4A1NA

Human mitochondrial endo-exonuclease
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
293
structure length
290
Chain Sequence
KAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGSVLRLEKIMVNLKNEIEPDDYFMSRYEKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human Mitochondrial Endo-Exonuclease
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords NUCLEASE EXOG, MITOCHONDRIAL
total genus 76
structure length 290
sequence length 293
ec nomenclature ec 3.1.30.-:
pdb deposition date 2011-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF18026 Exog_C Endo/exonuclease (EXOG) C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4a1nA01
4ZG7A 4QN0A 5L0BA 2O3BA 2XR9A 3WAXA 1SMNA 5DLTA 3S5BA 2XRGA 1ZM8A 4QGOA 4QH0A 5DLVA 5HRTA 4GTXA 1QAEA 3OWVA 5IJSA 4ZG6A 4GTZA 5KXAA 5LIAA 2XH3A 3ISMA 5IJQA 4GTYA 5GKPA 4GTWA 1G8TA 3NKOA 4ZGAA 1QL0A 3NKRA 4E3YA 5L0KA 5LQQA 5L0EA 4ZG9A 3NKQA 3NKNA 5INHA 3WAWA 3NKPA 3WAYA 3WAVA 3NKMA 4A1NA 2XGRA 5GKCA 4B56A 5DLWA
chains in the Genus database with same CATH superfamily
4ZG7A 4QN0A 5L0BA 2O3BA 2XR9A 3WAXA 1SMNA 5DLTA 3S5BA 2XRGA 1ZM8A 4QGOA 4QH0A 5DLVA 5HRTA 4GTXA 1QAEA 3OWVA 5IJSA 4ZG6A 4GTZA 5KXAA 5LIAA 2XH3A 3ISMA 5IJQA 4GTYA 5GKPA 4GTWA 1G8TA 3NKOA 4ZGAA 1QL0A 3NKRA 4E3YA 5L0KA 5LQQA 5L0EA 4ZG9A 3NKQA 3NKNA 5INHA 3WAWA 3NKPA 3WAYA 3WAVA 3NKMA 4A1NA 2XGRA 5GKCA 4B56A 5DLWA
chains in the Genus database with same CATH topology
4ZG7A 4QN0A 5L0BA 2O3BA 2XR9A 3WAXA 1SMNA 5DLTA 3S5BA 2XRGA 1ZM8A 4QGOA 4QH0A 5DLVA 5HRTA 4GTXA 1QAEA 3OWVA 5IJSA 4ZG6A 4GTZA 5KXAA 5LIAA 2XH3A 3ISMA 5IJQA 4GTYA 5GKPA 4GTWA 1G8TA 3NKOA 4ZGAA 1QL0A 3NKRA 4E3YA 5L0KA 5LQQA 5L0EA 4ZG9A 3NKQA 3NKNA 5INHA 3WAWA 3NKPA 3WAYA 3WAVA 3NKMA 4A1NA 2XGRA 5GKCA 4B56A 5DLWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZG7 A;  4QN0 A;  5L0B A;  2O3B A;  2XR9 A;  3WAX A;  1SMN A;  5DLT A;  3S5B A;  2XRG A;  1ZM8 A;  4QGO A;  4QH0 A;  5DLV A;  5HRT A;  4GTX A;  1QAE A;  3OWV A;  5IJS A;  4ZG6 A;  4GTZ A;  5KXA A;  5LIA A;  2XH3 A;  3ISM A;  5IJQ A;  4GTY A;  5GKP A;  4GTW A;  1G8T A;  3NKO A;  4ZGA A;  1QL0 A;  3NKR A;  4E3Y A;  5L0K A;  5LQQ A;  5L0E A;  4ZG9 A;  3NKQ A;  3NKN A;  5INH A;  3WAW A;  3NKP A;  3WAY A;  3WAV A;  3NKM A;  4A1N A;  2XGR A;  5GKC A;  4B56 A;  5DLW A; 
#chains in the Genus database with same CATH topology
 4ZG7 A;  4QN0 A;  5L0B A;  2O3B A;  2XR9 A;  3WAX A;  1SMN A;  5DLT A;  3S5B A;  2XRG A;  1ZM8 A;  4QGO A;  4QH0 A;  5DLV A;  5HRT A;  4GTX A;  1QAE A;  3OWV A;  5IJS A;  4ZG6 A;  4GTZ A;  5KXA A;  5LIA A;  2XH3 A;  3ISM A;  5IJQ A;  4GTY A;  5GKP A;  4GTW A;  1G8T A;  3NKO A;  4ZGA A;  1QL0 A;  3NKR A;  4E3Y A;  5L0K A;  5LQQ A;  5L0E A;  4ZG9 A;  3NKQ A;  3NKN A;  5INH A;  3WAW A;  3NKP A;  3WAY A;  3WAV A;  3NKM A;  4A1N A;  2XGR A;  5GKC A;  4B56 A;  5DLW A; 
#chains in the Genus database with same CATH homology
 4ZG7 A;  4QN0 A;  5L0B A;  2O3B A;  2XR9 A;  3WAX A;  1SMN A;  5DLT A;  3S5B A;  2XRG A;  1ZM8 A;  4QGO A;  4QH0 A;  5DLV A;  5HRT A;  4GTX A;  1QAE A;  3OWV A;  5IJS A;  4ZG6 A;  4GTZ A;  5KXA A;  5LIA A;  2XH3 A;  3ISM A;  5IJQ A;  4GTY A;  5GKP A;  4GTW A;  1G8T A;  3NKO A;  4ZGA A;  1QL0 A;  3NKR A;  4E3Y A;  5L0K A;  5LQQ A;  5L0E A;  4ZG9 A;  3NKQ A;  3NKN A;  5INH A;  3WAW A;  3NKP A;  3WAY A;  3WAV A;  3NKM A;  4A1N A;  2XGR A;  5GKC A;  4B56 A;  5DLW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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