3UGDA

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase c delta
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
65
structure length
65
Chain Sequence
GSRRASVGSHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCEFIVTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
pubmed doi rcsb
molecule tags Metal binding protein
source organism Mus musculus
molecule keywords Protein kinase C delta type
total genus 10
structure length 65
sequence length 65
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-11-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3ugdA01
3UEJA 2B8TA 3UGIA 5FUXA 1XBTA 3UGDA 1KBEA 4L9MA 3BJIA 5FUVA 1PTRA 2JA1A 3UEYA 2E73A 2ENNA 3KY9A 2GVIA 2QQEA 2ORVA 1XA6A 1Y8FA 1W4RA 2QQ0A 2YUUA 3CXLA 2ELIA 2QPOA 5FUYA 2UZ3A 1TBOA 1PTQA 1R79A 2FNFX 3UFFA 4UXIA 1RFHA 4FKDA 2ROWA 3UGLA 2WVJA 4UXJA 1KBFA 1FARA 4B6DA 2DB6A 4UXHA 5FUWA 1TBNA 3E2IA 2ORWA 2VRWB 1FAQA 2J9RA 2J87A 1XX6A 2ENZA
chains in the Genus database with same CATH superfamily
1WGTA 1TBQR 1IW4A 1TURA 2B8TA 1TUSA 1XBTA 3FSYA 2LUYA 1MJBA 2GIVA 1KBEA 1CGJI 1CGII 1SGQI 4HGUA 1DS2I 1W3SA 1SGPI 4MPIA 5J8CA 1HEVA 2B0UC 2F3CI 3BJIA 1DS3I 2SGQI 2QQDA 3E59A 3HH2C 5HI7A 1UVGA 3UEYA 3VDPA 2E73A 1WGCA 2ODDA 2W0TA 2XRCA 5DAEA 5J8FA 1X4SA 2QQEA 1H0ZA 1OMTA 1PPFI 4OVOA 3R5AA 2KCXA 2X3TA 1LR7A 2YUUA 2ELIA 2QPOA 2SGFI 5FUYA 2FNFX 1LR8A 3PDNA 2NU4I 1RFHA 4FKDA 2OVOA 3UGLA 2NU1I 1MJ9A 2K9HA 1OYVI 1BUSA 1NXUA 2DB6A 1X74A 2V1CC 4UXHA 4B6DA 2ORWA 2V1CA 1Q9BA 2N1AB 3R5BA 4WP4A 1SGYI 2J87A 1ULMA 2DKVA 2NU2I 3OXLA 1FYBA 1YU6C 2DIPA 5E3QA 1P9GA 3UEJA 1YTPA 3UGIA 2Y0MA 1ULNA 1NUBA 2KMRA 1CHOI 1K7VA 1PCEA 3TOBA 1MT1A 2LEOA 3B4VC 5FUVA 1CT4I 4SGBI 3TO9A 2N17A 5EX0A 2OU2A 3SEKC 1CE3A 2NU3I 1UUCA 1TIHA 3OXFA 5E3RA 5JHWC 2KMOA 1W4RA 1Y8FA 1M8CA 2CWHA 2QQ0A 1CT0I 1CSOI 2NU0I 5CCLA 1UHAA 1TBOA 2SGDI 1R79A 3OL0A 3UFFA 2WCYA 1K7TA 4UXIA 1M8BA 2ROWA 2A20A 4UXJA 1KBFA 1Z2IA 5CCMA 3MEKA 2JYYA 3QAHA 2RC4A 4AMLA 3GOXA 3E2IA 1SGNI 2X52A 2J9RA 1WTJA 2PQ8A 2UVOA 3SGQI 1IY6A 1N13A 1K7UA 4GI3C 2E5RA 5E3PA 5HQ8A 1TOTA 2YQPA 3TOAA 1AN1I 1S20A 1V1HA 1TBRR 1TGSI 1Y1CA 1LR9A 1MJAA 1PTRA 2JA1A 2QQCA 2BUSA 7WGAA 2ENNA 3KY9A 1SGDI 2GVIA 2GKRI 1Z7KB 2M5XA 3TO6A 2GKVA 1KMAA 1XA6A 2ERWA 9WGAA 1HJAI 1PTQA 2JW6A 3VDUA 3R5CA 4E1RA 1FARA 2ARPF 1BMOA 1TBNA 2WGCA 3QTLD 3FSXA 1FAQA 1HPTA 2OD1A 2RIJA 1XX6A 2ENZA 1WKXA 3UGDA 1FY7A 1R0RI 3FC3A 2GKTI 5EX3A 1V1IA 5FUXA 3RU0A 4A24A 2L7XA 2CWGA 4E1PA 2P6AC 3SGBI 2CJSC 4L9MA 2L8EA 1PJUA 2JXDA 2KMPA 2LB7A 2OZUA 3TO7A 1OMUA 3VE5A 1ULKA 1OVOA 2JZMA 3UOEA 2KMQA 3D00A 2ORVA 1P9ZA 1UVFA 1IY5A 3CXLA 2UZ3A 3OXGA 2SGEI 3R5DA 1SGEI 1U5KA 2N52A 2WVJA 4JCVE 3QWPA 1CT2I 1VDDA 3TJQA 1HDLA 5FUWA 2N71A 2SGPI 2V53A 2VRWB 3OVOA 2CWFA 1Y1BA 4DNCA 1SGRI
chains in the Genus database with same CATH topology
1TBQR 1IW4A 1TURA 2B8TA 1TUSA 1XBTA 2LUYA 1KBEA 1CGJI 1CGII 1SGQI 4HGUA 1DS2I 1W3SA 1SGPI 2B0UC 2F3CI 3BJIA 1DS3I 2SGQI 2QQDA 3E59A 3HH2C 5HI7A 1UVGA 3UEYA 3VDPA 2E73A 5DAEA 2ODDA 2W0TA 2XRCA 1H0ZA 1X4SA 2QQEA 1OMTA 1PPFI 4OVOA 2KCXA 2YUUA 1LR7A 2ELIA 2QPOA 2SGFI 5FUYA 2FNFX 1LR8A 3PDNA 2NU4I 1RFHA 4FKDA 2OVOA 3UGLA 2NU1I 2K9HA 1OYVI 1BUSA 2V1CC 2DB6A 1X74A 4UXHA 4B6DA 2ORWA 2V1CA 2N1AB 1SGYI 2J87A 3OXLA 1FYBA 2NU2I 1YU6C 2DIPA 3UEJA 1YTPA 3UGIA 1NUBA 2KMRA 1CHOI 1PCEA 1MT1A 2LEOA 3B4VC 5FUVA 1CT4I 4SGBI 2N17A 5EX0A 3SEKC 1CE3A 2NU3I 1UUCA 1TIHA 3OXFA 5JHWC 2KMOA 1W4RA 1Y8FA 1M8CA 2QQ0A 1CT0I 1CSOI 2NU0I 5CCLA 1TBOA 2SGDI 1R79A 3OL0A 3UFFA 2WCYA 4UXIA 1M8BA 2ROWA 2A20A 4UXJA 1KBFA 5CCMA 3MEKA 2JYYA 3GOXA 3E2IA 1SGNI 2J9RA 3SGQI 1IY6A 1N13A 4GI3C 2E5RA 5HQ8A 1TOTA 2YQPA 1AN1I 1V1HA 1TBRR 1TGSI 1Y1CA 1LR9A 1PTRA 2JA1A 2QQCA 2BUSA 2ENNA 3KY9A 1SGDI 2GVIA 2GKRI 1Z7KB 2M5XA 1KMAA 2GKVA 1XA6A 2ERWA 1HJAI 1PTQA 2JW6A 3VDUA 4E1RA 1FARA 2ARPF 1BMOA 1TBNA 3QTLD 1FAQA 1HPTA 2OD1A 1XX6A 2ENZA 3UGDA 1R0RI 3FC3A 2GKTI 5EX3A 1V1IA 5FUXA 3RU0A 4A24A 2L7XA 4E1PA 2P6AC 3SGBI 2CJSC 4L9MA 2L8EA 1PJUA 2JXDA 2KMPA 1OMUA 3VE5A 1OVOA 2JZMA 2KMQA 3D00A 2ORVA 1UVFA 1IY5A 3CXLA 2UZ3A 3OXGA 2SGEI 1SGEI 1U5KA 2N52A 2WVJA 4JCVE 3QWPA 1CT2I 1VDDA 3TJQA 1HDLA 5FUWA 2N71A 2SGPI 2V53A 2VRWB 3OVOA 1Y1BA 1SGRI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UEJ A;  2B8T A;  3UGI A;  5FUX A;  1XBT A;  3UGD A;  1KBE A;  4L9M A;  3BJI A;  5FUV A;  1PTR A;  2JA1 A;  3UEY A;  2E73 A;  2ENN A;  3KY9 A;  2GVI A;  2QQE A;  2ORV A;  1XA6 A;  1Y8F A;  1W4R A;  2QQ0 A;  2YUU A;  3CXL A;  2ELI A;  2QPO A;  5FUY A;  2UZ3 A;  1TBO A;  1PTQ A;  1R79 A;  2FNF X;  3UFF A;  4UXI A;  1RFH A;  4FKD A;  2ROW A;  3UGL A;  2WVJ A;  4UXJ A;  1KBF A;  1FAR A;  4B6D A;  2DB6 A;  4UXH A;  5FUW A;  1TBN A;  3E2I A;  2ORW A;  2VRW B;  1FAQ A;  2J9R A;  2J87 A;  1XX6 A;  2ENZ A; 
#chains in the Genus database with same CATH topology
 1WGT A;  1TBQ R;  1IW4 A;  1TUR A;  2B8T A;  1TUS A;  1XBT A;  3FSY A;  2LUY A;  1MJB A;  2GIV A;  1KBE A;  1CGJ I;  1CGI I;  1SGQ I;  4HGU A;  1DS2 I;  1W3S A;  1SGP I;  4MPI A;  5J8C A;  1HEV A;  2B0U C;  2F3C I;  3BJI A;  1DS3 I;  2SGQ I;  2QQD A;  3E59 A;  3HH2 C;  5HI7 A;  1UVG A;  3UEY A;  3VDP A;  2E73 A;  1WGC A;  2ODD A;  2W0T A;  2XRC A;  5DAE A;  5J8F A;  1X4S A;  2QQE A;  1H0Z A;  1OMT A;  1PPF I;  4OVO A;  3R5A A;  2KCX A;  2X3T A;  1LR7 A;  2YUU A;  2ELI A;  2QPO A;  2SGF I;  5FUY A;  2FNF X;  1LR8 A;  3PDN A;  2NU4 I;  1RFH A;  4FKD A;  2OVO A;  3UGL A;  2NU1 I;  1MJ9 A;  2K9H A;  1OYV I;  1BUS A;  1NXU A;  2DB6 A;  1X74 A;  2V1C C;  4UXH A;  4B6D A;  2ORW A;  2V1C A;  1Q9B A;  2N1A B;  3R5B A;  4WP4 A;  1SGY I;  2J87 A;  1ULM A;  2DKV A;  2NU2 I;  3OXL A;  1FYB A;  1YU6 C;  2DIP A;  5E3Q A;  1P9G A;  3UEJ A;  1YTP A;  3UGI A;  2Y0M A;  1ULN A;  1NUB A;  2KMR A;  1CHO I;  1K7V A;  1PCE A;  3TOB A;  1MT1 A;  2LEO A;  3B4V C;  5FUV A;  1CT4 I;  4SGB I;  3TO9 A;  2N17 A;  5EX0 A;  2OU2 A;  3SEK C;  1CE3 A;  2NU3 I;  1UUC A;  1TIH A;  3OXF A;  5E3R A;  5JHW C;  2KMO A;  1W4R A;  1Y8F A;  1M8C A;  2CWH A;  2QQ0 A;  1CT0 I;  1CSO I;  2NU0 I;  5CCL A;  1UHA A;  1TBO A;  2SGD I;  1R79 A;  3OL0 A;  3UFF A;  2WCY A;  1K7T A;  4UXI A;  1M8B A;  2ROW A;  2A20 A;  4UXJ A;  1KBF A;  1Z2I A;  5CCM A;  3MEK A;  2JYY A;  3QAH A;  2RC4 A;  4AML A;  3GOX A;  3E2I A;  1SGN I;  2X52 A;  2J9R A;  1WTJ A;  2PQ8 A;  2UVO A;  3SGQ I;  1IY6 A;  1N13 A;  1K7U A;  4GI3 C;  2E5R A;  5E3P A;  5HQ8 A;  1TOT A;  2YQP A;  3TOA A;  1AN1 I;  1S20 A;  1V1H A;  1TBR R;  1TGS I;  1Y1C A;  1LR9 A;  1MJA A;  1PTR A;  2JA1 A;  2QQC A;  2BUS A;  7WGA A;  2ENN A;  3KY9 A;  1SGD I;  2GVI A;  2GKR I;  1Z7K B;  2M5X A;  3TO6 A;  2GKV A;  1KMA A;  1XA6 A;  2ERW A;  9WGA A;  1HJA I;  1PTQ A;  2JW6 A;  3VDU A;  3R5C A;  4E1R A;  1FAR A;  2ARP F;  1BMO A;  1TBN A;  2WGC A;  3QTL D;  3FSX A;  1FAQ A;  1HPT A;  2OD1 A;  2RIJ A;  1XX6 A;  2ENZ A;  1WKX A;  3UGD A;  1FY7 A;  1R0R I;  3FC3 A;  2GKT I;  5EX3 A;  1V1I A;  5FUX A;  3RU0 A;  4A24 A;  2L7X A;  2CWG A;  4E1P A;  2P6A C;  3SGB I;  2CJS C;  4L9M A;  2L8E A;  1PJU A;  2JXD A;  2KMP A;  2LB7 A;  2OZU A;  3TO7 A;  1OMU A;  3VE5 A;  1ULK A;  1OVO A;  2JZM A;  3UOE A;  2KMQ A;  3D00 A;  2ORV A;  1P9Z A;  1UVF A;  1IY5 A;  3CXL A;  2UZ3 A;  3OXG A;  2SGE I;  3R5D A;  1SGE I;  1U5K A;  2N52 A;  2WVJ A;  4JCV E;  3QWP A;  1CT2 I;  1VDD A;  3TJQ A;  1HDL A;  5FUW A;  2N71 A;  2SGP I;  2V53 A;  2VRW B;  3OVO A;  2CWF A;  1Y1B A;  4DNC A;  1SGR I; 
#chains in the Genus database with same CATH homology
 1TBQ R;  1IW4 A;  1TUR A;  2B8T A;  1TUS A;  1XBT A;  2LUY A;  1KBE A;  1CGJ I;  1CGI I;  1SGQ I;  4HGU A;  1DS2 I;  1W3S A;  1SGP I;  2B0U C;  2F3C I;  3BJI A;  1DS3 I;  2SGQ I;  2QQD A;  3E59 A;  3HH2 C;  5HI7 A;  1UVG A;  3UEY A;  3VDP A;  2E73 A;  5DAE A;  2ODD A;  2W0T A;  2XRC A;  1H0Z A;  1X4S A;  2QQE A;  1OMT A;  1PPF I;  4OVO A;  2KCX A;  2YUU A;  1LR7 A;  2ELI A;  2QPO A;  2SGF I;  5FUY A;  2FNF X;  1LR8 A;  3PDN A;  2NU4 I;  1RFH A;  4FKD A;  2OVO A;  3UGL A;  2NU1 I;  2K9H A;  1OYV I;  1BUS A;  2V1C C;  2DB6 A;  1X74 A;  4UXH A;  4B6D A;  2ORW A;  2V1C A;  2N1A B;  1SGY I;  2J87 A;  3OXL A;  1FYB A;  2NU2 I;  1YU6 C;  2DIP A;  3UEJ A;  1YTP A;  3UGI A;  1NUB A;  2KMR A;  1CHO I;  1PCE A;  1MT1 A;  2LEO A;  3B4V C;  5FUV A;  1CT4 I;  4SGB I;  2N17 A;  5EX0 A;  3SEK C;  1CE3 A;  2NU3 I;  1UUC A;  1TIH A;  3OXF A;  5JHW C;  2KMO A;  1W4R A;  1Y8F A;  1M8C A;  2QQ0 A;  1CT0 I;  1CSO I;  2NU0 I;  5CCL A;  1TBO A;  2SGD I;  1R79 A;  3OL0 A;  3UFF A;  2WCY A;  4UXI A;  1M8B A;  2ROW A;  2A20 A;  4UXJ A;  1KBF A;  5CCM A;  3MEK A;  2JYY A;  3GOX A;  3E2I A;  1SGN I;  2J9R A;  3SGQ I;  1IY6 A;  1N13 A;  4GI3 C;  2E5R A;  5HQ8 A;  1TOT A;  2YQP A;  1AN1 I;  1V1H A;  1TBR R;  1TGS I;  1Y1C A;  1LR9 A;  1PTR A;  2JA1 A;  2QQC A;  2BUS A;  2ENN A;  3KY9 A;  1SGD I;  2GVI A;  2GKR I;  1Z7K B;  2M5X A;  1KMA A;  2GKV A;  1XA6 A;  2ERW A;  1HJA I;  1PTQ A;  2JW6 A;  3VDU A;  4E1R A;  1FAR A;  2ARP F;  1BMO A;  1TBN A;  3QTL D;  1FAQ A;  1HPT A;  2OD1 A;  1XX6 A;  2ENZ A;  3UGD A;  1R0R I;  3FC3 A;  2GKT I;  5EX3 A;  1V1I A;  5FUX A;  3RU0 A;  4A24 A;  2L7X A;  4E1P A;  2P6A C;  3SGB I;  2CJS C;  4L9M A;  2L8E A;  1PJU A;  2JXD A;  2KMP A;  1OMU A;  3VE5 A;  1OVO A;  2JZM A;  2KMQ A;  3D00 A;  2ORV A;  1UVF A;  1IY5 A;  3CXL A;  2UZ3 A;  3OXG A;  2SGE I;  1SGE I;  1U5K A;  2N52 A;  2WVJ A;  4JCV E;  3QWP A;  1CT2 I;  1VDD A;  3TJQ A;  1HDL A;  5FUW A;  2N71 A;  2SGP I;  2V53 A;  2VRW B;  3OVO A;  1Y1B A;  1SGR I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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