4A3KL

Rna polymerase ii initial transcribing complex with a 7nt dna-rna hybrid
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Initial RNA Polymerase II Transcription.
pubmed doi rcsb
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
molecule tags Transcription
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a3kL00
4A3ML 5M3ML 2WB1P 1R9TL 3S1ML 5C4JL 1TWGL 1SFOL 2JA6L 3FKIL 4A93L 5C44L 2NVQL 3PO3L 3GTJL 4A3JL 3GTGL 3PO2L 3HOWL 4BXXL 3CQZL 3S2DL 3I4ML 2R7ZL 4A3IL 3HKZP 3S16L 2E2IL 1TWFL 2E2HL 5IYBL 3HOVL 3GTPL 4X6AL 3GTLL 4C3HL 5IYDL 3GTML 4AYBP 3RZOL 2NVXL 5M5XL 3H0GL 4C2M1 1Y1VL 2WAQP 4A3GL 4A3DL 5M5YL 4A3CL 4Y52L 3GTOL 4BBSL 2JA8L 2PMZP 1Y1WL 3GTQL 2NVTL 4A3LL 2Y0SP 5IYCL 2VUML 2B63L 2YU9L 5IP9L 1I50L 1TWAL 1WCML 2E2JL 1TWHL 5M3FL 4BBRL 1I6HL 4BY7L 3M3YL 5C4XL 3S1NL 3I4NL 2R92L 5IP7L 4A3BL 3S1RL 3S17L 4C3JL 3K7AL 4C3IL 3HOZL 3H3VM 3HOUL 3S2HL 1K83L 3HOXL 3S1QL 3RZDL 1I3QL 3M4OL 3GTKL 5FJ8L 3S15L 4QIWP 2JA5L 5M5WL 4A3EL 4BY1L 5FLML 4A3KL 2JA7L 1TWCL 3S14L 2R93L 4Y7NL 3HOYL 4A3FL 2NVYL 5C3EL
chains in the Genus database with same CATH superfamily
4AHYA 2KN9A 1RWDA 1SMMA 2XJTA 5AI2A 3B0AB 5C4JL 1RB9A 5EIOC 1SFOL 4AHWA 5JVG1 2JI1A 1FHMA 4ME3A 1IRNA 1IU5A 2HR5A 2M4VA 3GTJL 5GAEc 4BXXL 2DSXA 3H99A 2A69D 3S2DL 5AI3A 2R7ZL 4A3IL 1PFUA 3HKZP 2E2HL 2PSMC 3HOVL 3GTLL 4AI3A 2AQCA 5M5XL 3ZG6A 1E8JA 5MLC3 1Y1VL 1DVBA 3RZ6A 2C6BA 3PKIA 5M5YL 2XJQA 3KYXA 4BBSL 3B08B 3GTQL 3HJWB 4AR3A 2Y0SP 1S24A 5IP9L 1I50L 1TWHL 5GAHc 5H1Sc 4BBRL 3MSUA 1I6HL 4WFN1 1B13A 5JVH1 1F4LA 1BE7A 1QYBA 3PZAA 3PIO1 5GAGc 2XJUA 3K7AL 3RYGA 3HOZL 1NXGA 3H3VM 3S2HL 1ODHA 3M4OL 3GTKL 1T9QA 1SMWA 3S15L 4QIWP 2JA5L 5M5WL 2LCQA 1VCXA 1OWBA 3S14L 3LWVB 5K2ME 5MFPA 1B2JA 2NVYL 3H97A 4A3ML 5M3ML 1FHHA 1ZRPA 3RZTA 1TWGL 2PYAA 2ZIXA 4UY81 2L0ZA 3KYWA 2ERSA 5EINC 4A93L 1IU6A 1LKOA 1S2ZA 5GADc 3H9CA 2GMGA 3GTGL 3HOWL 3PIP1 4JAFA 2APOB 3S16L 2XJSA 3GTPL 4AI2A 3PL5A 4C3HL 3GTML 1LKMA 1PZXA 1C09A 2PVEA 3H0GL 1YK5A 1YV1A 3P2AA 4C2M1 4JADA 2WAQP 4A3CL 2B5ID 2K2DA 1LKPA 1T9OA 3IU3I 2VUML 2CKAA 5MGNA 4AR6A 3J7Z1 2H12A 2M6PA 1R0HA 4ZN3B 1VZIA 3NFPI 3QQCE 1PFVA 1T9PA 3HOXL 1OWCA 3LPEB 4ZN1B 5FJ8L 3J7Y1 2EY4E 4TVMA 1PFYA 4BY1L 4A3KL 2JA7L 3JR7A 4Y7NL 3HJYB 2XJPA 3HOYL 7RXNA 2AYJA 5MF6A 1YK4A 1B2OA 4JAEA 1VZGA 4B8CD 1IROA 1Z92B 3S1ML 3LWPB 2JA6L 3FKIL 5C44L 2NVQL 8RXNA 5AN9H 3PO3L 1B71A 1P7PA 3I4ML 4E6YA 1TWFL 4POGA 3QVDA 2NYDA 3PKJA 4XXBB 1YUXA 1YUZA 5IYDL 2NVXL 2V0FA 2XJVA 4A3GL 4AHXA 4U671 2JA8L 1BQ9A 2PMZP 2NVTL 2JI3A 2QL0A 4YWMA 1SMUA 3PWFA 1TWAL 1CAAA 4AI0A 5C3EL 1WCML 5MFZA 2RDVA 4BY7L 5C4XL 1VZHA 3S1NL 3I4NL 4GS7D 3S1RL 3FDJA 1WJVA 3P8BA 2V0EA 2KKDA 1DX8A 1R0FA 4C3JL 4C3IL 1R0GA 1R0IA 1IW7D 3HOUL 1K83L 3RZDL 2M4YA 2HVYC 2CKCA 3LNLA 1JYBA 5FLML 2JI2A 1NNQA 5IY0A 1BRFA 4V196 2Z3RB 3LWRB 2WB1P 1R9TL 4LHLA 5DM71 2M6OA 2O5JD 1S30A 4LHNA 2PVXA 4AI1A 2BE5D 2Z3QB 3LWOB 4A3JL 1R0JA 4YWLA 3PO2L 1PFWA 2A6ED 3CQZL 3HAXC 2E2IL 2A6HD 5IYBL 3WWNB 5DM61 4X6AL 4AR4A 1BFYA 1RDVA 6RXNA 1RYQA 4AYBP 3RZOL 3H9BA 3K35A 4A3DL 4Y52L 3GTOL 3SS2A 4XGHA 1Y1WL 2XJRA 4A3LL 5IYCL 2J9UB 2B63L 2YU9L 2VL6A 1NXEA 2E2JL 5M3FL 2C6AA 3MPSA 2V3BB 2ERJA 3M3YL 1QQTA 2R92L 2AUSB 5IP7L 4JAGA 4A3BL 5RXNA 1QCVA 4RXNA 1CADA 4K9FA 3S17L 1RDGA 3MQKB 2A68D 1H7VA 1LTLA 3S1QL 2PPTA 1I3QL 4POFA 3KYVA 2RFKB 3KYUA 2CR8A 1RYTA 2MS3A 4A3EL 3VPBE 4TPUA 3LWQB 1TWCL 2R93L 1BQ8A 3KYYA 3WWLA 4A3FL 3A44A 4AHZA 4AR5A 4G6BA
chains in the Genus database with same CATH topology
4A3ML 5M3ML 2WB1P 1R9TL 3S1ML 5C4JL 1TWGL 1SFOL 2JA6L 3FKIL 4A93L 5C44L 2NVQL 3PO3L 3GTJL 4A3JL 3GTGL 3PO2L 3HOWL 4BXXL 3CQZL 3S2DL 3I4ML 2R7ZL 4A3IL 3HKZP 3S16L 2E2IL 1TWFL 2E2HL 5IYBL 3HOVL 3GTPL 4X6AL 3GTLL 4C3HL 5IYDL 3GTML 4AYBP 3RZOL 2NVXL 5M5XL 3H0GL 4C2M1 1Y1VL 2WAQP 4A3GL 4A3DL 5M5YL 4A3CL 4Y52L 3GTOL 4BBSL 2JA8L 2PMZP 1Y1WL 3GTQL 2NVTL 4A3LL 2Y0SP 5IYCL 2VUML 2B63L 2YU9L 5IP9L 1I50L 1TWAL 1WCML 2E2JL 1TWHL 5M3FL 4BBRL 1I6HL 4BY7L 3M3YL 5C4XL 3S1NL 3I4NL 2R92L 5IP7L 4A3BL 3S1RL 3S17L 4C3JL 3K7AL 4C3IL 3HOZL 3H3VM 3HOUL 3S2HL 1K83L 3HOXL 3S1QL 3RZDL 1I3QL 3M4OL 3GTKL 5FJ8L 3S15L 4QIWP 2JA5L 5M5WL 4A3EL 4BY1L 5FLML 4A3KL 2JA7L 1TWCL 3S14L 2R93L 4Y7NL 3HOYL 4A3FL 2NVYL 5C3EL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3M L;  5M3M L;  2WB1 P;  1R9T L;  3S1M L;  5C4J L;  1TWG L;  1SFO L;  2JA6 L;  3FKI L;  4A93 L;  5C44 L;  2NVQ L;  3PO3 L;  3GTJ L;  4A3J L;  3GTG L;  3PO2 L;  3HOW L;  4BXX L;  3CQZ L;  3S2D L;  3I4M L;  2R7Z L;  4A3I L;  3HKZ P;  3S16 L;  2E2I L;  1TWF L;  2E2H L;  5IYB L;  3HOV L;  3GTP L;  4X6A L;  3GTL L;  4C3H L;  5IYD L;  3GTM L;  4AYB P;  3RZO L;  2NVX L;  5M5X L;  3H0G L;  4C2M 1;  1Y1V L;  2WAQ P;  4A3G L;  4A3D L;  5M5Y L;  4A3C L;  4Y52 L;  3GTO L;  4BBS L;  2JA8 L;  2PMZ P;  1Y1W L;  3GTQ L;  2NVT L;  4A3L L;  2Y0S P;  5IYC L;  2VUM L;  2B63 L;  2YU9 L;  5IP9 L;  1I50 L;  1TWA L;  1WCM L;  2E2J L;  1TWH L;  5M3F L;  4BBR L;  1I6H L;  4BY7 L;  3M3Y L;  5C4X L;  3S1N L;  3I4N L;  2R92 L;  5IP7 L;  4A3B L;  3S1R L;  3S17 L;  4C3J L;  3K7A L;  4C3I L;  3HOZ L;  3H3V M;  3HOU L;  3S2H L;  1K83 L;  3HOX L;  3S1Q L;  3RZD L;  1I3Q L;  3M4O L;  3GTK L;  5FJ8 L;  3S15 L;  4QIW P;  2JA5 L;  5M5W L;  4A3E L;  4BY1 L;  5FLM L;  4A3K L;  2JA7 L;  1TWC L;  3S14 L;  2R93 L;  4Y7N L;  3HOY L;  4A3F L;  2NVY L;  5C3E L; 
#chains in the Genus database with same CATH topology
 4AHY A;  2KN9 A;  1RWD A;  1SMM A;  2XJT A;  5AI2 A;  3B0A B;  5C4J L;  1RB9 A;  5EIO C;  1SFO L;  4AHW A;  5JVG 1;  2JI1 A;  1FHM A;  4ME3 A;  1IRN A;  1IU5 A;  2HR5 A;  2M4V A;  3GTJ L;  5GAE c;  4BXX L;  2DSX A;  3H99 A;  2A69 D;  3S2D L;  5AI3 A;  2R7Z L;  4A3I L;  1PFU A;  3HKZ P;  2E2H L;  2PSM C;  3HOV L;  3GTL L;  4AI3 A;  2AQC A;  5M5X L;  3ZG6 A;  1E8J A;  5MLC 3;  1Y1V L;  1DVB A;  3RZ6 A;  2C6B A;  3PKI A;  5M5Y L;  2XJQ A;  3KYX A;  4BBS L;  3B08 B;  3GTQ L;  3HJW B;  4AR3 A;  2Y0S P;  1S24 A;  5IP9 L;  1I50 L;  1TWH L;  5GAH c;  5H1S c;  4BBR L;  3MSU A;  1I6H L;  4WFN 1;  1B13 A;  5JVH 1;  1F4L A;  1BE7 A;  1QYB A;  3PZA A;  3PIO 1;  5GAG c;  2XJU A;  3K7A L;  3RYG A;  3HOZ L;  1NXG A;  3H3V M;  3S2H L;  1ODH A;  3M4O L;  3GTK L;  1T9Q A;  1SMW A;  3S15 L;  4QIW P;  2JA5 L;  5M5W L;  2LCQ A;  1VCX A;  1OWB A;  3S14 L;  3LWV B;  5K2M E;  5MFP A;  1B2J A;  2NVY L;  3H97 A;  4A3M L;  5M3M L;  1FHH A;  1ZRP A;  3RZT A;  1TWG L;  2PYA A;  2ZIX A;  4UY8 1;  2L0Z A;  3KYW A;  2ERS A;  5EIN C;  4A93 L;  1IU6 A;  1LKO A;  1S2Z A;  5GAD c;  3H9C A;  2GMG A;  3GTG L;  3HOW L;  3PIP 1;  4JAF A;  2APO B;  3S16 L;  2XJS A;  3GTP L;  4AI2 A;  3PL5 A;  4C3H L;  3GTM L;  1LKM A;  1PZX A;  1C09 A;  2PVE A;  3H0G L;  1YK5 A;  1YV1 A;  3P2A A;  4C2M 1;  4JAD A;  2WAQ P;  4A3C L;  2B5I D;  2K2D A;  1LKP A;  1T9O A;  3IU3 I;  2VUM L;  2CKA A;  5MGN A;  4AR6 A;  3J7Z 1;  2H12 A;  2M6P A;  1R0H A;  4ZN3 B;  1VZI A;  3NFP I;  3QQC E;  1PFV A;  1T9P A;  3HOX L;  1OWC A;  3LPE B;  4ZN1 B;  5FJ8 L;  3J7Y 1;  2EY4 E;  4TVM A;  1PFY A;  4BY1 L;  4A3K L;  2JA7 L;  3JR7 A;  4Y7N L;  3HJY B;  2XJP A;  3HOY L;  7RXN A;  2AYJ A;  5MF6 A;  1YK4 A;  1B2O A;  4JAE A;  1VZG A;  4B8C D;  1IRO A;  1Z92 B;  3S1M L;  3LWP B;  2JA6 L;  3FKI L;  5C44 L;  2NVQ L;  8RXN A;  5AN9 H;  3PO3 L;  1B71 A;  1P7P A;  3I4M L;  4E6Y A;  1TWF L;  4POG A;  3QVD A;  2NYD A;  3PKJ A;  4XXB B;  1YUX A;  1YUZ A;  5IYD L;  2NVX L;  2V0F A;  2XJV A;  4A3G L;  4AHX A;  4U67 1;  2JA8 L;  1BQ9 A;  2PMZ P;  2NVT L;  2JI3 A;  2QL0 A;  4YWM A;  1SMU A;  3PWF A;  1TWA L;  1CAA A;  4AI0 A;  5C3E L;  1WCM L;  5MFZ A;  2RDV A;  4BY7 L;  5C4X L;  1VZH A;  3S1N L;  3I4N L;  4GS7 D;  3S1R L;  3FDJ A;  1WJV A;  3P8B A;  2V0E A;  2KKD A;  1DX8 A;  1R0F A;  4C3J L;  4C3I L;  1R0G A;  1R0I A;  1IW7 D;  3HOU L;  1K83 L;  3RZD L;  2M4Y A;  2HVY C;  2CKC A;  3LNL A;  1JYB A;  5FLM L;  2JI2 A;  1NNQ A;  5IY0 A;  1BRF A;  4V19 6;  2Z3R B;  3LWR B;  2WB1 P;  1R9T L;  4LHL A;  5DM7 1;  2M6O A;  2O5J D;  1S30 A;  4LHN A;  2PVX A;  4AI1 A;  2BE5 D;  2Z3Q B;  3LWO B;  4A3J L;  1R0J A;  4YWL A;  3PO2 L;  1PFW A;  2A6E D;  3CQZ L;  3HAX C;  2E2I L;  2A6H D;  5IYB L;  3WWN B;  5DM6 1;  4X6A L;  4AR4 A;  1BFY A;  1RDV A;  6RXN A;  1RYQ A;  4AYB P;  3RZO L;  3H9B A;  3K35 A;  4A3D L;  4Y52 L;  3GTO L;  3SS2 A;  4XGH A;  1Y1W L;  2XJR A;  4A3L L;  5IYC L;  2J9U B;  2B63 L;  2YU9 L;  2VL6 A;  1NXE A;  2E2J L;  5M3F L;  2C6A A;  3MPS A;  2V3B B;  2ERJ A;  3M3Y L;  1QQT A;  2R92 L;  2AUS B;  5IP7 L;  4JAG A;  4A3B L;  5RXN A;  1QCV A;  4RXN A;  1CAD A;  4K9F A;  3S17 L;  1RDG A;  3MQK B;  2A68 D;  1H7V A;  1LTL A;  3S1Q L;  2PPT A;  1I3Q L;  4POF A;  3KYV A;  2RFK B;  3KYU A;  2CR8 A;  1RYT A;  2MS3 A;  4A3E L;  3VPB E;  4TPU A;  3LWQ B;  1TWC L;  2R93 L;  1BQ8 A;  3KYY A;  3WWL A;  4A3F L;  3A44 A;  4AHZ A;  4AR5 A;  4G6B A; 
#chains in the Genus database with same CATH homology
 4A3M L;  5M3M L;  2WB1 P;  1R9T L;  3S1M L;  5C4J L;  1TWG L;  1SFO L;  2JA6 L;  3FKI L;  4A93 L;  5C44 L;  2NVQ L;  3PO3 L;  3GTJ L;  4A3J L;  3GTG L;  3PO2 L;  3HOW L;  4BXX L;  3CQZ L;  3S2D L;  3I4M L;  2R7Z L;  4A3I L;  3HKZ P;  3S16 L;  2E2I L;  1TWF L;  2E2H L;  5IYB L;  3HOV L;  3GTP L;  4X6A L;  3GTL L;  4C3H L;  5IYD L;  3GTM L;  4AYB P;  3RZO L;  2NVX L;  5M5X L;  3H0G L;  4C2M 1;  1Y1V L;  2WAQ P;  4A3G L;  4A3D L;  5M5Y L;  4A3C L;  4Y52 L;  3GTO L;  4BBS L;  2JA8 L;  2PMZ P;  1Y1W L;  3GTQ L;  2NVT L;  4A3L L;  2Y0S P;  5IYC L;  2VUM L;  2B63 L;  2YU9 L;  5IP9 L;  1I50 L;  1TWA L;  1WCM L;  2E2J L;  1TWH L;  5M3F L;  4BBR L;  1I6H L;  4BY7 L;  3M3Y L;  5C4X L;  3S1N L;  3I4N L;  2R92 L;  5IP7 L;  4A3B L;  3S1R L;  3S17 L;  4C3J L;  3K7A L;  4C3I L;  3HOZ L;  3H3V M;  3HOU L;  3S2H L;  1K83 L;  3HOX L;  3S1Q L;  3RZD L;  1I3Q L;  3M4O L;  3GTK L;  5FJ8 L;  3S15 L;  4QIW P;  2JA5 L;  5M5W L;  4A3E L;  4BY1 L;  5FLM L;  4A3K L;  2JA7 L;  1TWC L;  3S14 L;  2R93 L;  4Y7N L;  3HOY L;  4A3F L;  2NVY L;  5C3E L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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