4AKVA

Crystal structure of human sorting nexin 33 (snx33)
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
363
structure length
345
Chain Sequence
MYSIEMGPRGPQWKANPHPFACSVEDPISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Human Sorting Nexin 33
rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SORTING NEXIN-33
total genus 140
structure length 345
sequence length 363
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00787 PX PX domain
A PF10456 BAR_3_WASP_bdg WASP-binding domain of Sorting nexin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4akvA02
3.30.1520.10 Alpha Beta 2-Layer Sandwich PX Domain Phox-like domain 4akvA01
5C5BA 2IWLX 4DYLA 3OK8A 1KMDA 2CZOA 2ELBA 1KQ6A 3G9GA 3FOGA 1I4DA 2AR5A 2Z0OA 2DYBA 4ON3A 4AZ9A 2I4KA 1I4TA 1URUA 4OXWA 3Q0KA 4IKBB 2X3VA 1X03A 4AVMA 2V6VA 3QE6A 1ZWWA 2RAJA 3CAZA 1H6HA 1GD5A 4I1QA 1O7KA 4P2IA 1WDZA 2EFKA 2Q13A 4IKDA 1XTNA 3SOGA 4AKVA 3IQ2A 4WPEA 3PLTA 2Q12A 4NQIA 2FICA 4PZGA 3HAIA 3SYVA 2ETTA 4PQOA 2X3XA 4ATMA 1OCUA 2V14A 2CSKA 1I49A 5C5BB 2RAIA 4P2JA 2V0OA 3HPBA 3I2WA 3ACOA 4IKBA 2RAKA 4DCNC 4BNEA 1I4LA 3HAJA 4WPCA 3HPCX 3LLLA 1X04A 3M3WA 2YPSA 2YKTA 2Z0NA 3QNIA 3Q84A 1Y2OA 2C08A 2Z0VA 2WWEA 3P0CA 3QWEA 3ABHA 2EFLA 2D4CA 3HAHA 3DYTA 4HASA 1OCSA 2L73A 4BGJA 2X3WA 3LUIA 2REAA 2REDA 4FZSA 4PQPA 2D1LA 4H8SA 4NSWA 1XTEA
chains in the Genus database with same CATH superfamily
4EZOA 3I01A 1KMDA 4PO2A 2QFFA 4KIKB 1GNTA 3EJTA 1KQ6A 4IW0A 1I4DA 4AZGA 3BVXA 2Z0OA 2FYVA 4EZNA 2DYBA 4ON3A 3BVTA 3DDFA 3F7WA 2X3VA 2ND0A 4AVMA 4JWIA 4R5IA 4R5LA 3O3NB 3D51A 2YI9A 1QX1A 5FLEX 2EFKA 4EZZA 2YL8A 3O3MB 4IKDA 2QXLA 4H6HA 3D50A 4AKVA 4JLCA 4PZGA 3HAIA 3T47A 1TQSA 3ER8C 4ATMA 2V14A 2X5CA 2CSKA 5C5BB 1R34A 1GN9A 2V0OA 3T48A 4IKBA 1SU6A 2OBLA 4DCNC 4BNEA 4WPCA 2MI7A 1DKXA 3DX0A 3EJPA 3M3WA 3D4YA 1SU7A 4D8JA 2Z0VA 3DPQA 4F01A 3P0CA 1GNLA 3QWEA 2EFLA 1QWUA 3BUPA 3C7NA 1OA1A 3KAVA 2YI8A 4AZBA 3RV0A 2YLLA 1E9VA 2GA9D 3OHXM 3OK8A 4M0MA 1ZYLA 4EZTA 2F7OA 4B9QA 3LMFA 2EX3B 2PY6A 3G9GA 3DX4A 2OBMA 2OW6A 2ND1A 2F7QA 1I4TA 4OXWA 2YIVX 5KBPA 3EJRA 2F7RA 1ZWWA 2JNSA 2QKWA 3D52A 3VEBA 1TQTA 1WDZA 1DKZA 3L3PA 4AZ7A 1MJGA 3CKDA 2Q12A 3VEAA 2Z8YA 4EZSA 3I04A 4AZIA 2F1AA 2WINM 4P2JA 3KAWA 4F00A 1OA0A 1I4LA 3HAJA 2JNKA 2ALWA 4EZYA 3BVWA 3FD9A 5FIGA 2YPSA 3BUIA 3QNIA 1Y2OA 1R33A 2C08A 1O7DB 3B51X 3BUBA 2D4CA 3DYTA 1YWMA 4AZ6A 4JWCA 1HTYA 4BGJA 2LM0A 3ERCC 3BUDA 4NSWA 3OWGA 2YL9A 2LXYA 1DKYA 2IWLX 3BLBA 3GI7A 2CZOA 4HR1A 4IWPA 3D4ZA 1U00A 4EZRA 4AZ9A 3CZNA 3B53X 3EJUA 4IM2A 3CV5A 3DX3A 4AZHA 3Q0KA 2YLAA 4IKBB 2EWFA 3BVVA 2NCZA 1X03A 3KDRA 4HY9A 3QE6A 4IWOA 2RAJA 1GD5A 2PMRA 4I1QA 1O7KA 2GF4A 4P2IA 1OAOA 4FZOA 2KHOA 2F1BA 3BUQA 1XTNA 3T4AG 3SOGA 4HYBA 3RPMA 4FZPA 4UDYX 3PLTA 4NQIA 3T46A 4R5KA 4IM3A 2X3XA 4FM3A 1OCUA 4JN4A 1I49A 3BVUA 2RAIA 2YL6A 4AZ5A 1UPXA 3ACOA 1SU8A 2RAKA 2O0I1 3HPCX 4UDXX 4EZQA 3DX2A 3CVRA 3LLLA 1X04A 4R5GA 2YKTA 2YL5A 2WWEA 3A98A 1E2UA 4IM0A 2F7PA 4HASA 1OCSA 2L73A 4EZVA 3DPPA 2X3WA 2REAA 2REDA 2D1LA 1XTEA 5C5BA 4JL9A 4DYLA 1E1DA 3D2FA 4NPHA 3RV1A 3DX1A 4H6IA 1W9MA 2ELBA 3LVTA 3FOGA 3QA8A 2AR5A 2I4KA 3DPOA 2ZXQA 1URUA 3CZSA 3L3OM 5TKYA 3UITA 3ER9B 5E84A 2YIAA 2V6VA 1R5EA 2RT6A 3CAZA 1H6HA 4E3CA 4IWQA 2Q13A 1TQUA 3QNJA 1PS3A 2YIBA 3EJSA 1TQVA 2OO2A 4G6QA 3B52X 3O3OB 4EZUA 3IQ2A 4WPEA 2OW7A 1SUFA 1TQWA 2FICA 1LQ7A 3SYVA 2ETTA 4PQOA 1HWWA 4AZCA 4EZWA 3ZEDA 4JNEA 1JQKA 4EZPA 3EJQA 3I2WA 3HPBA 3DDGA 4HR1B 2WYIA 1QWNA 2OZNB 4R5JA 4KIKA 2F18A 3VKHA 4JWEA 2Z0NA 3Q84A 2WYHA 3I39X 1O7DC 3ABHA 4JWDA 4AZCB 3HAHA 3T49A 4EZXA 1HXKA 4JNFA 2N3KA 3D2EA 3LUIA 4E81A 2GAFD 4FZSA 4PQPA 4H8SA
chains in the Genus database with same CATH topology
5C5BA 2IWLX 4DYLA 3OK8A 1KMDA 2CZOA 2ELBA 1KQ6A 3G9GA 3FOGA 1I4DA 2AR5A 2Z0OA 2DYBA 4ON3A 4AZ9A 2I4KA 1I4TA 1URUA 4OXWA 3Q0KA 4IKBB 2X3VA 1X03A 4AVMA 2V6VA 3QE6A 1ZWWA 2RAJA 3CAZA 1H6HA 1GD5A 4I1QA 1O7KA 4P2IA 1WDZA 2EFKA 2Q13A 4IKDA 1XTNA 3SOGA 4AKVA 3IQ2A 4WPEA 3PLTA 2Q12A 4NQIA 2FICA 4PZGA 3HAIA 3SYVA 2ETTA 4PQOA 2X3XA 4ATMA 1OCUA 2V14A 2CSKA 1I49A 5C5BB 2RAIA 4P2JA 2V0OA 3HPBA 3I2WA 3ACOA 4IKBA 2RAKA 4DCNC 4BNEA 1I4LA 3HAJA 4WPCA 3HPCX 3LLLA 1X04A 3M3WA 2YPSA 2YKTA 2Z0NA 3QNIA 3Q84A 1Y2OA 2C08A 2Z0VA 2WWEA 3P0CA 3QWEA 3ABHA 2EFLA 2D4CA 3HAHA 3DYTA 4HASA 1OCSA 2L73A 4BGJA 2X3WA 3LUIA 2REAA 2REDA 4FZSA 4PQPA 2D1LA 4H8SA 4NSWA 1XTEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5B A;  2IWL X;  4DYL A;  3OK8 A;  1KMD A;  2CZO A;  2ELB A;  1KQ6 A;  3G9G A;  3FOG A;  1I4D A;  2AR5 A;  2Z0O A;  2DYB A;  4ON3 A;  4AZ9 A;  2I4K A;  1I4T A;  1URU A;  4OXW A;  3Q0K A;  4IKB B;  2X3V A;  1X03 A;  4AVM A;  2V6V A;  3QE6 A;  1ZWW A;  2RAJ A;  3CAZ A;  1H6H A;  1GD5 A;  4I1Q A;  1O7K A;  4P2I A;  1WDZ A;  2EFK A;  2Q13 A;  4IKD A;  1XTN A;  3SOG A;  4AKV A;  3IQ2 A;  4WPE A;  3PLT A;  2Q12 A;  4NQI A;  2FIC A;  4PZG A;  3HAI A;  3SYV A;  2ETT A;  4PQO A;  2X3X A;  4ATM A;  1OCU A;  2V14 A;  2CSK A;  1I49 A;  5C5B B;  2RAI A;  4P2J A;  2V0O A;  3HPB A;  3I2W A;  3ACO A;  4IKB A;  2RAK A;  4DCN C;  4BNE A;  1I4L A;  3HAJ A;  4WPC A;  3HPC X;  3LLL A;  1X04 A;  3M3W A;  2YPS A;  2YKT A;  2Z0N A;  3QNI A;  3Q84 A;  1Y2O A;  2C08 A;  2Z0V A;  2WWE A;  3P0C A;  3QWE A;  3ABH A;  2EFL A;  2D4C A;  3HAH A;  3DYT A;  4HAS A;  1OCS A;  2L73 A;  4BGJ A;  2X3W A;  3LUI A;  2REA A;  2RED A;  4FZS A;  4PQP A;  2D1L A;  4H8S A;  4NSW A;  1XTE A; 
#chains in the Genus database with same CATH topology
 4EZO A;  3I01 A;  1KMD A;  4PO2 A;  2QFF A;  4KIK B;  1GNT A;  3EJT A;  1KQ6 A;  4IW0 A;  1I4D A;  4AZG A;  3BVX A;  2Z0O A;  2FYV A;  4EZN A;  2DYB A;  4ON3 A;  3BVT A;  3DDF A;  3F7W A;  2X3V A;  2ND0 A;  4AVM A;  4JWI A;  4R5I A;  4R5L A;  3O3N B;  3D51 A;  2YI9 A;  1QX1 A;  5FLE X;  2EFK A;  4EZZ A;  2YL8 A;  3O3M B;  4IKD A;  2QXL A;  4H6H A;  3D50 A;  4AKV A;  4JLC A;  4PZG A;  3HAI A;  3T47 A;  1TQS A;  3ER8 C;  4ATM A;  2V14 A;  2X5C A;  2CSK A;  5C5B B;  1R34 A;  1GN9 A;  2V0O A;  3T48 A;  4IKB A;  1SU6 A;  2OBL A;  4DCN C;  4BNE A;  4WPC A;  2MI7 A;  1DKX A;  3DX0 A;  3EJP A;  3M3W A;  3D4Y A;  1SU7 A;  4D8J A;  2Z0V A;  3DPQ A;  4F01 A;  3P0C A;  1GNL A;  3QWE A;  2EFL A;  1QWU A;  3BUP A;  3C7N A;  1OA1 A;  3KAV A;  2YI8 A;  4AZB A;  3RV0 A;  2YLL A;  1E9V A;  2GA9 D;  3OHX M;  3OK8 A;  4M0M A;  1ZYL A;  4EZT A;  2F7O A;  4B9Q A;  3LMF A;  2EX3 B;  2PY6 A;  3G9G A;  3DX4 A;  2OBM A;  2OW6 A;  2ND1 A;  2F7Q A;  1I4T A;  4OXW A;  2YIV X;  5KBP A;  3EJR A;  2F7R A;  1ZWW A;  2JNS A;  2QKW A;  3D52 A;  3VEB A;  1TQT A;  1WDZ A;  1DKZ A;  3L3P A;  4AZ7 A;  1MJG A;  3CKD A;  2Q12 A;  3VEA A;  2Z8Y A;  4EZS A;  3I04 A;  4AZI A;  2F1A A;  2WIN M;  4P2J A;  3KAW A;  4F00 A;  1OA0 A;  1I4L A;  3HAJ A;  2JNK A;  2ALW A;  4EZY A;  3BVW A;  3FD9 A;  5FIG A;  2YPS A;  3BUI A;  3QNI A;  1Y2O A;  1R33 A;  2C08 A;  1O7D B;  3B51 X;  3BUB A;  2D4C A;  3DYT A;  1YWM A;  4AZ6 A;  4JWC A;  1HTY A;  4BGJ A;  2LM0 A;  3ERC C;  3BUD A;  4NSW A;  3OWG A;  2YL9 A;  2LXY A;  1DKY A;  2IWL X;  3BLB A;  3GI7 A;  2CZO A;  4HR1 A;  4IWP A;  3D4Z A;  1U00 A;  4EZR A;  4AZ9 A;  3CZN A;  3B53 X;  3EJU A;  4IM2 A;  3CV5 A;  3DX3 A;  4AZH A;  3Q0K A;  2YLA A;  4IKB B;  2EWF A;  3BVV A;  2NCZ A;  1X03 A;  3KDR A;  4HY9 A;  3QE6 A;  4IWO A;  2RAJ A;  1GD5 A;  2PMR A;  4I1Q A;  1O7K A;  2GF4 A;  4P2I A;  1OAO A;  4FZO A;  2KHO A;  2F1B A;  3BUQ A;  1XTN A;  3T4A G;  3SOG A;  4HYB A;  3RPM A;  4FZP A;  4UDY X;  3PLT A;  4NQI A;  3T46 A;  4R5K A;  4IM3 A;  2X3X A;  4FM3 A;  1OCU A;  4JN4 A;  1I49 A;  3BVU A;  2RAI A;  2YL6 A;  4AZ5 A;  1UPX A;  3ACO A;  1SU8 A;  2RAK A;  2O0I 1;  3HPC X;  4UDX X;  4EZQ A;  3DX2 A;  3CVR A;  3LLL A;  1X04 A;  4R5G A;  2YKT A;  2YL5 A;  2WWE A;  3A98 A;  1E2U A;  4IM0 A;  2F7P A;  4HAS A;  1OCS A;  2L73 A;  4EZV A;  3DPP A;  2X3W A;  2REA A;  2RED A;  2D1L A;  1XTE A;  5C5B A;  4JL9 A;  4DYL A;  1E1D A;  3D2F A;  4NPH A;  3RV1 A;  3DX1 A;  4H6I A;  1W9M A;  2ELB A;  3LVT A;  3FOG A;  3QA8 A;  2AR5 A;  2I4K A;  3DPO A;  2ZXQ A;  1URU A;  3CZS A;  3L3O M;  5TKY A;  3UIT A;  3ER9 B;  5E84 A;  2YIA A;  2V6V A;  1R5E A;  2RT6 A;  3CAZ A;  1H6H A;  4E3C A;  4IWQ A;  2Q13 A;  1TQU A;  3QNJ A;  1PS3 A;  2YIB A;  3EJS A;  1TQV A;  2OO2 A;  4G6Q A;  3B52 X;  3O3O B;  4EZU A;  3IQ2 A;  4WPE A;  2OW7 A;  1SUF A;  1TQW A;  2FIC A;  1LQ7 A;  3SYV A;  2ETT A;  4PQO A;  1HWW A;  4AZC A;  4EZW A;  3ZED A;  4JNE A;  1JQK A;  4EZP A;  3EJQ A;  3I2W A;  3HPB A;  3DDG A;  4HR1 B;  2WYI A;  1QWN A;  2OZN B;  4R5J A;  4KIK A;  2F18 A;  3VKH A;  4JWE A;  2Z0N A;  3Q84 A;  2WYH A;  3I39 X;  1O7D C;  3ABH A;  4JWD A;  4AZC B;  3HAH A;  3T49 A;  4EZX A;  1HXK A;  4JNF A;  2N3K A;  3D2E A;  3LUI A;  4E81 A;  2GAF D;  4FZS A;  4PQP A;  4H8S A; 
#chains in the Genus database with same CATH homology
 5C5B A;  2IWL X;  4DYL A;  3OK8 A;  1KMD A;  2CZO A;  2ELB A;  1KQ6 A;  3G9G A;  3FOG A;  1I4D A;  2AR5 A;  2Z0O A;  2DYB A;  4ON3 A;  4AZ9 A;  2I4K A;  1I4T A;  1URU A;  4OXW A;  3Q0K A;  4IKB B;  2X3V A;  1X03 A;  4AVM A;  2V6V A;  3QE6 A;  1ZWW A;  2RAJ A;  3CAZ A;  1H6H A;  1GD5 A;  4I1Q A;  1O7K A;  4P2I A;  1WDZ A;  2EFK A;  2Q13 A;  4IKD A;  1XTN A;  3SOG A;  4AKV A;  3IQ2 A;  4WPE A;  3PLT A;  2Q12 A;  4NQI A;  2FIC A;  4PZG A;  3HAI A;  3SYV A;  2ETT A;  4PQO A;  2X3X A;  4ATM A;  1OCU A;  2V14 A;  2CSK A;  1I49 A;  5C5B B;  2RAI A;  4P2J A;  2V0O A;  3HPB A;  3I2W A;  3ACO A;  4IKB A;  2RAK A;  4DCN C;  4BNE A;  1I4L A;  3HAJ A;  4WPC A;  3HPC X;  3LLL A;  1X04 A;  3M3W A;  2YPS A;  2YKT A;  2Z0N A;  3QNI A;  3Q84 A;  1Y2O A;  2C08 A;  2Z0V A;  2WWE A;  3P0C A;  3QWE A;  3ABH A;  2EFL A;  2D4C A;  3HAH A;  3DYT A;  4HAS A;  1OCS A;  2L73 A;  4BGJ A;  2X3W A;  3LUI A;  2REA A;  2RED A;  4FZS A;  4PQP A;  2D1L A;  4H8S A;  4NSW A;  1XTE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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