3RV1A

Crystal structure of the n-terminal and rnase iii domains of k. polysporus dcr1 e224q mutant
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
242
structure length
217
Chain Sequence
SNELKVREFYRLHNACVKLKESIKLIYENPLVTDQNVLNLGTAENTIDYTILNTPTLNVAKTLLGNRYSLDLIDLFQSHDFKDSNTDVDMFIKYPVVYDENLENLAFMHKSQLSNERLEFLGDSWLGALVSYIVYTRFPSANEGMLSQMKESIVNNNNLFDWSTKLNFTKRLQGNIAKRYADCVQAYIGALVIDRFGTEFLDIKEWLEELSEKKLAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The inside-out mechanism of dicers from budding yeasts.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Vanderwaltozyma polyspora
molecule keywords K. polysporus Dcr1
total genus 79
structure length 217
sequence length 242
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00636 Ribonuclease_3 Ribonuclease III domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1520.10 Mainly Alpha Orthogonal Bundle Ribonuclease iii, N-terminal Endonuclease Domain; Chain A Ribonuclease III domain 3rv1A02
1.20.1270.260 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 3rv1A01
2NUEA 3N3WA 1I4SA 1RC5A 3RV1A 4OOGC 1RC7A 4M30A 2EB1A 1YYWA 1JFZA 2FFLA 1YZ9A 2GSLA 1O0WA 2NUGA 2EZ6A 3O2RA 3RV0A 2A11A 3C4BA 4OUNA 1YYKA 3O2RB 2QVWA 3C4TA 4M2ZA 1YYOA 2NUFA 1U61A
chains in the Genus database with same CATH superfamily
4EZVA 2F18A 2X3XA 3DDFA 1U00A 4JNFA 1R33A 2GA9D 2GSLA 4IW0A 4ATMA 3O2RA 1E2UA 4I1QA 1OAOA 4AVMA 2RAKA 2OBLA 3SYVA 1QWNA 2ELBA 3HAHA 2Z0NA 4R5KA 1OA1A 1DKXA 4H6HA 4H8SA 2Z0VA 3BUIA 2F1BA 4FZSA 4IM2A 2YIAA 3KDRA 2QFFA 2YI8A 4EZPA 2NCZA 4M0MA 3L3PA 3D51A 3BVVA 1UPXA 4JLCA 4KIKA 2KHOA 1LQ7A 3EJUA 1ZWWA 4AZBA 2D1LA 4JN4A 1Y2OA 3T4AG 3QWEA 2YLLA 1E9VA 4D8JA 4OUNA 3A98A 3Q0KA 2YL6A 3F7WA 3SOGA 4R5JA 4AZHA 2Q12A 3L3OM 3I01A 3D50A 3I04A 4EZYA 4AZ7A 3BUQA 2EZ6A 3RV0A 1E1DA 2LM0A 4IWPA 2YL9A 2F7QA 4EZUA 2EFKA 1YYOA 1HTYA 1WDZA 3QE6A 3OK8A 2V0OA 4IWQA 4EZQA 2OO2A 1ZYLA 4UDYX 2YIBA 4IWOA 4WPEA 2D4CA 3VEAA 2C08A 2PY6A 3ER8C 3GI7A 1TQVA 1HWWA 1MJGA 4JWCA 4EZXA 2NUFA 3T46A 5KBPA 3VEBA 2NUEA 1ZTDA 4HR1A 3DPQA 1RC7A 3ERCC 3I39X 3PLTA 1X03A 2JNSA 2OBMA 5E84A 3G9GA 3D4ZA 4EZZA 4AZ5A 2QVWA 3ACOA 1HXKA 3DPPA 2RAJA 4AZCA 5C5BA 4NQIA 1U61A 4EZOA 4EZNA 1I4TA 3B52X 3T48A 3CKDA 1YYWA 3BLBA 4NPHA 1GNTA 3T47A 4FM3A 3I2WA 3BVTA 5FLEX 1PS3A 3BUPA 3D2FA 1I4SA 3CAZA 4OOGC 3CV5A 1SU8A 2EB1A 4EZWA 2OW7A 1O0WA 2F1AA 2RT6A 2RAIA 3LLLA 4JNEA 2FYVA 2ZXQA 2F7RA 3LMFA 3LVTA 2WYHA 3RPMA 3EJRA 2PMRA 4R5LA 3T49A 3RV1A 3VKHA 4JL9A 1JFZA 4AZ6A 2YIVX 3C7NA 3Q84A 3EJSA 1SUFA 1URUA 2ND1A 3QA8A 4F00A 2GF4A 2Q13A 2OZNB 4HR1B 1SU6A 1YZ9A 4IM3A 4G6QA 1TQUA 4F01A 3O2RB 3O3MB 3O3NB 2YL5A 2OW6A 2EX3B 1R5EA 2QKWA 3UITA 3ER9B 3DX1A 2F7OA 4NSWA 1JQKA 4BNEA 4E3CA 2X3WA 4JWDA 4EZSA 1I4LA 3DDGA 3M3WA 1X04A 1GNLA 2YLAA 1O7DB 4UDXX 1O7DC 4B9QA 2Z8YA 1TQTA 1SU7A 4E81A 3EJTA 3BVXA 3QNJA 2EFLA 4KIKB 4DCNC 1R34A 3ABHA 2FICA 1YWMA 1QX1A 1I49A 3BUDA 3D52A 4R5IA 4JWIA 3D2EA 2X3VA 4M2ZA 2MI7A 2WYIA 3D4YA 3N3WA 3B51X 3EJPA 3DX4A 3B53X 3HAJA 2JNKA 2QXLA 2F7PA 3OHXM 3ZEDA 1GN9A 1DKZA 3DX3A 4DYLA 3DPOA 4HY9A 1TQWA 4M30A 3O3OB 3DX2A 4EZRA 4JWEA 3BVWA 4WPCA 2NUGA 2YL8A 3KAWA 1YYKA 4AKVA 3CVRA 4AZIA 1W9MA 2LXYA 2X5CA 3FD9A 3BUBA 2GAFD 2O0I1 3DX0A 2N3KA 1OA0A 2EWFA 4HYBA 1TQSA 2A11A 3C4BA 3C4TA 2ALWA 2Z0OA 3KAVA 2WINM 4FZOA 4EZTA 1I4DA 4PO2A 4AZCB 5C5BB 1QWUA 1RC5A 2YKTA 3DYTA 2ND0A 3CZNA 2FFLA 3QNIA 4IM0A 5TKYA 4R5GA 5FIGA 3OWGA 3BVUA 1DKYA 3CZSA 2YI9A 4AZGA 3HAIA 4H6IA 4FZPA 3EJQA
chains in the Genus database with same CATH topology
4R5LA 4EZVA 3N3WA 3B51X 4IWQA 1U00A 3T49A 3RV1A 4JNFA 3VKHA 4JL9A 4EZQA 4UDYX 1ZYLA 1JFZA 2GA9D 2YIVX 3B53X 2YIBA 4IWOA 2GSLA 3C7NA 3VEAA 4IW0A 2PY6A 3ER8C 3O2RA 1E2UA 3GI7A 2QXLA 3OHXM 1OAOA 3ZEDA 1GN9A 1DKZA 2OBLA 1MJGA 4JWCA 1SUFA 4EZXA 2ND1A 2NUFA 3T46A 3QA8A 4F00A 4R5KA 3VEBA 2NUEA 3DPOA 4HR1A 1OA1A 4HY9A 1DKXA 4HR1B 3DPQA 1RC7A 4H6HA 4M30A 3O3OB 1SU6A 3ERCC 3I39X 4JWEA 4EZRA 1YZ9A 4IM3A 2JNSA 4IM2A 2OBMA 5E84A 2YIAA 2NUGA 3KDRA 2QFFA 4G6QA 4F01A 2YI8A 4EZZA 4EZPA 3KAWA 1YYKA 3O2RB 2QVWA 3O3MB 2NCZA 3O3NB 4M0MA 3DPPA 1W9MA 2EX3B 1U61A 2X5CA 1UPXA 3FD9A 3UITA 3ER9B 4EZOA 4JLCA 2GAFD 4KIKA 4EZNA 3B52X 2KHOA 3T48A 2N3KA 1YYWA 1JQKA 1OA0A 4JN4A 3T4AG 2EWFA 4HYBA 4E3CA 4NPHA 1E9VA 4JWDA 4EZSA 4D8JA 2A11A 3C4BA 4OUNA 1GNTA 4FM3A 3T47A 3A98A 3C4TA 1GNLA 3F7WA 4UDXX 3KAVA 2WINM 5FLEX 4B9QA 4EZTA 4R5JA 2Z8YA 4PO2A 3D2FA 1I4SA 1SU7A 4E81A 3L3OM 1RC5A 4OOGC 3I01A 1SU8A 3QNJA 3I04A 2ND0A 2EB1A 4KIKB 2FFLA 4EZWA 4EZYA 4IM0A 5TKYA 1O0WA 2EZ6A 3RV0A 2RT6A 4JNEA 4R5GA 5FIGA 3OWGA 1E1DA 2LM0A 4R5IA 4IWPA 4JWIA 3D2EA 1DKYA 4EZUA 2YI9A 4M2ZA 1YYOA 4H6IA 3LMFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NUE A;  3N3W A;  1I4S A;  1RC5 A;  3RV1 A;  4OOG C;  1RC7 A;  4M30 A;  2EB1 A;  1YYW A;  1JFZ A;  2FFL A;  1YZ9 A;  2GSL A;  1O0W A;  2NUG A;  2EZ6 A;  3O2R A;  3RV0 A;  2A11 A;  3C4B A;  4OUN A;  1YYK A;  3O2R B;  2QVW A;  3C4T A;  4M2Z A;  1YYO A;  2NUF A;  1U61 A; 
#chains in the Genus database with same CATH topology
 4EZV A;  2F18 A;  2X3X A;  3DDF A;  1U00 A;  4JNF A;  1R33 A;  2GA9 D;  2GSL A;  4IW0 A;  4ATM A;  3O2R A;  1E2U A;  4I1Q A;  1OAO A;  4AVM A;  2RAK A;  2OBL A;  3SYV A;  1QWN A;  2ELB A;  3HAH A;  2Z0N A;  4R5K A;  1OA1 A;  1DKX A;  4H6H A;  4H8S A;  2Z0V A;  3BUI A;  2F1B A;  4FZS A;  4IM2 A;  2YIA A;  3KDR A;  2QFF A;  2YI8 A;  4EZP A;  2NCZ A;  4M0M A;  3L3P A;  3D51 A;  3BVV A;  1UPX A;  4JLC A;  4KIK A;  2KHO A;  1LQ7 A;  3EJU A;  1ZWW A;  4AZB A;  2D1L A;  4JN4 A;  1Y2O A;  3T4A G;  3QWE A;  2YLL A;  1E9V A;  4D8J A;  4OUN A;  3A98 A;  3Q0K A;  2YL6 A;  3F7W A;  3SOG A;  4R5J A;  4AZH A;  2Q12 A;  3L3O M;  3I01 A;  3D50 A;  3I04 A;  4EZY A;  4AZ7 A;  3BUQ A;  2EZ6 A;  3RV0 A;  1E1D A;  2LM0 A;  4IWP A;  2YL9 A;  2F7Q A;  4EZU A;  2EFK A;  1YYO A;  1HTY A;  1WDZ A;  3QE6 A;  3OK8 A;  2V0O A;  4IWQ A;  4EZQ A;  2OO2 A;  1ZYL A;  4UDY X;  2YIB A;  4IWO A;  4WPE A;  2D4C A;  3VEA A;  2C08 A;  2PY6 A;  3ER8 C;  3GI7 A;  1TQV A;  1HWW A;  1MJG A;  4JWC A;  4EZX A;  2NUF A;  3T46 A;  5KBP A;  3VEB A;  2NUE A;  1ZTD A;  4HR1 A;  3DPQ A;  1RC7 A;  3ERC C;  3I39 X;  3PLT A;  1X03 A;  2JNS A;  2OBM A;  5E84 A;  3G9G A;  3D4Z A;  4EZZ A;  4AZ5 A;  2QVW A;  3ACO A;  1HXK A;  3DPP A;  2RAJ A;  4AZC A;  5C5B A;  4NQI A;  1U61 A;  4EZO A;  4EZN A;  1I4T A;  3B52 X;  3T48 A;  3CKD A;  1YYW A;  3BLB A;  4NPH A;  1GNT A;  3T47 A;  4FM3 A;  3I2W A;  3BVT A;  5FLE X;  1PS3 A;  3BUP A;  3D2F A;  1I4S A;  3CAZ A;  4OOG C;  3CV5 A;  1SU8 A;  2EB1 A;  4EZW A;  2OW7 A;  1O0W A;  2F1A A;  2RT6 A;  2RAI A;  3LLL A;  4JNE A;  2FYV A;  2ZXQ A;  2F7R A;  3LMF A;  3LVT A;  2WYH A;  3RPM A;  3EJR A;  2PMR A;  4R5L A;  3T49 A;  3RV1 A;  3VKH A;  4JL9 A;  1JFZ A;  4AZ6 A;  2YIV X;  3C7N A;  3Q84 A;  3EJS A;  1SUF A;  1URU A;  2ND1 A;  3QA8 A;  4F00 A;  2GF4 A;  2Q13 A;  2OZN B;  4HR1 B;  1SU6 A;  1YZ9 A;  4IM3 A;  4G6Q A;  1TQU A;  4F01 A;  3O2R B;  3O3M B;  3O3N B;  2YL5 A;  2OW6 A;  2EX3 B;  1R5E A;  2QKW A;  3UIT A;  3ER9 B;  3DX1 A;  2F7O A;  4NSW A;  1JQK A;  4BNE A;  4E3C A;  2X3W A;  4JWD A;  4EZS A;  1I4L A;  3DDG A;  3M3W A;  1X04 A;  1GNL A;  2YLA A;  1O7D B;  4UDX X;  1O7D C;  4B9Q A;  2Z8Y A;  1TQT A;  1SU7 A;  4E81 A;  3EJT A;  3BVX A;  3QNJ A;  2EFL A;  4KIK B;  4DCN C;  1R34 A;  3ABH A;  2FIC A;  1YWM A;  1QX1 A;  1I49 A;  3BUD A;  3D52 A;  4R5I A;  4JWI A;  3D2E A;  2X3V A;  4M2Z A;  2MI7 A;  2WYI A;  3D4Y A;  3N3W A;  3B51 X;  3EJP A;  3DX4 A;  3B53 X;  3HAJ A;  2JNK A;  2QXL A;  2F7P A;  3OHX M;  3ZED A;  1GN9 A;  1DKZ A;  3DX3 A;  4DYL A;  3DPO A;  4HY9 A;  1TQW A;  4M30 A;  3O3O B;  3DX2 A;  4EZR A;  4JWE A;  3BVW A;  4WPC A;  2NUG A;  2YL8 A;  3KAW A;  1YYK A;  4AKV A;  3CVR A;  4AZI A;  1W9M A;  2LXY A;  2X5C A;  3FD9 A;  3BUB A;  2GAF D;  2O0I 1;  3DX0 A;  2N3K A;  1OA0 A;  2EWF A;  4HYB A;  1TQS A;  2A11 A;  3C4B A;  3C4T A;  2ALW A;  2Z0O A;  3KAV A;  2WIN M;  4FZO A;  4EZT A;  1I4D A;  4PO2 A;  4AZC B;  5C5B B;  1QWU A;  1RC5 A;  2YKT A;  3DYT A;  2ND0 A;  3CZN A;  2FFL A;  3QNI A;  4IM0 A;  5TKY A;  4R5G A;  5FIG A;  3OWG A;  3BVU A;  1DKY A;  3CZS A;  2YI9 A;  4AZG A;  3HAI A;  4H6I A;  4FZP A;  3EJQ A; 
#chains in the Genus database with same CATH homology
 4R5L A;  4EZV A;  3N3W A;  3B51 X;  4IWQ A;  1U00 A;  3T49 A;  3RV1 A;  4JNF A;  3VKH A;  4JL9 A;  4EZQ A;  4UDY X;  1ZYL A;  1JFZ A;  2GA9 D;  2YIV X;  3B53 X;  2YIB A;  4IWO A;  2GSL A;  3C7N A;  3VEA A;  4IW0 A;  2PY6 A;  3ER8 C;  3O2R A;  1E2U A;  3GI7 A;  2QXL A;  3OHX M;  1OAO A;  3ZED A;  1GN9 A;  1DKZ A;  2OBL A;  1MJG A;  4JWC A;  1SUF A;  4EZX A;  2ND1 A;  2NUF A;  3T46 A;  3QA8 A;  4F00 A;  4R5K A;  3VEB A;  2NUE A;  3DPO A;  4HR1 A;  1OA1 A;  4HY9 A;  1DKX A;  4HR1 B;  3DPQ A;  1RC7 A;  4H6H A;  4M30 A;  3O3O B;  1SU6 A;  3ERC C;  3I39 X;  4JWE A;  4EZR A;  1YZ9 A;  4IM3 A;  2JNS A;  4IM2 A;  2OBM A;  5E84 A;  2YIA A;  2NUG A;  3KDR A;  2QFF A;  4G6Q A;  4F01 A;  2YI8 A;  4EZZ A;  4EZP A;  3KAW A;  1YYK A;  3O2R B;  2QVW A;  3O3M B;  2NCZ A;  3O3N B;  4M0M A;  3DPP A;  1W9M A;  2EX3 B;  1U61 A;  2X5C A;  1UPX A;  3FD9 A;  3UIT A;  3ER9 B;  4EZO A;  4JLC A;  2GAF D;  4KIK A;  4EZN A;  3B52 X;  2KHO A;  3T48 A;  2N3K A;  1YYW A;  1JQK A;  1OA0 A;  4JN4 A;  3T4A G;  2EWF A;  4HYB A;  4E3C A;  4NPH A;  1E9V A;  4JWD A;  4EZS A;  4D8J A;  2A11 A;  3C4B A;  4OUN A;  1GNT A;  4FM3 A;  3T47 A;  3A98 A;  3C4T A;  1GNL A;  3F7W A;  4UDX X;  3KAV A;  2WIN M;  5FLE X;  4B9Q A;  4EZT A;  4R5J A;  2Z8Y A;  4PO2 A;  3D2F A;  1I4S A;  1SU7 A;  4E81 A;  3L3O M;  1RC5 A;  4OOG C;  3I01 A;  1SU8 A;  3QNJ A;  3I04 A;  2ND0 A;  2EB1 A;  4KIK B;  2FFL A;  4EZW A;  4EZY A;  4IM0 A;  5TKY A;  1O0W A;  2EZ6 A;  3RV0 A;  2RT6 A;  4JNE A;  4R5G A;  5FIG A;  3OWG A;  1E1D A;  2LM0 A;  4R5I A;  4IWP A;  4JWI A;  3D2E A;  1DKY A;  4EZU A;  2YI9 A;  4M2Z A;  1YYO A;  4H6I A;  3LMF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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