3KDEC

Crystal structure of the thap domain from d. melanogaster p-element transposase in complex with its natural dna binding site
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
76
structure length
74
Chain Sequence
MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAKGQTFKRRRLNADAVPSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.
pubmed doi rcsb
molecule keywords 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3'
molecule tags Dna binding protein/dna
source organism Drosophila melanogaster
total genus 13
structure length 74
sequence length 76
ec nomenclature
pdb deposition date 2009-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF05485 THAP THAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.40.180 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Herpes Virus-1 3kdeC01
2JM3A 3KDEC 2LAUA
chains in the Genus database with same CATH superfamily
2YHNA 3FAOA 2RI7A 1WIMA 2UZGA 3KNVA 4AUQB 2YURA 2QJ0A 4Z0RA 3N9LA 1WEOA 2IDAA 2JMIA 5KH9A 4IC3A 1X4JA 1T1HA 2BAYA 2L7PA 1CHCA 4ZUXU 2OWAA 3C6WA 2F42A 1WILA 4O62A 4GB0A 3SOXA 4OGCA 1MM3A 2MNZA 3SOWA 2LRIC 2KFTA 1VD4A 1X4IA 3LVQE 5TRBA 5H1UA 4TKPB 4WZ0A 2L5UA 1HYJA 1K2FA 5G0FA 1BORA 3EB6A 3FL2A 4YBTA 5FB0A 4FK5A 2VJFB 2L75A 5H9MA 4A0CD 5SVIB 4GNGA 4W4UA 4YATA 3ASLA 4IC2A 2LGLA 2ECWA 2LDRA 3ZPVE 2JMDA 4CA1A 1WEWA 2VPBA 3MHSA 3PUQA 3RPGB 2VP7A 2CSYA 2KGGA 2CKLB 1DCQA 2ECIA 1WFKA 4S3OB 5G05B 5D1MB 5FB1A 3L1ZB 1ZBDB 3O70A 4I7DA 2CSVA 3O34A 3SUBA 4R8PK 2MKEA 2P57A 2EODA 3SOUA 1JM7B 3ZNIA 4L7XA 2FFWA 5K3QA 2LXHC 3GL6A 5C13A 4B7YC 3M62A 4QF3A 5EYAF 3DDTA 4CCGX 2IQJA 3N9OA 2EA6A 2H0DA 2ECJA 4ZDTA 3MHHA 2QICA 4FIPA 5JG6A 5H1VA 5AIUA 4BHWA 2JMJA 2LAUA 4C9ZA 2DJAA 3SHBA 2KIZA 2F6NA 2FUIA 3ZTGA 3U5MA 3LVRE 3FJUB 3IHPA 4GNFA 4NN2A 1DVPA 2JRJA 4ZQLA 2C2LA 2B0OE 2CT2A 2K1JA 3T7LA 3M63A 3U5NA 4YADA 4H9DA 2YW8A 5J3XA 3FM8C 2LQ6A 3U5PA 3O36A 2YQMA 2D8SA 4WZ2A 4QF2A 2RSDA 4V3LC 3LQJA 2YREA 2CSZA 2NAAA 2VPEA 2L80A 4A4BA 1U6GB 1WEVA 2ECTA 5TABA 2LV9A 4L58A 2XOYA 2KWJA 3HCSA 2VJFA 4FJCA 1WGMA 5SVIA 4GNEA 4OGEA 4AYCB 2G43A 2RR4A 2KWNA 5TDRA 5H1TA 5KH7A 4BBQA 3M7KA 3KV5A 2CKLA 2K4DA 3FANA 5B78A 4YABA 2KWOA 3FEHA 1Z6UA 3GV4A 3N9QA 4LJNA 4YC9A 2K16A 3H7HA 2G45A 2XP0A 2OXQC 4F52B 1JOCA 3ZVYA 3NG2A 1MM2A 1JM7A 2VJEB 4LADB 2ZETC 3DWDA 5LKUA 1WEEA 3O7AA 3VK6A 4Z0OA 2AN6A 1WEQA 2FD4A 4WA6A 2YHOA 2CONA 3KQIA 3PHDA 3ZPV1 2Y43A 4UP0A 3KDEC 2M85A 1FP0A 4V3KC 2I50A 1G25A 4R2YA 2XEUA 2PUYA 4LK9A 2MA6A 3DPLR 5TBNA 2KYUA 4R7EA 4QQ4A 2MUMA 3V43A 3LJUX 2ECVA 5B75A 3DQVR 2M1RA 1WENA 2XOCA 2YVRA 3T6RA 1V87A 4B86C 5AITA 4O64A 4I7CA 2KE1A 2XB1A 2KR4A 2LXPC 3LRQA 3PLWA 2VPGA 2E61A 2CRWA 3PURA 5LKZA 3N9PA 2MD7B 2M6MA 5SVXA 1N87A 4UP5A 4MSXA 2MNYA 2ECNA 4A49A 1RMDA 2E6RA 2CRRA 1WE9A 2M3HA 3HTKC 1WEPA 4F1PA 2DSMA 5FEYA 3C5KA 4N4FA 5TDWA 3MDBC 2MIQA 4AYCA 3O35A 2YSJA 5B8DA 5I3LA 3LQHA 2D8UA 2LGVA 3HCUA 5D1KB 2YYRA 1VYXA 1IYMA 2EGPA 3HCTA 2DX8A 3L1XA 2KKYA 5DKAA 1Z60A 2KWKA 5B77A 4LKAA 2E6SA 3JUEA 3I2DA 5SVYA 4AP4A 4P5OB 4PPEA 4PTBA 2VJEA 2KREA 2K17A 3QZVA 3LQIA 3KV6A 5D1LB 1WEUA 2Y1NA 1F62A 4LLBA 2LGKA 4WZ3B 5B76A 2KKXA 3O47A 4YAXA 3N9NA 4X3GA 2FUUA 4N3WA 2C2VS 4YBSA 3O37A 1VFYA 1HYIA 3N9MA 5LCWB 5LKXA 5G04B 3T9KA 2FSAA 2LGGA 4GNDA 3U5OA 5B79A 2JM3A 4AVXA 1LDJB 2G6QA 5FERA 4I7BA 4YBMA 2MD8C 2JUNA 1Z2QA 2EGMA 4A4CA 4Q6FA 2KGIA 2MA5A 3RPGC 4MVTA 2YSMA 3ZVZB 4S3OC 4UI9B 1XWHA 1WESA 2LN0A 3Q1DA 2VPDA 2ECGA 3RTRB 2KU3A 2MT5A 4FO9A 2QIZA 2YT5A 3EB5A 2XOZA 2VNFA 1LDKC 5DINA 5LKTA 3E2DA 5C11A 3M99A 3ZYQA 4XI1A 2EXUA 2YUCA 2L43A 2HDPA 3O33A 1FBVA 5KH3A 3LDYA 2HYED 1E4UA 2YU4A 2M13A 1WEMA 2PNXA 2YQLA 2H0DB 3L11A 1MBMA 2F6JA 1X4UA 2Y1MA 2L0BA
chains in the Genus database with same CATH topology
2KKYA 3LVRE 3PLWA 1DCQA 2YREA 2JUNA 3FJUB 4OGCA 3MDBC 2EGMA 3DDTA 2IQJA 2XOZA 2E61A 2CRWA 3DWDA 3E2DA 4QQ4A 4Z0RA 5K3QA 5SVIB 3M7KA 3JUEA 3LJUX 5SVXA 2CSVA 2EXUA 2XOYA 3SUBA 2B0OE 2MKEA 3LVQE 5SVYA 2P57A 2D8UA 3T9KA 4H9DA 2L7PA 2XOCA 4Z0OA 2LAUA 2DJAA 3FEHA 2FD4A 2YVRA 3FM8C 3LDYA 2CRRA 3O47A 5SVIA 2OWAA 2M13A 3H7HA 2CONA 2XP0A 4OGEA 2FFWA 2JM3A 4O62A 4F1PA 3Q1DA 2KKXA 3KDEC 2RR4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JM3 A;  3KDE C;  2LAU A; 
#chains in the Genus database with same CATH topology
 2YHN A;  3FAO A;  2RI7 A;  1WIM A;  2UZG A;  3KNV A;  4AUQ B;  2YUR A;  2QJ0 A;  4Z0R A;  3N9L A;  1WEO A;  2IDA A;  2JMI A;  5KH9 A;  4IC3 A;  1X4J A;  1T1H A;  2BAY A;  2L7P A;  1CHC A;  4ZUX U;  2OWA A;  3C6W A;  2F42 A;  1WIL A;  4O62 A;  4GB0 A;  3SOX A;  4OGC A;  1MM3 A;  2MNZ A;  3SOW A;  2LRI C;  2KFT A;  1VD4 A;  1X4I A;  3LVQ E;  5TRB A;  5H1U A;  4TKP B;  4WZ0 A;  2L5U A;  1HYJ A;  1K2F A;  5G0F A;  1BOR A;  3EB6 A;  3FL2 A;  4YBT A;  5FB0 A;  4FK5 A;  2VJF B;  2L75 A;  5H9M A;  4A0C D;  5SVI B;  4GNG A;  4W4U A;  4YAT A;  3ASL A;  4IC2 A;  2LGL A;  2ECW A;  2LDR A;  3ZPV E;  2JMD A;  4CA1 A;  1WEW A;  2VPB A;  3MHS A;  3PUQ A;  3RPG B;  2VP7 A;  2CSY A;  2KGG A;  2CKL B;  1DCQ A;  2ECI A;  1WFK A;  4S3O B;  5G05 B;  5D1M B;  5FB1 A;  3L1Z B;  1ZBD B;  3O70 A;  4I7D A;  2CSV A;  3O34 A;  3SUB A;  4R8P K;  2MKE A;  2P57 A;  2EOD A;  3SOU A;  1JM7 B;  3ZNI A;  4L7X A;  2FFW A;  5K3Q A;  2LXH C;  3GL6 A;  5C13 A;  4B7Y C;  3M62 A;  4QF3 A;  5EYA F;  3DDT A;  4CCG X;  2IQJ A;  3N9O A;  2EA6 A;  2H0D A;  2ECJ A;  4ZDT A;  3MHH A;  2QIC A;  4FIP A;  5JG6 A;  5H1V A;  5AIU A;  4BHW A;  2JMJ A;  2LAU A;  4C9Z A;  2DJA A;  3SHB A;  2KIZ A;  2F6N A;  2FUI A;  3ZTG A;  3U5M A;  3LVR E;  3FJU B;  3IHP A;  4GNF A;  4NN2 A;  1DVP A;  2JRJ A;  4ZQL A;  2C2L A;  2B0O E;  2CT2 A;  2K1J A;  3T7L A;  3M63 A;  3U5N A;  4YAD A;  4H9D A;  2YW8 A;  5J3X A;  3FM8 C;  2LQ6 A;  3U5P A;  3O36 A;  2YQM A;  2D8S A;  4WZ2 A;  4QF2 A;  2RSD A;  4V3L C;  3LQJ A;  2YRE A;  2CSZ A;  2NAA A;  2VPE A;  2L80 A;  4A4B A;  1U6G B;  1WEV A;  2ECT A;  5TAB A;  2LV9 A;  4L58 A;  2XOY A;  2KWJ A;  3HCS A;  2VJF A;  4FJC A;  1WGM A;  5SVI A;  4GNE A;  4OGE A;  4AYC B;  2G43 A;  2RR4 A;  2KWN A;  5TDR A;  5H1T A;  5KH7 A;  4BBQ A;  3M7K A;  3KV5 A;  2CKL A;  2K4D A;  3FAN A;  5B78 A;  4YAB A;  2KWO A;  3FEH A;  1Z6U A;  3GV4 A;  3N9Q A;  4LJN A;  4YC9 A;  2K16 A;  3H7H A;  2G45 A;  2XP0 A;  2OXQ C;  4F52 B;  1JOC A;  3ZVY A;  3NG2 A;  1MM2 A;  1JM7 A;  2VJE B;  4LAD B;  2ZET C;  3DWD A;  5LKU A;  1WEE A;  3O7A A;  3VK6 A;  4Z0O A;  2AN6 A;  1WEQ A;  2FD4 A;  4WA6 A;  2YHO A;  2CON A;  3KQI A;  3PHD A;  3ZPV 1;  2Y43 A;  4UP0 A;  3KDE C;  2M85 A;  1FP0 A;  4V3K C;  2I50 A;  1G25 A;  4R2Y A;  2XEU A;  2PUY A;  4LK9 A;  2MA6 A;  3DPL R;  5TBN A;  2KYU A;  4R7E A;  4QQ4 A;  2MUM A;  3V43 A;  3LJU X;  2ECV A;  5B75 A;  3DQV R;  2M1R A;  1WEN A;  2XOC A;  2YVR A;  3T6R A;  1V87 A;  4B86 C;  5AIT A;  4O64 A;  4I7C A;  2KE1 A;  2XB1 A;  2KR4 A;  2LXP C;  3LRQ A;  3PLW A;  2VPG A;  2E61 A;  2CRW A;  3PUR A;  5LKZ A;  3N9P A;  2MD7 B;  2M6M A;  5SVX A;  1N87 A;  4UP5 A;  4MSX A;  2MNY A;  2ECN A;  4A49 A;  1RMD A;  2E6R A;  2CRR A;  1WE9 A;  2M3H A;  3HTK C;  1WEP A;  4F1P A;  2DSM A;  5FEY A;  3C5K A;  4N4F A;  5TDW A;  3MDB C;  2MIQ A;  4AYC A;  3O35 A;  2YSJ A;  5B8D A;  5I3L A;  3LQH A;  2D8U A;  2LGV A;  3HCU A;  5D1K B;  2YYR A;  1VYX A;  1IYM A;  2EGP A;  3HCT A;  2DX8 A;  3L1X A;  2KKY A;  5DKA A;  1Z60 A;  2KWK A;  5B77 A;  4LKA A;  2E6S A;  3JUE A;  3I2D A;  5SVY A;  4AP4 A;  4P5O B;  4PPE A;  4PTB A;  2VJE A;  2KRE A;  2K17 A;  3QZV A;  3LQI A;  3KV6 A;  5D1L B;  1WEU A;  2Y1N A;  1F62 A;  4LLB A;  2LGK A;  4WZ3 B;  5B76 A;  2KKX A;  3O47 A;  4YAX A;  3N9N A;  4X3G A;  2FUU A;  4N3W A;  2C2V S;  4YBS A;  3O37 A;  1VFY A;  1HYI A;  3N9M A;  5LCW B;  5LKX A;  5G04 B;  3T9K A;  2FSA A;  2LGG A;  4GND A;  3U5O A;  5B79 A;  2JM3 A;  4AVX A;  1LDJ B;  2G6Q A;  5FER A;  4I7B A;  4YBM A;  2MD8 C;  2JUN A;  1Z2Q A;  2EGM A;  4A4C A;  4Q6F A;  2KGI A;  2MA5 A;  3RPG C;  4MVT A;  2YSM A;  3ZVZ B;  4S3O C;  4UI9 B;  1XWH A;  1WES A;  2LN0 A;  3Q1D A;  2VPD A;  2ECG A;  3RTR B;  2KU3 A;  2MT5 A;  4FO9 A;  2QIZ A;  2YT5 A;  3EB5 A;  2XOZ A;  2VNF A;  1LDK C;  5DIN A;  5LKT A;  3E2D A;  5C11 A;  3M99 A;  3ZYQ A;  4XI1 A;  2EXU A;  2YUC A;  2L43 A;  2HDP A;  3O33 A;  1FBV A;  5KH3 A;  3LDY A;  2HYE D;  1E4U A;  2YU4 A;  2M13 A;  1WEM A;  2PNX A;  2YQL A;  2H0D B;  3L11 A;  1MBM A;  2F6J A;  1X4U A;  2Y1M A;  2L0B A; 
#chains in the Genus database with same CATH homology
 2KKY A;  3LVR E;  3PLW A;  1DCQ A;  2YRE A;  2JUN A;  3FJU B;  4OGC A;  3MDB C;  2EGM A;  3DDT A;  2IQJ A;  2XOZ A;  2E61 A;  2CRW A;  3DWD A;  3E2D A;  4QQ4 A;  4Z0R A;  5K3Q A;  5SVI B;  3M7K A;  3JUE A;  3LJU X;  5SVX A;  2CSV A;  2EXU A;  2XOY A;  3SUB A;  2B0O E;  2MKE A;  3LVQ E;  5SVY A;  2P57 A;  2D8U A;  3T9K A;  4H9D A;  2L7P A;  2XOC A;  4Z0O A;  2LAU A;  2DJA A;  3FEH A;  2FD4 A;  2YVR A;  3FM8 C;  3LDY A;  2CRR A;  3O47 A;  5SVI A;  2OWA A;  2M13 A;  3H7H A;  2CON A;  2XP0 A;  4OGE A;  2FFW A;  2JM3 A;  4O62 A;  4F1P A;  3Q1D A;  2KKX A;  3KDE C;  2RR4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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