3NWAA

Glycoprotein b from herpes simplex virus type 1, w174r mutant, low-ph
Total Genus 146
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
622
structure length
608
Chain Sequence
DIKAENTDANFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVRFGHRYSQFMGIFEDRAPVPFEEVIDKINAKGVCRSTAKYVRNNLETTAFHRDDHETDMELKPANAATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTSYAADRFKQVDGFYARDLTTKARATAPTTRNLLTTPKFTVAWDWVPKRPSVCTMTKWQEVDEMLRSEYGGSFRFSSDAISTTFTTNLTEYPLSRVDLGDCIGKDARDAMDRIFARRYNATHIKVGQPQYYLANGGFLIAYQPLLSNTLAELYVREHLREQSRKPPVERIKTTSSIEFARLQFTYNHIQRHVNDMLGRVAIAWCELQNHELTLWNEARKLNPNAIASVTVGRRVSARMLGDVMAVSTCVPVAADNVIVQNSMRISSRPGACYSRPLVSFRYEDQGPLVEGQLGENNELRLTRDAIEPCTVGHRRYFTFGGGYVYFEEYAYSHQLSRADITTVSTFIDLNITMLEDHEFVPLEVYTRHEIKDSGLLDYTEVQRRNQLHDLRFADIDTVIH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1.
pubmed doi rcsb
molecule tags Viral protein
source organism Human herpesvirus 1
molecule keywords Envelope glycoprotein B
total genus 146
structure length 608
sequence length 622
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00606 Glycoprotein_B Herpesvirus Glycoprotein B ectodomain
A PF17416 Glycoprot_B_PH1 Herpesvirus Glycoprotein B
A PF17417 Glycoprot_B_PH2 Herpesvirus Glycoprotein B PH-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.100 Mainly Beta Roll PH-domain like PH-domain like 3nwaA03
3.30.1450.20 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 3nwaA01
4OSNA 3FVCA 3NWFA 4OT1A 3NW8A 3NWDA 3NWAA 2GUMA 4L1RA 4HSIA
chains in the Genus database with same CATH superfamily
1H4RA 2ADZA 2D11A 5I2SA 1DDWA 5IRSA 3WYFB 1WJMA 2YT2A 4CYEA 2DHIA 1TQZA 3BINA 3VIAA 1OMWA 3AJ4A 2P0FA 4P7IA 2K00A 5C6RA 1U5DA 3SO6A 2Z0QA 3OANA 3P6AA 1SHCA 2P0HA 2RLOA 5LOPB 4EJNA 3T06A 1FAOA 2OQBA 2RVBB 4L1RA 1W1HA 1SGHA 2J0JA 2VKIA 1X05A 1OQNA 4Z2NA 2RSGA 3NSUA 1V61A 1PMSA 3QBVB 1KZGA 2MDXA 1WI1A 5J3TA 4HHVA 4GN1A 5I2MA 4B6HA 1XX0A 4MK0A 3KZ1A 1X11A 2DX5A 2GCJA 2DN6A 2J0MA 2P8VA 3G9WA 1W1DA 3ODXA 2D4QA 3HQCA 3FEHA 2D10A 2RGNB 4K81A 4MT7A 1Y5OA 1Y19B 2MWNB 2LYDA 2Y7BA 3PVUA 2COFA 2KUPA 3FSSA 2J59M 3GYPA 2Z0PA 2COCA 4NY0A 3NWDA 2FJUB 2YS3A 4L6EA 4D6WA 5HE3A 2KUQA 1XODA 2D9ZA 5D3WA 3SNHA 1U27A 1RJ2A 2YVCA 3A8PA 1MKEA 5EFXA 2LOXA 1FHWA 4A6KA 1TXDA 1Z87A 4Z2MB 3FVCA 1FOEA 2DX1A 2CODA 2EMSA 4HB2B 4IFSA 2Q13A 1ZSQA 2CAYA 2YRYA 2GS0A 1UPQA 3ULCA 2Z59A 3C7VB 1MK7B 4DBBA 4KHAA 3N7CA 2DHJA 3QIJA 5AYWE 2Z13A 2JP2A 2ROZB 1QQGA 2ZPYA 4CHJA 1GC7A 1FHXA 5GOWB 2YS5A 3VOQA 4KAXB 2D9WA 4ZRJA 5C5BA 2CRFA 4EMOA 3HW2B 1AWEA 1ZVRA 2G35A 3OHMB 2RRFA 3ML4A 1ISNA 4HAWB 3F0WA 3RCPA 2Z0OA 4GMXB 4HB4B 4OT1A 1DDMA 2YT0A 3D8EA 4EKUA 2EMTA 2ELAA 4NSWA 2AEHA 2IYBA 1X86A 2DLWA 4IOYX 1BTNA 3FM8C 2W2XC 2D2QA 1M7EA 1OY2A 4GXBA 4QJ4B 1BAKA 3PEGA 4A5KA 2K2UA 2KGXB 2BCJA 4WVFB 4D0NB 2QKMA 4QJ3B 5FI1A 5CLQB 1V89A 5DIFB 2EJ8A 5JLJB 1KI1B 3C4PB 5D0QE 2P0DA 3NWFA 1DYNA 2NBVA 4HAXB 2CY4A 1K5DB 2IFSA 1GC6A 3TO1A 3KSYA 4GZUA 1RRPB 4WSFA 5JHHA 1LW3A 2KXXA 3SV1A 4HB0B 2GJYA 1UNRA 2DA0A 1FGZA 4GMVA 1E5WA 2R2YA 2G2UB 2D9XA 5EKQE 2LULA 1UNQA 4A6FA 3NW8A 3DXCA 2AL6A 4K2OA 3WA0A 3LJUX 3GYOA 5DHAB 5C5BB 5HE1A 5KQ1A 3C7UB 3SYXA 2FJLA 3PVLA 3MDBC 3V5WA 3PG7A 3BJIA 4PNKA 3A98B 2KIEA 2DKQA 4K17A 5D27A 1NI2A 4HDQA 2RNRB 5C16A 5HE2A 3SUZA 1U29A 1T77A 4TKNA 1J19A 2V76A 2W2WA 5D3VA 2D9YA 2Y8GA 3D8FA 2LKOA 3PZDA 3P7ZA 2CY5A 1EVHA 4ZRIA 2N0YA 1MI1A 1Q67A 2YF0A 4KHBA 4QXAB 2J0KA 2YT1A 1IRSA 3TW1A 4KHOA 2H7EA 2DYQA 2YS1A 3PP2A 2GCLA 1J0WA 2HTHB 2OTXA 3CXBB 4YONA 4HAVB 2Z4DA 3HIEA 1DBHA 1P3RA 2Z14A 4A6HA 3PVWA 3KRXA 2YSZA 5J3YA 5M4YB 3E2LC 3N4IB 1I7AA 1LB1A 1UPRA 2DKPA 4DM5A 5DI9B 3ODOA 1FHOA 1V88A 1DDVA 3F5RA 4DX90 5J3QA 1XD4A 2NMBA 4GPTB 2XQNM 1NU2A 5JHGA 4DIXA 1ZC3B 2K49A 1U2BA 2M38A 1EGXA 3ULBA 4A6FB 4DX8A 5LONB 4OSNA 1DROA 1WGUA 1WG7A 4TYZA 2MFQA 5HE0A 5C79A 2G2WB 1AQCA 1EF1A 1NTYA 1XR0B 3DXEA 2DYNA 1H10A 5DH9B 2ELBA 3X23A 1S0WC 4GOUA 4PQ0A 1PLSA 4ZRKA 2KR0A 5KQ4A 4HAZB 3O96A 5LG4B 2UZRA 2LOZA 2R09A 1B55A 1PFJA 1BWNA 4Y94A 3GMUB 1FGYA 1V5MA 3M1IB 2KM7A 2Y8FA 3IVFA 2LG1A 5D3YA 1U5EA 2HE7A 2NZ8B 4KHBB 2I5FA 4HSIA 4F7UP 1MIXA 2ROVA 3A8QA 1NTVA 1EAZA 4HDOA 3TFMA 2N23A 1XCGA 2W2XD 1M7RA 2K2JA 2DTCA 2COAA 2DHKA 3HSAA 2KIGA 1P6SA 5JP4A 4CHMA 2B5RC 2E2XA 2PXGA 1WJ1A 1UNPA 1I2HA 4K2PA 2I1JA 2H7DA 4IAPA 5L81A 1ZC4B 2L2IA 4HAYB 3A58A 1WVHA 2VRWB 4MY6A 2GUMA 3AU5A 4YL8A 3C4OB 2I1KA 2DFKA 1X1FA 3CIKA 3PSCA 1QC6A 1U5FA 2ZKMX 2L1CA 2QKLA 3UZTA 1N3HA 3U7DA 1MPHA 4C0AA 2PZ1A 3ZDTA 1P5TA 2K8EA 1MIZB 3AU4A 1V5PA 3TCAA 2M14A 4H8SA 3QWMA 4HAUB 3D8DA 1V5UA 4BBKA 1KZ7A 3E2KC 1GG3A 3DXDA 1UEFA 2I5CA 1XXMC 5D0OE 1U5GA 2UVMA 3KY9A 3U8ZA 1JTGB 3D4EA 1ZYIA 3ZVRA 3ODWA 5D3XA 4DXAB 4F7HA 1TJ6A 4GNKB 2D9VA 3U12A 3TVVA 4KVGB 5CLLB 1X1GA 5KCVA 2EC1A 3MPXA 3B77A 2RUKB 4WJ7A 4QJ5B 1MAIA 1FB8A 1MK9B 2KCJA 2R0DA 5FI0A 2MKRA 4HATB 2UZSA 1W1GA 3HK0A 2VSZA 4HB3B 5DHFB 3NWAA 4F7GA 2X18A 3DCXA 1WGQA 3KRWA 1XKEA 2YH9A 4XWXA 1BTKA 1K5GB 1ZM0A 4CSQA
chains in the Genus database with same CATH topology
5I2SA 5IRSA 2YT2A 2KIGA 2B5RC 2PXGA 4KHBA 4QXAB 3TW1A 3OHMB 2RRFA 4KHOA 4L1RA 3A58A 4OT1A 2GCLA 2GUMA 4Z2NA 2Z4DA 3HIEA 2Z14A 3C4OB 4IOYX 5M4YB 3E2LC 3N4IB 5I2MA 2ZKMX 4DM5A 4QJ4B 2GCJA 2K8EA 4QJ3B 3C4PB 4DIXA 5D0QE 3NWFA 2K49A 2NBVA 3FSSA 3E2KC 4OSNA 3TO1A 3GYPA 3NWDA 2FJUB 5D0OE 1XXMC 2G2WB 2KXXA 1JTGB 3D4EA 4D6WA 1ZYIA 2KUQA 1S0WC 4GOUA 4PQ0A 4GNKB 2R2YA 2KR0A 2G2UB 3U12A 3TVVA 5EKQE 4Z2MB 3FVCA 5LG4B 3NW8A 4QJ5B 4IFSA 3GMUB 3GYOA 2Z59A 2KM7A 3C7VB 3C7UB 4KHAA 3NWAA 4KHBB 4HSIA 5AYWE 2YH9A 2KIEA 2Z13A 4CSQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OSN A;  3FVC A;  3NWF A;  4OT1 A;  3NW8 A;  3NWD A;  3NWA A;  2GUM A;  4L1R A;  4HSI A; 
#chains in the Genus database with same CATH topology
 1H4R A;  2ADZ A;  2D11 A;  5I2S A;  1DDW A;  5IRS A;  3WYF B;  1WJM A;  2YT2 A;  4CYE A;  2DHI A;  1TQZ A;  3BIN A;  3VIA A;  1OMW A;  3AJ4 A;  2P0F A;  4P7I A;  2K00 A;  5C6R A;  1U5D A;  3SO6 A;  2Z0Q A;  3OAN A;  3P6A A;  1SHC A;  2P0H A;  2RLO A;  5LOP B;  4EJN A;  3T06 A;  1FAO A;  2OQB A;  2RVB B;  4L1R A;  1W1H A;  1SGH A;  2J0J A;  2VKI A;  1X05 A;  1OQN A;  4Z2N A;  2RSG A;  3NSU A;  1V61 A;  1PMS A;  3QBV B;  1KZG A;  2MDX A;  1WI1 A;  5J3T A;  4HHV A;  4GN1 A;  5I2M A;  4B6H A;  1XX0 A;  4MK0 A;  3KZ1 A;  1X11 A;  2DX5 A;  2GCJ A;  2DN6 A;  2J0M A;  2P8V A;  3G9W A;  1W1D A;  3ODX A;  2D4Q A;  3HQC A;  3FEH A;  2D10 A;  2RGN B;  4K81 A;  4MT7 A;  1Y5O A;  1Y19 B;  2MWN B;  2LYD A;  2Y7B A;  3PVU A;  2COF A;  2KUP A;  3FSS A;  2J59 M;  3GYP A;  2Z0P A;  2COC A;  4NY0 A;  3NWD A;  2FJU B;  2YS3 A;  4L6E A;  4D6W A;  5HE3 A;  2KUQ A;  1XOD A;  2D9Z A;  5D3W A;  3SNH A;  1U27 A;  1RJ2 A;  2YVC A;  3A8P A;  1MKE A;  5EFX A;  2LOX A;  1FHW A;  4A6K A;  1TXD A;  1Z87 A;  4Z2M B;  3FVC A;  1FOE A;  2DX1 A;  2COD A;  2EMS A;  4HB2 B;  4IFS A;  2Q13 A;  1ZSQ A;  2CAY A;  2YRY A;  2GS0 A;  1UPQ A;  3ULC A;  2Z59 A;  3C7V B;  1MK7 B;  4DBB A;  4KHA A;  3N7C A;  2DHJ A;  3QIJ A;  5AYW E;  2Z13 A;  2JP2 A;  2ROZ B;  1QQG A;  2ZPY A;  4CHJ A;  1GC7 A;  1FHX A;  5GOW B;  2YS5 A;  3VOQ A;  4KAX B;  2D9W A;  4ZRJ A;  5C5B A;  2CRF A;  4EMO A;  3HW2 B;  1AWE A;  1ZVR A;  2G35 A;  3OHM B;  2RRF A;  3ML4 A;  1ISN A;  4HAW B;  3F0W A;  3RCP A;  2Z0O A;  4GMX B;  4HB4 B;  4OT1 A;  1DDM A;  2YT0 A;  3D8E A;  4EKU A;  2EMT A;  2ELA A;  4NSW A;  2AEH A;  2IYB A;  1X86 A;  2DLW A;  4IOY X;  1BTN A;  3FM8 C;  2W2X C;  2D2Q A;  1M7E A;  1OY2 A;  4GXB A;  4QJ4 B;  1BAK A;  3PEG A;  4A5K A;  2K2U A;  2KGX B;  2BCJ A;  4WVF B;  4D0N B;  2QKM A;  4QJ3 B;  5FI1 A;  5CLQ B;  1V89 A;  5DIF B;  2EJ8 A;  5JLJ B;  1KI1 B;  3C4P B;  5D0Q E;  2P0D A;  3NWF A;  1DYN A;  2NBV A;  4HAX B;  2CY4 A;  1K5D B;  2IFS A;  1GC6 A;  3TO1 A;  3KSY A;  4GZU A;  1RRP B;  4WSF A;  5JHH A;  1LW3 A;  2KXX A;  3SV1 A;  4HB0 B;  2GJY A;  1UNR A;  2DA0 A;  1FGZ A;  4GMV A;  1E5W A;  2R2Y A;  2G2U B;  2D9X A;  5EKQ E;  2LUL A;  1UNQ A;  4A6F A;  3NW8 A;  3DXC A;  2AL6 A;  4K2O A;  3WA0 A;  3LJU X;  3GYO A;  5DHA B;  5C5B B;  5HE1 A;  5KQ1 A;  3C7U B;  3SYX A;  2FJL A;  3PVL A;  3MDB C;  3V5W A;  3PG7 A;  3BJI A;  4PNK A;  3A98 B;  2KIE A;  2DKQ A;  4K17 A;  5D27 A;  1NI2 A;  4HDQ A;  2RNR B;  5C16 A;  5HE2 A;  3SUZ A;  1U29 A;  1T77 A;  4TKN A;  1J19 A;  2V76 A;  2W2W A;  5D3V A;  2D9Y A;  2Y8G A;  3D8F A;  2LKO A;  3PZD A;  3P7Z A;  2CY5 A;  1EVH A;  4ZRI A;  2N0Y A;  1MI1 A;  1Q67 A;  2YF0 A;  4KHB A;  4QXA B;  2J0K A;  2YT1 A;  1IRS A;  3TW1 A;  4KHO A;  2H7E A;  2DYQ A;  2YS1 A;  3PP2 A;  2GCL A;  1J0W A;  2HTH B;  2OTX A;  3CXB B;  4YON A;  4HAV B;  2Z4D A;  3HIE A;  1DBH A;  1P3R A;  2Z14 A;  4A6H A;  3PVW A;  3KRX A;  2YSZ A;  5J3Y A;  5M4Y B;  3E2L C;  3N4I B;  1I7A A;  1LB1 A;  1UPR A;  2DKP A;  4DM5 A;  5DI9 B;  3ODO A;  1FHO A;  1V88 A;  1DDV A;  3F5R A;  4DX9 0;  5J3Q A;  1XD4 A;  2NMB A;  4GPT B;  2XQN M;  1NU2 A;  5JHG A;  4DIX A;  1ZC3 B;  2K49 A;  1U2B A;  2M38 A;  1EGX A;  3ULB A;  4A6F B;  4DX8 A;  5LON B;  4OSN A;  1DRO A;  1WGU A;  1WG7 A;  4TYZ A;  2MFQ A;  5HE0 A;  5C79 A;  2G2W B;  1AQC A;  1EF1 A;  1NTY A;  1XR0 B;  3DXE A;  2DYN A;  1H10 A;  5DH9 B;  2ELB A;  3X23 A;  1S0W C;  4GOU A;  4PQ0 A;  1PLS A;  4ZRK A;  2KR0 A;  5KQ4 A;  4HAZ B;  3O96 A;  5LG4 B;  2UZR A;  2LOZ A;  2R09 A;  1B55 A;  1PFJ A;  1BWN A;  4Y94 A;  3GMU B;  1FGY A;  1V5M A;  3M1I B;  2KM7 A;  2Y8F A;  3IVF A;  2LG1 A;  5D3Y A;  1U5E A;  2HE7 A;  2NZ8 B;  4KHB B;  2I5F A;  4HSI A;  4F7U P;  1MIX A;  2ROV A;  3A8Q A;  1NTV A;  1EAZ A;  4HDO A;  3TFM A;  2N23 A;  1XCG A;  2W2X D;  1M7R A;  2K2J A;  2DTC A;  2COA A;  2DHK A;  3HSA A;  2KIG A;  1P6S A;  5JP4 A;  4CHM A;  2B5R C;  2E2X A;  2PXG A;  1WJ1 A;  1UNP A;  1I2H A;  4K2P A;  2I1J A;  2H7D A;  4IAP A;  5L81 A;  1ZC4 B;  2L2I A;  4HAY B;  3A58 A;  1WVH A;  2VRW B;  4MY6 A;  2GUM A;  3AU5 A;  4YL8 A;  3C4O B;  2I1K A;  2DFK A;  1X1F A;  3CIK A;  3PSC A;  1QC6 A;  1U5F A;  2ZKM X;  2L1C A;  2QKL A;  3UZT A;  1N3H A;  3U7D A;  1MPH A;  4C0A A;  2PZ1 A;  3ZDT A;  1P5T A;  2K8E A;  1MIZ B;  3AU4 A;  1V5P A;  3TCA A;  2M14 A;  4H8S A;  3QWM A;  4HAU B;  3D8D A;  1V5U A;  4BBK A;  1KZ7 A;  3E2K C;  1GG3 A;  3DXD A;  1UEF A;  2I5C A;  1XXM C;  5D0O E;  1U5G A;  2UVM A;  3KY9 A;  3U8Z A;  1JTG B;  3D4E A;  1ZYI A;  3ZVR A;  3ODW A;  5D3X A;  4DXA B;  4F7H A;  1TJ6 A;  4GNK B;  2D9V A;  3U12 A;  3TVV A;  4KVG B;  5CLL B;  1X1G A;  5KCV A;  2EC1 A;  3MPX A;  3B77 A;  2RUK B;  4WJ7 A;  4QJ5 B;  1MAI A;  1FB8 A;  1MK9 B;  2KCJ A;  2R0D A;  5FI0 A;  2MKR A;  4HAT B;  2UZS A;  1W1G A;  3HK0 A;  2VSZ A;  4HB3 B;  5DHF B;  3NWA A;  4F7G A;  2X18 A;  3DCX A;  1WGQ A;  3KRW A;  1XKE A;  2YH9 A;  4XWX A;  1BTK A;  1K5G B;  1ZM0 A;  4CSQ A; 
#chains in the Genus database with same CATH homology
 5I2S A;  5IRS A;  2YT2 A;  2KIG A;  2B5R C;  2PXG A;  4KHB A;  4QXA B;  3TW1 A;  3OHM B;  2RRF A;  4KHO A;  4L1R A;  3A58 A;  4OT1 A;  2GCL A;  2GUM A;  4Z2N A;  2Z4D A;  3HIE A;  2Z14 A;  3C4O B;  4IOY X;  5M4Y B;  3E2L C;  3N4I B;  5I2M A;  2ZKM X;  4DM5 A;  4QJ4 B;  2GCJ A;  2K8E A;  4QJ3 B;  3C4P B;  4DIX A;  5D0Q E;  3NWF A;  2K49 A;  2NBV A;  3FSS A;  3E2K C;  4OSN A;  3TO1 A;  3GYP A;  3NWD A;  2FJU B;  5D0O E;  1XXM C;  2G2W B;  2KXX A;  1JTG B;  3D4E A;  4D6W A;  1ZYI A;  2KUQ A;  1S0W C;  4GOU A;  4PQ0 A;  4GNK B;  2R2Y A;  2KR0 A;  2G2U B;  3U12 A;  3TVV A;  5EKQ E;  4Z2M B;  3FVC A;  5LG4 B;  3NW8 A;  4QJ5 B;  4IFS A;  3GMU B;  3GYO A;  2Z59 A;  2KM7 A;  3C7V B;  3C7U B;  4KHA A;  3NWA A;  4KHB B;  4HSI A;  5AYW E;  2YH9 A;  2KIE A;  2Z13 A;  4CSQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...