3RL3A

Rat metallophosphodiesterase mpped2
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
276
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Metallophosphoesterase MPPED2
publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 86
structure length 276
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl3A00
1OI8A 3K7VC 4FCXA 4FBWA 1W24A 2O8AA 4UT3B 5B8IA 4M0VA 4IYPC 3PSNA 4MOYA 4O24A 2YVTA 4LACC 4UT2A 4OR9A 3CK2A 3K7WC 2O8GA 1S8EA 3QFMA 4V0WA 3EGHA 2GJUA 5INBA 1QHWA 3QFKA 4WWLA 2P6BA 3H66A 1XZWA 4H2BA 3IB8A 3H60A 4Q7FA 3DSCA 3H62B 4ORAA 2IE4C 2XMOA 1S70A 1U32A 4O43A 3THOB 3H64A 2QJCA 4KBPA 4DHLA 2HY1A 4HD0A 4LU9A 3DSDA 3E7BA 3P71C 3H67A 4DT2A 2NXFA 3FGAC 1G5BA 2AHDA 1Z2XA 1S95A 1OIDA 2CV9A 1WARA 3AV0A 3GVEA 3IVDA 4TUGA 3RQZA 3C9FA 4H2GA 4JA9A 5EQVA 2Z72A 3RL4A 4TUIA 3PSOA 1M63A 1UF3A 3H69A 1OIEA 1S3LA 2A22A 3ICFA 2IAEC 3ZU0A 1HP1A 2NYMC 4V0XA 5DNYA 2NPPC 1AUIA 2QFPA 1HPUA 1QFCA 4IL1A 4ZX2A 2DFJA 3RL3A 3H63A 5JPFA 2USHA 3E7AA 1SU1A 5IOHA 1T70A 4I5NC 4J6OA 1V73A 3QFOA 1JK7A 4O4KA 2Z06A 1WAO1 3N5UA 3ZTVA 1NNWA 1S3NA 4H1SA 3RL5A 2R17A 1II7A 2WDEA 2Z1AA 3IB7A 1MF8A 3QFNA 4XPNA 4MOVA 3T1IA 3THNA 5JJTA 3DW8C 2KKNA 4ZVZA 4H2IA 5GTUA 2QFRA 4O5GA 2BQ8X 4KKZA 2HYOA 2IE3C 2JOGA 4NZVA 3KBPA 1KBPA 1T71A 4H1YP 1UTEA 4V0VA 4FBQA 5J28A 4FBKA 4LTYA 2BCDA 3LL8A 3C5WC 3H61A 3V4YA 3HVQA 4UWQA 3EGGA 3AUZA 1HO5A 3JYFA 5C1VA 5F3WA 2ZBMA 2NYLC 4UT3A 1IT6A 2WDCA 1TCOA 5JPEA 5HPEA 1USHA 3H68A 4F0ZA 2WDDA 2BDXA 3IVEA 1XM7A 4ORCA 3TGHA 1FJMA 2HYPA 4JA7A 2Q8UA 4ORBA 1Z2WA 4I5LC 3QG5C 4DSYA 4B2OA 4YKEA 4G9JA 1S3MA 2WDFA 4H2FA 4MP0A
chains in the Genus database with same CATH superfamily
1OI8A 3K7VC 4FCXA 4FBWA 1W24A 2O8AA 4UT3B 5B8IA 4M0VA 4IYPC 3PSNA 4MOYA 4O24A 2YVTA 4LACC 4UT2A 4OR9A 3CK2A 3K7WC 2O8GA 1S8EA 3QFMA 4V0WA 3EGHA 2GJUA 2YEQA 5INBA 1QHWA 3QFKA 4WWLA 2P6BA 3H66A 3FLOA 1XZWA 4H2BA 3IB8A 3H60A 2ZOAA 4Q7FA 3DSCA 3H62B 4ORAA 2IE4C 2XMOA 1S70A 1U32A 4O43A 3THOB 3H64A 2QJCA 4KBPA 4DHLA 2HY1A 4HD0A 4LU9A 3DSDA 3E7BA 3P71C 3H67A 4DT2A 2NXFA 3FGAC 1G5BA 2AHDA 1Z2XA 1S95A 1OIDA 2CV9A 1WARA 3AV0A 3GVEA 3IVDA 4TUGA 3RQZA 3C9FA 4H2GA 4JA9A 5EQVA 2Z72A 3RL4A 4TUIA 3PSOA 1M63A 1UF3A 3H69A 1OIEA 1S3LA 2A22A 3ICFA 2IAEC 3ZU0A 1HP1A 2NYMC 4V0XA 5DNYA 2NPPC 1AUIA 2QFPA 1HPUA 1QFCA 4IL1A 4ZX2A 2DFJA 3RL3A 3H63A 5JPFA 2USHA 3E0JA 3E7AA 1SU1A 5IOHA 1T70A 4I5NC 4J6OA 1V73A 3QFOA 1JK7A 4O4KA 2Z06A 1WAO1 3N5UA 3ZTVA 1NNWA 1S3NA 4H1SA 3RL5A 2R17A 1II7A 2WDEA 2Z1AA 3IB7A 1MF8A 3QFNA 4XPNA 4MOVA 3T1IA 3THNA 5JJTA 3DW8C 2KKNA 4ZVZA 4H2IA 5GTUA 2QFRA 4O5GA 2BQ8X 4KKZA 2ZO9B 2HYOA 2IE3C 2JOGA 4NZVA 3KBPA 1KBPA 1T71A 4H1YP 1UTEA 4V0VA 4FBQA 5J28A 4FBKA 4LTYA 2BCDA 2DXNA 3LL8A 3C5WC 3H61A 3V4YA 3HVQA 4UWQA 3EGGA 3AUZA 1HO5A 3JYFA 5C1VA 5F3WA 2ZBMA 2NYLC 4UT3A 1IT6A 2WDCA 2DXLA 1TCOA 5JPEA 5HPEA 1USHA 3H68A 4F0ZA 2WDDA 2BDXA 3IVEA 1XM7A 4ORCA 3TGHA 1FJMA 2HYPA 4JA7A 2Q8UA 4ORBA 1Z2WA 4I5LC 3QG5C 4DSYA 4B2OA 4YKEA 4G9JA 1S3MA 3D03A 2WDFA 4H2FA 4MP0A
chains in the Genus database with same CATH topology
1OI8A 3K7VC 4FCXA 4FBWA 1W24A 2O8AA 4UT3B 5B8IA 4M0VA 4IYPC 3PSNA 4MOYA 4O24A 2YVTA 4LACC 4UT2A 4OR9A 3CK2A 3K7WC 2O8GA 1S8EA 3QFMA 4V0WA 3EGHA 2GJUA 2YEQA 5INBA 1QHWA 3QFKA 4WWLA 2P6BA 3H66A 3FLOA 1XZWA 4H2BA 3IB8A 3H60A 2ZOAA 4Q7FA 3DSCA 3H62B 4ORAA 2IE4C 2XMOA 1S70A 1U32A 4O43A 3THOB 3H64A 2QJCA 4KBPA 4DHLA 2HY1A 4HD0A 4LU9A 3DSDA 3E7BA 3P71C 3H67A 4DT2A 2NXFA 3FGAC 1G5BA 2AHDA 1Z2XA 1S95A 1OIDA 2CV9A 1WARA 3AV0A 3GVEA 3IVDA 4TUGA 3RQZA 3C9FA 4H2GA 4JA9A 5EQVA 2Z72A 3RL4A 4TUIA 3PSOA 1M63A 1UF3A 3H69A 1OIEA 1S3LA 2A22A 3ICFA 2IAEC 3ZU0A 1HP1A 2NYMC 4V0XA 5DNYA 2NPPC 1AUIA 2QFPA 1HPUA 1QFCA 4IL1A 4ZX2A 2DFJA 3RL3A 3H63A 5JPFA 2USHA 3E0JA 3E7AA 1SU1A 5IOHA 1T70A 4I5NC 4J6OA 1V73A 3QFOA 1JK7A 4O4KA 2Z06A 1WAO1 3N5UA 3ZTVA 1NNWA 1S3NA 4H1SA 3RL5A 2R17A 1II7A 2WDEA 2Z1AA 3IB7A 1MF8A 3QFNA 4XPNA 4MOVA 3T1IA 3THNA 5JJTA 3DW8C 2KKNA 4ZVZA 4H2IA 5GTUA 2QFRA 4O5GA 2BQ8X 4KKZA 2ZO9B 2HYOA 2IE3C 2JOGA 4NZVA 3KBPA 1KBPA 1T71A 4H1YP 1UTEA 4V0VA 4FBQA 5J28A 4FBKA 4LTYA 2BCDA 2DXNA 3LL8A 3C5WC 3H61A 3V4YA 3HVQA 4UWQA 3EGGA 3AUZA 1HO5A 3JYFA 5C1VA 5F3WA 2ZBMA 2NYLC 4UT3A 1IT6A 2WDCA 2DXLA 1TCOA 5JPEA 5HPEA 1USHA 3H68A 4F0ZA 2WDDA 2BDXA 3IVEA 1XM7A 4ORCA 3TGHA 1FJMA 2HYPA 4JA7A 2Q8UA 4ORBA 1Z2WA 4I5LC 3QG5C 4DSYA 4B2OA 4YKEA 4G9JA 1S3MA 3D03A 2WDFA 4H2FA 4MP0A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1OI8 A;  3K7V C;  4FCX A;  4FBW A;  1W24 A;  2O8A A;  4UT3 B;  5B8I A;  4M0V A;  4IYP C;  3PSN A;  4MOY A;  4O24 A;  2YVT A;  4LAC C;  4UT2 A;  4OR9 A;  3CK2 A;  3K7W C;  2O8G A;  1S8E A;  3QFM A;  4V0W A;  3EGH A;  2GJU A;  5INB A;  1QHW A;  3QFK A;  4WWL A;  2P6B A;  3H66 A;  1XZW A;  4H2B A;  3IB8 A;  3H60 A;  4Q7F A;  3DSC A;  3H62 B;  4ORA A;  2IE4 C;  2XMO A;  1S70 A;  1U32 A;  4O43 A;  3THO B;  3H64 A;  2QJC A;  4KBP A;  4DHL A;  2HY1 A;  4HD0 A;  4LU9 A;  3DSD A;  3E7B A;  3P71 C;  3H67 A;  4DT2 A;  2NXF A;  3FGA C;  1G5B A;  2AHD A;  1Z2X A;  1S95 A;  1OID A;  2CV9 A;  1WAR A;  3AV0 A;  3GVE A;  3IVD A;  4TUG A;  3RQZ A;  3C9F A;  4H2G A;  4JA9 A;  5EQV A;  2Z72 A;  3RL4 A;  4TUI A;  3PSO A;  1M63 A;  1UF3 A;  3H69 A;  1OIE A;  1S3L A;  2A22 A;  3ICF A;  2IAE C;  3ZU0 A;  1HP1 A;  2NYM C;  4V0X A;  5DNY A;  2NPP C;  1AUI A;  2QFP A;  1HPU A;  1QFC A;  4IL1 A;  4ZX2 A;  2DFJ A;  3RL3 A;  3H63 A;  5JPF A;  2USH A;  3E7A A;  1SU1 A;  5IOH A;  1T70 A;  4I5N C;  4J6O A;  1V73 A;  3QFO A;  1JK7 A;  4O4K A;  2Z06 A;  1WAO 1;  3N5U A;  3ZTV A;  1NNW A;  1S3N A;  4H1S A;  3RL5 A;  2R17 A;  1II7 A;  2WDE A;  2Z1A A;  3IB7 A;  1MF8 A;  3QFN A;  4XPN A;  4MOV A;  3T1I A;  3THN A;  5JJT A;  3DW8 C;  2KKN A;  4ZVZ A;  4H2I A;  5GTU A;  2QFR A;  4O5G A;  2BQ8 X;  4KKZ A;  2HYO A;  2IE3 C;  2JOG A;  4NZV A;  3KBP A;  1KBP A;  1T71 A;  4H1Y P;  1UTE A;  4V0V A;  4FBQ A;  5J28 A;  4FBK A;  4LTY A;  2BCD A;  3LL8 A;  3C5W C;  3H61 A;  3V4Y A;  3HVQ A;  4UWQ A;  3EGG A;  3AUZ A;  1HO5 A;  3JYF A;  5C1V A;  5F3W A;  2ZBM A;  2NYL C;  4UT3 A;  1IT6 A;  2WDC A;  1TCO A;  5JPE A;  5HPE A;  1USH A;  3H68 A;  4F0Z A;  2WDD A;  2BDX A;  3IVE A;  1XM7 A;  4ORC A;  3TGH A;  1FJM A;  2HYP A;  4JA7 A;  2Q8U A;  4ORB A;  1Z2W A;  4I5L C;  3QG5 C;  4DSY A;  4B2O A;  4YKE A;  4G9J A;  1S3M A;  2WDF A;  4H2F A;  4MP0 A; 
#chains in the Genus database with same CATH topology
 1OI8 A;  3K7V C;  4FCX A;  4FBW A;  1W24 A;  2O8A A;  4UT3 B;  5B8I A;  4M0V A;  4IYP C;  3PSN A;  4MOY A;  4O24 A;  2YVT A;  4LAC C;  4UT2 A;  4OR9 A;  3CK2 A;  3K7W C;  2O8G A;  1S8E A;  3QFM A;  4V0W A;  3EGH A;  2GJU A;  2YEQ A;  5INB A;  1QHW A;  3QFK A;  4WWL A;  2P6B A;  3H66 A;  3FLO A;  1XZW A;  4H2B A;  3IB8 A;  3H60 A;  2ZOA A;  4Q7F A;  3DSC A;  3H62 B;  4ORA A;  2IE4 C;  2XMO A;  1S70 A;  1U32 A;  4O43 A;  3THO B;  3H64 A;  2QJC A;  4KBP A;  4DHL A;  2HY1 A;  4HD0 A;  4LU9 A;  3DSD A;  3E7B A;  3P71 C;  3H67 A;  4DT2 A;  2NXF A;  3FGA C;  1G5B A;  2AHD A;  1Z2X A;  1S95 A;  1OID A;  2CV9 A;  1WAR A;  3AV0 A;  3GVE A;  3IVD A;  4TUG A;  3RQZ A;  3C9F A;  4H2G A;  4JA9 A;  5EQV A;  2Z72 A;  3RL4 A;  4TUI A;  3PSO A;  1M63 A;  1UF3 A;  3H69 A;  1OIE A;  1S3L A;  2A22 A;  3ICF A;  2IAE C;  3ZU0 A;  1HP1 A;  2NYM C;  4V0X A;  5DNY A;  2NPP C;  1AUI A;  2QFP A;  1HPU A;  1QFC A;  4IL1 A;  4ZX2 A;  2DFJ A;  3RL3 A;  3H63 A;  5JPF A;  2USH A;  3E0J A;  3E7A A;  1SU1 A;  5IOH A;  1T70 A;  4I5N C;  4J6O A;  1V73 A;  3QFO A;  1JK7 A;  4O4K A;  2Z06 A;  1WAO 1;  3N5U A;  3ZTV A;  1NNW A;  1S3N A;  4H1S A;  3RL5 A;  2R17 A;  1II7 A;  2WDE A;  2Z1A A;  3IB7 A;  1MF8 A;  3QFN A;  4XPN A;  4MOV A;  3T1I A;  3THN A;  5JJT A;  3DW8 C;  2KKN A;  4ZVZ A;  4H2I A;  5GTU A;  2QFR A;  4O5G A;  2BQ8 X;  4KKZ A;  2ZO9 B;  2HYO A;  2IE3 C;  2JOG A;  4NZV A;  3KBP A;  1KBP A;  1T71 A;  4H1Y P;  1UTE A;  4V0V A;  4FBQ A;  5J28 A;  4FBK A;  4LTY A;  2BCD A;  2DXN A;  3LL8 A;  3C5W C;  3H61 A;  3V4Y A;  3HVQ A;  4UWQ A;  3EGG A;  3AUZ A;  1HO5 A;  3JYF A;  5C1V A;  5F3W A;  2ZBM A;  2NYL C;  4UT3 A;  1IT6 A;  2WDC A;  2DXL A;  1TCO A;  5JPE A;  5HPE A;  1USH A;  3H68 A;  4F0Z A;  2WDD A;  2BDX A;  3IVE A;  1XM7 A;  4ORC A;  3TGH A;  1FJM A;  2HYP A;  4JA7 A;  2Q8U A;  4ORB A;  1Z2W A;  4I5L C;  3QG5 C;  4DSY A;  4B2O A;  4YKE A;  4G9J A;  1S3M A;  3D03 A;  2WDF A;  4H2F A;  4MP0 A; 
#chains in the Genus database with same CATH homology
 1OI8 A;  3K7V C;  4FCX A;  4FBW A;  1W24 A;  2O8A A;  4UT3 B;  5B8I A;  4M0V A;  4IYP C;  3PSN A;  4MOY A;  4O24 A;  2YVT A;  4LAC C;  4UT2 A;  4OR9 A;  3CK2 A;  3K7W C;  2O8G A;  1S8E A;  3QFM A;  4V0W A;  3EGH A;  2GJU A;  2YEQ A;  5INB A;  1QHW A;  3QFK A;  4WWL A;  2P6B A;  3H66 A;  3FLO A;  1XZW A;  4H2B A;  3IB8 A;  3H60 A;  2ZOA A;  4Q7F A;  3DSC A;  3H62 B;  4ORA A;  2IE4 C;  2XMO A;  1S70 A;  1U32 A;  4O43 A;  3THO B;  3H64 A;  2QJC A;  4KBP A;  4DHL A;  2HY1 A;  4HD0 A;  4LU9 A;  3DSD A;  3E7B A;  3P71 C;  3H67 A;  4DT2 A;  2NXF A;  3FGA C;  1G5B A;  2AHD A;  1Z2X A;  1S95 A;  1OID A;  2CV9 A;  1WAR A;  3AV0 A;  3GVE A;  3IVD A;  4TUG A;  3RQZ A;  3C9F A;  4H2G A;  4JA9 A;  5EQV A;  2Z72 A;  3RL4 A;  4TUI A;  3PSO A;  1M63 A;  1UF3 A;  3H69 A;  1OIE A;  1S3L A;  2A22 A;  3ICF A;  2IAE C;  3ZU0 A;  1HP1 A;  2NYM C;  4V0X A;  5DNY A;  2NPP C;  1AUI A;  2QFP A;  1HPU A;  1QFC A;  4IL1 A;  4ZX2 A;  2DFJ A;  3RL3 A;  3H63 A;  5JPF A;  2USH A;  3E0J A;  3E7A A;  1SU1 A;  5IOH A;  1T70 A;  4I5N C;  4J6O A;  1V73 A;  3QFO A;  1JK7 A;  4O4K A;  2Z06 A;  1WAO 1;  3N5U A;  3ZTV A;  1NNW A;  1S3N A;  4H1S A;  3RL5 A;  2R17 A;  1II7 A;  2WDE A;  2Z1A A;  3IB7 A;  1MF8 A;  3QFN A;  4XPN A;  4MOV A;  3T1I A;  3THN A;  5JJT A;  3DW8 C;  2KKN A;  4ZVZ A;  4H2I A;  5GTU A;  2QFR A;  4O5G A;  2BQ8 X;  4KKZ A;  2ZO9 B;  2HYO A;  2IE3 C;  2JOG A;  4NZV A;  3KBP A;  1KBP A;  1T71 A;  4H1Y P;  1UTE A;  4V0V A;  4FBQ A;  5J28 A;  4FBK A;  4LTY A;  2BCD A;  2DXN A;  3LL8 A;  3C5W C;  3H61 A;  3V4Y A;  3HVQ A;  4UWQ A;  3EGG A;  3AUZ A;  1HO5 A;  3JYF A;  5C1V A;  5F3W A;  2ZBM A;  2NYL C;  4UT3 A;  1IT6 A;  2WDC A;  2DXL A;  1TCO A;  5JPE A;  5HPE A;  1USH A;  3H68 A;  4F0Z A;  2WDD A;  2BDX A;  3IVE A;  1XM7 A;  4ORC A;  3TGH A;  1FJM A;  2HYP A;  4JA7 A;  2Q8U A;  4ORB A;  1Z2W A;  4I5L C;  3QG5 C;  4DSY A;  4B2O A;  4YKE A;  4G9J A;  1S3M A;  3D03 A;  2WDF A;  4H2F A;  4MP0 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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