3KHWA

Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/mexico/indre4487/2009(h1n1)
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
201
structure length
201
Chain Sequence
GPESVLVNTYQWIIRNWEIVKIQWSQDPTMLYNKMEFEPFQSLVPKATRSRYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGLRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTSGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Biological and structural characterization of a host-adapting amino acid in influenza virus.
pubmed doi rcsb
molecule tags Viral protein
source organism Influenza a virus (a/mexico/indre4487/2009(h1n1))
molecule keywords Polymerase PB2
total genus 54
structure length 201
sequence length 201
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-10-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.90 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3khwA02
3CW4A 2JDQD 3KHWA 3KC6A 4UADE 3L56A 3R2VA 2VY6A 4UAEF 2GMOA 4UAFE
chains in the Genus database with same CATH superfamily
3D2EB 1TI5A 1ZYWA 2LT8A 2LY5A 2MBKA 3M3ZA 2QWNA 2LR3A 3FZFA 1P0AA 3QI7A 5BPLA 5F0XA 1B3CA 1YUWA 3KOWA 1JKZA 5KK4A 1WWNA 1SEGA 5AQJA 1ICAA 2KHOA 1XRSB 2E3FA 1DKGD 1BA0A 2YIPA 1C55A 5F1XA 3I33A 5AQSA 3QMLA 1AHOA 5AQIA 4AAZA 4IO8A 5CY0A 3KC6A 1T1TA 1ZVGA 2QWLA 3KVGA 1NGDA 4KBOA 2I61A 2VY6A 5F2RA 3E7UX 2QWQA 1LQHA 1GPTA 5EX5A 1SNBA 2LKBA 5AQGA 2E3GA 5AQPA 2LJ7A 1T0ZA 5AQMA 1WT7A 5FPNA 3ATVA 1GPSA 3L6QA 2B68A 5AQRA 1BRZA 1KAYA 5EXWA 2D56A 1NGEA 1NH5A 1I2UA 5EVZA 2QWRA 2N66A 5BN9A 3KOZA 3D2FA 5BPNA 2KPYA 1LQIA 2ASCA 1NRAA 2LY6A 3LDPA 5AQFA 3C7NA 3BK3C 3ATUA 2YBRC 2LI7A 5AQLA 3PSMA 5FPMA 3AY9A 2LJMA 5AQNA 1BK8A 5AQKA 2V7ZA 2YC1C 3IUCA 4H5NA 1JXCA 2KBJA 3FZHA 4H5RA 1ATSA 1BA1A 2NY9X 1L4VA 2N2QA 1POIA 1B7DA 1MR4A 1CHZA 4H5VA 3GDQA 1DJTA 1NGIA 1SN1A 1ZYVA 3KP0A 5AQVA 1FH3A 3D2EA 2KBHA 5AQXA 1I6FA 1QQNA 2N2RA 3CQXA 1ZVEA 2QWMA 3HSCA 1JZAA 1C56A 1LQQA 1K8BA 4UJ0A 2E8AA 3KP1A 1NE5A 1I6GA 1T7BA 1NGHA 1HJOA 3KOYA 1AYJA 1PTXA 2ATBA 2KYQA 4HWIA 3A8YA 3D2FB 5BN8A 2SN3A 5AQZA 2K35A 2E88A 3GKUA 5FPDA 1P00A 4UAEF 1NGCA 4H5WA 2QW9A 3E7RL 4UAFE 5BPMA 3LDOA 1PE4A 3KHWA 1QQMA 1VNAA 2YEOA 4UADE 5AQOA 5FPEA 1BMRA 1BCGA 4FSVA 1T7AA 2KBKA 1DQ7A 1NGFA 1OZZA 2QXLA 1NGBA 3LDLA 2BUPA 1HX1A 2B3CA 2M8BB 3L4IA 2KJAA 1NPIA 2LN8A 3LDNA 4AEIA 1BUPA 1T7EA 1VNBA 1ZUTA 3GL1A 3R2VA 2GMOA 2YIOA 1SN4A 5AR0A 3CW4A 5AQYA 1KV0A 2BRZA 3SF4D 5AQQA 4FL9A 2YILA 5AQWA 4AB0A 4CQKA 1ZFUA 2A7TA 3KOXA 1UGLA 4HHFA 2N69A 3LDQA 2GL1A 3FE1A 2JDQD 2MN5A 3FZLA 3QFUA 2NY8X 1I2VA 1NRBA 2QWOA 3C7NB 5AQTA 2G2KA 1WMTA 4V1DC 5AQHA 1MYNA 1NGGA 4KYPA 1KAZA 2E0HA 2KSKA 3FZMA 3FZKA 4GNIA 1ATRA 1HPMA 1JZBA 1NGAA 1KAXA 1PX9A 1QQOA 2MZ0A 4HE7A 5EY4A 3JXUA 1OMYA 2E2FA 2QWPA 1ZU3A 4H5TA 1S3XA 3L56A 1CN2A 1N4NA 3QFPA 2KGQA 1NGJA 5AQUA
chains in the Genus database with same CATH topology
3D2EB 3QI7A 3M3ZA 2MBKA 2QWNA 3FZFA 5BPLA 5F0XA 1YUWA 5AQJA 2KHOA 1DKGD 1BA0A 2YIPA 5F1XA 3I33A 5AQSA 3QMLA 5AQIA 4IO8A 3KC6A 2QWLA 3KVGA 1NGDA 4KBOA 2VY6A 5F2RA 2QWQA 5EX5A 5AQGA 5AQPA 5AQMA 5FPNA 3ATVA 3L6QA 5AQRA 1KAYA 5EXWA 2D56A 1NGEA 5EVZA 2QWRA 5BN9A 3D2FA 5BPNA 3LDPA 5AQFA 3C7NA 3BK3C 3ATUA 5AQLA 5FPMA 3AY9A 5AQNA 5AQKA 2V7ZA 3IUCA 4H5NA 3FZHA 4H5RA 1ATSA 1BA1A 1POIA 4H5VA 3GDQA 1NGIA 5AQVA 3D2EA 5AQXA 3CQXA 1QQNA 2QWMA 3HSCA 2E8AA 1NGHA 1HJOA 4HWIA 3A8YA 3D2FB 5BN8A 5AQZA 2K35A 2E88A 5FPDA 4UAEF 1NGCA 4H5WA 2QW9A 4UAFE 5BPMA 3LDOA 3KHWA 1QQMA 5FPEA 4UADE 5AQOA 4FSVA 1NGFA 2QXLA 1NGBA 3LDLA 2BUPA 1HX1A 3L4IA 3LDNA 2LN8A 1BUPA 5AR0A 3GL1A 3R2VA 2GMOA 2YIOA 3CW4A 5AQYA 3SF4D 5AQQA 4FL9A 2YILA 5AQWA 3LDQA 3FZLA 3FE1A 2JDQD 2MN5A 3QFUA 2QWOA 3C7NB 5AQTA 5AQHA 1NGGA 1KAZA 3FZMA 3FZKA 4GNIA 1ATRA 1HPMA 1NGAA 1QQOA 1KAXA 5EY4A 3JXUA 2E2FA 2QWPA 4H5TA 1S3XA 3L56A 3QFPA 1NGJA 5AQUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CW4 A;  2JDQ D;  3KHW A;  3KC6 A;  4UAD E;  3L56 A;  3R2V A;  2VY6 A;  4UAE F;  2GMO A;  4UAF E; 
#chains in the Genus database with same CATH topology
 3D2E B;  1TI5 A;  1ZYW A;  2LT8 A;  2LY5 A;  2MBK A;  3M3Z A;  2QWN A;  2LR3 A;  3FZF A;  1P0A A;  3QI7 A;  5BPL A;  5F0X A;  1B3C A;  1YUW A;  3KOW A;  1JKZ A;  5KK4 A;  1WWN A;  1SEG A;  5AQJ A;  1ICA A;  2KHO A;  1XRS B;  2E3F A;  1DKG D;  1BA0 A;  2YIP A;  1C55 A;  5F1X A;  3I33 A;  5AQS A;  3QML A;  1AHO A;  5AQI A;  4AAZ A;  4IO8 A;  5CY0 A;  3KC6 A;  1T1T A;  1ZVG A;  2QWL A;  3KVG A;  1NGD A;  4KBO A;  2I61 A;  2VY6 A;  5F2R A;  3E7U X;  2QWQ A;  1LQH A;  1GPT A;  5EX5 A;  1SNB A;  2LKB A;  5AQG A;  2E3G A;  5AQP A;  2LJ7 A;  1T0Z A;  5AQM A;  1WT7 A;  5FPN A;  3ATV A;  1GPS A;  3L6Q A;  2B68 A;  5AQR A;  1BRZ A;  1KAY A;  5EXW A;  2D56 A;  1NGE A;  1NH5 A;  1I2U A;  5EVZ A;  2QWR A;  2N66 A;  5BN9 A;  3KOZ A;  3D2F A;  5BPN A;  2KPY A;  1LQI A;  2ASC A;  1NRA A;  2LY6 A;  3LDP A;  5AQF A;  3C7N A;  3BK3 C;  3ATU A;  2YBR C;  2LI7 A;  5AQL A;  3PSM A;  5FPM A;  3AY9 A;  2LJM A;  5AQN A;  1BK8 A;  5AQK A;  2V7Z A;  2YC1 C;  3IUC A;  4H5N A;  1JXC A;  2KBJ A;  3FZH A;  4H5R A;  1ATS A;  1BA1 A;  2NY9 X;  1L4V A;  2N2Q A;  1POI A;  1B7D A;  1MR4 A;  1CHZ A;  4H5V A;  3GDQ A;  1DJT A;  1NGI A;  1SN1 A;  1ZYV A;  3KP0 A;  5AQV A;  1FH3 A;  3D2E A;  2KBH A;  5AQX A;  1I6F A;  1QQN A;  2N2R A;  3CQX A;  1ZVE A;  2QWM A;  3HSC A;  1JZA A;  1C56 A;  1LQQ A;  1K8B A;  4UJ0 A;  2E8A A;  3KP1 A;  1NE5 A;  1I6G A;  1T7B A;  1NGH A;  1HJO A;  3KOY A;  1AYJ A;  1PTX A;  2ATB A;  2KYQ A;  4HWI A;  3A8Y A;  3D2F B;  5BN8 A;  2SN3 A;  5AQZ A;  2K35 A;  2E88 A;  3GKU A;  5FPD A;  1P00 A;  4UAE F;  1NGC A;  4H5W A;  2QW9 A;  3E7R L;  4UAF E;  5BPM A;  3LDO A;  1PE4 A;  3KHW A;  1QQM A;  1VNA A;  2YEO A;  4UAD E;  5AQO A;  5FPE A;  1BMR A;  1BCG A;  4FSV A;  1T7A A;  2KBK A;  1DQ7 A;  1NGF A;  1OZZ A;  2QXL A;  1NGB A;  3LDL A;  2BUP A;  1HX1 A;  2B3C A;  2M8B B;  3L4I A;  2KJA A;  1NPI A;  2LN8 A;  3LDN A;  4AEI A;  1BUP A;  1T7E A;  1VNB A;  1ZUT A;  3GL1 A;  3R2V A;  2GMO A;  2YIO A;  1SN4 A;  5AR0 A;  3CW4 A;  5AQY A;  1KV0 A;  2BRZ A;  3SF4 D;  5AQQ A;  4FL9 A;  2YIL A;  5AQW A;  4AB0 A;  4CQK A;  1ZFU A;  2A7T A;  3KOX A;  1UGL A;  4HHF A;  2N69 A;  3LDQ A;  2GL1 A;  3FE1 A;  2JDQ D;  2MN5 A;  3FZL A;  3QFU A;  2NY8 X;  1I2V A;  1NRB A;  2QWO A;  3C7N B;  5AQT A;  2G2K A;  1WMT A;  4V1D C;  5AQH A;  1MYN A;  1NGG A;  4KYP A;  1KAZ A;  2E0H A;  2KSK A;  3FZM A;  3FZK A;  4GNI A;  1ATR A;  1HPM A;  1JZB A;  1NGA A;  1KAX A;  1PX9 A;  1QQO A;  2MZ0 A;  4HE7 A;  5EY4 A;  3JXU A;  1OMY A;  2E2F A;  2QWP A;  1ZU3 A;  4H5T A;  1S3X A;  3L56 A;  1CN2 A;  1N4N A;  3QFP A;  2KGQ A;  1NGJ A;  5AQU A; 
#chains in the Genus database with same CATH homology
 3D2E B;  3QI7 A;  3M3Z A;  2MBK A;  2QWN A;  3FZF A;  5BPL A;  5F0X A;  1YUW A;  5AQJ A;  2KHO A;  1DKG D;  1BA0 A;  2YIP A;  5F1X A;  3I33 A;  5AQS A;  3QML A;  5AQI A;  4IO8 A;  3KC6 A;  2QWL A;  3KVG A;  1NGD A;  4KBO A;  2VY6 A;  5F2R A;  2QWQ A;  5EX5 A;  5AQG A;  5AQP A;  5AQM A;  5FPN A;  3ATV A;  3L6Q A;  5AQR A;  1KAY A;  5EXW A;  2D56 A;  1NGE A;  5EVZ A;  2QWR A;  5BN9 A;  3D2F A;  5BPN A;  3LDP A;  5AQF A;  3C7N A;  3BK3 C;  3ATU A;  5AQL A;  5FPM A;  3AY9 A;  5AQN A;  5AQK A;  2V7Z A;  3IUC A;  4H5N A;  3FZH A;  4H5R A;  1ATS A;  1BA1 A;  1POI A;  4H5V A;  3GDQ A;  1NGI A;  5AQV A;  3D2E A;  5AQX A;  3CQX A;  1QQN A;  2QWM A;  3HSC A;  2E8A A;  1NGH A;  1HJO A;  4HWI A;  3A8Y A;  3D2F B;  5BN8 A;  5AQZ A;  2K35 A;  2E88 A;  5FPD A;  4UAE F;  1NGC A;  4H5W A;  2QW9 A;  4UAF E;  5BPM A;  3LDO A;  3KHW A;  1QQM A;  5FPE A;  4UAD E;  5AQO A;  4FSV A;  1NGF A;  2QXL A;  1NGB A;  3LDL A;  2BUP A;  1HX1 A;  3L4I A;  3LDN A;  2LN8 A;  1BUP A;  5AR0 A;  3GL1 A;  3R2V A;  2GMO A;  2YIO A;  3CW4 A;  5AQY A;  3SF4 D;  5AQQ A;  4FL9 A;  2YIL A;  5AQW A;  3LDQ A;  3FZL A;  3FE1 A;  2JDQ D;  2MN5 A;  3QFU A;  2QWO A;  3C7N B;  5AQT A;  5AQH A;  1NGG A;  1KAZ A;  3FZM A;  3FZK A;  4GNI A;  1ATR A;  1HPM A;  1NGA A;  1QQO A;  1KAX A;  5EY4 A;  3JXU A;  2E2F A;  2QWP A;  4H5T A;  1S3X A;  3L56 A;  3QFP A;  1NGJ A;  5AQU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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