4A3DL

Rna polymerase ii initial transcribing complex with a 6nt dna-rna hybrid
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
molecule tags Transcription
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3dL00
5FJ8L 3RZDL 5IYDL 5M5WL 4A3DL 3H0GL 4QIWP 4A3EL 1TWHL 3S14L 3PO2L 4A3GL 5M5YL 3HOYL 1R9TL 2NVXL 3HOVL 2NVTL 5IYCL 4AYBP 4C3JL 5IYBL 3HOUL 5M3ML 4A3FL 2E2IL 2NVQL 3I4ML 3S16L 3S1QL 5C3EL 5IP7L 5C44L 1WCML 3GTLL 1TWFL 2Y0SP 3GTQL 1Y1WL 2B63L 1I3QL 3S1RL 2WB1P 4A3LL 4A93L 2YU9L 4C3IL 5M5XL 1TWCL 3CQZL 2WAQP 3S1NL 3HKZP 3GTGL 4A3KL 4Y52L 3I4NL 4X6AL 3S2HL 3HOZL 2NVYL 4BBRL 2E2JL 3S17L 3GTML 2JA8L 4BY7L 3K7AL 1TWAL 5IP9L 4BXXL 4A3ML 3H3VM 2R92L 3GTPL 3FKIL 2JA6L 5M3FL 1I6HL 3M3YL 4A3IL 3PO3L 1I50L 2VUML 4A3BL 4A3CL 4BY1L 3M4OL 3GTOL 3S1ML 1SFOL 4BBSL 2PMZP 4C2M1 2R93L 3RZOL 3HOXL 3S2DL 4C3HL 4Y7NL 1K83L 1TWGL 2JA7L 5FLML 3HOWL 2JA5L 3S15L 1Y1VL 2E2HL 3GTKL 3GTJL 5C4XL 4A3JL 5C4JL 2R7ZL
chains in the Genus database with same CATH superfamily
1IRNA 5FJ8L 3MQKB 2XJQA 3H0GL 1BE7A 4QIWP 1TWHL 7RXNA 2Z3RB 4AHZA 3PO2L 4AR6A 4A3GL 1FHMA 1RDVA 3HOYL 2HR5A 2NVXL 4AR5A 1BRFA 2XJRA 4C3JL 3HOUL 5M3ML 4E6YA 2NVQL 4JAGA 4JADA 3S1QL 5C3EL 1PFWA 1TWFL 3GTQL 3FDJA 2B63L 1R0GA 3S1RL 2WB1P 1QCVA 4YWLA 2NYDA 5M5XL 1TWCL 5AI3A 2RDVA 3LWRB 3SS2A 3HJWB 4A3KL 2PVEA 3I4NL 2PYAA 1YV1A 1VCXA 4XXBB 1VZGA 2E2JL 3S17L 1B2OA 5K2ME 5IP9L 2MS3A 4A3ML 1SMUA 4GS7D 2PPTA 3LPEB 2M6OA 2VUML 2C6BA 3GTOL 1P7PA 2PMZP 4C2M1 5AI2A 4Y7NL 1TWGL 1SMWA 1T9QA 1NXGA 1Y1VL 1R0HA 3GTKL 3PZAA 5C4JL 4AI1A 4G6BA 5IYDL 1BQ9A 5M5WL 3J7Z1 4A3DL 5MFPA 4A3EL 3S14L 3LWQB 1BQ8A 1IU6A 1R9TL 2A6ED 3MSUA 1IROA 2A6HD 1JYBA 1T9PA 1CAAA 2CKAA 5IYBL 3QQCE 1PFYA 2E2IL 2XJPA 4U671 4JAEA 5IP7L 1WCML 1I3QL 4TPUA 2K2DA 5GAHc 5JVH1 5H1Sc 4A3LL 4AI2A 4LHNA 1QYBA 4K9FA 4C3IL 6RXNA 3HAXC 2ERSA 3CQZL 3HKZP 1YK5A 1R0IA 2AQCA 1QQTA 2ERJA 4TVMA 3GTML 2M4YA 2JA8L 1TWAL 5MF6A 4BXXL 2A69D 3PKJA 2R92L 1E8JA 2GMGA 3GTPL 2CKCA 3B08B 1PFUA 3P2AA 4POGA 1OWBA 4A3IL 2XJTA 8RXNA 1I50L 1LTLA 3PL5A 4A3CL 5GADc 3M4OL 4LHLA 3H9CA 4AR4A 2ZIXA 3PKIA 2DSXA 3HOXL 3S2DL 1B71A 1K83L 4JAFA 2JA5L 2PVXA 2KN9A 3VPBE 1WJVA 2CR8A 5C4XL 1LKMA 3IU3I 2R7ZL 1BFYA 3WWNB 3RZDL 4AHXA 3KYVA 5AN9H 3ZG6A 1PFVA 3KYYA 3J7Y1 2B5ID 1DX8A 5DM61 5M5YL 1H7VA 1VZIA 1FHHA 3P8BA 4POFA 5MFZA 4AI3A 4B8CD 4A3FL 3RYGA 2V0EA 1NXEA 3I4ML 1S24A 1F4LA 2JI2A 2JI3A 3PWFA 3S16L 3GTLL 3H97A 2YU9L 3KYUA 3LWPB 3S1NL 2WAQP 1R0FA 2J9UB 1RWDA 4Y52L 4AI0A 2XJSA 3MPSA 4YWMA 1YUZA 1RB9A 5EIOC 3S2HL 3HOZL 2NVYL 5JVG1 2V3BB 4BY7L 4RXNA 3QVDA 2V0FA 3H3VM 2VL6A 2AUSB 2H12A 3FKIL 2JA6L 1IW7D 4A3BL 2A68D 3B0AB 4BY1L 5EINC 2PSMC 2R93L 3RZOL 4V196 1PZXA 1VZHA 2AYJA 1NNQA 2M6PA 2Z3QB 2JA7L 1RYQA 3RZTA 3S15L 2M4VA 2E2HL 5MLC3 3GTJL 1YUXA 1S30A 1R0JA 2KKDA 1DVBA 2RFKB 4AHYA 2C6AA 5IY0A 2BE5D 1OWCA 2LCQA 1ODHA 5MGNA 3K35A 2APOB 3HOVL 3LNLA 2NVTL 5IYCL 5RXNA 4AYBP 1RYTA 3HJYB 4AHWA 1B2JA 2JI1A 2HVYC 2EY4E 2QL0A 5GAGc 5C44L 2Y0SP 1Y1WL 3A44A 1SMMA 3H9BA 5GAEc 4A93L 5DM71 1T9OA 1YK4A 4ME3A 3GTGL 1IU5A 4X6AL 4WFN1 3H99A 4BBRL 3KYXA 4UY81 1CADA 3KYWA 2XJVA 3WWLA 2L0ZA 3LWVB 5M3FL 1I6HL 1C09A 3M3YL 4XGHA 3PO3L 4ZN3B 4AR3A 2XJUA 1B13A 3S1ML 3JR7A 1SFOL 4BBSL 2O5JD 3RZ6A 4C3HL 3PIP1 1LKPA 3HOWL 3NFPI 5FLML 1ZRPA 1LKOA 3PIO1 3LWOB 4ZN1B 1RDGA 1S2ZA 1Z92B 4A3JL 3K7AL
chains in the Genus database with same CATH topology
5FJ8L 3RZDL 5IYDL 5M5WL 4A3DL 3H0GL 4QIWP 4A3EL 1TWHL 3S14L 3PO2L 4A3GL 5M5YL 3HOYL 1R9TL 2NVXL 3HOVL 2NVTL 5IYCL 4AYBP 4C3JL 5IYBL 3HOUL 5M3ML 4A3FL 2E2IL 2NVQL 3I4ML 3S16L 3S1QL 5C3EL 5IP7L 5C44L 1WCML 3GTLL 1TWFL 2Y0SP 3GTQL 1Y1WL 2B63L 1I3QL 3S1RL 2WB1P 4A3LL 4A93L 2YU9L 4C3IL 5M5XL 1TWCL 3CQZL 2WAQP 3S1NL 3HKZP 3GTGL 4A3KL 4Y52L 3I4NL 4X6AL 3S2HL 3HOZL 2NVYL 4BBRL 2E2JL 3S17L 3GTML 2JA8L 4BY7L 3K7AL 1TWAL 5IP9L 4BXXL 4A3ML 3H3VM 2R92L 3GTPL 3FKIL 2JA6L 5M3FL 1I6HL 3M3YL 4A3IL 3PO3L 1I50L 2VUML 4A3BL 4A3CL 4BY1L 3M4OL 3GTOL 3S1ML 1SFOL 4BBSL 2PMZP 4C2M1 2R93L 3RZOL 3HOXL 3S2DL 4C3HL 4Y7NL 1K83L 1TWGL 2JA7L 5FLML 3HOWL 2JA5L 3S15L 1Y1VL 2E2HL 3GTKL 3GTJL 5C4XL 4A3JL 5C4JL 2R7ZL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FJ8 L;  3RZD L;  5IYD L;  5M5W L;  4A3D L;  3H0G L;  4QIW P;  4A3E L;  1TWH L;  3S14 L;  3PO2 L;  4A3G L;  5M5Y L;  3HOY L;  1R9T L;  2NVX L;  3HOV L;  2NVT L;  5IYC L;  4AYB P;  4C3J L;  5IYB L;  3HOU L;  5M3M L;  4A3F L;  2E2I L;  2NVQ L;  3I4M L;  3S16 L;  3S1Q L;  5C3E L;  5IP7 L;  5C44 L;  1WCM L;  3GTL L;  1TWF L;  2Y0S P;  3GTQ L;  1Y1W L;  2B63 L;  1I3Q L;  3S1R L;  2WB1 P;  4A3L L;  4A93 L;  2YU9 L;  4C3I L;  5M5X L;  1TWC L;  3CQZ L;  2WAQ P;  3S1N L;  3HKZ P;  3GTG L;  4A3K L;  4Y52 L;  3I4N L;  4X6A L;  3S2H L;  3HOZ L;  2NVY L;  4BBR L;  2E2J L;  3S17 L;  3GTM L;  2JA8 L;  4BY7 L;  3K7A L;  1TWA L;  5IP9 L;  4BXX L;  4A3M L;  3H3V M;  2R92 L;  3GTP L;  3FKI L;  2JA6 L;  5M3F L;  1I6H L;  3M3Y L;  4A3I L;  3PO3 L;  1I50 L;  2VUM L;  4A3B L;  4A3C L;  4BY1 L;  3M4O L;  3GTO L;  3S1M L;  1SFO L;  4BBS L;  2PMZ P;  4C2M 1;  2R93 L;  3RZO L;  3HOX L;  3S2D L;  4C3H L;  4Y7N L;  1K83 L;  1TWG L;  2JA7 L;  5FLM L;  3HOW L;  2JA5 L;  3S15 L;  1Y1V L;  2E2H L;  3GTK L;  3GTJ L;  5C4X L;  4A3J L;  5C4J L;  2R7Z L; 
#chains in the Genus database with same CATH topology
 1IRN A;  5FJ8 L;  3MQK B;  2XJQ A;  3H0G L;  1BE7 A;  4QIW P;  1TWH L;  7RXN A;  2Z3R B;  4AHZ A;  3PO2 L;  4AR6 A;  4A3G L;  1FHM A;  1RDV A;  3HOY L;  2HR5 A;  2NVX L;  4AR5 A;  1BRF A;  2XJR A;  4C3J L;  3HOU L;  5M3M L;  4E6Y A;  2NVQ L;  4JAG A;  4JAD A;  3S1Q L;  5C3E L;  1PFW A;  1TWF L;  3GTQ L;  3FDJ A;  2B63 L;  1R0G A;  3S1R L;  2WB1 P;  1QCV A;  4YWL A;  2NYD A;  5M5X L;  1TWC L;  5AI3 A;  2RDV A;  3LWR B;  3SS2 A;  3HJW B;  4A3K L;  2PVE A;  3I4N L;  2PYA A;  1YV1 A;  1VCX A;  4XXB B;  1VZG A;  2E2J L;  3S17 L;  1B2O A;  5K2M E;  5IP9 L;  2MS3 A;  4A3M L;  1SMU A;  4GS7 D;  2PPT A;  3LPE B;  2M6O A;  2VUM L;  2C6B A;  3GTO L;  1P7P A;  2PMZ P;  4C2M 1;  5AI2 A;  4Y7N L;  1TWG L;  1SMW A;  1T9Q A;  1NXG A;  1Y1V L;  1R0H A;  3GTK L;  3PZA A;  5C4J L;  4AI1 A;  4G6B A;  5IYD L;  1BQ9 A;  5M5W L;  3J7Z 1;  4A3D L;  5MFP A;  4A3E L;  3S14 L;  3LWQ B;  1BQ8 A;  1IU6 A;  1R9T L;  2A6E D;  3MSU A;  1IRO A;  2A6H D;  1JYB A;  1T9P A;  1CAA A;  2CKA A;  5IYB L;  3QQC E;  1PFY A;  2E2I L;  2XJP A;  4U67 1;  4JAE A;  5IP7 L;  1WCM L;  1I3Q L;  4TPU A;  2K2D A;  5GAH c;  5JVH 1;  5H1S c;  4A3L L;  4AI2 A;  4LHN A;  1QYB A;  4K9F A;  4C3I L;  6RXN A;  3HAX C;  2ERS A;  3CQZ L;  3HKZ P;  1YK5 A;  1R0I A;  2AQC A;  1QQT A;  2ERJ A;  4TVM A;  3GTM L;  2M4Y A;  2JA8 L;  1TWA L;  5MF6 A;  4BXX L;  2A69 D;  3PKJ A;  2R92 L;  1E8J A;  2GMG A;  3GTP L;  2CKC A;  3B08 B;  1PFU A;  3P2A A;  4POG A;  1OWB A;  4A3I L;  2XJT A;  8RXN A;  1I50 L;  1LTL A;  3PL5 A;  4A3C L;  5GAD c;  3M4O L;  4LHL A;  3H9C A;  4AR4 A;  2ZIX A;  3PKI A;  2DSX A;  3HOX L;  3S2D L;  1B71 A;  1K83 L;  4JAF A;  2JA5 L;  2PVX A;  2KN9 A;  3VPB E;  1WJV A;  2CR8 A;  5C4X L;  1LKM A;  3IU3 I;  2R7Z L;  1BFY A;  3WWN B;  3RZD L;  4AHX A;  3KYV A;  5AN9 H;  3ZG6 A;  1PFV A;  3KYY A;  3J7Y 1;  2B5I D;  1DX8 A;  5DM6 1;  5M5Y L;  1H7V A;  1VZI A;  1FHH A;  3P8B A;  4POF A;  5MFZ A;  4AI3 A;  4B8C D;  4A3F L;  3RYG A;  2V0E A;  1NXE A;  3I4M L;  1S24 A;  1F4L A;  2JI2 A;  2JI3 A;  3PWF A;  3S16 L;  3GTL L;  3H97 A;  2YU9 L;  3KYU A;  3LWP B;  3S1N L;  2WAQ P;  1R0F A;  2J9U B;  1RWD A;  4Y52 L;  4AI0 A;  2XJS A;  3MPS A;  4YWM A;  1YUZ A;  1RB9 A;  5EIO C;  3S2H L;  3HOZ L;  2NVY L;  5JVG 1;  2V3B B;  4BY7 L;  4RXN A;  3QVD A;  2V0F A;  3H3V M;  2VL6 A;  2AUS B;  2H12 A;  3FKI L;  2JA6 L;  1IW7 D;  4A3B L;  2A68 D;  3B0A B;  4BY1 L;  5EIN C;  2PSM C;  2R93 L;  3RZO L;  4V19 6;  1PZX A;  1VZH A;  2AYJ A;  1NNQ A;  2M6P A;  2Z3Q B;  2JA7 L;  1RYQ A;  3RZT A;  3S15 L;  2M4V A;  2E2H L;  5MLC 3;  3GTJ L;  1YUX A;  1S30 A;  1R0J A;  2KKD A;  1DVB A;  2RFK B;  4AHY A;  2C6A A;  5IY0 A;  2BE5 D;  1OWC A;  2LCQ A;  1ODH A;  5MGN A;  3K35 A;  2APO B;  3HOV L;  3LNL A;  2NVT L;  5IYC L;  5RXN A;  4AYB P;  1RYT A;  3HJY B;  4AHW A;  1B2J A;  2JI1 A;  2HVY C;  2EY4 E;  2QL0 A;  5GAG c;  5C44 L;  2Y0S P;  1Y1W L;  3A44 A;  1SMM A;  3H9B A;  5GAE c;  4A93 L;  5DM7 1;  1T9O A;  1YK4 A;  4ME3 A;  3GTG L;  1IU5 A;  4X6A L;  4WFN 1;  3H99 A;  4BBR L;  3KYX A;  4UY8 1;  1CAD A;  3KYW A;  2XJV A;  3WWL A;  2L0Z A;  3LWV B;  5M3F L;  1I6H L;  1C09 A;  3M3Y L;  4XGH A;  3PO3 L;  4ZN3 B;  4AR3 A;  2XJU A;  1B13 A;  3S1M L;  3JR7 A;  1SFO L;  4BBS L;  2O5J D;  3RZ6 A;  4C3H L;  3PIP 1;  1LKP A;  3HOW L;  3NFP I;  5FLM L;  1ZRP A;  1LKO A;  3PIO 1;  3LWO B;  4ZN1 B;  1RDG A;  1S2Z A;  1Z92 B;  4A3J L;  3K7A L; 
#chains in the Genus database with same CATH homology
 5FJ8 L;  3RZD L;  5IYD L;  5M5W L;  4A3D L;  3H0G L;  4QIW P;  4A3E L;  1TWH L;  3S14 L;  3PO2 L;  4A3G L;  5M5Y L;  3HOY L;  1R9T L;  2NVX L;  3HOV L;  2NVT L;  5IYC L;  4AYB P;  4C3J L;  5IYB L;  3HOU L;  5M3M L;  4A3F L;  2E2I L;  2NVQ L;  3I4M L;  3S16 L;  3S1Q L;  5C3E L;  5IP7 L;  5C44 L;  1WCM L;  3GTL L;  1TWF L;  2Y0S P;  3GTQ L;  1Y1W L;  2B63 L;  1I3Q L;  3S1R L;  2WB1 P;  4A3L L;  4A93 L;  2YU9 L;  4C3I L;  5M5X L;  1TWC L;  3CQZ L;  2WAQ P;  3S1N L;  3HKZ P;  3GTG L;  4A3K L;  4Y52 L;  3I4N L;  4X6A L;  3S2H L;  3HOZ L;  2NVY L;  4BBR L;  2E2J L;  3S17 L;  3GTM L;  2JA8 L;  4BY7 L;  3K7A L;  1TWA L;  5IP9 L;  4BXX L;  4A3M L;  3H3V M;  2R92 L;  3GTP L;  3FKI L;  2JA6 L;  5M3F L;  1I6H L;  3M3Y L;  4A3I L;  3PO3 L;  1I50 L;  2VUM L;  4A3B L;  4A3C L;  4BY1 L;  3M4O L;  3GTO L;  3S1M L;  1SFO L;  4BBS L;  2PMZ P;  4C2M 1;  2R93 L;  3RZO L;  3HOX L;  3S2D L;  4C3H L;  4Y7N L;  1K83 L;  1TWG L;  2JA7 L;  5FLM L;  3HOW L;  2JA5 L;  3S15 L;  1Y1V L;  2E2H L;  3GTK L;  3GTJ L;  5C4X L;  4A3J L;  5C4J L;  2R7Z L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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