3JYFA

The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from klebsiella pneumoniae subsp. pneumoniae mgh 78578
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
336
structure length
336
Chain Sequence
AATVDLRIMETTDLHSNMMDFDYYKDAATEKFGLVRTASLIEQARAEVKNSVLVDNGDVIQGSPLGDYMAAKGLKEGDVHPVYKAMNTLNYAVGNLGNHEFNYGLDFLHKALAGAKFPYVNANIIDAKTGKPMFTPYLIQDTRVVDSDGQIHTLRIGYIGFVPPQIMTWDKANLNGKVTVNDITETARKYIPEMRAKGADVVVVVAHSGLSADPYQAMAENSVYYLSQVPGVDAIMFGHAHAVFPGKDFANIKGADIAKGTLNGVPAVMPGMWGDHLGVVDLVLNNDSGKWQVTQSKAEARPIYDAVAKKSLAAEDGKLVSVLKADHDATREFVSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of a 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from Klebsiella pneumoniae subsp. pneumoniae MGH 78578
rcsb
molecule tags Hydrolase
source organism Klebsiella pneumoniae subsp. pneumoniae
molecule keywords 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase
total genus 91
structure length 336
sequence length 336
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-09-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3jyfA00
1QHWA 2BDXA 4WWLA 4UT2A 3V4YA 1S3MA 3T1IA 4O43A 3P71C 1T70A 2GJUA 3C5WC 2AHDA 2O8AA 2HYPA 4KBPA 3QFKA 4ORCA 4Q7FA 1AUIA 2O8GA 2NPPC 2ZBMA 3AUZA 4O4KA 2JOGA 5HPEA 1IT6A 3PSOA 1FJMA 3H69A 1XZWA 4ZVZA 2KKNA 2HYOA 1JK7A 1OIDA 4FBWA 4ORBA 2CV9A 1S3NA 4F0ZA 2IE4C 3EGGA 5JJTA 2QFPA 4JA7A 3H62B 3ICFA 4H1YP 4ZX2A 5JPEA 1Z2XA 3RL3A 5INBA 2BQ8X 1SU1A 4MP0A 2WDDA 1M63A 4H1SA 5J28A 4H2IA 3RL4A 4V0XA 4HD0A 4V0WA 2NYLC 4NZVA 1V73A 1HPUA 2Q8UA 3H66A 1U32A 3DSCA 4FBQA 2P6BA 1II7A 1NNWA 3E7AA 3KBPA 3QFOA 4IYPC 2QFRA 1OI8A 1T71A 4YKEA 5GTUA 3IB8A 2NXFA 3ZU0A 1S95A 4B2OA 1HO5A 4TUGA 2WDFA 3LL8A 2XMOA 3AV0A 1G5BA 2HY1A 2Z1AA 4ORAA 4M0VA 3RQZA 4I5NC 5JPFA 2Z06A 4H2GA 4V0VA 3H61A 1UF3A 3TGHA 4H2BA 4FCXA 3H64A 2USHA 3QFNA 4KKZA 4O5GA 2YVTA 4I5LC 1OIEA 3C9FA 3H60A 5EQVA 4MOVA 5IOHA 3K7VC 3FGAC 3THOB 2WDCA 2IE3C 5DNYA 4O24A 1TCOA 3H68A 3EGHA 3QG5C 1UTEA 3RL5A 1W24A 4LTYA 1WARA 4MOYA 3THNA 3ZTVA 1S8EA 3N5UA 1Z2WA 4XPNA 4JA9A 4LACC 4J6OA 2BCDA 4OR9A 1WAO1 2IAEC 1S3LA 3DSDA 1XM7A 3H63A 2A22A 4DT2A 2DFJA 4IL1A 1QFCA 3K7WC 5C1VA 3GVEA 4UT3A 2WDEA 1HP1A 4DSYA 2NYMC 5F3WA 4UWQA 4G9JA 1MF8A 2QJCA 4H2FA 2R17A 3HVQA 3CK2A 3IVDA 4LU9A 3QFMA 5B8IA 3E7BA 3H67A 4UT3B 2Z72A 1KBPA 3DW8C 4DHLA 4FBKA 3PSNA 1S70A 3IB7A 4TUIA 1USHA 3IVEA 3JYFA
chains in the Genus database with same CATH superfamily
1QHWA 2BDXA 4WWLA 4UT2A 3V4YA 1S3MA 3T1IA 4O43A 3P71C 1T70A 3D03A 2GJUA 3C5WC 2AHDA 2O8AA 2HYPA 4KBPA 3QFKA 2DXNA 4ORCA 4Q7FA 1AUIA 2O8GA 2NPPC 2ZBMA 3AUZA 4O4KA 2JOGA 5HPEA 1IT6A 2ZO9B 3PSOA 1FJMA 3H69A 1XZWA 4ZVZA 2KKNA 2HYOA 1JK7A 1OIDA 4FBWA 4ORBA 2CV9A 1S3NA 4F0ZA 2IE4C 3EGGA 5JJTA 2QFPA 4JA7A 3H62B 3ICFA 4H1YP 4ZX2A 5JPEA 1Z2XA 3RL3A 5INBA 2BQ8X 2YEQA 1SU1A 4MP0A 2WDDA 1M63A 4H1SA 5J28A 4H2IA 3RL4A 4V0XA 4HD0A 4V0WA 2NYLC 4NZVA 1V73A 1HPUA 2Q8UA 3H66A 1U32A 3DSCA 4FBQA 2P6BA 1II7A 1NNWA 3E7AA 3KBPA 3QFOA 4IYPC 2QFRA 1OI8A 1T71A 4YKEA 5GTUA 3IB8A 2NXFA 3ZU0A 1S95A 4B2OA 1HO5A 4TUGA 2WDFA 3LL8A 2XMOA 3AV0A 1G5BA 2HY1A 2Z1AA 4ORAA 3E0JA 4M0VA 3RQZA 4I5NC 5JPFA 2Z06A 4H2GA 4V0VA 3H61A 1UF3A 3TGHA 4H2BA 4FCXA 3H64A 2USHA 3QFNA 4KKZA 4O5GA 2YVTA 4I5LC 1OIEA 3C9FA 3H60A 5EQVA 4MOVA 5IOHA 3K7VC 3FGAC 3THOB 2WDCA 2IE3C 5DNYA 4O24A 1TCOA 3H68A 3EGHA 3QG5C 1UTEA 3RL5A 1W24A 4LTYA 1WARA 4MOYA 3THNA 3ZTVA 1S8EA 3N5UA 1Z2WA 4XPNA 4JA9A 4LACC 4J6OA 2BCDA 4OR9A 1WAO1 2IAEC 1S3LA 3DSDA 1XM7A 3FLOA 3H63A 2A22A 4DT2A 2DFJA 4IL1A 1QFCA 3K7WC 5C1VA 3GVEA 4UT3A 2WDEA 1HP1A 4DSYA 2NYMC 5F3WA 4UWQA 4G9JA 1MF8A 2QJCA 4H2FA 2R17A 3HVQA 3CK2A 3IVDA 4LU9A 3QFMA 5B8IA 3E7BA 3H67A 4UT3B 2Z72A 1KBPA 3DW8C 4DHLA 4FBKA 3PSNA 1S70A 3IB7A 4TUIA 2DXLA 2ZOAA 1USHA 3IVEA 3JYFA
chains in the Genus database with same CATH topology
1QHWA 2BDXA 4WWLA 4UT2A 3V4YA 1S3MA 3T1IA 4O43A 3P71C 1T70A 3D03A 2GJUA 3C5WC 2AHDA 2O8AA 2HYPA 4KBPA 3QFKA 2DXNA 4ORCA 4Q7FA 1AUIA 2O8GA 2NPPC 2ZBMA 3AUZA 4O4KA 2JOGA 5HPEA 1IT6A 2ZO9B 3PSOA 1FJMA 3H69A 1XZWA 4ZVZA 2KKNA 2HYOA 1JK7A 1OIDA 4FBWA 4ORBA 2CV9A 1S3NA 4F0ZA 2IE4C 3EGGA 5JJTA 2QFPA 4JA7A 3H62B 3ICFA 4H1YP 4ZX2A 5JPEA 1Z2XA 3RL3A 5INBA 2BQ8X 2YEQA 1SU1A 4MP0A 2WDDA 1M63A 4H1SA 5J28A 4H2IA 3RL4A 4V0XA 4HD0A 4V0WA 2NYLC 4NZVA 1V73A 1HPUA 2Q8UA 3H66A 1U32A 3DSCA 4FBQA 2P6BA 1II7A 1NNWA 3E7AA 3KBPA 3QFOA 4IYPC 2QFRA 1OI8A 1T71A 4YKEA 5GTUA 3IB8A 2NXFA 3ZU0A 1S95A 4B2OA 1HO5A 4TUGA 2WDFA 3LL8A 2XMOA 3AV0A 1G5BA 2HY1A 2Z1AA 4ORAA 3E0JA 4M0VA 3RQZA 4I5NC 5JPFA 2Z06A 4H2GA 4V0VA 3H61A 1UF3A 3TGHA 4H2BA 4FCXA 3H64A 2USHA 3QFNA 4KKZA 4O5GA 2YVTA 4I5LC 1OIEA 3C9FA 3H60A 5EQVA 4MOVA 5IOHA 3K7VC 3FGAC 3THOB 2WDCA 2IE3C 5DNYA 4O24A 1TCOA 3H68A 3EGHA 3QG5C 1UTEA 3RL5A 1W24A 4LTYA 1WARA 4MOYA 3THNA 3ZTVA 1S8EA 3N5UA 1Z2WA 4XPNA 4JA9A 4LACC 4J6OA 2BCDA 4OR9A 1WAO1 2IAEC 1S3LA 3DSDA 1XM7A 3FLOA 3H63A 2A22A 4DT2A 2DFJA 4IL1A 1QFCA 3K7WC 5C1VA 3GVEA 4UT3A 2WDEA 1HP1A 4DSYA 2NYMC 5F3WA 4UWQA 4G9JA 1MF8A 2QJCA 4H2FA 2R17A 3HVQA 3CK2A 3IVDA 4LU9A 3QFMA 5B8IA 3E7BA 3H67A 4UT3B 2Z72A 1KBPA 3DW8C 4DHLA 4FBKA 3PSNA 1S70A 3IB7A 4TUIA 2DXLA 2ZOAA 1USHA 3IVEA 3JYFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QHW A;  2BDX A;  4WWL A;  4UT2 A;  3V4Y A;  1S3M A;  3T1I A;  4O43 A;  3P71 C;  1T70 A;  2GJU A;  3C5W C;  2AHD A;  2O8A A;  2HYP A;  4KBP A;  3QFK A;  4ORC A;  4Q7F A;  1AUI A;  2O8G A;  2NPP C;  2ZBM A;  3AUZ A;  4O4K A;  2JOG A;  5HPE A;  1IT6 A;  3PSO A;  1FJM A;  3H69 A;  1XZW A;  4ZVZ A;  2KKN A;  2HYO A;  1JK7 A;  1OID A;  4FBW A;  4ORB A;  2CV9 A;  1S3N A;  4F0Z A;  2IE4 C;  3EGG A;  5JJT A;  2QFP A;  4JA7 A;  3H62 B;  3ICF A;  4H1Y P;  4ZX2 A;  5JPE A;  1Z2X A;  3RL3 A;  5INB A;  2BQ8 X;  1SU1 A;  4MP0 A;  2WDD A;  1M63 A;  4H1S A;  5J28 A;  4H2I A;  3RL4 A;  4V0X A;  4HD0 A;  4V0W A;  2NYL C;  4NZV A;  1V73 A;  1HPU A;  2Q8U A;  3H66 A;  1U32 A;  3DSC A;  4FBQ A;  2P6B A;  1II7 A;  1NNW A;  3E7A A;  3KBP A;  3QFO A;  4IYP C;  2QFR A;  1OI8 A;  1T71 A;  4YKE A;  5GTU A;  3IB8 A;  2NXF A;  3ZU0 A;  1S95 A;  4B2O A;  1HO5 A;  4TUG A;  2WDF A;  3LL8 A;  2XMO A;  3AV0 A;  1G5B A;  2HY1 A;  2Z1A A;  4ORA A;  4M0V A;  3RQZ A;  4I5N C;  5JPF A;  2Z06 A;  4H2G A;  4V0V A;  3H61 A;  1UF3 A;  3TGH A;  4H2B A;  4FCX A;  3H64 A;  2USH A;  3QFN A;  4KKZ A;  4O5G A;  2YVT A;  4I5L C;  1OIE A;  3C9F A;  3H60 A;  5EQV A;  4MOV A;  5IOH A;  3K7V C;  3FGA C;  3THO B;  2WDC A;  2IE3 C;  5DNY A;  4O24 A;  1TCO A;  3H68 A;  3EGH A;  3QG5 C;  1UTE A;  3RL5 A;  1W24 A;  4LTY A;  1WAR A;  4MOY A;  3THN A;  3ZTV A;  1S8E A;  3N5U A;  1Z2W A;  4XPN A;  4JA9 A;  4LAC C;  4J6O A;  2BCD A;  4OR9 A;  1WAO 1;  2IAE C;  1S3L A;  3DSD A;  1XM7 A;  3H63 A;  2A22 A;  4DT2 A;  2DFJ A;  4IL1 A;  1QFC A;  3K7W C;  5C1V A;  3GVE A;  4UT3 A;  2WDE A;  1HP1 A;  4DSY A;  2NYM C;  5F3W A;  4UWQ A;  4G9J A;  1MF8 A;  2QJC A;  4H2F A;  2R17 A;  3HVQ A;  3CK2 A;  3IVD A;  4LU9 A;  3QFM A;  5B8I A;  3E7B A;  3H67 A;  4UT3 B;  2Z72 A;  1KBP A;  3DW8 C;  4DHL A;  4FBK A;  3PSN A;  1S70 A;  3IB7 A;  4TUI A;  1USH A;  3IVE A;  3JYF A; 
#chains in the Genus database with same CATH topology
 1QHW A;  2BDX A;  4WWL A;  4UT2 A;  3V4Y A;  1S3M A;  3T1I A;  4O43 A;  3P71 C;  1T70 A;  3D03 A;  2GJU A;  3C5W C;  2AHD A;  2O8A A;  2HYP A;  4KBP A;  3QFK A;  2DXN A;  4ORC A;  4Q7F A;  1AUI A;  2O8G A;  2NPP C;  2ZBM A;  3AUZ A;  4O4K A;  2JOG A;  5HPE A;  1IT6 A;  2ZO9 B;  3PSO A;  1FJM A;  3H69 A;  1XZW A;  4ZVZ A;  2KKN A;  2HYO A;  1JK7 A;  1OID A;  4FBW A;  4ORB A;  2CV9 A;  1S3N A;  4F0Z A;  2IE4 C;  3EGG A;  5JJT A;  2QFP A;  4JA7 A;  3H62 B;  3ICF A;  4H1Y P;  4ZX2 A;  5JPE A;  1Z2X A;  3RL3 A;  5INB A;  2BQ8 X;  2YEQ A;  1SU1 A;  4MP0 A;  2WDD A;  1M63 A;  4H1S A;  5J28 A;  4H2I A;  3RL4 A;  4V0X A;  4HD0 A;  4V0W A;  2NYL C;  4NZV A;  1V73 A;  1HPU A;  2Q8U A;  3H66 A;  1U32 A;  3DSC A;  4FBQ A;  2P6B A;  1II7 A;  1NNW A;  3E7A A;  3KBP A;  3QFO A;  4IYP C;  2QFR A;  1OI8 A;  1T71 A;  4YKE A;  5GTU A;  3IB8 A;  2NXF A;  3ZU0 A;  1S95 A;  4B2O A;  1HO5 A;  4TUG A;  2WDF A;  3LL8 A;  2XMO A;  3AV0 A;  1G5B A;  2HY1 A;  2Z1A A;  4ORA A;  3E0J A;  4M0V A;  3RQZ A;  4I5N C;  5JPF A;  2Z06 A;  4H2G A;  4V0V A;  3H61 A;  1UF3 A;  3TGH A;  4H2B A;  4FCX A;  3H64 A;  2USH A;  3QFN A;  4KKZ A;  4O5G A;  2YVT A;  4I5L C;  1OIE A;  3C9F A;  3H60 A;  5EQV A;  4MOV A;  5IOH A;  3K7V C;  3FGA C;  3THO B;  2WDC A;  2IE3 C;  5DNY A;  4O24 A;  1TCO A;  3H68 A;  3EGH A;  3QG5 C;  1UTE A;  3RL5 A;  1W24 A;  4LTY A;  1WAR A;  4MOY A;  3THN A;  3ZTV A;  1S8E A;  3N5U A;  1Z2W A;  4XPN A;  4JA9 A;  4LAC C;  4J6O A;  2BCD A;  4OR9 A;  1WAO 1;  2IAE C;  1S3L A;  3DSD A;  1XM7 A;  3FLO A;  3H63 A;  2A22 A;  4DT2 A;  2DFJ A;  4IL1 A;  1QFC A;  3K7W C;  5C1V A;  3GVE A;  4UT3 A;  2WDE A;  1HP1 A;  4DSY A;  2NYM C;  5F3W A;  4UWQ A;  4G9J A;  1MF8 A;  2QJC A;  4H2F A;  2R17 A;  3HVQ A;  3CK2 A;  3IVD A;  4LU9 A;  3QFM A;  5B8I A;  3E7B A;  3H67 A;  4UT3 B;  2Z72 A;  1KBP A;  3DW8 C;  4DHL A;  4FBK A;  3PSN A;  1S70 A;  3IB7 A;  4TUI A;  2DXL A;  2ZOA A;  1USH A;  3IVE A;  3JYF A; 
#chains in the Genus database with same CATH homology
 1QHW A;  2BDX A;  4WWL A;  4UT2 A;  3V4Y A;  1S3M A;  3T1I A;  4O43 A;  3P71 C;  1T70 A;  3D03 A;  2GJU A;  3C5W C;  2AHD A;  2O8A A;  2HYP A;  4KBP A;  3QFK A;  2DXN A;  4ORC A;  4Q7F A;  1AUI A;  2O8G A;  2NPP C;  2ZBM A;  3AUZ A;  4O4K A;  2JOG A;  5HPE A;  1IT6 A;  2ZO9 B;  3PSO A;  1FJM A;  3H69 A;  1XZW A;  4ZVZ A;  2KKN A;  2HYO A;  1JK7 A;  1OID A;  4FBW A;  4ORB A;  2CV9 A;  1S3N A;  4F0Z A;  2IE4 C;  3EGG A;  5JJT A;  2QFP A;  4JA7 A;  3H62 B;  3ICF A;  4H1Y P;  4ZX2 A;  5JPE A;  1Z2X A;  3RL3 A;  5INB A;  2BQ8 X;  2YEQ A;  1SU1 A;  4MP0 A;  2WDD A;  1M63 A;  4H1S A;  5J28 A;  4H2I A;  3RL4 A;  4V0X A;  4HD0 A;  4V0W A;  2NYL C;  4NZV A;  1V73 A;  1HPU A;  2Q8U A;  3H66 A;  1U32 A;  3DSC A;  4FBQ A;  2P6B A;  1II7 A;  1NNW A;  3E7A A;  3KBP A;  3QFO A;  4IYP C;  2QFR A;  1OI8 A;  1T71 A;  4YKE A;  5GTU A;  3IB8 A;  2NXF A;  3ZU0 A;  1S95 A;  4B2O A;  1HO5 A;  4TUG A;  2WDF A;  3LL8 A;  2XMO A;  3AV0 A;  1G5B A;  2HY1 A;  2Z1A A;  4ORA A;  3E0J A;  4M0V A;  3RQZ A;  4I5N C;  5JPF A;  2Z06 A;  4H2G A;  4V0V A;  3H61 A;  1UF3 A;  3TGH A;  4H2B A;  4FCX A;  3H64 A;  2USH A;  3QFN A;  4KKZ A;  4O5G A;  2YVT A;  4I5L C;  1OIE A;  3C9F A;  3H60 A;  5EQV A;  4MOV A;  5IOH A;  3K7V C;  3FGA C;  3THO B;  2WDC A;  2IE3 C;  5DNY A;  4O24 A;  1TCO A;  3H68 A;  3EGH A;  3QG5 C;  1UTE A;  3RL5 A;  1W24 A;  4LTY A;  1WAR A;  4MOY A;  3THN A;  3ZTV A;  1S8E A;  3N5U A;  1Z2W A;  4XPN A;  4JA9 A;  4LAC C;  4J6O A;  2BCD A;  4OR9 A;  1WAO 1;  2IAE C;  1S3L A;  3DSD A;  1XM7 A;  3FLO A;  3H63 A;  2A22 A;  4DT2 A;  2DFJ A;  4IL1 A;  1QFC A;  3K7W C;  5C1V A;  3GVE A;  4UT3 A;  2WDE A;  1HP1 A;  4DSY A;  2NYM C;  5F3W A;  4UWQ A;  4G9J A;  1MF8 A;  2QJC A;  4H2F A;  2R17 A;  3HVQ A;  3CK2 A;  3IVD A;  4LU9 A;  3QFM A;  5B8I A;  3E7B A;  3H67 A;  4UT3 B;  2Z72 A;  1KBP A;  3DW8 C;  4DHL A;  4FBK A;  3PSN A;  1S70 A;  3IB7 A;  4TUI A;  2DXL A;  2ZOA A;  1USH A;  3IVE A;  3JYF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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