3RL4A

Rat metallophosphodiesterase mpped2 g252h mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
275
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGHIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Metallophosphoesterase MPPED2
publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 91
structure length 275
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl4A00
4ORAA 5F3WA 2O8GA 2NXFA 1S95A 4V0VA 5GTUA 4H2IA 3V4YA 2NYMC 1T70A 4O24A 3H60A 3H66A 1S70A 3H63A 2QFRA 2JOGA 2WDEA 3AV0A 4DSYA 3RL4A 2A22A 1XZWA 3QFNA 3EGGA 1USHA 2Q8UA 1HP1A 1HPUA 1FJMA 1JK7A 3HVQA 1WAO1 2GJUA 2HY1A 4JA9A 2WDFA 5INBA 3E7AA 2Z1AA 3P71C 3T1IA 2DFJA 4HD0A 2XMOA 4ORBA 1S3MA 2BCDA 3DW8C 1QFCA 3RL3A 2Z06A 3EGHA 4FBQA 4LACC 3K7VC 4H2FA 1QHWA 2BDXA 3N5UA 4ORCA 3THOB 5IOHA 4NZVA 4UT3B 4YKEA 4V0XA 1S3NA 3DSDA 1II7A 4IL1A 4DHLA 4FCXA 1SU1A 1T71A 3IVDA 4I5LC 4DT2A 1S8EA 3K7WC 4FBWA 2O8AA 5EQVA 4B2OA 1S3LA 1Z2WA 4TUGA 4G9JA 1KBPA 2NYLC 3PSNA 3ZTVA 4M0VA 3H69A 2HYPA 1AUIA 3GVEA 3JYFA 4UWQA 4MOVA 4ZX2A 1WARA 1UTEA 3KBPA 3CK2A 4Q7FA 3PSOA 4LU9A 3E7BA 2QJCA 1G5BA 3H67A 3RL5A 2AHDA 3RQZA 3TGHA 1MF8A 1HO5A 4V0WA 1XM7A 4LTYA 5JPEA 1UF3A 3H64A 3QFOA 5JJTA 2WDDA 4H2BA 1NNWA 4O5GA 3H62B 3H68A 1TCOA 3H61A 3LL8A 4KBPA 4UT2A 4O4KA 4FBKA 4KKZA 3QFMA 1Z2XA 2YVTA 2QFPA 2CV9A 3C9FA 4H1YP 2IE3C 2NPPC 1IT6A 4O43A 4H1SA 1OI8A 1M63A 2R17A 1V73A 1W24A 2WDCA 3C5WC 2IE4C 4JA7A 5B8IA 1OIDA 4MP0A 5JPFA 3ZU0A 4UT3A 2BQ8X 4OR9A 4XPNA 5C1VA 4WWLA 5HPEA 5J28A 4ZVZA 4H2GA 4J6OA 4I5NC 3DSCA 2KKNA 3AUZA 5DNYA 2P6BA 2USHA 4F0ZA 2Z72A 3IB8A 4MOYA 2IAEC 1OIEA 2ZBMA 2HYOA 1U32A 3QFKA 4TUIA 3IB7A 3ICFA 3QG5C 3FGAC 3THNA 3IVEA 4IYPC
chains in the Genus database with same CATH superfamily
4ORAA 5F3WA 2O8GA 2NXFA 1S95A 4V0VA 5GTUA 4H2IA 3V4YA 2NYMC 1T70A 4O24A 3H60A 3QFNA 3H66A 1S70A 3H63A 2QFRA 2JOGA 2WDEA 3AV0A 4DSYA 3RL4A 2A22A 1XZWA 3E0JA 3EGGA 1USHA 2Q8UA 1HP1A 1HPUA 1FJMA 1JK7A 3HVQA 1WAO1 2GJUA 2HY1A 4JA9A 2WDFA 5INBA 3E7AA 2Z1AA 3FLOA 3P71C 3T1IA 2DFJA 4HD0A 2XMOA 4ORBA 1S3MA 2BCDA 3DW8C 1QFCA 3RL3A 2Z06A 3EGHA 4FBQA 4LACC 3K7VC 4H2FA 1QHWA 2BDXA 3N5UA 4ORCA 3THOB 5IOHA 4NZVA 4UT3B 4YKEA 4V0XA 1S3NA 2YEQA 3DSDA 1II7A 4IL1A 4DHLA 4FCXA 1SU1A 1T71A 3IVDA 4I5LC 4DT2A 1S8EA 3K7WC 4FBWA 2O8AA 5EQVA 4B2OA 1S3LA 1Z2WA 4TUGA 4G9JA 1KBPA 2NYLC 3PSNA 3ZTVA 4M0VA 3H69A 2HYPA 1AUIA 3GVEA 3JYFA 4UWQA 4MOVA 4ZX2A 1WARA 2DXNA 1UTEA 2ZO9B 3KBPA 3CK2A 4Q7FA 3PSOA 4LU9A 3E7BA 2QJCA 1G5BA 3H67A 3RL5A 2AHDA 3RQZA 3TGHA 1MF8A 1HO5A 4V0WA 1XM7A 4LTYA 5JPEA 1UF3A 3H64A 3QFOA 5JJTA 2WDDA 4H2BA 1NNWA 4O5GA 3H62B 3H68A 1TCOA 3H61A 2ZOAA 3LL8A 4KBPA 4UT2A 4O4KA 4FBKA 4KKZA 3QFMA 1Z2XA 2YVTA 2QFPA 2CV9A 3D03A 3C9FA 4H1YP 2DXLA 2IE3C 1IT6A 2NPPC 4O43A 4H1SA 1OI8A 1M63A 2R17A 1V73A 1W24A 2WDCA 3C5WC 2IE4C 4JA7A 5B8IA 1OIDA 4MP0A 5JPFA 3ZU0A 4UT3A 2BQ8X 4OR9A 4XPNA 5C1VA 4WWLA 5HPEA 5J28A 4ZVZA 4H2GA 4J6OA 4I5NC 3DSCA 2KKNA 3AUZA 5DNYA 2P6BA 2USHA 4F0ZA 2Z72A 3IB8A 4MOYA 2IAEC 1OIEA 2ZBMA 2HYOA 1U32A 3QFKA 4TUIA 3IB7A 3ICFA 3QG5C 3FGAC 3THNA 3IVEA 4IYPC
chains in the Genus database with same CATH topology
4ORAA 5F3WA 2O8GA 2NXFA 1S95A 4V0VA 5GTUA 4H2IA 3V4YA 2NYMC 1T70A 4O24A 3H60A 3QFNA 3H66A 1S70A 3H63A 2QFRA 2JOGA 2WDEA 3AV0A 4DSYA 3RL4A 2A22A 1XZWA 3E0JA 3EGGA 1USHA 2Q8UA 1HP1A 1HPUA 1FJMA 1JK7A 3HVQA 1WAO1 2GJUA 2HY1A 4JA9A 2WDFA 5INBA 3E7AA 2Z1AA 3FLOA 3P71C 3T1IA 2DFJA 4HD0A 2XMOA 4ORBA 1S3MA 2BCDA 3DW8C 1QFCA 3RL3A 2Z06A 3EGHA 4FBQA 4LACC 3K7VC 4H2FA 1QHWA 2BDXA 3N5UA 4ORCA 3THOB 5IOHA 4NZVA 4UT3B 4YKEA 4V0XA 1S3NA 2YEQA 3DSDA 1II7A 4IL1A 4DHLA 4FCXA 1SU1A 1T71A 3IVDA 4I5LC 4DT2A 1S8EA 3K7WC 4FBWA 2O8AA 5EQVA 4B2OA 1S3LA 1Z2WA 4TUGA 4G9JA 1KBPA 2NYLC 3PSNA 3ZTVA 4M0VA 3H69A 2HYPA 1AUIA 3GVEA 3JYFA 4UWQA 4MOVA 4ZX2A 1WARA 2DXNA 1UTEA 2ZO9B 3KBPA 3CK2A 4Q7FA 3PSOA 4LU9A 3E7BA 2QJCA 1G5BA 3H67A 3RL5A 2AHDA 3RQZA 3TGHA 1MF8A 1HO5A 4V0WA 1XM7A 4LTYA 5JPEA 1UF3A 3H64A 3QFOA 5JJTA 2WDDA 4H2BA 1NNWA 4O5GA 3H62B 3H68A 1TCOA 3H61A 2ZOAA 3LL8A 4KBPA 4UT2A 4O4KA 4FBKA 4KKZA 3QFMA 1Z2XA 2YVTA 2QFPA 2CV9A 3D03A 3C9FA 4H1YP 2DXLA 2IE3C 1IT6A 2NPPC 4O43A 4H1SA 1OI8A 1M63A 2R17A 1V73A 1W24A 2WDCA 3C5WC 2IE4C 4JA7A 5B8IA 1OIDA 4MP0A 5JPFA 3ZU0A 4UT3A 2BQ8X 4OR9A 4XPNA 5C1VA 4WWLA 5HPEA 5J28A 4ZVZA 4H2GA 4J6OA 4I5NC 3DSCA 2KKNA 3AUZA 5DNYA 2P6BA 2USHA 4F0ZA 2Z72A 3IB8A 4MOYA 2IAEC 1OIEA 2ZBMA 2HYOA 1U32A 3QFKA 4TUIA 3IB7A 3ICFA 3QG5C 3FGAC 3THNA 3IVEA 4IYPC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4ORA A;  5F3W A;  2O8G A;  2NXF A;  1S95 A;  4V0V A;  5GTU A;  4H2I A;  3V4Y A;  2NYM C;  1T70 A;  4O24 A;  3H60 A;  3H66 A;  1S70 A;  3H63 A;  2QFR A;  2JOG A;  2WDE A;  3AV0 A;  4DSY A;  3RL4 A;  2A22 A;  1XZW A;  3QFN A;  3EGG A;  1USH A;  2Q8U A;  1HP1 A;  1HPU A;  1FJM A;  1JK7 A;  3HVQ A;  1WAO 1;  2GJU A;  2HY1 A;  4JA9 A;  2WDF A;  5INB A;  3E7A A;  2Z1A A;  3P71 C;  3T1I A;  2DFJ A;  4HD0 A;  2XMO A;  4ORB A;  1S3M A;  2BCD A;  3DW8 C;  1QFC A;  3RL3 A;  2Z06 A;  3EGH A;  4FBQ A;  4LAC C;  3K7V C;  4H2F A;  1QHW A;  2BDX A;  3N5U A;  4ORC A;  3THO B;  5IOH A;  4NZV A;  4UT3 B;  4YKE A;  4V0X A;  1S3N A;  3DSD A;  1II7 A;  4IL1 A;  4DHL A;  4FCX A;  1SU1 A;  1T71 A;  3IVD A;  4I5L C;  4DT2 A;  1S8E A;  3K7W C;  4FBW A;  2O8A A;  5EQV A;  4B2O A;  1S3L A;  1Z2W A;  4TUG A;  4G9J A;  1KBP A;  2NYL C;  3PSN A;  3ZTV A;  4M0V A;  3H69 A;  2HYP A;  1AUI A;  3GVE A;  3JYF A;  4UWQ A;  4MOV A;  4ZX2 A;  1WAR A;  1UTE A;  3KBP A;  3CK2 A;  4Q7F A;  3PSO A;  4LU9 A;  3E7B A;  2QJC A;  1G5B A;  3H67 A;  3RL5 A;  2AHD A;  3RQZ A;  3TGH A;  1MF8 A;  1HO5 A;  4V0W A;  1XM7 A;  4LTY A;  5JPE A;  1UF3 A;  3H64 A;  3QFO A;  5JJT A;  2WDD A;  4H2B A;  1NNW A;  4O5G A;  3H62 B;  3H68 A;  1TCO A;  3H61 A;  3LL8 A;  4KBP A;  4UT2 A;  4O4K A;  4FBK A;  4KKZ A;  3QFM A;  1Z2X A;  2YVT A;  2QFP A;  2CV9 A;  3C9F A;  4H1Y P;  2IE3 C;  2NPP C;  1IT6 A;  4O43 A;  4H1S A;  1OI8 A;  1M63 A;  2R17 A;  1V73 A;  1W24 A;  2WDC A;  3C5W C;  2IE4 C;  4JA7 A;  5B8I A;  1OID A;  4MP0 A;  5JPF A;  3ZU0 A;  4UT3 A;  2BQ8 X;  4OR9 A;  4XPN A;  5C1V A;  4WWL A;  5HPE A;  5J28 A;  4ZVZ A;  4H2G A;  4J6O A;  4I5N C;  3DSC A;  2KKN A;  3AUZ A;  5DNY A;  2P6B A;  2USH A;  4F0Z A;  2Z72 A;  3IB8 A;  4MOY A;  2IAE C;  1OIE A;  2ZBM A;  2HYO A;  1U32 A;  3QFK A;  4TUI A;  3IB7 A;  3ICF A;  3QG5 C;  3FGA C;  3THN A;  3IVE A;  4IYP C; 
#chains in the Genus database with same CATH topology
 4ORA A;  5F3W A;  2O8G A;  2NXF A;  1S95 A;  4V0V A;  5GTU A;  4H2I A;  3V4Y A;  2NYM C;  1T70 A;  4O24 A;  3H60 A;  3QFN A;  3H66 A;  1S70 A;  3H63 A;  2QFR A;  2JOG A;  2WDE A;  3AV0 A;  4DSY A;  3RL4 A;  2A22 A;  1XZW A;  3E0J A;  3EGG A;  1USH A;  2Q8U A;  1HP1 A;  1HPU A;  1FJM A;  1JK7 A;  3HVQ A;  1WAO 1;  2GJU A;  2HY1 A;  4JA9 A;  2WDF A;  5INB A;  3E7A A;  2Z1A A;  3FLO A;  3P71 C;  3T1I A;  2DFJ A;  4HD0 A;  2XMO A;  4ORB A;  1S3M A;  2BCD A;  3DW8 C;  1QFC A;  3RL3 A;  2Z06 A;  3EGH A;  4FBQ A;  4LAC C;  3K7V C;  4H2F A;  1QHW A;  2BDX A;  3N5U A;  4ORC A;  3THO B;  5IOH A;  4NZV A;  4UT3 B;  4YKE A;  4V0X A;  1S3N A;  2YEQ A;  3DSD A;  1II7 A;  4IL1 A;  4DHL A;  4FCX A;  1SU1 A;  1T71 A;  3IVD A;  4I5L C;  4DT2 A;  1S8E A;  3K7W C;  4FBW A;  2O8A A;  5EQV A;  4B2O A;  1S3L A;  1Z2W A;  4TUG A;  4G9J A;  1KBP A;  2NYL C;  3PSN A;  3ZTV A;  4M0V A;  3H69 A;  2HYP A;  1AUI A;  3GVE A;  3JYF A;  4UWQ A;  4MOV A;  4ZX2 A;  1WAR A;  2DXN A;  1UTE A;  2ZO9 B;  3KBP A;  3CK2 A;  4Q7F A;  3PSO A;  4LU9 A;  3E7B A;  2QJC A;  1G5B A;  3H67 A;  3RL5 A;  2AHD A;  3RQZ A;  3TGH A;  1MF8 A;  1HO5 A;  4V0W A;  1XM7 A;  4LTY A;  5JPE A;  1UF3 A;  3H64 A;  3QFO A;  5JJT A;  2WDD A;  4H2B A;  1NNW A;  4O5G A;  3H62 B;  3H68 A;  1TCO A;  3H61 A;  2ZOA A;  3LL8 A;  4KBP A;  4UT2 A;  4O4K A;  4FBK A;  4KKZ A;  3QFM A;  1Z2X A;  2YVT A;  2QFP A;  2CV9 A;  3D03 A;  3C9F A;  4H1Y P;  2DXL A;  2IE3 C;  1IT6 A;  2NPP C;  4O43 A;  4H1S A;  1OI8 A;  1M63 A;  2R17 A;  1V73 A;  1W24 A;  2WDC A;  3C5W C;  2IE4 C;  4JA7 A;  5B8I A;  1OID A;  4MP0 A;  5JPF A;  3ZU0 A;  4UT3 A;  2BQ8 X;  4OR9 A;  4XPN A;  5C1V A;  4WWL A;  5HPE A;  5J28 A;  4ZVZ A;  4H2G A;  4J6O A;  4I5N C;  3DSC A;  2KKN A;  3AUZ A;  5DNY A;  2P6B A;  2USH A;  4F0Z A;  2Z72 A;  3IB8 A;  4MOY A;  2IAE C;  1OIE A;  2ZBM A;  2HYO A;  1U32 A;  3QFK A;  4TUI A;  3IB7 A;  3ICF A;  3QG5 C;  3FGA C;  3THN A;  3IVE A;  4IYP C; 
#chains in the Genus database with same CATH homology
 4ORA A;  5F3W A;  2O8G A;  2NXF A;  1S95 A;  4V0V A;  5GTU A;  4H2I A;  3V4Y A;  2NYM C;  1T70 A;  4O24 A;  3H60 A;  3QFN A;  3H66 A;  1S70 A;  3H63 A;  2QFR A;  2JOG A;  2WDE A;  3AV0 A;  4DSY A;  3RL4 A;  2A22 A;  1XZW A;  3E0J A;  3EGG A;  1USH A;  2Q8U A;  1HP1 A;  1HPU A;  1FJM A;  1JK7 A;  3HVQ A;  1WAO 1;  2GJU A;  2HY1 A;  4JA9 A;  2WDF A;  5INB A;  3E7A A;  2Z1A A;  3FLO A;  3P71 C;  3T1I A;  2DFJ A;  4HD0 A;  2XMO A;  4ORB A;  1S3M A;  2BCD A;  3DW8 C;  1QFC A;  3RL3 A;  2Z06 A;  3EGH A;  4FBQ A;  4LAC C;  3K7V C;  4H2F A;  1QHW A;  2BDX A;  3N5U A;  4ORC A;  3THO B;  5IOH A;  4NZV A;  4UT3 B;  4YKE A;  4V0X A;  1S3N A;  2YEQ A;  3DSD A;  1II7 A;  4IL1 A;  4DHL A;  4FCX A;  1SU1 A;  1T71 A;  3IVD A;  4I5L C;  4DT2 A;  1S8E A;  3K7W C;  4FBW A;  2O8A A;  5EQV A;  4B2O A;  1S3L A;  1Z2W A;  4TUG A;  4G9J A;  1KBP A;  2NYL C;  3PSN A;  3ZTV A;  4M0V A;  3H69 A;  2HYP A;  1AUI A;  3GVE A;  3JYF A;  4UWQ A;  4MOV A;  4ZX2 A;  1WAR A;  2DXN A;  1UTE A;  2ZO9 B;  3KBP A;  3CK2 A;  4Q7F A;  3PSO A;  4LU9 A;  3E7B A;  2QJC A;  1G5B A;  3H67 A;  3RL5 A;  2AHD A;  3RQZ A;  3TGH A;  1MF8 A;  1HO5 A;  4V0W A;  1XM7 A;  4LTY A;  5JPE A;  1UF3 A;  3H64 A;  3QFO A;  5JJT A;  2WDD A;  4H2B A;  1NNW A;  4O5G A;  3H62 B;  3H68 A;  1TCO A;  3H61 A;  2ZOA A;  3LL8 A;  4KBP A;  4UT2 A;  4O4K A;  4FBK A;  4KKZ A;  3QFM A;  1Z2X A;  2YVT A;  2QFP A;  2CV9 A;  3D03 A;  3C9F A;  4H1Y P;  2DXL A;  2IE3 C;  1IT6 A;  2NPP C;  4O43 A;  4H1S A;  1OI8 A;  1M63 A;  2R17 A;  1V73 A;  1W24 A;  2WDC A;  3C5W C;  2IE4 C;  4JA7 A;  5B8I A;  1OID A;  4MP0 A;  5JPF A;  3ZU0 A;  4UT3 A;  2BQ8 X;  4OR9 A;  4XPN A;  5C1V A;  4WWL A;  5HPE A;  5J28 A;  4ZVZ A;  4H2G A;  4J6O A;  4I5N C;  3DSC A;  2KKN A;  3AUZ A;  5DNY A;  2P6B A;  2USH A;  4F0Z A;  2Z72 A;  3IB8 A;  4MOY A;  2IAE C;  1OIE A;  2ZBM A;  2HYO A;  1U32 A;  3QFK A;  4TUI A;  3IB7 A;  3ICF A;  3QG5 C;  3FGA C;  3THN A;  3IVE A;  4IYP C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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