3PKBA

M. tuberculosis metap with bengamide analog y16, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkbA01
1XGNA 2BWXA 1QXYA 2B3LA 4FKCA 2EA4A 1CHMA 1MATA 3TAVA 2V6CA 4EGEA 3MR1A 2EA2A 1C24A 4JUQA 4FO8A 3L24A 4KM3A 4MATA 1YVMA 1XGSA 2GG2A 4U1BA 2EVMA 2Q95A 2GG3A 1WY2A 3PKDA 1WKMA 4U6ZA 3PKCA 1BOAA 1C22A 2BHCA 2GU5A 1WL9A 4FLIA 3S6BA 2EVCA 3IG4A 5CDVA 2P98A 5JI6A 4U69A 1WBQA 4ZNGA 1B59A 3IU7A 3FMRA 4FLKA 2V3ZA 3D27A 1O0XA 5CDLA 5CE6A 4PV4A 3IU8A 4ZWOA 1YW8A 2BB7A 2ZSGA 1WLRA 1R5HA 4IPAA 1KP0A 4U75A 4B28A 1W7VA 2GG8A 1C27A 2V3YA 4S2RP 3PKEA 4U73A 1R5GA 4IU6A 5CLSA 1WL6A 4ZWPA 2P9AA 3L7GA 2OKNA 2GU4A 1XNZA 2BHAA 2GA2A 4U70A 1M35A 2GGBA 4U6EA 2B3HA 4IKUA 5CIKA 5FCHA 1A16A 4RGZ1 4U6WA 2BWUA 5CDEA 5D6FA 2HOWA 2MATA 3CB5A 1JAWA 2BHBA 2GU7A 4IKSA 1R58A 2ADUA 3BIQA 4HXXA 4IECA 1YJ3A 3FM3A 1B6AA 1N51A 2BWWA 4ZWUA 2Q93A 4S2TP 2EVOA 1BN5A 4RZYA 3Q6DA 4OOKA 2G6PA 3PKBA 3FMQA 4IKTA 2GU6A 4S01A 3TB5A 4FUKA 1C21A 2NQ6A 1Y1NA 4A6WA 2NQ7A 2Q96A 5E5BA 3IU9A 1KQ0A 2BH3A 1YW9A 2DFIA 5FCFA 4IF7A 3CTZA 2GZ5A 5JHUA 1C23A 1XGOA 5JFRA 1QXWA 2IW2A 2B3KA 3MX6A 1QXZA 2Q92A 3PKAA 2GG0A 2Q94A 2BWTA 4Z7MA 2BWYA 1YW7A 4IDYA 1PV9A 4R60A 4QR8A 1QZYA 4RZZA 2Q8KA 1W2MA 3BITA 3RVAA 3MATA 4FO7A 2GG7A 5CNXA 2BHDA 1WN1A 3CB6A 1XGMA 2P99A 4U6CA 3RORA 2BWVA 2GTXA 4FLLA 2OAZA 4U6JA 4PNCA 4U71A 2BN7A 2GG5A 5D6EA 2GGCA 2BWSA 4S00A 4IKRA 2V3XA 4FLJA 1KQ9A 4U76A 3BIPA 2GG9A 4A6VA
chains in the Genus database with same CATH superfamily
1XGNA 2BWXA 1QXYA 2B3LA 4FKCA 2EA4A 1CHMA 1MATA 3TAVA 2V6CA 4EGEA 3MR1A 2EA2A 1C24A 4JUQA 4FO8A 3L24A 4KM3A 4MATA 1YVMA 1XGSA 2GG2A 4U1BA 2EVMA 2Q95A 2GG3A 1WY2A 3PKDA 1WKMA 4U6ZA 3PKCA 1BOAA 1C22A 2BHCA 2GU5A 1WL9A 4FLIA 3S6BA 2EVCA 3IG4A 5CDVA 2P98A 5JI6A 4U69A 1WBQA 4ZNGA 1B59A 3IU7A 3FMRA 4FLKA 2V3ZA 3D27A 1O0XA 5CDLA 5CE6A 4PV4A 3IU8A 4ZWOA 1YW8A 2BB7A 2ZSGA 1WLRA 1R5HA 4IPAA 1KP0A 4U75A 4B28A 1W7VA 2GG8A 1C27A 2V3YA 4S2RP 3PKEA 4U73A 1R5GA 4IU6A 5CLSA 1WL6A 4ZWPA 2P9AA 3L7GA 2OKNA 2GU4A 1XNZA 2BHAA 2GA2A 4U70A 1M35A 2GGBA 4U6EA 2B3HA 4IKUA 5CIKA 5FCHA 1A16A 4RGZ1 4U6WA 2BWUA 5CDEA 5D6FA 2HOWA 2MATA 3CB5A 1JAWA 2BHBA 2GU7A 4IKSA 1R58A 2ADUA 3BIQA 4HXXA 4IECA 1YJ3A 3FM3A 1B6AA 1N51A 2BWWA 4ZWUA 2Q93A 4S2TP 2EVOA 1BN5A 4RZYA 3Q6DA 4OOKA 2G6PA 3PKBA 3FMQA 4IKTA 2GU6A 4S01A 3TB5A 4FUKA 1C21A 2NQ6A 1Y1NA 4A6WA 2NQ7A 2Q96A 5E5BA 3IU9A 1KQ0A 2BH3A 1YW9A 2DFIA 5FCFA 4IF7A 3CTZA 2GZ5A 5JHUA 1C23A 1XGOA 5JFRA 1QXWA 2IW2A 2B3KA 3MX6A 1QXZA 2Q92A 3PKAA 2GG0A 2Q94A 2BWTA 4Z7MA 2BWYA 1YW7A 4IDYA 1PV9A 4R60A 4QR8A 1QZYA 4RZZA 2Q8KA 1W2MA 3BITA 3RVAA 3MATA 4FO7A 2GG7A 5CNXA 2BHDA 1WN1A 3CB6A 1XGMA 2P99A 4U6CA 3RORA 2BWVA 2GTXA 4FLLA 2OAZA 4U6JA 4PNCA 4U71A 2BN7A 2GG5A 5D6EA 2GGCA 2BWSA 4S00A 4IKRA 2V3XA 4FLJA 1KQ9A 4U76A 3BIPA 2GG9A 4A6VA
chains in the Genus database with same CATH topology
1XGNA 2BWXA 1QXYA 2B3LA 4FKCA 2EA4A 1CHMA 1MATA 3TAVA 2V6CA 4EGEA 3MR1A 2EA2A 1C24A 4JUQA 4FO8A 3L24A 4KM3A 4MATA 1YVMA 1XGSA 2GG2A 4U1BA 2EVMA 2Q95A 2GG3A 1WY2A 3PKDA 1WKMA 4U6ZA 3PKCA 1BOAA 1C22A 2BHCA 2GU5A 1WL9A 4FLIA 3S6BA 2EVCA 3IG4A 5CDVA 2P98A 5JI6A 4U69A 1WBQA 4ZNGA 1B59A 3IU7A 3FMRA 4FLKA 2V3ZA 3D27A 1O0XA 5CDLA 5CE6A 4PV4A 3IU8A 4ZWOA 1YW8A 2BB7A 2ZSGA 1WLRA 1R5HA 4IPAA 1KP0A 4U75A 4B28A 1W7VA 2GG8A 1C27A 2V3YA 4S2RP 3PKEA 4U73A 1R5GA 4IU6A 5CLSA 1WL6A 4ZWPA 2P9AA 3L7GA 2OKNA 2GU4A 1XNZA 2BHAA 2GA2A 4U70A 1M35A 2GGBA 4U6EA 2B3HA 4IKUA 5CIKA 5FCHA 1A16A 4RGZ1 4U6WA 2BWUA 5CDEA 5D6FA 2HOWA 2MATA 3CB5A 1JAWA 2BHBA 2GU7A 4IKSA 1R58A 2ADUA 3BIQA 4HXXA 4IECA 1YJ3A 3FM3A 1B6AA 1N51A 2BWWA 4ZWUA 2Q93A 4S2TP 2EVOA 1BN5A 4RZYA 3Q6DA 4OOKA 2G6PA 3PKBA 3FMQA 4IKTA 2GU6A 4S01A 3TB5A 4FUKA 1C21A 2NQ6A 1Y1NA 4A6WA 2NQ7A 2Q96A 5E5BA 3IU9A 1KQ0A 2BH3A 1YW9A 2DFIA 5FCFA 4IF7A 3CTZA 2GZ5A 5JHUA 1C23A 1XGOA 5JFRA 1QXWA 2IW2A 2B3KA 3MX6A 1QXZA 2Q92A 3PKAA 2GG0A 2Q94A 2BWTA 4Z7MA 2BWYA 1YW7A 4IDYA 1PV9A 4R60A 4QR8A 1QZYA 4RZZA 2Q8KA 1W2MA 3BITA 3RVAA 3MATA 4FO7A 2GG7A 5CNXA 2BHDA 1WN1A 3CB6A 1XGMA 2P99A 4U6CA 3RORA 2BWVA 2GTXA 4FLLA 2OAZA 4U6JA 4PNCA 4U71A 2BN7A 2GG5A 5D6EA 2GGCA 2BWSA 4S00A 4IKRA 2V3XA 4FLJA 1KQ9A 4U76A 3BIPA 2GG9A 4A6VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XGN A;  2BWX A;  1QXY A;  2B3L A;  4FKC A;  2EA4 A;  1CHM A;  1MAT A;  3TAV A;  2V6C A;  4EGE A;  3MR1 A;  2EA2 A;  1C24 A;  4JUQ A;  4FO8 A;  3L24 A;  4KM3 A;  4MAT A;  1YVM A;  1XGS A;  2GG2 A;  4U1B A;  2EVM A;  2Q95 A;  2GG3 A;  1WY2 A;  3PKD A;  1WKM A;  4U6Z A;  3PKC A;  1BOA A;  1C22 A;  2BHC A;  2GU5 A;  1WL9 A;  4FLI A;  3S6B A;  2EVC A;  3IG4 A;  5CDV A;  2P98 A;  5JI6 A;  4U69 A;  1WBQ A;  4ZNG A;  1B59 A;  3IU7 A;  3FMR A;  4FLK A;  2V3Z A;  3D27 A;  1O0X A;  5CDL A;  5CE6 A;  4PV4 A;  3IU8 A;  4ZWO A;  1YW8 A;  2BB7 A;  2ZSG A;  1WLR A;  1R5H A;  4IPA A;  1KP0 A;  4U75 A;  4B28 A;  1W7V A;  2GG8 A;  1C27 A;  2V3Y A;  4S2R P;  3PKE A;  4U73 A;  1R5G A;  4IU6 A;  5CLS A;  1WL6 A;  4ZWP A;  2P9A A;  3L7G A;  2OKN A;  2GU4 A;  1XNZ A;  2BHA A;  2GA2 A;  4U70 A;  1M35 A;  2GGB A;  4U6E A;  2B3H A;  4IKU A;  5CIK A;  5FCH A;  1A16 A;  4RGZ 1;  4U6W A;  2BWU A;  5CDE A;  5D6F A;  2HOW A;  2MAT A;  3CB5 A;  1JAW A;  2BHB A;  2GU7 A;  4IKS A;  1R58 A;  2ADU A;  3BIQ A;  4HXX A;  4IEC A;  1YJ3 A;  3FM3 A;  1B6A A;  1N51 A;  2BWW A;  4ZWU A;  2Q93 A;  4S2T P;  2EVO A;  1BN5 A;  4RZY A;  3Q6D A;  4OOK A;  2G6P A;  3PKB A;  3FMQ A;  4IKT A;  2GU6 A;  4S01 A;  3TB5 A;  4FUK A;  1C21 A;  2NQ6 A;  1Y1N A;  4A6W A;  2NQ7 A;  2Q96 A;  5E5B A;  3IU9 A;  1KQ0 A;  2BH3 A;  1YW9 A;  2DFI A;  5FCF A;  4IF7 A;  3CTZ A;  2GZ5 A;  5JHU A;  1C23 A;  1XGO A;  5JFR A;  1QXW A;  2IW2 A;  2B3K A;  3MX6 A;  1QXZ A;  2Q92 A;  3PKA A;  2GG0 A;  2Q94 A;  2BWT A;  4Z7M A;  2BWY A;  1YW7 A;  4IDY A;  1PV9 A;  4R60 A;  4QR8 A;  1QZY A;  4RZZ A;  2Q8K A;  1W2M A;  3BIT A;  3RVA A;  3MAT A;  4FO7 A;  2GG7 A;  5CNX A;  2BHD A;  1WN1 A;  3CB6 A;  1XGM A;  2P99 A;  4U6C A;  3ROR A;  2BWV A;  2GTX A;  4FLL A;  2OAZ A;  4U6J A;  4PNC A;  4U71 A;  2BN7 A;  2GG5 A;  5D6E A;  2GGC A;  2BWS A;  4S00 A;  4IKR A;  2V3X A;  4FLJ A;  1KQ9 A;  4U76 A;  3BIP A;  2GG9 A;  4A6V A; 
#chains in the Genus database with same CATH topology
 1XGN A;  2BWX A;  1QXY A;  2B3L A;  4FKC A;  2EA4 A;  1CHM A;  1MAT A;  3TAV A;  2V6C A;  4EGE A;  3MR1 A;  2EA2 A;  1C24 A;  4JUQ A;  4FO8 A;  3L24 A;  4KM3 A;  4MAT A;  1YVM A;  1XGS A;  2GG2 A;  4U1B A;  2EVM A;  2Q95 A;  2GG3 A;  1WY2 A;  3PKD A;  1WKM A;  4U6Z A;  3PKC A;  1BOA A;  1C22 A;  2BHC A;  2GU5 A;  1WL9 A;  4FLI A;  3S6B A;  2EVC A;  3IG4 A;  5CDV A;  2P98 A;  5JI6 A;  4U69 A;  1WBQ A;  4ZNG A;  1B59 A;  3IU7 A;  3FMR A;  4FLK A;  2V3Z A;  3D27 A;  1O0X A;  5CDL A;  5CE6 A;  4PV4 A;  3IU8 A;  4ZWO A;  1YW8 A;  2BB7 A;  2ZSG A;  1WLR A;  1R5H A;  4IPA A;  1KP0 A;  4U75 A;  4B28 A;  1W7V A;  2GG8 A;  1C27 A;  2V3Y A;  4S2R P;  3PKE A;  4U73 A;  1R5G A;  4IU6 A;  5CLS A;  1WL6 A;  4ZWP A;  2P9A A;  3L7G A;  2OKN A;  2GU4 A;  1XNZ A;  2BHA A;  2GA2 A;  4U70 A;  1M35 A;  2GGB A;  4U6E A;  2B3H A;  4IKU A;  5CIK A;  5FCH A;  1A16 A;  4RGZ 1;  4U6W A;  2BWU A;  5CDE A;  5D6F A;  2HOW A;  2MAT A;  3CB5 A;  1JAW A;  2BHB A;  2GU7 A;  4IKS A;  1R58 A;  2ADU A;  3BIQ A;  4HXX A;  4IEC A;  1YJ3 A;  3FM3 A;  1B6A A;  1N51 A;  2BWW A;  4ZWU A;  2Q93 A;  4S2T P;  2EVO A;  1BN5 A;  4RZY A;  3Q6D A;  4OOK A;  2G6P A;  3PKB A;  3FMQ A;  4IKT A;  2GU6 A;  4S01 A;  3TB5 A;  4FUK A;  1C21 A;  2NQ6 A;  1Y1N A;  4A6W A;  2NQ7 A;  2Q96 A;  5E5B A;  3IU9 A;  1KQ0 A;  2BH3 A;  1YW9 A;  2DFI A;  5FCF A;  4IF7 A;  3CTZ A;  2GZ5 A;  5JHU A;  1C23 A;  1XGO A;  5JFR A;  1QXW A;  2IW2 A;  2B3K A;  3MX6 A;  1QXZ A;  2Q92 A;  3PKA A;  2GG0 A;  2Q94 A;  2BWT A;  4Z7M A;  2BWY A;  1YW7 A;  4IDY A;  1PV9 A;  4R60 A;  4QR8 A;  1QZY A;  4RZZ A;  2Q8K A;  1W2M A;  3BIT A;  3RVA A;  3MAT A;  4FO7 A;  2GG7 A;  5CNX A;  2BHD A;  1WN1 A;  3CB6 A;  1XGM A;  2P99 A;  4U6C A;  3ROR A;  2BWV A;  2GTX A;  4FLL A;  2OAZ A;  4U6J A;  4PNC A;  4U71 A;  2BN7 A;  2GG5 A;  5D6E A;  2GGC A;  2BWS A;  4S00 A;  4IKR A;  2V3X A;  4FLJ A;  1KQ9 A;  4U76 A;  3BIP A;  2GG9 A;  4A6V A; 
#chains in the Genus database with same CATH homology
 1XGN A;  2BWX A;  1QXY A;  2B3L A;  4FKC A;  2EA4 A;  1CHM A;  1MAT A;  3TAV A;  2V6C A;  4EGE A;  3MR1 A;  2EA2 A;  1C24 A;  4JUQ A;  4FO8 A;  3L24 A;  4KM3 A;  4MAT A;  1YVM A;  1XGS A;  2GG2 A;  4U1B A;  2EVM A;  2Q95 A;  2GG3 A;  1WY2 A;  3PKD A;  1WKM A;  4U6Z A;  3PKC A;  1BOA A;  1C22 A;  2BHC A;  2GU5 A;  1WL9 A;  4FLI A;  3S6B A;  2EVC A;  3IG4 A;  5CDV A;  2P98 A;  5JI6 A;  4U69 A;  1WBQ A;  4ZNG A;  1B59 A;  3IU7 A;  3FMR A;  4FLK A;  2V3Z A;  3D27 A;  1O0X A;  5CDL A;  5CE6 A;  4PV4 A;  3IU8 A;  4ZWO A;  1YW8 A;  2BB7 A;  2ZSG A;  1WLR A;  1R5H A;  4IPA A;  1KP0 A;  4U75 A;  4B28 A;  1W7V A;  2GG8 A;  1C27 A;  2V3Y A;  4S2R P;  3PKE A;  4U73 A;  1R5G A;  4IU6 A;  5CLS A;  1WL6 A;  4ZWP A;  2P9A A;  3L7G A;  2OKN A;  2GU4 A;  1XNZ A;  2BHA A;  2GA2 A;  4U70 A;  1M35 A;  2GGB A;  4U6E A;  2B3H A;  4IKU A;  5CIK A;  5FCH A;  1A16 A;  4RGZ 1;  4U6W A;  2BWU A;  5CDE A;  5D6F A;  2HOW A;  2MAT A;  3CB5 A;  1JAW A;  2BHB A;  2GU7 A;  4IKS A;  1R58 A;  2ADU A;  3BIQ A;  4HXX A;  4IEC A;  1YJ3 A;  3FM3 A;  1B6A A;  1N51 A;  2BWW A;  4ZWU A;  2Q93 A;  4S2T P;  2EVO A;  1BN5 A;  4RZY A;  3Q6D A;  4OOK A;  2G6P A;  3PKB A;  3FMQ A;  4IKT A;  2GU6 A;  4S01 A;  3TB5 A;  4FUK A;  1C21 A;  2NQ6 A;  1Y1N A;  4A6W A;  2NQ7 A;  2Q96 A;  5E5B A;  3IU9 A;  1KQ0 A;  2BH3 A;  1YW9 A;  2DFI A;  5FCF A;  4IF7 A;  3CTZ A;  2GZ5 A;  5JHU A;  1C23 A;  1XGO A;  5JFR A;  1QXW A;  2IW2 A;  2B3K A;  3MX6 A;  1QXZ A;  2Q92 A;  3PKA A;  2GG0 A;  2Q94 A;  2BWT A;  4Z7M A;  2BWY A;  1YW7 A;  4IDY A;  1PV9 A;  4R60 A;  4QR8 A;  1QZY A;  4RZZ A;  2Q8K A;  1W2M A;  3BIT A;  3RVA A;  3MAT A;  4FO7 A;  2GG7 A;  5CNX A;  2BHD A;  1WN1 A;  3CB6 A;  1XGM A;  2P99 A;  4U6C A;  3ROR A;  2BWV A;  2GTX A;  4FLL A;  2OAZ A;  4U6J A;  4PNC A;  4U71 A;  2BN7 A;  2GG5 A;  5D6E A;  2GGC A;  2BWS A;  4S00 A;  4IKR A;  2V3X A;  4FLJ A;  1KQ9 A;  4U76 A;  3BIP A;  2GG9 A;  4A6V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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