4A93L

Rna polymerase ii elongation complex containing a cpd lesion
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
46
structure length
46
Chain Sequence
ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 3
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2011-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4a93L00
4A3IL 3GTLL 3H3VM 3RZDL 5M5XL 3S1ML 3PO2L 4C3IL 3GTPL 1I50L 3S1RL 1I6HL 5C4JL 4Y7NL 5IP7L 2WB1P 1TWHL 2VUML 2E2IL 4A3ML 3HOXL 3S1NL 4BBRL 1Y1VL 5IYBL 4A3LL 2NVYL 4QIWP 1Y1WL 4A3BL 1TWFL 2E2JL 3GTJL 3M4OL 4A3DL 4AYBP 3I4ML 4Y52L 1WCML 5M5WL 3GTGL 2B63L 2R7ZL 5IYDL 3S2DL 4A3EL 4A3FL 5M3FL 3HOUL 3GTML 4BY1L 2WAQP 2NVXL 5FLML 3S14L 5IP9L 4C2M1 3H0GL 3S15L 2JA6L 2JA8L 4A3JL 3K7AL 2Y0SP 1R9TL 3S1QL 3HOZL 4BY7L 3S2HL 3RZOL 4A93L 4A3KL 3I4NL 1TWGL 2NVQL 3M3YL 4C3JL 3S17L 2R92L 4A3CL 2JA5L 2R93L 5IYCL 3HOVL 3FKIL 1K83L 4BBSL 5C44L 2NVTL 5C4XL 2PMZP 2JA7L 1TWAL 5FJ8L 4BXXL 4C3HL 5M3ML 3GTKL 3HKZP 3CQZL 2YU9L 3GTQL 5C3EL 5M5YL 3GTOL 4A3GL 1I3QL 3HOYL 1TWCL 2E2HL 3S16L 4X6AL 1SFOL 3HOWL 3PO3L
chains in the Genus database with same CATH superfamily
2C6AA 1BE7A 2LCQA 2AQCA 3P8BA 8RXNA 4AI2A 3J7Z1 4Y7NL 2H12A 5AN9H 2E2IL 3S1NL 2XJQA 4TVMA 1YK5A 4QIWP 5H1Sc 5MFPA 1LKPA 2V0FA 1QQTA 3GTJL 3M4OL 4A3DL 2AYJA 2XJSA 4AYBP 5MF6A 1T9OA 1WCML 4GS7D 1PZXA 1F4LA 1SMWA 3KYWA 1FHHA 4BY1L 5MLC3 2AUSB 1RDGA 5FLML 4JAFA 3S15L 1S30A 5MFZA 5AI3A 1PFWA 4BY7L 2JI2A 4E6YA 1TWGL 1PFYA 4AHWA 1IU5A 1R0JA 1NNQA 4XGHA 3S17L 4A3CL 3B08B 2PVXA 3PKIA 3J7Y1 3FKIL 2NVTL 1R0GA 4AR6A 2PMZP 2JA7L 1TWAL 5FJ8L 3GTKL 1C09A 2YU9L 5C3EL 1NXGA 3HOYL 2QL0A 1TWCL 4POGA 3QQCE 3GTLL 3LWPB 4YWLA 4C3IL 5EIOC 3GTPL 3MPSA 1I6HL 5DM61 5IP7L 1TWHL 4A3ML 1RYTA 3RZTA 2M4YA 1R0FA 1YUZA 1B2OA 2J9UB 2XJPA 4JAEA 1SMMA 1Y1VL 2XJVA 4A3LL 4AR3A 1TWFL 2E2JL 2M6OA 3HAXC 2A69D 1ZRPA 4Y52L 2B63L 1BFYA 1LTLA 2KN9A 3PIO1 1T9PA 2JI3A 3GTML 2EY4E 3P2AA 1VZHA 5GAGc 1P7PA 5IP9L 2MS3A 1IROA 2GMGA 2JA6L 1S2ZA 3K35A 5GAEc 5JVG1 1B13A 3LWOB 4JAGA 3S2HL 3RZOL 3FDJA 1R0HA 1BRFA 3PWFA 4C3JL 1IU6A 1K83L 1OWBA 5EINC 2APOB 1QCVA 4AI3A 3WWNB 4LHNA 2B5ID 3PZAA 4BXXL 3HKZP 1ODHA 3GTOL 1PFUA 3LPEB 3QVDA 3MSUA 3HOWL 4BBSL 3PO3L 4A3IL 3H3VM 3RZDL 5M5XL 2A6ED 3S1ML 3PO2L 1JYBA 1T9QA 4UY81 1BQ8A 5GADc 5C4JL 2C6BA 2CKAA 2O5JD 2M6PA 5MGNA 5JVH1 1E8JA 4BBRL 2CR8A 3KYXA 4G6BA 1RYQA 2NVYL 4TPUA 1BQ9A 4A3BL 2CKCA 3RYGA 7RXNA 1VZIA 1B2JA 3LNLA 3KYYA 5M5WL 6RXNA 3HJWB 1CAAA 2A68D 5IYDL 4A3FL 1QYBA 1IW7D 2WAQP 2NVXL 3KYUA 3PKJA 1SMUA 1WJVA 2NYDA 3WWLA 2ZIXA 4A3JL 1LKOA 2M4VA 2Y0SP 3K7AL 1YK4A 3HOZL 1LKMA 4POFA 4A3KL 4YWMA 3I4NL 1Z92B 4AHYA 2NVQL 1VZGA 1DX8A 2R92L 3LWQB 4AR5A 2JA5L 5IYCL 3HJYB 2PVEA 5RXNA 5M3ML 3A44A 3CQZL 4JADA 4AHZA 4U671 1I3QL 4AI1A 5AI2A 3S16L 1SFOL 1R0IA 2Z3RB 2PYAA 2HR5A 1OWCA 2PSMC 1RWDA 1S24A 4ME3A 2K2DA 2PPTA 5K2ME 1YV1A 1YUXA 1FHMA 3IU3I 4LHLA 1I50L 3S1RL 2RFKB 2WB1P 3JR7A 2VUML 2L0ZA 3H97A 3KYVA 2ERJA 3HOXL 3B0AB 2Z3QB 1DVBA 4V196 3H9CA 2KKDA 3VPBE 5IYBL 3LWVB 1Y1WL 1PFVA 5GAHc 2RDVA 2XJTA 3I4ML 4AI0A 3GTGL 2R7ZL 3S2DL 4A3EL 5M3FL 3HOUL 2XJUA 3S14L 4ZN3B 4C2M1 3H0GL 3ZG6A 2A6HD 3MQKB 2JA8L 2DSXA 4B8CD 1R9TL 3S1QL 5DM71 1H7VA 2V3BB 3SS2A 3RZ6A 1VCXA 4A93L 4K9FA 5IY0A 3M3YL 3H99A 4WFN1 3PL5A 1CADA 2R93L 2XJRA 3HOVL 4AHXA 1RB9A 1RDVA 5C44L 2ERSA 4AR4A 2HVYC 5C4XL 3H9BA 3NFPI 4C3HL 1NXEA 4XXBB 3GTQL 5M5YL 4ZN1B 3LWRB 1B71A 4A3GL 4RXNA 2VL6A 2V0EA 2E2HL 2BE5D 4X6AL 3PIP1 2JI1A 1IRNA
chains in the Genus database with same CATH topology
4A3IL 3GTLL 3H3VM 3RZDL 5M5XL 3S1ML 3PO2L 4C3IL 3GTPL 1I50L 3S1RL 1I6HL 5C4JL 4Y7NL 5IP7L 2WB1P 1TWHL 2VUML 2E2IL 4A3ML 3HOXL 3S1NL 4BBRL 1Y1VL 5IYBL 4A3LL 2NVYL 4QIWP 1Y1WL 4A3BL 1TWFL 2E2JL 3GTJL 3M4OL 4A3DL 4AYBP 3I4ML 4Y52L 1WCML 5M5WL 3GTGL 2B63L 2R7ZL 5IYDL 3S2DL 4A3EL 4A3FL 5M3FL 3HOUL 3GTML 4BY1L 2WAQP 2NVXL 5FLML 3S14L 5IP9L 4C2M1 3H0GL 3S15L 2JA6L 2JA8L 4A3JL 3K7AL 2Y0SP 1R9TL 3S1QL 3HOZL 4BY7L 3S2HL 3RZOL 4A93L 4A3KL 3I4NL 1TWGL 2NVQL 3M3YL 4C3JL 3S17L 2R92L 4A3CL 2JA5L 2R93L 5IYCL 3HOVL 3FKIL 1K83L 4BBSL 5C44L 2NVTL 5C4XL 2PMZP 2JA7L 1TWAL 5FJ8L 4BXXL 4C3HL 5M3ML 3GTKL 3HKZP 3CQZL 2YU9L 3GTQL 5C3EL 5M5YL 3GTOL 4A3GL 1I3QL 3HOYL 1TWCL 2E2HL 3S16L 4X6AL 1SFOL 3HOWL 3PO3L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3I L;  3GTL L;  3H3V M;  3RZD L;  5M5X L;  3S1M L;  3PO2 L;  4C3I L;  3GTP L;  1I50 L;  3S1R L;  1I6H L;  5C4J L;  4Y7N L;  5IP7 L;  2WB1 P;  1TWH L;  2VUM L;  2E2I L;  4A3M L;  3HOX L;  3S1N L;  4BBR L;  1Y1V L;  5IYB L;  4A3L L;  2NVY L;  4QIW P;  1Y1W L;  4A3B L;  1TWF L;  2E2J L;  3GTJ L;  3M4O L;  4A3D L;  4AYB P;  3I4M L;  4Y52 L;  1WCM L;  5M5W L;  3GTG L;  2B63 L;  2R7Z L;  5IYD L;  3S2D L;  4A3E L;  4A3F L;  5M3F L;  3HOU L;  3GTM L;  4BY1 L;  2WAQ P;  2NVX L;  5FLM L;  3S14 L;  5IP9 L;  4C2M 1;  3H0G L;  3S15 L;  2JA6 L;  2JA8 L;  4A3J L;  3K7A L;  2Y0S P;  1R9T L;  3S1Q L;  3HOZ L;  4BY7 L;  3S2H L;  3RZO L;  4A93 L;  4A3K L;  3I4N L;  1TWG L;  2NVQ L;  3M3Y L;  4C3J L;  3S17 L;  2R92 L;  4A3C L;  2JA5 L;  2R93 L;  5IYC L;  3HOV L;  3FKI L;  1K83 L;  4BBS L;  5C44 L;  2NVT L;  5C4X L;  2PMZ P;  2JA7 L;  1TWA L;  5FJ8 L;  4BXX L;  4C3H L;  5M3M L;  3GTK L;  3HKZ P;  3CQZ L;  2YU9 L;  3GTQ L;  5C3E L;  5M5Y L;  3GTO L;  4A3G L;  1I3Q L;  3HOY L;  1TWC L;  2E2H L;  3S16 L;  4X6A L;  1SFO L;  3HOW L;  3PO3 L; 
#chains in the Genus database with same CATH topology
 2C6A A;  1BE7 A;  2LCQ A;  2AQC A;  3P8B A;  8RXN A;  4AI2 A;  3J7Z 1;  4Y7N L;  2H12 A;  5AN9 H;  2E2I L;  3S1N L;  2XJQ A;  4TVM A;  1YK5 A;  4QIW P;  5H1S c;  5MFP A;  1LKP A;  2V0F A;  1QQT A;  3GTJ L;  3M4O L;  4A3D L;  2AYJ A;  2XJS A;  4AYB P;  5MF6 A;  1T9O A;  1WCM L;  4GS7 D;  1PZX A;  1F4L A;  1SMW A;  3KYW A;  1FHH A;  4BY1 L;  5MLC 3;  2AUS B;  1RDG A;  5FLM L;  4JAF A;  3S15 L;  1S30 A;  5MFZ A;  5AI3 A;  1PFW A;  4BY7 L;  2JI2 A;  4E6Y A;  1TWG L;  1PFY A;  4AHW A;  1IU5 A;  1R0J A;  1NNQ A;  4XGH A;  3S17 L;  4A3C L;  3B08 B;  2PVX A;  3PKI A;  3J7Y 1;  3FKI L;  2NVT L;  1R0G A;  4AR6 A;  2PMZ P;  2JA7 L;  1TWA L;  5FJ8 L;  3GTK L;  1C09 A;  2YU9 L;  5C3E L;  1NXG A;  3HOY L;  2QL0 A;  1TWC L;  4POG A;  3QQC E;  3GTL L;  3LWP B;  4YWL A;  4C3I L;  5EIO C;  3GTP L;  3MPS A;  1I6H L;  5DM6 1;  5IP7 L;  1TWH L;  4A3M L;  1RYT A;  3RZT A;  2M4Y A;  1R0F A;  1YUZ A;  1B2O A;  2J9U B;  2XJP A;  4JAE A;  1SMM A;  1Y1V L;  2XJV A;  4A3L L;  4AR3 A;  1TWF L;  2E2J L;  2M6O A;  3HAX C;  2A69 D;  1ZRP A;  4Y52 L;  2B63 L;  1BFY A;  1LTL A;  2KN9 A;  3PIO 1;  1T9P A;  2JI3 A;  3GTM L;  2EY4 E;  3P2A A;  1VZH A;  5GAG c;  1P7P A;  5IP9 L;  2MS3 A;  1IRO A;  2GMG A;  2JA6 L;  1S2Z A;  3K35 A;  5GAE c;  5JVG 1;  1B13 A;  3LWO B;  4JAG A;  3S2H L;  3RZO L;  3FDJ A;  1R0H A;  1BRF A;  3PWF A;  4C3J L;  1IU6 A;  1K83 L;  1OWB A;  5EIN C;  2APO B;  1QCV A;  4AI3 A;  3WWN B;  4LHN A;  2B5I D;  3PZA A;  4BXX L;  3HKZ P;  1ODH A;  3GTO L;  1PFU A;  3LPE B;  3QVD A;  3MSU A;  3HOW L;  4BBS L;  3PO3 L;  4A3I L;  3H3V M;  3RZD L;  5M5X L;  2A6E D;  3S1M L;  3PO2 L;  1JYB A;  1T9Q A;  4UY8 1;  1BQ8 A;  5GAD c;  5C4J L;  2C6B A;  2CKA A;  2O5J D;  2M6P A;  5MGN A;  5JVH 1;  1E8J A;  4BBR L;  2CR8 A;  3KYX A;  4G6B A;  1RYQ A;  2NVY L;  4TPU A;  1BQ9 A;  4A3B L;  2CKC A;  3RYG A;  7RXN A;  1VZI A;  1B2J A;  3LNL A;  3KYY A;  5M5W L;  6RXN A;  3HJW B;  1CAA A;  2A68 D;  5IYD L;  4A3F L;  1QYB A;  1IW7 D;  2WAQ P;  2NVX L;  3KYU A;  3PKJ A;  1SMU A;  1WJV A;  2NYD A;  3WWL A;  2ZIX A;  4A3J L;  1LKO A;  2M4V A;  2Y0S P;  3K7A L;  1YK4 A;  3HOZ L;  1LKM A;  4POF A;  4A3K L;  4YWM A;  3I4N L;  1Z92 B;  4AHY A;  2NVQ L;  1VZG A;  1DX8 A;  2R92 L;  3LWQ B;  4AR5 A;  2JA5 L;  5IYC L;  3HJY B;  2PVE A;  5RXN A;  5M3M L;  3A44 A;  3CQZ L;  4JAD A;  4AHZ A;  4U67 1;  1I3Q L;  4AI1 A;  5AI2 A;  3S16 L;  1SFO L;  1R0I A;  2Z3R B;  2PYA A;  2HR5 A;  1OWC A;  2PSM C;  1RWD A;  1S24 A;  4ME3 A;  2K2D A;  2PPT A;  5K2M E;  1YV1 A;  1YUX A;  1FHM A;  3IU3 I;  4LHL A;  1I50 L;  3S1R L;  2RFK B;  2WB1 P;  3JR7 A;  2VUM L;  2L0Z A;  3H97 A;  3KYV A;  2ERJ A;  3HOX L;  3B0A B;  2Z3Q B;  1DVB A;  4V19 6;  3H9C A;  2KKD A;  3VPB E;  5IYB L;  3LWV B;  1Y1W L;  1PFV A;  5GAH c;  2RDV A;  2XJT A;  3I4M L;  4AI0 A;  3GTG L;  2R7Z L;  3S2D L;  4A3E L;  5M3F L;  3HOU L;  2XJU A;  3S14 L;  4ZN3 B;  4C2M 1;  3H0G L;  3ZG6 A;  2A6H D;  3MQK B;  2JA8 L;  2DSX A;  4B8C D;  1R9T L;  3S1Q L;  5DM7 1;  1H7V A;  2V3B B;  3SS2 A;  3RZ6 A;  1VCX A;  4A93 L;  4K9F A;  5IY0 A;  3M3Y L;  3H99 A;  4WFN 1;  3PL5 A;  1CAD A;  2R93 L;  2XJR A;  3HOV L;  4AHX A;  1RB9 A;  1RDV A;  5C44 L;  2ERS A;  4AR4 A;  2HVY C;  5C4X L;  3H9B A;  3NFP I;  4C3H L;  1NXE A;  4XXB B;  3GTQ L;  5M5Y L;  4ZN1 B;  3LWR B;  1B71 A;  4A3G L;  4RXN A;  2VL6 A;  2V0E A;  2E2H L;  2BE5 D;  4X6A L;  3PIP 1;  2JI1 A;  1IRN A; 
#chains in the Genus database with same CATH homology
 4A3I L;  3GTL L;  3H3V M;  3RZD L;  5M5X L;  3S1M L;  3PO2 L;  4C3I L;  3GTP L;  1I50 L;  3S1R L;  1I6H L;  5C4J L;  4Y7N L;  5IP7 L;  2WB1 P;  1TWH L;  2VUM L;  2E2I L;  4A3M L;  3HOX L;  3S1N L;  4BBR L;  1Y1V L;  5IYB L;  4A3L L;  2NVY L;  4QIW P;  1Y1W L;  4A3B L;  1TWF L;  2E2J L;  3GTJ L;  3M4O L;  4A3D L;  4AYB P;  3I4M L;  4Y52 L;  1WCM L;  5M5W L;  3GTG L;  2B63 L;  2R7Z L;  5IYD L;  3S2D L;  4A3E L;  4A3F L;  5M3F L;  3HOU L;  3GTM L;  4BY1 L;  2WAQ P;  2NVX L;  5FLM L;  3S14 L;  5IP9 L;  4C2M 1;  3H0G L;  3S15 L;  2JA6 L;  2JA8 L;  4A3J L;  3K7A L;  2Y0S P;  1R9T L;  3S1Q L;  3HOZ L;  4BY7 L;  3S2H L;  3RZO L;  4A93 L;  4A3K L;  3I4N L;  1TWG L;  2NVQ L;  3M3Y L;  4C3J L;  3S17 L;  2R92 L;  4A3C L;  2JA5 L;  2R93 L;  5IYC L;  3HOV L;  3FKI L;  1K83 L;  4BBS L;  5C44 L;  2NVT L;  5C4X L;  2PMZ P;  2JA7 L;  1TWA L;  5FJ8 L;  4BXX L;  4C3H L;  5M3M L;  3GTK L;  3HKZ P;  3CQZ L;  2YU9 L;  3GTQ L;  5C3E L;  5M5Y L;  3GTO L;  4A3G L;  1I3Q L;  3HOY L;  1TWC L;  2E2H L;  3S16 L;  4X6A L;  1SFO L;  3HOW L;  3PO3 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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