4AH4A

Crystal structure of fucose binding lectin from aspergillus fumigatus (afl) in complex with bga oligosaccharide.
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
314
structure length
313
Chain Sequence
STPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGTEKNVIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGGLGGAKFQVAPYSCIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKEGTNLGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGWYPDLVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVWDHGKGYHDKGTITPVIQGSEVAIISWGSFANNGPDLRLYFQNGTYISAVSEWVWNRAHGSQLGRSALPPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Aspergillus fumigatus
molecule keywords FUCOSE-SPECIFIC LECTIN FLEA
total genus 82
structure length 313
sequence length 314
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07938 Fungal_lectin Fungal fucose-specific lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.70 Mainly Beta 6 Propeller Neuraminidase Fucose-specific lectin 4ah4A00
4D52C 4D52A 1IUBA 5EO8A 4C1YB 4D52B 5EO7A 4AGTA 4C1YA 4CSDA 5H47A 1IUCA 4AGIA 4D4UA 4UOUA 4AHAA 4AH4A 1OFZA
chains in the Genus database with same CATH superfamily
3TIAA 4FOWA 3DR2A 4Q1UA 2P4OA 1IVGA 4MWQA 4NC5A 2SIMA 1SO7A 2IAOA 2IAQA 4K1HA 4UF7A 4HHQA 5FWWA 1C5KA 4X49A 3P5BL 5GX5A 5HUGA 1NNCA 2ZW9A 3Q6KA 4MWUA 1MS5A 2F0ZA 2GHSA 4D4UA 2XCYA 2QWCA 2XZJA 2DYHA 3SLIA 4NCSA 4IN4A 2IARA 2Z32A 2XN4A 4MWVA 1NNBA 1EUUA 3JU4A 1QLGA 4FJ6A 4QN3A 4XMBA 3Q6PA 4GN8A 5GTQA 1V0FA 4MJVA 1DIMA 4N1BA 2FP8A 4K1KA 1Q7FA 3TC9A 3OPZA 1CRUA 1EUTA 1POOA 4HZWA 3A72A 3V64C 3S8ZA 4B7QA 2VSKA 2FPCA 4FOQA 5B2DA 2IASA 1IVEA 4GNAA 4I00A 4QN5A 2G8SA 1NCBN 2ZB5A 2ISMA 2GVXA 3LI5A 2QWBA 4R40A 5B2CA 1INYA 1EURA 3WWAA 2VAQA 3HLHA 4FPFA 5HUKA 3GVLA 4G3NA 1INHA 2X9MA 3L6VA 2V91A 4L7DA 4C1YA 5HUMA 2IAXA 4QN7A 2F29A 2HTVA 2VK7A 2IAUA 7NN9A 3HRPA 5F9TA 3KGGA 3I1CA 3D11A 3HLIA 3TI4A 1W0OA 1USRA 2GVVA 4DGRA 5EX7A 1VCUA 1U6DX 2QWHA 4GZTA 4GZWA 5FNSA 3E5ZA 4ZLRA 2F25A 3S2KA 1NSCA 4YW4A 4GNBA 1MZ6A 2FLUX 5FZJA 4NN9A 4XIKA 2HT5A 5GX3A 1MWEA 4A0PA 2ZWAA 3Q6TA 2FHRA 2POOA 1Z4WA 1IJQA 2VW0A 3TI6A 4ZY3A 3TI8A 4MZEA 1S18A 1V3DA 3INBA 4KS5A 2GVWA 4FPEA 2IAVA 4FOYA 1WCQA 1E1AA 4FQ4A 4GN7A 4K3YA 4D8SA 4FPJA 4Q6KA 3S94A 1F8BA 4YZ2A 1INWA 5FNRA 1NN2A 2IVZA 2VW1A 1N6FA 4PWZA 3ALWA 4CPYA 3H72A 4HHOA 1A4GA 1NMBN 4XJ9A 1NSDA 2VVZA 4IMBA 1N1SA 4IFJA 3A71A 1MR5A 4YW5A 3SRGA 1INXA 3SALA 1F8DA 1SLLA 4YW1A 3WDZA 1C9UA 4X4AA 1MS8A 1NMCA 1CRZA 1V3BA 1INGA 4FVKA 4D52B 5FNUA 4FP3A 3D12A 4XIOA 1F8EA 4FPYA 4GEZA 1XOEA 3SILA 3KYAA 2QE8A 3A9GA 1USXA 2YDTA 4IQKA 3SREA 2VK6A 3CL0A 2F10A 4MWRA 2QWFA 4L7CA 1Z4ZA 3CKZA 3GVKA 4XJ8A 2VPJA 1W0PA 2F24A 1PJXA 1WP5A 4XOGA 4CPMA 4D52C 2GVUA 3GVJA 1L7GA 1NCAN 3O4PA 1B9SA 3II7A 4FPLA 2QWAA 4B7JA 5GX2A 2JKBA 1IVCA 2C4LA 5FNQA 3AMRA 4C1YB 4FPCA 4FZHA 1W8OA 1ZI0A 4ZGCA 4XILA 5GX4A 4XJRA 1V2IA 4WA4A 5D9CA 3K37A 1F8CA 4IFNX 1NCDN 1A4QA 2HTWA 2A75A 4WA5A 1Z4YA 3A9HA 4GDJA 3S8VA 2YDPA 4KS2A 4O5TA 4QNPA 2VWDA 4FOVA 3LI3A 4CPLA 4XJWA 4JF7A 4XJUA 1VCJA 4K1IA 4XJQA 2W38A 4K1JA 4SLIA 2HT7A 4MWWA 4XE9A 3B7EA 5NN9A 3TICA 2HTYA 4XHXA 5JYYA 1MZ5A 4AHAA 4YW2A 1X2JA 4YZ5A 2HTQA 4GB1A 4CPOA 4MWLA 1OFZA 4J9TA 4MX0A 1CVMA 4CPNA 5EO7A 4IYGA 2IATA 3WN7A 3SOQA 2BATA 2F26A 1N1VA 1NCCN 4GZXA 4H52A 4YZ3A 4QN4A 4WEGA 1N6DA 4HZYA 4WEFA 2F11A 2HU4A 4HW6A 2W5NA 3ADEA 4IFLX 1IVBA 4BBWA 4FPKA 1E8VA 3LI4A 4X6KA 1Z4XA 3U0SA 4XMIA 1W21A 2QWKA 5EO8A 2YA7A 3FVZA 2F27A 1V3CA 4XJZA 1DILA 1NNAA 3G4EA 3ZGCA 5F72C 2ZB6A 1S1DA 4MJUA 1RWIA 2BZDA 4GZQA 3V65B 4HZVA 1A14N 4HIZA 1V0ZA 1X2RA 5D9BA 4GJTA 4YW3A 2FPBA 4GZOA 3V1SA 3SOBB 2QWGA 3ZGDA 3T1EA 1IUBA 3O9KA 4XJAA 2F28A 1V04A 2QWDA 6NN9A 2AGSA 2DG0A 3NSSA 5FZNA 4HZXA 2H2UA 1E8TA 2DSOA 2YA6A 1W20A 4CSDA 2WOZA 2RKCA 4XYXA 4WA3A 3SOVA 3W09A 1B9TA 3CL2A 2VK5A 2HQSA 4M4NA 3UC1A 4AH4A 4UOUA 4H53A 2C4AA 5HUNA 2W8BA 2HT8A 1N1YA 2H2NA 2QWJA 4KS1A 1NMAN 1L7FA 3K3AA 5HX0A 3ALXA 2AH2A 4M3MA 2IAPA 3FW0A 1BJIA 3O9JA 2YA4A 1INVA 4GNCA 3H71A 1IVFA 4FPOB 4FPHA 1NSBA 1XOGA 3H73A 4GDIA 4MC7A 4DG6A 1MS1A 1INFA 4MWXA 4D52A 2F13A 2W20A 4KS3A 1MS9A 3H6JA 1S0JA 1MS3A 4AGTA 2OJHA 3VNGA 1Z50A 2HTUA 2HTRA 5FNTA 4B7MA 1CQ1A 2QWIA 4CPZA 1WCSA 3NN9A 1E8UA 2HU0A 1S0IA 1B9VA 1N1TA 1ZGKA 4XMAA 4XHBA 4ASCA 2BERA 1K32A 4HZZA 4CHBA 1W8NA 2AEQA 3TIBA 1N6EA 2B8HA 2CMLA 2VW2A 4MZAA 1MS0A 3BEQA 4YY8A 2YA5A 2DG1A 5D9DA 4QN6A 3K36A 4GZSA 1W1XA 4KS4A 1EUSA 3WW9A 2AEPA 1V0EA 2VSMA 4AGIA 2XZIA 2F12A 3TI3A 4X47A 4YZ1A 1N7DA 3K39A 1IVDA 3PJQA 2QWEA 1QBIA 5M1ZA 4GN9A 4GZPA 4JMLA 2IAWA 4CH9A 1L7HA 5H47A 1V3EA 2ZZKA 2YA8A 3NO0A 5GX1A 4FP2A 1MS4A 3BYCA 2W5OA 5CGJA 3IAXA 4M4VA 4L7BA 4B7RA 1KITA 2FP9A 1H6LA 4YZ4A 3B69A 3DASA 1RWLA 4MWJA 4M4UA 3TI5A 1IUCA 3VNHA 3K38A 2W8BB 3G4HA 4FPGA 1NPEA 1SNTA 2BF6A 2XZKA 3SANA 4MWYA 2SLIA 1SLIA 2SILA 1SUUA 3AMSA 4B7NA 4O5SA 1Z4VA 3CYEA
chains in the Genus database with same CATH topology
4D52C 4D52A 1IUBA 5EO8A 4C1YB 4D52B 5EO7A 4AGTA 4C1YA 4CSDA 5H47A 1IUCA 4AGIA 4D4UA 4UOUA 4AHAA 4AH4A 1OFZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D52 C;  4D52 A;  1IUB A;  5EO8 A;  4C1Y B;  4D52 B;  5EO7 A;  4AGT A;  4C1Y A;  4CSD A;  5H47 A;  1IUC A;  4AGI A;  4D4U A;  4UOU A;  4AHA A;  4AH4 A;  1OFZ A; 
#chains in the Genus database with same CATH topology
 3TIA A;  4FOW A;  3DR2 A;  4Q1U A;  2P4O A;  1IVG A;  4MWQ A;  4NC5 A;  2SIM A;  1SO7 A;  2IAO A;  2IAQ A;  4K1H A;  4UF7 A;  4HHQ A;  5FWW A;  1C5K A;  4X49 A;  3P5B L;  5GX5 A;  5HUG A;  1NNC A;  2ZW9 A;  3Q6K A;  4MWU A;  1MS5 A;  2F0Z A;  2GHS A;  4D4U A;  2XCY A;  2QWC A;  2XZJ A;  2DYH A;  3SLI A;  4NCS A;  4IN4 A;  2IAR A;  2Z32 A;  2XN4 A;  4MWV A;  1NNB A;  1EUU A;  3JU4 A;  1QLG A;  4FJ6 A;  4QN3 A;  4XMB A;  3Q6P A;  4GN8 A;  5GTQ A;  1V0F A;  4MJV A;  1DIM A;  4N1B A;  2FP8 A;  4K1K A;  1Q7F A;  3TC9 A;  3OPZ A;  1CRU A;  1EUT A;  1POO A;  4HZW A;  3A72 A;  3V64 C;  3S8Z A;  4B7Q A;  2VSK A;  2FPC A;  4FOQ A;  5B2D A;  2IAS A;  1IVE A;  4GNA A;  4I00 A;  4QN5 A;  2G8S A;  1NCB N;  2ZB5 A;  2ISM A;  2GVX A;  3LI5 A;  2QWB A;  4R40 A;  5B2C A;  1INY A;  1EUR A;  3WWA A;  2VAQ A;  3HLH A;  4FPF A;  5HUK A;  3GVL A;  4G3N A;  1INH A;  2X9M A;  3L6V A;  2V91 A;  4L7D A;  4C1Y A;  5HUM A;  2IAX A;  4QN7 A;  2F29 A;  2HTV A;  2VK7 A;  2IAU A;  7NN9 A;  3HRP A;  5F9T A;  3KGG A;  3I1C A;  3D11 A;  3HLI A;  3TI4 A;  1W0O A;  1USR A;  2GVV A;  4DGR A;  5EX7 A;  1VCU A;  1U6D X;  2QWH A;  4GZT A;  4GZW A;  5FNS A;  3E5Z A;  4ZLR A;  2F25 A;  3S2K A;  1NSC A;  4YW4 A;  4GNB A;  1MZ6 A;  2FLU X;  5FZJ A;  4NN9 A;  4XIK A;  2HT5 A;  5GX3 A;  1MWE A;  4A0P A;  2ZWA A;  3Q6T A;  2FHR A;  2POO A;  1Z4W A;  1IJQ A;  2VW0 A;  3TI6 A;  4ZY3 A;  3TI8 A;  4MZE A;  1S18 A;  1V3D A;  3INB A;  4KS5 A;  2GVW A;  4FPE A;  2IAV A;  4FOY A;  1WCQ A;  1E1A A;  4FQ4 A;  4GN7 A;  4K3Y A;  4D8S A;  4FPJ A;  4Q6K A;  3S94 A;  1F8B A;  4YZ2 A;  1INW A;  5FNR A;  1NN2 A;  2IVZ A;  2VW1 A;  1N6F A;  4PWZ A;  3ALW A;  4CPY A;  3H72 A;  4HHO A;  1A4G A;  1NMB N;  4XJ9 A;  1NSD A;  2VVZ A;  4IMB A;  1N1S A;  4IFJ A;  3A71 A;  1MR5 A;  4YW5 A;  3SRG A;  1INX A;  3SAL A;  1F8D A;  1SLL A;  4YW1 A;  3WDZ A;  1C9U A;  4X4A A;  1MS8 A;  1NMC A;  1CRZ A;  1V3B A;  1ING A;  4FVK A;  4D52 B;  5FNU A;  4FP3 A;  3D12 A;  4XIO A;  1F8E A;  4FPY A;  4GEZ A;  1XOE A;  3SIL A;  3KYA A;  2QE8 A;  3A9G A;  1USX A;  2YDT A;  4IQK A;  3SRE A;  2VK6 A;  3CL0 A;  2F10 A;  4MWR A;  2QWF A;  4L7C A;  1Z4Z A;  3CKZ A;  3GVK A;  4XJ8 A;  2VPJ A;  1W0P A;  2F24 A;  1PJX A;  1WP5 A;  4XOG A;  4CPM A;  4D52 C;  2GVU A;  3GVJ A;  1L7G A;  1NCA N;  3O4P A;  1B9S A;  3II7 A;  4FPL A;  2QWA A;  4B7J A;  5GX2 A;  2JKB A;  1IVC A;  2C4L A;  5FNQ A;  3AMR A;  4C1Y B;  4FPC A;  4FZH A;  1W8O A;  1ZI0 A;  4ZGC A;  4XIL A;  5GX4 A;  4XJR A;  1V2I A;  4WA4 A;  5D9C A;  3K37 A;  1F8C A;  4IFN X;  1NCD N;  1A4Q A;  2HTW A;  2A75 A;  4WA5 A;  1Z4Y A;  3A9H A;  4GDJ A;  3S8V A;  2YDP A;  4KS2 A;  4O5T A;  4QNP A;  2VWD A;  4FOV A;  3LI3 A;  4CPL A;  4XJW A;  4JF7 A;  4XJU A;  1VCJ A;  4K1I A;  4XJQ A;  2W38 A;  4K1J A;  4SLI A;  2HT7 A;  4MWW A;  4XE9 A;  3B7E A;  5NN9 A;  3TIC A;  2HTY A;  4XHX A;  5JYY A;  1MZ5 A;  4AHA A;  4YW2 A;  1X2J A;  4YZ5 A;  2HTQ A;  4GB1 A;  4CPO A;  4MWL A;  1OFZ A;  4J9T A;  4MX0 A;  1CVM A;  4CPN A;  5EO7 A;  4IYG A;  2IAT A;  3WN7 A;  3SOQ A;  2BAT A;  2F26 A;  1N1V A;  1NCC N;  4GZX A;  4H52 A;  4YZ3 A;  4QN4 A;  4WEG A;  1N6D A;  4HZY A;  4WEF A;  2F11 A;  2HU4 A;  4HW6 A;  2W5N A;  3ADE A;  4IFL X;  1IVB A;  4BBW A;  4FPK A;  1E8V A;  3LI4 A;  4X6K A;  1Z4X A;  3U0S A;  4XMI A;  1W21 A;  2QWK A;  5EO8 A;  2YA7 A;  3FVZ A;  2F27 A;  1V3C A;  4XJZ A;  1DIL A;  1NNA A;  3G4E A;  3ZGC A;  5F72 C;  2ZB6 A;  1S1D A;  4MJU A;  1RWI A;  2BZD A;  4GZQ A;  3V65 B;  4HZV A;  1A14 N;  4HIZ A;  1V0Z A;  1X2R A;  5D9B A;  4GJT A;  4YW3 A;  2FPB A;  4GZO A;  3V1S A;  3SOB B;  2QWG A;  3ZGD A;  3T1E A;  1IUB A;  3O9K A;  4XJA A;  2F28 A;  1V04 A;  2QWD A;  6NN9 A;  2AGS A;  2DG0 A;  3NSS A;  5FZN A;  4HZX A;  2H2U A;  1E8T A;  2DSO A;  2YA6 A;  1W20 A;  4CSD A;  2WOZ A;  2RKC A;  4XYX A;  4WA3 A;  3SOV A;  3W09 A;  1B9T A;  3CL2 A;  2VK5 A;  2HQS A;  4M4N A;  3UC1 A;  4AH4 A;  4UOU A;  4H53 A;  2C4A A;  5HUN A;  2W8B A;  2HT8 A;  1N1Y A;  2H2N A;  2QWJ A;  4KS1 A;  1NMA N;  1L7F A;  3K3A A;  5HX0 A;  3ALX A;  2AH2 A;  4M3M A;  2IAP A;  3FW0 A;  1BJI A;  3O9J A;  2YA4 A;  1INV A;  4GNC A;  3H71 A;  1IVF A;  4FPO B;  4FPH A;  1NSB A;  1XOG A;  3H73 A;  4GDI A;  4MC7 A;  4DG6 A;  1MS1 A;  1INF A;  4MWX A;  4D52 A;  2F13 A;  2W20 A;  4KS3 A;  1MS9 A;  3H6J A;  1S0J A;  1MS3 A;  4AGT A;  2OJH A;  3VNG A;  1Z50 A;  2HTU A;  2HTR A;  5FNT A;  4B7M A;  1CQ1 A;  2QWI A;  4CPZ A;  1WCS A;  3NN9 A;  1E8U A;  2HU0 A;  1S0I A;  1B9V A;  1N1T A;  1ZGK A;  4XMA A;  4XHB A;  4ASC A;  2BER A;  1K32 A;  4HZZ A;  4CHB A;  1W8N A;  2AEQ A;  3TIB A;  1N6E A;  2B8H A;  2CML A;  2VW2 A;  4MZA A;  1MS0 A;  3BEQ A;  4YY8 A;  2YA5 A;  2DG1 A;  5D9D A;  4QN6 A;  3K36 A;  4GZS A;  1W1X A;  4KS4 A;  1EUS A;  3WW9 A;  2AEP A;  1V0E A;  2VSM A;  4AGI A;  2XZI A;  2F12 A;  3TI3 A;  4X47 A;  4YZ1 A;  1N7D A;  3K39 A;  1IVD A;  3PJQ A;  2QWE A;  1QBI A;  5M1Z A;  4GN9 A;  4GZP A;  4JML A;  2IAW A;  4CH9 A;  1L7H A;  5H47 A;  1V3E A;  2ZZK A;  2YA8 A;  3NO0 A;  5GX1 A;  4FP2 A;  1MS4 A;  3BYC A;  2W5O A;  5CGJ A;  3IAX A;  4M4V A;  4L7B A;  4B7R A;  1KIT A;  2FP9 A;  1H6L A;  4YZ4 A;  3B69 A;  3DAS A;  1RWL A;  4MWJ A;  4M4U A;  3TI5 A;  1IUC A;  3VNH A;  3K38 A;  2W8B B;  3G4H A;  4FPG A;  1NPE A;  1SNT A;  2BF6 A;  2XZK A;  3SAN A;  4MWY A;  2SLI A;  1SLI A;  2SIL A;  1SUU A;  3AMS A;  4B7N A;  4O5S A;  1Z4V A;  3CYE A; 
#chains in the Genus database with same CATH homology
 4D52 C;  4D52 A;  1IUB A;  5EO8 A;  4C1Y B;  4D52 B;  5EO7 A;  4AGT A;  4C1Y A;  4CSD A;  5H47 A;  1IUC A;  4AGI A;  4D4U A;  4UOU A;  4AHA A;  4AH4 A;  1OFZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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