3NW8A

Glycoprotein b from herpes simplex virus type 1, y179s mutant, high-ph
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
622
structure length
607
Chain Sequence
DIKAENTDANFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRSSQFMGIFEDRAPVPFEEVIDKINAKGVCRSTAKYVRNNLETTAFHRDDHETDMELKPANAATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTSYAADRFKQVDGFYARDLTTKARATAPTTRNLLTTPKFTVAWDWVPKRPSVCTMTKWQEVDEMLRSEYGGSFRFSSDAISTTFTTNLTEYPLSRVDLGDCIGKDARDAMDRIFARRYNATHIKVGQPQYYLANGGFLIAYQPLLSNTLAELYVREHLREQSRKPVERIKTTSSIEFARLQFTYNHIQRHVNDMLGRVAIAWCELQNHELTLWNEARKLNPNAIASVTVGRRVSARMLGDVMAVSTCVPVAADNVIVQNSMRISSRPGACYSRPLVSFRYEDQGPLVEGQLGENNELRLTRDAIEPCTVGHRRYFTFGGGYVYFEEYAYSHQLSRADITTVSTFIDLNITMLEDHEFVPLEVYTRHEIKDSGLLDYTEVQRRNQLHDLRFADIDTVIH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1.
pubmed doi rcsb
molecule tags Viral protein
source organism Human herpesvirus 1
molecule keywords Envelope glycoprotein B
total genus 137
structure length 607
sequence length 622
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00606 Glycoprotein_B Herpesvirus Glycoprotein B ectodomain
A PF17416 Glycoprot_B_PH1 Herpesvirus Glycoprotein B
A PF17417 Glycoprot_B_PH2 Herpesvirus Glycoprotein B PH-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.100 Mainly Beta Roll PH-domain like PH-domain like 3nw8A03
3.30.1450.20 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 3nw8A01
3NWFA 4OT1A 4L1RA 3NWDA 2GUMA 3NWAA 4OSNA 4HSIA 3NW8A 3FVCA
chains in the Genus database with same CATH superfamily
5CLLB 3O96A 5J3TA 2J0KA 2ZPYA 2CODA 4GPTB 2QKMA 1EF1A 3KRXA 4KVGB 3T06A 2R2YA 2Z0PA 1FHWA 1V5PA 4KHBB 1FAOA 2D9YA 2K8EA 3A58A 1MIZB 2L1CA 2Z14A 1M7RA 3PEGA 2K00A 4CHJA 2GCLA 1V5UA 2I5FA 2G2WB 1H10A 4IAPA 3VOQA 1NTVA 2IFSA 2MDXA 5C5BA 1IRSA 1GG3A 5C79A 1SHCA 1P5TA 3HQCA 4F7GA 2W2XD 2EMTA 4HAVB 1ZSQA 3GYOA 3U12A 2P0HA 4HDQA 5KQ1A 3ML4A 4HAXB 1DDVA 4P7IA 3SO6A 4MY6A 4F7UP 4D6WA 3MDBC 1UNPA 3HK0A 5KQ4A 1TJ6A 2Z13A 2XQNM 5JHGA 1LB1A 4HB4B 4HHVA 1XKEA 5FI1A 2KIEA 2EMSA 4NY0A 1EVHA 3TO1A 2M38A 2P0FA 3NWFA 1KI1B 3OANA 2NMBA 4WSFA 2YS1A 2LOZA 3DXCA 5J3QA 1Y19B 1RRPB 2R09A 5JHHA 2DHIA 3KZ1A 2W2XC 4K81A 2NZ8B 5D3WA 4EKUA 3ULBA 1FHOA 1DDWA 2YSZA 2YRYA 5D0QE 3N7CA 1PMSA 3NWAA 3N4IB 3WYFB 3PP2A 3OHMB 3C4OB 4HAUB 4NSWA 5C16A 2G35A 1P6SA 4DX90 5LG4B 4PQ0A 3KSYA 4L6EA 3SUZA 2DYNA 5JLJB 1WVHA 5D3VA 2CRFA 3C7VB 4A6KA 3BINA 2MFQA 2Y8FA 4HB2B 4BBKA 3U8ZA 1ISNA 5EFXA 4KHOA 3ODOA 2COFA 1WG7A 2D9VA 3GYPA 4IFSA 3GMUB 2X18A 3D8FA 4MT7A 2DHJA 1H4RA 1X05A 3HW2B 5DHFB 4CHMA 5HE2A 4WJ7A 2ELBA 4A5KA 3IVFA 4DIXA 2LULA 2GS0A 2KUPA 5D3YA 2D9XA 2Y7BA 3A8PA 4QJ5B 5I2MA 3TCAA 2I5CA 2ELAA 1UNRA 4ZRIA 2CY5A 3SV1A 2PXGA 1B55A 3HSAA 3ODXA 3NWDA 5HE3A 2RGNB 1MK9B 2CY4A 3LJUX 2Y8GA 1Q67A 1MI1A 5C5BB 3QWMA 2J59M 2D10A 5I2SA 4HAYB 4MK0A 1QC6A 5DI9B 2P8VA 1V88A 3TW1A 3E2LC 2MKRA 3QBVB 2UZSA 5CLQB 3D8EA 2N23A 3DCXA 2DX1A 3AU4A 1X1FA 2YS5A 1EGXA 5EKQE 2H7EA 2RSGA 5KCVA 5JP4A 1X86A 1BTKA 2RNRB 3UZTA 3PZDA 1BAKA 4GZUA 2CAYA 4Z2NA 1DBHA 2DKQA 3ZDTA 2YT0A 2P0DA 2FJUB 1OQNA 3PSCA 5GOWB 3SYXA 3FM8C 3MPXA 2J0JA 1U5FA 1MPHA 5DIFB 1XR0B 2YS3A 4K2OA 2MWNB 2RUKB 2BCJA 1U2BA 1ZVRA 4B6HA 2GJYA 3A98B 2VSZA 4GMVA 2Z0OA 2D2QA 3C7UB 3ULCA 1U5EA 4OSNA 1QQGA 4ZRKA 2LOXA 5D27A 1ZC3B 2YT1A 2EJ8A 2Z0QA 4XWXA 1UPRA 2LKOA 3KRWA 1TQZA 3PVUA 2KIGA 1ZYIA 1U5GA 5DH9B 1MIXA 1K5GB 1XCGA 2VRWB 3PVLA 1Y5OA 1BWNA 1DDMA 4ZRJA 3P7ZA 4GXBA 3ODWA 2K49A 2UZRA 2DYQA 1S0WC 1XD4A 4L1RA 2NBVA 1WJ1A 1J0WA 3BJIA 3E2KC 4PNKA 2YF0A 1ZC4B 3KY9A 3M1IB 3AJ4A 1P3RA 2DFKA 3D4EA 4QJ3B 1SGHA 3TFMA 1GC6A 4K17A 3F0WA 4H8SA 2YVCA 2AEHA 2COCA 1UNQA 2N0YA 1TXDA 2L2IA 2V76A 4TYZA 2HTHB 4A6FA 2B5RC 2JP2A 3AU5A 5AYWE 2D11A 2H7DA 1RJ2A 2YT2A 1BTNA 2IYBA 4DXAB 1W1DA 2ZKMX 5M4YB 1UPQA 5D0OE 2J0MA 1AWEA 1V5MA 4YONA 2YH9A 2I1KA 5L81A 1PLSA 2E2XA 1V89A 5DHAB 4DBBA 1MK7B 1X1GA 1XODA 3CIKA 1WGQA 1DYNA 1W1HA 3NW8A 3C4PB 4HATB 2ROVA 1NU2A 1OMWA 4KHBA 4Z2MB 4HSIA 5C6RA 1W1GA 4IOYX 2UVMA 1FGYA 2I1JA 5HE0A 4DX8A 3D8DA 2RLOA 2PZ1A 1KZGA 3P6AA 4WVFB 4EJNA 1K5DB 4D0NB 4Y94A 4GMXB 2KCJA 3ZVRA 3RCPA 2D4QA 2DN6A 2KGXB 2DA0A 2Z59A 1N3HA 4HB0B 3DXEA 1Z87A 2KXXA 5LONB 5LOPB 1NTYA 2R0DA 4K2PA 1FOEA 4EMOA 4TKNA 1J19A 2ADZA 4YL8A 2LG1A 2FJLA 3A8QA 3DXDA 1XXMC 5FI0A 1MAIA 2AL6A 2HE7A 2OQBA 2COAA 2DKPA 1MKEA 2W2WA 3PVWA 2QKLA 3X23A 3QIJA 5HE1A 1WJMA 1M7EA 1FHXA 3CXBB 1FGZA 4C0AA 3G9WA 1EAZA 2KM7A 2Z4DA 4F7HA 2GUMA 2D9WA 4KHAA 3U7DA 1DROA 4QJ4B 1PFJA 3F5RA 1WGUA 1UEFA 3FEHA 4HB3B 4OT1A 1XX0A 2DLWA 1I2HA 3HIEA 4HAZB 4QXAB 3TVVA 2DHKA 2K2JA 2LYDA 2KR0A 2G2UB 2D9ZA 1U29A 2VKIA 5D3XA 1NI2A 4GOUA 1OY2A 2DX5A 4GN1A 1KZ7A 1U27A 1I7AA 1ZM0A 4CSQA 1U5DA 4CYEA 4GNKB 2RVBB 1JTGB 1T77A 5J3YA 3NSUA 3B77A 3WA0A 1X11A 1GC7A 2M14A 1V61A 4A6FB 4HDOA 2K2UA 3FSSA 5IRSA 4A6HA 1LW3A 3FVCA 2DTCA 2OTXA 4HAWB 2Q13A 2KUQA 1E5WA 1FB8A 3VIAA 3V5WA 2EC1A 2ROZB 1AQCA 3SNHA 4KAXB 2RRFA 1WI1A 2GCJA 4DM5A 3PG7A
chains in the Genus database with same CATH topology
5LG4B 4PQ0A 3C7UB 2Z59A 4OSNA 2KXXA 3C7VB 2R2YA 4KHBB 2K8EA 4KHOA 2KIGA 1ZYIA 3A58A 2Z14A 3GYPA 4IFSA 1XXMC 3GMUB 2GCLA 2G2WB 4DIXA 2K49A 1S0WC 4L1RA 2NBVA 4QJ5B 3E2KC 5I2MA 2KM7A 2Z4DA 2GUMA 3D4EA 4KHAA 4QJ3B 2PXGA 4QJ4B 3GYOA 3U12A 3NWDA 4D6WA 4OT1A 3HIEA 2Z13A 5I2SA 4QXAB 3TVVA 2KIEA 2B5RC 5AYWE 3TO1A 2KR0A 2YT2A 2G2UB 3NWFA 3TW1A 3E2LC 2ZKMX 5M4YB 4GOUA 5D0OE 2YH9A 4CSQA 4GNKB 1JTGB 5EKQE 4Z2NA 3FSSA 5IRSA 3NW8A 3FVCA 3C4PB 2FJUB 2KUQA 5D0QE 4KHBA 3NWAA 4Z2MB 4HSIA 3N4IB 4IOYX 3OHMB 3C4OB 2RRFA 2GCJA 4DM5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NWF A;  4OT1 A;  4L1R A;  3NWD A;  2GUM A;  3NWA A;  4OSN A;  4HSI A;  3NW8 A;  3FVC A; 
#chains in the Genus database with same CATH topology
 5CLL B;  3O96 A;  5J3T A;  2J0K A;  2ZPY A;  2COD A;  4GPT B;  2QKM A;  1EF1 A;  3KRX A;  4KVG B;  3T06 A;  2R2Y A;  2Z0P A;  1FHW A;  1V5P A;  4KHB B;  1FAO A;  2D9Y A;  2K8E A;  3A58 A;  1MIZ B;  2L1C A;  2Z14 A;  1M7R A;  3PEG A;  2K00 A;  4CHJ A;  2GCL A;  1V5U A;  2I5F A;  2G2W B;  1H10 A;  4IAP A;  3VOQ A;  1NTV A;  2IFS A;  2MDX A;  5C5B A;  1IRS A;  1GG3 A;  5C79 A;  1SHC A;  1P5T A;  3HQC A;  4F7G A;  2W2X D;  2EMT A;  4HAV B;  1ZSQ A;  3GYO A;  3U12 A;  2P0H A;  4HDQ A;  5KQ1 A;  3ML4 A;  4HAX B;  1DDV A;  4P7I A;  3SO6 A;  4MY6 A;  4F7U P;  4D6W A;  3MDB C;  1UNP A;  3HK0 A;  5KQ4 A;  1TJ6 A;  2Z13 A;  2XQN M;  5JHG A;  1LB1 A;  4HB4 B;  4HHV A;  1XKE A;  5FI1 A;  2KIE A;  2EMS A;  4NY0 A;  1EVH A;  3TO1 A;  2M38 A;  2P0F A;  3NWF A;  1KI1 B;  3OAN A;  2NMB A;  4WSF A;  2YS1 A;  2LOZ A;  3DXC A;  5J3Q A;  1Y19 B;  1RRP B;  2R09 A;  5JHH A;  2DHI A;  3KZ1 A;  2W2X C;  4K81 A;  2NZ8 B;  5D3W A;  4EKU A;  3ULB A;  1FHO A;  1DDW A;  2YSZ A;  2YRY A;  5D0Q E;  3N7C A;  1PMS A;  3NWA A;  3N4I B;  3WYF B;  3PP2 A;  3OHM B;  3C4O B;  4HAU B;  4NSW A;  5C16 A;  2G35 A;  1P6S A;  4DX9 0;  5LG4 B;  4PQ0 A;  3KSY A;  4L6E A;  3SUZ A;  2DYN A;  5JLJ B;  1WVH A;  5D3V A;  2CRF A;  3C7V B;  4A6K A;  3BIN A;  2MFQ A;  2Y8F A;  4HB2 B;  4BBK A;  3U8Z A;  1ISN A;  5EFX A;  4KHO A;  3ODO A;  2COF A;  1WG7 A;  2D9V A;  3GYP A;  4IFS A;  3GMU B;  2X18 A;  3D8F A;  4MT7 A;  2DHJ A;  1H4R A;  1X05 A;  3HW2 B;  5DHF B;  4CHM A;  5HE2 A;  4WJ7 A;  2ELB A;  4A5K A;  3IVF A;  4DIX A;  2LUL A;  2GS0 A;  2KUP A;  5D3Y A;  2D9X A;  2Y7B A;  3A8P A;  4QJ5 B;  5I2M A;  3TCA A;  2I5C A;  2ELA A;  1UNR A;  4ZRI A;  2CY5 A;  3SV1 A;  2PXG A;  1B55 A;  3HSA A;  3ODX A;  3NWD A;  5HE3 A;  2RGN B;  1MK9 B;  2CY4 A;  3LJU X;  2Y8G A;  1Q67 A;  1MI1 A;  5C5B B;  3QWM A;  2J59 M;  2D10 A;  5I2S A;  4HAY B;  4MK0 A;  1QC6 A;  5DI9 B;  2P8V A;  1V88 A;  3TW1 A;  3E2L C;  2MKR A;  3QBV B;  2UZS A;  5CLQ B;  3D8E A;  2N23 A;  3DCX A;  2DX1 A;  3AU4 A;  1X1F A;  2YS5 A;  1EGX A;  5EKQ E;  2H7E A;  2RSG A;  5KCV A;  5JP4 A;  1X86 A;  1BTK A;  2RNR B;  3UZT A;  3PZD A;  1BAK A;  4GZU A;  2CAY A;  4Z2N A;  1DBH A;  2DKQ A;  3ZDT A;  2YT0 A;  2P0D A;  2FJU B;  1OQN A;  3PSC A;  5GOW B;  3SYX A;  3FM8 C;  3MPX A;  2J0J A;  1U5F A;  1MPH A;  5DIF B;  1XR0 B;  2YS3 A;  4K2O A;  2MWN B;  2RUK B;  2BCJ A;  1U2B A;  1ZVR A;  4B6H A;  2GJY A;  3A98 B;  2VSZ A;  4GMV A;  2Z0O A;  2D2Q A;  3C7U B;  3ULC A;  1U5E A;  4OSN A;  1QQG A;  4ZRK A;  2LOX A;  5D27 A;  1ZC3 B;  2YT1 A;  2EJ8 A;  2Z0Q A;  4XWX A;  1UPR A;  2LKO A;  3KRW A;  1TQZ A;  3PVU A;  2KIG A;  1ZYI A;  1U5G A;  5DH9 B;  1MIX A;  1K5G B;  1XCG A;  2VRW B;  3PVL A;  1Y5O A;  1BWN A;  1DDM A;  4ZRJ A;  3P7Z A;  4GXB A;  3ODW A;  2K49 A;  2UZR A;  2DYQ A;  1S0W C;  1XD4 A;  4L1R A;  2NBV A;  1WJ1 A;  1J0W A;  3BJI A;  3E2K C;  4PNK A;  2YF0 A;  1ZC4 B;  3KY9 A;  3M1I B;  3AJ4 A;  1P3R A;  2DFK A;  3D4E A;  4QJ3 B;  1SGH A;  3TFM A;  1GC6 A;  4K17 A;  3F0W A;  4H8S A;  2YVC A;  2AEH A;  2COC A;  1UNQ A;  2N0Y A;  1TXD A;  2L2I A;  2V76 A;  4TYZ A;  2HTH B;  4A6F A;  2B5R C;  2JP2 A;  3AU5 A;  5AYW E;  2D11 A;  2H7D A;  1RJ2 A;  2YT2 A;  1BTN A;  2IYB A;  4DXA B;  1W1D A;  2ZKM X;  5M4Y B;  1UPQ A;  5D0O E;  2J0M A;  1AWE A;  1V5M A;  4YON A;  2YH9 A;  2I1K A;  5L81 A;  1PLS A;  2E2X A;  1V89 A;  5DHA B;  4DBB A;  1MK7 B;  1X1G A;  1XOD A;  3CIK A;  1WGQ A;  1DYN A;  1W1H A;  3NW8 A;  3C4P B;  4HAT B;  2ROV A;  1NU2 A;  1OMW A;  4KHB A;  4Z2M B;  4HSI A;  5C6R A;  1W1G A;  4IOY X;  2UVM A;  1FGY A;  2I1J A;  5HE0 A;  4DX8 A;  3D8D A;  2RLO A;  2PZ1 A;  1KZG A;  3P6A A;  4WVF B;  4EJN A;  1K5D B;  4D0N B;  4Y94 A;  4GMX B;  2KCJ A;  3ZVR A;  3RCP A;  2D4Q A;  2DN6 A;  2KGX B;  2DA0 A;  2Z59 A;  1N3H A;  4HB0 B;  3DXE A;  1Z87 A;  2KXX A;  5LON B;  5LOP B;  1NTY A;  2R0D A;  4K2P A;  1FOE A;  4EMO A;  4TKN A;  1J19 A;  2ADZ A;  4YL8 A;  2LG1 A;  2FJL A;  3A8Q A;  3DXD A;  1XXM C;  5FI0 A;  1MAI A;  2AL6 A;  2HE7 A;  2OQB A;  2COA A;  2DKP A;  1MKE A;  2W2W A;  3PVW A;  2QKL A;  3X23 A;  3QIJ A;  5HE1 A;  1WJM A;  1M7E A;  1FHX A;  3CXB B;  1FGZ A;  4C0A A;  3G9W A;  1EAZ A;  2KM7 A;  2Z4D A;  4F7H A;  2GUM A;  2D9W A;  4KHA A;  3U7D A;  1DRO A;  4QJ4 B;  1PFJ A;  3F5R A;  1WGU A;  1UEF A;  3FEH A;  4HB3 B;  4OT1 A;  1XX0 A;  2DLW A;  1I2H A;  3HIE A;  4HAZ B;  4QXA B;  3TVV A;  2DHK A;  2K2J A;  2LYD A;  2KR0 A;  2G2U B;  2D9Z A;  1U29 A;  2VKI A;  5D3X A;  1NI2 A;  4GOU A;  1OY2 A;  2DX5 A;  4GN1 A;  1KZ7 A;  1U27 A;  1I7A A;  1ZM0 A;  4CSQ A;  1U5D A;  4CYE A;  4GNK B;  2RVB B;  1JTG B;  1T77 A;  5J3Y A;  3NSU A;  3B77 A;  3WA0 A;  1X11 A;  1GC7 A;  2M14 A;  1V61 A;  4A6F B;  4HDO A;  2K2U A;  3FSS A;  5IRS A;  4A6H A;  1LW3 A;  3FVC A;  2DTC A;  2OTX A;  4HAW B;  2Q13 A;  2KUQ A;  1E5W A;  1FB8 A;  3VIA A;  3V5W A;  2EC1 A;  2ROZ B;  1AQC A;  3SNH A;  4KAX B;  2RRF A;  1WI1 A;  2GCJ A;  4DM5 A;  3PG7 A; 
#chains in the Genus database with same CATH homology
 5LG4 B;  4PQ0 A;  3C7U B;  2Z59 A;  4OSN A;  2KXX A;  3C7V B;  2R2Y A;  4KHB B;  2K8E A;  4KHO A;  2KIG A;  1ZYI A;  3A58 A;  2Z14 A;  3GYP A;  4IFS A;  1XXM C;  3GMU B;  2GCL A;  2G2W B;  4DIX A;  2K49 A;  1S0W C;  4L1R A;  2NBV A;  4QJ5 B;  3E2K C;  5I2M A;  2KM7 A;  2Z4D A;  2GUM A;  3D4E A;  4KHA A;  4QJ3 B;  2PXG A;  4QJ4 B;  3GYO A;  3U12 A;  3NWD A;  4D6W A;  4OT1 A;  3HIE A;  2Z13 A;  5I2S A;  4QXA B;  3TVV A;  2KIE A;  2B5R C;  5AYW E;  3TO1 A;  2KR0 A;  2YT2 A;  2G2U B;  3NWF A;  3TW1 A;  3E2L C;  2ZKM X;  5M4Y B;  4GOU A;  5D0O E;  2YH9 A;  4CSQ A;  4GNK B;  1JTG B;  5EKQ E;  4Z2N A;  3FSS A;  5IRS A;  3NW8 A;  3FVC A;  3C4P B;  2FJU B;  2KUQ A;  5D0Q E;  4KHB A;  3NWA A;  4Z2M B;  4HSI A;  3N4I B;  4IOY X;  3OHM B;  3C4O B;  2RRF A;  2GCJ A;  4DM5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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