3SWOA

Crystal structure of a glutaryl-coa dehydrogenase from mycobacterium smegmatis in complex with fadh2
Total Genus 155
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
155
sequence length
388
structure length
388
Chain Sequence
KSTYAPLELFDTDRLLDQDERDIAATVRQFVDTRLKPNVEGWFESATLPSELAKEFGNLGVLGMHLQGYGCAGTNAVSYGLACMELEAGDSGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGLTEPDFGSNPAGMRTRARRDGSDWILNGTKMWITNGNLADVATVWAQTDDGIRGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQLPLAEGLSAPLSCLNEARFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQEKLANMTVELGKGMLLAIHLGRIKDAEGVRPEQISLGKLNNVREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLTYEGTSEMHLLSIGKALTGKAAFR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
source organism Mycobacterium smegmatis
molecule tags Oxidoreductase
molecule keywords Glutaryl-CoA dehydrogenase
total genus 155
structure length 388
sequence length 388
chains with identical sequence B, C, D
ec nomenclature ec 1.3.99.7: Transferred entry: 1.3.8.6.
pdb deposition date 2011-07-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3swoA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3swoA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3swoA02
5K3GA 3NF4A 4G5EA 3L1TA 4OO2A 2VIGA 2RDZA 2YYIA 3X0YA 2JBRA 2C0UA 4KTOA 3GQTA 1IVHA 1JQIA 4HR3A 1FS8A 1IS2A 3FO3A 2EBAA 2C12A 4RM7A 3D9EA 4DOYA 3EONA 2PG0A 1EGCA 4L3YA 2OR0A 3TORA 3MXLA 2WBIA 2DDHA 4U83A 2E81A 2RFQA 2REHA 3RKHA 3F29A 3EOMA 3OWAA 4X28C 3SXQA 1EGEA 3MDEA 4WJYA 4XVXA 2JBSA 3AFEA 2CX9A 3GM6A 4N5FA 3BNHA 4W9UA 4Q5BA 1T9GA 3D1IA 4L1FA 2ZO5A 1OAHA 2JIFA 2R0MA 2RF7A 3OWMA 4NXLA 3TTBA 2R0NA 4IV6A 4Q17A 1EGDA 4M9AA 4ZXVA 3BNJA 3FCJA 3BNFA 3D9DA 3SCEA 1U8VA 2FONA 2YYJA 3S7WA 3D9FA 3MPJA 1BUCA 3GNCA 2YYLA 2Z1QA 1FS9A 5K3HA 3B96A 4L3ZA 3SWOA 1W07A 1RX0A 4KCFA 2D29A 2YYGA 3AFFA 5K3JA 2OT4A 3II9A 5K3IA 2IX6A 3MMOA 3UU9A 2YYKA 3HWCA 4JEKA 4ZYJA 2A1TA 2E80A 3MPIA 4P13A 2ZAFA 3UBRA 4Q1OA 4Q0TA 1UKWA 2DVLA 2JBTA 2J7AA 3PFDA 4L38A 1GU6A 1QDBA 2UXWA 3SF6A 1WS9A 1FS7A 2IX5A 3R7KA 3P4TA 3D9GA 4O5MA 4X28A 3LGQA 2VR0A 3BNGA 3MDDA 4Q5CA 3X0XA 3D6BA 1SIQA 4IRNA 3M9VA 3LG1A 3MKHA 1R2JA 3OIBA 1UDYA 4L3XA 4Q4UA 2YYMA 1SIRA
chains in the Genus database with same CATH superfamily
5K3GA 3NF4A 2Q8FA 4P79A 4G5EA 3L1TA 1Y8OA 4OO2A 3VADA 2VIGA 1K8TA 1SC5A 2RDZA 2YYIA 3X0YA 2JBRA 2C0UA 2ZDXA 4KTOA 3KMLA 4FZ4A 1R3BA 3GQTA 1IVHA 1JQIA 2BTZA 2FP2A 4HR3A 1FS8A 1IS2A 3X29A 3CRKA 4AKHA 3FO3A 3S7WA 2EBAA 2C12A 4KSAA 4E02A 2CJ6A 2AZEA 4RM7A 3D9EA 4DOYA 3EONA 3TZ0A 2PG0A 3C2PA 3C46A 1EGCA 3U33A 3CRLA 2EC5A 4L3YA 2OR0A 2VF1A 4H81A 1PI1A 3MXLA 3TORA 2WBIA 2DDHA 4U83A 4FF3A 2BU5A 3TZ5A 2AO2A 2E81A 2RFQA 3Q0AA 1K90A 2REHA 4H7QA 4FF1A 3RKHA 3F29A 3EOMA 4E01A 2R05A 3OWAA 5J6AA 4X28C 3SXQA 4MPCA 5M4PA 1X90A 1X91A 5BRMA 3VKGA 4KS9A 4FF4A 1GKXA 1EGEA 3MDEA 2OEVA 2ZKJA 4WJYA 2CJ8A 4XVXA 2JBSA 1SK6A 4LQSB 3AFEA 2R02A 2CX9A 3GM6A 4N5FA 2CJ7A 2E0AA 2R03A 2F6LA 3BNHA 4W9UA 4Q5BA 2Q8HA 1T9GA 3VKHA 3Q22A 3D1IA 3N0RA 4L1FA 2ZO5A 1OAHA 4JIOA 2JIFA 2R0MA 1S26A 2RF7A 3OWMA 4NXLA 3TZ2A 3TTBA 2R0NA 4IV6A 1XFUA 4FF2A 4Q17A 1EGDA 4M9AA 4ZXVA 3BNJA 3FCJA 2OJQA 3BNFA 3Q24A 3D9DA 3SCEA 1U8VA 2FONA 2LFWA 2YYJA 3D2RA 5B5VA 2Q8GA 3D9FA 3MPJA 1BUCA 3GNCA 1XG2B 1XFYA 2BU2A 2YYLA 5B6BA 4AKGA 2Z1QA 4QICA 1FS9A 1Y0VA 2FP1A 4H85A 4KSFA 5K3HA 5M4KA 3B96A 1XFWA 1Y8NA 4L3ZA 2Q8IA 2XS8A 3SWOA 1W07A 1RX0A 4KCFA 2BU6A 1PK0A 2OEXA 4JIZA 2BU8A 2D29A 3C3LA 2YYGA 3AFFA 5K3JA 4MP2A 3CE2A 5GJVE 2OT4A 3II9A 5K3IA 2IX6A 2XQRB 4E00A 3MMOA 4F0XA 3UU9A 1JM6A 2BU7A 2YYKA 3HWCA 4J1VA 4JEKA 4ZYJA 5BRKA 2A1TA 1GKZA 2E80A 3MPIA 1GJVA 4P13A 1K93A 2XS1A 2ZAFA 2EBFX 5M4MA 2EBHX 4Q1OA 2PNRA 1UKWA 4Q0TA 3UBRA 3Q23A 4MP7A 2DVLA 2JBTA 2J7AA 2ZDYA 5J71A 5EZ3A 1Y8PA 2HJNA 2CJ5A 3PFDA 4L38A 1GU6A 1QDBA 2UXWA 3SF6A 4G97A 4DZYA 1WS9A 1FS7A 2IX5A 2YYMA 2GBBA 3TZ4A 3R7KA 3P4TA 3D9GA 4HKSA 1XFVA 2PO4A 4V26A 4O5MA 4X28A 3LGQA 4MPNA 5M4NA 1XFXA 3DJLA 4MPEA 2VR0A 5B5WA 3BNGA 3MDDA 4Q5CA 3X0XA 3D6BA 1X8ZA 1SIQA 4IRNA 4HKRA 2YGWA 5GJWE 4V25A 3M9VA 3LG1A 4AKIA 3MKHA 4LQQB 1XFZA 1R2JA 1LVCA 1RP3A 2CJ4A 2QR4A 3OIBA 1UDYA 4L3XA 4AI6A 1RJ1A 4Q4UA 1RJ4A 1SIRA
chains in the Genus database with same CATH topology
5K3GA 3NF4A 4G5EA 3L1TA 4OO2A 2VIGA 2RDZA 2YYIA 3X0YA 2JBRA 2C0UA 4KTOA 3GQTA 1IVHA 1JQIA 4HR3A 1FS8A 1IS2A 3FO3A 2EBAA 2C12A 4RM7A 3D9EA 4DOYA 3EONA 2PG0A 1EGCA 4L3YA 2OR0A 3TORA 3MXLA 2WBIA 2DDHA 4U83A 2E81A 2RFQA 2REHA 3RKHA 3F29A 3EOMA 3OWAA 4X28C 3SXQA 1EGEA 3MDEA 4WJYA 4XVXA 2JBSA 3AFEA 2CX9A 3GM6A 4N5FA 3BNHA 4W9UA 4Q5BA 1T9GA 3D1IA 4L1FA 2ZO5A 1OAHA 2JIFA 2R0MA 2RF7A 3OWMA 4NXLA 3TTBA 2R0NA 4IV6A 4Q17A 1EGDA 4M9AA 4ZXVA 3BNJA 3FCJA 3BNFA 3D9DA 3SCEA 1U8VA 2FONA 2YYJA 3S7WA 3D9FA 3MPJA 1BUCA 3GNCA 2YYLA 2Z1QA 1FS9A 5K3HA 3B96A 4L3ZA 3SWOA 1W07A 1RX0A 4KCFA 2D29A 2YYGA 3AFFA 5K3JA 2OT4A 3II9A 5K3IA 2IX6A 3MMOA 3UU9A 2YYKA 3HWCA 4JEKA 4ZYJA 2A1TA 2E80A 3MPIA 4P13A 2ZAFA 3UBRA 4Q1OA 4Q0TA 1UKWA 2DVLA 2JBTA 2J7AA 3PFDA 4L38A 1GU6A 1QDBA 2UXWA 3SF6A 1WS9A 1FS7A 2IX5A 3R7KA 3P4TA 3D9GA 4O5MA 4X28A 3LGQA 2VR0A 3BNGA 3MDDA 4Q5CA 3X0XA 3D6BA 1SIQA 4IRNA 3M9VA 3LG1A 3MKHA 1R2JA 3OIBA 1UDYA 4L3XA 4Q4UA 2YYMA 1SIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5K3G A;  3NF4 A;  4G5E A;  3L1T A;  4OO2 A;  2VIG A;  2RDZ A;  2YYI A;  3X0Y A;  2JBR A;  2C0U A;  4KTO A;  3GQT A;  1IVH A;  1JQI A;  4HR3 A;  1FS8 A;  1IS2 A;  3FO3 A;  2EBA A;  2C12 A;  4RM7 A;  3D9E A;  4DOY A;  3EON A;  2PG0 A;  1EGC A;  4L3Y A;  2OR0 A;  3TOR A;  3MXL A;  2WBI A;  2DDH A;  4U83 A;  2E81 A;  2RFQ A;  2REH A;  3RKH A;  3F29 A;  3EOM A;  3OWA A;  4X28 C;  3SXQ A;  1EGE A;  3MDE A;  4WJY A;  4XVX A;  2JBS A;  3AFE A;  2CX9 A;  3GM6 A;  4N5F A;  3BNH A;  4W9U A;  4Q5B A;  1T9G A;  3D1I A;  4L1F A;  2ZO5 A;  1OAH A;  2JIF A;  2R0M A;  2RF7 A;  3OWM A;  4NXL A;  3TTB A;  2R0N A;  4IV6 A;  4Q17 A;  1EGD A;  4M9A A;  4ZXV A;  3BNJ A;  3FCJ A;  3BNF A;  3D9D A;  3SCE A;  1U8V A;  2FON A;  2YYJ A;  3S7W A;  3D9F A;  3MPJ A;  1BUC A;  3GNC A;  2YYL A;  2Z1Q A;  1FS9 A;  5K3H A;  3B96 A;  4L3Z A;  3SWO A;  1W07 A;  1RX0 A;  4KCF A;  2D29 A;  2YYG A;  3AFF A;  5K3J A;  2OT4 A;  3II9 A;  5K3I A;  2IX6 A;  3MMO A;  3UU9 A;  2YYK A;  3HWC A;  4JEK A;  4ZYJ A;  2A1T A;  2E80 A;  3MPI A;  4P13 A;  2ZAF A;  3UBR A;  4Q1O A;  4Q0T A;  1UKW A;  2DVL A;  2JBT A;  2J7A A;  3PFD A;  4L38 A;  1GU6 A;  1QDB A;  2UXW A;  3SF6 A;  1WS9 A;  1FS7 A;  2IX5 A;  3R7K A;  3P4T A;  3D9G A;  4O5M A;  4X28 A;  3LGQ A;  2VR0 A;  3BNG A;  3MDD A;  4Q5C A;  3X0X A;  3D6B A;  1SIQ A;  4IRN A;  3M9V A;  3LG1 A;  3MKH A;  1R2J A;  3OIB A;  1UDY A;  4L3X A;  4Q4U A;  2YYM A;  1SIR A; 
#chains in the Genus database with same CATH topology
 5K3G A;  3NF4 A;  2Q8F A;  4P79 A;  4G5E A;  3L1T A;  1Y8O A;  4OO2 A;  3VAD A;  2VIG A;  1K8T A;  1SC5 A;  2RDZ A;  2YYI A;  3X0Y A;  2JBR A;  2C0U A;  2ZDX A;  4KTO A;  3KML A;  4FZ4 A;  1R3B A;  3GQT A;  1IVH A;  1JQI A;  2BTZ A;  2FP2 A;  4HR3 A;  1FS8 A;  1IS2 A;  3X29 A;  3CRK A;  4AKH A;  3FO3 A;  3S7W A;  2EBA A;  2C12 A;  4KSA A;  4E02 A;  2CJ6 A;  2AZE A;  4RM7 A;  3D9E A;  4DOY A;  3EON A;  3TZ0 A;  2PG0 A;  3C2P A;  3C46 A;  1EGC A;  3U33 A;  3CRL A;  2EC5 A;  4L3Y A;  2OR0 A;  2VF1 A;  4H81 A;  1PI1 A;  3MXL A;  3TOR A;  2WBI A;  2DDH A;  4U83 A;  4FF3 A;  2BU5 A;  3TZ5 A;  2AO2 A;  2E81 A;  2RFQ A;  3Q0A A;  1K90 A;  2REH A;  4H7Q A;  4FF1 A;  3RKH A;  3F29 A;  3EOM A;  4E01 A;  2R05 A;  3OWA A;  5J6A A;  4X28 C;  3SXQ A;  4MPC A;  5M4P A;  1X90 A;  1X91 A;  5BRM A;  3VKG A;  4KS9 A;  4FF4 A;  1GKX A;  1EGE A;  3MDE A;  2OEV A;  2ZKJ A;  4WJY A;  2CJ8 A;  4XVX A;  2JBS A;  1SK6 A;  4LQS B;  3AFE A;  2R02 A;  2CX9 A;  3GM6 A;  4N5F A;  2CJ7 A;  2E0A A;  2R03 A;  2F6L A;  3BNH A;  4W9U A;  4Q5B A;  2Q8H A;  1T9G A;  3VKH A;  3Q22 A;  3D1I A;  3N0R A;  4L1F A;  2ZO5 A;  1OAH A;  4JIO A;  2JIF A;  2R0M A;  1S26 A;  2RF7 A;  3OWM A;  4NXL A;  3TZ2 A;  3TTB A;  2R0N A;  4IV6 A;  1XFU A;  4FF2 A;  4Q17 A;  1EGD A;  4M9A A;  4ZXV A;  3BNJ A;  3FCJ A;  2OJQ A;  3BNF A;  3Q24 A;  3D9D A;  3SCE A;  1U8V A;  2FON A;  2LFW A;  2YYJ A;  3D2R A;  5B5V A;  2Q8G A;  3D9F A;  3MPJ A;  1BUC A;  3GNC A;  1XG2 B;  1XFY A;  2BU2 A;  2YYL A;  5B6B A;  4AKG A;  2Z1Q A;  4QIC A;  1FS9 A;  1Y0V A;  2FP1 A;  4H85 A;  4KSF A;  5K3H A;  5M4K A;  3B96 A;  1XFW A;  1Y8N A;  4L3Z A;  2Q8I A;  2XS8 A;  3SWO A;  1W07 A;  1RX0 A;  4KCF A;  2BU6 A;  1PK0 A;  2OEX A;  4JIZ A;  2BU8 A;  2D29 A;  3C3L A;  2YYG A;  3AFF A;  5K3J A;  4MP2 A;  3CE2 A;  5GJV E;  2OT4 A;  3II9 A;  5K3I A;  2IX6 A;  2XQR B;  4E00 A;  3MMO A;  4F0X A;  3UU9 A;  1JM6 A;  2BU7 A;  2YYK A;  3HWC A;  4J1V A;  4JEK A;  4ZYJ A;  5BRK A;  2A1T A;  1GKZ A;  2E80 A;  3MPI A;  1GJV A;  4P13 A;  1K93 A;  2XS1 A;  2ZAF A;  2EBF X;  5M4M A;  2EBH X;  4Q1O A;  2PNR A;  1UKW A;  4Q0T A;  3UBR A;  3Q23 A;  4MP7 A;  2DVL A;  2JBT A;  2J7A A;  2ZDY A;  5J71 A;  5EZ3 A;  1Y8P A;  2HJN A;  2CJ5 A;  3PFD A;  4L38 A;  1GU6 A;  1QDB A;  2UXW A;  3SF6 A;  4G97 A;  4DZY A;  1WS9 A;  1FS7 A;  2IX5 A;  2YYM A;  2GBB A;  3TZ4 A;  3R7K A;  3P4T A;  3D9G A;  4HKS A;  1XFV A;  2PO4 A;  4V26 A;  4O5M A;  4X28 A;  3LGQ A;  4MPN A;  5M4N A;  1XFX A;  3DJL A;  4MPE A;  2VR0 A;  5B5W A;  3BNG A;  3MDD A;  4Q5C A;  3X0X A;  3D6B A;  1X8Z A;  1SIQ A;  4IRN A;  4HKR A;  2YGW A;  5GJW E;  4V25 A;  3M9V A;  3LG1 A;  4AKI A;  3MKH A;  4LQQ B;  1XFZ A;  1R2J A;  1LVC A;  1RP3 A;  2CJ4 A;  2QR4 A;  3OIB A;  1UDY A;  4L3X A;  4AI6 A;  1RJ1 A;  4Q4U A;  1RJ4 A;  1SIR A; 
#chains in the Genus database with same CATH homology
 5K3G A;  3NF4 A;  4G5E A;  3L1T A;  4OO2 A;  2VIG A;  2RDZ A;  2YYI A;  3X0Y A;  2JBR A;  2C0U A;  4KTO A;  3GQT A;  1IVH A;  1JQI A;  4HR3 A;  1FS8 A;  1IS2 A;  3FO3 A;  2EBA A;  2C12 A;  4RM7 A;  3D9E A;  4DOY A;  3EON A;  2PG0 A;  1EGC A;  4L3Y A;  2OR0 A;  3TOR A;  3MXL A;  2WBI A;  2DDH A;  4U83 A;  2E81 A;  2RFQ A;  2REH A;  3RKH A;  3F29 A;  3EOM A;  3OWA A;  4X28 C;  3SXQ A;  1EGE A;  3MDE A;  4WJY A;  4XVX A;  2JBS A;  3AFE A;  2CX9 A;  3GM6 A;  4N5F A;  3BNH A;  4W9U A;  4Q5B A;  1T9G A;  3D1I A;  4L1F A;  2ZO5 A;  1OAH A;  2JIF A;  2R0M A;  2RF7 A;  3OWM A;  4NXL A;  3TTB A;  2R0N A;  4IV6 A;  4Q17 A;  1EGD A;  4M9A A;  4ZXV A;  3BNJ A;  3FCJ A;  3BNF A;  3D9D A;  3SCE A;  1U8V A;  2FON A;  2YYJ A;  3S7W A;  3D9F A;  3MPJ A;  1BUC A;  3GNC A;  2YYL A;  2Z1Q A;  1FS9 A;  5K3H A;  3B96 A;  4L3Z A;  3SWO A;  1W07 A;  1RX0 A;  4KCF A;  2D29 A;  2YYG A;  3AFF A;  5K3J A;  2OT4 A;  3II9 A;  5K3I A;  2IX6 A;  3MMO A;  3UU9 A;  2YYK A;  3HWC A;  4JEK A;  4ZYJ A;  2A1T A;  2E80 A;  3MPI A;  4P13 A;  2ZAF A;  3UBR A;  4Q1O A;  4Q0T A;  1UKW A;  2DVL A;  2JBT A;  2J7A A;  3PFD A;  4L38 A;  1GU6 A;  1QDB A;  2UXW A;  3SF6 A;  1WS9 A;  1FS7 A;  2IX5 A;  3R7K A;  3P4T A;  3D9G A;  4O5M A;  4X28 A;  3LGQ A;  2VR0 A;  3BNG A;  3MDD A;  4Q5C A;  3X0X A;  3D6B A;  1SIQ A;  4IRN A;  3M9V A;  3LG1 A;  3MKH A;  1R2J A;  3OIB A;  1UDY A;  4L3X A;  4Q4U A;  2YYM A;  1SIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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