3OD8A

Human parp-1 zinc finger 1 (zn1) bound to dna
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
87
structure length
87
Chain Sequence
SDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein/dna
molecule keywords Poly [ADP-ribose] polymerase 1
publication title Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
pubmed doi rcsb
source organism Homo sapiens
total genus 18
structure length 87
sequence length 87
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2010-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00645 zf-PARP Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1740.10 Alpha Beta 2-Layer Sandwich first zn-finger domain of poly(adp-ribose) polymerase-1 Zinc finger, PARP-type 3od8A00
2DMJA 3ODEA 3OD8A 2L31A 2L30A 4OPXA 2N8AA 4DQYA 2CS2A 3ODAA 4OQAA 1V9XA 3ODCA 4OQBA 4AV1A 1UW0A
chains in the Genus database with same CATH superfamily
3J80a 2L31A 3J7A3 4OPXA 4AV1A 1UW0A 3OD8A 2CS2A 3JAMa 5LL6e 2N8AA 3ODCA 4OQBA 2DMJA 3ODEA 2L30A 4DQYA 3ODAA 4OQAA 5FLXa 5A2Qa 1V9XA 5IT9a 3J81a
chains in the Genus database with same CATH topology
2DMJA 3ODEA 3OD8A 2L31A 2L30A 4OPXA 2N8AA 4DQYA 2CS2A 3ODAA 4OQAA 1V9XA 3ODCA 4OQBA 4AV1A 1UW0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DMJ A;  3ODE A;  3OD8 A;  2L31 A;  2L30 A;  4OPX A;  2N8A A;  4DQY A;  2CS2 A;  3ODA A;  4OQA A;  1V9X A;  3ODC A;  4OQB A;  4AV1 A;  1UW0 A; 
#chains in the Genus database with same CATH topology
 3J80 a;  2L31 A;  3J7A 3;  4OPX A;  4AV1 A;  1UW0 A;  3OD8 A;  2CS2 A;  3JAM a;  5LL6 e;  2N8A A;  3ODC A;  4OQB A;  2DMJ A;  3ODE A;  2L30 A;  4DQY A;  3ODA A;  4OQA A;  5FLX a;  5A2Q a;  1V9X A;  5IT9 a;  3J81 a; 
#chains in the Genus database with same CATH homology
 2DMJ A;  3ODE A;  3OD8 A;  2L31 A;  2L30 A;  4OPX A;  2N8A A;  4DQY A;  2CS2 A;  3ODA A;  4OQA A;  1V9X A;  3ODC A;  4OQB A;  4AV1 A;  1UW0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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