4U75 A;  2B3L A;  3MX6 A;  2HOW A;  2P99 A;  3TB5 A;  1MAT A;  3FM3 A;  5FCF A;  5FCH A;  1YW9 A;  2EVM A;  4FUK A;  1A16 A;  1QZY A;  4FLI A;  5CLS A;  3BIT A;  4U69 A;  5JI6 A;  1Y1N A;  2BN7 A;  3TAV A;  5JHU A;  2BWT A;  2EA4 A;  3IU8 A;  2GG7 A;  4IF7 A;  4MAT A;  3MAT A;  2GU7 A;  3D27 A;  2NQ6 A;  4Z7M A;  2V6C A;  5CNX A;  3CB5 A;  5CDV A;  1O0X A;  5CDL A;  4U71 A;  2Q92 A;  2GG0 A;  2GGC A;  1B6A A;  2BWV A;  2G6P A;  2GA2 A;  3PKB A;  4IU6 A;  4U1B A;  4S2R P;  1WLR A;  2Q94 A;  3L7G A;  3Q6D A;  2EVC A;  2EVO A;  3CTZ A;  3FMQ A;  1YW7 A;  2GG3 A;  1C23 A;  1R5H A;  2BWW A;  2BWY A;  2GG2 A;  1W2M A;  3BIQ A;  2GU5 A;  5CDE A;  1XGN A;  5CIK A;  2B3K A;  2BB7 A;  1WL6 A;  2Q8K A;  1KQ9 A;  1YVM A;  4U76 A;  1XGS A;  3IU9 A;  4U6W A;  1BN5 A;  4OOK A;  2V3Z A;  2GU6 A;  1C24 A;  4B28 A;  1W7V A;  2BH3 A;  4ZWO A;  3ROR A;  3RVA A;  1R58 A;  2GU4 A;  1XGO A;  1YW8 A;  1KP0 A;  4U6Z A;  1N51 A;  1XGM A;  2GTX A;  5D6E A;  1XNZ A;  4KM3 A;  4A6V A;  4IPA A;  2P98 A;  2GG5 A;  5E5B A;  2BHB A;  2DFI A;  4RZZ A;  4IEC A;  3PKA A;  3FMR A;  5JFR A;  4IKT A;  1WBQ A;  1PV9 A;  4IKU A;  4FO8 A;  3PKD A;  4A6W A;  4HXX A;  1QXW A;  1WL9 A;  4FLL A;  4IKS A;  1JAW A;  1CHM A;  1QXZ A;  4S00 A;  4RZY A;  4S01 A;  2Q95 A;  2BWS A;  1B59 A;  2OKN A;  4U70 A;  2Q96 A;  4FO7 A;  1QXY A;  3IU7 A;  4PV4 A;  4U6E A;  1YJ3 A;  2GGB A;  3BIP A;  4ZWP A;  4JUQ A;  3L24 A;  5D6F A;  2BWU A;  2BWX A;  2BHD A;  3PKC A;  5CE6 A;  1C27 A;  1WY2 A;  4U6C A;  4R60 A; 
#chains in the Genus database with same CATH homology
 1R5G A;  2BHA A;  2BHC A;  3MR1 A;  4FLJ A;  2ADU A;  2Q93 A;  3CB6 A;  4U6J A;  4QR8 A;  2ZSG A;  2EA2 A;  4U73 A;  2GG9 A;  3PKE A;  2P9A A;  1BOA A;  1WKM A;  2OAZ A;  2GG8 A;  4IDY A;  2B3H A;  4ZNG A;  3S6B A;  1WN1 A;  3IG4 A;  1C21 A;  4S2T P;  4FLK A;  4ZWU A;  2NQ7 A;  1M35 A;  1KQ0 A;  2V3X A;  4EGE A;  2MAT A;  2IW2 A;  2V3Y A;  4PNC A;  4RGZ 1;  4IKR A;  2GZ5 A;  4FKC A;  1C22 A;  4U75 A;  2B3L A;  3MX6 A;  2HOW A;  2P99 A;  3TB5 A;  1MAT A;  3FM3 A;  5FCF A;  5FCH A;  1YW9 A;  2EVM A;  4FUK A;  1A16 A;  1QZY A;  4FLI A;  5CLS A;  3BIT A;  4U69 A;  5JI6 A;  1Y1N A;  2BN7 A;  3TAV A;  5JHU A;  2BWT A;  2EA4 A;  3IU8 A;  2GG7 A;  4IF7 A;  4MAT A;  3MAT A;  2GU7 A;  3D27 A;  2NQ6 A;  4Z7M A;  2V6C A;  5CNX A;  3CB5 A;  5CDV A;  1O0X A;  5CDL A;  4U71 A;  2Q92 A;  2GG0 A;  2GGC A;  1B6A A;  2BWV A;  2G6P A;  2GA2 A;  3PKB A;  4IU6 A;  4U1B A;  4S2R P;  1WLR A;  2Q94 A;  3L7G A;  3Q6D A;  2EVC A;  2EVO A;  3CTZ A;  3FMQ A;  1YW7 A;  2GG3 A;  1C23 A;  1R5H A;  2BWW A;  2BWY A;  2GG2 A;  1W2M A;  3BIQ A;  2GU5 A;  5CDE A;  1XGN A;  5CIK A;  2B3K A;  2BB7 A;  1WL6 A;  2Q8K A;  1KQ9 A;  1YVM A;  4U76 A;  1XGS A;  3IU9 A;  4U6W A;  1BN5 A;  4OOK A;  2V3Z A;  2GU6 A;  1C24 A;  4B28 A;  1W7V A;  2BH3 A;  4ZWO A;  3ROR A;  3RVA A;  1R58 A;  2GU4 A;  1XGO A;  1YW8 A;  1KP0 A;  4U6Z A;  1N51 A;  1XGM A;  2GTX A;  5D6E A;  1XNZ A;  4KM3 A;  4A6V A;  4IPA A;  2P98 A;  2GG5 A;  5E5B A;  2BHB A;  2DFI A;  4RZZ A;  4IEC A;  3PKA A;  3FMR A;  5JFR A;  4IKT A;  1WBQ A;  1PV9 A;  4IKU A;  4FO8 A;  3PKD A;  4A6W A;  4HXX A;  1QXW A;  1WL9 A;  4FLL A;  4IKS A;  1JAW A;  1CHM A;  1QXZ A;  4S00 A;  4RZY A;  4S01 A;  2Q95 A;  2BWS A;  1B59 A;  2OKN A;  4U70 A;  2Q96 A;  4FO7 A;  1QXY A;  3IU7 A;  4PV4 A;  4U6E A;  1YJ3 A;  2GGB A;  3BIP A;  4ZWP A;  4JUQ A;  3L24 A;  5D6F A;  2BWU A;  2BWX A;  2BHD A;  3PKC A;  5CE6 A;  1C27 A;  1WY2 A;  4U6C A;  4R60 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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