4A5WB

Crystal structure of c5b6
Total Genus 96
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
913
structure length
871
Chain Sequence
b'CFCDHYAWTQWTSCSKTCNSGTQSRHRQIVVDKYYQENFCEQICSKQETRECNWQRCPINCLLGDFGPWSDCDPCIEKQSKVRSVLRPSQFGGQPCTAPLVAFQPCIPSKLCKIEEADCKNKFRCDSGRCIARKLECNGENDCGDNSDERDCGRTKAVCTRKYNPIPSVQLMGNGFHFLAGEPRGEVLDNSFTGGICKTVKSSRTSNPYRVPANLENVGFEVQTAEDDLKTDFYKDLTSLQGGSSFSVPIFYSSKRSENINHNSAFKQAIQASHKKDSSFIRIHKVMKVLNFTTKAKDLHLSDVFLKALNHLPLEYNSALYSRIFDDFGTHYFTSGSLGGVYDLLYQFSSEELKNSGLTEEEAKHCVRIETHRCTTNKLSEKHEGSFIQGAEKSISLIRGGEEKTFSEWLESVKENPAVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPTLSGTECLCVCQSGTYGENCEKQSPDYKSNAVDGQWGCWSSWSTCDATYKRSRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIMENNGQPCINDDEEMKEVDLPEIEADSGCPQPVPPENGFIRNEKQLYLVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRTECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTCQGNSWTPPISNSLTCEKDTLTKLKGHCQLGQKQSGSECICMSPEEDCSHHSEDLCVFDTDSNDYFTSPACKFLAEKCLNNQQLHFLHIGSCQDGRQLEWGLERTRLSSNSTKKESCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKMGSSTSEKTLNICEVGTIRCANRKMEILHPGKCLA'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords COMPLEMENT C5
publication title Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
pubmed doi rcsb
molecule tags Immune system
total genus 96
structure length 871
sequence length 913
ec nomenclature
pdb deposition date 2011-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00057 Ldl_recept_a Low-density lipoprotein receptor domain class A
B PF00084 Sushi Sushi repeat (SCR repeat)
B PF00090 TSP_1 Thrombospondin type 1 domain
B PF01823 MACPF MAC/Perforin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 4a5wB03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 4a5wB04
2.20.100.10 Mainly Beta Single Sheet TSP-1 type 1 repeat Thrombospondin type-1 (TSP1) repeat 4a5wB01
2XRBA 2RL0A 1HFHA 1OK9A 2O39C 1G4GA 3OP8A 2JGXA 3EJHA 4FXGG 1HCCA 3SW0X 1OK3A 2RLQA 3KZJA 4AYDA 2EC3A 4ZH1D 5HZPB 1UOTP 3ZD1A 2YBYA 2A55A 1SRZA 1HFIA 1H03P 1VEXA 3R6BA 3VDLA 3ZD2A 1SZLA 1GKNA 1G4FA 3VDKA 4HQNA 2W81A 2RKZA 2RKYA 4MUCA 1TPNA 1Z92B 4A5WB 2IZ4A 2KRIA 1OJVA 5HYTB 4K12A 1QGBA 2JRAA 5I0QB 2CG7A 2W80A 3IX0A 3M7PA 1GHQB 4CSYA 2JGWA 1ZJKA 1MD7A 1PPQA 4HQOA 2ERJA 2WIIC 1U5MA 1OK2A 1Q3XA 1ELVA 3OXUD 2YRAA 4C16A 1VVDA 3O8EB 4IGDA 2XWJI 1CKLA 3RJ3D 1VVCA 3CALA 1H2QP 1E8BA 3OEDC 4B2RA 3IU3I 4KKDA 1GPZA 2BZMA 4AYMA 3MQLA 3GOVA 1MD8A 2KMSA 2RLPA 3TVJA 1TPGA 1SS2A 3NFPI 1LSLA 2V8EA 3T5OA 2CG6A 4F4OC 2G7IA 1E88A 1NWVA 3ZRZA 5JPMG 1H2PP 4ONTD 4LOSA 2QY0A 4WJG2 4YNXA 4AYEA 1C1ZA 2B5ID 2XRDA 4LOTA 2XWBF 5FO8C 4HQLA 3GXEA 3VDJA 1OJWA 1H04P 1LY2A 1OJYA 4DJZA 1FBRA 2CKUA 4JHSA 4PZ5A 2XQWC 2EHFA 4J38B 2IZ3A 1O9AA 4AYIA 5HYPA 1QO6A 2MCZA 3L89M 2UWNA 1QUBA 1GKGA 2LOJA 1E5GA 3INBC 1TPMA 4B2SA 2MCYA 1OK1A 3KXVA 5HYUB 3R62A 3ERBA
chains in the Genus database with same CATH superfamily
2XRBA 2RL0A 1HFHA 1OK9A 2I2LA 2O39C 1G4GA 3OP8A 2JGXA 3F6KA 3EJHA 4FXGG 1HCCA 3SW0X 3FGTA 1OK3A 2RLQA 3KZJA 3VWOA 4AYDA 2EC3A 4ZH1D 4YIZA 5HZPB 1UOTP 3ZD1A 2YBYA 2A55A 1SRZA 1HFIA 1H03P 1VEXA 3WSXA 4BWCA 3R6BA 3VDLA 3ZD2A 1SZLA 1GKNA 1G4FA 3VDKA 4HQNA 2W81A 2RKZA 2RKYA 4MUCA 2Y8TA 1TPNA 1Z92B 4A5WB 4APLA 2IZ4A 3ZLDA 2KRIA 1OJVA 3K3TA 5HYTB 4K12A 1QGBA 2JRAA 1RLHA 2Y8SA 5I0QB 2CG7A 2W80A 3IX0A 4N7EA 3M7PA 1GHQB 4CSYA 2JGWA 1ZJKA 1MD7A 1PPQA 4HQOA 2ERJA 2WIIC 1U5MA 1OK2A 1Q3XA 1ELVA 3OXUD 2YRAA 4C16A 1VVDA 3O8EB 4IGDA 2XWJI 1CKLA 3RJ3D 1VVCA 3CALA 1H2QP 1E8BA 3OEDC 5DN4A 4B2RA 3IU3I 4KKDA 1GPZA 2BZMA 4AYMA 3MQLA 3GOVA 3ZLEA 1MD8A 2KMSA 2RLPA 3TVJA 1TPGA 1SS2A 3NFPI 1LSLA 2V8EA 3T5OA 2CG6A 4F4OC 3NJAA 2G7IA 1E88A 1NWVA 3ZRZA 5JPMG 1H2PP 4ONTD 4LOSA 2QY0A 4WJG2 4YNXA 2ZYCA 3WSYA 4AYEA 1C1ZA 2B5ID 2XRDA 4LOTA 2XWBF 5FO8C 4HQLA 3GXEA 3VDJA 1OJWA 1H04P 1LY2A 1OJYA 4DJZA 1FBRA 2CKUA 5DN5A 2X2ZA 4JHSA 4PZ5A 2XQWC 2Y8RA 2EHFA 4J38B 2IZ3A 1O9AA 4AYIA 5HYPA 1QO6A 2MCZA 3L89M 2UWNA 1QUBA 1GKGA 2LOJA 3FGRA 1E5GA 3INBC 3CI0J 1TPMA 4B2SA 2MCYA 1OK1A 3KXVA 5HYUB 4MSLA 3R62A 4PO7A 3ERBA
chains in the Genus database with same CATH topology
2XRBA 2RL0A 1HFHA 1OK9A 2O39C 1G4GA 3OP8A 2JGXA 3EJHA 4FXGG 1HCCA 3SW0X 1OK3A 2RLQA 3KZJA 4AYDA 2EC3A 4ZH1D 5HZPB 1UOTP 3ZD1A 2YBYA 2A55A 1SRZA 1HFIA 1H03P 1VEXA 3R6BA 3VDLA 3ZD2A 1SZLA 1GKNA 1G4FA 3VDKA 4HQNA 2W81A 2RKZA 2RKYA 4MUCA 1TPNA 1Z92B 4A5WB 2IZ4A 2KRIA 1OJVA 5HYTB 4K12A 1QGBA 2JRAA 5I0QB 2CG7A 2W80A 3IX0A 3M7PA 1GHQB 4CSYA 2JGWA 1ZJKA 1MD7A 1PPQA 4HQOA 2ERJA 2WIIC 1U5MA 1OK2A 1Q3XA 1ELVA 3OXUD 2YRAA 4C16A 1VVDA 3O8EB 4IGDA 2XWJI 1CKLA 3RJ3D 1VVCA 3CALA 1H2QP 1E8BA 3OEDC 4B2RA 3IU3I 4KKDA 1GPZA 2BZMA 4AYMA 3MQLA 3GOVA 1MD8A 2KMSA 2RLPA 3TVJA 1TPGA 1SS2A 3NFPI 1LSLA 2V8EA 3T5OA 2CG6A 4F4OC 2G7IA 1E88A 1NWVA 3ZRZA 5JPMG 1H2PP 4ONTD 4LOSA 2QY0A 4WJG2 4YNXA 4AYEA 1C1ZA 2B5ID 2XRDA 4LOTA 2XWBF 5FO8C 4HQLA 3GXEA 3VDJA 1OJWA 1H04P 1LY2A 1OJYA 4DJZA 1FBRA 2CKUA 4JHSA 4PZ5A 2XQWC 2EHFA 4J38B 2IZ3A 1O9AA 4AYIA 5HYPA 1QO6A 2MCZA 3L89M 2UWNA 1QUBA 1GKGA 2LOJA 1E5GA 3INBC 1TPMA 4B2SA 2MCYA 1OK1A 3KXVA 5HYUB 3R62A 3ERBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XRB A;  2RL0 A;  1HFH A;  1OK9 A;  2O39 C;  1G4G A;  3OP8 A;  2JGX A;  3EJH A;  4FXG G;  1HCC A;  3SW0 X;  1OK3 A;  2RLQ A;  3KZJ A;  4AYD A;  2EC3 A;  4ZH1 D;  5HZP B;  1UOT P;  3ZD1 A;  2YBY A;  2A55 A;  1SRZ A;  1HFI A;  1H03 P;  1VEX A;  3R6B A;  3VDL A;  3ZD2 A;  1SZL A;  1GKN A;  1G4F A;  3VDK A;  4HQN A;  2W81 A;  2RKZ A;  2RKY A;  4MUC A;  1TPN A;  1Z92 B;  4A5W B;  2IZ4 A;  2KRI A;  1OJV A;  5HYT B;  4K12 A;  1QGB A;  2JRA A;  5I0Q B;  2CG7 A;  2W80 A;  3IX0 A;  3M7P A;  1GHQ B;  4CSY A;  2JGW A;  1ZJK A;  1MD7 A;  1PPQ A;  4HQO A;  2ERJ A;  2WII C;  1U5M A;  1OK2 A;  1Q3X A;  1ELV A;  3OXU D;  2YRA A;  4C16 A;  1VVD A;  3O8E B;  4IGD A;  2XWJ I;  1CKL A;  3RJ3 D;  1VVC A;  3CAL A;  1H2Q P;  1E8B A;  3OED C;  4B2R A;  3IU3 I;  4KKD A;  1GPZ A;  2BZM A;  4AYM A;  3MQL A;  3GOV A;  1MD8 A;  2KMS A;  2RLP A;  3TVJ A;  1TPG A;  1SS2 A;  3NFP I;  1LSL A;  2V8E A;  3T5O A;  2CG6 A;  4F4O C;  2G7I A;  1E88 A;  1NWV A;  3ZRZ A;  5JPM G;  1H2P P;  4ONT D;  4LOS A;  2QY0 A;  4WJG 2;  4YNX A;  4AYE A;  1C1Z A;  2B5I D;  2XRD A;  4LOT A;  2XWB F;  5FO8 C;  4HQL A;  3GXE A;  3VDJ A;  1OJW A;  1H04 P;  1LY2 A;  1OJY A;  4DJZ A;  1FBR A;  2CKU A;  4JHS A;  4PZ5 A;  2XQW C;  2EHF A;  4J38 B;  2IZ3 A;  1O9A A;  4AYI A;  5HYP A;  1QO6 A;  2MCZ A;  3L89 M;  2UWN A;  1QUB A;  1GKG A;  2LOJ A;  1E5G A;  3INB C;  1TPM A;  4B2S A;  2MCY A;  1OK1 A;  3KXV A;  5HYU B;  3R62 A;  3ERB A; 
#chains in the Genus database with same CATH topology
 2XRB A;  2RL0 A;  1HFH A;  1OK9 A;  2I2L A;  2O39 C;  1G4G A;  3OP8 A;  2JGX A;  3F6K A;  3EJH A;  4FXG G;  1HCC A;  3SW0 X;  3FGT A;  1OK3 A;  2RLQ A;  3KZJ A;  3VWO A;  4AYD A;  2EC3 A;  4ZH1 D;  4YIZ A;  5HZP B;  1UOT P;  3ZD1 A;  2YBY A;  2A55 A;  1SRZ A;  1HFI A;  1H03 P;  1VEX A;  3WSX A;  4BWC A;  3R6B A;  3VDL A;  3ZD2 A;  1SZL A;  1GKN A;  1G4F A;  3VDK A;  4HQN A;  2W81 A;  2RKZ A;  2RKY A;  4MUC A;  2Y8T A;  1TPN A;  1Z92 B;  4A5W B;  4APL A;  2IZ4 A;  3ZLD A;  2KRI A;  1OJV A;  3K3T A;  5HYT B;  4K12 A;  1QGB A;  2JRA A;  1RLH A;  2Y8S A;  5I0Q B;  2CG7 A;  2W80 A;  3IX0 A;  4N7E A;  3M7P A;  1GHQ B;  4CSY A;  2JGW A;  1ZJK A;  1MD7 A;  1PPQ A;  4HQO A;  2ERJ A;  2WII C;  1U5M A;  1OK2 A;  1Q3X A;  1ELV A;  3OXU D;  2YRA A;  4C16 A;  1VVD A;  3O8E B;  4IGD A;  2XWJ I;  1CKL A;  3RJ3 D;  1VVC A;  3CAL A;  1H2Q P;  1E8B A;  3OED C;  5DN4 A;  4B2R A;  3IU3 I;  4KKD A;  1GPZ A;  2BZM A;  4AYM A;  3MQL A;  3GOV A;  3ZLE A;  1MD8 A;  2KMS A;  2RLP A;  3TVJ A;  1TPG A;  1SS2 A;  3NFP I;  1LSL A;  2V8E A;  3T5O A;  2CG6 A;  4F4O C;  3NJA A;  2G7I A;  1E88 A;  1NWV A;  3ZRZ A;  5JPM G;  1H2P P;  4ONT D;  4LOS A;  2QY0 A;  4WJG 2;  4YNX A;  2ZYC A;  3WSY A;  4AYE A;  1C1Z A;  2B5I D;  2XRD A;  4LOT A;  2XWB F;  5FO8 C;  4HQL A;  3GXE A;  3VDJ A;  1OJW A;  1H04 P;  1LY2 A;  1OJY A;  4DJZ A;  1FBR A;  2CKU A;  5DN5 A;  2X2Z A;  4JHS A;  4PZ5 A;  2XQW C;  2Y8R A;  2EHF A;  4J38 B;  2IZ3 A;  1O9A A;  4AYI A;  5HYP A;  1QO6 A;  2MCZ A;  3L89 M;  2UWN A;  1QUB A;  1GKG A;  2LOJ A;  3FGR A;  1E5G A;  3INB C;  3CI0 J;  1TPM A;  4B2S A;  2MCY A;  1OK1 A;  3KXV A;  5HYU B;  4MSL A;  3R62 A;  4PO7 A;  3ERB A; 
#chains in the Genus database with same CATH homology
 2XRB A;  2RL0 A;  1HFH A;  1OK9 A;  2O39 C;  1G4G A;  3OP8 A;  2JGX A;  3EJH A;  4FXG G;  1HCC A;  3SW0 X;  1OK3 A;  2RLQ A;  3KZJ A;  4AYD A;  2EC3 A;  4ZH1 D;  5HZP B;  1UOT P;  3ZD1 A;  2YBY A;  2A55 A;  1SRZ A;  1HFI A;  1H03 P;  1VEX A;  3R6B A;  3VDL A;  3ZD2 A;  1SZL A;  1GKN A;  1G4F A;  3VDK A;  4HQN A;  2W81 A;  2RKZ A;  2RKY A;  4MUC A;  1TPN A;  1Z92 B;  4A5W B;  2IZ4 A;  2KRI A;  1OJV A;  5HYT B;  4K12 A;  1QGB A;  2JRA A;  5I0Q B;  2CG7 A;  2W80 A;  3IX0 A;  3M7P A;  1GHQ B;  4CSY A;  2JGW A;  1ZJK A;  1MD7 A;  1PPQ A;  4HQO A;  2ERJ A;  2WII C;  1U5M A;  1OK2 A;  1Q3X A;  1ELV A;  3OXU D;  2YRA A;  4C16 A;  1VVD A;  3O8E B;  4IGD A;  2XWJ I;  1CKL A;  3RJ3 D;  1VVC A;  3CAL A;  1H2Q P;  1E8B A;  3OED C;  4B2R A;  3IU3 I;  4KKD A;  1GPZ A;  2BZM A;  4AYM A;  3MQL A;  3GOV A;  1MD8 A;  2KMS A;  2RLP A;  3TVJ A;  1TPG A;  1SS2 A;  3NFP I;  1LSL A;  2V8E A;  3T5O A;  2CG6 A;  4F4O C;  2G7I A;  1E88 A;  1NWV A;  3ZRZ A;  5JPM G;  1H2P P;  4ONT D;  4LOS A;  2QY0 A;  4WJG 2;  4YNX A;  4AYE A;  1C1Z A;  2B5I D;  2XRD A;  4LOT A;  2XWB F;  5FO8 C;  4HQL A;  3GXE A;  3VDJ A;  1OJW A;  1H04 P;  1LY2 A;  1OJY A;  4DJZ A;  1FBR A;  2CKU A;  4JHS A;  4PZ5 A;  2XQW C;  2EHF A;  4J38 B;  2IZ3 A;  1O9A A;  4AYI A;  5HYP A;  1QO6 A;  2MCZ A;  3L89 M;  2UWN A;  1QUB A;  1GKG A;  2LOJ A;  1E5G A;  3INB C;  1TPM A;  4B2S A;  2MCY A;  1OK1 A;  3KXV A;  5HYU B;  3R62 A;  3ERB A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...