3PKDA

M. tuberculosis metap with bengamide analog y10, in mn form
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkdA01
4PNCA 2OAZA 2B3LA 2HOWA 4U6CA 4U73A 1KP0A 1XGNA 4IDYA 4U6ZA 1WBQA 3Q6DA 2Q96A 4A6VA 3TB5A 1YW8A 4IKSA 1XNZA 2IW2A 2V6CA 2EA2A 3PKBA 4FLIA 1R5HA 3PKCA 3TAVA 1Y1NA 2GZ5A 3CTZA 2GA2A 2NQ6A 4RGZ1 4QR8A 5FCFA 4S00A 5CDLA 5CLSA 4RZZA 4IKUA 3PKEA 2GG9A 4R60A 2BWXA 4FKCA 4IU6A 1XGMA 5JHUA 1WL9A 4IF7A 2V3YA 1JAWA 2GU5A 2EA4A 2GU6A 1YJ3A 3BIQA 1WN1A 2EVMA 3L7GA 4HXXA 4S2TP 1BN5A 1C27A 4OOKA 4ZNGA 3PKAA 4ZWPA 4Z7MA 4FLKA 3IU7A 1WLRA 1MATA 2DFIA 1WKMA 5D6FA 1O0XA 3MATA 1XGOA 4EGEA 4S2RP 2Q8KA 1QXZA 1QXYA 2GG2A 2BHDA 1C22A 3PKDA 2BHBA 4FLJA 1C24A 4U6EA 2BWWA 5CDEA 4ZWOA 2GTXA 2V3ZA 1B6AA 5CDVA 2GG3A 4U6WA 5CNXA 2BN7A 2GG7A 5D6EA 5E5BA 1B59A 2BH3A 4U76A 4JUQA 2BWUA 1WY2A 2ADUA 2GG8A 2GG5A 1CHMA 2BWVA 2P99A 3CB6A 4KM3A 1W2MA 4IKTA 5CE6A 3IU9A 3BITA 2P9AA 2BWSA 2G6PA 1C23A 1BOAA 3D27A 4FO8A 1KQ9A 2BHAA 2B3HA 4U75A 4U70A 2BB7A 2BHCA 2NQ7A 3RORA 1W7VA 3MX6A 2ZSGA 1C21A 4FLLA 5FCHA 1PV9A 3IU8A 5JI6A 2Q94A 1A16A 2Q92A 1XGSA 3IG4A 2BWYA 1QXWA 3RVAA 4MATA 3S6BA 4S01A 2EVOA 1YW7A 3MR1A 2GGCA 1YVMA 1R58A 4IKRA 4IPAA 1YW9A 3BIPA 4IECA 4PV4A 2B3KA 2V3XA 5CIKA 3FMRA 4FUKA 2GU4A 4ZWUA 4U69A 1QZYA 3FM3A 4RZYA 4U1BA 2EVCA 2GU7A 3FMQA 2BWTA 4B28A 1KQ0A 1WL6A 4U71A 3CB5A 4A6WA 4FO7A 5JFRA 1N51A 2P98A 2GGBA 2GG0A 2MATA 4U6JA 2OKNA 2Q93A 1R5GA 1M35A 3L24A 2Q95A
chains in the Genus database with same CATH superfamily
4PNCA 2OAZA 2B3LA 2HOWA 4U6CA 4U73A 1KP0A 1XGNA 4IDYA 4U6ZA 1WBQA 3Q6DA 2Q96A 4A6VA 3TB5A 1YW8A 4IKSA 1XNZA 2IW2A 2V6CA 2EA2A 3PKBA 4FLIA 1R5HA 3PKCA 3TAVA 1Y1NA 2GZ5A 3CTZA 2GA2A 2NQ6A 4RGZ1 4QR8A 5FCFA 4S00A 5CDLA 5CLSA 4RZZA 4IKUA 3PKEA 2GG9A 4R60A 2BWXA 4FKCA 4IU6A 1XGMA 5JHUA 1WL9A 4IF7A 2V3YA 1JAWA 2GU5A 2EA4A 2GU6A 1YJ3A 3BIQA 1WN1A 2EVMA 3L7GA 4HXXA 4S2TP 1BN5A 1C27A 4OOKA 4ZNGA 3PKAA 4ZWPA 4Z7MA 4FLKA 3IU7A 1WLRA 1MATA 2DFIA 1WKMA 5D6FA 1O0XA 3MATA 1XGOA 4EGEA 4S2RP 2Q8KA 1QXZA 1QXYA 2GG2A 2BHDA 1C22A 3PKDA 2BHBA 4FLJA 1C24A 4U6EA 2BWWA 5CDEA 4ZWOA 2GTXA 2V3ZA 1B6AA 5CDVA 2GG3A 4U6WA 5CNXA 2BN7A 2GG7A 5D6EA 5E5BA 1B59A 2BH3A 4U76A 4JUQA 2BWUA 1WY2A 2ADUA 2GG8A 2GG5A 1CHMA 2BWVA 2P99A 3CB6A 4KM3A 1W2MA 4IKTA 5CE6A 3IU9A 3BITA 2P9AA 2BWSA 2G6PA 1C23A 1BOAA 3D27A 4FO8A 1KQ9A 2BHAA 2B3HA 4U75A 4U70A 2BB7A 2BHCA 2NQ7A 3RORA 1W7VA 3MX6A 2ZSGA 1C21A 4FLLA 5FCHA 1PV9A 3IU8A 5JI6A 2Q94A 1A16A 2Q92A 1XGSA 3IG4A 2BWYA 1QXWA 3RVAA 4MATA 3S6BA 4S01A 2EVOA 1YW7A 3MR1A 2GGCA 1YVMA 1R58A 4IKRA 4IPAA 1YW9A 3BIPA 4IECA 4PV4A 2B3KA 2V3XA 5CIKA 3FMRA 4FUKA 2GU4A 4ZWUA 4U69A 1QZYA 3FM3A 4RZYA 4U1BA 2EVCA 2GU7A 3FMQA 2BWTA 4B28A 1KQ0A 1WL6A 4U71A 3CB5A 4A6WA 4FO7A 5JFRA 1N51A 2P98A 2GGBA 2GG0A 2MATA 4U6JA 2OKNA 2Q93A 1R5GA 1M35A 3L24A 2Q95A
chains in the Genus database with same CATH topology
4PNCA 2OAZA 2B3LA 2HOWA 4U6CA 4U73A 1KP0A 1XGNA 4IDYA 4U6ZA 1WBQA 3Q6DA 2Q96A 4A6VA 3TB5A 1YW8A 4IKSA 1XNZA 2IW2A 2V6CA 2EA2A 3PKBA 4FLIA 1R5HA 3PKCA 3TAVA 1Y1NA 2GZ5A 3CTZA 2GA2A 2NQ6A 4RGZ1 4QR8A 5FCFA 4S00A 5CDLA 5CLSA 4RZZA 4IKUA 3PKEA 2GG9A 4R60A 2BWXA 4FKCA 4IU6A 1XGMA 5JHUA 1WL9A 4IF7A 2V3YA 1JAWA 2GU5A 2EA4A 2GU6A 1YJ3A 3BIQA 1WN1A 2EVMA 3L7GA 4HXXA 4S2TP 1BN5A 1C27A 4OOKA 4ZNGA 3PKAA 4ZWPA 4Z7MA 4FLKA 3IU7A 1WLRA 1MATA 2DFIA 1WKMA 5D6FA 1O0XA 3MATA 1XGOA 4EGEA 4S2RP 2Q8KA 1QXZA 1QXYA 2GG2A 2BHDA 1C22A 3PKDA 2BHBA 4FLJA 1C24A 4U6EA 2BWWA 5CDEA 4ZWOA 2GTXA 2V3ZA 1B6AA 5CDVA 2GG3A 4U6WA 5CNXA 2BN7A 2GG7A 5D6EA 5E5BA 1B59A 2BH3A 4U76A 4JUQA 2BWUA 1WY2A 2ADUA 2GG8A 2GG5A 1CHMA 2BWVA 2P99A 3CB6A 4KM3A 1W2MA 4IKTA 5CE6A 3IU9A 3BITA 2P9AA 2BWSA 2G6PA 1C23A 1BOAA 3D27A 4FO8A 1KQ9A 2BHAA 2B3HA 4U75A 4U70A 2BB7A 2BHCA 2NQ7A 3RORA 1W7VA 3MX6A 2ZSGA 1C21A 4FLLA 5FCHA 1PV9A 3IU8A 5JI6A 2Q94A 1A16A 2Q92A 1XGSA 3IG4A 2BWYA 1QXWA 3RVAA 4MATA 3S6BA 4S01A 2EVOA 1YW7A 3MR1A 2GGCA 1YVMA 1R58A 4IKRA 4IPAA 1YW9A 3BIPA 4IECA 4PV4A 2B3KA 2V3XA 5CIKA 3FMRA 4FUKA 2GU4A 4ZWUA 4U69A 1QZYA 3FM3A 4RZYA 4U1BA 2EVCA 2GU7A 3FMQA 2BWTA 4B28A 1KQ0A 1WL6A 4U71A 3CB5A 4A6WA 4FO7A 5JFRA 1N51A 2P98A 2GGBA 2GG0A 2MATA 4U6JA 2OKNA 2Q93A 1R5GA 1M35A 3L24A 2Q95A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PNC A;  2OAZ A;  2B3L A;  2HOW A;  4U6C A;  4U73 A;  1KP0 A;  1XGN A;  4IDY A;  4U6Z A;  1WBQ A;  3Q6D A;  2Q96 A;  4A6V A;  3TB5 A;  1YW8 A;  4IKS A;  1XNZ A;  2IW2 A;  2V6C A;  2EA2 A;  3PKB A;  4FLI A;  1R5H A;  3PKC A;  3TAV A;  1Y1N A;  2GZ5 A;  3CTZ A;  2GA2 A;  2NQ6 A;  4RGZ 1;  4QR8 A;  5FCF A;  4S00 A;  5CDL A;  5CLS A;  4RZZ A;  4IKU A;  3PKE A;  2GG9 A;  4R60 A;  2BWX A;  4FKC A;  4IU6 A;  1XGM A;  5JHU A;  1WL9 A;  4IF7 A;  2V3Y A;  1JAW A;  2GU5 A;  2EA4 A;  2GU6 A;  1YJ3 A;  3BIQ A;  1WN1 A;  2EVM A;  3L7G A;  4HXX A;  4S2T P;  1BN5 A;  1C27 A;  4OOK A;  4ZNG A;  3PKA A;  4ZWP A;  4Z7M A;  4FLK A;  3IU7 A;  1WLR A;  1MAT A;  2DFI A;  1WKM A;  5D6F A;  1O0X A;  3MAT A;  1XGO A;  4EGE A;  4S2R P;  2Q8K A;  1QXZ A;  1QXY A;  2GG2 A;  2BHD A;  1C22 A;  3PKD A;  2BHB A;  4FLJ A;  1C24 A;  4U6E A;  2BWW A;  5CDE A;  4ZWO A;  2GTX A;  2V3Z A;  1B6A A;  5CDV A;  2GG3 A;  4U6W A;  5CNX A;  2BN7 A;  2GG7 A;  5D6E A;  5E5B A;  1B59 A;  2BH3 A;  4U76 A;  4JUQ A;  2BWU A;  1WY2 A;  2ADU A;  2GG8 A;  2GG5 A;  1CHM A;  2BWV A;  2P99 A;  3CB6 A;  4KM3 A;  1W2M A;  4IKT A;  5CE6 A;  3IU9 A;  3BIT A;  2P9A A;  2BWS A;  2G6P A;  1C23 A;  1BOA A;  3D27 A;  4FO8 A;  1KQ9 A;  2BHA A;  2B3H A;  4U75 A;  4U70 A;  2BB7 A;  2BHC A;  2NQ7 A;  3ROR A;  1W7V A;  3MX6 A;  2ZSG A;  1C21 A;  4FLL A;  5FCH A;  1PV9 A;  3IU8 A;  5JI6 A;  2Q94 A;  1A16 A;  2Q92 A;  1XGS A;  3IG4 A;  2BWY A;  1QXW A;  3RVA A;  4MAT A;  3S6B A;  4S01 A;  2EVO A;  1YW7 A;  3MR1 A;  2GGC A;  1YVM A;  1R58 A;  4IKR A;  4IPA A;  1YW9 A;  3BIP A;  4IEC A;  4PV4 A;  2B3K A;  2V3X A;  5CIK A;  3FMR A;  4FUK A;  2GU4 A;  4ZWU A;  4U69 A;  1QZY A;  3FM3 A;  4RZY A;  4U1B A;  2EVC A;  2GU7 A;  3FMQ A;  2BWT A;  4B28 A;  1KQ0 A;  1WL6 A;  4U71 A;  3CB5 A;  4A6W A;  4FO7 A;  5JFR A;  1N51 A;  2P98 A;  2GGB A;  2GG0 A;  2MAT A;  4U6J A;  2OKN A;  2Q93 A;  1R5G A;  1M35 A;  3L24 A;  2Q95 A; 
#chains in the Genus database with same CATH topology
 4PNC A;  2OAZ A;  2B3L A;  2HOW A;  4U6C A;  4U73 A;  1KP0 A;  1XGN A;  4IDY A;  4U6Z A;  1WBQ A;  3Q6D A;  2Q96 A;  4A6V A;  3TB5 A;  1YW8 A;  4IKS A;  1XNZ A;  2IW2 A;  2V6C A;  2EA2 A;  3PKB A;  4FLI A;  1R5H A;  3PKC A;  3TAV A;  1Y1N A;  2GZ5 A;  3CTZ A;  2GA2 A;  2NQ6 A;  4RGZ 1;  4QR8 A;  5FCF A;  4S00 A;  5CDL A;  5CLS A;  4RZZ A;  4IKU A;  3PKE A;  2GG9 A;  4R60 A;  2BWX A;  4FKC A;  4IU6 A;  1XGM A;  5JHU A;  1WL9 A;  4IF7 A;  2V3Y A;  1JAW A;  2GU5 A;  2EA4 A;  2GU6 A;  1YJ3 A;  3BIQ A;  1WN1 A;  2EVM A;  3L7G A;  4HXX A;  4S2T P;  1BN5 A;  1C27 A;  4OOK A;  4ZNG A;  3PKA A;  4ZWP A;  4Z7M A;  4FLK A;  3IU7 A;  1WLR A;  1MAT A;  2DFI A;  1WKM A;  5D6F A;  1O0X A;  3MAT A;  1XGO A;  4EGE A;  4S2R P;  2Q8K A;  1QXZ A;  1QXY A;  2GG2 A;  2BHD A;  1C22 A;  3PKD A;  2BHB A;  4FLJ A;  1C24 A;  4U6E A;  2BWW A;  5CDE A;  4ZWO A;  2GTX A;  2V3Z A;  1B6A A;  5CDV A;  2GG3 A;  4U6W A;  5CNX A;  2BN7 A;  2GG7 A;  5D6E A;  5E5B A;  1B59 A;  2BH3 A;  4U76 A;  4JUQ A;  2BWU A;  1WY2 A;  2ADU A;  2GG8 A;  2GG5 A;  1CHM A;  2BWV A;  2P99 A;  3CB6 A;  4KM3 A;  1W2M A;  4IKT A;  5CE6 A;  3IU9 A;  3BIT A;  2P9A A;  2BWS A;  2G6P A;  1C23 A;  1BOA A;  3D27 A;  4FO8 A;  1KQ9 A;  2BHA A;  2B3H A;  4U75 A;  4U70 A;  2BB7 A;  2BHC A;  2NQ7 A;  3ROR A;  1W7V A;  3MX6 A;  2ZSG A;  1C21 A;  4FLL A;  5FCH A;  1PV9 A;  3IU8 A;  5JI6 A;  2Q94 A;  1A16 A;  2Q92 A;  1XGS A;  3IG4 A;  2BWY A;  1QXW A;  3RVA A;  4MAT A;  3S6B A;  4S01 A;  2EVO A;  1YW7 A;  3MR1 A;  2GGC A;  1YVM A;  1R58 A;  4IKR A;  4IPA A;  1YW9 A;  3BIP A;  4IEC A;  4PV4 A;  2B3K A;  2V3X A;  5CIK A;  3FMR A;  4FUK A;  2GU4 A;  4ZWU A;  4U69 A;  1QZY A;  3FM3 A;  4RZY A;  4U1B A;  2EVC A;  2GU7 A;  3FMQ A;  2BWT A;  4B28 A;  1KQ0 A;  1WL6 A;  4U71 A;  3CB5 A;  4A6W A;  4FO7 A;  5JFR A;  1N51 A;  2P98 A;  2GGB A;  2GG0 A;  2MAT A;  4U6J A;  2OKN A;  2Q93 A;  1R5G A;  1M35 A;  3L24 A;  2Q95 A; 
#chains in the Genus database with same CATH homology
 4PNC A;  2OAZ A;  2B3L A;  2HOW A;  4U6C A;  4U73 A;  1KP0 A;  1XGN A;  4IDY A;  4U6Z A;  1WBQ A;  3Q6D A;  2Q96 A;  4A6V A;  3TB5 A;  1YW8 A;  4IKS A;  1XNZ A;  2IW2 A;  2V6C A;  2EA2 A;  3PKB A;  4FLI A;  1R5H A;  3PKC A;  3TAV A;  1Y1N A;  2GZ5 A;  3CTZ A;  2GA2 A;  2NQ6 A;  4RGZ 1;  4QR8 A;  5FCF A;  4S00 A;  5CDL A;  5CLS A;  4RZZ A;  4IKU A;  3PKE A;  2GG9 A;  4R60 A;  2BWX A;  4FKC A;  4IU6 A;  1XGM A;  5JHU A;  1WL9 A;  4IF7 A;  2V3Y A;  1JAW A;  2GU5 A;  2EA4 A;  2GU6 A;  1YJ3 A;  3BIQ A;  1WN1 A;  2EVM A;  3L7G A;  4HXX A;  4S2T P;  1BN5 A;  1C27 A;  4OOK A;  4ZNG A;  3PKA A;  4ZWP A;  4Z7M A;  4FLK A;  3IU7 A;  1WLR A;  1MAT A;  2DFI A;  1WKM A;  5D6F A;  1O0X A;  3MAT A;  1XGO A;  4EGE A;  4S2R P;  2Q8K A;  1QXZ A;  1QXY A;  2GG2 A;  2BHD A;  1C22 A;  3PKD A;  2BHB A;  4FLJ A;  1C24 A;  4U6E A;  2BWW A;  5CDE A;  4ZWO A;  2GTX A;  2V3Z A;  1B6A A;  5CDV A;  2GG3 A;  4U6W A;  5CNX A;  2BN7 A;  2GG7 A;  5D6E A;  5E5B A;  1B59 A;  2BH3 A;  4U76 A;  4JUQ A;  2BWU A;  1WY2 A;  2ADU A;  2GG8 A;  2GG5 A;  1CHM A;  2BWV A;  2P99 A;  3CB6 A;  4KM3 A;  1W2M A;  4IKT A;  5CE6 A;  3IU9 A;  3BIT A;  2P9A A;  2BWS A;  2G6P A;  1C23 A;  1BOA A;  3D27 A;  4FO8 A;  1KQ9 A;  2BHA A;  2B3H A;  4U75 A;  4U70 A;  2BB7 A;  2BHC A;  2NQ7 A;  3ROR A;  1W7V A;  3MX6 A;  2ZSG A;  1C21 A;  4FLL A;  5FCH A;  1PV9 A;  3IU8 A;  5JI6 A;  2Q94 A;  1A16 A;  2Q92 A;  1XGS A;  3IG4 A;  2BWY A;  1QXW A;  3RVA A;  4MAT A;  3S6B A;  4S01 A;  2EVO A;  1YW7 A;  3MR1 A;  2GGC A;  1YVM A;  1R58 A;  4IKR A;  4IPA A;  1YW9 A;  3BIP A;  4IEC A;  4PV4 A;  2B3K A;  2V3X A;  5CIK A;  3FMR A;  4FUK A;  2GU4 A;  4ZWU A;  4U69 A;  1QZY A;  3FM3 A;  4RZY A;  4U1B A;  2EVC A;  2GU7 A;  3FMQ A;  2BWT A;  4B28 A;  1KQ0 A;  1WL6 A;  4U71 A;  3CB5 A;  4A6W A;  4FO7 A;  5JFR A;  1N51 A;  2P98 A;  2GGB A;  2GG0 A;  2MAT A;  4U6J A;  2OKN A;  2Q93 A;  1R5G A;  1M35 A;  3L24 A;  2Q95 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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