3LE4A

Crystal structure of the dgcr8 dimerization domain
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
55
structure length
55
Chain Sequence
PPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the dimerization domain of DiGeorge Critical Region 8
pubmed doi rcsb
molecule tags Nuclear protein
source organism Homo sapiens
molecule keywords Microprocessor complex subunit DGCR8
total genus 3
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2010-01-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 3le4A00
3KADA 1I5HW 2JMFA 3TC5A 1EG4A 3KAGA 1O6WA 2M3OW 2XP5A 1ZCNA 2M8JA 3KAHA 3L4HA 2DMVA 2XP9A 1NMVA 1TK7A 2ZR6A 1K9RA 2DJYA 2XP3A 1YW5A 1K9QA 2YSIA 2F21A 2ZR4A 4E5RA 4U86A 1F8AB 2M8IA 4QIBA 1WMVA 2XP8A 2YSHA 3OOBA 5CQ2A 2Q5AA 2DK1A 3KABA 2XPAA 3KAIA 2ZAJA 2ITKA 2YSFA 4U85A 2JV4A 3LE4A 4REXA 2ZQTA 3TDBA 3TCZA 4U84A 2E45A 2EZ5W 3WH0A 2YSGA 3KCEA 1WR7A 3KAFA 1EG3A 2DWVA 2XP4A 2ZQUA 2ZQVA 2L4JA 2DK7A 5AHTA 2JX8A 2XP6A 2RE3A 3ODKA 3NTPA 3CNGA 2ZR5A 2ZQSA 2XPBA 3M7NA 1PINA 2JXWA 2KXQA 2YSBA 2LAJA 1JMQA 3M85A 2BA1A 2XP7A 2MDIA
chains in the Genus database with same CATH superfamily
3KADA 1I5HW 2JMFA 3TC5A 4GLXA 1EG4A 3KAGA 1O6WA 2M3OW 5E62A 2XP5A 1ZCNA 5U47A 3FSBA 3LKXA 5E64A 2M8JA 3KAHA 3L4HA 3PQHA 2DMVA 2XP9A 3MQGA 1NMVA 1TK7A 2ZR6A 1K9RA 2DJYA 2Y8NB 2XP3A 3LKXB 1YW5A 1RP5A 1K9QA 2YSIA 2OWOA 2F21A 2ZR4A 4E5RA 4U86A 1F8AB 3FSCA 2M8IA 1FLCA 4QIBA 1WMVA 2XP8A 2YSHA 3OOBA 5CQ2A 2Q5AA 2DK1A 3KABA 2XPAA 2WADA 3KAIA 2ZAJA 2ITKA 2YSFA 4U85A 2JV4A 3LE4A 4REXA 2ZQTA 3TDBA 4U84A 3TCZA 2E45A 2EZ5W 5E5WA 5E66A 3FS8A 5E65A 3WH0A 2YSGA 2WAEA 1WR7A 3KCEA 3KAFA 3MCBA 1EG3A 2DWVA 1TR8A 2XP4A 2ZQUA 2YAJB 2ZQVA 2L4JA 2DK7A 3MCBB 5AHTA 2JX8A 2XP6A 2RE3A 3ODKA 3NTPA 3CNGA 4A0TA 2ZR5A 2ZQSA 2XPBA 3M7NA 3MQHA 1PINA 2JXWA 2KXQA 2YSBA 2QRVA 2LAJA 4A0UA 1JMQA 3M85A 2BA1A 2XP7A 2MDIA
chains in the Genus database with same CATH topology
3KADA 1I5HW 2JMFA 3TC5A 4GLXA 1EG4A 3KAGA 1O6WA 2M3OW 5E62A 2XP5A 1ZCNA 5U47A 3FSBA 3LKXA 5E64A 2M8JA 3KAHA 3L4HA 3PQHA 2DMVA 2XP9A 3MQGA 1NMVA 1TK7A 2ZR6A 1K9RA 2DJYA 2Y8NB 2XP3A 3LKXB 1YW5A 1RP5A 1K9QA 2YSIA 2OWOA 2F21A 2ZR4A 4E5RA 4U86A 1F8AB 3FSCA 2M8IA 1FLCA 4QIBA 1WMVA 2XP8A 2YSHA 3OOBA 5CQ2A 2Q5AA 2DK1A 3KABA 2XPAA 2WADA 3KAIA 2ZAJA 2ITKA 2YSFA 4U85A 2JV4A 3LE4A 4REXA 2ZQTA 3TDBA 4U84A 3TCZA 2E45A 2EZ5W 5E5WA 5E66A 3FS8A 5E65A 3WH0A 2YSGA 2WAEA 1WR7A 3KCEA 3KAFA 3MCBA 1EG3A 2DWVA 1TR8A 2XP4A 2ZQUA 2YAJB 2ZQVA 2L4JA 2DK7A 3MCBB 5AHTA 2JX8A 2XP6A 2RE3A 3ODKA 3NTPA 3CNGA 4A0TA 2ZR5A 2ZQSA 2XPBA 3M7NA 3MQHA 1PINA 2JXWA 2KXQA 2YSBA 2QRVA 2LAJA 4A0UA 1JMQA 3M85A 2BA1A 2XP7A 2MDIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KAD A;  1I5H W;  2JMF A;  3TC5 A;  1EG4 A;  3KAG A;  1O6W A;  2M3O W;  2XP5 A;  1ZCN A;  2M8J A;  3KAH A;  3L4H A;  2DMV A;  2XP9 A;  1NMV A;  1TK7 A;  2ZR6 A;  1K9R A;  2DJY A;  2XP3 A;  1YW5 A;  1K9Q A;  2YSI A;  2F21 A;  2ZR4 A;  4E5R A;  4U86 A;  1F8A B;  2M8I A;  4QIB A;  1WMV A;  2XP8 A;  2YSH A;  3OOB A;  5CQ2 A;  2Q5A A;  2DK1 A;  3KAB A;  2XPA A;  3KAI A;  2ZAJ A;  2ITK A;  2YSF A;  4U85 A;  2JV4 A;  3LE4 A;  4REX A;  2ZQT A;  3TDB A;  3TCZ A;  4U84 A;  2E45 A;  2EZ5 W;  3WH0 A;  2YSG A;  3KCE A;  1WR7 A;  3KAF A;  1EG3 A;  2DWV A;  2XP4 A;  2ZQU A;  2ZQV A;  2L4J A;  2DK7 A;  5AHT A;  2JX8 A;  2XP6 A;  2RE3 A;  3ODK A;  3NTP A;  3CNG A;  2ZR5 A;  2ZQS A;  2XPB A;  3M7N A;  1PIN A;  2JXW A;  2KXQ A;  2YSB A;  2LAJ A;  1JMQ A;  3M85 A;  2BA1 A;  2XP7 A;  2MDI A; 
#chains in the Genus database with same CATH topology
 3KAD A;  1I5H W;  2JMF A;  3TC5 A;  4GLX A;  1EG4 A;  3KAG A;  1O6W A;  2M3O W;  5E62 A;  2XP5 A;  1ZCN A;  5U47 A;  3FSB A;  3LKX A;  5E64 A;  2M8J A;  3KAH A;  3L4H A;  3PQH A;  2DMV A;  2XP9 A;  3MQG A;  1NMV A;  1TK7 A;  2ZR6 A;  1K9R A;  2DJY A;  2Y8N B;  2XP3 A;  3LKX B;  1YW5 A;  1RP5 A;  1K9Q A;  2YSI A;  2OWO A;  2F21 A;  2ZR4 A;  4E5R A;  4U86 A;  1F8A B;  3FSC A;  2M8I A;  1FLC A;  4QIB A;  1WMV A;  2XP8 A;  2YSH A;  3OOB A;  5CQ2 A;  2Q5A A;  2DK1 A;  3KAB A;  2XPA A;  2WAD A;  3KAI A;  2ZAJ A;  2ITK A;  2YSF A;  4U85 A;  2JV4 A;  3LE4 A;  4REX A;  2ZQT A;  3TDB A;  4U84 A;  3TCZ A;  2E45 A;  2EZ5 W;  5E5W A;  5E66 A;  3FS8 A;  5E65 A;  3WH0 A;  2YSG A;  2WAE A;  1WR7 A;  3KCE A;  3KAF A;  3MCB A;  1EG3 A;  2DWV A;  1TR8 A;  2XP4 A;  2ZQU A;  2YAJ B;  2ZQV A;  2L4J A;  2DK7 A;  3MCB B;  5AHT A;  2JX8 A;  2XP6 A;  2RE3 A;  3ODK A;  3NTP A;  3CNG A;  4A0T A;  2ZR5 A;  2ZQS A;  2XPB A;  3M7N A;  3MQH A;  1PIN A;  2JXW A;  2KXQ A;  2YSB A;  2QRV A;  2LAJ A;  4A0U A;  1JMQ A;  3M85 A;  2BA1 A;  2XP7 A;  2MDI A; 
#chains in the Genus database with same CATH homology
 3KAD A;  1I5H W;  2JMF A;  3TC5 A;  4GLX A;  1EG4 A;  3KAG A;  1O6W A;  2M3O W;  5E62 A;  2XP5 A;  1ZCN A;  5U47 A;  3FSB A;  3LKX A;  5E64 A;  2M8J A;  3KAH A;  3L4H A;  3PQH A;  2DMV A;  2XP9 A;  3MQG A;  1NMV A;  1TK7 A;  2ZR6 A;  1K9R A;  2DJY A;  2Y8N B;  2XP3 A;  3LKX B;  1YW5 A;  1RP5 A;  1K9Q A;  2YSI A;  2OWO A;  2F21 A;  2ZR4 A;  4E5R A;  4U86 A;  1F8A B;  3FSC A;  2M8I A;  1FLC A;  4QIB A;  1WMV A;  2XP8 A;  2YSH A;  3OOB A;  5CQ2 A;  2Q5A A;  2DK1 A;  3KAB A;  2XPA A;  2WAD A;  3KAI A;  2ZAJ A;  2ITK A;  2YSF A;  4U85 A;  2JV4 A;  3LE4 A;  4REX A;  2ZQT A;  3TDB A;  4U84 A;  3TCZ A;  2E45 A;  2EZ5 W;  5E5W A;  5E66 A;  3FS8 A;  5E65 A;  3WH0 A;  2YSG A;  2WAE A;  1WR7 A;  3KCE A;  3KAF A;  3MCB A;  1EG3 A;  2DWV A;  1TR8 A;  2XP4 A;  2ZQU A;  2YAJ B;  2ZQV A;  2L4J A;  2DK7 A;  3MCB B;  5AHT A;  2JX8 A;  2XP6 A;  2RE3 A;  3ODK A;  3NTP A;  3CNG A;  4A0T A;  2ZR5 A;  2ZQS A;  2XPB A;  3M7N A;  3MQH A;  1PIN A;  2JXW A;  2KXQ A;  2YSB A;  2QRV A;  2LAJ A;  4A0U A;  1JMQ A;  3M85 A;  2BA1 A;  2XP7 A;  2MDI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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