The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
97
|
sequence length |
394
|
structure length |
376
|
Chain Sequence |
LDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHECKIAPTKNEQQLFYISQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMHKIPLHTVRQFFMEDIVLANHPDIFNPDNPKVTQAIQSFCLEKIEEMLENAERERLGNSHQPEKPLVRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDIIHFFR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Hydrolase
|
| molecule keywords |
Double-strand break repair protein MRE11A
|
| publication title |
Crystal structure of human mre11: understanding tumorigenic mutations
pubmed doi rcsb |
| source organism |
Homo sapiens
|
| total genus |
97
|
| structure length |
376
|
| sequence length |
394
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature | |
| pdb deposition date | 2011-07-22 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00149 | Metallophos | Calcineurin-like phosphoesterase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Translation Initiation Factor IF3 | Translation Initiation Factor IF3 | ||
| Alpha Beta | 4-Layer Sandwich | Purple Acid Phosphatase; chain A, domain 2 | Purple Acid Phosphatase; chain A, domain 2 |
#chains in the Genus database with same CATH superfamily 3K7W C; 1S70 A; 1IT6 A; 4UT3 A; 4I5N C; 3IVD A; 2WDD A; 1V73 A; 4O24 A; 3K7V C; 5IOH A; 2HYP A; 4DSY A; 3AV0 A; 4Q7F A; 4TUG A; 4KBP A; 1WAR A; 3H68 A; 1XM7 A; 3CK2 A; 3T1I A; 3THN A; 1KBP A; 3IVE A; 3H63 A; 2Z1A A; 1MF8 A; 5INB A; 2WDC A; 4V0X A; 3RL4 A; 4M0V A; 2QJC A; 2IE3 C; 4IL1 A; 2O8A A; 4ZX2 A; 3RL5 A; 1NNW A; 1JK7 A; 4HD0 A; 4IYP C; 1W24 A; 3RL3 A; 5EQV A; 1S3L A; 1UF3 A; 5JJT A; 4XPN A; 4G9J A; 1USH A; 2WDE A; 2CV9 A; 4LAC C; 4I5L C; 4H1Y P; 2GJU A; 2QFR A; 1T71 A; 4DT2 A; 3TGH A; 3ICF A; 2HYO A; 3DW8 C; 4OR9 A; 4MOV A; 1QHW A; 4H2I A; 1UTE A; 4ZVZ A; 3PSO A; 2BDX A; 3ZU0 A; 4TUI A; 4NZV A; 4ORC A; 1WAO 1; 4JA9 A; 3KBP A; 4UT2 A; 2BCD A; 1U32 A; 5DNY A; 3C5W C; 2O8G A; 1SU1 A; 2QFP A; 2WDF A; 1HO5 A; 2JOG A; 4MP0 A; 4F0Z A; 4O43 A; 1G5B A; 4O5G A; 4UWQ A; 3HVQ A; 1II7 A; 4B2O A; 1HPU A; 4KKZ A; 4UT3 B; 3C9F A; 4FBW A; 1S3M A; 2NYM C; 3N5U A; 3THO B; 5HPE A; 4WWL A; 5JPE A; 1QFC A; 4FBK A; 3H69 A; 5GTU A; 3E7A A; 1FJM A; 3QFK A; 5J28 A; 2R17 A; 3QG5 C; 4ORB A; 1Z2W A; 2Z06 A; 2NPP C; 4DHL A; 5B8I A; 1Z2X A; 5C1V A; 4LU9 A; 2P6B A; 2AHD A; 2NXF A; 1OI8 A; 3EGH A; 1OID A; 1OIE A; 3H62 B; 3QFN A; 3ZTV A; 1XZW A; 3GVE A; 3DSC A; 3EGG A; 3H60 A; 2XMO A; 3LL8 A; 4FCX A; 1S8E A; 2NYL C; 2IAE C; 3H61 A; 2A22 A; 2Q8U A; 3AUZ A; 2Z72 A; 3H67 A; 3IB8 A; 3QFM A; 3FGA C; 1AUI A; 1HP1 A; 2YVT A; 3DSD A; 1M63 A; 4YKE A; 3H64 A; 4H2F A; 3RQZ A; 4FBQ A; 1S95 A; 4LTY A; 2BQ8 X; 1T70 A; 3H66 A; 1TCO A; 3JYF A; 3QFO A; 4ORA A; 3IB7 A; 4J6O A; 4H2G A; 4H2B A; 2IE4 C; 1S3N A; 2ZBM A; 3PSN A; 4MOY A; 3E7B A; 5JPF A; 5F3W A; 2DFJ A; 4V0V A; 4JA7 A; 3V4Y A; 2HY1 A; 4H1S A; 3P71 C; 2USH A; 2KKN A; 4V0W A; 4O4K A; #chains in the Genus database with same CATH topology 3K7W C; 4Q15 A; 3TOE A; 1S70 A; 1IT6 A; 4UT3 A; 4I5N C; 3IVD A; 2WDD A; 1V73 A; 4O24 A; 3K7V C; 5IOH A; 2HYP A; 4DSY A; 3AV0 A; 4Q7F A; 3TTF A; 4KBP A; 4TUG A; 3LVJ C; 1WAR A; 1LN4 A; 3H68 A; 1XM7 A; 3CK2 A; 3T1I A; 3THN A; 2YEQ A; 3QKB A; 1KBP A; 3IVE A; 3LVK B; 3H63 A; 1TIG A; 1H4T A; 2Z1A A; 1MF8 A; 3TSP A; 5INB A; 2WDC A; 1VM0 A; 4V0X A; 3RL4 A; 3IAB A; 4M0V A; 2QJC A; 2ZO9 B; 2IE3 C; 4IL1 A; 2O8A A; 4ZX2 A; 3RL5 A; 1NNW A; 1JK7 A; 4HD0 A; 4DT2 A; 2Y1B A; 2A2Y A; 2ZOA A; 4IYP C; 1W24 A; 3RL3 A; 5EQV A; 3D03 A; 4TWA A; 1S3L A; 1UF3 A; 2BKY X; 5JJT A; 3ZIG A; 2CRQ A; 4XPN A; 4G9J A; 4NCX A; 1USH A; 2WDE A; 2CV9 A; 4LAC C; 4I5L C; 4H1Y P; 2GJU A; 2QFR A; 3VTI A; 4OLF A; 1T71 A; 2GTC A; 2HYO A; 2Q3V A; 3DW8 C; 3ICF A; 1NH9 A; 4MOV A; 3U6Y A; 4OR9 A; 1H0X A; 1QHW A; 4K87 A; 1UTE A; 4H2I A; 4ZVZ A; 3PSO A; 2BDX A; 3ZU0 A; 4HVC A; 4TUI A; 1NFH A; 4NZV A; 2DXN A; 1WAO 1; 4ORC A; 4JA9 A; 3KBP A; 4UT2 A; 2BCD A; 1NJ2 A; 1U32 A; 1NFJ A; 5DNY A; 1Y2I A; 1JE3 A; 2O8G A; 3C5W C; 1XEZ A; 4K88 A; 4YDQ A; 1NJ6 A; 2DXL A; 1SU1 A; 2P9B A; 2QFP A; 2WDF A; 1HO5 A; 2JOG A; 4MP0 A; 4NZT M; 4F0Z A; 1Y9X A; 4O43 A; 1G5B A; 4O5G A; 4UWQ A; 3HVQ A; 1II7 A; 2EK0 A; 3P04 A; 4EO0 A; 4B2O A; 1HPU A; 4KKZ A; 4UT3 B; 3C9F A; 4FBW A; 1S3M A; 1H0Y A; 2NYM C; 3N5U A; 3THO B; 5HPE A; 4WWL A; 5JPE A; 1QFC A; 4FBK A; 2LN3 A; 3H69 A; 5GTU A; 3E7A A; 3TGH A; 1FJM A; 3QFK A; 2IFE A; 5J28 A; 2R17 A; 3QG5 C; 4ORB A; 1Z2W A; 2Z06 A; 2NPP C; 4DHL A; 5B8I A; 1Z2X A; 5C1V A; 1RQ8 A; 4LU9 A; 1NJ8 A; 2P6B A; 1H4Q A; 2LXR A; 3TTD A; 2AHD A; 2L8Y A; 2NXF A; 1VR4 A; 1NJ1 A; 1OI8 A; 3EGH A; 3FLO A; 1OID A; 1OIE A; 3TTC A; 4NZR M; 3IAB B; 3H62 B; 3QFN A; 3ZTV A; 1XZW A; 3GVE A; 3DSC A; 3EGG A; 1NJ5 A; 4HVZ A; 1JO0 A; 3H60 A; 2XMO A; 3LL8 A; 4FCX A; 1S8E A; 3ZIH A; 2IAE C; 2H9U A; 2NYL C; 3H61 A; 3IAL A; 3HZ7 A; 2A22 A; 2Q8U A; 3WBM A; 3AUZ A; 2Z72 A; 3E0J A; 3H67 A; 3IB8 A; 3QFM A; 3FGA C; 2M71 A; 4K86 A; 1AUI A; 1HP1 A; 2YVT A; 3VTH A; 3DSD A; 1M63 A; 4YKE A; 3H64 A; 4H2F A; 3ZII A; 3RQZ A; 4Z9E A; 4FBQ A; 1S95 A; 4LTY A; 2BQ8 X; 1UDV A; 1T70 A; 3H66 A; 1TCO A; 3JYF A; 3QFO A; 4ORA A; 3IB7 A; 4J6O A; 4WI1 A; 4H2G A; 4H2B A; 2IE4 C; 1S3N A; 2ZBM A; 2Z7C A; 3TSU A; 3PSN A; 4MOY A; 3E7B A; 5JPF A; 5F3W A; 1DCJ A; 3TSQ A; 3ZIE A; 2DFJ A; 4V0V A; 4JA7 A; 3V4Y A; 2HY1 A; 4H1S A; 1HC7 A; 3P71 C; 1H4S A; 2USH A; 1JDQ A; 2KKN A; 1PAV A; 2EH1 A; 4V0W A; 4O4K A; #chains in the Genus database with same CATH homology 3K7W C; 1S70 A; 1IT6 A; 4UT3 A; 4I5N C; 3IVD A; 2WDD A; 1V73 A; 4O24 A; 3K7V C; 5IOH A; 2HYP A; 4DSY A; 3AV0 A; 4Q7F A; 3TTF A; 4KBP A; 4TUG A; 1WAR A; 3H68 A; 1XM7 A; 3CK2 A; 3T1I A; 3THN A; 2YEQ A; 1KBP A; 3IVE A; 3H63 A; 2Z1A A; 1MF8 A; 3TSP A; 5INB A; 2WDC A; 4V0X A; 3RL4 A; 4M0V A; 2QJC A; 2ZO9 B; 2IE3 C; 4IL1 A; 2O8A A; 4ZX2 A; 3RL5 A; 1NNW A; 1JK7 A; 4HD0 A; 2ZOA A; 4IYP C; 1W24 A; 3RL3 A; 5EQV A; 3D03 A; 1S3L A; 1UF3 A; 5JJT A; 3ZIG A; 4XPN A; 4G9J A; 1USH A; 2WDE A; 2CV9 A; 4LAC C; 4I5L C; 4H1Y P; 2GJU A; 2QFR A; 3VTI A; 1T71 A; 3TGH A; 3ICF A; 2HYO A; 3DW8 C; 4DT2 A; 4OR9 A; 4MOV A; 1QHW A; 4H2I A; 1UTE A; 4ZVZ A; 3PSO A; 2BDX A; 3ZU0 A; 4TUI A; 4NZV A; 2DXN A; 1WAO 1; 4ORC A; 4JA9 A; 3KBP A; 4UT2 A; 2BCD A; 1U32 A; 5DNY A; 3C5W C; 2O8G A; 1XEZ A; 2DXL A; 1SU1 A; 2P9B A; 2QFP A; 2WDF A; 1HO5 A; 2JOG A; 4MP0 A; 4NZT M; 4F0Z A; 4O43 A; 1G5B A; 4O5G A; 4UWQ A; 3HVQ A; 1II7 A; 3P04 A; 4EO0 A; 4B2O A; 1HPU A; 4KKZ A; 4UT3 B; 3C9F A; 4FBW A; 1S3M A; 2NYM C; 3N5U A; 3THO B; 5HPE A; 4WWL A; 5JPE A; 1QFC A; 4FBK A; 2LN3 A; 3H69 A; 5GTU A; 3E7A A; 1FJM A; 3QFK A; 5J28 A; 2R17 A; 3QG5 C; 4ORB A; 1Z2W A; 2Z06 A; 2NPP C; 4DHL A; 5B8I A; 1Z2X A; 5C1V A; 4LU9 A; 2P6B A; 2AHD A; 3TTD A; 2NXF A; 1OI8 A; 3EGH A; 3FLO A; 1OID A; 1OIE A; 3TTC A; 4NZR M; 3H62 B; 3QFN A; 3ZTV A; 1XZW A; 3GVE A; 3DSC A; 3EGG A; 4HVZ A; 3H60 A; 2XMO A; 3LL8 A; 4FCX A; 3ZIH A; 1S8E A; 2IAE C; 2NYL C; 3H61 A; 2A22 A; 2Q8U A; 3AUZ A; 2Z72 A; 3E0J A; 3H67 A; 3IB8 A; 3QFM A; 3FGA C; 1AUI A; 1HP1 A; 2YVT A; 3VTH A; 3DSD A; 1M63 A; 4YKE A; 3H64 A; 4H2F A; 3ZII A; 3RQZ A; 4FBQ A; 1S95 A; 4LTY A; 2BQ8 X; 1T70 A; 3H66 A; 1TCO A; 3JYF A; 3QFO A; 4ORA A; 3IB7 A; 4J6O A; 4H2G A; 4H2B A; 2IE4 C; 1S3N A; 2ZBM A; 3TSU A; 3PSN A; 4MOY A; 3E7B A; 5JPF A; 5F3W A; 3TSQ A; 3ZIE A; 2DFJ A; 4V0V A; 4JA7 A; 3V4Y A; 2HY1 A; 4H1S A; 3P71 C; 2USH A; 2KKN A; 4V0W A; 4O4K A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
