4AHAA

Crystal structure of fucose binding lectin from aspergillus fumigatus (afl) in complex with fucosylated monosaccharides (fuc1-2gal, fuc1- 3glcnac, fuc1-4glcnac and fuc1-6glcnac)
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
314
structure length
314
Chain Sequence
STPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGTEKNVIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGGLGGAKFQVAPYSCIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKEGTNLGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGWYPDLVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVCWDHGKGYHDKGTITPVIQGSEVAIISWGSFANNGPDLRLYFQNGTYISAVSEWVWNRAHGSQLGRSALPPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent
pubmed doi rcsb
molecule keywords FUCOSE-SPECIFIC LECTIN FLEA
molecule tags Sugar binding protein
source organism Aspergillus fumigatus
total genus 80
structure length 314
sequence length 314
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07938 Fungal_lectin Fungal fucose-specific lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.70 Mainly Beta 6 Propeller Neuraminidase Fucose-specific lectin 4ahaA00
5EO7A 5EO8A 4C1YA 4CSDA 4AH4A 4D52C 5H47A 4AHAA 4D52B 4D52A 4UOUA 4AGIA 4AGTA 4C1YB 1IUCA 4D4UA 1OFZA 1IUBA
chains in the Genus database with same CATH superfamily
4M4VA 4AHAA 4GZPA 4MWJA 3SOQA 4CHBA 3SOVA 1INXA 4K1IA 4IN4A 5GX5A 1CRZA 4IFNX 2AH2A 4NN9A 4QNPA 4B7JA 2GVUA 2W5OA 2QWJA 4XJUA 4KS3A 4HHQA 4NCSA 1NCBN 5JYYA 1RWIA 1POOA 4MZAA 5EX7A 4GZQA 4L7DA 3K37A 4Q1UA 3FW0A 2QE8A 3FVZA 3TI5A 2YA4A 4B7RA 2HTYA 1ZGKA 3S94A 4SLIA 1S1DA 1IVBA 2VSMA 2QWEA 4XMBA 4YZ3A 1MS5A 3TI3A 2A75A 3NO0A 2IAWA 1ZI0A 2H2NA 2FPCA 3A72A 4FOQA 4X49A 3TIBA 4XJRA 1NNCA 4HZWA 3TI4A 1DILA 4FPOB 5EO7A 2AEQA 1IJQA 1DIMA 2C4LA 2XZKA 2V91A 1SLIA 2VK6A 2YA5A 5M1ZA 3HRPA 4GNBA 1V3CA 2OJHA 4PWZA 1W1XA 4XE9A 1SNTA 3VNHA 4FZHA 4K1KA 1B9VA 3A71A 4X6KA 2YDPA 3K3AA 2G8SA 2Z32A 3T1EA 1NN2A 1MS8A 4GZOA 2HT7A 1MS3A 2C4AA 1NSBA 3JU4A 1V0FA 1NCCN 2F25A 4GJTA 3B69A 2ZB6A 3CL0A 3E5ZA 1NCAN 4XJQA 3SLIA 1WCSA 4C1YB 3TICA 2POOA 3Q6KA 3K38A 4WA4A 3K39A 4R40A 4FQ4A 1NPEA 2BERA 2X9MA 1OFZA 3AMRA 2FP9A 4GEZA 4YW4A 4XJ9A 2HT5A 3V65B 3ADEA 1INWA 4X47A 2IAQA 2ISMA 4H53A 3ALWA 2W8BB 1WCQA 4XJAA 4XHXA 2IAOA 2QWGA 1L7GA 4XJZA 3LI4A 4GZWA 2VPJA 5D9DA 2DSOA 4L7CA 4IFLX 4KS1A 1W8OA 3DR2A 4HZXA 2F27A 3GVLA 4YW3A 4M4NA 4YW2A 4IMBA 5FWWA 4GNAA 2AEPA 4K1JA 1EUTA 5D9CA 2XN4A 5HUMA 3TIAA 1Z4VA 4XHBA 1MWEA 3NSSA 4MC7A 3W09A 1K32A 2FPBA 1E8TA 3WDZA 4FPHA 4D52B 4AH4A 1V04A 1NNBA 4MWVA 3UC1A 3ZGCA 4ASCA 3OPZA 4JMLA 4B7MA 3WW9A 5FZJA 3LI5A 3GVJA 4CPYA 1F8EA 2HTQA 3BEQA 2VW2A 2HU0A 2HTVA 1N1VA 2FP8A 4GZSA 4O5SA 1S0IA 2GVWA 4QN5A 4ZGCA 1N7DA 2BF6A 5GX3A 1VCJA 4K3YA 3ALXA 4G3NA 2VWDA 1IVCA 3CYEA 1INFA 2HTWA 1N6DA 5FNTA 3Q6PA 4FP3A 4HIZA 1W21A 1NCDN 1W0OA 1INVA 1CQ1A 1MS4A 1V2IA 4WA5A 1C5KA 5GX1A 3SALA 3ZGDA 1Z4YA 3U0SA 1MR5A 3H73A 1U6DX 1A4GA 2QWKA 2DYHA 4H52A 4BBWA 4DGRA 4HZVA 1SLLA 1B9TA 4MWXA 5FNUA 2YDTA 1F8BA 4QN3A 4YZ5A 3G4EA 4GDJA 4GZXA 4UOUA 2SILA 3WWAA 4WA3A 2HQSA 2F12A 1SUUA 4D8SA 2CMLA 1L7HA 4XILA 5HUNA 3CL2A 4Q6KA 3S8ZA 2ZB5A 2XCYA 4KS4A 3HLIA 1B9SA 5F9TA 4GZTA 3TI8A 3D11A 1C9UA 4YW1A 4MWRA 2AGSA 4B7QA 2DG0A 4XYXA 2RKCA 1KITA 2SIMA 4L7BA 5D9BA 4C1YA 2WOZA 3I1CA 4XIOA 3CKZA 4XIKA 2QWBA 1VCUA 4QN7A 3Q6TA 2HU4A 1V3BA 4CSDA 1W0PA 4D4UA 1Z4XA 2JKBA 3SREA 3A9GA 4CPNA 2F29A 1INGA 1XOEA 2QWCA 1IVEA 1F8DA 4FOWA 2VK7A 4QN4A 1BJIA 3P5BL 5B2DA 2IASA 1Z4ZA 3NN9A 1NSCA 2W8BA 4I00A 4NC5A 3KYAA 5H47A 4MX0A 3SOBB 1N1YA 4FPJA 2HT8A 4MWLA 2HTRA 4XJ8A 2YA8A 1L7FA 1Z50A 4FPLA 4FPCA 1MZ5A 3H72A 2F26A 1CRUA 2H2UA 1H6LA 1N6EA 2ZWAA 1SO7A 4D52A 1W8NA 6NN9A 3H71A 2IAPA 4MJUA 5CGJA 1USRA 5GX2A 3H6JA 1A14N 5HUGA 4GN8A 4GN7A 1IUBA 4FP2A 2W38A 4J9TA 1X2JA 2W5NA 3K36A 1V3DA 1EUUA 1EUSA 4IFJA 3AMSA 2YA7A 4ZY3A 4WEFA 5GTQA 3S8VA 4FPKA 5HX0A 4XMIA 4FPYA 4MWYA 3IAXA 2BATA 3V1SA 4MZEA 3O9JA 2QWAA 4IYGA 4FVKA 4GDIA 4M4UA 1IVFA 2QWHA 3VNGA 4ZLRA 2GVVA 2F13A 1XOGA 4XJWA 4GNCA 4N1BA 4GB1A 3SANA 2SLIA 4QN6A 4FPEA 1W20A 4XOGA 1NMCA 4FPFA 2F28A 3PJQA 3SRGA 2YA6A 1IVGA 2XZIA 3KGGA 5FNQA 3A9HA 1V0EA 3D12A 5NN9A 4DG6A 4GN9A 4B7NA 4IQKA 2W20A 2VW0A 1Q7FA 1MS1A 1E8UA 2IAVA 1USXA 4YZ2A 1S18A 2VVZA 4FPGA 3O4PA 1E1AA 4A0PA 2F0ZA 3G4HA 1WP5A 1Z4WA 1NMBN 4CH9A 1MS9A 5GX4A 2XZJA 2FHRA 3HLHA 4MJVA 4XMAA 2VK5A 4FOYA 4CPMA 4X4AA 4CPOA 1X2RA 4WEGA 4YY8A 2B8HA 1CVMA 2GVXA 3GVKA 2VAQA 4M3MA 4MWWA 4HZZA 1QLGA 2VSKA 1QBIA 3WN7A 2ZW9A 3B7EA 4HHOA 2FLUX 5FNSA 4UF7A 5B2CA 5EO8A 5FZNA 2IAUA 4MWQA 2QWDA 4K1HA 1N6FA 5HUKA 1V0ZA 3TC9A 1NSDA 4KS2A 3INBA 1E8VA 4AGIA 2P4OA 4YW5A 4JF7A 4O5TA 4HZYA 3SILA 3L6VA 2DG1A 1IVDA 1NMAN 2ZZKA 4HW6A 1MS0A 1V3EA 4CPZA 3V64C 2QWIA 2BZDA 2HTUA 3S2KA 3O9KA 4MWUA 2IATA 1N1TA 1MZ6A 2GHSA 3TI6A 3LI3A 1F8CA 1INYA 4AGTA 4FJ6A 1PJXA 1EURA 4KS5A 7NN9A 3DASA 2F11A 4CPLA 2IARA 4YZ4A 3BYCA 1N1SA 1INHA 1S0JA 2IVZA 3II7A 2F10A 2QWFA 5F72C 4D52C 4YZ1A 1NNAA 1IUCA 2F24A 1A4QA 1RWLA 2IAXA 2VW1A 4FOVA 5FNRA
chains in the Genus database with same CATH topology
5EO7A 5EO8A 4C1YA 4CSDA 4AH4A 4D52C 5H47A 4AHAA 4D52B 4D52A 4UOUA 4AGIA 4AGTA 4C1YB 1IUCA 4D4UA 1OFZA 1IUBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EO7 A;  5EO8 A;  4C1Y A;  4CSD A;  4AH4 A;  4D52 C;  5H47 A;  4AHA A;  4D52 B;  4D52 A;  4UOU A;  4AGI A;  4AGT A;  4C1Y B;  1IUC A;  4D4U A;  1OFZ A;  1IUB A; 
#chains in the Genus database with same CATH topology
 4M4V A;  4AHA A;  4GZP A;  4MWJ A;  3SOQ A;  4CHB A;  3SOV A;  1INX A;  4K1I A;  4IN4 A;  5GX5 A;  1CRZ A;  4IFN X;  2AH2 A;  4NN9 A;  4QNP A;  4B7J A;  2GVU A;  2W5O A;  2QWJ A;  4XJU A;  4KS3 A;  4HHQ A;  4NCS A;  1NCB N;  5JYY A;  1RWI A;  1POO A;  4MZA A;  5EX7 A;  4GZQ A;  4L7D A;  3K37 A;  4Q1U A;  3FW0 A;  2QE8 A;  3FVZ A;  3TI5 A;  2YA4 A;  4B7R A;  2HTY A;  1ZGK A;  3S94 A;  4SLI A;  1S1D A;  1IVB A;  2VSM A;  2QWE A;  4XMB A;  4YZ3 A;  1MS5 A;  3TI3 A;  2A75 A;  3NO0 A;  2IAW A;  1ZI0 A;  2H2N A;  2FPC A;  3A72 A;  4FOQ A;  4X49 A;  3TIB A;  4XJR A;  1NNC A;  4HZW A;  3TI4 A;  1DIL A;  4FPO B;  5EO7 A;  2AEQ A;  1IJQ A;  1DIM A;  2C4L A;  2XZK A;  2V91 A;  1SLI A;  2VK6 A;  2YA5 A;  5M1Z A;  3HRP A;  4GNB A;  1V3C A;  2OJH A;  4PWZ A;  1W1X A;  4XE9 A;  1SNT A;  3VNH A;  4FZH A;  4K1K A;  1B9V A;  3A71 A;  4X6K A;  2YDP A;  3K3A A;  2G8S A;  2Z32 A;  3T1E A;  1NN2 A;  1MS8 A;  4GZO A;  2HT7 A;  1MS3 A;  2C4A A;  1NSB A;  3JU4 A;  1V0F A;  1NCC N;  2F25 A;  4GJT A;  3B69 A;  2ZB6 A;  3CL0 A;  3E5Z A;  1NCA N;  4XJQ A;  3SLI A;  1WCS A;  4C1Y B;  3TIC A;  2POO A;  3Q6K A;  3K38 A;  4WA4 A;  3K39 A;  4R40 A;  4FQ4 A;  1NPE A;  2BER A;  2X9M A;  1OFZ A;  3AMR A;  2FP9 A;  4GEZ A;  4YW4 A;  4XJ9 A;  2HT5 A;  3V65 B;  3ADE A;  1INW A;  4X47 A;  2IAQ A;  2ISM A;  4H53 A;  3ALW A;  2W8B B;  1WCQ A;  4XJA A;  4XHX A;  2IAO A;  2QWG A;  1L7G A;  4XJZ A;  3LI4 A;  4GZW A;  2VPJ A;  5D9D A;  2DSO A;  4L7C A;  4IFL X;  4KS1 A;  1W8O A;  3DR2 A;  4HZX A;  2F27 A;  3GVL A;  4YW3 A;  4M4N A;  4YW2 A;  4IMB A;  5FWW A;  4GNA A;  2AEP A;  4K1J A;  1EUT A;  5D9C A;  2XN4 A;  5HUM A;  3TIA A;  1Z4V A;  4XHB A;  1MWE A;  3NSS A;  4MC7 A;  3W09 A;  1K32 A;  2FPB A;  1E8T A;  3WDZ A;  4FPH A;  4D52 B;  4AH4 A;  1V04 A;  1NNB A;  4MWV A;  3UC1 A;  3ZGC A;  4ASC A;  3OPZ A;  4JML A;  4B7M A;  3WW9 A;  5FZJ A;  3LI5 A;  3GVJ A;  4CPY A;  1F8E A;  2HTQ A;  3BEQ A;  2VW2 A;  2HU0 A;  2HTV A;  1N1V A;  2FP8 A;  4GZS A;  4O5S A;  1S0I A;  2GVW A;  4QN5 A;  4ZGC A;  1N7D A;  2BF6 A;  5GX3 A;  1VCJ A;  4K3Y A;  3ALX A;  4G3N A;  2VWD A;  1IVC A;  3CYE A;  1INF A;  2HTW A;  1N6D A;  5FNT A;  3Q6P A;  4FP3 A;  4HIZ A;  1W21 A;  1NCD N;  1W0O A;  1INV A;  1CQ1 A;  1MS4 A;  1V2I A;  4WA5 A;  1C5K A;  5GX1 A;  3SAL A;  3ZGD A;  1Z4Y A;  3U0S A;  1MR5 A;  3H73 A;  1U6D X;  1A4G A;  2QWK A;  2DYH A;  4H52 A;  4BBW A;  4DGR A;  4HZV A;  1SLL A;  1B9T A;  4MWX A;  5FNU A;  2YDT A;  1F8B A;  4QN3 A;  4YZ5 A;  3G4E A;  4GDJ A;  4GZX A;  4UOU A;  2SIL A;  3WWA A;  4WA3 A;  2HQS A;  2F12 A;  1SUU A;  4D8S A;  2CML A;  1L7H A;  4XIL A;  5HUN A;  3CL2 A;  4Q6K A;  3S8Z A;  2ZB5 A;  2XCY A;  4KS4 A;  3HLI A;  1B9S A;  5F9T A;  4GZT A;  3TI8 A;  3D11 A;  1C9U A;  4YW1 A;  4MWR A;  2AGS A;  4B7Q A;  2DG0 A;  4XYX A;  2RKC A;  1KIT A;  2SIM A;  4L7B A;  5D9B A;  4C1Y A;  2WOZ A;  3I1C A;  4XIO A;  3CKZ A;  4XIK A;  2QWB A;  1VCU A;  4QN7 A;  3Q6T A;  2HU4 A;  1V3B A;  4CSD A;  1W0P A;  4D4U A;  1Z4X A;  2JKB A;  3SRE A;  3A9G A;  4CPN A;  2F29 A;  1ING A;  1XOE A;  2QWC A;  1IVE A;  1F8D A;  4FOW A;  2VK7 A;  4QN4 A;  1BJI A;  3P5B L;  5B2D A;  2IAS A;  1Z4Z A;  3NN9 A;  1NSC A;  2W8B A;  4I00 A;  4NC5 A;  3KYA A;  5H47 A;  4MX0 A;  3SOB B;  1N1Y A;  4FPJ A;  2HT8 A;  4MWL A;  2HTR A;  4XJ8 A;  2YA8 A;  1L7F A;  1Z50 A;  4FPL A;  4FPC A;  1MZ5 A;  3H72 A;  2F26 A;  1CRU A;  2H2U A;  1H6L A;  1N6E A;  2ZWA A;  1SO7 A;  4D52 A;  1W8N A;  6NN9 A;  3H71 A;  2IAP A;  4MJU A;  5CGJ A;  1USR A;  5GX2 A;  3H6J A;  1A14 N;  5HUG A;  4GN8 A;  4GN7 A;  1IUB A;  4FP2 A;  2W38 A;  4J9T A;  1X2J A;  2W5N A;  3K36 A;  1V3D A;  1EUU A;  1EUS A;  4IFJ A;  3AMS A;  2YA7 A;  4ZY3 A;  4WEF A;  5GTQ A;  3S8V A;  4FPK A;  5HX0 A;  4XMI A;  4FPY A;  4MWY A;  3IAX A;  2BAT A;  3V1S A;  4MZE A;  3O9J A;  2QWA A;  4IYG A;  4FVK A;  4GDI A;  4M4U A;  1IVF A;  2QWH A;  3VNG A;  4ZLR A;  2GVV A;  2F13 A;  1XOG A;  4XJW A;  4GNC A;  4N1B A;  4GB1 A;  3SAN A;  2SLI A;  4QN6 A;  4FPE A;  1W20 A;  4XOG A;  1NMC A;  4FPF A;  2F28 A;  3PJQ A;  3SRG A;  2YA6 A;  1IVG A;  2XZI A;  3KGG A;  5FNQ A;  3A9H A;  1V0E A;  3D12 A;  5NN9 A;  4DG6 A;  4GN9 A;  4B7N A;  4IQK A;  2W20 A;  2VW0 A;  1Q7F A;  1MS1 A;  1E8U A;  2IAV A;  1USX A;  4YZ2 A;  1S18 A;  2VVZ A;  4FPG A;  3O4P A;  1E1A A;  4A0P A;  2F0Z A;  3G4H A;  1WP5 A;  1Z4W A;  1NMB N;  4CH9 A;  1MS9 A;  5GX4 A;  2XZJ A;  2FHR A;  3HLH A;  4MJV A;  4XMA A;  2VK5 A;  4FOY A;  4CPM A;  4X4A A;  4CPO A;  1X2R A;  4WEG A;  4YY8 A;  2B8H A;  1CVM A;  2GVX A;  3GVK A;  2VAQ A;  4M3M A;  4MWW A;  4HZZ A;  1QLG A;  2VSK A;  1QBI A;  3WN7 A;  2ZW9 A;  3B7E A;  4HHO A;  2FLU X;  5FNS A;  4UF7 A;  5B2C A;  5EO8 A;  5FZN A;  2IAU A;  4MWQ A;  2QWD A;  4K1H A;  1N6F A;  5HUK A;  1V0Z A;  3TC9 A;  1NSD A;  4KS2 A;  3INB A;  1E8V A;  4AGI A;  2P4O A;  4YW5 A;  4JF7 A;  4O5T A;  4HZY A;  3SIL A;  3L6V A;  2DG1 A;  1IVD A;  1NMA N;  2ZZK A;  4HW6 A;  1MS0 A;  1V3E A;  4CPZ A;  3V64 C;  2QWI A;  2BZD A;  2HTU A;  3S2K A;  3O9K A;  4MWU A;  2IAT A;  1N1T A;  1MZ6 A;  2GHS A;  3TI6 A;  3LI3 A;  1F8C A;  1INY A;  4AGT A;  4FJ6 A;  1PJX A;  1EUR A;  4KS5 A;  7NN9 A;  3DAS A;  2F11 A;  4CPL A;  2IAR A;  4YZ4 A;  3BYC A;  1N1S A;  1INH A;  1S0J A;  2IVZ A;  3II7 A;  2F10 A;  2QWF A;  5F72 C;  4D52 C;  4YZ1 A;  1NNA A;  1IUC A;  2F24 A;  1A4Q A;  1RWL A;  2IAX A;  2VW1 A;  4FOV A;  5FNR A; 
#chains in the Genus database with same CATH homology
 5EO7 A;  5EO8 A;  4C1Y A;  4CSD A;  4AH4 A;  4D52 C;  5H47 A;  4AHA A;  4D52 B;  4D52 A;  4UOU A;  4AGI A;  4AGT A;  4C1Y B;  1IUC A;  4D4U A;  1OFZ A;  1IUB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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