4A3EL

Rna polymerase ii initial transcribing complex with a 5nt dna-rna hybrid and soaked with ampcpp
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3eL00
3HOZL 3H0GL 2JA8L 3HOXL 2E2HL 3K7AL 3S1RL 4A3GL 3HKZP 1TWFL 1TWCL 3FKIL 4BXXL 4A3FL 3GTPL 4X6AL 5C4XL 1Y1VL 3PO2L 4C3HL 4A3CL 4A93L 4AYBP 5C4JL 2NVTL 2YU9L 3S16L 5IYCL 5M5YL 1R9TL 3GTLL 3HOYL 4A3EL 2PMZP 5C3EL 4BBSL 3PO3L 3HOUL 3GTML 2E2IL 1TWHL 2NVQL 3GTJL 1I50L 4BBRL 2VUML 5M3FL 4A3BL 4A3IL 1TWGL 5IYDL 3GTKL 2B63L 4BY1L 4BY7L 1Y1WL 3M4OL 1I3QL 2JA7L 3S2HL 4A3DL 2JA5L 3I4NL 4C3IL 3HOVL 1K83L 5M3ML 3GTOL 5IP9L 3HOWL 4C3JL 4C2M1 3S2DL 5M5XL 1SFOL 3S17L 2NVYL 5IYBL 3RZOL 4QIWP 5FLML 4Y7NL 4Y52L 2R7ZL 3GTQL 2JA6L 1I6HL 2R93L 3S1NL 5FJ8L 2WB1P 3RZDL 3S15L 3M3YL 5IP7L 4A3JL 1TWAL 4A3ML 2NVXL 3I4ML 3H3VM 3S1QL 3GTGL 2R92L 4A3LL 2WAQP 4A3KL 2E2JL 3S1ML 3CQZL 5M5WL 1WCML 3S14L 2Y0SP 5C44L
chains in the Genus database with same CATH superfamily
3PIO1 1VZHA 3H0GL 4AHXA 2JA8L 3MPSA 5GADc 4A3GL 2V0EA 1TWFL 1TWCL 3GTPL 1BFYA 1R0FA 1DX8A 5AN9H 4JAEA 4B8CD 4AYBP 3LWQB 2Z3RB 3KYVA 4AHZA 5MFPA 3LWVB 1S2ZA 1SMWA 3PO3L 1B2OA 3MSUA 2PPTA 3VPBE 3GTML 1YUZA 5AI3A 2BE5D 1SMUA 3GTKL 1BE7A 3WWLA 4BY7L 1IW7D 1F4LA 1B2JA 4A3DL 1R0GA 4C3IL 4G6BA 3HOVL 3KYWA 3WWNB 5AI2A 5DM61 1RB9A 5GAEc 2AYJA 3ZG6A 3RZOL 5IYBL 2LCQA 4ZN1B 4WFN1 4Y52L 3GTQL 4LHLA 2R93L 1NXGA 2CKCA 4A3JL 1H7VA 1T9OA 1QQTA 1RYQA 2ERSA 2XJPA 3H3VM 3S1QL 1T9QA 3B0AB 2E2JL 1OWCA 5H1Sc 3QVDA 1WCML 2A6ED 2B5ID 5C44L 4JAFA 1RWDA 1PZXA 4AR6A 3K7AL 3K35A 7RXNA 2KKDA 4AR5A 2L0ZA 4RXNA 1PFUA 3HKZP 4A3FL 3FKIL 2M6OA 4AR4A 1Y1VL 3KYXA 4AI1A 2C6AA 2J9UB 2PVEA 3J7Y1 4A3CL 4AR3A 1WJVA 5C4JL 4POGA 4TVMA 2NVTL 2APOB 3S16L 4V196 2XJUA 4AI0A 1QCVA 3HOYL 1IU5A 3KYYA 2JI2A 4GS7D 2PVXA 2XJQA 1TWHL 1PFWA 2NVQL 4BBRL 2JI1A 2CR8A 3JR7A 5M3FL 4A3IL 1VCXA 1CADA 2Z3QB 4BY1L 4POFA 2JA7L 3S2HL 1BQ8A 1ZRPA 2JI3A 2ZIXA 2RFKB 2O5JD 3PKJA 3S17L 2XJVA 2NVYL 4QIWP 2QL0A 2H12A 4Y7NL 1VZGA 2M4YA 2R7ZL 2JA6L 1I6HL 3FDJA 3RZDL 1OWBA 1FHHA 3S15L 1YV1A 3M3YL 1B13A 5IP7L 3QQCE 4A3ML 2PYAA 2DSXA 2M6PA 5MFZA 5GAHc 3I4ML 1LKMA 1RDGA 1VZIA 2C6BA 1YK4A 3S14L 1YK5A 3RZ6A 3P8BA 2NYDA 1YUXA 5MGNA 2E2HL 3KYUA 1QYBA 1IRNA 3H9BA 4ZN3B 1PFVA 3S1RL 1E8JA 4YWLA 1JYBA 4X6AL 1B71A 4JADA 4LHNA 4C3HL 1BRFA 2A69D 4K9FA 5IY0A 3LNLA 2XJTA 2K2DA 5RXNA 2YU9L 2KN9A 5IYCL 1DVBA 1R9TL 1Z92B 3LWOB 2CKAA 4A3EL 2PMZP 5C3EL 5EINC 5K2ME 4BBSL 1ODHA 3GTJL 2A68D 1C09A 1IROA 1S24A 5IYDL 3H9CA 5JVH1 3LWRB 2HVYC 4UY81 3M4OL 3LWPB 1I3QL 1P7PA 2M4VA 3RYGA 1IU6A 3J7Z1 1K83L 3GTOL 3PIP1 5IP9L 2ERJA 3PL5A 3S2DL 4C3JL 4TPUA 4C2M1 3MQKB 3SS2A 1LTLA 5MF6A 6RXNA 5FJ8L 1FHMA 1RYTA 1TWAL 3P2AA 3HJYB 4AI3A 4AHWA 1T9PA 1LKOA 3GTGL 4XGHA 1CAAA 2WAQP 2XJRA 2A6HD 2VL6A 3S1ML 3RZTA 4U671 5EIOC 1R0HA 3HOZL 3PZAA 3HOXL 3NFPI 4BXXL 3A44A 5C4XL 3PO2L 2EY4E 3PKIA 4YWMA 2RDVA 4E6YA 4A93L 1LKPA 3LPEB 3HAXC 5M5YL 2GMGA 1RDVA 3GTLL 4AI2A 1R0IA 5DM71 3HOUL 1BQ9A 2E2IL 2AUSB 1S30A 1I50L 2V3BB 2VUML 3PWFA 4A3BL 1TWGL 2B63L 1Y1WL 1NNQA 2XJSA 2PSMC 2JA5L 3I4NL 3IU3I 3H99A 5M3ML 2HR5A 3HOWL 1SFOL 5M5XL 5FLML 4JAGA 3HJWB 3S1NL 1NXEA 2AQCA 2WB1P 1PFYA 3H97A 5MLC3 5JVG1 4XXBB 2NVXL 3B08B 2MS3A 4ME3A 2R92L 1SMMA 4A3LL 1R0JA 8RXNA 4A3KL 4AHYA 5GAGc 2V0FA 3CQZL 5M5WL 2Y0SP
chains in the Genus database with same CATH topology
3HOZL 3H0GL 2JA8L 3HOXL 2E2HL 3K7AL 3S1RL 4A3GL 3HKZP 1TWFL 1TWCL 3FKIL 4BXXL 4A3FL 3GTPL 4X6AL 5C4XL 1Y1VL 3PO2L 4C3HL 4A3CL 4A93L 4AYBP 5C4JL 2NVTL 2YU9L 3S16L 5IYCL 5M5YL 1R9TL 3GTLL 3HOYL 4A3EL 2PMZP 5C3EL 4BBSL 3PO3L 3HOUL 3GTML 2E2IL 1TWHL 2NVQL 3GTJL 1I50L 4BBRL 2VUML 5M3FL 4A3BL 4A3IL 1TWGL 5IYDL 3GTKL 2B63L 4BY1L 4BY7L 1Y1WL 3M4OL 1I3QL 2JA7L 3S2HL 4A3DL 2JA5L 3I4NL 4C3IL 3HOVL 1K83L 5M3ML 3GTOL 5IP9L 3HOWL 4C3JL 4C2M1 3S2DL 5M5XL 1SFOL 3S17L 2NVYL 5IYBL 3RZOL 4QIWP 5FLML 4Y7NL 4Y52L 2R7ZL 3GTQL 2JA6L 1I6HL 2R93L 3S1NL 5FJ8L 2WB1P 3RZDL 3S15L 3M3YL 5IP7L 4A3JL 1TWAL 4A3ML 2NVXL 3I4ML 3H3VM 3S1QL 3GTGL 2R92L 4A3LL 2WAQP 4A3KL 2E2JL 3S1ML 3CQZL 5M5WL 1WCML 3S14L 2Y0SP 5C44L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOZ L;  3H0G L;  2JA8 L;  3HOX L;  2E2H L;  3K7A L;  3S1R L;  4A3G L;  3HKZ P;  1TWF L;  1TWC L;  3FKI L;  4BXX L;  4A3F L;  3GTP L;  4X6A L;  5C4X L;  1Y1V L;  3PO2 L;  4C3H L;  4A3C L;  4A93 L;  4AYB P;  5C4J L;  2NVT L;  2YU9 L;  3S16 L;  5IYC L;  5M5Y L;  1R9T L;  3GTL L;  3HOY L;  4A3E L;  2PMZ P;  5C3E L;  4BBS L;  3PO3 L;  3HOU L;  3GTM L;  2E2I L;  1TWH L;  2NVQ L;  3GTJ L;  1I50 L;  4BBR L;  2VUM L;  5M3F L;  4A3B L;  4A3I L;  1TWG L;  5IYD L;  3GTK L;  2B63 L;  4BY1 L;  4BY7 L;  1Y1W L;  3M4O L;  1I3Q L;  2JA7 L;  3S2H L;  4A3D L;  2JA5 L;  3I4N L;  4C3I L;  3HOV L;  1K83 L;  5M3M L;  3GTO L;  5IP9 L;  3HOW L;  4C3J L;  4C2M 1;  3S2D L;  5M5X L;  1SFO L;  3S17 L;  2NVY L;  5IYB L;  3RZO L;  4QIW P;  5FLM L;  4Y7N L;  4Y52 L;  2R7Z L;  3GTQ L;  2JA6 L;  1I6H L;  2R93 L;  3S1N L;  5FJ8 L;  2WB1 P;  3RZD L;  3S15 L;  3M3Y L;  5IP7 L;  4A3J L;  1TWA L;  4A3M L;  2NVX L;  3I4M L;  3H3V M;  3S1Q L;  3GTG L;  2R92 L;  4A3L L;  2WAQ P;  4A3K L;  2E2J L;  3S1M L;  3CQZ L;  5M5W L;  1WCM L;  3S14 L;  2Y0S P;  5C44 L; 
#chains in the Genus database with same CATH topology
 3PIO 1;  1VZH A;  3H0G L;  4AHX A;  2JA8 L;  3MPS A;  5GAD c;  4A3G L;  2V0E A;  1TWF L;  1TWC L;  3GTP L;  1BFY A;  1R0F A;  1DX8 A;  5AN9 H;  4JAE A;  4B8C D;  4AYB P;  3LWQ B;  2Z3R B;  3KYV A;  4AHZ A;  5MFP A;  3LWV B;  1S2Z A;  1SMW A;  3PO3 L;  1B2O A;  3MSU A;  2PPT A;  3VPB E;  3GTM L;  1YUZ A;  5AI3 A;  2BE5 D;  1SMU A;  3GTK L;  1BE7 A;  3WWL A;  4BY7 L;  1IW7 D;  1F4L A;  1B2J A;  4A3D L;  1R0G A;  4C3I L;  4G6B A;  3HOV L;  3KYW A;  3WWN B;  5AI2 A;  5DM6 1;  1RB9 A;  5GAE c;  2AYJ A;  3ZG6 A;  3RZO L;  5IYB L;  2LCQ A;  4ZN1 B;  4WFN 1;  4Y52 L;  3GTQ L;  4LHL A;  2R93 L;  1NXG A;  2CKC A;  4A3J L;  1H7V A;  1T9O A;  1QQT A;  1RYQ A;  2ERS A;  2XJP A;  3H3V M;  3S1Q L;  1T9Q A;  3B0A B;  2E2J L;  1OWC A;  5H1S c;  3QVD A;  1WCM L;  2A6E D;  2B5I D;  5C44 L;  4JAF A;  1RWD A;  1PZX A;  4AR6 A;  3K7A L;  3K35 A;  7RXN A;  2KKD A;  4AR5 A;  2L0Z A;  4RXN A;  1PFU A;  3HKZ P;  4A3F L;  3FKI L;  2M6O A;  4AR4 A;  1Y1V L;  3KYX A;  4AI1 A;  2C6A A;  2J9U B;  2PVE A;  3J7Y 1;  4A3C L;  4AR3 A;  1WJV A;  5C4J L;  4POG A;  4TVM A;  2NVT L;  2APO B;  3S16 L;  4V19 6;  2XJU A;  4AI0 A;  1QCV A;  3HOY L;  1IU5 A;  3KYY A;  2JI2 A;  4GS7 D;  2PVX A;  2XJQ A;  1TWH L;  1PFW A;  2NVQ L;  4BBR L;  2JI1 A;  2CR8 A;  3JR7 A;  5M3F L;  4A3I L;  1VCX A;  1CAD A;  2Z3Q B;  4BY1 L;  4POF A;  2JA7 L;  3S2H L;  1BQ8 A;  1ZRP A;  2JI3 A;  2ZIX A;  2RFK B;  2O5J D;  3PKJ A;  3S17 L;  2XJV A;  2NVY L;  4QIW P;  2QL0 A;  2H12 A;  4Y7N L;  1VZG A;  2M4Y A;  2R7Z L;  2JA6 L;  1I6H L;  3FDJ A;  3RZD L;  1OWB A;  1FHH A;  3S15 L;  1YV1 A;  3M3Y L;  1B13 A;  5IP7 L;  3QQC E;  4A3M L;  2PYA A;  2DSX A;  2M6P A;  5MFZ A;  5GAH c;  3I4M L;  1LKM A;  1RDG A;  1VZI A;  2C6B A;  1YK4 A;  3S14 L;  1YK5 A;  3RZ6 A;  3P8B A;  2NYD A;  1YUX A;  5MGN A;  2E2H L;  3KYU A;  1QYB A;  1IRN A;  3H9B A;  4ZN3 B;  1PFV A;  3S1R L;  1E8J A;  4YWL A;  1JYB A;  4X6A L;  1B71 A;  4JAD A;  4LHN A;  4C3H L;  1BRF A;  2A69 D;  4K9F A;  5IY0 A;  3LNL A;  2XJT A;  2K2D A;  5RXN A;  2YU9 L;  2KN9 A;  5IYC L;  1DVB A;  1R9T L;  1Z92 B;  3LWO B;  2CKA A;  4A3E L;  2PMZ P;  5C3E L;  5EIN C;  5K2M E;  4BBS L;  1ODH A;  3GTJ L;  2A68 D;  1C09 A;  1IRO A;  1S24 A;  5IYD L;  3H9C A;  5JVH 1;  3LWR B;  2HVY C;  4UY8 1;  3M4O L;  3LWP B;  1I3Q L;  1P7P A;  2M4V A;  3RYG A;  1IU6 A;  3J7Z 1;  1K83 L;  3GTO L;  3PIP 1;  5IP9 L;  2ERJ A;  3PL5 A;  3S2D L;  4C3J L;  4TPU A;  4C2M 1;  3MQK B;  3SS2 A;  1LTL A;  5MF6 A;  6RXN A;  5FJ8 L;  1FHM A;  1RYT A;  1TWA L;  3P2A A;  3HJY B;  4AI3 A;  4AHW A;  1T9P A;  1LKO A;  3GTG L;  4XGH A;  1CAA A;  2WAQ P;  2XJR A;  2A6H D;  2VL6 A;  3S1M L;  3RZT A;  4U67 1;  5EIO C;  1R0H A;  3HOZ L;  3PZA A;  3HOX L;  3NFP I;  4BXX L;  3A44 A;  5C4X L;  3PO2 L;  2EY4 E;  3PKI A;  4YWM A;  2RDV A;  4E6Y A;  4A93 L;  1LKP A;  3LPE B;  3HAX C;  5M5Y L;  2GMG A;  1RDV A;  3GTL L;  4AI2 A;  1R0I A;  5DM7 1;  3HOU L;  1BQ9 A;  2E2I L;  2AUS B;  1S30 A;  1I50 L;  2V3B B;  2VUM L;  3PWF A;  4A3B L;  1TWG L;  2B63 L;  1Y1W L;  1NNQ A;  2XJS A;  2PSM C;  2JA5 L;  3I4N L;  3IU3 I;  3H99 A;  5M3M L;  2HR5 A;  3HOW L;  1SFO L;  5M5X L;  5FLM L;  4JAG A;  3HJW B;  3S1N L;  1NXE A;  2AQC A;  2WB1 P;  1PFY A;  3H97 A;  5MLC 3;  5JVG 1;  4XXB B;  2NVX L;  3B08 B;  2MS3 A;  4ME3 A;  2R92 L;  1SMM A;  4A3L L;  1R0J A;  8RXN A;  4A3K L;  4AHY A;  5GAG c;  2V0F A;  3CQZ L;  5M5W L;  2Y0S P; 
#chains in the Genus database with same CATH homology
 3HOZ L;  3H0G L;  2JA8 L;  3HOX L;  2E2H L;  3K7A L;  3S1R L;  4A3G L;  3HKZ P;  1TWF L;  1TWC L;  3FKI L;  4BXX L;  4A3F L;  3GTP L;  4X6A L;  5C4X L;  1Y1V L;  3PO2 L;  4C3H L;  4A3C L;  4A93 L;  4AYB P;  5C4J L;  2NVT L;  2YU9 L;  3S16 L;  5IYC L;  5M5Y L;  1R9T L;  3GTL L;  3HOY L;  4A3E L;  2PMZ P;  5C3E L;  4BBS L;  3PO3 L;  3HOU L;  3GTM L;  2E2I L;  1TWH L;  2NVQ L;  3GTJ L;  1I50 L;  4BBR L;  2VUM L;  5M3F L;  4A3B L;  4A3I L;  1TWG L;  5IYD L;  3GTK L;  2B63 L;  4BY1 L;  4BY7 L;  1Y1W L;  3M4O L;  1I3Q L;  2JA7 L;  3S2H L;  4A3D L;  2JA5 L;  3I4N L;  4C3I L;  3HOV L;  1K83 L;  5M3M L;  3GTO L;  5IP9 L;  3HOW L;  4C3J L;  4C2M 1;  3S2D L;  5M5X L;  1SFO L;  3S17 L;  2NVY L;  5IYB L;  3RZO L;  4QIW P;  5FLM L;  4Y7N L;  4Y52 L;  2R7Z L;  3GTQ L;  2JA6 L;  1I6H L;  2R93 L;  3S1N L;  5FJ8 L;  2WB1 P;  3RZD L;  3S15 L;  3M3Y L;  5IP7 L;  4A3J L;  1TWA L;  4A3M L;  2NVX L;  3I4M L;  3H3V M;  3S1Q L;  3GTG L;  2R92 L;  4A3L L;  2WAQ P;  4A3K L;  2E2J L;  3S1M L;  3CQZ L;  5M5W L;  1WCM L;  3S14 L;  2Y0S P;  5C44 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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