3NVLA

Crystal structure of phosphoglycerate mutase from trypanosoma brucei
Total Genus 199
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
199
Knots found
sequence length
549
structure length
549
Chain Sequence
LTLAAHKTLPRRKLVLVVLDGVGIGPRDEYDAVHVAKTPLMDALFNDPKHFRSICAHGTAVGLPTDADMGNSEVGHNALGAGRVVLQGASLVDDALESGEIFTSEGYRYLHGAFSQPGRTLHLIGLLSDGGVHSRDNQVYQILKHAGANGAKRIRVHALYDGRDVPDKTSFKFTDELEEVLAKLREGGCDARIASGGGRMFVTMDRYEADWSIVERGWRAQVLGEGRAFKSAREALTKFREEDANISDQYYPPFVIAGDDGRPIGTIEDGDAVLCFNFRGDRVIEMSRAFEEEEFDKFNRVRLPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRTSEEYLIGSGCNIFALSETQKFGHVTYFWNGNRSGKLSEERETFCEIPSDRVQFNQKPLMKSKEITDAAVDAIKSGKYDMIRINYPNGDMVGHTGDLKATITSLEAVDQSLQRLKEAVDSVNGVFLITADHGNSDDMVQRDKKGKPVRDAEGNLMPLTSHTLAPVPVFIGGAGLDPRVQMRTDLPRAGLANVTATFINLMGFEAPSDYEPSLIEVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of phosphoglycerate mutase from Trypanosoma brucei.
pubmed doi rcsb
source organism Trypanosoma brucei
molecule tags Isomerase
molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
total genus 199
structure length 549
sequence length 549
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date 2010-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3nvlA01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 3nvlA02
3NKNA 5L0BA 4CXUA 3DYCA 4CYSA 4TN0A 1N2KA 1ELZA 5IJSA 4YR1A 1ELYA 1SHNA 2W8SA 4LRDA 1B8JA 2IUCB 4LR7A 1KH5A 1KH4A 1FSUA 1KHJA 5GRRA 2W5VA 1K7HA 1AJAA 3IGYB 4LR8A 3WAVA 1E2SP 3M8ZA 3NKRA 3ED4A 3NKPA 4LRFA 1KHLA 4ZG6A 1EW2A 5EGHA 2X98A 3WAXA 2G9YA 3KD8A 4NWXA 5LRMA 1ELXA 3WAWA 4B56A 3UO0A 1E3CP 3SZYA 1AJBA 3UNYA 2W5QA 4LQYA 2RH6A 3BDGB 1ZEBA 3TX0A 2IUCA 4FDJA 3MK1A 2IFYA 2W5TA 3SZZA 3M8WA 1ALJA 5DLVA 3Q3QA 1ALIA 4FDIA 3M7VA 1EJJA 3TG0A 4CXSA 4MIVA 1ED9A 5LQQA 4MHXA 3E2DA 1N2LA 4KM4A 1AJCA 3LXQA 4LREA 5KXAA 3UN2A 4KJGA 4NWJA 4ZG9A 4LRCA 4QAXA 3NKOA 5GOVA 5LIAA 2W5XA 5DLTA 3BDHA 4UPIA 5HRTA 1KH7A 1URAA 2W5SA 1EW9A 5DLWA 2QZUA 2ZKTA 4GTZA 4N7TA 1AUKA 3WAYA 1ALHA 2GSOA 4LR9A 1ZEDA 4LRAA 3MK0A 3TWZA 4KAVA 4ZGAA 1URBA 1O98A 1EI6A 5K4PA 3T02A 3UN5A 5EGEA 2GA3A 3MK2A 4UPHA 4GTYA 1ANIA 3OT9A 1E1ZP 2W5RA 3T00A 3IGZB 5INHA 1KHNA 1Y7AA 3CMRA 2GLQA 2W8DA 3NVLA 3A52A 4UPKA 2GSUA 4MY4A 1EQJA 1SHQA 2XR9A 3WBHA 4GTWA 4UORA 5AJ9A 3T01A 4LR2A 1ANJA 1HJKA 4UOPA 3DPCA 5L0EA 1AJDA 4GTXA 4KAYA 2W5WA 1ALKA 3BDFA 2VQRA 4CXKA 1P49A 1EW8A 4CYRA 3B5QA 1E33P 5IJQA 5TJ3A 5LRNA 3IDDA 1KH9A 4UOOA 2ANHA 1O99A 2GSNA 2XRGA 4LRBA 1HQAA 1KHKA 1Y6VA 1ZEFA 3NKMA 4UPLA 3NKQA 2D1GA 4ZG7A 3BDGA 3UN3A 5L0KA 4KJDA 5C66A 1HDHA 3M8YA 1ED8A
chains in the Genus database with same CATH superfamily
3NKNA 5L0BA 4CXUA 3DYCA 4CYSA 4TN0A 1N2KA 1ELZA 5IJSA 4YR1A 1ELYA 1SHNA 2W8SA 4LRDA 1B8JA 2IUCB 4LR7A 1KH5A 1KH4A 1FSUA 1KHJA 5GRRA 2W5VA 1K7HA 1AJAA 3IGYB 4LR8A 3WAVA 1E2SP 3M8ZA 3NKRA 3ED4A 3NKPA 4LRFA 1KHLA 4ZG6A 1EW2A 5EGHA 2X98A 3WAXA 2G9YA 3KD8A 4NWXA 5LRMA 1ELXA 3WAWA 4B56A 3UO0A 1E3CP 3SZYA 1AJBA 3UNYA 2W5QA 4LQYA 2RH6A 3BDGB 1ZEBA 3TX0A 2IUCA 4FDJA 3MK1A 2IFYA 2W5TA 3SZZA 3M8WA 1ALJA 5DLVA 3Q3QA 1ALIA 4FDIA 3M7VA 1EJJA 3TG0A 4CXSA 4MIVA 1ED9A 5LQQA 4MHXA 3E2DA 1N2LA 4KM4A 1AJCA 3LXQA 4LREA 5KXAA 3UN2A 4KJGA 4NWJA 4ZG9A 4LRCA 4QAXA 3NKOA 5GOVA 5LIAA 2W5XA 5DLTA 3BDHA 4UPIA 5HRTA 1KH7A 1URAA 2W5SA 1EW9A 5DLWA 2QZUA 2ZKTA 4GTZA 4N7TA 1AUKA 3WAYA 1ALHA 2GSOA 4LR9A 1ZEDA 4LRAA 3MK0A 3TWZA 4KAVA 4ZGAA 1URBA 1O98A 1EI6A 5K4PA 3T02A 3UN5A 5EGEA 2GA3A 3MK2A 4UPHA 4GTYA 1ANIA 3OT9A 1E1ZP 2W5RA 3T00A 3IGZB 5INHA 1KHNA 1Y7AA 3CMRA 2GLQA 2W8DA 3NVLA 3A52A 4UPKA 2GSUA 4MY4A 1EQJA 1SHQA 2XR9A 3WBHA 4GTWA 4UORA 5AJ9A 3T01A 4LR2A 1ANJA 1HJKA 4UOPA 3DPCA 5L0EA 1AJDA 4GTXA 4KAYA 2W5WA 1ALKA 3BDFA 2VQRA 4CXKA 1P49A 1EW8A 4CYRA 3B5QA 1E33P 5IJQA 5TJ3A 5LRNA 3IDDA 1KH9A 4UOOA 2ANHA 1O99A 2GSNA 2XRGA 4LRBA 1HQAA 1KHKA 1Y6VA 1ZEFA 3NKMA 4UPLA 3NKQA 2D1GA 4ZG7A 3BDGA 3UN3A 5L0KA 4KJDA 5C66A 1HDHA 3M8YA 1ED8A
chains in the Genus database with same CATH topology
3NKNA 5L0BA 4CXUA 3DYCA 4CYSA 4TN0A 1N2KA 1ELZA 5IJSA 4YR1A 1ELYA 1SHNA 2W8SA 4LRDA 1B8JA 2IUCB 4LR7A 1KH5A 1KH4A 1FSUA 1KHJA 5GRRA 2W5VA 1K7HA 1AJAA 3IGYB 4LR8A 3WAVA 1E2SP 3M8ZA 3NKRA 3ED4A 3NKPA 4LRFA 1KHLA 4ZG6A 1EW2A 5EGHA 2X98A 3WAXA 2G9YA 3KD8A 4NWXA 5LRMA 1ELXA 3WAWA 4B56A 3UO0A 1E3CP 3SZYA 1AJBA 3UNYA 2W5QA 4LQYA 2RH6A 3BDGB 1ZEBA 3TX0A 2IUCA 4FDJA 3MK1A 2IFYA 2W5TA 3SZZA 3M8WA 1ALJA 5DLVA 3Q3QA 1ALIA 4FDIA 3M7VA 1EJJA 3TG0A 4CXSA 4MIVA 1ED9A 5LQQA 4MHXA 3E2DA 1N2LA 4KM4A 1AJCA 3LXQA 4LREA 5KXAA 3UN2A 4KJGA 4NWJA 4ZG9A 4LRCA 4QAXA 3NKOA 5GOVA 5LIAA 2W5XA 5DLTA 3BDHA 4UPIA 5HRTA 1KH7A 1URAA 2W5SA 1EW9A 5DLWA 2QZUA 2ZKTA 4GTZA 4N7TA 1AUKA 3WAYA 1ALHA 2GSOA 4LR9A 1ZEDA 4LRAA 3MK0A 3TWZA 4KAVA 4ZGAA 1URBA 1O98A 1EI6A 5K4PA 3T02A 3UN5A 5EGEA 2GA3A 3MK2A 4UPHA 4GTYA 1ANIA 3OT9A 1E1ZP 2W5RA 3T00A 3IGZB 5INHA 1KHNA 1Y7AA 3CMRA 2GLQA 2W8DA 3NVLA 3A52A 4UPKA 2GSUA 4MY4A 1EQJA 1SHQA 2XR9A 3WBHA 4GTWA 4UORA 5AJ9A 3T01A 4LR2A 1ANJA 1HJKA 4UOPA 3DPCA 5L0EA 1AJDA 4GTXA 4KAYA 2W5WA 1ALKA 3BDFA 2VQRA 4CXKA 1P49A 1EW8A 4CYRA 3B5QA 1E33P 5IJQA 5TJ3A 5LRNA 3IDDA 1KH9A 4UOOA 2ANHA 1O99A 2GSNA 2XRGA 4LRBA 1HQAA 1KHKA 1Y6VA 1ZEFA 3NKMA 4UPLA 3NKQA 2D1GA 4ZG7A 3BDGA 3UN3A 5L0KA 4KJDA 5C66A 1HDHA 3M8YA 1ED8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NKN A;  5L0B A;  4CXU A;  3DYC A;  4CYS A;  4TN0 A;  1N2K A;  1ELZ A;  5IJS A;  4YR1 A;  1ELY A;  1SHN A;  2W8S A;  4LRD A;  1B8J A;  2IUC B;  4LR7 A;  1KH5 A;  1KH4 A;  1FSU A;  1KHJ A;  5GRR A;  2W5V A;  1K7H A;  1AJA A;  3IGY B;  4LR8 A;  3WAV A;  1E2S P;  3M8Z A;  3NKR A;  3ED4 A;  3NKP A;  4LRF A;  1KHL A;  4ZG6 A;  1EW2 A;  5EGH A;  2X98 A;  3WAX A;  2G9Y A;  3KD8 A;  4NWX A;  5LRM A;  1ELX A;  3WAW A;  4B56 A;  3UO0 A;  1E3C P;  3SZY A;  1AJB A;  3UNY A;  2W5Q A;  4LQY A;  2RH6 A;  3BDG B;  1ZEB A;  3TX0 A;  2IUC A;  4FDJ A;  3MK1 A;  2IFY A;  2W5T A;  3SZZ A;  3M8W A;  1ALJ A;  5DLV A;  3Q3Q A;  1ALI A;  4FDI A;  3M7V A;  1EJJ A;  3TG0 A;  4CXS A;  4MIV A;  1ED9 A;  5LQQ A;  4MHX A;  3E2D A;  1N2L A;  4KM4 A;  1AJC A;  3LXQ A;  4LRE A;  5KXA A;  3UN2 A;  4KJG A;  4NWJ A;  4ZG9 A;  4LRC A;  4QAX A;  3NKO A;  5GOV A;  5LIA A;  2W5X A;  5DLT A;  3BDH A;  4UPI A;  5HRT A;  1KH7 A;  1URA A;  2W5S A;  1EW9 A;  5DLW A;  2QZU A;  2ZKT A;  4GTZ A;  4N7T A;  1AUK A;  3WAY A;  1ALH A;  2GSO A;  4LR9 A;  1ZED A;  4LRA A;  3MK0 A;  3TWZ A;  4KAV A;  4ZGA A;  1URB A;  1O98 A;  1EI6 A;  5K4P A;  3T02 A;  3UN5 A;  5EGE A;  2GA3 A;  3MK2 A;  4UPH A;  4GTY A;  1ANI A;  3OT9 A;  1E1Z P;  2W5R A;  3T00 A;  3IGZ B;  5INH A;  1KHN A;  1Y7A A;  3CMR A;  2GLQ A;  2W8D A;  3NVL A;  3A52 A;  4UPK A;  2GSU A;  4MY4 A;  1EQJ A;  1SHQ A;  2XR9 A;  3WBH A;  4GTW A;  4UOR A;  5AJ9 A;  3T01 A;  4LR2 A;  1ANJ A;  1HJK A;  4UOP A;  3DPC A;  5L0E A;  1AJD A;  4GTX A;  4KAY A;  2W5W A;  1ALK A;  3BDF A;  2VQR A;  4CXK A;  1P49 A;  1EW8 A;  4CYR A;  3B5Q A;  1E33 P;  5IJQ A;  5TJ3 A;  5LRN A;  3IDD A;  1KH9 A;  4UOO A;  2ANH A;  1O99 A;  2GSN A;  2XRG A;  4LRB A;  1HQA A;  1KHK A;  1Y6V A;  1ZEF A;  3NKM A;  4UPL A;  3NKQ A;  2D1G A;  4ZG7 A;  3BDG A;  3UN3 A;  5L0K A;  4KJD A;  5C66 A;  1HDH A;  3M8Y A;  1ED8 A; 
#chains in the Genus database with same CATH topology
 3NKN A;  5L0B A;  4CXU A;  3DYC A;  4CYS A;  4TN0 A;  1N2K A;  1ELZ A;  5IJS A;  4YR1 A;  1ELY A;  1SHN A;  2W8S A;  4LRD A;  1B8J A;  2IUC B;  4LR7 A;  1KH5 A;  1KH4 A;  1FSU A;  1KHJ A;  5GRR A;  2W5V A;  1K7H A;  1AJA A;  3IGY B;  4LR8 A;  3WAV A;  1E2S P;  3M8Z A;  3NKR A;  3ED4 A;  3NKP A;  4LRF A;  1KHL A;  4ZG6 A;  1EW2 A;  5EGH A;  2X98 A;  3WAX A;  2G9Y A;  3KD8 A;  4NWX A;  5LRM A;  1ELX A;  3WAW A;  4B56 A;  3UO0 A;  1E3C P;  3SZY A;  1AJB A;  3UNY A;  2W5Q A;  4LQY A;  2RH6 A;  3BDG B;  1ZEB A;  3TX0 A;  2IUC A;  4FDJ A;  3MK1 A;  2IFY A;  2W5T A;  3SZZ A;  3M8W A;  1ALJ A;  5DLV A;  3Q3Q A;  1ALI A;  4FDI A;  3M7V A;  1EJJ A;  3TG0 A;  4CXS A;  4MIV A;  1ED9 A;  5LQQ A;  4MHX A;  3E2D A;  1N2L A;  4KM4 A;  1AJC A;  3LXQ A;  4LRE A;  5KXA A;  3UN2 A;  4KJG A;  4NWJ A;  4ZG9 A;  4LRC A;  4QAX A;  3NKO A;  5GOV A;  5LIA A;  2W5X A;  5DLT A;  3BDH A;  4UPI A;  5HRT A;  1KH7 A;  1URA A;  2W5S A;  1EW9 A;  5DLW A;  2QZU A;  2ZKT A;  4GTZ A;  4N7T A;  1AUK A;  3WAY A;  1ALH A;  2GSO A;  4LR9 A;  1ZED A;  4LRA A;  3MK0 A;  3TWZ A;  4KAV A;  4ZGA A;  1URB A;  1O98 A;  1EI6 A;  5K4P A;  3T02 A;  3UN5 A;  5EGE A;  2GA3 A;  3MK2 A;  4UPH A;  4GTY A;  1ANI A;  3OT9 A;  1E1Z P;  2W5R A;  3T00 A;  3IGZ B;  5INH A;  1KHN A;  1Y7A A;  3CMR A;  2GLQ A;  2W8D A;  3NVL A;  3A52 A;  4UPK A;  2GSU A;  4MY4 A;  1EQJ A;  1SHQ A;  2XR9 A;  3WBH A;  4GTW A;  4UOR A;  5AJ9 A;  3T01 A;  4LR2 A;  1ANJ A;  1HJK A;  4UOP A;  3DPC A;  5L0E A;  1AJD A;  4GTX A;  4KAY A;  2W5W A;  1ALK A;  3BDF A;  2VQR A;  4CXK A;  1P49 A;  1EW8 A;  4CYR A;  3B5Q A;  1E33 P;  5IJQ A;  5TJ3 A;  5LRN A;  3IDD A;  1KH9 A;  4UOO A;  2ANH A;  1O99 A;  2GSN A;  2XRG A;  4LRB A;  1HQA A;  1KHK A;  1Y6V A;  1ZEF A;  3NKM A;  4UPL A;  3NKQ A;  2D1G A;  4ZG7 A;  3BDG A;  3UN3 A;  5L0K A;  4KJD A;  5C66 A;  1HDH A;  3M8Y A;  1ED8 A; 
#chains in the Genus database with same CATH homology
 3NKN A;  5L0B A;  4CXU A;  3DYC A;  4CYS A;  4TN0 A;  1N2K A;  1ELZ A;  5IJS A;  4YR1 A;  1ELY A;  1SHN A;  2W8S A;  4LRD A;  1B8J A;  2IUC B;  4LR7 A;  1KH5 A;  1KH4 A;  1FSU A;  1KHJ A;  5GRR A;  2W5V A;  1K7H A;  1AJA A;  3IGY B;  4LR8 A;  3WAV A;  1E2S P;  3M8Z A;  3NKR A;  3ED4 A;  3NKP A;  4LRF A;  1KHL A;  4ZG6 A;  1EW2 A;  5EGH A;  2X98 A;  3WAX A;  2G9Y A;  3KD8 A;  4NWX A;  5LRM A;  1ELX A;  3WAW A;  4B56 A;  3UO0 A;  1E3C P;  3SZY A;  1AJB A;  3UNY A;  2W5Q A;  4LQY A;  2RH6 A;  3BDG B;  1ZEB A;  3TX0 A;  2IUC A;  4FDJ A;  3MK1 A;  2IFY A;  2W5T A;  3SZZ A;  3M8W A;  1ALJ A;  5DLV A;  3Q3Q A;  1ALI A;  4FDI A;  3M7V A;  1EJJ A;  3TG0 A;  4CXS A;  4MIV A;  1ED9 A;  5LQQ A;  4MHX A;  3E2D A;  1N2L A;  4KM4 A;  1AJC A;  3LXQ A;  4LRE A;  5KXA A;  3UN2 A;  4KJG A;  4NWJ A;  4ZG9 A;  4LRC A;  4QAX A;  3NKO A;  5GOV A;  5LIA A;  2W5X A;  5DLT A;  3BDH A;  4UPI A;  5HRT A;  1KH7 A;  1URA A;  2W5S A;  1EW9 A;  5DLW A;  2QZU A;  2ZKT A;  4GTZ A;  4N7T A;  1AUK A;  3WAY A;  1ALH A;  2GSO A;  4LR9 A;  1ZED A;  4LRA A;  3MK0 A;  3TWZ A;  4KAV A;  4ZGA A;  1URB A;  1O98 A;  1EI6 A;  5K4P A;  3T02 A;  3UN5 A;  5EGE A;  2GA3 A;  3MK2 A;  4UPH A;  4GTY A;  1ANI A;  3OT9 A;  1E1Z P;  2W5R A;  3T00 A;  3IGZ B;  5INH A;  1KHN A;  1Y7A A;  3CMR A;  2GLQ A;  2W8D A;  3NVL A;  3A52 A;  4UPK A;  2GSU A;  4MY4 A;  1EQJ A;  1SHQ A;  2XR9 A;  3WBH A;  4GTW A;  4UOR A;  5AJ9 A;  3T01 A;  4LR2 A;  1ANJ A;  1HJK A;  4UOP A;  3DPC A;  5L0E A;  1AJD A;  4GTX A;  4KAY A;  2W5W A;  1ALK A;  3BDF A;  2VQR A;  4CXK A;  1P49 A;  1EW8 A;  4CYR A;  3B5Q A;  1E33 P;  5IJQ A;  5TJ3 A;  5LRN A;  3IDD A;  1KH9 A;  4UOO A;  2ANH A;  1O99 A;  2GSN A;  2XRG A;  4LRB A;  1HQA A;  1KHK A;  1Y6V A;  1ZEF A;  3NKM A;  4UPL A;  3NKQ A;  2D1G A;  4ZG7 A;  3BDG A;  3UN3 A;  5L0K A;  4KJD A;  5C66 A;  1HDH A;  3M8Y A;  1ED8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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